|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
522-835 |
8.28e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 8.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 522 CKSKDKEAASYRPLVNEDCLKYGETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNGSEFYYLSELKYLDFSNN 601
Cdd:COG4886 3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 602 RIDLLYSTAFKELKLLEVLDLSYNKHyflaegvthvlnfMKNLTYLKKLMMNENEIsTSISTGMES-QSLQVLEFKGNRL 680
Cdd:COG4886 83 SLLLLGLTDLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQL-TDLPEELANlTNLKELDLSNNQL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 681 DVLWmdgnarylSFFKNLTSLEKLDISFNSLSFLPPGVFEAmpPELRILNLTSNKLKSFSwGKLQLLEKLITLDLSNNLL 760
Cdd:COG4886 149 TDLP--------EPLGNLTNLKSLDLSNNQLTDLPEELGNL--TNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQL 217
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 761 LTVPRELSNCSStIQELILRNNRIQRLTrhFLRGAFNLKYLDLSSNKIQIIKKSSFpenvINNLKMLLLHGNPFK 835
Cdd:COG4886 218 TDLPEPLANLTN-LETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPPLAN----LTNLKTLDLSNNQLT 285
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
172-479 |
8.72e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 87.30 E-value: 8.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 172 ALARLRSLYLDANQLLEIPRGLPTTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNcyyrnpcnvsfeieeTAFLDLK 251
Cdd:COG4886 49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN---------------EELSNLT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 252 NLTILSLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHP 329
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-----------------QLTDLP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 330 KAFQSLKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfqlqmyspslNLS 409
Cdd:COG4886 176 EELGNLTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN----------QLT 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 926488448 410 K--TFSSLVNLEILRLRGyvfkeLKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 479
Cdd:COG4886 242 DlpELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
939-1082 |
2.34e-17 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 79.67 E-value: 2.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 939 CYDAFIAYdnkdpAVNEWVLTELVEKLEDQKVRqFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYMKSGSFKT 1018
Cdd:smart00255 1 EYDVFISY-----SGKEDVRNEFLSHLLEKLRG-YGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLD 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 926488448 1019 TFYMAHQRLIDEKMDVIILIFLEKVLQ--KSRYVRLRKRLcRSSVLEWPTNPRSQpyFWQCLKNAI 1082
Cdd:smart00255 75 ELVAALENALEEGGLRVIPIFYEVIPSdvRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYAV 137
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
166-626 |
2.61e-16 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 84.51 E-value: 2.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 166 ENGSFAalaRLRSLYLDANQLL-EIPRGLP--TTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNcyyrnpcNVSFEI 242
Cdd:PLN00113 159 DIGSFS---SLKVLDLGGNVLVgKIPNSLTnlTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN-------NLSGEI 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 243 eETAFLDLKNLTILSLKSNNLT-YIPPNLS--STLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNcprCYNAPYPCTP 319
Cdd:PLN00113 229 -PYEIGGLTSLNHLDLVYNNLTgPIPSSLGnlKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDN---SLSGEIPELV 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 320 CPKGTIEI-H----------PKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAqflklipsl 388
Cdd:PLN00113 305 IQLQNLEIlHlfsnnftgkiPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEG--------- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 389 veLDLSFN-FQLQMYSPSLN--LSKTFSSLVNLEILRLRGYVFK-ELKQEnldpllhlrnltvldlgtnfikvadlkvFK 464
Cdd:PLN00113 376 --LCSSGNlFKLILFSNSLEgeIPKSLGACRSLRRVRLQDNSFSgELPSE----------------------------FT 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 465 KFPALKFIDLSVNKISpssgesncyrfcpnPRNSVEQYNRQILQDMHYFRYDEYGRSCKSKDKEAAsyrplvnedclkyg 544
Cdd:PLN00113 426 KLPLVYFLDISNNNLQ--------------GRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRL-------------- 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 545 ETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNgSEFYYLSELKYLDFSNNRIDLLYSTAFKELKLLEVLDLSY 624
Cdd:PLN00113 478 ENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIP-DELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQ 556
|
..
gi 926488448 625 NK 626
Cdd:PLN00113 557 NQ 558
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
237-760 |
3.04e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 77.58 E-value: 3.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 237 NVSFEIEETAFLDLKNLTILSLKSNNLT-YIPPNLSSTLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCPrcynapy 315
Cdd:PLN00113 104 QLSGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVL------- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 316 pctpcpKGTIeihPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIgDAQFLKLIpSLVELDLSF 395
Cdd:PLN00113 177 ------VGKI---PNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEI-PYEIGGLT-SLNHLDLVY 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 396 NfqlqmyspslNLSKTF-SSLVNLEILRlrgYVFkeLKQENL-----DPLLHLRNLTVLDLGTNF---------IKVADL 460
Cdd:PLN00113 246 N----------NLTGPIpSSLGNLKNLQ---YLF--LYQNKLsgpipPSIFSLQKLISLDLSDNSlsgeipelvIQLQNL 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 461 KVFKKF---------------PALKFIDLSVNKISpssGESncyrfcpnPRNSVEQYNRQILqdmhyfrydeygrscksk 525
Cdd:PLN00113 311 EILHLFsnnftgkipvaltslPRLQVLQLWSNKFS---GEI--------PKNLGKHNNLTVL------------------ 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 526 DKEAASYRPLVNEDCLKYGE--TLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNgSEFYYLSELKYLDFSNNRI 603
Cdd:PLN00113 362 DLSTNNLTGEIPEGLCSSGNlfKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELP-SEFTKLPLVYFLDISNNNL 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 604 DLLYSTAFKELKLLEVLDLSYNKhyFLAEgvthvLNFMKNLTYLKKLMMNENEISTSISTGMESQS-LQVLEFKGNRLDV 682
Cdd:PLN00113 441 QGRINSRKWDMPSLQMLSLARNK--FFGG-----LPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSeLMQLKLSENKLSG 513
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 926488448 683 LWMDgnarYLSFFKNLTSlekLDISFNSLSFLPPGVFEAMPPeLRILNLTSNKLKSFSWGKLQLLEKLITLDLSNNLL 760
Cdd:PLN00113 514 EIPD----ELSSCKKLVS---LDLSHNQLSGQIPASFSEMPV-LSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
940-1065 |
1.17e-10 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 61.23 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 940 YDAFIAYDNKDpaVNEWVLTELVEKLedqKVRQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYMKSGSFKTT 1019
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKEL---KQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDE 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 1020 FYMAHQRLIDEKMdVIILIFLEKVLQKSR---------YVRLRKRLCRSSVLEWP 1065
Cdd:pfam01582 76 LVKILECALDLGQ-KVIPIFYEVDPSDVRkqtgsfgkaFKKHKKVLTEEKVLKWR 129
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
250-450 |
2.75e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.34 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 250 LKNLTILSLKSNNLTYIpPNLSST--LKELYIYNNMIQVIQehDLIALHNLEILDLSGNCPRCynapypctpcpkgtIEi 327
Cdd:cd21340 1 LKRITHLYLNDKNITKI-DNLSLCknLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--------------IE- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 328 hpkAFQSLKQLKILRLHSNSLQRIlsSWFENTRNLKELDLSQNFLAKE---IGDAQFLKLI-PSLVELDLSFNfQLQMYS 403
Cdd:cd21340 63 ---NLENLVNLKKLYLGGNRISVV--EGLENLTNLEELHIENQRLPPGeklTFDPRSLAALsNSLRVLNISGN-NIDSLE 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 926488448 404 PslnlsktFSSLVNLEILRLRGYVFKELKqENLDPLLHLRNLTVLDL 450
Cdd:cd21340 137 P-------LAPLRNLEQLDASNNQISDLE-ELLDLLSSWPSLRELDL 175
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
802-889 |
7.36e-09 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 60.48 E-value: 7.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 802 DLSSNKIQIIKKSSFpeNVINNLKMLLLHGNPFKCNCDAVWFVWWINQTQVTIpLLATDVTCAGPGAHKGKSVVFLDLYT 881
Cdd:TIGR00864 1 DISNNKISTIEEGIC--ANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKV-RQPEAALCAGPGALAGQPLLGIPLLD 77
|
....*...
gi 926488448 882 CELDTSYL 889
Cdd:TIGR00864 78 SGCDEEYV 85
|
|
| LRR_12 |
pfam18837 |
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the ... |
445-474 |
3.18e-08 |
|
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the pfam00560 model. This entry represents one repeat unit.
Pssm-ID: 408607 Cd Length: 30 Bit Score: 50.42 E-value: 3.18e-08
10 20 30
....*....|....*....|....*....|
gi 926488448 445 LTVLDLGTNFIKVADLKVFKKFPALKFIDL 474
Cdd:pfam18837 1 LQTLHLQMNFINQAQLSIFGAFPGLRFVDL 30
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
545-603 |
5.94e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.52 E-value: 5.94e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 545 ETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISqTLNGSEFYYLSELKYLDFSNNRI 603
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT-TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
57-207 |
1.66e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.92 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 57 KIPNALPYVL--LFVFPKLLSGVwfPKSLPCDVEvskatvTVDCSDRRLTEIPRGIPTNATNLTLTINHIPHVYPTSFAH 134
Cdd:PRK15370 255 ELPERLPSALqsLDLFHNKISCL--PENLPEELR------YLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPG 326
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 926488448 135 LENLMEIDFRCNCVPVRLGPKDHVCTrtpqIENGSFAALAR-----LRSLYLDANQLLEIPRGLPTTLRLLSLEANSI 207
Cdd:PRK15370 327 LKTLEAGENALTSLPASLPPELQVLD----VSKNQITVLPEtlpptITTLDVSRNALTNLPENLPAALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
112-186 |
1.74e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 1.74e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 112 TNATNLTLTINHIPHVYPTSFAHLENLMEIDFRCNCVPVrlgpkdhvctrtpqIENGSFAALARLRSLYLDANQL 186
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--------------LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
544-808 |
3.44e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 47.35 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 544 GETLDLSRNNIFFISPSDFQDLGfLRCLNLSGNAISQTlnGSEFYYLSELKYLDFS-NNRIDLLYST-----AFKELKLL 617
Cdd:cd00116 7 GELLKTERATELLPKLLCLQVLR-LEGNTLGEEAAKAL--ASALRPQPSLKELCLSlNETGRIPRGLqsllqGLTKGCGL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 618 EVLDLSYNkhYFLAEGVTHVLNFMKNLTyLKKLMMNENEISTSI------STGMESQSLQVLEFKGNRLDVlwmDGNARY 691
Cdd:cd00116 84 QELDLSDN--ALGPDGCGVLESLLRSSS-LQELKLNNNGLGDRGlrllakGLKDLPPALEKLVLGRNRLEG---ASCEAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 692 LSFFKNLTSLEKLDISFNSLsfLPPGV---FEAMP--PELRILNLTSNKLK----SFSWGKLQLLEKLITLDLSNNLLlt 762
Cdd:cd00116 158 AKALRANRDLKELNLANNGI--GDAGIralAEGLKanCNLEVLDLNNNGLTdegaSALAETLASLKSLEVLNLGDNNL-- 233
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 926488448 763 vprelsncsstiqelilRNNRIQRLTRHFLRGAFNLKYLDLSSNKI 808
Cdd:cd00116 234 -----------------TDAGAAALASALLSPNISLLTLSLSCNDI 262
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
832-878 |
6.90e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 38.57 E-value: 6.90e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 926488448 832 NPFKCNCDAVWFVWWINQTQVTipLLATDVTCAGPGAHKGKSVVFLD 878
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHL--QDPVDLRCASPSSLRGPLLELLH 45
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
95-116 |
5.89e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 5.89e-03
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
698-720 |
8.47e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.47e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
522-835 |
8.28e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 8.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 522 CKSKDKEAASYRPLVNEDCLKYGETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNGSEFYYLSELKYLDFSNN 601
Cdd:COG4886 3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 602 RIDLLYSTAFKELKLLEVLDLSYNKHyflaegvthvlnfMKNLTYLKKLMMNENEIsTSISTGMES-QSLQVLEFKGNRL 680
Cdd:COG4886 83 SLLLLGLTDLGDLTNLTELDLSGNEE-------------LSNLTNLESLDLSGNQL-TDLPEELANlTNLKELDLSNNQL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 681 DVLWmdgnarylSFFKNLTSLEKLDISFNSLSFLPPGVFEAmpPELRILNLTSNKLKSFSwGKLQLLEKLITLDLSNNLL 760
Cdd:COG4886 149 TDLP--------EPLGNLTNLKSLDLSNNQLTDLPEELGNL--TNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQL 217
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 761 LTVPRELSNCSStIQELILRNNRIQRLTrhFLRGAFNLKYLDLSSNKIQIIKKSSFpenvINNLKMLLLHGNPFK 835
Cdd:COG4886 218 TDLPEPLANLTN-LETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPPLAN----LTNLKTLDLSNNQLT 285
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
541-860 |
2.98e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 88.45 E-value: 2.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 541 LKYGETLDLSRNNIFFIsPSDFQDLGFLRCLNLSGNAISQTlnGSEFYYLSELKYLDFSNNRIDLLySTAFKELKLLEVL 620
Cdd:COG4886 112 LTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDL--PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKEL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 621 DLSYNKhyflaegVTHVLNFMKNLTYLKKLMMNENEIsTSISTGMES-QSLQVLEFKGNRLdvlwmdgnaRYLSFFKNLT 699
Cdd:COG4886 188 DLSNNQ-------ITDLPEPLGNLTNLEELDLSGNQL-TDLPEPLANlTNLETLDLSNNQL---------TDLPELGNLT 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 700 SLEKLDISFNSLSFLPPgvfEAMPPELRILNLTSNKLKSFSWGKLQLLEKLITLDLSNNLLLTVPRELS-NCSSTIQELI 778
Cdd:COG4886 251 NLEELDLSNNQLTDLPP---LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILlLLLTTLLLLL 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 779 LRNNRIQRLTRHFLRGAFNLKYLDLSSNKIQIIKKSSFPENVINNLKMLLLHGNPFKCNCDAVWFVWWINQTQVTIPLLA 858
Cdd:COG4886 328 LLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLAL 407
|
..
gi 926488448 859 TD 860
Cdd:COG4886 408 LD 409
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
172-479 |
8.72e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 87.30 E-value: 8.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 172 ALARLRSLYLDANQLLEIPRGLPTTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNcyyrnpcnvsfeieeTAFLDLK 251
Cdd:COG4886 49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN---------------EELSNLT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 252 NLTILSLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHP 329
Cdd:COG4886 114 NLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNN-----------------QLTDLP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 330 KAFQSLKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfqlqmyspslNLS 409
Cdd:COG4886 176 EELGNLTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQL-TDLPEP--LANLTNLETLDLSNN----------QLT 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 926488448 410 K--TFSSLVNLEILRLRGyvfkeLKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 479
Cdd:COG4886 242 DlpELGNLTNLEELDLSN-----NQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
939-1082 |
2.34e-17 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 79.67 E-value: 2.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 939 CYDAFIAYdnkdpAVNEWVLTELVEKLEDQKVRqFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYMKSGSFKT 1018
Cdd:smart00255 1 EYDVFISY-----SGKEDVRNEFLSHLLEKLRG-YGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLD 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 926488448 1019 TFYMAHQRLIDEKMDVIILIFLEKVLQ--KSRYVRLRKRLcRSSVLEWPTNPRSQpyFWQCLKNAI 1082
Cdd:smart00255 75 ELVAALENALEEGGLRVIPIFYEVIPSdvRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYAV 137
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
173-479 |
8.56e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.21 E-value: 8.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 173 LARLRSLYLDANQLLEIPRGLPTTLRLLSLEANSifsitraNLSELRNIEVLYLGQNCYYRNPCNVSfeieetaflDLKN 252
Cdd:COG4886 74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELA---------NLTN 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 253 LTILSLKSNNLTYIPPNLSS--TLKELYIYNNMIQVIQEHdLIALHNLEILDLSGNCprcynapypctpcpkgtIEIHPK 330
Cdd:COG4886 138 LKELDLSNNQLTDLPEPLGNltNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ-----------------ITDLPE 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 331 AFQSLKQLKILRLHSNSLQRiLSSWFENTRNLKELDLSQNflakEIGDAQFLKLIPSLVELDLSFNfQLQMYSPSLNLSk 410
Cdd:COG4886 200 PLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNN----QLTDLPELGNLTNLEELDLSNN-QLTDLPPLANLT- 272
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 411 tfsslvNLEILRLRGYVFKELKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKI 479
Cdd:COG4886 273 ------NLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLV 335
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
176-480 |
1.06e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.83 E-value: 1.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 176 LRSLYLDANQLLEIPRGLPTTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNCYYRNPCNVSFEIEETAFLDLKNLTI 255
Cdd:COG4886 21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 256 LSLKSNNLTYIPPNlsstLKELYIYNNMIQVIqEHDLIALHNLEILDLSGNcprcynapypctpcpkgTIEIHPKAFQSL 335
Cdd:COG4886 101 LDLSGNEELSNLTN----LESLDLSGNQLTDL-PEELANLTNLKELDLSNN-----------------QLTDLPEPLGNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 336 KQLKILRLHSNSLQRIlSSWFENTRNLKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfQLQmyspslNLSKTFSSL 415
Cdd:COG4886 159 TNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI-TDLPEP--LGNLTNLEELDLSGN-QLT------DLPEPLANL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 416 VNLEILRLRGyvfKELkqENLDPLLHLRNLTVLDLGTNFIKvaDLKVFKKFPALKFIDLSVNKIS 480
Cdd:COG4886 228 TNLETLDLSN---NQL--TDLPELGNLTNLEELDLSNNQLT--DLPPLANLTNLKTLDLSNNQLT 285
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
166-477 |
2.12e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.06 E-value: 2.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 166 ENGSFAALARLRSLYLDANQLLEIPrglpttlrllsleansifsitrANLSELRNIEVLYLGQNcyyrnpcnvSFEIEET 245
Cdd:COG4886 105 GNEELSNLTNLESLDLSGNQLTDLP----------------------EELANLTNLKELDLSNN---------QLTDLPE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 246 AFLDLKNLTILSLKSNNLTYIPPNLS--STLKELYIYNNMIQVIQEhDLIALHNLEILDLSGNcprcynapypctpcpkg 323
Cdd:COG4886 154 PLGNLTNLKSLDLSNNQLTDLPEELGnlTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGN----------------- 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 324 TIEIHPKAFQSLKQLKILRLHSNSLQRIlsSWFENTRNLKELDLSQNflakEIGDAQFLKLIPSLVELDLSFNFQLQMYS 403
Cdd:COG4886 216 QLTDLPEPLANLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNN----QLTDLPPLANLTNLKTLDLSNNQLTDLKL 289
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 404 PSL-NLSKTFSSLVNLEILRLRGYVFKELKQENLDPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVN 477
Cdd:COG4886 290 KELeLLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
166-626 |
2.61e-16 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 84.51 E-value: 2.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 166 ENGSFAalaRLRSLYLDANQLL-EIPRGLP--TTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNcyyrnpcNVSFEI 242
Cdd:PLN00113 159 DIGSFS---SLKVLDLGGNVLVgKIPNSLTnlTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN-------NLSGEI 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 243 eETAFLDLKNLTILSLKSNNLT-YIPPNLS--STLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNcprCYNAPYPCTP 319
Cdd:PLN00113 229 -PYEIGGLTSLNHLDLVYNNLTgPIPSSLGnlKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDN---SLSGEIPELV 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 320 CPKGTIEI-H----------PKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAqflklipsl 388
Cdd:PLN00113 305 IQLQNLEIlHlfsnnftgkiPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEG--------- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 389 veLDLSFN-FQLQMYSPSLN--LSKTFSSLVNLEILRLRGYVFK-ELKQEnldpllhlrnltvldlgtnfikvadlkvFK 464
Cdd:PLN00113 376 --LCSSGNlFKLILFSNSLEgeIPKSLGACRSLRRVRLQDNSFSgELPSE----------------------------FT 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 465 KFPALKFIDLSVNKISpssgesncyrfcpnPRNSVEQYNRQILQDMHYFRYDEYGRSCKSKDKEAAsyrplvnedclkyg 544
Cdd:PLN00113 426 KLPLVYFLDISNNNLQ--------------GRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRL-------------- 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 545 ETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNgSEFYYLSELKYLDFSNNRIDLLYSTAFKELKLLEVLDLSY 624
Cdd:PLN00113 478 ENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIP-DELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQ 556
|
..
gi 926488448 625 NK 626
Cdd:PLN00113 557 NQ 558
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
237-760 |
3.04e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 77.58 E-value: 3.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 237 NVSFEIEETAFLDLKNLTILSLKSNNLT-YIPPNLSSTLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCPrcynapy 315
Cdd:PLN00113 104 QLSGPIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVL------- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 316 pctpcpKGTIeihPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIgDAQFLKLIpSLVELDLSF 395
Cdd:PLN00113 177 ------VGKI---PNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEI-PYEIGGLT-SLNHLDLVY 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 396 NfqlqmyspslNLSKTF-SSLVNLEILRlrgYVFkeLKQENL-----DPLLHLRNLTVLDLGTNF---------IKVADL 460
Cdd:PLN00113 246 N----------NLTGPIpSSLGNLKNLQ---YLF--LYQNKLsgpipPSIFSLQKLISLDLSDNSlsgeipelvIQLQNL 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 461 KVFKKF---------------PALKFIDLSVNKISpssGESncyrfcpnPRNSVEQYNRQILqdmhyfrydeygrscksk 525
Cdd:PLN00113 311 EILHLFsnnftgkipvaltslPRLQVLQLWSNKFS---GEI--------PKNLGKHNNLTVL------------------ 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 526 DKEAASYRPLVNEDCLKYGE--TLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLNgSEFYYLSELKYLDFSNNRI 603
Cdd:PLN00113 362 DLSTNNLTGEIPEGLCSSGNlfKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELP-SEFTKLPLVYFLDISNNNL 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 604 DLLYSTAFKELKLLEVLDLSYNKhyFLAEgvthvLNFMKNLTYLKKLMMNENEISTSISTGMESQS-LQVLEFKGNRLDV 682
Cdd:PLN00113 441 QGRINSRKWDMPSLQMLSLARNK--FFGG-----LPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSeLMQLKLSENKLSG 513
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 926488448 683 LWMDgnarYLSFFKNLTSlekLDISFNSLSFLPPGVFEAMPPeLRILNLTSNKLKSFSWGKLQLLEKLITLDLSNNLL 760
Cdd:PLN00113 514 EIPD----ELSSCKKLVS---LDLSHNQLSGQIPASFSEMPV-LSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
106-480 |
6.38e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 76.43 E-value: 6.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 106 IPRGIPTNATNLTLTINHIPHVYPTSFAHLENLMEIDFRCNC----VPVRLG--PKDHVCT-RTPQIENGSFAALARLRS 178
Cdd:PLN00113 134 IPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVlvgkIPNSLTnlTSLEFLTlASNQLVGQIPRELGQMKS 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 179 L---YLDANQLL-EIPR--GLPTTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNCYYRNPCNVSFEIEETAFLD--- 249
Cdd:PLN00113 214 LkwiYLGYNNLSgEIPYeiGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDlsd 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 250 -------------LKNLTILSLKSNNLT-YIPPNLSS--TLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCprcYNA 313
Cdd:PLN00113 294 nslsgeipelviqLQNLEILHLFSNNFTgKIPVALTSlpRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN---LTG 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 314 PYPCTPCPKGTI------------EIhPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAQF 381
Cdd:PLN00113 371 EIPEGLCSSGNLfklilfsnslegEI-PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKW 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 382 LklIPSLVELDLS---FNFQLQMYSPSLNLSK--------------TFSSLVNLEILRLRGyvfKELKQENLDPLLHLRN 444
Cdd:PLN00113 450 D--MPSLQMLSLArnkFFGGLPDSFGSKRLENldlsrnqfsgavprKLGSLSELMQLKLSE---NKLSGEIPDELSSCKK 524
|
410 420 430
....*....|....*....|....*....|....*.
gi 926488448 445 LTVLDLGTNFIKVADLKVFKKFPALKFIDLSVNKIS 480
Cdd:PLN00113 525 LVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLS 560
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
202-480 |
2.18e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 70.35 E-value: 2.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 202 LEANSIFSITRANLSELRNIEVLYLGQNCYYRNPCNVSFEIEETAFLDLKNLTILSLKSNNLTYIPPNLSSTLKELYIYN 281
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 282 NMIQVIQEHDLIALHNLEILDLSGNCPRCYNAPYPCTPCPKGTIEIHPKAFQSLKQLKILRLHSNSLQRILSSWFENTrN 361
Cdd:COG4886 82 LSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT-N 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 362 LKELDLSQNFLaKEIGDAqfLKLIPSLVELDLSFNfQLQmyspslNLSKTFSSLVNLEILRLRGYVFKELKqenlDPLLH 441
Cdd:COG4886 161 LKSLDLSNNQL-TDLPEE--LGNLTNLKELDLSNN-QIT------DLPEPLGNLTNLEELDLSGNQLTDLP----EPLAN 226
|
250 260 270
....*....|....*....|....*....|....*....
gi 926488448 442 LRNLTVLDLGTNfiKVADLKVFKKFPALKFIDLSVNKIS 480
Cdd:COG4886 227 LTNLETLDLSNN--QLTDLPELGNLTNLEELDLSNNQLT 263
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
546-832 |
5.37e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 67.18 E-value: 5.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 546 TLDLSRNNIFF-ISPSDFQdLGFLRCLNLSGNAISQTLNGSEFYYLSELKYLDFSNNRIDLLYSTAFkeLKLLEVLDLSY 624
Cdd:PLN00113 73 SIDLSGKNISGkISSAIFR-LPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLSNNNFTGSIPRGS--IPNLETLDLSN 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 625 N--------------KHYFLAEG----VTHVLNFMKNLTYLKKLMMNENEISTSISTGM-ESQSLQVLEFKGNRLdvlwm 685
Cdd:PLN00113 150 NmlsgeipndigsfsSLKVLDLGgnvlVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELgQMKSLKWIYLGYNNL----- 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 686 DGNARYLsfFKNLTSLEKLDISFNSLSFLPPGVFEAMpPELRILNLTSNKLKSFSWGKLQLLEKLITLDLSNNLLltvpr 765
Cdd:PLN00113 225 SGEIPYE--IGGLTSLNHLDLVYNNLTGPIPSSLGNL-KNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSL----- 296
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 766 elsncSSTIQELI--LRNNRIQRLTRHFLRGAF--------NLKYLDLSSNKIQiikkSSFPENV--INNLKMLLLHGN 832
Cdd:PLN00113 297 -----SGEIPELViqLQNLEILHLFSNNFTGKIpvaltslpRLQVLQLWSNKFS----GEIPKNLgkHNNLTVLDLSTN 366
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
940-1065 |
1.17e-10 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 61.23 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 940 YDAFIAYDNKDpaVNEWVLTELVEKLedqKVRQFNLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYMKSGSFKTT 1019
Cdd:pfam01582 1 YDVFLSFRGSD--TREWFVSHLLKEL---KQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDE 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 1020 FYMAHQRLIDEKMdVIILIFLEKVLQKSR---------YVRLRKRLCRSSVLEWP 1065
Cdd:pfam01582 76 LVKILECALDLGQ-KVIPIFYEVDPSDVRkqtgsfgkaFKKHKKVLTEEKVLKWR 129
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
112-306 |
2.51e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 63.80 E-value: 2.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 112 TNATNLTLTINHIPHVyPTSFAHLENLMEIDFRCNcvpvrlgpkdhvctrtpQIEN--GSFAALARLRSLYLDANQLLEI 189
Cdd:COG4886 113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNN-----------------QLTDlpEPLGNLTNLKSLDLSNNQLTDL 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 190 PRGLP--TTLRLLSLEANSIFSITRAnLSELRNIEVLYLGQNCYYRNPCNVSfeieetaflDLKNLTILSLKSNNLTYIP 267
Cdd:COG4886 175 PEELGnlTNLKELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEPLA---------NLTNLETLDLSNNQLTDLP 244
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 926488448 268 P--NLSStLKELYIYNNMIQVIQEhdLIALHNLEILDLSGN 306
Cdd:COG4886 245 ElgNLTN-LEELDLSNNQLTDLPP--LANLTNLKTLDLSNN 282
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
250-450 |
2.75e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 61.34 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 250 LKNLTILSLKSNNLTYIpPNLSST--LKELYIYNNMIQVIQehDLIALHNLEILDLSGNCPRCynapypctpcpkgtIEi 327
Cdd:cd21340 1 LKRITHLYLNDKNITKI-DNLSLCknLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEK--------------IE- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 328 hpkAFQSLKQLKILRLHSNSLQRIlsSWFENTRNLKELDLSQNFLAKE---IGDAQFLKLI-PSLVELDLSFNfQLQMYS 403
Cdd:cd21340 63 ---NLENLVNLKKLYLGGNRISVV--EGLENLTNLEELHIENQRLPPGeklTFDPRSLAALsNSLRVLNISGN-NIDSLE 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 926488448 404 PslnlsktFSSLVNLEILRLRGYVFKELKqENLDPLLHLRNLTVLDL 450
Cdd:cd21340 137 P-------LAPLRNLEQLDASNNQISDLE-ELLDLLSSWPSLRELDL 175
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
802-889 |
7.36e-09 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 60.48 E-value: 7.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 802 DLSSNKIQIIKKSSFpeNVINNLKMLLLHGNPFKCNCDAVWFVWWINQTQVTIpLLATDVTCAGPGAHKGKSVVFLDLYT 881
Cdd:TIGR00864 1 DISNNKISTIEEGIC--ANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKV-RQPEAALCAGPGALAGQPLLGIPLLD 77
|
....*...
gi 926488448 882 CELDTSYL 889
Cdd:TIGR00864 78 SGCDEEYV 85
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
200-396 |
7.67e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 57.10 E-value: 7.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 200 LSLEANSIFSITraNLSELRNIEVLYLgqncyYRNpcnvsfEIEETAFLD-LKNLTILSLKSNNLTYIpPNLSS--TLKE 276
Cdd:cd21340 7 LYLNDKNITKID--NLSLCKNLKVLYL-----YDN------KITKIENLEfLTNLTHLYLQNNQIEKI-ENLENlvNLKK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 277 LYIYNNMIQVIQehDLIALHNLEILDLSGNCPrcynapypctpcPKG-TIEIHPKAFQSL-KQLKILRLHSNSLQRIlsS 354
Cdd:cd21340 73 LYLGGNRISVVE--GLENLTNLEELHIENQRL------------PPGeKLTFDPRSLAALsNSLRVLNISGNNIDSL--E 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 926488448 355 WFENTRNLKELDLSQNFLA--KEIgdAQFLKLIPSLVELDLSFN 396
Cdd:cd21340 137 PLAPLRNLEQLDASNNQISdlEEL--LDLLSSWPSLRELDLTGN 178
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
81-299 |
2.74e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 58.17 E-value: 2.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 81 KSLPCDVEVSKATVTVDcsDRRLTEIPRGIPTNATNLTLTINHI---PHVYPTSfahlenLMEIDFRCN---CVPVRLgP 154
Cdd:PRK15370 212 KSLPENLQGNIKTLYAN--SNQLTSIPATLPDTIQEMELSINRItelPERLPSA------LQSLDLFHNkisCLPENL-P 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 155 KDhvctrtpqiengsfaalarLRSLYLDANQLLEIPRGLPTTLRLLSLEANSIFSITrANLSElrNIEVLYLGQNCYYRN 234
Cdd:PRK15370 283 EE-------------------LRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALP-ETLPP--GLKTLEAGENALTSL 340
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 235 PCNVSFEieetafldlknLTILSLKSNNLTYIPPNLSSTLKELYIYNNMIQVIQEHDLIALHNLE 299
Cdd:PRK15370 341 PASLPPE-----------LQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLPENLPAALQIMQ 394
|
|
| LRR_12 |
pfam18837 |
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the ... |
445-474 |
3.18e-08 |
|
Leucine-rich repeat; This Pfam entry includes some LRRs that fail to be detected with the pfam00560 model. This entry represents one repeat unit.
Pssm-ID: 408607 Cd Length: 30 Bit Score: 50.42 E-value: 3.18e-08
10 20 30
....*....|....*....|....*....|
gi 926488448 445 LTVLDLGTNFIKVADLKVFKKFPALKFIDL 474
Cdd:pfam18837 1 LQTLHLQMNFINQAQLSIFGAFPGLRFVDL 30
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
174-372 |
5.94e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 57.01 E-value: 5.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 174 ARLRSLYLDANQLLEIPRGLPTTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNCYyrnPCNVSFEieetafldlknL 253
Cdd:PRK15370 220 GNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCL---PENLPEE-----------L 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 254 TILSLKSNNLTYIPPNLSSTLKELYIYNNMIQVIQEhdlIALHNLEILDLSGNCPRCYNAPYPctpcpkgtieihpkafq 333
Cdd:PRK15370 286 RYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLPASLP----------------- 345
|
170 180 190
....*....|....*....|....*....|....*....
gi 926488448 334 slKQLKILRLHSNSLQrILSSWFENTrnLKELDLSQNFL 372
Cdd:PRK15370 346 --PELQVLDVSKNQIT-VLPETLPPT--ITTLDVSRNAL 379
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
176-315 |
7.62e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 54.41 E-value: 7.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 176 LRSLYLDANQLLEIPrGLPTTLRL--LSLEANSIFSITraNLSELRNIEVLYLGQNC-------------------YYRN 234
Cdd:cd21340 26 LKVLYLYDNKITKIE-NLEFLTNLthLYLQNNQIEKIE--NLENLVNLKKLYLGGNRisvveglenltnleelhieNQRL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 235 PCNVSFEIEETAFLDL-KNLTILSLKSNNLTYIPP--NLSStLKELYIYNNMIQVIQE--HDLIALHNLEILDLSGNcPR 309
Cdd:cd21340 103 PPGEKLTFDPRSLAALsNSLRVLNISGNNIDSLEPlaPLRN-LEQLDASNNQISDLEEllDLLSSWPSLRELDLTGN-PV 180
|
....*.
gi 926488448 310 CYNAPY 315
Cdd:cd21340 181 CKKPKY 186
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
943-1041 |
3.15e-07 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 50.01 E-value: 3.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 943 FIAYDNKDpavNEWVLtELVEKLEDQKVRqfnLCLEERDWLPGQPVFDNLSQSIQLSKKTIFVLTNKYMKSGSFKTTFYM 1022
Cdd:pfam13676 2 FISYAGED---RAWAE-WLADALEAAGYR---VWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEA 74
|
90
....*....|....*....
gi 926488448 1023 AHQRLIDEKmdVIILIFLE 1041
Cdd:pfam13676 75 ALADPEGRK--RLIPVRLE 91
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
545-603 |
5.94e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.52 E-value: 5.94e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 545 ETLDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISqTLNGSEFYYLSELKYLDFSNNRI 603
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT-TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
568-626 |
9.23e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 9.23e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 568 LRCLNLSGNAIsQTLNGSEFYYLSELKYLDFSNNRIDLLYSTAFKELKLLEVLDLSYNK 626
Cdd:pfam13855 3 LRSLDLSNNRL-TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
337-396 |
1.23e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 1.23e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 337 QLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLaKEIGDAQFLKLiPSLVELDLSFN 396
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL-TTLSPGAFSGL-PSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
772-834 |
2.28e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 2.28e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 926488448 772 STIQELILRNNRIQRLTRHFLRGAFNLKYLDLSSNKIQIIKKSSFPEnvINNLKMLLLHGNPF 834
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG--LPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
252-306 |
2.66e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 2.66e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 252 NLTILSLKSNNLTYIPP----NLSStLKELYIYNNMIQVIQEHDLIALHNLEILDLSGN 306
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDgafkGLSN-LKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
617-828 |
2.72e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 51.62 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 617 LEVLDLSYNKHYFLAEGVTHVL--NFMKNL-----TYLKKLMMNENEIsTSISTGMeSQSLQVLEFKGNR---------- 679
Cdd:PRK15370 185 LKILGLTTIPACIPEQITTLILdnNELKSLpenlqGNIKTLYANSNQL-TSIPATL-PDTIQEMELSINRitelperlps 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 680 -LDVLWMDGNA------------RYLSFFKN-LTSLEK--------LDISFNSLSFLP----PGVF-------------E 720
Cdd:PRK15370 263 aLQSLDLFHNKisclpenlpeelRYLSVYDNsIRTLPAhlpsgithLNVQSNSLTALPetlpPGLKtleagenaltslpA 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 721 AMPPELRILNLTSNKLKSFSwgkLQLLEKLITLDLSNNLLLTVPRelsNCSSTIQELILRNNRIQRLTR---HFL-RGAf 796
Cdd:PRK15370 343 SLPPELQVLDVSKNQITVLP---ETLPPTITTLDVSRNALTNLPE---NLPAALQIMQASRNNLVRLPEslpHFRgEGP- 415
|
250 260 270
....*....|....*....|....*....|..
gi 926488448 797 nlkyldlSSNKIqIIKKSSFPENVINNLKMLL 828
Cdd:PRK15370 416 -------QPTRI-IVEYNPFSERTIQNMQRLM 439
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
110-420 |
3.43e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 51.39 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 110 IPTNATNLT------LTINHIPHVYPTSFAHLENLMEIDFRCNCVPVRLgpkdhvctrtPQIengsFAALARLRSLYLDA 183
Cdd:PLN00113 252 IPSSLGNLKnlqylfLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEI----------PEL----VIQLQNLEILHLFS 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 184 NQLL-EIPRGLPTTLRL--LSLEANSIFSITRANLSELRNIEVLYLGQNcyyrnpcNVSFEIEETaFLDLKNLTILSLKS 260
Cdd:PLN00113 318 NNFTgKIPVALTSLPRLqvLQLWSNKFSGEIPKNLGKHNNLTVLDLSTN-------NLTGEIPEG-LCSSGNLFKLILFS 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 261 NNL-TYIPPNLS--STLKELYIYNNMIQVIQEHDLIALHNLEILDLSGN------CPRCYNAP------------YPCTP 319
Cdd:PLN00113 390 NSLeGEIPKSLGacRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNnlqgriNSRKWDMPslqmlslarnkfFGGLP 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 320 CPKGTIEIH-------------PKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAqfLKLIP 386
Cdd:PLN00113 470 DSFGSKRLEnldlsrnqfsgavPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPAS--FSEMP 547
|
330 340 350
....*....|....*....|....*....|....
gi 926488448 387 SLVELDLSFNfQLQMYSPSlNLSKTfSSLVNLEI 420
Cdd:PLN00113 548 VLSQLDLSQN-QLSGEIPK-NLGNV-ESLVQVNI 578
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
668-736 |
9.35e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 9.35e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 668 QSLQVLEFKGNRLDVLWMDgnarylsFFKNLTSLEKLDISFNSLSFLPPGVFEAMpPELRILNLTSNKL 736
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDG-------AFKGLSNLKVLDLSNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
568-787 |
9.89e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 49.40 E-value: 9.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 568 LRCLNLSGNAIsqTLNGSEFY--YLSELK---YLDFSNNRID----LLYSTAFKELKLLEVLDLSYNkhYFLAEGVTHVL 638
Cdd:COG5238 210 VTTLWLKRNPI--GDEGAEILaeALKGNKsltTLDLSNNQIGdegvIALAEALKNNTTVETLYLSGN--QIGAEGAIALA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 639 NFMKNLTYLKKLMMNENEIS----TSISTGME-SQSLQVLEFKGNRLDVLWMDGNARYLsffKNLTSLEKLDISFNSLSf 713
Cdd:COG5238 286 KALQGNTTLTSLDLSVNRIGdegaIALAEGLQgNKTLHTLNLAYNGIGAQGAIALAKAL---QENTTLHSLDLSDNQIG- 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 714 lPPGV-----FEAMPPELRILNLTSNKLKSFswGKLQLLE-----KLITLDLSNNLLLTVPRELsncsstIQELIlrnNR 783
Cdd:COG5238 362 -DEGAialakYLEGNTTLRELNLGKNNIGKQ--GAEALIDalqtnRLHTLILDGNLIGAEAQQR------LEQLL---ER 429
|
....
gi 926488448 784 IQRL 787
Cdd:COG5238 430 IKSV 433
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
57-207 |
1.66e-05 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 48.92 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 57 KIPNALPYVL--LFVFPKLLSGVwfPKSLPCDVEvskatvTVDCSDRRLTEIPRGIPTNATNLTLTINHIPHVYPTSFAH 134
Cdd:PRK15370 255 ELPERLPSALqsLDLFHNKISCL--PENLPEELR------YLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPG 326
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 926488448 135 LENLMEIDFRCNCVPVRLGPKDHVCTrtpqIENGSFAALAR-----LRSLYLDANQLLEIPRGLPTTLRLLSLEANSI 207
Cdd:PRK15370 327 LKTLEAGENALTSLPASLPPELQVLD----VSKNQITVLPEtlpptITTLDVSRNALTNLPENLPAALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
112-186 |
1.74e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 1.74e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 926488448 112 TNATNLTLTINHIPHVYPTSFAHLENLMEIDFRCNCVPVrlgpkdhvctrtpqIENGSFAALARLRSLYLDANQL 186
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--------------LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
545-834 |
1.78e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 49.08 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 545 ETLDLSrNNIFfiSPSDFQDLGF---LRCLNLSGNAISQTLNGSeFYYLSELKYLDFSNNR-----------------ID 604
Cdd:PLN00113 143 ETLDLS-NNML--SGEIPNDIGSfssLKVLDLGGNVLVGKIPNS-LTNLTSLEFLTLASNQlvgqiprelgqmkslkwIY 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 605 LLYS-------TAFKELKLLEVLDLSYNKhyfLAEGVTHVLNFMKNLTYlkkLMMNENEISTSISTGMES-QSLQVLEFK 676
Cdd:PLN00113 219 LGYNnlsgeipYEIGGLTSLNHLDLVYNN---LTGPIPSSLGNLKNLQY---LFLYQNKLSGPIPPSIFSlQKLISLDLS 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 677 GNRLdvlwmdgNARYLSFFKNLTSLEKLDISFNSLSFLPPGVFEAMpPELRILNLTSNKLKSFSWGKLQLLEKLITLDLS 756
Cdd:PLN00113 293 DNSL-------SGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSL-PRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLS 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 757 NN------------------LLL-------TVPRELSNCSSTIQELILRNNRIQRLTRHFLRGAFnLKYLDLSSNKIQII 811
Cdd:PLN00113 365 TNnltgeipeglcssgnlfkLILfsnslegEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPL-VYFLDISNNNLQGR 443
|
330 340
....*....|....*....|...
gi 926488448 812 KKSSFPEnvINNLKMLLLHGNPF 834
Cdd:PLN00113 444 INSRKWD--MPSLQMLSLARNKF 464
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
358-808 |
1.89e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 49.08 E-value: 1.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 358 NTRNLKELDLSQNFLAKEIGDAQFLklIPSLVELDLSFNfQLQMYSPSlNLSKTFSSL--VNLEILRLRGYVfkelkqen 435
Cdd:PLN00113 67 NSSRVVSIDLSGKNISGKISSAIFR--LPYIQTINLSNN-QLSGPIPD-DIFTTSSSLryLNLSNNNFTGSI-------- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 436 ldPLLHLRNLTVLDLGTNFIKVADLKVFKKFPALKFIDLSVN----KISPSSGESNCYRFCPNPRNsveQYNRQI---LQ 508
Cdd:PLN00113 135 --PRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNvlvgKIPNSLTNLTSLEFLTLASN---QLVGQIpreLG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 509 DMHYFRYDEYGrsckskdkeaasYRPLVNEDCLKYGET-----LDLSRNNIFFISPSDFQDLGFLRCLNLSGNAISQTLN 583
Cdd:PLN00113 210 QMKSLKWIYLG------------YNNLSGEIPYEIGGLtslnhLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIP 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 584 GSEFYyLSELKYLDFSNNRIDLLYSTAFKELKLLEVLDLSYNKHY-FLAEGVThvlnfmkNLTYLKKLMMNENEISTSIS 662
Cdd:PLN00113 278 PSIFS-LQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKIPVALT-------SLPRLQVLQLWSNKFSGEIP 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 663 TGMESQS-LQVLEFKGNRL-----DVLWMDGNARYLSFFKN------------LTSLEKLDISFNSLSFLPPGVFEAMPP 724
Cdd:PLN00113 350 KNLGKHNnLTVLDLSTNNLtgeipEGLCSSGNLFKLILFSNslegeipkslgaCRSLRRVRLQDNSFSGELPSEFTKLPL 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 725 eLRILNLTSNKLKSFSWGKLQLLEKLITLDLS-NNLLLTVPRelSNCSSTIQELILRNNRIQRLTRHFLRGAFNLKYLDL 803
Cdd:PLN00113 430 -VYFLDISNNNLQGRINSRKWDMPSLQMLSLArNKFFGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKL 506
|
....*
gi 926488448 804 SSNKI 808
Cdd:PLN00113 507 SENKL 511
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
544-808 |
3.44e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 47.35 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 544 GETLDLSRNNIFFISPSDFQDLGfLRCLNLSGNAISQTlnGSEFYYLSELKYLDFS-NNRIDLLYST-----AFKELKLL 617
Cdd:cd00116 7 GELLKTERATELLPKLLCLQVLR-LEGNTLGEEAAKAL--ASALRPQPSLKELCLSlNETGRIPRGLqsllqGLTKGCGL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 618 EVLDLSYNkhYFLAEGVTHVLNFMKNLTyLKKLMMNENEISTSI------STGMESQSLQVLEFKGNRLDVlwmDGNARY 691
Cdd:cd00116 84 QELDLSDN--ALGPDGCGVLESLLRSSS-LQELKLNNNGLGDRGlrllakGLKDLPPALEKLVLGRNRLEG---ASCEAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 692 LSFFKNLTSLEKLDISFNSLsfLPPGV---FEAMP--PELRILNLTSNKLK----SFSWGKLQLLEKLITLDLSNNLLlt 762
Cdd:cd00116 158 AKALRANRDLKELNLANNGI--GDAGIralAEGLKanCNLEVLDLNNNGLTdegaSALAETLASLKSLEVLNLGDNNL-- 233
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 926488448 763 vprelsncsstiqelilRNNRIQRLTRHFLRGAFNLKYLDLSSNKI 808
Cdd:cd00116 234 -----------------TDAGAAALASALLSPNISLLTLSLSCNDI 262
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
537-659 |
4.02e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.93 E-value: 4.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 537 NEDCLKYGETLDLSRNNIFFISpsDFQDLGFLRCLNLSgnaiSQTL-NGSEF-------YYLSE-LKYLDFSNNRIDLLy 607
Cdd:cd21340 63 NLENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIE----NQRLpPGEKLtfdprslAALSNsLRVLNISGNNIDSL- 135
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 926488448 608 sTAFKELKLLEVLDLSYNKHyflaEGVTHVLNFMKNLTYLKKLMMNENEIST 659
Cdd:cd21340 136 -EPLAPLRNLEQLDASNNQI----SDLEELLDLLSSWPSLRELDLTGNPVCK 182
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
641-834 |
8.38e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.16 E-value: 8.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 641 MKNLTYLKklmMNENEIsTSISTGMESQSLQVLEFKGNRLDVlwMDGnaryLSFFKNLTSL-------EKLDiSFNSLsf 713
Cdd:cd21340 1 LKRITHLY---LNDKNI-TKIDNLSLCKNLKVLYLYDNKITK--IEN----LEFLTNLTHLylqnnqiEKIE-NLENL-- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 714 lppgvfeampPELRILNLTSNKLKSFSwGkLQLLEKLITLDLSNNLL-----LTV-PRELSNCSSTIQELILRNNRIQRL 787
Cdd:cd21340 68 ----------VNLKKLYLGGNRISVVE-G-LENLTNLEELHIENQRLppgekLTFdPRSLAALSNSLRVLNISGNNIDSL 135
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 926488448 788 TrhFLRGAFNLKYLDLSSNKIQIIKKSSFPENVINNLKMLLLHGNPF 834
Cdd:cd21340 136 E--PLAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
724-808 |
9.77e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 9.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 724 PELRILNLTSNKLKSFSWGKLQLLEKLITLDLSNNLLLTV-PRELSNCSStiqelilrnnriqrltrhflrgafnLKYLD 802
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPS-------------------------LRYLD 55
|
....*.
gi 926488448 803 LSSNKI 808
Cdd:pfam13855 56 LSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
297-370 |
1.61e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.59 E-value: 1.61e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 926488448 297 NLEILDLSGNcprcynapypctpcpkGTIEIHPKAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQN 370
Cdd:pfam13855 2 NLRSLDLSNN----------------RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
329-494 |
1.88e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.04 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 329 PKAFQSLKQLKILRLHSNSLQRILSSWFENTR---NLKELDLSQNFLAKEIGD--AQFLK-LIPSLVELDLSFNfqlQMY 402
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRllAKGLKdLPPALEKLVLGRN---RLE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 403 SPSL-NLSKTFSSLVNLEILRLR---------------GYVFKELKQENLDP--------------LLHLRNLTVLDLGT 452
Cdd:cd00116 151 GASCeALAKALRANRDLKELNLAnngigdagiralaegLKANCNLEVLDLNNngltdegasalaetLASLKSLEVLNLGD 230
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 926488448 453 NFIKVADLKVFKK-----FPALKFIDLSVNKISPSSGESNCyRFCPN 494
Cdd:cd00116 231 NNLTDAGAAALASallspNISLLTLSLSCNDITDDGAKDLA-EVLAE 276
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
95-396 |
2.25e-04 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 44.92 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 95 TVDCSDRRLTEIPRGIP--TNATNLTLTINHIPHVyPTSFAHLENLMEIDFRCNcvpvrlgpkdhvctrtpQIEN--GSF 170
Cdd:COG4886 163 SLDLSNNQLTDLPEELGnlTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN-----------------QLTDlpEPL 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 171 AALARLRSLYLDANQLLEIPrglpttlrllsleansifsitraNLSELRNIEVLYLGQNcyyrnpcnvsfEIEE-TAFLD 249
Cdd:COG4886 225 ANLTNLETLDLSNNQLTDLP-----------------------ELGNLTNLEELDLSNN-----------QLTDlPPLAN 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 250 LKNLTILSLKSNNLTyippnlSSTLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCPRCYNAPYPCTPCPKGTIEIHP 329
Cdd:COG4886 271 LTNLKTLDLSNNQLT------DLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSL 344
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 926488448 330 KAFQSLKQLKILRLHSNSLQRILSSWFENTRNLKELDLSQNFLAKEIGDAQFLKLIPSLVELDLSFN 396
Cdd:COG4886 345 SLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAV 411
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
653-835 |
4.74e-04 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 43.77 E-value: 4.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 653 NENEISTSISTGMESQSLQVLEFKGNRLDVLWMDGNARYLSFFKNLTSLEKLDISFNSLSFLPPGVFEAMPPELRILNLT 732
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 733 SNKLKSFSWGKLQLLEKLITLDLSNNllltvpRELSNCSStIQELILRNNRIQRLTrHFLRGAFNLKYLDLSSNKIqiik 812
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTN-LESLDLSGNQLTDLP-EELANLTNLKELDLSNNQL---- 148
|
170 180
....*....|....*....|....*
gi 926488448 813 kSSFPENVIN--NLKMLLLHGNPFK 835
Cdd:COG4886 149 -TDLPEPLGNltNLKSLDLSNNQLT 172
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
832-878 |
6.90e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 38.57 E-value: 6.90e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 926488448 832 NPFKCNCDAVWFVWWINQTQVTipLLATDVTCAGPGAHKGKSVVFLD 878
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHL--QDPVDLRCASPSSLRGPLLELLH 45
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
272-348 |
7.12e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 38.66 E-value: 7.12e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 926488448 272 STLKELYIYNNMIQVIQEHDLIALHNLEILDLSGNCPRCynapypctpcpkgtieIHPKAFQSLKQLKILRLHSNSL 348
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT----------------LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
272-396 |
1.38e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.96 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 272 STLKELYIYNNMIQV--IQE--HDLIALHNLEILDLSGNCPRCYNAPYPCtpcpkgtieihpKAFQSLKQLKILRLHSNS 347
Cdd:cd00116 165 RDLKELNLANNGIGDagIRAlaEGLKANCNLEVLDLNNNGLTDEGASALA------------ETLASLKSLEVLNLGDNN 232
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 348 L-----QRILSSWFENTRNLKELDLSQNflakEIGD------AQFLKLIPSLVELDLSFN 396
Cdd:cd00116 233 LtdagaAALASALLSPNISLLTLSLSCN----DITDdgakdlAEVLAEKESLLELDLRGN 288
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
195-263 |
2.72e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.12 E-value: 2.72e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 926488448 195 TTLRLLSLEANSIFSITRANLSELRNIEVLYLGQNCyyrnpCNVsfeIEETAFLDLKNLTILSLKSNNL 263
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL-----LTT---LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
591-834 |
4.09e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 41.37 E-value: 4.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 591 SELKYLDFSNNRIDLLYSTAFKELKLLEVLDLSYNKhyfLAEGVTHvlNFMKNLTYLKKLMMNENEISTSISTGMESqSL 670
Cdd:PLN00113 69 SRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQ---LSGPIPD--DIFTTSSSLRYLNLSNNNFTGSIPRGSIP-NL 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 671 QVLEFKGN--------------RLDVLWMDGNA---RYLSFFKNLTSLEKLDISFNSLSFLPPGVFEAMpPELRILNLTS 733
Cdd:PLN00113 143 ETLDLSNNmlsgeipndigsfsSLKVLDLGGNVlvgKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQM-KSLKWIYLGY 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 734 NKLKSFSWGKLQLLEKLITLDLS-NNLLLTVPRELSNCSStIQELILRNNRIQRLTRHFLRGAFNLKYLDLSSNKIQiik 812
Cdd:PLN00113 222 NNLSGEIPYEIGGLTSLNHLDLVyNNLTGPIPSSLGNLKN-LQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLS--- 297
|
250 260
....*....|....*....|....
gi 926488448 813 kSSFPENVIN--NLKMLLLHGNPF 834
Cdd:PLN00113 298 -GEIPELVIQlqNLEILHLFSNNF 320
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
95-116 |
5.89e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 5.89e-03
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
545-680 |
6.98e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.03 E-value: 6.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 926488448 545 ETLDLSRNNIFFIS----PSDFQDLGFLRCLNLSGNAIS----QTLnGSEFYYLSELKYLDFSNNRI----DLLYSTAFK 612
Cdd:cd00116 140 EKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGdagiRAL-AEGLKANCNLEVLDLNNNGLtdegASALAETLA 218
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 926488448 613 ELKLLEVLDLSYNKhyFLAEGVTHVLNFMKNL-TYLKKLMMNENEI----STSISTGM-ESQSLQVLEFKGNRL 680
Cdd:cd00116 219 SLKSLEVLNLGDNN--LTDAGAAALASALLSPnISLLTLSLSCNDItddgAKDLAEVLaEKESLLELDLRGNKF 290
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
698-720 |
8.47e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.47e-03
|
| LRR_TYP |
smart00369 |
Leucine-rich repeats, typical (most populated) subfamily; |
698-720 |
8.47e-03 |
|
Leucine-rich repeats, typical (most populated) subfamily;
Pssm-ID: 197687 [Multi-domain] Cd Length: 24 Bit Score: 34.63 E-value: 8.47e-03
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
360-425 |
8.77e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.58 E-value: 8.77e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 926488448 360 RNLKELDLSQNFLaKEIGDAQFLKLiPSLVELDLSFNfQLQMYSPslnlsKTFSSLVNLEILRLRG 425
Cdd:pfam13855 1 PNLRSLDLSNNRL-TSLDDGAFKGL-SNLKVLDLSNN-LLTTLSP-----GAFSGLPSLRYLDLSG 58
|
|
| |
