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Conserved domains on  [gi|1002307675|ref|XP_015617230|]
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peptide chain release factor APG3, chloroplastic [Oryza sativa Japonica Group]

Protein Classification

peptide chain release factor 1( domain architecture ID 11415460)

peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA

Gene Ontology:  GO:0016149

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


:

Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216     1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216    80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216   160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216   240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1002307675 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216   320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216     1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216    80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216   160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216   240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1002307675 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216   320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
prfA PRK00591
peptide chain release factor 1; Validated
 51-408 0e+00

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 522.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  51 EPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEM 130
Cdd:PRK00591    1 KPSMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEEAKEMLEE-ESDPEMREM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 131 IDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKG 210
Cdd:PRK00591   80 AKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 211 GFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVN 290
Cdd:PRK00591  160 GYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVN 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 291 KVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVT 370
Cdd:PRK00591  240 TTDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYDAERQKAQAEEAATRKSQVGSGDRSERIRTYNFPQGRVT 319

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1002307675 371 DHRLKM-NFELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:PRK00591  320 DHRINLtLYKLDEVMEGDLDELIDALIAEDQAEKLAALG 358
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 50-408 2.23e-154

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 440.67  E-value: 2.23e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  50 AEPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKENedDPDMAE 129
Cdd:TIGR00019   1 MKPSLLEKLESLLERYEELEALLSDPEVISDQDKLRKLSKEYSQLEEIVDCYREYQQAQEDIKEAKEILEES--DPEMRE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 130 MIDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEK 209
Cdd:TIGR00019  79 MAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAGTGGDEAAIFAGDLFRMYSRYAESKGWKVEILSANETEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 210 GGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNV 289
Cdd:TIGR00019 159 GGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHTSAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 290 NKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRV 369
Cdd:TIGR00019 239 NTTDSAVRITHLPTGIVVECQDERSQHKNKDKAMKVLRARLYEAEQEKQQAAQASTRKSQVGSGDRSERIRTYNFPQNRV 318

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1002307675 370 TDHRLKMN-FELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:TIGR00019 319 TDHRINLTlYKLDEVLEGDLDELIEALIAEDQAQQLAALS 358
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 62-256 1.08e-83

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 254.23  E-value: 1.08e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  62 EKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLqkenEDDPDMAEMIDSEMESLSNQ 141
Cdd:pfam03462   2 EERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKEL----LEDPELAELAEEELEELEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 142 LEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKG 221
Cdd:pfam03462  78 LEELEEELKLLLLPKDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEISG 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1002307675 222 KQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATV 256
Cdd:pfam03462 158 EGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PCRF smart00937
This domain is found in peptide chain release factors;
120-231 6.08e-40

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 138.36  E-value: 6.08e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLLL-LPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWK 198
Cdd:smart00937   4 EEEEDDEMRELAEEELEELEAELEEELEELLKLLlLPKDPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAERKGWK 83

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1002307675  199 FKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:smart00937  84 VEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
 
Name Accession Description Interval E-value
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 53-408 0e+00

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 523.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  53 YLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMID 132
Cdd:COG0216     1 SMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEEAKELLEE-ESDPEMREMAK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 133 SEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGF 212
Cdd:COG0216    80 EELEELEARLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 213 KTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:COG0216   160 KEVIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDVEINPKDLRIDTFRSSGAGGQHVNTT 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVTDH 372
Cdd:COG0216   240 DSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQVGSGDRSERIRTYNFPQGRVTDH 319

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1002307675 373 RLKMNF-ELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:COG0216   320 RINLTLyKLDEVMEGDLDELIDALIAEDQAEKLAALE 356
prfA PRK00591
peptide chain release factor 1; Validated
 51-408 0e+00

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 522.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  51 EPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEM 130
Cdd:PRK00591    1 KPSMLDKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEEAKEMLEE-ESDPEMREM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 131 IDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKG 210
Cdd:PRK00591   80 AKEELKELEERLEELEEELKILLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 211 GFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNVN 290
Cdd:PRK00591  160 GYKEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEEVEVEINPKDLRIDTFRSSGAGGQHVN 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 291 KVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRVT 370
Cdd:PRK00591  240 TTDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYDAERQKAQAEEAATRKSQVGSGDRSERIRTYNFPQGRVT 319

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1002307675 371 DHRLKM-NFELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:PRK00591  320 DHRINLtLYKLDEVMEGDLDELIDALIAEDQAEKLAALG 358
prfA TIGR00019
peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, ...
 50-408 2.23e-154

peptide chain release factor 1; This model describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. [Protein synthesis, Translation factors]


Pssm-ID: 129130 [Multi-domain]  Cd Length: 360  Bit Score: 440.67  E-value: 2.23e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  50 AEPYLIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKENedDPDMAE 129
Cdd:TIGR00019   1 MKPSLLEKLESLLERYEELEALLSDPEVISDQDKLRKLSKEYSQLEEIVDCYREYQQAQEDIKEAKEILEES--DPEMRE 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 130 MIDSEMESLSNQLEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEK 209
Cdd:TIGR00019  79 MAKEELEELEEKIEELEEQLKVLLLPKDPNDEKNVILEIRAGTGGDEAAIFAGDLFRMYSRYAESKGWKVEILSANETEL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 210 GGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADEVDVVIDPKDIELKTARSGGAGGQNV 289
Cdd:TIGR00019 159 GGYKEVIAEIKGDGVYSRLKFESGVHRVQRVPVTESQGRIHTSAATVAVMPELEEVEVDINPADLRIDTFRSSGAGGQHV 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 290 NKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEKIRTYNYKDNRV 369
Cdd:TIGR00019 239 NTTDSAVRITHLPTGIVVECQDERSQHKNKDKAMKVLRARLYEAEQEKQQAAQASTRKSQVGSGDRSERIRTYNFPQNRV 318

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1002307675 370 TDHRLKMN-FELTGFLMGDIESAVQSCSSMEQKELLEEMA 408
Cdd:TIGR00019 319 TDHRINLTlYKLDEVLEGDLDELIEALIAEDQAQQLAALS 358
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 62-256 1.08e-83

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 254.23  E-value: 1.08e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  62 EKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLqkenEDDPDMAEMIDSEMESLSNQ 141
Cdd:pfam03462   2 EERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKEL----LEDPELAELAEEELEELEKR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 142 LEELEEKLKLLLLPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKG 221
Cdd:pfam03462  78 LEELEEELKLLLLPKDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEISG 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1002307675 222 KQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATV 256
Cdd:pfam03462 158 EGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 54-390 8.54e-69

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 221.96  E-value: 8.54e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  54 LIAKLDSAEKAWKEMSVRLADPDIVSDPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMIDS 133
Cdd:TIGR00020  21 GSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSELLELAVE-EDDEETFNELDA 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 134 EMESLSNQLEELEEKLKLlllpNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFK 213
Cdd:TIGR00020 100 ELKALEKKLAELELRTML----SGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRGFKVEIIDYSEGEEAGIK 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 214 TYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKTARSGGAGGQNVNKV 292
Cdd:TIGR00020 176 SVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDdIDIEIKPEDLRIDTYRASGAGGQHVNKT 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 293 ETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESIRNQRKLQVGTGARSEkIRTYNYKD-NRVTD 371
Cdd:TIGR00020 256 DSAVRITHIPTGIVVQCQNDRSQHKNKDSAMKVLKAKLYELEMEKEQAEKDAKEGEKSEIGWGSQ-IRSYVLHPySMVKD 334

                         330
                  ....*....|....*....
gi 1002307675 372 HRlkmnfelTGFLMGDIES 390
Cdd:TIGR00020 335 LR-------TGYETGNVQA 346
RF-1 pfam00472
RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and ...
 263-373 1.25e-54

RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.


Pssm-ID: 459823 [Multi-domain]  Cd Length: 111  Bit Score: 176.46  E-value: 1.25e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 263 DEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYEIKLREQQESI 342
Cdd:pfam00472   1 DEIEIEIDPKDLRIDTFRSSGAGGQHVNKTDSAVRLTHIPTGIVVKCQDERSQHQNREKALKRLRARLYELEEEKEEEKK 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1002307675 343 RNQRKlQVGTGARSEKIRTYNYKD-NRVTDHR 373
Cdd:pfam00472  81 RRIKS-QVGSGDRSEQIRTYNFKPqSRVKDHR 111
PRK08787 PRK08787
peptide chain release factor 2; Provisional
 120-394 8.05e-52

peptide chain release factor 2; Provisional


Pssm-ID: 136970 [Multi-domain]  Cd Length: 313  Bit Score: 176.39  E-value: 8.05e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLlllpNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKF 199
Cdd:PRK08787   27 ESEQDEDTALAVIADLDKYQAHVEKLEFQRMF----SGQMDGANAFVDIQAGAGGTEAQDWAEILLRMYLRWAESRGWKT 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 200 KPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFESGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKT 278
Cdd:PRK08787  103 ELMEVSGGEVAGIKSATVRIEGEYAYGWLKTEIGVHRLVRKSPFDSDNRRHTSFTSVFVSPEVDDnIEIDINPADLRTDV 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 279 ARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLY--EIKLREQQESIRNQRKLQVGTGArs 356
Cdd:PRK08787  183 YRSSGAGGQHVNKTESAVRITHIPTNTVVACQTGRSQHQNRDNAMKMLAAKLYelEVQKRNAEKDALEATKSDIGWGS-- 260

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1002307675 357 eKIRTYNYKDNRVTDHRLKMNFELT-GFLMGDIESAVQS 394
Cdd:PRK08787  261 -QIRNYVLDQSRIKDLRTGIERSDTqKVLDGDLDEFVEA 298
PRK07342 PRK07342
peptide chain release factor 2; Provisional
 74-362 1.22e-51

peptide chain release factor 2; Provisional


Pssm-ID: 235997 [Multi-domain]  Cd Length: 339  Bit Score: 176.61  E-value: 1.22e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  74 DPDIVSDPSEYQKLAQSVAELDQVVSTYRQFkdcEKQIEETKVLQKENEDDPDMAEMIDSE--MESLSNQLEELEEKLKL 151
Cdd:PRK07342    5 DPSLWNDAQEAQKLMRERQQLDDSINGINHL---EQTLNDNIELIAMGEEEGDKSIVEDAEktIRDLKDEIDRRQIDALL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 152 LLLPndplDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:PRK07342   82 SGEA----DANDTYLEVHAGAGGTESQDWASMLLRMYTRWAERQGRKVEVLEVHDGEEAGIKSATILVKGHNAYGWLKTE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 232 SGVHRVQRVPQTETMGRVHTSTATVAIMPEADE-VDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCT 310
Cdd:PRK07342  158 SGVHRLVRISPYDSNARRHTSFASIWVYPVIDDnIEVDVNESDVRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVQCQ 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002307675 311 EERSQLQNRERAFQLLRAKLYEIKL--REQQESIRNQRKLQVGTGarsEKIRTY 362
Cdd:PRK07342  238 QERSQHKNRAKAWSMLRARLYEEELkkREEATNAAAASKTDIGWG---HQIRSY 288
PRK06746 PRK06746
peptide chain release factor 2; Provisional
 80-373 3.52e-51

peptide chain release factor 2; Provisional


Pssm-ID: 75726 [Multi-domain]  Cd Length: 326  Bit Score: 174.92  E-value: 3.52e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  80 DPSEYQKLAQSVAELDQVVSTYRQFKDCEKQIEETKVLQKEnEDDPDMAEMIDSEMESLSNQLEELEEKLKLlllpNDPL 159
Cdd:PRK06746    9 DQQGAQAVINEANALKDMVGKFRQLDETFENLEITHELLKE-EYDEDLHEELESEVKGLIQEMNEYELQLLL----SDPY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 160 DARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFESGVHRVQR 239
Cdd:PRK06746   84 DKNNAILELHPGAGGTESQDWGSMLLRMYTRWAEKRGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 240 VPQTETMGRVHTSTATVAIMPE-ADEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQN 318
Cdd:PRK06746  164 ISPFDSSGRRHTSFVSCEVVPEfNDEVEIEVRTEDLKIDTYRASGAGGQHVNTTDSAVRITHTPTNTVVTCQSERSQIKN 243

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1002307675 319 RERAFQLLRAKLYEIKLREQQ---ESIRNQRKlQVGTGArseKIRTYNYKD-NRVTDHR 373
Cdd:PRK06746  244 REHAMKMLKAKLYQKKLEEQQaelDEIRGEQK-EIGWGS---QIRSYVFHPySLVKDHR 298
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 74-389 1.15e-48

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 168.06  E-value: 1.15e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  74 DPDIVSDPSEYQKLAQSVAELDQVVSTYRQFkdcEKQIEETKVLQK-ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLL 152
Cdd:PRK05589    3 EPNFWNDIKEAQEITSEEKYLKDKLDKYNHL---RNRIEDIEVLCEmMSEEDDEMKKEIISEVKNIKEEIDRFKIETLLS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 153 LLpndpLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWKFKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFES 232
Cdd:PRK05589   80 GE----YDRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 233 GVHRVQRVPQTETMGRVHTSTATVAIMPE-ADEVDVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTE 311
Cdd:PRK05589  156 GIHRLVRISPFNANGKRQTSFASVEVLPElTDDQDIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQCQN 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 312 ERSQLQNRERAFQLLRAKLYEIKLREQQESIRN---QRKlQVGTGArseKIRTYNYKD-NRVTDHRLKM-NFELTGFLMG 386
Cdd:PRK05589  236 ERSQHSNKETAMKMLKSKLVELKERAHKEKIEDltgELK-DMGWGS---QIRSYVFHPyNLVKDHRTGVeTSNVDSVMDG 311


                  ...
gi 1002307675 387 DIE 389
Cdd:PRK05589  312 DID 314
PCRF smart00937
This domain is found in peptide chain release factors;
120-231 6.08e-40

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 138.36  E-value: 6.08e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675  120 ENEDDPDMAEMIDSEMESLSNQLEELEEKLKLLL-LPNDPLDARNILLEVRAGAGGDEAGIWAGDLVRMYQKYCERNSWK 198
Cdd:smart00937   4 EEEEDDEMRELAEEELEELEAELEEELEELLKLLlLPKDPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAERKGWK 83

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1002307675  199 FKPVSSSEAEKGGFKTYVMEVKGKQVYSKLKFE 231
Cdd:smart00937  84 VEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
PrfB COG1186
Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein ...
 266-373 4.12e-30

Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein chain release factor PrfB is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440799 [Multi-domain]  Cd Length: 140  Bit Score: 113.30  E-value: 4.12e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 266 DVVIDPKDIELKTARSGGAGGQNVNKVETAVDLIHK------------PTGIRIFCTEERSQLQNRERAFQLLRAKLYEI 333
Cdd:COG1186    20 EIEIPESDLRIDTYRASGAGGQNVNKVSSAVRLTHDiassslpdsrltPGGIVVKAQEERSQHQNREDALKRLKALLYEA 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1002307675 334 KLREQQEsiRNQRKLQVGTGARSE--KIRtynykdNRVTDHR 373
Cdd:COG1186   100 ELEPKER--RATKPTRGSKKRRLWgkQIR------SMVKDLR 133
release_prfH TIGR03072
putative peptide chain release factor H; Members of this protein family are bacterial proteins ...
 271-366 2.79e-15

putative peptide chain release factor H; Members of this protein family are bacterial proteins homologous to peptide chain release factors 1 (RF-1, product of the prfA gene), and 2 (RF-2, product of the prfB gene). The member from Escherichia coli K-12, designated prfH, appears to be a pseudogene. This class I release factor is always found as the downstream gene of a two-gene operon. [Protein synthesis, Translation factors]


Pssm-ID: 213768  Cd Length: 200  Bit Score: 74.04  E-value: 2.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 271 PKDIELKTARSGGAGGQNVNKVETAVDLIHKPTGIRIFCTEERSQLQNRERAFQLLRAKLYeiKLREQQESI-RNQRKLQ 349
Cdd:TIGR03072 105 EDEIRFETLRSSGPGGQHVNKTESAVRATHLASGISVKVQSERSQHANKRLATLLLAVRLA--DLQQEQAAAlRAERRTA 182

                          90
                  ....*....|....*..
gi 1002307675 350 VGTGARSEKIRTYNYKD 366
Cdd:TIGR03072 183 HHQIERGNPVRVFKGEL 199
PRK09256 PRK09256
aminoacyl-tRNA hydrolase;
266-337 1.98e-13

aminoacyl-tRNA hydrolase;


Pssm-ID: 181730 [Multi-domain]  Cd Length: 138  Bit Score: 67.10  E-value: 1.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002307675 266 DVVIDPKDIELKTARSGGAGGQNVNKVETAVDLI---------------------HKPTG---IRIFCTEERSQLQNRER 321
Cdd:PRK09256    7 RLVIPENELEWRFIRASGPGGQNVNKVSTAVELRfdiaasslpefykerllalagHRITKdgvIVIKAQEFRSQERNRED 86

                          90
                  ....*....|....*.
gi 1002307675 322 AfqllRAKLYEIkLRE 337
Cdd:PRK09256   87 A----LERLVAL-IRE 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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