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Conserved domains on  [gi|1149835609|ref|XP_012609345|]
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LOW QUALITY PROTEIN: toll-like receptor 10 [Microcebus murinus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
631-732 2.55e-20

Toll - interleukin 1 - resistance;


:

Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 87.76  E-value: 2.55e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  631 QFHAFISYSEHVslWVKNELIPNLEKEDG*VLICLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYF 710
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100
                   ....*....|....*....|..
gi 1149835609  711 AHHDFFHENSDHIILTLLEPIP 732
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIP 100
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
349-522 6.70e-12

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 6.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 349 QYLNFANNILTDDrFKRTIQLPHLKTLILKGYRLErlSLASGFANNTPLKHLDLSQNLLQHKNDENCSWPEtLVTMNLSS 428
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLT--DLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN-LKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 429 NKFTD--SVFRCLTrNIPILDLNNNQIQTVSKEIIHLKSLQELNIAFSFLTDLPGCSYFRRLSILNIEMNLIlsPSLDFF 506
Cdd:COG4886   192 NQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQL--TDLPPL 268

                         170
                  ....*....|....*.
gi 1149835609 507 QSCQEAKTLNAGKNPF 522
Cdd:COG4886   269 ANLTNLKTLDLSNNQL 284
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
56-192 5.41e-09

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.18  E-value: 5.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFNKeLRYLDLSFNRLKIVTW-YSLASLRHLDLSFNDFETMPtg 134
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP-- 266

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1149835609 135 eETSNMSFLETLGLSEAKIQKSDFQKIAHLHLNTIFLALRTLSHYEEGSLPILNASIL 192
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323
LRRCT super family cl47026
Leucine rich repeat C-terminal domain;
520-572 1.54e-04

Leucine rich repeat C-terminal domain;


The actual alignment was detected with superfamily member smart00082:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 40.11  E-value: 1.54e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1149835609  520 NPFQCTCELRNFIQLEKYSEgmMVGWSDSYICEYPLNLKGtKLKDIHLPELSC 572
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE--HLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
 
Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
631-732 2.55e-20

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 87.76  E-value: 2.55e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  631 QFHAFISYSEHVslWVKNELIPNLEKEDG*VLICLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYF 710
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100
                   ....*....|....*....|..
gi 1149835609  711 AHHDFFHENSDHIILTLLEPIP 732
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIP 100
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
349-522 6.70e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 6.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 349 QYLNFANNILTDDrFKRTIQLPHLKTLILKGYRLErlSLASGFANNTPLKHLDLSQNLLQHKNDENCSWPEtLVTMNLSS 428
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLT--DLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN-LKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 429 NKFTD--SVFRCLTrNIPILDLNNNQIQTVSKEIIHLKSLQELNIAFSFLTDLPGCSYFRRLSILNIEMNLIlsPSLDFF 506
Cdd:COG4886   192 NQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQL--TDLPPL 268

                         170
                  ....*....|....*.
gi 1149835609 507 QSCQEAKTLNAGKNPF 522
Cdd:COG4886   269 ANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
56-192 5.41e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.18  E-value: 5.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFNKeLRYLDLSFNRLKIVTW-YSLASLRHLDLSFNDFETMPtg 134
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP-- 266

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1149835609 135 eETSNMSFLETLGLSEAKIQKSDFQKIAHLHLNTIFLALRTLSHYEEGSLPILNASIL 192
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323
LRR_8 pfam13855
Leucine rich repeat;
71-128 8.09e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 52.53  E-value: 8.09e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1149835609  71 SNLKVLILCHNRIQELNITISEFNKELRYLDLSFNRLKIV---TWYSLASLRHLDLSFNDF 128
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLspgAFSGLPSLRYLDLSGNRL 61
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 632-734 3.30e-07

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 50.83  E-value: 3.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 632 FHAFISYS-EHVSLWVKNELIPNLeKEDG*VLiCLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYF 710
Cdd:pfam01582   1 YDVFLSFRgSDTREWFVSHLLKEL-KQKGIKL-FIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVK 78

                          90       100
                  ....*....|....*....|....
gi 1149835609 711 AHHdFFHENSDHIILTLLEPIPFY 734
Cdd:pfam01582  79 ILE-CALDLGQKVIPIFYEVDPSD 101
LRRCT smart00082
Leucine rich repeat C-terminal domain;
520-572 1.54e-04

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 40.11  E-value: 1.54e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1149835609  520 NPFQCTCELRNFIQLEKYSEgmMVGWSDSYICEYPLNLKGtKLKDIHLPELSC 572
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE--HLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
LRR_8 pfam13855
Leucine rich repeat;
370-431 1.84e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1149835609 370 PHLKTLILKGYRLERLSlASGFANNTPLKHLDLSQNLLQHKNDENCSWPETLVTMNLSSNKF 431
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD-DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
TIR smart00255
Toll - interleukin 1 - resistance;
631-732 2.55e-20

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 87.76  E-value: 2.55e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  631 QFHAFISYSEHVslWVKNELIPNLEKEDG*VLICLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYF 710
Cdd:smart00255   1 EYDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78

                           90       100
                   ....*....|....*....|..
gi 1149835609  711 AHHDFFHENSDHIILTLLEPIP 732
Cdd:smart00255  79 ALENALEEGGLRVIPIFYEVIP 100
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
349-522 6.70e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.42  E-value: 6.70e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 349 QYLNFANNILTDDrFKRTIQLPHLKTLILKGYRLErlSLASGFANNTPLKHLDLSQNLLQHKNDENCSWPEtLVTMNLSS 428
Cdd:COG4886   116 ESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLT--DLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN-LKELDLSN 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 429 NKFTD--SVFRCLTrNIPILDLNNNQIQTVSKEIIHLKSLQELNIAFSFLTDLPGCSYFRRLSILNIEMNLIlsPSLDFF 506
Cdd:COG4886   192 NQITDlpEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQL--TDLPPL 268

                         170
                  ....*....|....*.
gi 1149835609 507 QSCQEAKTLNAGKNPF 522
Cdd:COG4886   269 ANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
325-539 1.76e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.80  E-value: 1.76e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 325 DVENLTISNAQIPHM-LFHTYPTRFQYLNFANNILTDdrFKRTI-QLPHLKTLILKGYRLErlSLASGFANNTPLKHLDL 402
Cdd:COG4886   114 NLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTD--LPEPLgNLTNLKSLDLSNNQLT--DLPEELGNLTNLKELDL 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 403 SQNLLQHKNDEnCSWPETLVTMNLSSNKFTD---SVFRCltRNIPILDLNNNQIQTVSkEIIHLKSLQELNIAFSFLTDL 479
Cdd:COG4886   190 SNNQITDLPEP-LGNLTNLEELDLSGNQLTDlpePLANL--TNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDL 265

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 480 PGCSYFRRLSILNIEMNLILSPSLDFFQSCQEAKTLNAGKNPFQCTCELRNFIQLEKYSE 539
Cdd:COG4886   266 PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
56-192 5.41e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.18  E-value: 5.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFNKeLRYLDLSFNRLKIVTW-YSLASLRHLDLSFNDFETMPtg 134
Cdd:COG4886   190 SNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTN-LETLDLSNNQLTDLPElGNLTNLEELDLSNNQLTDLP-- 266

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1149835609 135 eETSNMSFLETLGLSEAKIQKSDFQKIAHLHLNTIFLALRTLSHYEEGSLPILNASIL 192
Cdd:COG4886   267 -PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTL 323
LRR_8 pfam13855
Leucine rich repeat;
71-128 8.09e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 52.53  E-value: 8.09e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1149835609  71 SNLKVLILCHNRIQELNITISEFNKELRYLDLSFNRLKIV---TWYSLASLRHLDLSFNDF 128
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLspgAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
56-247 2.09e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 2.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFnKELRYLDLSFNRLKIVTW--YSLASLRHLDLSFNDFETMPt 133
Cdd:COG4886   167 SNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNL-TNLEELDLSGNQLTDLPEplANLTNLETLDLSNNQLTDLP- 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 134 geETSNMSFLETLGLSEAKIQK----SDFQKIAHLHL--NTI-FLALRTLSHYEEGSLPILNASILHIVHQQM*ISVLLN 206
Cdd:COG4886   245 --ELGNLTNLEELDLSNNQLTDlpplANLTNLKTLDLsnNQLtDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1149835609 207 DRIKTSKILEMTNIDGKSKFVSYEIQQNLILENAKTSTLLL 247
Cdd:COG4886   323 LLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLL 363
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 632-734 3.30e-07

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 50.83  E-value: 3.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 632 FHAFISYS-EHVSLWVKNELIPNLeKEDG*VLiCLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYF 710
Cdd:pfam01582   1 YDVFLSFRgSDTREWFVSHLLKEL-KQKGIKL-FIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVK 78

                          90       100
                  ....*....|....*....|....
gi 1149835609 711 AHHdFFHENSDHIILTLLEPIPFY 734
Cdd:pfam01582  79 ILE-CALDLGQKVIPIFYEVDPSD 101
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
56-153 6.89e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 52.63  E-value: 6.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFnKELRYLDLSFNRLKIVTW--YSLASLRHLDLSFNDFETMPt 133
Cdd:COG4886   121 SGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNL-TNLKSLDLSNNQLTDLPEelGNLTNLKELDLSNNQITDLP- 198

                          90       100
                  ....*....|....*....|
gi 1149835609 134 gEETSNMSFLETLGLSEAKI 153
Cdd:COG4886   199 -EPLGNLTNLEELDLSGNQL 217
LRRCT smart00082
Leucine rich repeat C-terminal domain;
520-572 1.54e-04

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 40.11  E-value: 1.54e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1149835609  520 NPFQCTCELRNFIQLEKYSEgmMVGWSDSYICEYPLNLKGtKLKDIHLPELSC 572
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE--HLQDPVDLRCASPSSLRG-PLLELLHSEFKC 50
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
328-523 3.94e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.77  E-value: 3.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 328 NLTISNAQIPHMLFHTYPTRFQYLNFANNILTDDRFKRTIQLPHLKTLILKGYRLERLSLASGFANNTPLKHLDLSQNLL 407
Cdd:COG4886     5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 408 QHKNDENCSWPETLVTMNLSSNKFTDSVfrcltRNIPILDLNNNQIQTVSKEIIHLKSLQELNIAFSFLTDLP-GCSYFR 486
Cdd:COG4886    85 LLLGLTDLGDLTNLTELDLSGNEELSNL-----TNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPePLGNLT 159

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1149835609 487 RLSILNIEMNLI--LSPSLdffQSCQEAKTLNAGKNPFQ 523
Cdd:COG4886   160 NLKSLDLSNNQLtdLPEEL---GNLTNLKELDLSNNQIT 195
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 635-714 7.15e-04

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 39.99  E-value: 7.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 635 FISYSEHVSLWVKnELIPNLEKEDG*VLicLPERNFDPGKSTGENTISFIEKSCKSIF*LSPDFVQSE*CNHELYFAHHD 714
Cdd:pfam13676   2 FISYAGEDRAWAE-WLADALEAAGYRVW--LDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78
LRR_8 pfam13855
Leucine rich repeat;
370-431 1.84e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1149835609 370 PHLKTLILKGYRLERLSlASGFANNTPLKHLDLSQNLLQHKNDENCSWPETLVTMNLSSNKF 431
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD-DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
58-107 4.21e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 4.21e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1149835609  58 NLLQLQSSDFRSISNLKVLILCHNRIQELNITISEFNKELRYLDLSFNRL 107
Cdd:pfam13855  12 RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
56-154 4.29e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.30  E-value: 4.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609  56 SYNLLQLQSSDFRSISNLKVLILC-----------------HNRIQELNITISEFnKELRYLDLSFNRLKIV--TWYSLA 116
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSgneelsnltnlesldlsGNQLTDLPEELANL-TNLKELDLSNNQLTDLpePLGNLT 159

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1149835609 117 SLRHLDLSFNDFETMPtgEETSNMSFLETLGLSEAKIQ 154
Cdd:COG4886   160 NLKSLDLSNNQLTDLP--EELGNLTNLKELDLSNNQIT 195
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 386-479 8.08e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 39.39  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149835609 386 SLASGFANNTPLKHLDLSQN------------LLQHKNdencswpeTLVTMNLSSNKFTDSVFRCLT------RNIPILD 447
Cdd:COG5238   283 ALAKALQGNTTLTSLDLSVNrigdegaialaeGLQGNK--------TLHTLNLAYNGIGAQGAIALAkalqenTTLHSLD 354

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1149835609 448 LNNNQIQTVS-KEIIHL----KSLQELNIAFSFLTDL 479
Cdd:COG5238   355 LSDNQIGDEGaIALAKYlegnTTLRELNLGKNNIGKQ 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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