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Conserved domains on  [gi|1002309591|ref|XP_015618159|]
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disease resistance protein RGA4-like [Oryza sativa Japonica Group]

Protein Classification

NB-LRR family disease resistance protein( domain architecture ID 1001114)

NB-LRR (nucleotide-binding-leucine rich repeat) family disease resistance protein guards the plant against pathogens via an indirect interaction with an avirulence protein contained in the plant, triggering a defense response that restricts the pathogen growth

CATH:  3.80.10.10
Gene Ontology:  GO:0006952|GO:0005515|GO:0000166
PubMed:  20483655|25825425|9545207|21459033|11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NB-ARC super family cl26397
NB-ARC domain;
183-396 6.83e-24

NB-ARC domain;


The actual alignment was detected with superfamily member pfam00931:

Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 102.07  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  183 EKPIEHLVQLLDEagaGGGPQqlrVIAIVGFRGSGKTTLARAVYSRS---GRQFRERAWVDASRWTDVGDLLADIVRQVC 259
Cdd:pfam00931    2 EDMVEKVIGKLSE---KDEPG---IVGIHGMGGVGKTTLAAQIFNDFdevEGHFDSVAWVVVSKTFTISTLQQTILQNLG 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  260 LGEYDVSESHE----ENLRNRLKNKRYLIVLDDI-SMEQWNAIESIFENNGRGSRVIVTTAILSVANsctayksganggc 334
Cdd:pfam00931   76 LSEDDWDNKEEgelaRKIRRALLTKRFLLVLDDVwDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAG------------- 142

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002309591  335 cirRHGCVY-KMQT--LGEAHAKEL---ALGGGSDQRPPELEHGSATLMAKCDGLPLALVSVANHLRC 396
Cdd:pfam00931  143 ---RVGGPSdPHEVelLEPDEAWELfenKVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSC 207
RX-CC_like super family cl36576
Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato ...
 6-138 2.16e-10

Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato virus X resistance protein (RX) confers resistance against potato virus X. It is a member of a family of resistance proteins with a domain architecture that includes an N-terminal coiled-coil domain (modeled here), a nucleotide-binding domain, and leucine-rich repeats (CC-NB-LRR). These intracellular resistance proteins recognize pathogen effector proteins and will subsequently trigger a response that may be as severe as localized cell death. The N-terminal coiled-coil domain of RX has been shown to interact with RanGAP2, which is a necessary co-factor in the resistance response.


The actual alignment was detected with superfamily member cd14798:

Pssm-ID: 453100 [Multi-domain]  Cd Length: 124  Bit Score: 59.17  E-value: 2.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591    6 ATAFTKCVVGKLLEVLDTRYKMLRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPaaerptaVLRAYTELMRELTHDMED 85
Cdd:cd14798      1 AEAAVSFLLEKLGELLEQEADLLSGVKEEIESLKDELESMQAFLKDADAKQDEDE-------ELKDWVKQVRDVAYDAED 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1002309591   86 SIERFLHRVAPRDDHGGagapsWPRRAARWVATLRTRLRFAAEIRKLKTRLED 138
Cdd:cd14798     74 IIDSFLLKLVPDKRRGG-----FLKRLFSLLKELKELHQVAKEIQSIKSRIKD 121
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
576-688 5.94e-05

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 46.85  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  576 NTTTAALSTTDLSCVRSLTVFGDGGDAVSNLRKCKLLRVLDLEQCTtalsddhlaDICKLWNLRYLSIGmSSNVTMLPDN 655
Cdd:COG4886     62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLS-GNQLTDLPEE 131

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1002309591  656 IRRLKLLETIHLSKTKVTMLPLQVVGLPCLAHL 688
Cdd:COG4886    132 LANLTNLKELDLSNNQLTDLPEPLGNLTNLKSL 164
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
183-396 6.83e-24

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 102.07  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  183 EKPIEHLVQLLDEagaGGGPQqlrVIAIVGFRGSGKTTLARAVYSRS---GRQFRERAWVDASRWTDVGDLLADIVRQVC 259
Cdd:pfam00931    2 EDMVEKVIGKLSE---KDEPG---IVGIHGMGGVGKTTLAAQIFNDFdevEGHFDSVAWVVVSKTFTISTLQQTILQNLG 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  260 LGEYDVSESHE----ENLRNRLKNKRYLIVLDDI-SMEQWNAIESIFENNGRGSRVIVTTAILSVANsctayksganggc 334
Cdd:pfam00931   76 LSEDDWDNKEEgelaRKIRRALLTKRFLLVLDDVwDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAG------------- 142

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002309591  335 cirRHGCVY-KMQT--LGEAHAKEL---ALGGGSDQRPPELEHGSATLMAKCDGLPLALVSVANHLRC 396
Cdd:pfam00931  143 ---RVGGPSdPHEVelLEPDEAWELfenKVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSC 207
RX-CC_like cd14798
Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato ...
 6-138 2.16e-10

Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato virus X resistance protein (RX) confers resistance against potato virus X. It is a member of a family of resistance proteins with a domain architecture that includes an N-terminal coiled-coil domain (modeled here), a nucleotide-binding domain, and leucine-rich repeats (CC-NB-LRR). These intracellular resistance proteins recognize pathogen effector proteins and will subsequently trigger a response that may be as severe as localized cell death. The N-terminal coiled-coil domain of RX has been shown to interact with RanGAP2, which is a necessary co-factor in the resistance response.


Pssm-ID: 271353 [Multi-domain]  Cd Length: 124  Bit Score: 59.17  E-value: 2.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591    6 ATAFTKCVVGKLLEVLDTRYKMLRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPaaerptaVLRAYTELMRELTHDMED 85
Cdd:cd14798      1 AEAAVSFLLEKLGELLEQEADLLSGVKEEIESLKDELESMQAFLKDADAKQDEDE-------ELKDWVKQVRDVAYDAED 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1002309591   86 SIERFLHRVAPRDDHGGagapsWPRRAARWVATLRTRLRFAAEIRKLKTRLED 138
Cdd:cd14798     74 IIDSFLLKLVPDKRRGG-----FLKRLFSLLKELKELHQVAKEIQSIKSRIKD 121
COG3903 COG3903
Predicted ATPase [General function prediction only];
41-287 2.06e-09

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 61.96  E-value: 2.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   41 DLLLLAAFMDDQLRRSSSSPAAERPTAVLRAYTELMRELTHDMEDSIERFLHRVAPRDDHGGAGAPSWPRRAARWVATLR 120
Cdd:COG3903     15 ALALLALAAAAAAAAAAAALAAALEALRAALALLLLLLAALALALAALALLLAAAALLLRLLLLLLAARLLARLAAAAAA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  121 TRLRFAAEIRKLKTRLEDETKRLRNAVEAAAAAGGGGHSSATPALAAAAPRGGHVEPNPVGmekPIEHLVQLLDEAGAGG 200
Cdd:COG3903     95 ALARAAAAALALLLRLRLAARRLLLARALAAAALAAAAAAAAAAAAAPAPPPPAPPPPAPL---AALARRAAALAAAARA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  201 GPQQLRVIAIVGFRGSGKTTLARAVYSRSGRQFRERAW-VDASRWTDVGDLLADIVRQVCLGEyDVSESHEENLRNRLKN 279
Cdd:COG3903    172 LLSAARLVTLTGPGGVGKTRLALEVAHRLADRFPDGVWfVDLAGVTDPALVLAAVARALGVRD-APGRDPAARLRAALAD 250


                   ....*...
gi 1002309591  280 KRYLIVLD 287
Cdd:COG3903    251 RRLLLVLD 258
Rx_N pfam18052
Rx N-terminal domain; This entry represents the N-terminal domain found in many plant ...
 13-102 1.01e-08

Rx N-terminal domain; This entry represents the N-terminal domain found in many plant resistance proteins. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold.


Pssm-ID: 436239  Cd Length: 93  Bit Score: 53.43  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   13 VVGKLLEVLDTRYKMLRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPAaerptavLRAYTELMRELTHDMEDSIERFLH 92
Cdd:pfam18052    5 LLEKLGSLLAEEAKLLKGVKDDLEKLKDELESIQAFLEDAERKQITDEQ-------VKLWLKQLRDVAYDAEDVLDEFLY 77

                           90
                   ....*....|
gi 1002309591   93 RVAPRDDHGG 102
Cdd:pfam18052   78 EALRRKSSPK 87
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 180-314 1.07e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 59.50  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  180 VGMEKPIEHLVQLLDEAGagggpQQLRVIAIVGFRGSGKTTLARAVYSRSGRQFRERAWVD---ASRWTDV--------- 247
Cdd:PLN03210   187 VGIEDHIAKMSSLLHLES-----EEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafISKSMEIyssanpddy 261

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002309591  248 -------GDLLADIvrqvcLGEYDVSESHEENLRNRLKNKRYLIVLDDISMEQ-WNAIESIFENNGRGSRVIVTT 314
Cdd:PLN03210   262 nmklhlqRAFLSEI-----LDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDvLDALAGQTQWFGSGSRIIVIT 331
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
576-688 5.94e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 46.85  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  576 NTTTAALSTTDLSCVRSLTVFGDGGDAVSNLRKCKLLRVLDLEQCTtalsddhlaDICKLWNLRYLSIGmSSNVTMLPDN 655
Cdd:COG4886     62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLS-GNQLTDLPEE 131

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1002309591  656 IRRLKLLETIHLSKTKVTMLPLQVVGLPCLAHL 688
Cdd:COG4886    132 LANLTNLKELDLSNNQLTDLPEPLGNLTNLKSL 164
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 206-291 1.85e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 42.75  E-value: 1.85e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   206 RVIAIVGFRGSGKTTLARAVYSRSGRQFRERAWVDASRWTDVGDLLADIVRQVCLGEYDVSESHEENLRNRLKNKRY-LI 284
Cdd:smart00382    3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPdVL 82


                    ....*..
gi 1002309591   285 VLDDISM 291
Cdd:smart00382   83 ILDEITS 89
COG3899 COG3899
Predicted ATPase [General function prediction only];
28-232 6.58e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.08  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   28 LRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPAAERPTAVLRAYTELMRELTHDMEDSIERFLHRVAPRDDHGGAGAPS 107
Cdd:COG3899    137 LGLLLGGLLLAALAALLALAALAAAAAAAAAAAAARAARLRRARAARLAALALRALLLLVLLLLLLLLLLGLLLAAAAAL 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  108 WPRRAARWVATLRTRLRFAAEIRKLKTRLEDETKRLRNAVEAAAAAGGGGHSSATPALAAAAPRGGHVEPNP-VGMEKPI 186
Cdd:COG3899    217 AAAAAAAAAAAPAAPVVLVAALLLALAALLALLLLAARLLGLAGAAALLLLGLLAAAAAGRRLLARRLIPQPlVGREAEL 296

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1002309591  187 EHLVQLLDEAGAGGGpqqlRVIAIVGFRGSGKTTLARAVYSRSGRQ 232
Cdd:COG3899    297 AALLAALERARAGRG----ELVLVSGEAGIGKSRLVRELARRARAR 338
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 208-233 3.50e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 39.08  E-value: 3.50e-03
                           10        20
                   ....*....|....*....|....*.
gi 1002309591  208 IAIVGFRGSGKTTLARAVYSRSGRQF 233
Cdd:cd00464      2 IVLIGMMGAGKTTVGRLLAKALGLPF 27
 
Name Accession Description Interval E-value
NB-ARC pfam00931
NB-ARC domain;
183-396 6.83e-24

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 102.07  E-value: 6.83e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  183 EKPIEHLVQLLDEagaGGGPQqlrVIAIVGFRGSGKTTLARAVYSRS---GRQFRERAWVDASRWTDVGDLLADIVRQVC 259
Cdd:pfam00931    2 EDMVEKVIGKLSE---KDEPG---IVGIHGMGGVGKTTLAAQIFNDFdevEGHFDSVAWVVVSKTFTISTLQQTILQNLG 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  260 LGEYDVSESHE----ENLRNRLKNKRYLIVLDDI-SMEQWNAIESIFENNGRGSRVIVTTAILSVANsctayksganggc 334
Cdd:pfam00931   76 LSEDDWDNKEEgelaRKIRRALLTKRFLLVLDDVwDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAG------------- 142

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002309591  335 cirRHGCVY-KMQT--LGEAHAKEL---ALGGGSDQRPPELEHGSATLMAKCDGLPLALVSVANHLRC 396
Cdd:pfam00931  143 ---RVGGPSdPHEVelLEPDEAWELfenKVFPKTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLSC 207
RX-CC_like cd14798
Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato ...
 6-138 2.16e-10

Coiled-coil domain of the potato virux X resistance protein and similar proteins; The potato virus X resistance protein (RX) confers resistance against potato virus X. It is a member of a family of resistance proteins with a domain architecture that includes an N-terminal coiled-coil domain (modeled here), a nucleotide-binding domain, and leucine-rich repeats (CC-NB-LRR). These intracellular resistance proteins recognize pathogen effector proteins and will subsequently trigger a response that may be as severe as localized cell death. The N-terminal coiled-coil domain of RX has been shown to interact with RanGAP2, which is a necessary co-factor in the resistance response.


Pssm-ID: 271353 [Multi-domain]  Cd Length: 124  Bit Score: 59.17  E-value: 2.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591    6 ATAFTKCVVGKLLEVLDTRYKMLRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPaaerptaVLRAYTELMRELTHDMED 85
Cdd:cd14798      1 AEAAVSFLLEKLGELLEQEADLLSGVKEEIESLKDELESMQAFLKDADAKQDEDE-------ELKDWVKQVRDVAYDAED 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1002309591   86 SIERFLHRVAPRDDHGGagapsWPRRAARWVATLRTRLRFAAEIRKLKTRLED 138
Cdd:cd14798     74 IIDSFLLKLVPDKRRGG-----FLKRLFSLLKELKELHQVAKEIQSIKSRIKD 121
COG3903 COG3903
Predicted ATPase [General function prediction only];
41-287 2.06e-09

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 61.96  E-value: 2.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   41 DLLLLAAFMDDQLRRSSSSPAAERPTAVLRAYTELMRELTHDMEDSIERFLHRVAPRDDHGGAGAPSWPRRAARWVATLR 120
Cdd:COG3903     15 ALALLALAAAAAAAAAAAALAAALEALRAALALLLLLLAALALALAALALLLAAAALLLRLLLLLLAARLLARLAAAAAA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  121 TRLRFAAEIRKLKTRLEDETKRLRNAVEAAAAAGGGGHSSATPALAAAAPRGGHVEPNPVGmekPIEHLVQLLDEAGAGG 200
Cdd:COG3903     95 ALARAAAAALALLLRLRLAARRLLLARALAAAALAAAAAAAAAAAAAPAPPPPAPPPPAPL---AALARRAAALAAAARA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  201 GPQQLRVIAIVGFRGSGKTTLARAVYSRSGRQFRERAW-VDASRWTDVGDLLADIVRQVCLGEyDVSESHEENLRNRLKN 279
Cdd:COG3903    172 LLSAARLVTLTGPGGVGKTRLALEVAHRLADRFPDGVWfVDLAGVTDPALVLAAVARALGVRD-APGRDPAARLRAALAD 250


                   ....*...
gi 1002309591  280 KRYLIVLD 287
Cdd:COG3903    251 RRLLLVLD 258
Rx_N pfam18052
Rx N-terminal domain; This entry represents the N-terminal domain found in many plant ...
 13-102 1.01e-08

Rx N-terminal domain; This entry represents the N-terminal domain found in many plant resistance proteins. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold.


Pssm-ID: 436239  Cd Length: 93  Bit Score: 53.43  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   13 VVGKLLEVLDTRYKMLRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPAaerptavLRAYTELMRELTHDMEDSIERFLH 92
Cdd:pfam18052    5 LLEKLGSLLAEEAKLLKGVKDDLEKLKDELESIQAFLEDAERKQITDEQ-------VKLWLKQLRDVAYDAEDVLDEFLY 77

                           90
                   ....*....|
gi 1002309591   93 RVAPRDDHGG 102
Cdd:pfam18052   78 EALRRKSSPK 87
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 180-314 1.07e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 59.50  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  180 VGMEKPIEHLVQLLDEAGagggpQQLRVIAIVGFRGSGKTTLARAVYSRSGRQFRERAWVD---ASRWTDV--------- 247
Cdd:PLN03210   187 VGIEDHIAKMSSLLHLES-----EEVRMVGIWGSSGIGKTTIARALFSRLSRQFQSSVFIDrafISKSMEIyssanpddy 261

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002309591  248 -------GDLLADIvrqvcLGEYDVSESHEENLRNRLKNKRYLIVLDDISMEQ-WNAIESIFENNGRGSRVIVTT 314
Cdd:PLN03210   262 nmklhlqRAFLSEI-----LDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDvLDALAGQTQWFGSGSRIIVIT 331
AAA_22 pfam13401
AAA domain;
206-312 1.27e-05

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 45.80  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  206 RVIAIVGFRGSGKTTLARAVYSRSGRQFRERAWVDASRWTDVGDLLADIVRQvcLGEYDVSESHEENLRNRL------KN 279
Cdd:pfam13401    6 GILVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPKDLLRALLRA--LGLPLSGRLSKEELLAALqqlllaLA 83

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1002309591  280 KRYLIVLDD---ISMEQWNAIESIFENNGRGSRVIV 312
Cdd:pfam13401   84 VAVVLIIDEaqhLSLEALEELRDLLNLSSKLLQLIL 119
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
576-688 5.94e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 46.85  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  576 NTTTAALSTTDLSCVRSLTVFGDGGDAVSNLRKCKLLRVLDLEQCTtalsddhlaDICKLWNLRYLSIGmSSNVTMLPDN 655
Cdd:COG4886     62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLS-GNQLTDLPEE 131

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1002309591  656 IRRLKLLETIHLSKTKVTMLPLQVVGLPCLAHL 688
Cdd:COG4886    132 LANLTNLKELDLSNNQLTDLPEPLGNLTNLKSL 164
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
604-723 1.34e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 45.69  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  604 SNLRKCKLLRVLDLeqcttalSDDHLADI----CKLWNLRYLSIGmSSNVTMLPDNIRRLKLLETIHLSKTKVTMLPLQV 679
Cdd:COG4886    153 EPLGNLTNLKSLDL-------SNNQLTDLpeelGNLTNLKELDLS-NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPL 224

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1002309591  680 VGLPclahlvgkfKLllpdqrgkKTVVISN----ELEKLAKKSNLQTL 723
Cdd:COG4886    225 ANLT---------NL--------ETLDLSNnqltDLPELGNLTNLEEL 255
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 206-291 1.85e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 42.75  E-value: 1.85e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   206 RVIAIVGFRGSGKTTLARAVYSRSGRQFRERAWVDASRWTDVGDLLADIVRQVCLGEYDVSESHEENLRNRLKNKRY-LI 284
Cdd:smart00382    3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPdVL 82


                    ....*..
gi 1002309591   285 VLDDISM 291
Cdd:smart00382   83 ILDEITS 89
COG3899 COG3899
Predicted ATPase [General function prediction only];
28-232 6.58e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.08  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591   28 LRDLSHESASMQNDLLLLAAFMDDQLRRSSSSPAAERPTAVLRAYTELMRELTHDMEDSIERFLHRVAPRDDHGGAGAPS 107
Cdd:COG3899    137 LGLLLGGLLLAALAALLALAALAAAAAAAAAAAAARAARLRRARAARLAALALRALLLLVLLLLLLLLLLGLLLAAAAAL 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  108 WPRRAARWVATLRTRLRFAAEIRKLKTRLEDETKRLRNAVEAAAAAGGGGHSSATPALAAAAPRGGHVEPNP-VGMEKPI 186
Cdd:COG3899    217 AAAAAAAAAAAPAAPVVLVAALLLALAALLALLLLAARLLGLAGAAALLLLGLLAAAAAGRRLLARRLIPQPlVGREAEL 296

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1002309591  187 EHLVQLLDEAGAGGGpqqlRVIAIVGFRGSGKTTLARAVYSRSGRQ 232
Cdd:COG3899    297 AALLAALERARAGRG----ELVLVSGEAGIGKSRLVRELARRARAR 338
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
606-688 8.88e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.00  E-value: 8.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  606 LRKCKLLRVLDLEQctTALSDdhL-ADICKLWNLRYLSIGmSSNVTMLPDNIRRLKLLETIHLSKTKVTMLPLQVVGLPC 684
Cdd:COG4886    109 LSNLTNLESLDLSG--NQLTD--LpEELANLTNLKELDLS-NNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183


                   ....
gi 1002309591  685 LAHL 688
Cdd:COG4886    184 LKEL 187
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 208-233 3.50e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 39.08  E-value: 3.50e-03
                           10        20
                   ....*....|....*....|....*.
gi 1002309591  208 IAIVGFRGSGKTTLARAVYSRSGRQF 233
Cdd:cd00464      2 IVLIGMMGAGKTTVGRLLAKALGLPF 27
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 178-232 6.01e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 38.64  E-value: 6.01e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1002309591  178 NPVGMEKPIEHLVQLLDEAGAGGGPqqlrVIAIVGFRGSGKTTLARAVYSRSGRQ 232
Cdd:pfam13191    1 RLVGREEELEQLLDALDRVRSGRPP----SVLLTGEAGTGKTTLLRELLRALERD 51
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
186-289 8.63e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 39.83  E-value: 8.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002309591  186 IEHLVQLLDEAGAGGGPqqlRVIAIVGFRGSGKTTLARAVYSRSGRQFRER------AWVDASRWTDVGDLLADIVRQVC 259
Cdd:COG1474     35 IEELASALRPALRGERP---SNVLIYGPTGTGKTAVAKYVLEELEEEAEERgvdvrvVYVNCRQASTRYRVLSRILEELG 111

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1002309591  260 LGeYDVSE---SHEEnLRNRLKN------KRYLIVLDDI 289
Cdd:COG1474    112 SG-EDIPStglSTDE-LFDRLYEalderdGVLVVVLDEI 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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