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Conserved domains on  [gi|1002235569|ref|XP_015621983|]
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F-box protein SKIP24 isoform X2 [Oryza sativa Japonica Group]

Protein Classification

F-box protein( domain architecture ID 10584247)

F-box protein is the substrate-recognition component of a SCF(Skp1-cullin-F-box) E3 ubiquitin ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins

CATH:  1.20.1280.50
Gene Ontology:  GO:0019005|GO:0005515
PubMed:  10581972|31898225|11178263
SCOP:  4001927

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
F-box-like pfam12937
F-box-like; This is an F-box-like family.
 4-53 4.72e-03

F-box-like; This is an F-box-like family.


:

Pssm-ID: 463757 [Multi-domain]  Cd Length: 45  Bit Score: 33.61  E-value: 4.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002235569   4 SDLPDELWARVLELGAgagaassalgFRDLCALAIASRRLRRLSLHPSLW 53
Cdd:pfam12937   2 SSLPDEILLQIFSYLD----------PKDLLRLALVCRRWRELASDDSLW 41
 
Name Accession Description Interval E-value
F-box-like pfam12937
F-box-like; This is an F-box-like family.
 4-53 4.72e-03

F-box-like; This is an F-box-like family.


Pssm-ID: 463757 [Multi-domain]  Cd Length: 45  Bit Score: 33.61  E-value: 4.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002235569   4 SDLPDELWARVLELGAgagaassalgFRDLCALAIASRRLRRLSLHPSLW 53
Cdd:pfam12937   2 SSLPDEILLQIFSYLD----------PKDLLRLALVCRRWRELASDDSLW 41
F-box_unchar cd22139
F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 ...
 5-57 4.86e-03

F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 (FBXO3); This subfamily corresponds to a group of uncharacterized F-box proteins which show sequence similarity to F-box only protein 3 (FBXO3). FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, that mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438911  Cd Length: 45  Bit Score: 33.76  E-value: 4.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1002235569   5 DLPDELWARVLELGAGagaassalgfRDLCALAIASRRLRRLSLHPSLWSALL 57
Cdd:cd22139     3 CLPDELWLHIFSFLSP----------KDLCQVALVCRRFNRLASDESLWKQIC 45
 
Name Accession Description Interval E-value
F-box-like pfam12937
F-box-like; This is an F-box-like family.
 4-53 4.72e-03

F-box-like; This is an F-box-like family.


Pssm-ID: 463757 [Multi-domain]  Cd Length: 45  Bit Score: 33.61  E-value: 4.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002235569   4 SDLPDELWARVLELGAgagaassalgFRDLCALAIASRRLRRLSLHPSLW 53
Cdd:pfam12937   2 SSLPDEILLQIFSYLD----------PKDLLRLALVCRRWRELASDDSLW 41
F-box_unchar cd22139
F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 ...
 5-57 4.86e-03

F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 (FBXO3); This subfamily corresponds to a group of uncharacterized F-box proteins which show sequence similarity to F-box only protein 3 (FBXO3). FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, that mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438911  Cd Length: 45  Bit Score: 33.76  E-value: 4.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1002235569   5 DLPDELWARVLELGAGagaassalgfRDLCALAIASRRLRRLSLHPSLWSALL 57
Cdd:cd22139     3 CLPDELWLHIFSFLSP----------KDLCQVALVCRRFNRLASDESLWKQIC 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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