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Conserved domains on  [gi|1002313747|ref|XP_015620244|]
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wall-associated receptor kinase 3 isoform X2 [Oryza sativa Japonica Group]

Protein Classification

GUB_WAK_bind and EGF_CA domain-containing protein( domain architecture ID 10622381)

GUB_WAK_bind and EGF_CA domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GUB_WAK_bind pfam13947
Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain ...
42-103 2.03e-09

Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain is the extracellular part of this serine/threonine kinase that binds to the cell-wall pectins.


:

Pssm-ID: 464052  Cd Length: 64  Bit Score: 53.44  E-value: 2.03e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002313747  42 DTCGDVGVPYLFGIDGG--SCSFlPGFNLTCDRTKQPhRLFLGDGSHLQVTEISLANYTVRVLN 103
Cdd:pfam13947   3 PSCGNVNISYPFWLGNRppYCGY-PGFELSCNDNNTP-ILTIPSSGNYRVLNINYENQTIRVAD 64
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
325-353 1.50e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


:

Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.85  E-value: 1.50e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1002313747 325 DIDECSLPGKCF--GECTNTPGNYSCRCPRG 353
Cdd:cd00054     1 DIDECASGNPCQngGTCVNTVGSYRCSCPPG 31
 
Name Accession Description Interval E-value
GUB_WAK_bind pfam13947
Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain ...
42-103 2.03e-09

Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain is the extracellular part of this serine/threonine kinase that binds to the cell-wall pectins.


Pssm-ID: 464052  Cd Length: 64  Bit Score: 53.44  E-value: 2.03e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002313747  42 DTCGDVGVPYLFGIDGG--SCSFlPGFNLTCDRTKQPhRLFLGDGSHLQVTEISLANYTVRVLN 103
Cdd:pfam13947   3 PSCGNVNISYPFWLGNRppYCGY-PGFELSCNDNNTP-ILTIPSSGNYRVLNINYENQTIRVAD 64
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
325-353 1.50e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.85  E-value: 1.50e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1002313747 325 DIDECSLPGKCF--GECTNTPGNYSCRCPRG 353
Cdd:cd00054     1 DIDECASGNPCQngGTCVNTVGSYRCSCPPG 31
EGF_CA smart00179
Calcium-binding EGF-like domain;
325-353 1.59e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.85  E-value: 1.59e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1002313747  325 DIDECSLPGKCF--GECTNTPGNYSCRCPRG 353
Cdd:smart00179   1 DIDECASGNPCQngGTCVNTVGSYRCECPPG 31
EGF_CA pfam07645
Calcium-binding EGF domain;
325-353 1.48e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 36.06  E-value: 1.48e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1002313747 325 DIDECSLPGK-C--FGECTNTPGNYSCRCPRG 353
Cdd:pfam07645   1 DVDECATGTHnCpaNTVCVNTIGSFECRCPDG 32
 
Name Accession Description Interval E-value
GUB_WAK_bind pfam13947
Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain ...
42-103 2.03e-09

Wall-associated receptor kinase galacturonan-binding; This cysteine-rich GUB_WAK_bind domain is the extracellular part of this serine/threonine kinase that binds to the cell-wall pectins.


Pssm-ID: 464052  Cd Length: 64  Bit Score: 53.44  E-value: 2.03e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002313747  42 DTCGDVGVPYLFGIDGG--SCSFlPGFNLTCDRTKQPhRLFLGDGSHLQVTEISLANYTVRVLN 103
Cdd:pfam13947   3 PSCGNVNISYPFWLGNRppYCGY-PGFELSCNDNNTP-ILTIPSSGNYRVLNINYENQTIRVAD 64
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
325-353 1.50e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.85  E-value: 1.50e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1002313747 325 DIDECSLPGKCF--GECTNTPGNYSCRCPRG 353
Cdd:cd00054     1 DIDECASGNPCQngGTCVNTVGSYRCSCPPG 31
EGF_CA smart00179
Calcium-binding EGF-like domain;
325-353 1.59e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.85  E-value: 1.59e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1002313747  325 DIDECSLPGKCF--GECTNTPGNYSCRCPRG 353
Cdd:smart00179   1 DIDECASGNPCQngGTCVNTVGSYRCECPPG 31
EGF_CA pfam07645
Calcium-binding EGF domain;
325-353 1.48e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 36.06  E-value: 1.48e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1002313747 325 DIDECSLPGK-C--FGECTNTPGNYSCRCPRG 353
Cdd:pfam07645   1 DVDECATGTHnCpaNTVCVNTIGSFECRCPDG 32
EGF smart00181
Epidermal growth factor-like domain;
328-359 7.68e-03

Epidermal growth factor-like domain;


Pssm-ID: 214544  Cd Length: 35  Bit Score: 34.03  E-value: 7.68e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1002313747  328 ECSLPGKCF-GECTNTPGNYSCRCPRGARGNPY 359
Cdd:smart00181   1 ECASGGPCSnGTCINTPGSYTCSCPPGYTGDKR 33
EGF cd00053
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ...
328-359 9.72e-03

Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium.


Pssm-ID: 238010  Cd Length: 36  Bit Score: 33.60  E-value: 9.72e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1002313747 328 ECSLPGKC--FGECTNTPGNYSCRCPRGARGNPY 359
Cdd:cd00053     1 ECAASNPCsnGGTCVNTPGSYRCVCPPGYTGDRS 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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