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Conserved domains on  [gi|1002234304|ref|XP_015621364|]
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importin subunit alpha-1b-like isoform X3 [Oryza sativa Japonica Group]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 1000979)

armadillo/beta-catenin-like repeat-containing protein similar to Saccharomyces cerevisiae vacuolar protein 8 that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
17-525 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 559.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  17 KASMDAAEGRRRREDITVILRKADRDRALKEKRRRPTATAAAEglpqAAHSSAIEKKLESLPMMVQGLYSDDSSMQLEST 96
Cdd:COG5064    17 KGRFSADELRRRREEQQVELRKQKREELLNKRRNLADVSEEAE----SSFIPMEQQFYSELPQLTQQLFSDDIEQQLQAV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  97 TQFRKLLSVDHCPPIDEVIRSGVLPRFVEFLTREEYPQLQFEAAWALTNIASGTAANTMAVIEHGAVPIFVKLLSSPRED 176
Cdd:COG5064    93 YKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDD 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 177 VREQAVWALGNVAGDSTKCRNLVLMHGAMLPLLQQLNEHA-KLSMLRNSAWTLSNFCRGK-PQPDFKHVEPALPVLRELI 254
Cdd:COG5064   173 VREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQALPILAKLI 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 255 LSQDEEILTDSCWALSYLSDGSNDNIQAVIETGVCDWLVELLSHPSPVVLIPALRTVGNIVTGDDAQTQCIVgHPQALPC 334
Cdd:COG5064   253 YSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVII-NCGALKA 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 335 LFNLLtTTQKKSVKREACWTISNITAGTKEQIQAVIDSNIIAPLLHLLQHAEFDVKKEAVWAISNATSGGTF--NQIEYL 412
Cdd:COG5064   332 FRSLL-SSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrpDIIRYL 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 413 VSQGCIKPLCDLLVHQDSKTVLTCLEALDNILRVGEAKKNLGACNMNIFVPMVDEADGLDKIEDLQNHDNVEIYNKAVYV 492
Cdd:COG5064   411 VSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTIYDKAYSI 490

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1002234304 493 LESYWVQEDDQQPFlipsvsESESDNEMFQFGS 525
Cdd:COG5064   491 IEKFFGEEDAVDEL------APETAGNTFTFGS 517
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
17-525 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 559.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  17 KASMDAAEGRRRREDITVILRKADRDRALKEKRRRPTATAAAEglpqAAHSSAIEKKLESLPMMVQGLYSDDSSMQLEST 96
Cdd:COG5064    17 KGRFSADELRRRREEQQVELRKQKREELLNKRRNLADVSEEAE----SSFIPMEQQFYSELPQLTQQLFSDDIEQQLQAV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  97 TQFRKLLSVDHCPPIDEVIRSGVLPRFVEFLTREEYPQLQFEAAWALTNIASGTAANTMAVIEHGAVPIFVKLLSSPRED 176
Cdd:COG5064    93 YKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDD 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 177 VREQAVWALGNVAGDSTKCRNLVLMHGAMLPLLQQLNEHA-KLSMLRNSAWTLSNFCRGK-PQPDFKHVEPALPVLRELI 254
Cdd:COG5064   173 VREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQALPILAKLI 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 255 LSQDEEILTDSCWALSYLSDGSNDNIQAVIETGVCDWLVELLSHPSPVVLIPALRTVGNIVTGDDAQTQCIVgHPQALPC 334
Cdd:COG5064   253 YSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVII-NCGALKA 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 335 LFNLLtTTQKKSVKREACWTISNITAGTKEQIQAVIDSNIIAPLLHLLQHAEFDVKKEAVWAISNATSGGTF--NQIEYL 412
Cdd:COG5064   332 FRSLL-SSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrpDIIRYL 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 413 VSQGCIKPLCDLLVHQDSKTVLTCLEALDNILRVGEAKKNLGACNMNIFVPMVDEADGLDKIEDLQNHDNVEIYNKAVYV 492
Cdd:COG5064   411 VSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTIYDKAYSI 490

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1002234304 493 LESYWVQEDDQQPFlipsvsESESDNEMFQFGS 525
Cdd:COG5064   491 IEKFFGEEDAVDEL------APETAGNTFTFGS 517
IBB pfam01749
Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), ...
 12-97 1.56e-25

Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), importin beta (karyopherin beta) binding domain. The domain mediates formation of the importin alpha beta complex; required for classical NLS import of proteins into the nucleus, through the nuclear pore complex and across the nuclear envelope. Also in the alignment is the NLS of importin alpha which overlaps with the IBB domain.


Pssm-ID: 460311 [Multi-domain]  Cd Length: 79  Bit Score: 99.92  E-value: 1.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  12 RQKGYK-ASMDAAEGRRRREDITVILRKADRDRALKeKRRRptataaaEGLPQAAHSSAIEKKLESLPMMVQGLYSDDSS 90
Cdd:pfam01749   1 RRKSFKnKGKDADELRRRREEVQVELRKQKREEQLL-KRRN-------VGAPSSSSSSAESQLLESLPEMVQGVNSDDPE 72


                  ....*..
gi 1002234304  91 MQLESTT 97
Cdd:pfam01749  73 LQLEATQ 79
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 153-189 2.10e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 52.82  E-value: 2.10e-09
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1002234304  153 NTMAVIEHGAVPIFVKLLSSPREDVREQAVWALGNVA 189
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
17-525 0e+00

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 559.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  17 KASMDAAEGRRRREDITVILRKADRDRALKEKRRRPTATAAAEglpqAAHSSAIEKKLESLPMMVQGLYSDDSSMQLEST 96
Cdd:COG5064    17 KGRFSADELRRRREEQQVELRKQKREELLNKRRNLADVSEEAE----SSFIPMEQQFYSELPQLTQQLFSDDIEQQLQAV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  97 TQFRKLLSVDHCPPIDEVIRSGVLPRFVEFLTREEYPQLQFEAAWALTNIASGTAANTMAVIEHGAVPIFVKLLSSPRED 176
Cdd:COG5064    93 YKFRKLLSKETSPPIQPVIDAGVVPRFVEFMDEIQRDMLQFEAAWALTNIASGTTQQTKVVVDAGAVPLFIQLLSSTEDD 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 177 VREQAVWALGNVAGDSTKCRNLVLMHGAMLPLLQQLNEHA-KLSMLRNSAWTLSNFCRGK-PQPDFKHVEPALPVLRELI 254
Cdd:COG5064   173 VREQAVWALGNIAGDSEGCRDYVLQCGALEPLLGLLLSSAiHISMLRNATWTLSNLCRGKnPPPDWSNISQALPILAKLI 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 255 LSQDEEILTDSCWALSYLSDGSNDNIQAVIETGVCDWLVELLSHPSPVVLIPALRTVGNIVTGDDAQTQCIVgHPQALPC 334
Cdd:COG5064   253 YSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALRSVGNIVTGSDDQTQVII-NCGALKA 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 335 LFNLLtTTQKKSVKREACWTISNITAGTKEQIQAVIDSNIIAPLLHLLQHAEFDVKKEAVWAISNATSGGTF--NQIEYL 412
Cdd:COG5064   332 FRSLL-SSPKENIRKEACWTISNITAGNTEQIQAVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGGLNrpDIIRYL 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 413 VSQGCIKPLCDLLVHQDSKTVLTCLEALDNILRVGEAKKNLGACNMNIFVPMVDEADGLDKIEDLQNHDNVEIYNKAVYV 492
Cdd:COG5064   411 VSQGFIKPLCDLLDVVDNKIIEVALDAIENILKVGEQDRLRYGKNINIYAVYVEKAGGMDAIHGLQDSVNRTIYDKAYSI 490

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1002234304 493 LESYWVQEDDQQPFlipsvsESESDNEMFQFGS 525
Cdd:COG5064   491 IEKFFGEEDAVDEL------APETAGNTFTFGS 517
IBB pfam01749
Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), ...
 12-97 1.56e-25

Importin beta binding domain; This family consists of the importin alpha (karyopherin alpha), importin beta (karyopherin beta) binding domain. The domain mediates formation of the importin alpha beta complex; required for classical NLS import of proteins into the nucleus, through the nuclear pore complex and across the nuclear envelope. Also in the alignment is the NLS of importin alpha which overlaps with the IBB domain.


Pssm-ID: 460311 [Multi-domain]  Cd Length: 79  Bit Score: 99.92  E-value: 1.56e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304  12 RQKGYK-ASMDAAEGRRRREDITVILRKADRDRALKeKRRRptataaaEGLPQAAHSSAIEKKLESLPMMVQGLYSDDSS 90
Cdd:pfam01749   1 RRKSFKnKGKDADELRRRREEVQVELRKQKREEQLL-KRRN-------VGAPSSSSSSAESQLLESLPEMVQGVNSDDPE 72


                  ....*..
gi 1002234304  91 MQLESTT 97
Cdd:pfam01749  73 LQLEATQ 79
Arm_3 pfam16186
Atypical Arm repeat; This atypical Arm repeat appears at the very C-terminus of eukaryotic ...
 464-502 8.92e-15

Atypical Arm repeat; This atypical Arm repeat appears at the very C-terminus of eukaryotic proteins such as importin subunit alpha-2, as the last of the repeating units.


Pssm-ID: 465050 [Multi-domain]  Cd Length: 49  Bit Score: 68.39  E-value: 8.92e-15
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1002234304 464 MVDEADGLDKIEDLQNHDNVEIYNKAVYVLESYWVQEDD 502
Cdd:pfam16186   2 LIEEAGGLDKIEALQNHENEEIYKKAYKIIEKYFSDEEE 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 150-189 9.03e-11

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 56.69  E-value: 9.03e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1002234304 150 TAANTMAVIEHGAVPIFVKLLSSPREDVREQAVWALGNVA 189
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 362-402 2.35e-10

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 55.54  E-value: 2.35e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1002234304 362 TKEQIQAVIDSNIIAPLLHLLQHAEFDVKKEAVWAISNATS 402
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 153-189 2.10e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 52.82  E-value: 2.10e-09
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1002234304  153 NTMAVIEHGAVPIFVKLLSSPREDVREQAVWALGNVA 189
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 133-188 2.80e-09

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 53.14  E-value: 2.80e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002234304 133 PQLQFEAAWALTNIASGtAANTMAVIEHGAVPIFVKLLSSPREDVREQAVWALGNV 188
Cdd:pfam13513   1 WRVREAAALALGSLAEG-GPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 364-402 1.31e-08

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 50.51  E-value: 1.31e-08
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1002234304  364 EQIQAVIDSNIIAPLLHLLQHAEFDVKKEAVWAISNATS 402
Cdd:smart00185   3 ENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 109-148 2.00e-07

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 47.45  E-value: 2.00e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1002234304 109 PPIDEVIRSGVLPRFVEFLtREEYPQLQFEAAWALTNIAS 148
Cdd:pfam00514   3 ENKQAVIEAGAVPPLVRLL-SSPDEEVQEEAAWALSNLAA 41
HEAT COG1413
HEAT repeat [General function prediction only];
151-314 1.85e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 47.32  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 151 AANTMAVIEH-GAVPIFVKLLSSPREDVREQAVWALGNVAGDStkcrnlvlmhgAMLPLLQQLNEHAklSMLRNSA-WTL 228
Cdd:COG1413     5 AARALGRLGDpAAVPALIAALADEDPDVRAAAARALGRLGDPR-----------AVPALLEALKDPD--PEVRAAAaEAL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 229 SNFcrGKPQpdfkhvepALPVLRELILSQDEEILTDSCWALSYLSDgsndniQAVIETgvcdwLVELLSHPSPVVLIPAL 308
Cdd:COG1413    72 GRI--GDPE--------AVPALIAALKDEDPEVRRAAAEALGRLGD------PAAVPA-----LLEALKDPDWEVRRAAA 130


                  ....*.
gi 1002234304 309 RTVGNI 314
Cdd:COG1413   131 RALGRL 136
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 109-148 3.29e-06

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 43.96  E-value: 3.29e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1002234304  109 PPIDEVIRSGVLPRFVEFLTREEyPQLQFEAAWALTNIAS 148
Cdd:smart00185   3 ENKQAVVDAGGLPALVELLKSED-EEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 276-316 1.72e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 41.67  E-value: 1.72e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1002234304 276 SNDNIQAVIETGVCDWLVELLSHPSPVVLIPALRTVGNIVT 316
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
HEAT COG1413
HEAT repeat [General function prediction only];
290-443 3.10e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.85  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 290 DWLVELLSHPSPVVLIPALRTVGNIvtgddaqtqcivGHPQALPCLFNLLTTTQKkSVKREACWTISNITagtkeqiqav 369
Cdd:COG1413    19 PALIAALADEDPDVRAAAARALGRL------------GDPRAVPALLEALKDPDP-EVRAAAAEALGRIG---------- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002234304 370 iDSNIIAPLLHLLQHAEFDVKKEAVWAISNatsggtfnqieyLVSQGCIKPLCDLLVHQDSKTVLTCLEALDNI 443
Cdd:COG1413    76 -DPEAVPALIAALKDEDPEVRRAAAEALGR------------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 246-274 3.55e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 40.90  E-value: 3.55e-05
                          10        20
                  ....*....|....*....|....*....
gi 1002234304 246 ALPVLRELILSQDEEILTDSCWALSYLSD 274
Cdd:pfam00514  13 AVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 120-225 3.58e-05

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 42.32  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 120 LPRFVEFLTREEYPQLQFEAAWALTNIASGTAantmaviehgaVPIFVKLLSSPREDVREQAVWALGNVaGDStkcrnlv 199
Cdd:pfam13646   1 LPALLQALLRDPDPEVRAAAIRALGRIGDPEA-----------VPALLELLKDEDPAVRRAAAEALGKI-GDP------- 61

                          90       100
                  ....*....|....*....|....*.
gi 1002234304 200 lmhgAMLPLLQQLNEHAKLSMLRNSA 225
Cdd:pfam13646  62 ----EALPALLELLRDDDDDVVRAAA 83
HEAT COG1413
HEAT repeat [General function prediction only];
177-358 4.13e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.46  E-value: 4.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 177 VREQAVWALGNVAGDSTkcrnlvlmhgamLPLLQQLNEHAKLSMLRNSAWTLSNFCRgkpqpdfkhvEPALPVLRELILS 256
Cdd:COG1413     1 VRRAAARALGRLGDPAA------------VPALIAALADEDPDVRAAAARALGRLGD----------PRAVPALLEALKD 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002234304 257 QDEEILTDSCWALSYLSDgsndniQAVIETgvcdwLVELLSHPSPVVLIPALRTVGNIvtgddaqtqcivGHPQALPCLF 336
Cdd:COG1413    59 PDPEVRAAAAEALGRIGD------PEAVPA-----LIAALKDEDPEVRRAAAEALGRL------------GDPAAVPALL 115

                         170       180
                  ....*....|....*....|..
gi 1002234304 337 NLLtTTQKKSVKREACWTISNI 358
Cdd:COG1413   116 EAL-KDPDWEVRRAAARALGRL 136
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 276-315 5.79e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 40.49  E-value: 5.79e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1002234304  276 SNDNIQAVIETGVCDWLVELLSHPSPVVLIPALRTVGNIV 315
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 408-445 1.42e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.36  E-value: 1.42e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1002234304 408 QIEYLVSQGCIKPLCDLLVHQDSKTVLTCLEALDNILR 445
Cdd:pfam00514   4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 318-360 1.49e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.36  E-value: 1.49e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1002234304 318 DDAQTQCIVgHPQALPCLFNLLTTtQKKSVKREACWTISNITA 360
Cdd:pfam00514   1 SPENKQAVI-EAGAVPPLVRLLSS-PDEEVQEEAAWALSNLAA 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 408-443 1.83e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 38.95  E-value: 1.83e-04
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1002234304  408 QIEYLVSQGCIKPLCDLLVHQDSKTVLTCLEALDNI 443
Cdd:smart00185   4 NKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNL 39
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 177-231 8.66e-04

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 37.35  E-value: 8.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1002234304 177 VREQAVWALGNVAGDSTkcRNLVLMHGAMLPLLQQLNEHAKLSMLRNSAWTLSNF 231
Cdd:pfam13513   3 VREAAALALGSLAEGGP--DLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 346-399 9.75e-04

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 37.35  E-value: 9.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002234304 346 SVKREACWTISNITAGTKEQIQAVIDsNIIAPLLHLLQHAEFDVKKEAVWAISN 399
Cdd:pfam13513   2 RVREAAALALGSLAEGGPDLLAPAVP-ELLPALLPLLNDDSDLVREAAAWALGR 54
HEAT COG1413
HEAT repeat [General function prediction only];
119-189 1.87e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 1.87e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002234304 119 VLPRFVEFLtREEYPQLQFEAAWALTNIASGTAantmaviehgaVPIFVKLLSSPREDVREQAVWALGNVA 189
Cdd:COG1413    79 AVPALIAAL-KDEDPEVRRAAAEALGRLGDPAA-----------VPALLEALKDPDWEVRRAAARALGRLG 137
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 307-358 2.97e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 36.19  E-value: 2.97e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1002234304 307 ALRTVGNIVTGDDAQTQCIVghPQALPCLFNLLTTTqKKSVKREACWTISNI 358
Cdd:pfam13513   7 AALALGSLAEGGPDLLAPAV--PELLPALLPLLNDD-SDLVREAAAWALGRL 55
HEAT pfam02985
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see ...
 163-189 9.98e-03

HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514).


Pssm-ID: 460773  Cd Length: 31  Bit Score: 33.66  E-value: 9.98e-03
                          10        20
                  ....*....|....*....|....*..
gi 1002234304 163 VPIFVKLLSSPREDVREQAVWALGNVA 189
Cdd:pfam02985   2 LPLLLKLLNDPSPEVREAAAEALGELA 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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