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Conserved domains on  [gi|1002238170|ref|XP_015623289|]
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serrate RNA effector molecule isoform X2 [Oryza sativa Japonica Group]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ARS2 super family cl20283
Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a ...
 443-620 2.59e-28

Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance.


The actual alignment was detected with superfamily member pfam04959:

Pssm-ID: 461498  Cd Length: 195  Bit Score: 112.29  E-value: 2.59e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 443 RADTKNANMDKSSAADWEKKLDYFWQERLtNGKDPLV---ALTAKDKIDASAdkvLESYVTKVKDDNYGWTYGCGAKGci 519
Cdd:pfam04959   1 RGPGPSGRITSAEVVEWQKGFEERLEPLL-SEKETLSeeeAMKMGKKDPEQE---VEKFVRKNTQELAKDKWLCPLSG-- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 520 KVFHAPDFVLKHLNLKHPDLVSKLTSRVQediYFQNYMNDPNAPgGTPVMqqQSPEQQGPTPSELTPG-AFGGQGSFVEM 598
Cdd:pfam04959  75 KKFKGPEFVRKHILNKHGDKVEEVRSEVE---FFNNYLADAKRP-ATPEL--KPKPPPRPANRRERPGrAFPSQRPQGQM 148

                         170       180
                  ....*....|....*....|..
gi 1002238170 599 PTPPVLIPVPGAGPLGPFVPAP 620
Cdd:pfam04959 149 SDGHPRPPMDGPGGGPPFPPNQ 170
SERRATE_Ars2_N super family cl13496
SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) ...
 206-287 1.74e-16

SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) from plants and its homolog, Ars2, from animals. They play a role in nuclear RNA metabolism. They interact with the nuclear cap-binding complex (CBC) and mediates interactions with diverse RNA processing and transport machineries in a transcript-dependent manner. Interestingly, the plant SERRATE does not have the RNA recognition motif (RRM) domain found in metazoans and S. pombe. This domain has two completely conserved Y residues that may be functionally important.


The actual alignment was detected with superfamily member pfam12066:

Pssm-ID: 463453 [Multi-domain]  Cd Length: 110  Bit Score: 75.74  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 206 KQFTQKLEDDVSPGEAESRYQEYKTSYITSQKQDYFDHHKNEDRLKDMYHPTNLLSVIERRNELCKAAAKNLILDLRSGT 285
Cdd:pfam12066   1 KQFLESQEDDIEDEEAQKKYDEYKLEFQRKQANEFFVAHKDEEWFKEKYHPEERDKRREELREFRRKRLEVFEEDLESGV 80


                  ..
gi 1002238170 286 LD 287
Cdd:pfam12066  81 FD 82
 
Name Accession Description Interval E-value
ARS2 pfam04959
Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a ...
 443-620 2.59e-28

Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance.


Pssm-ID: 461498  Cd Length: 195  Bit Score: 112.29  E-value: 2.59e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 443 RADTKNANMDKSSAADWEKKLDYFWQERLtNGKDPLV---ALTAKDKIDASAdkvLESYVTKVKDDNYGWTYGCGAKGci 519
Cdd:pfam04959   1 RGPGPSGRITSAEVVEWQKGFEERLEPLL-SEKETLSeeeAMKMGKKDPEQE---VEKFVRKNTQELAKDKWLCPLSG-- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 520 KVFHAPDFVLKHLNLKHPDLVSKLTSRVQediYFQNYMNDPNAPgGTPVMqqQSPEQQGPTPSELTPG-AFGGQGSFVEM 598
Cdd:pfam04959  75 KKFKGPEFVRKHILNKHGDKVEEVRSEVE---FFNNYLADAKRP-ATPEL--KPKPPPRPANRRERPGrAFPSQRPQGQM 148

                         170       180
                  ....*....|....*....|..
gi 1002238170 599 PTPPVLIPVPGAGPLGPFVPAP 620
Cdd:pfam04959 149 SDGHPRPPMDGPGGGPPFPPNQ 170
SERRATE_Ars2_N pfam12066
SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) ...
 206-287 1.74e-16

SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) from plants and its homolog, Ars2, from animals. They play a role in nuclear RNA metabolism. They interact with the nuclear cap-binding complex (CBC) and mediates interactions with diverse RNA processing and transport machineries in a transcript-dependent manner. Interestingly, the plant SERRATE does not have the RNA recognition motif (RRM) domain found in metazoans and S. pombe. This domain has two completely conserved Y residues that may be functionally important.


Pssm-ID: 463453 [Multi-domain]  Cd Length: 110  Bit Score: 75.74  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 206 KQFTQKLEDDVSPGEAESRYQEYKTSYITSQKQDYFDHHKNEDRLKDMYHPTNLLSVIERRNELCKAAAKNLILDLRSGT 285
Cdd:pfam12066   1 KQFLESQEDDIEDEEAQKKYDEYKLEFQRKQANEFFVAHKDEEWFKEKYHPEERDKRREELREFRRKRLEVFEEDLESGV 80


                  ..
gi 1002238170 286 LD 287
Cdd:pfam12066  81 FD 82
 
Name Accession Description Interval E-value
ARS2 pfam04959
Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a ...
 443-620 2.59e-28

Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance.


Pssm-ID: 461498  Cd Length: 195  Bit Score: 112.29  E-value: 2.59e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 443 RADTKNANMDKSSAADWEKKLDYFWQERLtNGKDPLV---ALTAKDKIDASAdkvLESYVTKVKDDNYGWTYGCGAKGci 519
Cdd:pfam04959   1 RGPGPSGRITSAEVVEWQKGFEERLEPLL-SEKETLSeeeAMKMGKKDPEQE---VEKFVRKNTQELAKDKWLCPLSG-- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 520 KVFHAPDFVLKHLNLKHPDLVSKLTSRVQediYFQNYMNDPNAPgGTPVMqqQSPEQQGPTPSELTPG-AFGGQGSFVEM 598
Cdd:pfam04959  75 KKFKGPEFVRKHILNKHGDKVEEVRSEVE---FFNNYLADAKRP-ATPEL--KPKPPPRPANRRERPGrAFPSQRPQGQM 148

                         170       180
                  ....*....|....*....|..
gi 1002238170 599 PTPPVLIPVPGAGPLGPFVPAP 620
Cdd:pfam04959 149 SDGHPRPPMDGPGGGPPFPPNQ 170
SERRATE_Ars2_N pfam12066
SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) ...
 206-287 1.74e-16

SERRATE/Ars2, N-terminal domain; This domain can be found in the N terminus of the SERRATE (SE) from plants and its homolog, Ars2, from animals. They play a role in nuclear RNA metabolism. They interact with the nuclear cap-binding complex (CBC) and mediates interactions with diverse RNA processing and transport machineries in a transcript-dependent manner. Interestingly, the plant SERRATE does not have the RNA recognition motif (RRM) domain found in metazoans and S. pombe. This domain has two completely conserved Y residues that may be functionally important.


Pssm-ID: 463453 [Multi-domain]  Cd Length: 110  Bit Score: 75.74  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002238170 206 KQFTQKLEDDVSPGEAESRYQEYKTSYITSQKQDYFDHHKNEDRLKDMYHPTNLLSVIERRNELCKAAAKNLILDLRSGT 285
Cdd:pfam12066   1 KQFLESQEDDIEDEEAQKKYDEYKLEFQRKQANEFFVAHKDEEWFKEKYHPEERDKRREELREFRRKRLEVFEEDLESGV 80


                  ..
gi 1002238170 286 LD 287
Cdd:pfam12066  81 FD 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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