|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
29-445 |
0e+00 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 775.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 29 GNGNADGKPKARRREADPAAALAAARHEFGEHGGVNMSIEASATFTVMEPDTMRRLFSGELGPERgDLYIYSRHFNPTVL 108
Cdd:PLN02242 1 GMSEKEKKSPAESKEEDPAAALASARHEFGEHGGVNMSIEASATFTVMEPDTMRRMFSGELGPDR-DFYIYSRHFNPTVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 109 ALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRASGVRATFVDADDEAAVRAAV 188
Cdd:PLN02242 80 NLGRQMAALEGTEAAYCTASGMSAISSVLLQLCSSGGHVVASNTLYGGTHALLAHFLPRKCNITTTFVDITDLEAVKKAV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 189 RPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTFTPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGP 268
Cdd:PLN02242 160 VPGKTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTFAPMVLSPARLGADVVVHSISKFISGGADIIAGAVCGP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 269 ASLVNAMMDLQEGALMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLGLRVAYPGLPDHPHHARLLAIA 348
Cdd:PLN02242 240 AELVNSMMDLHHGALMLLGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELGLKVIYPGLEDHPQHALLKSMA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 349 NPGYGAGGMLCVDMGTEDRANRLMHHLQNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYN 428
Cdd:PLN02242 320 NKGYGFGGLLCLDMDTEERANRLMRYLQNSTQFGFMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGYT 399
|
410
....*....|....*..
gi 1002302115 429 GTLEQRWAQFERALSLM 445
Cdd:PLN02242 400 GTLEQRWSQFEKALSAM 416
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
61-443 |
8.67e-147 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 423.54 E-value: 8.67e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 61 GGVNMSIEASATFTVMEPDTMRRLFSGelgpeRGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQL 140
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADLFAL-----REGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLAL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 141 VGAGGHVVASRCLYGGTHALLSRFLPRaSGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHD 220
Cdd:cd00614 76 LKAGDHVVASDDLYGGTYRLFERLLPK-LGIEVTFVDPDDPEALEAAIKP-ETKLVYVESPTNPTLKVVDIEAIAELAHE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 221 AGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDLQEGAlmlLGPTMNAKVAFELS 299
Cdd:cd00614 154 HGALLVVDNTFaTPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLA---LGTILSPFDAWLLL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 300 ERLPHLPLRMQEHSRRAAEYASRMRRLG--LRVAYPGLPDHPHHArLLAIANPGYgaGGMLCVDMGTEDRAnrlMHHLQN 377
Cdd:cd00614 231 RGLKTLPLRMERHSENALKVAEFLEKHPkvERVYYPGLPSHPQHE-LAKKQMSGY--GGVFSFELKGGLEA---AKKFLN 304
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002302115 378 TTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNgTLEQRWAQFERALS 443
Cdd:cd00614 305 ALKLFSLAVSLGGVESLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIE-DVEDLIADLEQALK 369
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
54-443 |
2.37e-120 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 356.67 E-value: 2.37e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 54 RHEFGEHGGVNMSIEASATFTVMEPDTMRRLFSGELGPergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAI 133
Cdd:COG0626 12 RDPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGG-----YIYSRYGNPTRRALEEALAALEGGEAALAFASGMAAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 134 SSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPM 213
Cdd:COG0626 87 SAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARF-GIEVTFVDPTDLAAVEAAIRP-NTKLVFLETPSNPTLEVVDIAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 214 LARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMdlqEGALMLLGPTMNA 292
Cdd:COG0626 165 IAAIAHAAGALLVVDNTFaTPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERL---RFLQNALGAVLSP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 293 KVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDM-GTEDRAN 369
Cdd:COG0626 242 FDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAvaRVYYPGLPSHPGHELAKRQMS---GFGGMLSFELkGGREAAR 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1002302115 370 RLMHHLqnttRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGyngtLEQR---WAQFERALS 443
Cdd:COG0626 319 RFLDAL----KLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVG----LEDVddlIADLEQALA 387
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
60-426 |
4.45e-95 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 291.83 E-value: 4.45e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 60 HGGVNMSIEASATFTvmepdtmrrlFSGElGPERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQ 139
Cdd:pfam01053 15 TGAVSVPIYLTSTYV----------FDFA-GEEGG--YDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITAAILA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 140 LVGAGGHVVASRCLYGGTHALLSRFLPRaSGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAH 219
Cdd:pfam01053 82 LLKAGDHIVATDDLYGGTYRLFNKVLPR-FGIEVTFVDTSDPEDLEAAIKP-NTKAVYLETPTNPLLKVVDIEAIAKLAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 220 DAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPA-SLVNAMMDLQEGalmlLGPTMNAKVAFE 297
Cdd:pfam01053 160 KHGILVVVDNTFaSPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGeELGKELYFLQNA----TGAVLSPFDAWL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 298 LSERLPHLPLRMQEHSRRA---AEYASRMRRLGlRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDM-GTEDRANRLMH 373
Cdd:pfam01053 236 LLRGLKTLGLRMEQHQENAqkvAEFLESHPKVE-KVYYPGLPSHPGHELAKRQMK---GFGGMLSFELkGGLEAAKKFLD 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1002302115 374 HLQNTTrfglMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:pfam01053 312 NLKLFS----LAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVG 360
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
54-426 |
5.98e-82 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 258.39 E-value: 5.98e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 54 RHEFGEHGGVnMSIEASATFTVMEPDTMRrlFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAI 133
Cdd:PRK08133 18 RSPFGEHSEA-LFLTSSFVFESAAEAAAR--FAGE---EPG--NIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 134 SSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPM 213
Cdd:PRK08133 90 LAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARF-GIETTFVDLTDLDAWRAAVRP-NTKLFFLETPSNPLTELADIAA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 214 LARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMdlqeGALMLLGPTMNA 292
Cdd:PRK08133 168 LAEIAHAAGALLVVDNCFcTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVF----GFLRTAGPTLSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 293 KVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLG--LRVAYPGLPDHPHHArlLAiANPGYGAGGMLCVDM-GTEDRAN 369
Cdd:PRK08133 244 FNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPgvERVFYPGLPSHPQHE--LA-KRQQKGGGAIVSFEVkGGREAAW 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1002302115 370 RLMhhlqNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08133 321 RVI----DATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVG 373
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
79-426 |
2.08e-81 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 258.04 E-value: 2.08e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 79 DTMRRLFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTH 158
Cdd:COG2873 42 EHAADLFALK---EPG--NIYTRIMNPTTDVLEKRIAALEGGVAALATASGQAAITLAILNLAEAGDHIVASSSLYGGTY 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 159 ALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVS 237
Cdd:COG2873 117 NLFAHTLPRL-GIEVRFVDPDDPEAFEAAIDP-NTKAIFGETIGNPALDVLDIEAIAEIAHEHGVPLIVDNTFaTPYLCR 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 238 PARLGADVVVHSVSKFISGGADIIAGAI--------------------------------CGPASL-----VNAMMDlqe 280
Cdd:COG2873 195 PIEHGADIVVHSATKYIGGHGTSIGGVIvdggnfdwaangkfpeltepdpsyhglvyteaFGNAAFitkarVQLLRD--- 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 281 galmlLGPTMNAKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLgLRVAYPGLPDHPHHA---RLLaianPGyGA 354
Cdd:COG2873 272 -----LGAALSPFNAFLLLQGLETLSLRMERHVENAlkvAEFLEAHPKV-AWVNYPGLPSHPYHElaqKYL----PK-GA 340
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002302115 355 GGMLCVDM-GTEDRANRLMHHLQnttRFGLMAvSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:COG2873 341 GGVLTFGLkGGREAGKKFIDSLK---LFSHLA-NIGDAKSLVIHPASTTHSQLSEEEQAAAGVTPDLIRLSVG 409
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
56-442 |
2.14e-77 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 246.96 E-value: 2.14e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 56 EFGEHGGVNMSIEASATFTVmepDTMRRLFSGELGPERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISS 135
Cdd:PRK08249 20 EYLPYGATQVPVVLSVAYGY---DDIDEWYDVALGKKPG--HIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 136 VLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPGETrVVYVETMSNPTLAVADIPMLA 215
Cdd:PRK08249 95 TLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRM-GVDVTLCETGDHEQIEAEIAKGCD-LLYLETPTNPTLKIVDIERLA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 216 RVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDLQEgalmLLGPTMNAKV 294
Cdd:PRK08249 173 AAAKKVGALVVVDNTFaTPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVYHYRE----INGATMDPMS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 295 AFELSERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHarllAIANPGY-GAGGMLC-VDMGTEDRANR 370
Cdd:PRK08249 249 AYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKveAVYYPGLETHPNH----EIAKAQMrGFGGILSfVLKGGMDTVKR 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002302115 371 LMHHLqnttRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNGTlEQRWAQFERAL 442
Cdd:PRK08249 325 LLPKL----RYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDT-EDLIADLEQAF 391
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
54-426 |
1.02e-76 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 244.76 E-value: 1.02e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 54 RHEFGEHggvNMSIEASATFTVMEPDTMRRLFSGELgpergDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAI 133
Cdd:TIGR01325 11 RSGFEET---AEALYLTSGYVYDSAAVAAKRFAGEL-----PGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMAAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 134 SSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPM 213
Cdd:TIGR01325 83 FAALMALLGAGDHVVASRSLFGSCFVVCSEILPRF-GVQTVFVDGTDLSAWEAALKP-NTKAVFVETPSNPLQELVDIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 214 LARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLvnaMMDLQEGALMLLGPTMNA 292
Cdd:TIGR01325 161 VAELAHAAGAKVVVDNVFaTPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEY---MDEPVQKLLRHTGPAMSP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 293 KVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLGlRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDRAN 369
Cdd:TIGR01325 238 FNAWVLLKGLETLAIRVQHQNASAlaiAEWLNGHPSVQ-WVYYPGLPSHPQHELAKRQMS---GGGTVVTFDLDCRQAAF 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1002302115 370 RLMhhlqNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:TIGR01325 314 KVL----DAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVG 366
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
59-442 |
1.30e-74 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 239.40 E-value: 1.30e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 59 EHGGVNMSIEASATFTVMEPDTMRRLFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLM 138
Cdd:TIGR01328 18 QFGALTPPIYQTSTFVFDSCEQGGNRFAGQ---ESG--YIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMGAIAATLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 139 QLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVA 218
Cdd:TIGR01328 93 TILKAGDHLISDECLYGCTFALLEHALTKF-GIQVDFINMAIPEEVKAHIKD-NTKIVYFETPANPTMKLIDMERVCRDA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 219 HDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMdlQEGALMLLGPTMNAKVAFE 297
Cdd:TIGR01328 171 HSQGVKVIVDNTFaTPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIR--MVGIKDMTGSVISPFDAWL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 298 LSERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHArllAIANPGYGAGGMLCVDM-GTEDRANRLMHH 374
Cdd:TIGR01328 249 ILRGLKTLNIRMKRHSENAMKVAEYLKSHPAveKVYYPGFEDHPGHD---IAAKQMRMGGGMITFELkGGFAGAKKLLNN 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002302115 375 LQNTTRfglmAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNgTLEQRWAQFERAL 442
Cdd:TIGR01328 326 LKLIRL----AVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLE-DADDLIADLKQAL 388
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
59-445 |
5.32e-74 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 238.19 E-value: 5.32e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 59 EHGGVNMSIEASATFTVMEPDTMRRLFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLM 138
Cdd:PRK06234 23 QFGSLATPIYQTSTFIFDSAEQGGRRFAGE---ESG--YIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMGAISSSLW 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 139 QLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVA 218
Cdd:PRK06234 98 SALKAGDHVVASDTLYGCTFALLNHGLTRY-GVEVTFVDTSNLEEVRNALKA-NTKVVYLETPANPTLKVTDIKAISNIA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 219 HDA--GAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDLqeGALMLLGPTMNAKVA 295
Cdd:PRK06234 176 HENnkECLVFVDNTFcTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVKLF--GIKDMTGSVIGPFEA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 296 FELSERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHArlLA---IANPgygaGGMLCVDM-GTEDRAN 369
Cdd:PRK06234 254 FLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAveKVYYPGLESFEYYE--LAkkqMSLP----GAMISFELkGGVEEGK 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002302115 370 RLMhhlqNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNgTLEQRWAQFERALSLM 445
Cdd:PRK06234 328 VVM----NNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLE-DVDDIIADLKQALDLI 398
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
60-442 |
6.31e-72 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 233.40 E-value: 6.31e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 60 HGGVNMSIEASATFTVMEPDTMRRLFS-GELGpergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLM 138
Cdd:TIGR01326 17 TGSRAVPIYQTTSYVFDSTEHAAALFGlQEPG------NIYSRLMNPTTDVLEQRIAALEGGVAALAVASGQAAITYAIL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 139 QLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVA 218
Cdd:TIGR01326 91 NLAGAGDNIVSSSYLYGGTYNLFSHTLKRL-GIEVRFVDPDDPESLEKAIDE-NTKAVFAETIGNPQINVLDIEAIAEVA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 219 HDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAI----------------CGPA----------SL 271
Cdd:TIGR01326 169 HRHGIPLIVDNTFaTPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIvdggkfdwnngrfplfTTPDpsyhglvfteTL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 272 VNAMMDLQEGALML--LGPTMNAKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLgLRVAYPGLPDHPHHArlLA 346
Cdd:TIGR01326 249 GNPAFILKARVQLLrdLGAALSPFNAFLLLQGLETLSLRMERHVENAlkvAEFLESHPDV-AWVNYPGLASHPHHA--LA 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 347 IANPGYGAGGMLCVDM-GTEDRANRLMHHLQNTTRfglmAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSV 425
Cdd:TIGR01326 326 KKYLPKGFGAVLSFEIkGGREAGKKFIDALKLASH----LANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRLSV 401
|
410
....*....|....*..
gi 1002302115 426 GYNGtLEQRWAQFERAL 442
Cdd:TIGR01326 402 GIEN-IDDIIADLEQAL 417
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
87-426 |
4.25e-67 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 219.55 E-value: 4.25e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 87 GELGP-ERGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFl 165
Cdd:PRK08574 34 GEAYPsDRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAISTLFFSLLKAGDRVVLPMEAYGTTLRLLKSL- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 166 pRASGVRATFVDADDEAAVRAaVRPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGAD 244
Cdd:PRK08574 113 -EKFGVKVVLAYPSTEDIIEA-IKEGRTKLVFIETMTNPTLKVIDVPEVAKAAKELGAILVVDNTFaTPLLYRPLRHGAD 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 245 VVVHSVSKFISGGADIIAGAICGPASLVnaMMDLQEGALMlLGPTMNAKVAFeLSER-LPHLPLRMQEHSRRA---AEYA 320
Cdd:PRK08574 191 FVVHSLTKYIAGHNDVVGGVAVAWSGEF--LEELWEWRRR-LGTIMQPFEAY-LVLRgLKTLEVRFERQCRNAmaiAEFL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 321 SRMRRLGlRVAYPGLPDHPHH--ARLLaIANPGYgaGGMLCVDM-GTEDRANRLMHHLQNTTRfglmAVSLGYYETLMSC 397
Cdd:PRK08574 267 SEHPKVA-EVYYPGLPSDPYHgvAKRL-FGKDLY--GGVVSFRVkGGRDAVLKFLRSLKLIKP----SPSLGGVESLATY 338
|
330 340
....*....|....*....|....*....
gi 1002302115 398 SGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08574 339 PVKSAASPIPEEDRKALGITEDLVRLSVG 367
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
97-426 |
1.17e-66 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 218.44 E-value: 1.17e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMqLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFV 176
Cdd:PRK07671 42 YEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM-LFSSGDHVILTDDVYGGTYRVMTKVLNRF-GIEHTFV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK07671 120 DTSNLEEVEEAIRP-NTKAIYVETPTNPLLKITDIKKISTIAKEKGLLTIVDNTFmTPYWQSPISLGADIVLHSATKYLG 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAG-AICGPASLVNAMMDLQEGALMLLGPtmnaKVAFELSERLPHLPLRMQEH---SRRAAEYASRMRRLGlRVA 331
Cdd:PRK07671 199 GHSDVVAGlVVVNSPELAEDLHFVQNSTGGILGP----QDSWLLLRGLKTLGIRMEEHetnSRAIAEFLNNHPAVN-KVY 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 332 YPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDRANRLMHHLQNTTrfglMAVSLGYYETLMSCSGSSTSSEMPPEDR 411
Cdd:PRK07671 274 YPGLPSHPNHELAKEQAN---GFGGMISFDVGSEETANKVLERLQYFT----LAESLGAVESLISIPSQMTHASIPADRR 346
|
330
....*....|....*
gi 1002302115 412 ARAGISPGLVRMSVG 426
Cdd:PRK07671 347 KELGITDGLIRISVG 361
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
61-426 |
4.50e-66 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 217.21 E-value: 4.50e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 61 GGVNMSIEASATFTVMEPDTMRrlfSGelgpergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQL 140
Cdd:PRK07811 29 GAVNPPIYASSTFAQDGVGGLR---GG---------YEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAATDCLLRAV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 141 VGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHD 220
Cdd:PRK07811 97 LRPGDHIVIPNDAYGGTFRLIDKVFTRW-GVEYTPVDLSDLDAVRAAITP-RTKLIWVETPTNPLLSITDIAALAELAHD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 221 AGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGA-ICGPASLVNAMMDLQEGALMLLGPtMNAKvafeL 298
Cdd:PRK07811 175 AGAKVVVDNTFaSPYLQQPLALGADVVVHSTTKYIGGHSDVVGGAlVTNDEELDEAFAFLQNGAGAVPGP-FDAY----L 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 299 SER-LPHLPLRMQEHSRRAAEYASRM-RRLGL-RVAYPGLPDHPHHArlLAiANPGYGAGGMLCVDM-GTEDRANRLMhh 374
Cdd:PRK07811 250 TLRgLKTLAVRMDRHSENAEAVAEFLaGHPEVsTVLYPGLPSHPGHE--VA-ARQMRGFGGMVSVRLaGGEEAARDFC-- 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1002302115 375 lqNTTRFGLMAVSLGYYETLMscsgsstssEMPPE-DRARAGISP-----GLVRMSVG 426
Cdd:PRK07811 325 --ARTKVFTLAESLGGVESLI---------EHPSAmTHASTAGSQlevpdDLVRLSVG 371
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
59-426 |
7.53e-66 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 216.98 E-value: 7.53e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 59 EHGGVNMSIEASATFTVMEPDTMRRLFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLM 138
Cdd:PRK07503 24 HGGALVPPVYLTATFAFPTAEYGAECFAGE---EEG--HFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAITATLW 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 139 QLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVA 218
Cdd:PRK07503 99 TLLRPGDEVIVDQTLYGCTFAFLHHGLGEF-GVTVRHVDLTDPAALKAAISD-KTRMVYFETPANPNMRLVDIAAVAEIA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 219 HDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMdlQEGALMLLGPTMNAKVAFE 297
Cdd:PRK07503 177 HGAGAKVVVDNTYcTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIR--LEGLKDMTGAVMSPFDAFL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 298 LSERLPHLPLRMQEHSRRA---AEYASRMRRLGLrVAYPGLPDHPHHArlLAIANPGYGaGGMLCVDM-GTEDRANRLMH 373
Cdd:PRK07503 255 LMRGLKTLALRMDRHCASAqavAEWLARHPAVEL-VHYPGLPSFAQHA--LAQRQMALP-GGMIAFELkGGIAAGRRFMN 330
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1002302115 374 HLQNTTRfglmAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK07503 331 ALQLFAR----AVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVG 379
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
58-443 |
5.92e-65 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 214.25 E-value: 5.92e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 58 GEHGGVNMSIEASATFTVMEPDTMRRlfsgelgpergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVL 137
Cdd:PRK08064 20 KQTGAVNVPIYHASTFHQFDFDTFGK-------------YDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 138 MqLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARV 217
Cdd:PRK08064 87 L-LLSKGDHVLISEDVYGGTYRMITEVLSRF-GIEHTFVDMTNLEEVAQNIKP-NTKLFYVETPSNPLLKVTDIRGVVKL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 218 AHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAG-AICGPASLVNAMMDLQEGALMLLGPtmnaKVA 295
Cdd:PRK08064 164 AKAIGCLTFVDNTFlTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGlAVVKDEELAQKLYFLQNSFGAVLGV----QDC 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 296 FELSERLPHLPLRMQEHSRRAAEYASRMRRLG--LRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDRANRLMH 373
Cdd:PRK08064 240 WLVLRGLKTLHVRLEHSSETANKIALYLQEHPkvQNVYYPGLQTHLGFDIQQSQAT---SAGAVLSFTLQSEEAVRQFVS 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 374 HLqnttRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNgTLEQRWAQFERALS 443
Cdd:PRK08064 317 HV----KLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLE-NVDDLIADFEQALS 381
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
59-445 |
6.81e-63 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 209.16 E-value: 6.81e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 59 EHGGVNMSIEASATFTVMEPDTMRRLFSGELGPergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLM 138
Cdd:PRK05939 6 EHGAVHKPIHTSVTYGYEDARDLIDVFQGKKPG-----FTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 139 QLVGAGGHVVASRCLYGGTHALLSRFlpRASGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVA 218
Cdd:PRK05939 81 TLLRAGDHLVSSQFLFGNTNSLFGTL--RGLGVEVTMVDATDVQNVAAAIRP-NTRMVFVETIANPGTQVADLAGIGALC 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 219 HDAGAKLVVDNTFT-PMVVSPARLGADVVVHSVSKFISGGADIIAGAICGP-----ASLVN-------------AMMDLQ 279
Cdd:PRK05939 158 RERGLLYVVDNTMTsPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTDTglfdwSAYPNifpayrkgdpqqwGLTQIR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 280 EGALMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLGlRVAYPGLPDHPHHARLLAIANpgyGAGG 356
Cdd:PRK05939 238 KKGLRDMGATLSSEAAHRIAIGAETLALRVDRSCSNAlalAQFLEAHPKVA-RVYYPGLASHPQHARATELFR---HYGG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 357 MLCVDMGTEDRANRLMHHLQnttrFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNGTlEQRWA 436
Cdd:PRK05939 314 LLSFELADGIDCFDFLNRLK----LVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDE-ADLIA 388
|
....*....
gi 1002302115 437 QFERALSLM 445
Cdd:PRK05939 389 DFEQALDAT 397
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
97-426 |
7.46e-61 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 204.59 E-value: 7.46e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFV 176
Cdd:PRK08134 56 HVYSRISNPTVAVLEERVAALEGGVGAIATASGQAALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRF-GIETTFV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK08134 135 KPGDIDGWRAAIRP-NTRLLFGETLGNPGLEVLDIPTVAAIAHEAGVPLLVDSTFtTPYLLRPFEHGADLVYHSATKFLG 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAI-----------------CGPASLVNAMMDLQE---GALML---------LGPTMNAKVAFELSERLPHLP 306
Cdd:PRK08134 214 GHGTAIGGVLvdggrfdweasgkfpelTEPYAGFHGMVFAEEstvAAFLLrarreglrdFGACLSPMNAWQLLQGIETLP 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 307 LRMQEH---SRRAAEYASRMRRLGlRVAYPGLPDHPHHA---RLLAianpgYGAGGMLCVDMgTEDRAN--------RLM 372
Cdd:PRK08134 294 LRMERHvanTRKVVAFLASHPAVA-RVAHPELESHPDHAlakRLLP-----RGAGSVFSFDL-KGGRAAgrkfieslKLF 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1002302115 373 HHLQNttrfglmavsLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08134 367 SHLAN----------VGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLSIG 410
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
97-426 |
6.91e-60 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 201.14 E-value: 6.91e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRaSGVRATFV 176
Cdd:PRK07504 57 FIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPR-YGIESTLV 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK07504 136 DGLDLDNWEKAVRP-NTKVFFLESPTNPTLEVIDIAAVAKIANQAGAKLVVDNVFaTPLFQKPLELGAHIVVYSATKHID 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAICGPASLVnammdlQEGALMLL---GPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLG--LRV 330
Cdd:PRK07504 215 GQGRCLGGVVLSDKAWI------EEHLQDYFrhtGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPkvARV 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 331 AYPGLPDHPHHArllAIANPGYGAGGMLCVDM-GTEDRANRlmhhLQNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPE 409
Cdd:PRK07504 289 IYPGRADHPQAD---IIAKQMTGGSTLVAFELkGGKEAAFR----FLNALKIVRISNNLGDAKSLITHPATTTHKNLSPE 361
|
330
....*....|....*..
gi 1002302115 410 DRARAGISPGLVRMSVG 426
Cdd:PRK07504 362 ARAELGISEGFLRLSAG 378
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
55-442 |
7.53e-59 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 198.14 E-value: 7.53e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 55 HEFGEH-GGVNMSIEASATFTVMEPDTMRRLFSGElgpERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAI 133
Cdd:PRK06767 15 YTSEEHkGSLTPPLFQTSTFTFETAQQGEASFAGV---DPS--YIYSRLGNPTVKLFEERMAVLEGGEEALAFGSGMAAI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 134 SSVLMQLVGAGGHVVASRCLYGGTHALLSrFLPRASGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPM 213
Cdd:PRK06767 90 SATLIGFLKAGDHIICSNGLYGCTYGFLE-VLEEKFMITHSFCDMETEADIENKIRP-NTKLIFVETPINPTMKLIDLKQ 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 214 LARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAG-AICGPASLVNAMMDLQEGalmlLGPTMN 291
Cdd:PRK06767 168 VIRVAKRNGLLVIVDNTFcSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGvTICKTRALAEKIRPMRKD----IGGIMA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 292 AKVAFELSERLPHLPLRMQEHSRRAAEYASRMrRLGLRVAYPGLPDHPHHARLLAIanpgygAGGMLCVDM-GTEDRANR 370
Cdd:PRK06767 244 PFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFL-KNHDAVEGVWYPEGELASRQMKR------GGGVISFSIkGGKEETQA 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002302115 371 LMHHLqnttRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNgTLEQRWAQFERAL 442
Cdd:PRK06767 317 FINDL----HFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLE-SWEDIVSDLEQAL 383
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
56-426 |
8.54e-58 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 195.05 E-value: 8.54e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 56 EFGEHGGVNMSIEASATFTVmePDtmrrlfSGELGPergdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISs 135
Cdd:TIGR01329 11 KNDPYDASSMPIYQTATFKQ--PL------AIENGP-----YDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALD- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 136 VLMQLVGAGGHVVASRCLYGGTHALLSRFLPRaSGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLA 215
Cdd:TIGR01329 77 VITRLLNNGDEIIAGDDLYGGTDRLLTQVVPR-SGVVVVHVDTTDLDKVKAALGP-KTKLVLLESPTNPLQKIVDIRKIS 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 216 RVAHDAGAKLVVDNT-FTPMVVSPARLGADVVVHSVSKFISGGADIIAGAIC--GPAsLVNAMMDLQEGALMLLGPTMna 292
Cdd:TIGR01329 155 EMAHAQNALVVVDNTmMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAvkGEE-IAKKVYFLQNSTGSGLAPFD-- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 293 kvAFELSERLPHLPLRM---QEHSRRAAEYASRMRRLgLRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDRAN 369
Cdd:TIGR01329 232 --CWLLLRGIKTLAIRIekqQENARAIAMFLSTHPRV-KKVRYAGLPSHPGFHLHFSQAK---GAGSVLSFETGSVALSK 305
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1002302115 370 RLMhhlqNTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:TIGR01329 306 RLV----EATKLFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVG 358
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
83-443 |
1.26e-57 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 195.34 E-value: 1.26e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 83 RLFSGELgpergDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLS 162
Cdd:PRK07810 53 AAFTGEL-----DRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVFTALGALLGAGDRLVAARSLFGSCFVVCN 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 163 RFLPRAsGVRATFVDADDEAAVRAAV-RPgeTRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPAR 240
Cdd:PRK07810 128 EILPRW-GVETVFVDGEDLSQWEEALsVP--TQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFaTPLLQRGLP 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 241 LGADVVVHSVSKFISGGADIIAGAICGPASLVnammdlqEGALMLL----GPTMNAKVAFELSERLPHLPLRMQEHSRRA 316
Cdd:PRK07810 205 LGADVVVYSGTKHIDGQGRVLGGAILGDREYI-------DGPVQKLmrhtGPALSAFNAWVLLKGLETLALRVRHSNASA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 317 AEYASRMRRL-GLR-VAYPGLPDHPHHArlLAIANPGyGAGGMLCVDM-GTEDRANRLMHHLQNTTRFGLMAVSLGYYET 393
Cdd:PRK07810 278 LRIAEFLEGHpAVRwVRYPFLPSHPQYD--LAKRQMS-GGGTVVTFELdAPEDAAKKRAFEVLDKLRVIDISNNLGDAKS 354
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1002302115 394 LMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNGTlEQRWAQFERALS 443
Cdd:PRK07810 355 LITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDT-DDLIADLDRALG 403
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
98-429 |
1.23e-56 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 193.81 E-value: 1.23e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 98 IYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFV- 176
Cdd:PRK07812 62 IYTRIMNPTQDVVEQRIAALEGGVAALLLASGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKL-GIEVSFVe 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK07812 141 DPDDLDAWRAAVRP-NTKAFFAETISNPQIDVLDIPGVAEVAHEAGVPLIVDNTIaTPYLIRPLEHGADIVVHSATKYLG 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAIC------------------GPASLVNAMMDLQEGALML---------LGPTMNAKVAFELSERLPHLPLR 308
Cdd:PRK07812 220 GHGTAIAGVIVdggtfdwtqgrfpgfttpDPSYHGVVFAELGPPAYALkarvqllrdLGSAISPFNAFLIAQGLETLSLR 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 309 MQEHSRRAAEYAS--RMRRLGLRVAYPGLPDHPHHARLLAIANPGYGA-------GGmlcVDMGTE-DRANRLMHHLQNt 378
Cdd:PRK07812 300 IERHVANAQRVAEflEARDEVASVNYAGLPSSPWYERAKRLAPKGTGAvlsfelaGG---VEAGKAfVNALTLHSHVAN- 375
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1002302115 379 trfglmavsLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNG 429
Cdd:PRK07812 376 ---------IGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEG 417
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
91-426 |
2.24e-55 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 188.89 E-value: 2.24e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 91 PErGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLpRASG 170
Cdd:PRK06460 32 PE-GEKYRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKPGNSVLVHRDMFGRSYRFFTDYL-KNWG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 171 VRATFVDADDEAAVRAAVRPGeTRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHS 249
Cdd:PRK06460 110 VNVDASNPGSDNIIEKAKSKR-YDVVFVENITNPLLRVVDITELSKVCKENGSILIVDATFsTPINQKPLELGADIVVHS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 250 VSKFISGGADIIAGAICGPASLVNAMMDLQEGalmlLGPTMNAKVAFeLSER-LPHLPLRMQEHSRRA---AEYASRMRR 325
Cdd:PRK06460 189 ASKFLAGHNDVIAGLAAGYGKLLNVIDQMRRT----LGTSLDPHAAY-LTLRgIKTLKIRMDVINRNAeqiAEFLEGHPK 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 326 LGlRVAYPGLPDHPHHA---RLLAianpgyGAGGMLCVDM-GTEDRANRLMhhlqNTTRFGLMAVSLGYYETLMSCSGSS 401
Cdd:PRK06460 264 VV-KVYYPGLKSHVDYEiarRVLK------GFGGVLSFEVnGGQESALKVM----KSLKLIIPAQTLGGVNSVISHPATM 332
|
330 340
....*....|....*....|....*
gi 1002302115 402 TSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK06460 333 SHRTLSLEERKIVGITDSLLRLSVG 357
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
73-443 |
2.82e-55 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 188.75 E-value: 2.82e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 73 FTVMEPDTMRRLFSGelgpeRGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRC 152
Cdd:PRK05968 36 FTFDSYDEMEDVYAG-----EKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISSTVLSFVEPGDRIVAVRH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 153 LYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVrPGeTRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF- 231
Cdd:PRK05968 111 VYPDAFRLFETILKRM-GVEVDYVDGRDEEAVAKAL-PG-AKLLYLESPTSWVFELQDVAALAALAKRHGVVTMIDNSWa 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 232 TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAmmdLQEGALMLLGPTMNAKVAFELSERLPHLPLRMQE 311
Cdd:PRK05968 188 SPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIAR---INAEAYPYLGAKLSPFEAWLLLRGLRTLPLRMKA 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 312 HSRRAAEYASRMRRLGL--RVAYPGLPDHPhharllaiaNPGY-GAGGMLCVDMGTEDRANRLMHHLQnTTRFGlmaVSL 388
Cdd:PRK05968 265 HEASALEIARRLKAHPVveRVCHPALANHP---------PAGLsGTSGLFSFIFREGIDVRAFADALK-LFRLG---VSW 331
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1002302115 389 GYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVGYNGTlEQRWAQFERALS 443
Cdd:PRK05968 332 GGHESLVVPAEVVLQQKAQPNSAARFGVSPRSVRLHVGLEGT-EALWADLEQALA 385
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
22-426 |
2.56e-51 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 180.22 E-value: 2.56e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 22 DDDNSSNGNGNADGKPKAR-RREADPAAALAAARHEFGEHGGVNMSIEASATFTvmEPDTMrrlfsgELGPergdlYIYS 100
Cdd:PLN02509 62 DVSTSAVVDGVADCLNEMNiKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFK--QPSAI------ENGP-----YDYT 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 101 RHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVlMQLVGAGGHVVASRCLYGGTHALLSRFLPRaSGVRATFVDADD 180
Cdd:PLN02509 129 RSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAV-THLIKNGEEIVAGDDVYGGSDRLLSQVVPR-SGVVVKRVNTTN 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 181 EAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNT-FTPMVVSPARLGADVVVHSVSKFISGGAD 259
Cdd:PLN02509 207 LDEVAAAIGP-QTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSiMSPVLSRPLELGADIVMHSATKFIAGHSD 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 260 IIAG--AICGpASLVNAMMDLQ--EGA--------LMLLG-PTMNAKVAfelserlphlplRMQEHSRRAAEYASRMRRL 326
Cdd:PLN02509 286 VMAGvlAVKG-EKLAKEVYFLQnsEGSglapfdcwLCLRGiKTMALRIE------------KQQENARKIAMYLSSHPRV 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 327 GlRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDranrLMHHLQNTTRFGLMAVSLGYYETLMSCSGSSTSSEM 406
Cdd:PLN02509 353 K-KVYYAGLPDHPGHHLHFSQAK---GAGSVFSFITGSVA----LSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASI 424
|
410 420
....*....|....*....|
gi 1002302115 407 PPEDRARAGISPGLVRMSVG 426
Cdd:PLN02509 425 PAEVREARGLTEDLVRISAG 444
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
97-426 |
6.92e-51 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 176.43 E-value: 6.92e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISsVLMQLVGAGGHVVASRCLYGGTHALLSrFLPRASGVRATFV 176
Cdd:PRK08247 44 FDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQ-LVMSLFRSGDELIVSSDLYGGTYRLFE-EHWKKWNVRFVYV 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK08247 122 NTASLKAIEQAITP-NTKAIFIETPTNPLMQETDIAAIAKIAKKHGLLLIVDNTFyTPVLQRPLEEGADIVIHSATKYLG 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAICGP-ASLVNAMMDLQEGAlmllGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRrlglrvaypg 334
Cdd:PRK08247 201 GHNDVLAGLVVAKgQELCERLAYYQNAA----GAVLSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLN---------- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 335 lpDHPHHARLLaianpgY-GAGGMLCVDMGTEDRANRLMHHLQNTTrfglMAVSLGYYETLMSCSGSSTSSEMPPEDRAR 413
Cdd:PRK08247 267 --EQPGVTDVL------YpGRGGMLSFRLQDEEWVNPFLKSLKLIT----FAESLGGVESFITYPATQTHADIPEEIRIA 334
|
330
....*....|...
gi 1002302115 414 AGISPGLVRMSVG 426
Cdd:PRK08247 335 NGVCNRLLRFSVG 347
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
97-426 |
3.66e-50 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 175.09 E-value: 3.66e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLmQLVGAGGHVVASRCLYGGTHALLSRFLPrASGVRATFV 176
Cdd:PRK06176 42 YEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVF-SLFQSGDHVLLGDDVYGGTFRLFDKVLV-KNGLSCTII 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK06176 120 DTSDLSQIKKAIKP-NTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFaTPYYQNPLLLGADIVVHSGTKYLG 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAIC-GPASLVNAMMDLQEGALMLLGPtmnaKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLGlRVA 331
Cdd:PRK06176 199 GHSDVVAGLVTtNNEALAQEIAFFQNAIGGVLGP----QDSWLLQRGIKTLGLRMEAHQKNAlcvAEFLEKHPKVE-KVY 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 332 YPGLPDHPHHarllAIANPGY-GAGGMLCVDMGTEDRANRLMHHLqnttRFGLMAVSLGYYETLMSCSGSSTSSEMPPED 410
Cdd:PRK06176 274 YPGLPTHPNH----ELAKKQMrGFSGMLSFTLKNDSEAVAFVESL----KLFILGESLGGVESLVGIPAFMTHACIPKEQ 345
|
330
....*....|....*.
gi 1002302115 411 RARAGISPGLVRMSVG 426
Cdd:PRK06176 346 REAAGIRDGLVRLSVG 361
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
97-426 |
4.17e-49 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 173.49 E-value: 4.17e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 97 YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFV 176
Cdd:PRK08248 56 NIYTRIMNPTTDVFEKRIAALEGGIGALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKL-GITVKFV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRAAVRpGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFIS 255
Cdd:PRK08248 135 DPSDPENFEAAIT-DKTKALFAETIGNPKGDVLDIEAVAAIAHEHGIPLIVDNTFaSPYLLRPIEHGADIVVHSATKFIG 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 256 GGADIIAGAIC--------------------------------GP-ASLVNAMMDLqegaLMLLGPTMNAKVAFELSERL 302
Cdd:PRK08248 214 GHGTSIGGVIVdsgkfdwkgsgkfpgltepdpsyhglvytdavGEaAYITKARVQL----LRDLGAALSPFNSFLLLQGL 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 303 PHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHArlLAIANPGYGAGGMLCVDM-GTEDRANRLMHHLQntt 379
Cdd:PRK08248 290 ETLHLRMERHSENALAVAKFLEEHEAveWVSYPGLPSHPSYE--LAKKYLPKGQGAILTFGIkGGVEAGKKLIDSVK--- 364
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1002302115 380 RFGLMAvSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08248 365 LFSHLA-NVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRLSVG 410
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
93-443 |
1.08e-47 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 168.54 E-value: 1.08e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 93 RGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVR 172
Cdd:PRK06434 52 RGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMGAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTL-GIH 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 173 ATFVDADDEAAVRaaVRPGETRVVYVETMSNPTLAVADIPMLARVAHdaGAKLVVDNTF-TPMVVSPARLGADVVVHSVS 251
Cdd:PRK06434 131 VDYIDTDRLNSLD--FDPSNYDLIYAESITNPTLKVPDIKNVSSFCH--ENDVIVDATFaSPYNQNPLDLGADVVIHSAT 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 252 KFISGGADIIAGAI-CGPASLVNAMMDLQEgalmLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLG--L 328
Cdd:PRK06434 207 KYISGHSDVVMGVAgTNNKSIFNNLVERRK----TLGSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKkiS 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 329 RVAYPGLPDHPHHARllaianpgyGAGGMLCVDMGTEDRANRLMHHLQnttrFGLMAVSLGYYETLMSCSGSSTSSEMPP 408
Cdd:PRK06434 283 NVYYPDTEIGKKVLR---------GFGGMLSFELRSMEDVHKFIRNLE----IPMVAASLGGVESLITLPVETSHSSLSP 349
|
330 340 350
....*....|....*....|....*....|....*
gi 1002302115 409 EDRARAGISPGLVRMSVGYNgTLEQRWAQFERALS 443
Cdd:PRK06434 350 EERERLGISDNLVRFSIGIE-DIDDLIKDIENALS 383
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
99-426 |
9.85e-47 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 166.22 E-value: 9.85e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 99 YSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRASgVRATFVDA 178
Cdd:PRK08045 46 YSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGC-YRVLFVDQ 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 179 DDEAAVRAAVrPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGG 257
Cdd:PRK08045 125 GDEQALRAAL-AEKPKLVLVESPSNPLLRVVDIAKICHLAREAGAVSVVDNTFlSPALQNPLALGADLVLHSCTKYLNGH 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 258 ADIIAGAICgpASLVNAMMDLQEGAlMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGL 335
Cdd:PRK08045 204 SDVVAGVVI--AKDPDVVTELAWWA-NNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLvkKLYHPSL 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 336 PDHPHHaRLLAIANPGYGAggMLCVDM-GTEDRANRLMHHLQNTTrfglMAVSLGYYETLMSCSGSSTSSEMPPEDRARA 414
Cdd:PRK08045 281 PENQGH-EIAARQQKGFGA--MLSFELdGDEQTLRRFLGGLSLFT----LAESLGGVESLISHAATMTHAGMAPEARAAA 353
|
330
....*....|..
gi 1002302115 415 GISPGLVRMSVG 426
Cdd:PRK08045 354 GISETLLRISTG 365
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
98-426 |
5.82e-46 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 164.84 E-value: 5.82e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 98 IYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRAT-FV 176
Cdd:PRK07049 76 VYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNF-GVGAVgFA 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 177 DADDEAAVRA----AVRPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAK------LVVDNTFT-PMVVSPARLGADV 245
Cdd:PRK07049 155 DGLSEAAIGAaaeaAAAKGRVSLILIETPANPTNSLVDVAAVRRVADAIEARqghrpiIACDNTLLgPVFQKPLEHGADL 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 246 VVHSVSKFISGGADIIAGAICGPASLVNAMMDLQeGAlmlLGPTMNAKVAFELSERLPHLPLRMQehsrRAAEYASRMRR 325
Cdd:PRK07049 235 SVYSLTKYVGGHSDLVAGAVLGRKALIRQVRALR-SA---IGTQLDPHSCWMLGRSLETLVLRME----RANRNARAVAE 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 326 LglrvaypgLPDHPHHARL----LAIANPGY---------GAGGMLCVDM-GTEDRANRLMHHLQnttRFGLmAVSLGYY 391
Cdd:PRK07049 307 F--------LRDHPKVEKLhylpFLDPDSAYgavykrqctGAGSTFSFDIkGGQAAAFRFLNALQ---IFKL-AVSLGGT 374
|
330 340 350
....*....|....*....|....*....|....*
gi 1002302115 392 ETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK07049 375 ESLASHPASMTHSGVPADVRERIGVLESTIRLSIG 409
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
98-426 |
1.05e-45 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 164.12 E-value: 1.05e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 98 IYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGG-----THALlsrflpRASGVR 172
Cdd:PRK05994 56 IYTRITNPTNAVLEERVAALEGGTAALAVASGHAAQFLVFHTLLQPGDEFIAARKLYGGsinqfGHAF------KSFGWQ 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 173 ATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVS 251
Cdd:PRK05994 130 VRWADADDPASFERAITP-RTKAIFIESIANPGGTVTDIAAIAEVAHRAGLPLIVDNTLaSPYLIRPIEHGADIVVHSLT 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 252 KFISGGADIIAGAI--CG---------------PASLVNAMMdLQEG-------------ALMLLGPTMNAKVAFELSER 301
Cdd:PRK05994 209 KFLGGHGNSMGGIIvdGGtfdwsksgkypmlsePRPEYHGLV-LHETfgnfafaiaarvlGLRDLGPAISPFNAFLILTG 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 302 LPHLPLRMQEHSRRA---AEYASRMRRLGLrVAYPGLPDHPHHArlLAIANPGYGAGGMLCVDM-GTEDRANRLMHHLQn 377
Cdd:PRK05994 288 IETLPLRMQRHSDNAlavAEWLKGHPKVSW-VNYAGLPDDPYHA--LAQKYSPKGAGAVFTFGLkGGYEAGVKLVSSLK- 363
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1002302115 378 ttRFGLMAvSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK05994 364 --LFSHLA-NIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLSIG 409
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
98-426 |
1.86e-45 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 163.53 E-value: 1.86e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 98 IYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVD 177
Cdd:PRK06084 51 IYTRIMNPTNDVLEQRVAALEGGVGALAVASGMAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRI-GIETRFAA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 178 ADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISG 256
Cdd:PRK06084 130 HDDIAALEALIDE-RTKAVFCESIGNPAGNIIDIQALADAAHRHGVPLIVDNTVaTPVLCRPFEHGADIVVHSLTKYIGG 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 257 GADIIAGAIC---------------------------------GPASLVNAmmdLQEGALMLLGPTMNAKVAFELSERLP 303
Cdd:PRK06084 209 HGTSIGGIVVdsgkfpwaehkerfallntpdpsyhgvtyteafGPAAFIGR---CRVVPLRNMGAALSPFNAFLILQGLE 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 304 HLPLRMQEHSRRA---AEYASRMRRLGLrVAYPGLPDHPHHArlLAIANPGYGAGGMLCVDM-GTEDRANRLMHHLQNTT 379
Cdd:PRK06084 286 TLALRMERHTENAlkvARYLQQHPQVAW-VKYAGLPDHPEHE--LARRYMGGKPASILSFGIkGGQAAGARFIDALKLVV 362
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1002302115 380 RFglmaVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK06084 363 RL----VNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVRLSIG 405
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
60-426 |
9.24e-45 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 161.31 E-value: 9.24e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 60 HGGVNMSIEASATFTvmepdtmrrlFSGeLGPERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQ 139
Cdd:PRK08776 28 YGAVTPPIVLSSNFS----------FDG-FGNKRQ--YDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLVLNA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 140 LVGAGGHVVASRCLYGGTHALLSRFLPRASGVRATFVDADDEAAVRAAVRPgeTRVVYVETMSNPTLAVADIPMLARVAH 219
Cdd:PRK08776 95 LLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQS--PKLVLIETPSNPLLRITDLRFVIEAAH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 220 DAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDLQEGALMLLGPTMNAkvaFEL 298
Cdd:PRK08776 173 KVGALTVVDNTFlSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDA---FLT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 299 SERLPHLPLRMQEHSRRAAEYASRMRRLGL--RVAYPGLPDHPHHArLLAIANPGYGAggMLCVDMGTEDRANRLmhhLQ 376
Cdd:PRK08776 250 LRGLRTLDARLRVHQENADAIAALLDGHAAvnQVYYPGLASHPGHA-LAARQQKGFGA--MLSFELEGGEAAVRA---FV 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1002302115 377 NTTRFGLMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08776 324 DGLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVG 373
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
58-426 |
5.83e-42 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 154.26 E-value: 5.83e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 58 GEHGGVNMSIEASATFTVMEPDTMRRLFSGE-LGPergdlyIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSV 136
Cdd:PRK05613 27 SDTSARNLPIYQTTSYVFDSAEHAKQRFALEdLGP------IYSRLTNPTVEALENRIASLEGGVHAVAFASGQAAETAA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 137 LMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFV-DADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLA 215
Cdd:PRK05613 101 ILNLAGAGDHIVTSPRLYGGTETLFLVTLNRL-GIEVTFVeNPDDPESWQAAVQP-NTKAFFGETFANPQADVLDIPAVA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 216 RVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAIC-----------------------GPASL 271
Cdd:PRK05613 179 EVAHRNQVPLIVDNTIaTAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtverdgkpvfpyfvtpDPAYH 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 272 VNAMMDLQEGALML---------LGPTMNAKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLGlRVAYPGLPDHP 339
Cdd:PRK05613 259 GLKYADLGAPAFGLkaragllrdTGATLSPFNAWVTAQGLDTLSLRLERHNENAikvAEFLNNHEKVA-KVNFAGLKDSP 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 340 HHA--RLLAIANPgygaGGMLCVDM-GTEDRANRLMHHLQNTTRFGlmavSLGYYETLMSCSGSSTSSEMPPEDRARAGI 416
Cdd:PRK05613 338 WYAtkEKLGLKYT----GSVLSFDIkGGKDEAWAFIDALKLHSNLA----NIGDVRSLVVHPATTTHSQSDEAGLARAGI 409
|
410
....*....|
gi 1002302115 417 SPGLVRMSVG 426
Cdd:PRK05613 410 TQATVRLSVG 419
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
88-426 |
3.88e-41 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 150.36 E-value: 3.88e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 88 ELGPERGdlYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISsVLMQLVGAGGHVVASRCLYGGThalLSRFLPR 167
Cdd:PRK07269 39 EFGQSTG--FDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIV-LAFSVFPVGSKVVAVRDLYGGS---FRWFNQQ 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 168 ASGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVV 246
Cdd:PRK07269 113 EKEGRFHFTYANTEEELIAAIEE-DTDIVYIETPTNPLMVEFDIEKVAKLAHAKGAKVIVDNTFySPIYQRPIELGADIV 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 247 VHSVSKFISGGADIIAGAIcgpasLVN--AMMDLQEGALMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMR 324
Cdd:PRK07269 192 LHSATKYLSGHNDVLAGVV-----VTNdlELYEKLFYNLNTTGAVLSPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLK 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 325 RLGL--RVAYPGLpdhphharllaianpgygaGGMLCVDMGTEDRANRLMHHLQNTTrfglMAVSLGYYETLMSCSGSST 402
Cdd:PRK07269 267 KSPAvkEVLYTGK-------------------GGMISFKVADETRIPHILNSLKVFT----FAESLGGVESLITYPTTQT 323
|
330 340
....*....|....*....|....
gi 1002302115 403 SSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK07269 324 HADIPAEVRHSYGLTDDLLRLSIG 347
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
90-443 |
1.02e-39 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 146.68 E-value: 1.02e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 90 GPERGDLYIYSRHFNPTVLALGRQMAALEGTEAAyCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLpRAS 169
Cdd:PRK07582 36 PGEPTGPDTYGRASNPTWRALEAALGELEGAEAL-VFPSGMAAITAVLRALLRPGDTVVVPADGYYQVRALAREYL-APL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 170 GVRATFVDADDEAAVRAAvrpgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVH 248
Cdd:PRK07582 114 GVTVREAPTAGMAEAALA----GADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTaTPLGQRPLELGADLVVA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 249 SVSKFISGGADIIAGAIcgpASLVNAMMDLQEGALMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRMRR--- 325
Cdd:PRK07582 190 SDTKALTGHSDLLLGYV---AGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGhpa 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 326 -LGLRvaYPGLPDHPHHArlLAIANPgYGAGGMLCVDMGTEDRANRLMHHLQ---NTTRFGlmavslGYYETLmscsgss 401
Cdd:PRK07582 267 vRGVR--YPGLPGDPAHE--VAARQM-RRFGGLVSFELADAAAAERFVAASRlvvAATSFG------GVHTSA------- 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1002302115 402 tssemppEDRARAG--ISPGLVRMSVGYNGTlEQRWAQFERALS 443
Cdd:PRK07582 329 -------DRRARWGdaVPEGFVRLSCGIEDT-DDLVADLERALD 364
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
91-426 |
5.13e-37 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 139.64 E-value: 5.13e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 91 PERGDL--YIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALlsrFLPRA 168
Cdd:PRK08861 37 PAFGEVpkYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLWVSALLGPDDLIVAPHDCYGGTYRL---FNTRA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 169 S--GVRATFVDADDEAAVRAAVrPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADV 245
Cdd:PRK08861 114 NkgDFKVQFVDQSDAAALDAAL-AKKPKLILLETPSNPLVRVVDIAELCQKAKAVGALVAVDNTFlTPVLQKPLELGADF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 246 VVHSVSKFISGGADIIAGAIcgpaslvnaMMDLQEGALML------LGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEY 319
Cdd:PRK08861 193 VIHSTTKYINGHSDVIGGVL---------ITKTKEHAEELawwgncIGATGTPFDSYMTLRGIRTLGARMRVHEESAQQI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 320 ASRMRRLGL--RVAYPGLPDHPHHaRLLAIANPGYGAggMLCVDM-GTEDRANRLMHHLQnttRFGLmAVSLGYYETLMS 396
Cdd:PRK08861 264 LAYLQTQSLvgTIYHPSLPEHPGH-EIAKKQQSGFGS--MLSFEFaGSFEQLKVFVKALA---LFSL-AESLGGVESLIC 336
|
330 340 350
....*....|....*....|....*....|
gi 1002302115 397 CSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK08861 337 HPASMTHRAMGEEALAEAGVSQQLLRLSVG 366
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
74-342 |
6.66e-31 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 122.91 E-value: 6.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 74 TVMEPD--TMRrlfsgELGPERGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASR 151
Cdd:PRK07050 37 TVVFPDlaTMR-----ALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKAGDDVLIPD 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 152 CLYgGTHALLSRFLPRASGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF 231
Cdd:PRK07050 112 NAY-GPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQP-NTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTAIDNTY 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 232 TPMVV-SPARLGADVVVHSVSKFISGGADIIAGA-ICGPASLVNAMmdlqEGALMLLGPTMNAKVAFELSERLPHLPLRM 309
Cdd:PRK07050 190 SAGLAfKPFEHGVDISVQALTKYQSGGSDVLMGAtITADAELHAKL----KLARMRLGIGVSADDCSLVLRGLPSLQVRL 265
|
250 260 270
....*....|....*....|....*....|....*
gi 1002302115 310 QEHSRRAAEYAS--RMRRLGLRVAYPGLPDHPHHA 342
Cdd:PRK07050 266 AAHDRSALEVAEwlKARPEIATVLHPALPDCPGHA 300
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
61-394 |
3.37e-30 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 120.75 E-value: 3.37e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 61 GGVNMSIEASATFTVMEPDTMRRlfsgelgpeRGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQL 140
Cdd:TIGR01324 15 GSVNPPLQRASTVLFDSHAAQRR---------AKGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVTNSILAF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 141 VGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHD 220
Cdd:TIGR01324 86 VKAGDHVLMVDSAYEPTRYFCDIVLKRM-GVDITYYDPLIGEDIATLIQP-NTKVLFLEAPSSITFEIQDIPAIAKAARN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 221 AGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDlqegALMLLGPTMNAKVAFELS 299
Cdd:TIGR01324 164 PGIVIMIDNTWaAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVANARTWDQLRE----HSYLMGQMVDADDAYTTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 300 ERLPHLPLRMQEHSRRAAEYASRM--RRLGLRVAYPGLPDHPHHARLLaiaNPGYGAGGMLCVDM--GTEDRANRLMHHL 375
Cdd:TIGR01324 240 RGLRTLGVRLKQHQESSLAIAKWLseQPEVARVLHPALPSCPGHEFWK---RDFSGSSGLFSFVLqrLTQKQVHAFLDHL 316
|
330
....*....|....*....
gi 1002302115 376 QnttRFGlMAVSLGYYETL 394
Cdd:TIGR01324 317 Q---LFG-LGYSWGGYESL 331
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
60-342 |
9.23e-29 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 116.83 E-value: 9.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 60 HGGVNMSI-EASatfTVMEPD--TMRrlfsgelgpERGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSV 136
Cdd:PRK05967 28 HGFVNPPVvHAS---TVLFPDaeTMA---------TRGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 137 LMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLAR 216
Cdd:PRK05967 96 FLGFLSPGDHALIVDSVYYPTRHFCDTMLKRL-GVEVEYYDPEIGAGIAKLMRP-NTKVVHTEAPGSNTFEMQDIPAIAE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 217 VAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASLVNAMMDlqegALMLLGPTMNAKVA 295
Cdd:PRK05967 174 AAHRHGAIVMMDNTWaTPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCWPQLLE----AHGTLGLCAGPDDT 249
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1002302115 296 FELSERLPHLPLRMQEHSRRAAEYASRM--RRLGLRVAYPGLPDHPHHA 342
Cdd:PRK05967 250 YQILRGLRTMGIRLEHHRKSALEIARWLegRPDVARVLHPALPSFPGHE 298
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
70-426 |
7.39e-28 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 115.15 E-value: 7.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 70 SATFTVMEPDTMRRLFSGElgperGDLYIYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVA 149
Cdd:PRK06702 31 STTYKYDTSDDLAALFNLE-----AEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMLAVLNICSSGDHLLC 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 150 SRCLYGGTHALLSRFLpRASGVRATFVDADDEAAVRAAVRPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDN 229
Cdd:PRK06702 106 SSTVYGGTFNLFGVSL-RKLGIDVTFFNPNLTADEIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELEVPFIVDN 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 230 TF-TPMVVSPARLGADVVVHSVSKFISGGADIIAGAICGPASL-------------------VNAMMDLQEGALML---- 285
Cdd:PRK06702 185 TLaTPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIDGGNFdwtngkypelvepdpsyhgVSYVQNFGAAAYIVkarv 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 286 -----LGPTMNAKVAFELSERLPHLPLRMQEHSRRA---AEYASRMRRLGLrVAYPGLPDHPHHArlLAIANPGYGAGGM 357
Cdd:PRK06702 265 qllrdYGNCMSPFNAYISNIGLETLHLRMERHSENAlavAKWLADHERIEW-VNYPGLDSNENYS--LAQKYLKKGASGV 341
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 358 LCVDM-GTEDRANRLMHHLQNTTrfglMAVSLGYYETLMSCSGSSTSSEMPPEDRARAGISPGLVRMSVG 426
Cdd:PRK06702 342 LTFGIkGGLEAAKEFIANVKLAT----LVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVG 407
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
99-320 |
2.32e-19 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 89.79 E-value: 2.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 99 YSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVRATFVDA 178
Cdd:PRK09028 55 YGRRGTPTHFAFQAAIVELEGGAGTALYPSGAAAISNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGF-GIETTYYDP 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 179 DDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTF-TPMVVSPARLGADVVVHSVSKFISGG 257
Cdd:PRK09028 134 MIGEGIRELIRP-NTKVLFLESPGSITMEVQDVPTLSRIAHEHDIVVMLDNTWaSPINSRPFEMGVDISIQAATKYIVGH 212
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002302115 258 ADIIAGAicgpASLVNAMMD-LQEGAlMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYA 320
Cdd:PRK09028 213 SDVMLGT----ATANEKHWDqLREHS-YLMGQCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVA 271
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
93-431 |
1.29e-17 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 84.37 E-value: 1.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 93 RGDLYiYSRHFNPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSRFLPRAsGVR 172
Cdd:PRK08114 51 NGELF-YGRRGTLTHFSLQEAMCELEGGAGCALYPCGAAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKL-GVT 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 173 ATFVDADDEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVV--DNTFTPMVVSPA-RLGADVVVHS 249
Cdd:PRK08114 129 TTWFDPLIGADIAKLIQP-NTKVVFLESPGSITMEVHDVPAIVAAVRSVNPDAVImiDNTWAAGVLFKAlDFGIDISIQA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 250 VSKFISGGADIIAGaicgpASLVNAMM--DLQEGAlMLLGPTMNAKVAFELSERLPHLPLRMQEHSRRAAEYASRM--RR 325
Cdd:PRK08114 208 GTKYLVGHSDAMIG-----TAVANARCweQLRENS-YLMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLaeHP 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 326 LGLRVAYPGLPDHPHHARLLAIANpgyGAGGMLCVDMGTEDRANRLMHHLQNTTRFGlMAVSLGYYETLMSCSGsstsse 405
Cdd:PRK08114 282 EVARVNHPALPGCKGHEFWKRDFT---GSSGLFSFVLKKKLTDEQLANYLDNFSLFS-MAYSWGGFESLILANQ------ 351
|
330 340
....*....|....*....|....*.
gi 1002302115 406 mpPEDRARagISPGLVRmsvGYNGTL 431
Cdd:PRK08114 352 --PEEIAA--IRPAGEV---DFTGTL 370
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
125-393 |
5.57e-08 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 54.56 E-value: 5.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 125 CTASGMSAISSVLMQLVGAGGHVVASrclYGGTHA--LLSRFLPRASGVRATFVDAD-----DEAAVRAAVRPgETRVVY 197
Cdd:pfam00266 69 GTTEAINLVALSLGRSLKPGDEIVIT---EMEHHAnlVPWQELAKRTGARVRVLPLDedgllDLDELEKLITP-KTKLVA 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 198 VETMSNPTLAVADIPMLARVAHDAGAKLVVD--NTFTPMVVSPARLGADVVVHSVSKFIsGGADIiaGAICGPASLVNAM 275
Cdd:pfam00266 145 ITHVSNVTGTIQPVPEIGKLAHQYGALVLVDaaQAIGHRPIDVQKLGVDFLAFSGHKLY-GPTGI--GVLYGRRDLLEKM 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 276 MDLQEGALMLLGPTMNAKVAFELSERL----PHLPL-----------------RMQEHSRRAAEYA-SRMRRLGLRVAYP 333
Cdd:pfam00266 222 PPLLGGGGMIETVSLQESTFADAPWKFeagtPNIAGiiglgaaleylseigleAIEKHEHELAQYLyERLLSLPGIRLYG 301
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002302115 334 GLPDHP--------HHARLLAIANPGYGAG---GMLCvdmgtedrANRLMHHLQNTtrfGLMAVSLGYYET 393
Cdd:pfam00266 302 PERRASiisfnfkgVHPHDVATLLDESGIAvrsGHHC--------AQPLMVRLGLG---GTVRASFYIYNT 361
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
126-333 |
7.45e-07 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 51.19 E-value: 7.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 126 TASGMSAISSVLMQLVGAGGHVVASRCLYGGthallSRFLPRASGVRATFVDADDE-------AAVRAAVRPgETRVVYV 198
Cdd:cd00609 65 TNGAQEALSLLLRALLNPGDEVLVPDPTYPG-----YEAAARLAGAEVVPVPLDEEggflldlELLEAAKTP-KTKLLYL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 199 ETMSNPT---LAVADIPMLARVAHDAGAKLVVDN-----TFTPMVVSPARLGAD----VVVHSVSKFIsGGADIIAGAIC 266
Cdd:cd00609 139 NNPNNPTgavLSEEELEELAELAKKHGILIISDEayaelVYDGEPPPALALLDAyervIVLRSFSKTF-GLPGLRIGYLI 217
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002302115 267 GPASLVNAMMDLQEGALMLLGPTMNAKVAFE-LSERLPHLPLRMQEHSRRAAEYASRMRRLGLRVAYP 333
Cdd:cd00609 218 APPEELLERLKKLLPYTTSGPSTLSQAAAAAaLDDGEEHLEELRERYRRRRDALLEALKELGPLVVVK 285
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
116-267 |
7.23e-05 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 43.14 E-value: 7.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 116 ALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHAllsrFLPRASGVRATFVDADDE-------AAVRAAV 188
Cdd:cd01494 13 LQPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYW----VAAELAGAKPVPVPVDDAgyggldvAILEELK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 189 RPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTFT-----PMVVSPARLGADVVVHSVSKFISGGadiIAG 263
Cdd:cd01494 89 AKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAggaspAPGVLIPEGGADVVTFSLHKNLGGE---GGG 165
|
....
gi 1002302115 264 AICG 267
Cdd:cd01494 166 VVIV 169
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
180-268 |
2.47e-04 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 43.20 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 180 DEAAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVD--NTFTPMVVSPARLGADVVVHSVSKFisgg 257
Cdd:PLN02855 162 DVEQLKELLSE-KTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDacQSVPHMPVDVQTLGADFLVASSHKM---- 236
|
90
....*....|.
gi 1002302115 258 adiiagaiCGP 268
Cdd:PLN02855 237 --------CGP 239
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
163-228 |
4.57e-04 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 42.45 E-value: 4.57e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002302115 163 RFLPRASGVRATFVDADDE-----AAVRAAVRPgETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVD 228
Cdd:cd06453 106 QQLAERTGAKLKVVPVDDDgqldlEALEKLLTE-RTKLVAVTHVSNVLGTINPVKEIGEIAHEAGVPVLVD 175
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
104-339 |
5.90e-04 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 41.78 E-value: 5.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 104 NPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASRclygGTHALLsRFLPRASGvrATFV-----DA 178
Cdd:cd06454 45 SDLHEELEEELAEFHGKEAALVFSSGYAANDGVLSTLAGKGDLIISDS----LNHASI-IDGIRLSG--AKKRifkhnDM 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 179 DD-EAAVRAAVRPGETRVVYVETMSNPTLAVADIPMLARVAHDAGAKLVVDNTFTPMVVSPARLGA----------DVVV 247
Cdd:cd06454 118 EDlEKLLREARRPYGKKLIVTEGVYSMDGDIAPLPELVDLAKKYGAILFVDEAHSVGVYGPHGRGVeefggltddvDIIM 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 248 HSVSKfiSGGAdiIAGAICGPASLVNAMMDLQEGALML--LGPTMNA--KVAFELSERLPHLPLRMQEHSRRAAEyasRM 323
Cdd:cd06454 198 GTLGK--AFGA--VGGYIAGSKELIDYLRSYARGFIFStsLPPAVAAaaLAALEVLQGGPERRERLQENVRYLRR---GL 270
|
250
....*....|....*.
gi 1002302115 324 RRLGLRVayPGLPDHP 339
Cdd:cd06454 271 KELGFPV--GGSPSHI 284
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
124-274 |
1.26e-03 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 40.79 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 124 YCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHALLSrfLPRASGVRATFVDAD-----DEAAVRAAVRPgETRVVYV 198
Cdd:PRK07777 89 LVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIA--MAGAHRVPVPLVPDGrgfalDLDALRAAVTP-RTRALIV 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 199 ETMSNPTLAV---ADIPMLARVA--HDAgakLVV-----------DNTFTPMVVSPARLGADVVVHSVSK-FISGGADIi 261
Cdd:PRK07777 166 NSPHNPTGTVltaAELAAIAELAveHDL---LVItdevyehlvfdGARHLPLATLPGMRERTVTISSAAKtFNVTGWKI- 241
|
170
....*....|...
gi 1002302115 262 aGAICGPASLVNA 274
Cdd:PRK07777 242 -GWACGPAPLIAA 253
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
109-210 |
1.66e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 40.70 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 109 ALGRQMAALEGTEAA----YCTASGMSAISSVLMQLVGAGGHVVASRCLYGGTHAllsrfLPRASGVRATFVDAD----- 179
Cdd:PRK06108 69 ALARYVSRLHGVATPperiAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVA-----APKILGARVVCVPLDfgggg 143
|
90 100 110
....*....|....*....|....*....|....
gi 1002302115 180 ---DEAAVRAAVRPGeTRVVYVETMSNPTLAVAD 210
Cdd:PRK06108 144 wtlDLDRLLAAITPR-TRALFINSPNNPTGWTAS 176
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
141-228 |
1.82e-03 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 40.51 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 141 VGAGGHVVASRCLYggtHA-LLS-RFLPRASGVRATFVDADDE-----AAVRAAVRPGeTRVVYVETMSNPTLAVADIPM 213
Cdd:COG0520 100 LKPGDEILITEMEH---HSnIVPwQELAERTGAEVRVIPLDEDgeldlEALEALLTPR-TKLVAVTHVSNVTGTVNPVKE 175
|
90
....*....|....*
gi 1002302115 214 LARVAHDAGAKLVVD 228
Cdd:COG0520 176 IAALAHAHGALVLVD 190
|
|
| GLY1 |
COG2008 |
Threonine aldolase [Amino acid transport and metabolism]; |
105-333 |
2.06e-03 |
|
Threonine aldolase [Amino acid transport and metabolism];
Pssm-ID: 441611 [Multi-domain] Cd Length: 333 Bit Score: 40.05 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 105 PTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASR----CLY-GGTHALLsrflpraSGVRATFVDAD 179
Cdd:COG2008 35 PTVNRLEERVAELFGKEAALFVPSGTMANQLALRAHTRPGDEVICHEtahiYVDeGGAPEAL-------SGVKLLPVPGE 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 180 DE----AAVRAAVRPG-----ETRVVYVEtmsNPT-----LAVADIPMLARVAHDAGAKLVVD-----NTFTPMVVSPAR 240
Cdd:COG2008 108 DGkltpEDLEAAIRPGdvhfpQPGLVSLE---NTTeggtvYPLEELRAIAAVAREHGLPLHLDgarlfNAAAALGVSLAE 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 241 L--GADVVVHSVSKfiSGGAdiIAGAI-CGPASLVNAMMDL--QEGALM----LLGptmnakVAFE--LSERLPhlplRM 309
Cdd:COG2008 185 ItaGVDSVSFGLTK--GLGA--PGGAVlAGDPEFIEEARRWrkRLGGLMrqagFLA------AQGLaaLEDDLE----RL 250
|
250 260
....*....|....*....|....*
gi 1002302115 310 QEHSRRAAEYASRMRRL-GLRVAYP 333
Cdd:COG2008 251 AEDHAMARRLAEGLAALpGVRVPEP 275
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
104-266 |
2.48e-03 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 39.89 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 104 NPTVLALGRQMAALEGTEAAYCTASGMSAISSVLMQLVGAGGHVVASR----CLY-GGTHALLsrflpraSGVRATFVDA 178
Cdd:pfam01212 31 DPTVNRLEDRVAELFGKEAALFVPSGTAANQLALMAHCQRGDEVICGEpahiHFDeTGGHAEL-------GGVQPRPLDG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002302115 179 D-----DEAAVRAAVRPG------ETRVVYVETMSNPT----LAVADIPMLARVAHDAGAKLVVD-----NTFTPMVVSP 238
Cdd:pfam01212 104 DeagnmDLEDLEAAIREVgadifpPTGLISLENTHNSAggqvVSLENLREIAALAREHGIPVHLDgarfaNAAVALGVIV 183
|
170 180 190
....*....|....*....|....*....|
gi 1002302115 239 ARL--GADVVVHSVSKfiSGGADIiaGAIC 266
Cdd:pfam01212 184 KEItsYADSVTMCLSK--GLGAPV--GSVL 209
|
|
| |
