NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767912360|ref|XP_011542463|]
View 

piggyBac transposable element-derived protein 2 isoform X1 [Homo sapiens]

Protein Classification

transposase( domain architecture ID 10620044)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
140-499 8.83e-123

Transposase IS4;


:

Pssm-ID: 433521  Cd Length: 349  Bit Score: 366.24  E-value: 8.83e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  140 SPVGLFELFFDEGTINFIVNETNRYAWQKNVNLSLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRD 219
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQKYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMFYGNPGLRDAMSRE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  220 RFELIFSYLHFADNNELDA-SDRFAKVRPLIIRMNCNFQKHAPLEEFYSFGESMCEYFGHRGSKQLHRGKPVRLGYKIWC 298
Cdd:pfam13843  81 RFEFLLSALHFADNPTRKAeTDKLGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPFKQYLPGKPRKNGIKLHV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  299 GTTS-RGYLVWFEPSQGTLFTKPD-RSLDLGGSMVIKFVDALQERGflpYHIFFDKVFTSVKLMSILRKKGVKATGTVRE 376
Cdd:pfam13843 161 LCDAqTGYIIALELYEGPARNGRNsRQLGKRNALVLRLTEPLQGQG---RHVYFDNFYTSLDLAQELAKKGTYATGTLRK 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  377 YRTercplKDPKEL-KKMKRGSFDYKVDesEEIIVCRWHDSSVVNICSNAVGIEPVRLTSRHSGaaktrtQVHQPSLVKL 455
Cdd:pfam13843 238 NRY-----GLPKDLtQQLPPGSILARYG--GPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQ------KIARPKLVED 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 767912360  456 YQEKVGGVGRMDQNIAKYKVKIRG-MKWYSSFIGYVIDAALNNAW 499
Cdd:pfam13843 305 YNQAKGAVDRHDQLLAAYRVSRKGsKKWYKRVFIFLLNIAVVNAY 349
 
Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
140-499 8.83e-123

Transposase IS4;


Pssm-ID: 433521  Cd Length: 349  Bit Score: 366.24  E-value: 8.83e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  140 SPVGLFELFFDEGTINFIVNETNRYAWQKNVNLSLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRD 219
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQKYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMFYGNPGLRDAMSRE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  220 RFELIFSYLHFADNNELDA-SDRFAKVRPLIIRMNCNFQKHAPLEEFYSFGESMCEYFGHRGSKQLHRGKPVRLGYKIWC 298
Cdd:pfam13843  81 RFEFLLSALHFADNPTRKAeTDKLGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPFKQYLPGKPRKNGIKLHV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  299 GTTS-RGYLVWFEPSQGTLFTKPD-RSLDLGGSMVIKFVDALQERGflpYHIFFDKVFTSVKLMSILRKKGVKATGTVRE 376
Cdd:pfam13843 161 LCDAqTGYIIALELYEGPARNGRNsRQLGKRNALVLRLTEPLQGQG---RHVYFDNFYTSLDLAQELAKKGTYATGTLRK 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  377 YRTercplKDPKEL-KKMKRGSFDYKVDesEEIIVCRWHDSSVVNICSNAVGIEPVRLTSRHSGaaktrtQVHQPSLVKL 455
Cdd:pfam13843 238 NRY-----GLPKDLtQQLPPGSILARYG--GPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQ------KIARPKLVED 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 767912360  456 YQEKVGGVGRMDQNIAKYKVKIRG-MKWYSSFIGYVIDAALNNAW 499
Cdd:pfam13843 305 YNQAKGAVDRHDQLLAAYRVSRKGsKKWYKRVFIFLLNIAVVNAY 349
 
Name Accession Description Interval E-value
DDE_Tnp_1_7 pfam13843
Transposase IS4;
140-499 8.83e-123

Transposase IS4;


Pssm-ID: 433521  Cd Length: 349  Bit Score: 366.24  E-value: 8.83e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  140 SPVGLFELFFDEGTINFIVNETNRYAWQKNVNLSLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRD 219
Cdd:pfam13843   1 DPVELFELFLDDEIIARIVRETNLYAKQKYKWLPLTAEELMAFLGLLILMGDVRLPSVEDYWSTKMFYGNPGLRDAMSRE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  220 RFELIFSYLHFADNNELDA-SDRFAKVRPLIIRMNCNFQKHAPLEEFYSFGESMCEYFGHRGSKQLHRGKPVRLGYKIWC 298
Cdd:pfam13843  81 RFEFLLSALHFADNPTRKAeTDKLGKIRPLIDYLNENMQKVYRPSQTLVLDESLILFKGRVPFKQYLPGKPRKNGIKLHV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  299 GTTS-RGYLVWFEPSQGTLFTKPD-RSLDLGGSMVIKFVDALQERGflpYHIFFDKVFTSVKLMSILRKKGVKATGTVRE 376
Cdd:pfam13843 161 LCDAqTGYIIALELYEGPARNGRNsRQLGKRNALVLRLTEPLQGQG---RHVYFDNFYTSLDLAQELAKKGTYATGTLRK 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767912360  377 YRTercplKDPKEL-KKMKRGSFDYKVDesEEIIVCRWHDSSVVNICSNAVGIEPVRLTSRHSGaaktrtQVHQPSLVKL 455
Cdd:pfam13843 238 NRY-----GLPKDLtQQLPPGSILARYG--GPLMLFKWRRRKVVLLLSTFSSDCLVYSKERSGQ------KIARPKLVED 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 767912360  456 YQEKVGGVGRMDQNIAKYKVKIRG-MKWYSSFIGYVIDAALNNAW 499
Cdd:pfam13843 305 YNQAKGAVDRHDQLLAAYRVSRKGsKKWYKRVFIFLLNIAVVNAY 349
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH