F-box/LRR-repeat protein At1g67190 [Oryza sativa Japonica Group]
F-box protein( domain architecture ID 1903342)
F-box protein functions as the substrate-recognition component of an SCF (Skp1-Cullin-F-box protein) ubiquitin-protein ligase that is involved in ubiquitin-dependent degradation
List of domain hits
Name | Accession | Description | Interval | E-value | ||
F-box_SF super family | cl45894 | F-box domain superfamily; This short domain is commonly found at the N-terminus of various ... |
2-35 | 3.41e-06 | ||
F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures. The actual alignment was detected with superfamily member cd22121: Pssm-ID: 459239 Cd Length: 35 Bit Score: 43.50 E-value: 3.41e-06
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LRR super family | cl34836 | Leucine-rich repeat (LRR) protein [Transcription]; |
124-203 | 3.75e-03 | ||
Leucine-rich repeat (LRR) protein [Transcription]; The actual alignment was detected with superfamily member COG4886: Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 39.15 E-value: 3.75e-03
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Name | Accession | Description | Interval | E-value | ||
F-box_FBXL8 | cd22121 | F-box domain found in F-box/LRR-repeat protein 8 (FBXL8) and similar proteins; FBXL8, also ... |
2-35 | 3.41e-06 | ||
F-box domain found in F-box/LRR-repeat protein 8 (FBXL8) and similar proteins; FBXL8, also called F-box and leucine-rich repeat protein 8, or F-box protein FBL8, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438893 Cd Length: 35 Bit Score: 43.50 E-value: 3.41e-06
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FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
4-39 | 5.08e-05 | ||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 40.11 E-value: 5.08e-05
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F-box-like | pfam12937 | F-box-like; This is an F-box-like family. |
1-40 | 1.18e-04 | ||
F-box-like; This is an F-box-like family. Pssm-ID: 463757 [Multi-domain] Cd Length: 45 Bit Score: 39.39 E-value: 1.18e-04
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
124-203 | 3.75e-03 | ||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 39.15 E-value: 3.75e-03
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Name | Accession | Description | Interval | E-value | ||
F-box_FBXL8 | cd22121 | F-box domain found in F-box/LRR-repeat protein 8 (FBXL8) and similar proteins; FBXL8, also ... |
2-35 | 3.41e-06 | ||
F-box domain found in F-box/LRR-repeat protein 8 (FBXL8) and similar proteins; FBXL8, also called F-box and leucine-rich repeat protein 8, or F-box protein FBL8, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438893 Cd Length: 35 Bit Score: 43.50 E-value: 3.41e-06
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FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
4-39 | 5.08e-05 | ||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 40.11 E-value: 5.08e-05
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F-box-like | pfam12937 | F-box-like; This is an F-box-like family. |
1-40 | 1.18e-04 | ||
F-box-like; This is an F-box-like family. Pssm-ID: 463757 [Multi-domain] Cd Length: 45 Bit Score: 39.39 E-value: 1.18e-04
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F-box_SF | cd09917 | F-box domain superfamily; This short domain is commonly found at the N-terminus of various ... |
2-37 | 2.22e-04 | ||
F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures. Pssm-ID: 438852 Cd Length: 35 Bit Score: 38.19 E-value: 2.22e-04
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F-box_AtSKP2-like | cd22161 | F-box domain found in Arabidopsis thaliana SKP2-like proteins (AtSKP2A and AtSKP2B) and ... |
2-45 | 2.39e-04 | ||
F-box domain found in Arabidopsis thaliana SKP2-like proteins (AtSKP2A and AtSKP2B) and similar proteins; AtSKP2A, also called FBL5-like protein (AtFBL5), is an F-box protein that regulates cell division and is degraded via the ubiquitin pathway. It acts as an auxin receptor. AtSKP2B, also called F-box/LRR-repeat protein 5 (AtFB5), is an F-box protein that does not interact with auxin. Both AtSKP2A and AtSKP2B are components of SCF(SKP2A/SKP2B) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (including cell cycle repressors). AtSKP2A regulates the stability of the transcription factors E2FC and DPB, repressors of cell proliferation. It confers increased tolerance to osmotic stress by promoting cell division, especially in meristems and promotes the formation of lateral root primordia. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438932 Cd Length: 48 Bit Score: 38.57 E-value: 2.39e-04
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F-box_FBXO33 | cd22104 | F-box domain found in F-box only protein 33 (FBXO33) and similar proteins; FBXO33, also called ... |
4-35 | 5.75e-04 | ||
F-box domain found in F-box only protein 33 (FBXO33) and similar proteins; FBXO33, also called FBX33, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It exerts similar functions as F-box involved in polyQ pathogenesis (FipoQ) in modulating the ubiquitination and solubility of expanded SCA3-polyQ proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438876 Cd Length: 48 Bit Score: 37.62 E-value: 5.75e-04
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F-box | pfam00646 | F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ... |
1-39 | 1.06e-03 | ||
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 425796 Cd Length: 43 Bit Score: 36.75 E-value: 1.06e-03
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
124-203 | 3.75e-03 | ||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 39.15 E-value: 3.75e-03
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
125-180 | 4.55e-03 | ||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 39.15 E-value: 4.55e-03
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Blast search parameters | ||||
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