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Conserved domains on  [gi|950967711|ref|XP_014453962|]
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ataxin-2 isoform X8 [Alligator mississippiensis]

Protein Classification

PABP-interacting PAM2 motif-containing protein( domain architecture ID 10627809)

PABP-interacting PAM2 motif-containing protein similar to human polyadenylate-binding protein-interacting protein 2 (PAIP2) that acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 3-76 7.07e-22

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


:

Pssm-ID: 464173  Cd Length: 78  Bit Score: 90.30  E-value: 7.07e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711     3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHRKTAE--SSLGPKREDIVESILFKPSDFVMVQFK 76
Cdd:pfam14438    1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 144-205 5.38e-15

LsmAD domain; This domain is found associated with Lsm domain.


:

Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 70.29  E-value: 5.38e-15
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711   144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARATQLAEEIESSAQYKARLALENDDRT------EEEK 205
Cdd:pfam06741    1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDVddsgldEEDK 65
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 657-1039 6.72e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 6.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  657 RSFAQPKPSTTPTSP-------RPQAQPSPSM----VGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVN 725
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPavtsrarRPDAPPQSARprapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  726 QAKTYRAGKVPNMPQQRQDQHhQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVI 805
Cdd:PHA03247 2646 VPPPERPRDDPAPGRVSRPRR-ARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  806 QGNARMMAPPTHAQP-------GLVSSSATQYGAHEQTHAMYACPKIPYSKETGPsfyfAISTGSLAQQYAHPNATLHPH 878
Cdd:PHA03247 2725 PAAARQASPALPAAPappavpaGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP----PRRLTRPAVASLSESRESLPS 2800

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  879 PSHPQPSATP-TGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAP----------TPPAMTPGSNTQ 947
Cdd:PHA03247 2801 PWDPADPPAAvLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrrppsRSPAAKPAAPAR 2880

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  948 SPQNSFPtaqqtvftihpshvQPAYTNPPHMAHVPQAHVQSgmLPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVS 1027
Cdd:PHA03247 2881 PPVRRLA--------------RPAVSRSTESFALPPDQPER--PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         410
                  ....*....|..
gi 950967711 1028 TTTHFPYMTHPS 1039
Cdd:PHA03247 2945 PTTDPAGAGEPS 2956
PRK14954 super family cl33039
DNA polymerase III subunits gamma and tau; Provisional
 401-530 3.74e-04

DNA polymerase III subunits gamma and tau; Provisional


The actual alignment was detected with superfamily member PRK14954:

Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 44.55  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  401 GGPSGGTWSSVVSG---------VPRLSPKTHRPRSPRQSSGSTSAALSSPQAGTTPTESVAMPVPAASPTPASPASNRA 471
Cdd:PRK14954  374 VRNDGGVAPSPAGSpdvkkkapePDLPQPDRHPGPAKPEAPGARPAELPSPASAPTPEQQPPVARSAPLPPSPQASAPRN 453

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 950967711  472 VTPSSEAKDTRLQDQRQNTAAGNkentkPSETSPSFPKPENKGVSPvVSEHRKQIDDLK 530
Cdd:PRK14954  454 VASGKPGVDLGSWQGKFMNFTRN-----GSRKQPVQASSSDAAQTG-VFEGVAELEKLR 506
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
 643-658 3.78e-03

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


:

Pssm-ID: 429316  Cd Length: 17  Bit Score: 35.67  E-value: 3.78e-03
                           10
                   ....*....|....*.
gi 950967711   643 RKSTLNPNAKEFNPRS 658
Cdd:pfam07145    1 SKSKLNPNAKEFVPSF 16
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 3-76 7.07e-22

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 90.30  E-value: 7.07e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711     3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHRKTAE--SSLGPKREDIVESILFKPSDFVMVQFK 76
Cdd:pfam14438    1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 144-205 5.38e-15

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 70.29  E-value: 5.38e-15
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711   144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARATQLAEEIESSAQYKARLALENDDRT------EEEK 205
Cdd:pfam06741    1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDVddsgldEEDK 65
PHA03247 PHA03247
large tegument protein UL36; Provisional
 657-1039 6.72e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 6.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  657 RSFAQPKPSTTPTSP-------RPQAQPSPSM----VGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVN 725
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPavtsrarRPDAPPQSARprapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  726 QAKTYRAGKVPNMPQQRQDQHhQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVI 805
Cdd:PHA03247 2646 VPPPERPRDDPAPGRVSRPRR-ARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  806 QGNARMMAPPTHAQP-------GLVSSSATQYGAHEQTHAMYACPKIPYSKETGPsfyfAISTGSLAQQYAHPNATLHPH 878
Cdd:PHA03247 2725 PAAARQASPALPAAPappavpaGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP----PRRLTRPAVASLSESRESLPS 2800

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  879 PSHPQPSATP-TGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAP----------TPPAMTPGSNTQ 947
Cdd:PHA03247 2801 PWDPADPPAAvLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrrppsRSPAAKPAAPAR 2880

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  948 SPQNSFPtaqqtvftihpshvQPAYTNPPHMAHVPQAHVQSgmLPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVS 1027
Cdd:PHA03247 2881 PPVRRLA--------------RPAVSRSTESFALPPDQPER--PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         410
                  ....*....|..
gi 950967711 1028 TTTHFPYMTHPS 1039
Cdd:PHA03247 2945 PTTDPAGAGEPS 2956
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 643-801 8.83e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 46.34  E-value: 8.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   643 RKSTLNPNAKEFNPRSFAQPKPSttptsPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLypiPMTPM 722
Cdd:TIGR01628  367 RRAHLQDQFMQLQPRMRQLPMGS-----PMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLR---PNGLA 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   723 PVNQaktyrAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQ------ 796
Cdd:TIGR01628  439 PMNA-----VRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQVLASATPQMQKQvlgerl 513


                   ....*
gi 950967711   797 HPHVY 801
Cdd:TIGR01628  514 FPLVE 518
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 739-983 3.07e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.03  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   739 PQQRQDQHHQSTMMHPASAAGPPIVATPPAySTQYVAYS------------------PQQFPNQPLVQHVPHYQSQHPHV 800
Cdd:pfam09770  111 AAQSSAQPPASSLPQYQYASQQSQQPSKPV-RTGYEKYKepepipdlqvdaslwgvaPKKAAAPAPAPQPAAQPASLPAP 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   801 YSPV-----IQGNARMMAPPTHAQPGlvsSSATQYGAHEQTHAMYACPKIPYSKETGPSFYFAISTGSLAQQYAHPNATL 875
Cdd:pfam09770  190 SRKMmsleeVEAAMRAQAKKPAQQPA---PAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTIL 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   876 HPHPSHPQPSATPTGQQQSQHAGSHPAPSPVqhhqhqaAQALHLANPQQQSaiyhAGLAPTPPAMTPGSNTQSPQNSFPT 955
Cdd:pfam09770  267 QRPQSPQPDPAQPSIQPQAQQFHQQPPPVPV-------QPTQILQNPNRLS----AARVGYPQNPQPGVQPAPAHQAHRQ 335

                          250       260
                   ....*....|....*....|....*...
gi 950967711   956 AQqtvftiHPSHVQPAYTNPPHMAHVPQ 983
Cdd:pfam09770  336 QG------SFGRQAPIITHPQQLAQLSE 357
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 401-530 3.74e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 44.55  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  401 GGPSGGTWSSVVSG---------VPRLSPKTHRPRSPRQSSGSTSAALSSPQAGTTPTESVAMPVPAASPTPASPASNRA 471
Cdd:PRK14954  374 VRNDGGVAPSPAGSpdvkkkapePDLPQPDRHPGPAKPEAPGARPAELPSPASAPTPEQQPPVARSAPLPPSPQASAPRN 453

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 950967711  472 VTPSSEAKDTRLQDQRQNTAAGNkentkPSETSPSFPKPENKGVSPvVSEHRKQIDDLK 530
Cdd:PRK14954  454 VASGKPGVDLGSWQGKFMNFTRN-----GSRKQPVQASSSDAAQTG-VFEGVAELEKLR 506
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
 643-658 3.78e-03

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


Pssm-ID: 429316  Cd Length: 17  Bit Score: 35.67  E-value: 3.78e-03
                           10
                   ....*....|....*.
gi 950967711   643 RKSTLNPNAKEFNPRS 658
Cdd:pfam07145    1 SKSKLNPNAKEFVPSF 16
PHA03247 PHA03247
large tegument protein UL36; Provisional
 306-778 4.32e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  306 PNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPV-STMPK--RMSSEGPPRMSPKAQRHPRGHRVSTGRGTISSGL 382
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPqSARPRapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA 2635

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  383 EFVSHNAPGEASTATVARGGPSGGTWS-----SVVSGVPRLSPKTHRPRSP--RQSSGSTSAALSSPQAGTTPtESVAMP 455
Cdd:PHA03247 2636 NEPDPHPPPTVPPPERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRaaRPTVGSLTSLADPPPPPPTP-EPAPHA 2714

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  456 VPAASPTPASPASNRAVTPSSEAkDTRLQDQRQNTAAGNKENTKPSETSPSFPKPENKGVSPVVSEhrkqiddlkkfknd 535
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPA-APAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP-------------- 2779

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  536 frlQPSSTPDTVDQLLNKNRENEKSRDTMKEKTESTSKESVVETSSNANSNSGSSKPNSPSISPSISSSSEQkrgPEVTS 615
Cdd:PHA03247 2780 ---PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP---SLPLG 2853

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  616 QGVQTSGPGSKQEKEDKEEKKDTA-EQVRKSTLNPNAKEFNPRSFAQPkpsttPTSPRPQAQPSPsmvghqqPTPVYTQP 694
Cdd:PHA03247 2854 GSVAPGGDVRRRPPSRSPAAKPAApARPPVRRLARPAVSRSTESFALP-----PDQPERPPQPQA-------PPPPQPQP 2921

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  695 VCFAPNMMYPVPVSPgvqPLYPIPMTPMPVNQAKTYRAGKVPNmpqqrqdqhHQSTMMHPASAAGPPIVATPPAYSTQYV 774
Cdd:PHA03247 2922 QPPPPPQPQPPPPPP---PRPQPPLAPTTDPAGAGEPSGAVPQ---------PWLGALVPGRVAVPRFRVPQPAPSREAP 2989


                  ....
gi 950967711  775 AYSP 778
Cdd:PHA03247 2990 ASST 2993
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
 3-76 7.07e-22

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 90.30  E-value: 7.07e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711     3 MVHILTSVVGSKCEVQVKNGGIYEGVFKTYSP--KCDLVLDAAHRKTAE--SSLGPKREDIVESILFKPSDFVMVQFK 76
Cdd:pfam14438    1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASLekDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
 144-205 5.38e-15

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 70.29  E-value: 5.38e-15
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 950967711   144 YGVVSTYDSSLssYTVPLERdNSEEFLKREARATQLAEEIESSAQYKARLALENDDRT------EEEK 205
Cdd:pfam06741    1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERGLDVddsgldEEDK 65
PHA03247 PHA03247
large tegument protein UL36; Provisional
 657-1039 6.72e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 6.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  657 RSFAQPKPSTTPTSP-------RPQAQPSPSM----VGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVN 725
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPavtsrarRPDAPPQSARprapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  726 QAKTYRAGKVPNMPQQRQDQHhQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVI 805
Cdd:PHA03247 2646 VPPPERPRDDPAPGRVSRPRR-ARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  806 QGNARMMAPPTHAQP-------GLVSSSATQYGAHEQTHAMYACPKIPYSKETGPsfyfAISTGSLAQQYAHPNATLHPH 878
Cdd:PHA03247 2725 PAAARQASPALPAAPappavpaGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP----PRRLTRPAVASLSESRESLPS 2800

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  879 PSHPQPSATP-TGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAP----------TPPAMTPGSNTQ 947
Cdd:PHA03247 2801 PWDPADPPAAvLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrrppsRSPAAKPAAPAR 2880

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  948 SPQNSFPtaqqtvftihpshvQPAYTNPPHMAHVPQAHVQSgmLPSHPTAHAPMMLMTTQPPGGPQAAIAQSALQPIPVS 1027
Cdd:PHA03247 2881 PPVRRLA--------------RPAVSRSTESFALPPDQPER--PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         410
                  ....*....|..
gi 950967711 1028 TTTHFPYMTHPS 1039
Cdd:PHA03247 2945 PTTDPAGAGEPS 2956
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 643-801 8.83e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 46.34  E-value: 8.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   643 RKSTLNPNAKEFNPRSFAQPKPSttptsPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLypiPMTPM 722
Cdd:TIGR01628  367 RRAHLQDQFMQLQPRMRQLPMGS-----PMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLR---PNGLA 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   723 PVNQaktyrAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQ------ 796
Cdd:TIGR01628  439 PMNA-----VRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQVLASATPQMQKQvlgerl 513


                   ....*
gi 950967711   797 HPHVY 801
Cdd:TIGR01628  514 FPLVE 518
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 657-939 2.14e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.46  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  657 RSFAQPKPSTTPTSPRPQAQPSPS--------MVGHQQPTPVYT-QPVCFAPNMMYPVPVSPGVQPLypipmtPMPVNQA 727
Cdd:PRK10263  331 QSWAAPVEPVTQTPPVASVDVPPAqptvawqpVPGPQTGEPVIApAPEGYPQQSQYAQPAVQYNEPL------QQPVQPQ 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  728 KTYRAGKVPNMPQQRQDQHHQSTmmhPASAAGPPIVATPPAYSTQYVAYspqqfPNQPLVQHVPHYQSQHPHVySPVIQg 807
Cdd:PRK10263  405 QPYYAPAAEQPAQQPYYAPAPEQ---PAQQPYYAPAPEQPVAGNAWQAE-----EQQSTFAPQSTYQTEQTYQ-QPAAQ- 474

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  808 narmmaPPTHAQPGLVsssatqygahEQTHAMYACPKIPYSKETGPS-FYFAISTGSLAQQYAHPNATLHPhpsHPQPSA 886
Cdd:PRK10263  475 ------EPLYQQPQPV----------EQQPVVEPEPVVEETKPARPPlYYFEEVEEKRAREREQLAAWYQP---IPEPVK 535

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 950967711  887 TPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLanpqqQSAIYHAGLAPTPPA 939
Cdd:PRK10263  536 EPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGV-----KKATLATGAAATVAA 583
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 739-983 3.07e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.03  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   739 PQQRQDQHHQSTMMHPASAAGPPIVATPPAySTQYVAYS------------------PQQFPNQPLVQHVPHYQSQHPHV 800
Cdd:pfam09770  111 AAQSSAQPPASSLPQYQYASQQSQQPSKPV-RTGYEKYKepepipdlqvdaslwgvaPKKAAAPAPAPQPAAQPASLPAP 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   801 YSPV-----IQGNARMMAPPTHAQPGlvsSSATQYGAHEQTHAMYACPKIPYSKETGPSFYFAISTGSLAQQYAHPNATL 875
Cdd:pfam09770  190 SRKMmsleeVEAAMRAQAKKPAQQPA---PAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTIL 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   876 HPHPSHPQPSATPTGQQQSQHAGSHPAPSPVqhhqhqaAQALHLANPQQQSaiyhAGLAPTPPAMTPGSNTQSPQNSFPT 955
Cdd:pfam09770  267 QRPQSPQPDPAQPSIQPQAQQFHQQPPPVPV-------QPTQILQNPNRLS----AARVGYPQNPQPGVQPAPAHQAHRQ 335

                          250       260
                   ....*....|....*....|....*...
gi 950967711   956 AQqtvftiHPSHVQPAYTNPPHMAHVPQ 983
Cdd:pfam09770  336 QG------SFGRQAPIITHPQQLAQLSE 357
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 401-530 3.74e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 44.55  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  401 GGPSGGTWSSVVSG---------VPRLSPKTHRPRSPRQSSGSTSAALSSPQAGTTPTESVAMPVPAASPTPASPASNRA 471
Cdd:PRK14954  374 VRNDGGVAPSPAGSpdvkkkapePDLPQPDRHPGPAKPEAPGARPAELPSPASAPTPEQQPPVARSAPLPPSPQASAPRN 453

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 950967711  472 VTPSSEAKDTRLQDQRQNTAAGNkentkPSETSPSFPKPENKGVSPvVSEHRKQIDDLK 530
Cdd:PRK14954  454 VASGKPGVDLGSWQGKFMNFTRN-----GSRKQPVQASSSDAAQTG-VFEGVAELEKLR 506
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 640-906 1.47e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.72  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   640 EQVRKSTLNPNAKEFNP--RSFAQPKPSTTPTSPRPQAQPSPSMVG---HQQPTPVytqpvcfaPNM-----MYPVPVSP 709
Cdd:pfam09770   98 EQVRFNRQQPAARAAQSsaQPPASSLPQYQYASQQSQQPSKPVRTGyekYKEPEPI--------PDLqvdasLWGVAPKK 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   710 GVQPLYPIPMTPMPVNQAKTYRagKV--------------PNMPQQRQDQHHQstmmhpasaagppivatPPAYSTQYVA 775
Cdd:pfam09770  170 AAAPAPAPQPAAQPASLPAPSR--KMmsleeveaamraqaKKPAQQPAPAPAQ-----------------PPAAPPAQQA 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   776 YSPQQFPNQPLVQHVPHYQSQHPhvysPVIQGNARMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKIPysketGPSf 855
Cdd:pfam09770  231 QQQQQFPPQIQQQQQPQQQPQQP----QQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPV-----QPT- 300

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 950967711   856 yfaistgslaQQYAHPN---ATLHPHPSHPQPSATPT-GQQQSQHAGSHPAPSPV 906
Cdd:pfam09770  301 ----------QILQNPNrlsAARVGYPQNPQPGVQPApAHQAHRQQGSFGRQAPI 345
PHA03247 PHA03247
large tegument protein UL36; Provisional
 455-957 2.72e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  455 PVPAASPTPASPASNRAVTPSSEAKdtrlqdQRQNTAAGNKentkpsETSPSFPKPENKGVSPVvsehrkqiDDlkkfKN 534
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAP------RPSEPAVTSR------ARRPDAPPQSARPRAPV--------DD----RG 2606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  535 DFRLQPSSTPDTVDqllnknreneksrdtmkektestskesvvetSSNANSNSGSSKPNSPSISPSISSSSEQKRGPEVT 614
Cdd:PHA03247 2607 DPRGPAPPSPLPPD-------------------------------THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDD 2655

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  615 SQGVQTSGPGSKQEKEDKEEKKDTAEQVRKSTLNPNAKEFNprSFAQPKPSTTPTSPRPQAQPSPSmvghqqPTPVYTQP 694
Cdd:PHA03247 2656 PAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLT--SLADPPPPPPTPEPAPHALVSAT------PLPPGPAA 2727

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  695 VCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQqrqdqhhqstmmhpASAAGPPIVATPPAYSTQYV 774
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA--------------APAAGPPRRLTRPAVASLSE 2793

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  775 AYSPQQFPNQPLVQHVPhyqSQHPHVYSPVIQGNARMMAPPTHAQPglvSSSATQYGAHEQTHAM--YACPKIPYSKEtG 852
Cdd:PHA03247 2794 SRESLPSPWDPADPPAA---VLAPAAALPPAASPAGPLPPPTSAQP---TAPPPPPGPPPPSLPLggSVAPGGDVRRR-P 2866

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  853 PSfyfaistgslAQQYAHPNATLHPHPSH-PQPSATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHA 931
Cdd:PHA03247 2867 PS----------RSPAAKPAAPARPPVRRlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP 2936

                         490       500
                  ....*....|....*....|....*..
gi 950967711  932 GLAPTPPAMTPGSNTQS-PQNSFPTAQ 957
Cdd:PHA03247 2937 PRPQPPLAPTTDPAGAGePSGAVPQPW 2963
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 611-1033 3.10e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 41.68  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   611 PEVTSQGVQTSGPGSKQEKEDKEEKKDTAEQVRKSTLNPNAKEFNPRSFAQPKPSTTPTSPRPQAQPSPSMVGHQQPTPV 690
Cdd:pfam03154  134 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPA 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   691 YTQPvcfapnmmyPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQ-----QRQDQHHQSTMMHPASAAGPPIVAT 765
Cdd:pfam03154  214 TSQP---------PNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQppppsQVSPQPLPQPSLHGQMPPMPHSLQT 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   766 PPaystqyvAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAppthAQPGLVSSSATQYGAHEQthamyACPKI 845
Cdd:pfam03154  285 GP-------SHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI----HTPPSQSQLQSQQPPREQ-----PLPPA 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   846 PYS-KETGPSFYFAISTGSLAQQYAHPnatlhPHPSHPQPSATPTgqqqsqhagSHPAPSPVQHHQHQAAQALHLANPQQ 924
Cdd:pfam03154  349 PLSmPHIKPPPTTPIPQLPNPQSHKHP-----PHLSGPSPFQMNS---------NLPPPPALKPLSSLSTHHPPSAHPPP 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711   925 QSAIYHAGLAPTPPAMTPGSnTQSPQNSFPTAQQ-TVFTIHPSHVQPAYTNPPHMAHVPqahvQSGMLPSHPTAHAPMML 1003
Cdd:pfam03154  415 LQLMPQSQQLPPPPAQPPVL-TQSQSLPPPAASHpPTSGLHQVPSQSPFPQHPFVPGGP----PPITPPSGPPTSTSSAM 489

                          410       420       430
                   ....*....|....*....|....*....|
gi 950967711  1004 MTTQPPGGPQAAIAqsalQPIPVSTTTHFP 1033
Cdd:pfam03154  490 PGIQPPSSASVSSS----GPVPAAVSCPLP 515
PAM2 pfam07145
Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various ...
 643-658 3.78e-03

Ataxin-2 C-terminal region; The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for pfam00658. It has been found in a wide range of eukaryotic proteins. Strikingly, this motif appears to occur solely outside of globular domains.


Pssm-ID: 429316  Cd Length: 17  Bit Score: 35.67  E-value: 3.78e-03
                           10
                   ....*....|....*.
gi 950967711   643 RKSTLNPNAKEFNPRS 658
Cdd:pfam07145    1 SKSKLNPNAKEFVPSF 16
PHA03247 PHA03247
large tegument protein UL36; Provisional
 306-778 4.32e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 4.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  306 PNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPV-STMPK--RMSSEGPPRMSPKAQRHPRGHRVSTGRGTISSGL 382
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPqSARPRapVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA 2635

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  383 EFVSHNAPGEASTATVARGGPSGGTWS-----SVVSGVPRLSPKTHRPRSP--RQSSGSTSAALSSPQAGTTPtESVAMP 455
Cdd:PHA03247 2636 NEPDPHPPPTVPPPERPRDDPAPGRVSrprraRRLGRAAQASSPPQRPRRRaaRPTVGSLTSLADPPPPPPTP-EPAPHA 2714

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  456 VPAASPTPASPASNRAVTPSSEAkDTRLQDQRQNTAAGNKENTKPSETSPSFPKPENKGVSPVVSEhrkqiddlkkfknd 535
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPA-APAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP-------------- 2779

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  536 frlQPSSTPDTVDQLLNKNRENEKSRDTMKEKTESTSKESVVETSSNANSNSGSSKPNSPSISPSISSSSEQkrgPEVTS 615
Cdd:PHA03247 2780 ---PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP---SLPLG 2853

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  616 QGVQTSGPGSKQEKEDKEEKKDTA-EQVRKSTLNPNAKEFNPRSFAQPkpsttPTSPRPQAQPSPsmvghqqPTPVYTQP 694
Cdd:PHA03247 2854 GSVAPGGDVRRRPPSRSPAAKPAApARPPVRRLARPAVSRSTESFALP-----PDQPERPPQPQA-------PPPPQPQP 2921

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  695 VCFAPNMMYPVPVSPgvqPLYPIPMTPMPVNQAKTYRAGKVPNmpqqrqdqhHQSTMMHPASAAGPPIVATPPAYSTQYV 774
Cdd:PHA03247 2922 QPPPPPQPQPPPPPP---PRPQPPLAPTTDPAGAGEPSGAVPQ---------PWLGALVPGRVAVPRFRVPQPAPSREAP 2989


                  ....
gi 950967711  775 AYSP 778
Cdd:PHA03247 2990 ASST 2993
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
405-513 4.85e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 40.91  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  405 GGTWSSVVSGVPRLSPKTHRPRSPRQSSGSTSAALSSPQAGTTPTESVAMPVPAASPTPasPASNRAVTPSSEAkdtrlq 484
Cdd:PRK14971  366 GDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTP--PTVSVDPPAAVPV------ 437

                          90       100
                  ....*....|....*....|....*....
gi 950967711  485 dqrqntaagNKENTKPSETSPSFPKPENK 513
Cdd:PRK14971  438 ---------NPPSTAPQAVRPAQFKEEKK 457
PHA03247 PHA03247
large tegument protein UL36; Provisional
 648-1006 7.11e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 7.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  648 NPNAKEFNPRSFAQPKPSTTPTSPRPQA--QPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVN 725
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAarQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  726 QAKTYRAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHvySPVI 805
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG--GSVA 2857

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  806 QGNARMMAPPTHAQPGLVSSSatqygaheqthamyacPKIPYSKETGPSfyFAISTGSLAQQyahPNATLHPHPSHPQPS 885
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAP----------------ARPPVRRLARPA--VSRSTESFALP---PDQPERPPQPQAPPP 2916

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 950967711  886 ATPTGQQQSQHAGSHPAPSPVQHHQHQAAQALHLANPQQQSAIYHAGLAPTPPAMTPGSNTQSPQNSfptaqqtvftihP 965
Cdd:PHA03247 2917 PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA------------P 2984

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 950967711  966 SHVQPA-YTNPPHMAHVPQAHVQSGMLPSH-PTAHAPMMLMTT 1006
Cdd:PHA03247 2985 SREAPAsSTPPLTGHSLSRVSSWASSLALHeETDPPPVSLKQT 3027
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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