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Conserved domains on  [gi|1002240979|ref|XP_015624780|]
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3-ketoacyl-CoA synthase 12 [Oryza sativa Japonica Group]

Protein Classification

type III polyketide synthase( domain architecture ID 10552001)

type III polyketide synthase, similar to chalcone and stilbene synthase, which are involved in the synthesis of chalcone or stilbene, respectively, by catalyzing the addition of three molecules of malonyl-CoA to a starter CoA ester

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 32-305 2.43e-145

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


:

Pssm-ID: 429970  Cd Length: 290  Bit Score: 416.65  E-value: 2.43e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  32 CYLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVLDAREDcPTLRDALDEMDDFF 111
Cdd:pfam08392   9 VYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPPD-PTLAEAREEAEEVI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 112 DDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMA 191
Cdd:pfam08392  88 FGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLLQVHPNTYA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 192 LVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRLGV 271
Cdd:pfam08392 168 LVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEEDEDGKVGV 247

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1002240979 272 SLSKALPKAAVRAFTENLQRLAPRILPAGELARF 305
Cdd:pfam08392 248 SLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRF 281
Ketoacyl-synt_C super family cl21486
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar ...
 333-406 7.61e-13

Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.


The actual alignment was detected with superfamily member pfam08541:

Pssm-ID: 451266  Cd Length: 90  Bit Score: 64.06  E-value: 7.61e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:pfam08541  11 IDWFVPHQANLRIIDAVAKRLGLP-----PEKVVvnLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFGAGL 81
 
Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 32-305 2.43e-145

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


Pssm-ID: 429970  Cd Length: 290  Bit Score: 416.65  E-value: 2.43e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  32 CYLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVLDAREDcPTLRDALDEMDDFF 111
Cdd:pfam08392   9 VYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPPD-PTLAEAREEAEEVI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 112 DDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMA 191
Cdd:pfam08392  88 FGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLLQVHPNTYA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 192 LVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRLGV 271
Cdd:pfam08392 168 LVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEEDEDGKVGV 247

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1002240979 272 SLSKALPKAAVRAFTENLQRLAPRILPAGELARF 305
Cdd:pfam08392 248 SLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRF 281
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 32-413 2.46e-107

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 322.64  E-value: 2.46e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  32 CYLLDYACHKPSDDRkvttelAGAIIERNKRL----GLPEYRFLLKvivnsgIGEHTYSPRNVLDAREDcPTLRDALDEM 107
Cdd:cd00831    19 SELVDFYRRLFSSDH------LPELKEKLKRLcaktGIETRYLVLP------GGEETYAPRPEMSPSLD-ERNDIALEEA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 108 DDFFDDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRP 187
Cdd:cd00831    86 RELAEEAARGALDEAGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALDLAKDLLEANP 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 188 RTMALVLTSESCAPnWYTGTD-KSMMLGNCLFRCGGAAALLTNDPAFRS--RAKMELRCLVRAHIgahddahaaavhrED 264
Cdd:cd00831   166 GARVLVVSTELCSL-WYRGPDhRSMLVGNALFGDGAAAVLLSNDPRDRRreRPLFELVRAASTLL-------------PD 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 265 ADGRLGVSLSKAlpkaavrAFTENLQRLAPRILpAGELARFAARLLLRKLlrrkaaagaaaKINFKTGVDHFCLHPGGTA 344
Cdd:cd00831   232 SEDAMGWHLGEE-------GLTFVLSRDVPRLV-EKNLERVLRKLLARLG-----------IGLFKLAFDHWCVHPGGRA 292

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002240979 345 VIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYW 413
Cdd:cd00831   293 VLDAVEKALGLSPEDLEASRMVLRRYGNMSSSSVLYVLAYMEAKGRVKRGDRGLLIAFGPGFTCESAVW 361
PLN02854 PLN02854
3-ketoacyl-CoA synthase
 33-433 5.38e-106

3-ketoacyl-CoA synthase


Pssm-ID: 215459  Cd Length: 521  Bit Score: 324.60  E-value: 5.38e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVL---------DAREDCPTLrdA 103
Cdd:PLN02854  115 YLVDFACYKPEDERKISVDSFLTMTEENGSFEDETVQFQRRISTRSGLGDETYLPRGITsrppnlcmeEARAEAEAV--M 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 104 LDEMDDFFDDAVAavlaraavSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVM 183
Cdd:PLN02854  193 FGALDSLFSKTGV--------KPRDIGILIVNCSLFNPTPSLSAMIVNHYKLRTDIKSYNLGGMGCSAGLISIDLANDLL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 184 LTRPRTMALVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHRE 263
Cdd:PLN02854  265 KANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAVLLSNKARDRKRSKYQLVHTVRTHKGADDKNYNCVYQRE 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 264 DADGRLGVSLSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLHPGGT 343
Cdd:PLN02854  345 DDKGTIGVSLARELMAVAGDALKTNITTLGPLVLPLSEQFMFFVTLVRRKLLKAKVKPYIP---DFKLAFEHFCIHAGGR 421

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 344 AVIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDL---- 419
Cdd:PLN02854  422 AVLDELQKNLQLSDWHMEPSRMTLHRFGNTSSSSLWYELAYTEAKGRVSAGDRVWQIAFGSGFKCNSAVWKALREIptge 501

                         410
                  ....*....|....
gi 1002240979 420 ADAGAWEDCIHDYP 433
Cdd:PLN02854  502 STGNPWADSIDRYP 515
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 125-406 8.49e-31

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 121.79  E-value: 8.49e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 125 SPRDVDLLV-INV-GSFSPSPSLadRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPN 202
Cdd:COG3424    95 DPEDIDHLVtVSCtGFAAPGLDA--RLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRADPDAVVLVVCVELCSLT 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 203 WYTGTD-KSMMLGNCLFRCGGAAALLTNDPAFRSRAKmelrcLVRAHigahddahaaAVHREDA---------DGRLGVS 272
Cdd:COG3424   173 FQRDDDsKDNLVANALFGDGAAAVVVSGDPRPGPGPR-----ILAFR----------SYLIPDTedvmgwdvgDTGFRMV 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 273 LSKALPKAAVRAFTENLQRLaprilpageLARFAARlllrkllrrkaaagaaakinfKTGVDHFCLHPGGTAVIEAVRKS 352
Cdd:COG3424   238 LSPEVPDLIAEHLAPAVEPL---------LARHGLT---------------------IEDIDHWAVHPGGPKVLDAVEEA 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002240979 353 LGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:COG3424   288 LGLPPEALAHSREVLREYGNMSSATVLFVLERLLEEGAPAPGERGLAMAFGPGF 341
ACP_syn_III_C pfam08541
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ...
 333-406 7.61e-13

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.


Pssm-ID: 430060  Cd Length: 90  Bit Score: 64.06  E-value: 7.61e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:pfam08541  11 IDWFVPHQANLRIIDAVAKRLGLP-----PEKVVvnLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFGAGL 81
PRK09352 PRK09352
beta-ketoacyl-ACP synthase 3;
333-406 8.22e-08

beta-ketoacyl-ACP synthase 3;


Pssm-ID: 236475 [Multi-domain]  Cd Length: 319  Bit Score: 53.92  E-value: 8.22e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:PRK09352  239 IDWLVPHQANLRIIDATAKKLGLP-----MEKVVvtVDKYGNTSAASIPLALDEAVRDGRIKRGDLVLLEGFGGGL 309
 
Name Accession Description Interval E-value
FAE1_CUT1_RppA pfam08392
FAE1/Type III polyketide synthase-like protein; The members of this family are described as ...
 32-305 2.43e-145

FAE1/Type III polyketide synthase-like protein; The members of this family are described as 3-ketoacyl-CoA synthases, type III polyketide synthases, fatty acid elongases and fatty acid condensing enzymes, and are found in both prokaryotic and eukaryotic (mainly plant) species. The region featured in this family contains the active site residues, as well as motifs involved in substrate binding.


Pssm-ID: 429970  Cd Length: 290  Bit Score: 416.65  E-value: 2.43e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  32 CYLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVLDAREDcPTLRDALDEMDDFF 111
Cdd:pfam08392   9 VYLVDYSCYKPPDDRKVSTETFMEHIQRNGHLDLESLDFQRKILERSGLGEETYLPRAVLEGPPD-PTLAEAREEAEEVI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 112 DDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMA 191
Cdd:pfam08392  88 FGAVDDLFAKTGVSPRDIDILVVNCSLFNPTPSLSAMIVNRYKLRSDIKSYNLSGMGCSAGLISIDLAKNLLQVHPNTYA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 192 LVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRLGV 271
Cdd:pfam08392 168 LVVSTENITPNWYFGNDRSMLLPNCLFRMGGAAVLLSNRPADRRRAKYELVHTVRTHKGADDRAYNCVYQEEDEDGKVGV 247

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1002240979 272 SLSKALPKAAVRAFTENLQRLAPRILPAGELARF 305
Cdd:pfam08392 248 SLSKDLMKVAGRALKTNITTLGPLVLPLSEQLRF 281
CHS_like cd00831
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ...
 32-413 2.46e-107

Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.


Pssm-ID: 238427 [Multi-domain]  Cd Length: 361  Bit Score: 322.64  E-value: 2.46e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  32 CYLLDYACHKPSDDRkvttelAGAIIERNKRL----GLPEYRFLLKvivnsgIGEHTYSPRNVLDAREDcPTLRDALDEM 107
Cdd:cd00831    19 SELVDFYRRLFSSDH------LPELKEKLKRLcaktGIETRYLVLP------GGEETYAPRPEMSPSLD-ERNDIALEEA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 108 DDFFDDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRP 187
Cdd:cd00831    86 RELAEEAARGALDEAGLRPSDIDHLVVNTSTGNPTPSLDAMLINRLGLRPDVKRYNLGGMGCSAGAIALDLAKDLLEANP 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 188 RTMALVLTSESCAPnWYTGTD-KSMMLGNCLFRCGGAAALLTNDPAFRS--RAKMELRCLVRAHIgahddahaaavhrED 264
Cdd:cd00831   166 GARVLVVSTELCSL-WYRGPDhRSMLVGNALFGDGAAAVLLSNDPRDRRreRPLFELVRAASTLL-------------PD 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 265 ADGRLGVSLSKAlpkaavrAFTENLQRLAPRILpAGELARFAARLLLRKLlrrkaaagaaaKINFKTGVDHFCLHPGGTA 344
Cdd:cd00831   232 SEDAMGWHLGEE-------GLTFVLSRDVPRLV-EKNLERVLRKLLARLG-----------IGLFKLAFDHWCVHPGGRA 292

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002240979 345 VIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYW 413
Cdd:cd00831   293 VLDAVEKALGLSPEDLEASRMVLRRYGNMSSSSVLYVLAYMEAKGRVKRGDRGLLIAFGPGFTCESAVW 361
PLN02854 PLN02854
3-ketoacyl-CoA synthase
 33-433 5.38e-106

3-ketoacyl-CoA synthase


Pssm-ID: 215459  Cd Length: 521  Bit Score: 324.60  E-value: 5.38e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVL---------DAREDCPTLrdA 103
Cdd:PLN02854  115 YLVDFACYKPEDERKISVDSFLTMTEENGSFEDETVQFQRRISTRSGLGDETYLPRGITsrppnlcmeEARAEAEAV--M 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 104 LDEMDDFFDDAVAavlaraavSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVM 183
Cdd:PLN02854  193 FGALDSLFSKTGV--------KPRDIGILIVNCSLFNPTPSLSAMIVNHYKLRTDIKSYNLGGMGCSAGLISIDLANDLL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 184 LTRPRTMALVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHRE 263
Cdd:PLN02854  265 KANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAVLLSNKARDRKRSKYQLVHTVRTHKGADDKNYNCVYQRE 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 264 DADGRLGVSLSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLHPGGT 343
Cdd:PLN02854  345 DDKGTIGVSLARELMAVAGDALKTNITTLGPLVLPLSEQFMFFVTLVRRKLLKAKVKPYIP---DFKLAFEHFCIHAGGR 421

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 344 AVIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDL---- 419
Cdd:PLN02854  422 AVLDELQKNLQLSDWHMEPSRMTLHRFGNTSSSSLWYELAYTEAKGRVSAGDRVWQIAFGSGFKCNSAVWKALREIptge 501

                         410
                  ....*....|....
gi 1002240979 420 ADAGAWEDCIHDYP 433
Cdd:PLN02854  502 STGNPWADSIDRYP 515
PLN02192 PLN02192
3-ketoacyl-CoA synthase
 33-433 1.98e-104

3-ketoacyl-CoA synthase


Pssm-ID: 215123  Cd Length: 511  Bit Score: 320.38  E-value: 1.98e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTELagaIIERNKRLGL---PEYRFLLKVIVNSGIGEHTYSPRNVLDAREDcPTLRDALDEMDD 109
Cdd:PLN02192  103 YLVDFSCYKPDDSRKCTRKI---FMDRSKLTGSfteENLEFQRKILERSGLGESTYLPEAVLNVPPN-PCMAEARKEAET 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 110 FFDDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRT 189
Cdd:PLN02192  179 VMFGAIDQLLAKTSVKPKDIGILIVNCSLFNPTPSLSAMVINHYKLRGNILSYNLGGMGCSAGLISIDLAKHLLQVHPNS 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 190 MALVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRL 269
Cdd:PLN02192  259 YALVISMENITLNWYFGNDRSMLVSNCLFRMGGAAILLSNKRSDRRRSKYQLVHTVRTHKGADDKCFACVTQEEDSAGKI 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 270 GVSLSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLHPGGTAVIEAV 349
Cdd:PLN02192  339 GVSLSKDLMAVAGDALKTNITTLGPLVLPMSEQLLFFATLVGKKLFKMKLKPYIP---DFKLAFEHFCIHAGGRAVLDEL 415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 350 RKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDLADA---GAWE 426
Cdd:PLN02192  416 EKNLQLSDWHMEPSRMTLYRFGNTSSSSLWYELAYSEAKGRIKKGDRTWQIAFGSGFKCNSAVWKALRTVNPAkekNPWM 495


                  ....*..
gi 1002240979 427 DCIHDYP 433
Cdd:PLN02192  496 DEIHEFP 502
PLN02932 PLN02932
3-ketoacyl-CoA synthase
 33-433 3.68e-100

3-ketoacyl-CoA synthase


Pssm-ID: 178520  Cd Length: 478  Bit Score: 308.11  E-value: 3.68e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTELAGAIIERNKRLGL--PEYRFLL----KVIVNSGIGEHTYSPRNV--LDAREDCPTLRDAL 104
Cdd:PLN02932   69 YLVDFSCYLPPSHLKASIQTIMGHVRRVREAGAwkQESDYLMdfceKILERSGLGQETYIPEGLqcLPLQQNLAVSRKET 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 105 DE-----MDDFFDDAVAavlaraavSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLA 179
Cdd:PLN02932  149 EEviigaVDNLFRNTGI--------SPSDIGILVVNSSTFNPTPSLSSILVNKFKLRDNIKSLNLGGMGCSAGVIAIDAA 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 180 RNVMLTRPRTMALVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAA 259
Cdd:PLN02932  221 KSLLQVHRNTYALVVSTENITQNLYLGNNKSMLVTNCLFRIGGAAILLSNRSRDRKRAKYELVHTVRVHTGADDRSYECA 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 260 VHREDADGRLGVSLSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLH 339
Cdd:PLN02932  301 TQEEDEDGIVGVSLSKNLPMVAARTLKINIATLGPLVLPLSEKFHFFVRFVKKKFFNPKLKHYIP---DFKLAFEHFCIH 377

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 340 PGGTAVIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDL 419
Cdd:PLN02932  378 AGGRALIDEMEKNLHLTPLDVEASRMTLHRFGNTSSSSIWYELAYTEAKGRMKKGDRIWQIALGSGFKCNSSVWVALRNV 457

                         410
                  ....*....|....*.
gi 1002240979 420 ADA--GAWEDCIHDYP 433
Cdd:PLN02932  458 KPSanNPWEDCLHKYP 473
PLN00415 PLN00415
3-ketoacyl-CoA synthase
 33-433 7.97e-99

3-ketoacyl-CoA synthase


Pssm-ID: 177808  Cd Length: 466  Bit Score: 304.31  E-value: 7.97e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTELAGAIIERNKRLGLPEYRFLLKVIVNSGIGEHTYSPRNVLDArEDCPTLRDALDEMDDFFD 112
Cdd:PLN00415   61 YLVDFSCHQPTDSCKISSETFFNMAKGAQLYTEETIQFMTRILNRSGLGDDTYSPRCMLTS-PPTPSMYEARHESELVIF 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 113 DAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMAL 192
Cdd:PLN00415  140 GALNSLFKKTGIEPREVGIFIVNCSLFNPNPSLSSMIVNRYKLKTDVKTYNLSGMGCSAGAISVDLATNLLKANPNTYAV 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 193 VLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRLGVS 272
Cdd:PLN00415  220 IVSTENMTLSMYRGNDRSMLVPNCLFRVGGAAVMLSNRSQDRVRSKYELTHIVRTHKGSSDKHYTCAEQKEDSKGIVGVA 299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 273 LSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLHPGGTAVIEAVRKS 352
Cdd:PLN00415  300 LSKELTVVAGDTLKTNLTALGPLVLPLSEKLRFILFLVKSKLFRLKVSPYVP---DFKLCFKHFCIHAGGRALLDAVEKG 376

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 353 LGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDLAD-----AGAWED 427
Cdd:PLN00415  377 LGLSEFDLEPSRMTLHRFGNTSSSSLWYELAYVEAKCRVKRGDRVWQLAFGSGFKCNSIVWRALRTIPAneslvGNPWGD 456


                  ....*.
gi 1002240979 428 CIHDYP 433
Cdd:PLN00415  457 SVHKYP 462
PLN02377 PLN02377
3-ketoacyl-CoA synthase
 33-433 4.74e-96

3-ketoacyl-CoA synthase


Pssm-ID: 166018  Cd Length: 502  Bit Score: 298.47  E-value: 4.74e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  33 YLLDYACHKPSDDRKVTTelaGAIIERNKRLG---LPEYRFLLKVIVNSGIGEHTYSPR--NVLDARedcPTLRDALDEM 107
Cdd:PLN02377   99 YLVDYSCYRAPDHLKAPF---ARFMEHSRLTGdfdDSSLEFQRKILERSGLGEDTYVPEamHYIPPR---PSMAAAREEA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 108 DDFFDDAVAAVLARAAVSPRDVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRP 187
Cdd:PLN02377  173 EQVMFGALDNLFANTNVNPKDIGILVVNCSLFNPTPSLSAMIVNKYKLRGNIRSFNLGGMGCSAGVIAVDLAKDMLQVHR 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 188 RTMALVLTSESCAPNWYTGTDKSMMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADG 267
Cdd:PLN02377  253 NTYAVVVSTENITQNWYFGNKKSMLIPNCLFRVGGSAVLLSNKSRDKRRSKYKLVHVVRTHRGADDKAFRCVYQEQDDAG 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 268 RLGVSLSKALPKAAVRAFTENLQRLAPRILPAGELARFAARLLLRKLLRRKAAAGAAakiNFKTGVDHFCLHPGGTAVIE 347
Cdd:PLN02377  333 KTGVSLSKDLMAIAGEALKTNITTLGPLVLPISEQLLFFATLVVKKLFNKKMKPYIP---DFKLAFDHFCIHAGGRAVID 409

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 348 AVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKCNSSYWVVTKDL--ADAGAW 425
Cdd:PLN02377  410 ELEKNLQLLPVHVEASRMTLHRFGNTSSSSIWYELAYIEAKGRMRKGNRVWQIAFGSGFKCNSAVWEALRHVkpSNNSPW 489


                  ....*...
gi 1002240979 426 EDCIHDYP 433
Cdd:PLN02377  490 EDCIDKYP 497
BH0617 COG3424
Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and ...
 125-406 8.49e-31

Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442650 [Multi-domain]  Cd Length: 351  Bit Score: 121.79  E-value: 8.49e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 125 SPRDVDLLV-INV-GSFSPSPSLadRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPN 202
Cdd:COG3424    95 DPEDIDHLVtVSCtGFAAPGLDA--RLINRLGLRPDVRRLPVGGMGCAAGAAGLRRAADFLRADPDAVVLVVCVELCSLT 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 203 WYTGTD-KSMMLGNCLFRCGGAAALLTNDPAFRSRAKmelrcLVRAHigahddahaaAVHREDA---------DGRLGVS 272
Cdd:COG3424   173 FQRDDDsKDNLVANALFGDGAAAVVVSGDPRPGPGPR-----ILAFR----------SYLIPDTedvmgwdvgDTGFRMV 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 273 LSKALPKAAVRAFTENLQRLaprilpageLARFAARlllrkllrrkaaagaaakinfKTGVDHFCLHPGGTAVIEAVRKS 352
Cdd:COG3424   238 LSPEVPDLIAEHLAPAVEPL---------LARHGLT---------------------IEDIDHWAVHPGGPKVLDAVEEA 287

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1002240979 353 LGLDSYDVEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:COG3424   288 LGLPPEALAHSREVLREYGNMSSATVLFVLERLLEEGAPAPGERGLAMAFGPGF 341
KAS_III cd00830
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ...
 125-406 1.32e-15

Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.


Pssm-ID: 238426 [Multi-domain]  Cd Length: 320  Bit Score: 77.58  E-value: 1.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 125 SPRDVDLLVinVGSFSP---SPSLADRVVRRFGLRDdVMAYNLSGmGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAP 201
Cdd:cd00830    68 DADDIDLII--VATSTPdylFPATACLVQARLGAKN-AAAFDINA-ACSGFLYGLSTAAGLIRSGGAKNVLVVGAETLSR 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 202 --NWytgTDKSMMLgncLFRCGGAAALLTNDP------AFRSRAKMELRclvrAHIGAHDDAHAAAVHREDADGRLGVSL 273
Cdd:cd00830   144 ilDW---TDRSTAV---LFGDGAGAVVLEATEedpgilDSVLGSDGSGA----DLLTIPAGGSRSPFEDAEGGDPYLVMD 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 274 SKALPKAAVRAFTENLQRLAprilpagelarfaarlllrkllrrkaaagaaAKINFKTG-VDHFCLHPGGTAVIEAVRKS 352
Cdd:cd00830   214 GREVFKFAVRLMPESIEEAL-------------------------------EKAGLTPDdIDWFVPHQANLRIIEAVAKR 262

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 353 LGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:cd00830   263 LGLP-----EEKVVvnLDRYGNTSAASIPLALDEAIEEGKLKKGDLVLLLGFGAGL 313
init_cond_enzymes cd00827
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ...
 65-406 1.29e-14

"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.


Pssm-ID: 238423 [Multi-domain]  Cd Length: 324  Bit Score: 74.39  E-value: 1.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979  65 LPEYRFLLKVIVNSGIGEHTYSprnvlDAREDCPTL-----RDALDEMDDffddavaavlaraavSPRDVDLLVinVGS- 138
Cdd:cd00827    21 LAEGLGVDPGKYTTGIGQRHMA-----GDDEDVPTMaveaaRRALERAGI---------------DPDDIGLLI--VATe 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 139 --FSPSPSLADRVVRRFGLrDDVMAYNLSGmGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPNWYTGTDKSMMLGNc 216
Cdd:cd00827    79 spIDKGKSAATYLAELLGL-TNAEAFDLKQ-ACYGGTAALQLAANLVESGPWRYALVVASDIASYLLDEGSALEPTLGD- 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 217 lfrcGGAAALLTNDPAFRSRakmELRCLVRAHIGAHDDAHAAAVHREDADGRLGVS--------LSKALPKAAVRAFTEN 288
Cdd:cd00827   156 ----GAAAMLVSRNPGILAA---GIVSTHSTSDPGYDFSPYPVMDGGYPKPCKLAYairltaepAGRAVFEAAHKLIAKV 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 289 LQRLAPRilpagelarfaarlllrkllrrkaaagaaakINFKTGVDHFCLH-PGGTAVIEAVRKSLGLDSYDVEPARM-A 366
Cdd:cd00827   229 VRKALDR-------------------------------AGLSEDIDYFVPHqPNGKKILEAVAKKLGGPPEKASQTRWiL 277

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1002240979 367 LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:cd00827   278 LRRVGNMYAASILLGLASLLESGKLKAGDRVLLFSYGSGF 317
FabH COG0332
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ...
 125-406 1.55e-14

3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440101 [Multi-domain]  Cd Length: 323  Bit Score: 74.38  E-value: 1.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 125 SPRDVDLLVinVGSFSP---SPSLADRVVRRFGLRDdVMAYNLSGmGCSAGLVSVDLARNVMLTRPRTMALVLTSE--SC 199
Cdd:COG0332    69 DPEDIDLII--VATVTPdylFPSTACLVQHKLGAKN-AAAFDINA-ACSGFVYALSVAAALIRSGQAKNVLVVGAEtlSR 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 200 APNWytgTDK--SMMLGnclfrCGGAAALLTNDP------AFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDA---DGR 268
Cdd:COG0332   145 IVDW---TDRstCVLFG-----DGAGAVVLEASEegpgilGSVLGSDGSGADLLVVPAGGSRNPPSPVDEGDHYlrmDGR 216

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 269 lgvslskALPKAAVRAFTENLQRLAPRilpAGeLArfaarlllrkllrrkaaagaaakinfKTGVDHFCLHPGGTAVIEA 348
Cdd:COG0332   217 -------EVFKFAVRNLPEVIREALEK---AG-LT--------------------------LDDIDWFIPHQANLRIIEA 259

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 349 VRKSLGLDsydvePAR--MALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:COG0332   260 VAKRLGLP-----EEKvvVNIDRYGNTSAASIPLALDEALREGRIKPGDLVLLAGFGAGL 314
ACP_syn_III_C pfam08541
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ...
 333-406 7.61e-13

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.


Pssm-ID: 430060  Cd Length: 90  Bit Score: 64.06  E-value: 7.61e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:pfam08541  11 IDWFVPHQANLRIIDAVAKRLGLP-----PEKVVvnLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLVGFGAGL 81
PLN03169 PLN03169
chalcone synthase family protein; Provisional
 151-405 6.98e-12

chalcone synthase family protein; Provisional


Pssm-ID: 215612 [Multi-domain]  Cd Length: 391  Bit Score: 66.65  E-value: 6.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 151 RRFGLRDDVMAYNLSGMGCSAGL----VSVDLARNvmltRPRTMALVLTSESC-----APNWYTGTDksmMLGNCLFRCG 221
Cdd:PLN03169  150 KQLGLSPDVQRVMLYFLGCSGGVaglrVAKDIAEN----NPGSRVLLTTSETTilgfrPPSPDRPYD---LVGAALFGDG 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 222 GAAALLTNDP-AFRSRAKMELRCLVRAHIGAHDDAHaaavhredaDGRL---GVS--LSKALPK---AAVRAFTENLQRL 292
Cdd:PLN03169  223 AAAVIIGADPiPVSESPFFELHTAIQQFLPGTEKTI---------DGRLteeGINfkLGRELPQkieDNIEGFCKKLMKK 293

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 293 APRilpagelarfaarlllrkllrrkaaagAAAKINfktgvDHF-CLHPGGTAVIEAVRKSLGLDSYDVEPARMALHRWG 371
Cdd:PLN03169  294 AGL---------------------------VEKDYN-----DLFwAVHPGGPAILNRLEKKLKLAPEKLECSRRALMDYG 341

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1002240979 372 NTSASSLWYVLSYM--EAKRRLNAGDRV-LMVTFGSG 405
Cdd:PLN03169  342 NVSSNTIVYVLEYMreELKKKGEEDEEWgLILAFGPG 378
PRK09352 PRK09352
beta-ketoacyl-ACP synthase 3;
333-406 8.22e-08

beta-ketoacyl-ACP synthase 3;


Pssm-ID: 236475 [Multi-domain]  Cd Length: 319  Bit Score: 53.92  E-value: 8.22e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:PRK09352  239 IDWLVPHQANLRIIDATAKKLGLP-----MEKVVvtVDKYGNTSAASIPLALDEAVRDGRIKRGDLVLLEGFGGGL 309
Chal_sti_synt_C pfam02797
Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is ...
 338-405 2.56e-07

Chalcone and stilbene synthases, C-terminal domain; This domain of chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in the N-terminal domain.


Pssm-ID: 397089  Cd Length: 151  Bit Score: 50.14  E-value: 2.56e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002240979 338 LHPGGTAVIEAVRKSLGLDSYDVEPARMALHRWGNTSASSLWYVLSYM---EAKRRLNAG----DRVLMVTFGSG 405
Cdd:pfam02797  65 VHPGGPAILDRVETKLGLEPEKLEASRRALMDYGNVSSATVLFILDEMrkkSLKKGLATTgeglDWGVLLAFGPG 139
PLN03171 PLN03171
chalcone synthase-like protein; Provisional
 128-406 2.83e-07

chalcone synthase-like protein; Provisional


Pssm-ID: 178715 [Multi-domain]  Cd Length: 399  Bit Score: 52.70  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 128 DVDLLVINVGSFSPSPSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSEsCAPNWYTGT 207
Cdd:PLN03171  129 DITHLVVTTNSGAHIPGVDFRLVPLLGLRPSVRRTMLHLNGCFAGAAALRLAKDLAENNRGARVLVVAAE-ITLLLFNGP 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 208 DKS---MMLGNCLFRCGGAAALLTNDPAFRSRAKMELRCLVRAHIGAHDDAHAAAVHREDADGRLGVSLSKALPKAAV-R 283
Cdd:PLN03171  208 DEGcfqTLLNQGLFGDGAAAVIVGADADAAERPLFEIVSAAQAIIPESDDAINMHFTEGGLDGNIGTRQVPGLIGDNIeR 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 284 AFTENLQRLAPRILPAGELARFaarlllrkllrrkaaagaaakinfktgvdhFCLHPGGTAVIEAVRKSLGLDSYDVEPA 363
Cdd:PLN03171  288 CLLDAFAPLLGGDGGAEWNDLF------------------------------WAVHPGSSAILDQVDAALGLEPEKLAAS 337

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002240979 364 RMALHRWGNTSASSLWYVLSymEAKRRLNAGDRV-------LMVTFGSGF 406
Cdd:PLN03171  338 RRVLSDYGNMFGATVIFALD--ELRRQMEEAAAAgawpelgVMMAFGPGL 385
PRK05963 PRK05963
beta-ketoacyl-ACP synthase III;
333-406 1.18e-05

beta-ketoacyl-ACP synthase III;


Pssm-ID: 180328 [Multi-domain]  Cd Length: 326  Bit Score: 47.02  E-value: 1.18e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMA--LHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:PRK05963  247 IDRFFPHQANARIVDKVCETIGIP-----RAKAAstLETYGNSSAATIPLSLSLANLEQPLREGERLLFAAAGAGM 317
PRK09258 PRK09258
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
 333-408 1.49e-04

3-oxoacyl-(acyl carrier protein) synthase III; Reviewed


Pssm-ID: 181732  Cd Length: 338  Bit Score: 43.72  E-value: 1.49e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDsydvePARMAL--HRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGFKC 408
Cdd:PRK09258  259 VDRVICHQVGAAHTRAILKALGID-----PEKVFTtfPTLGNMGPASLPITLAMAAEEGFLKPGDRVALLGIGSGLNC 331
PLN03170 PLN03170
chalcone synthase; Provisional
 143-406 5.20e-04

chalcone synthase; Provisional


Pssm-ID: 178714 [Multi-domain]  Cd Length: 401  Bit Score: 42.39  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 143 PSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPNWYTGTDKSM--MLGNCLFRC 220
Cdd:PLN03170  142 PGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLdsMVGQALFGD 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 221 GGAAALLTNDPafRSRAKMELRCLVRAhigahddAHAAAVHREDA-DGRL-GVSLSKALPKAAVRAFTENLQR-LAPRIL 297
Cdd:PLN03170  222 GAAAVIVGADP--DERVERPLFQLVSA-------SQTILPDSEGAiDGHLrEVGLTFHLLKDVPGLISKNIERsLEEAFK 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 298 PAGelarfaarlllrkllrrkaaagaaakINFKTGVdHFCLHPGGTAVIEAVRKSLGLDSYDVEPARMALHRWGNTSASS 377
Cdd:PLN03170  293 PLG--------------------------ITDYNSI-FWVAHPGGPAILDQVEAKVGLEKERMRATRHVLSEYGNMSSAC 345

                         250       260
                  ....*....|....*....|....*....
gi 1002240979 378 LWYVLSYMEaKRRLNAGDrvlmVTFGSGF 406
Cdd:PLN03170  346 VLFILDEMR-KRSAEDGQ----ATTGEGF 369
PLN03172 PLN03172
chalcone synthase family protein; Provisional
 143-388 7.53e-04

chalcone synthase family protein; Provisional


Pssm-ID: 178716  Cd Length: 393  Bit Score: 41.58  E-value: 7.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 143 PSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPNWYTGTDKSM--MLGNCLFRC 220
Cdd:PLN03172  138 PGADYQLTKLLGLKPSVKRFMMYQQGCFAGGTVLRLAKDLAENNAGSRVLVVCSEITAVTFRGPSDTHLdsLVGQALFGD 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 221 GGAAALLTNDPafRSRAKMELRCLVRAhigahddahaAAVHREDADGRLG-----VSLSKALPKAAVRAFTENLQR-LAP 294
Cdd:PLN03172  218 GAAAVIIGADP--DTKIERPLFEIVSA----------AQTILPDSDGAIDghlreVGLTFHLLKDVPGLISKNIEKsLVE 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 295 RILPAGelarfaarlllrkllrrkaaagaaakINFKTGVdHFCLHPGGTAVIEAVRKSLGLDSYDVEPARMALHRWGNTS 374
Cdd:PLN03172  286 AFAPIG--------------------------INDWNSI-FWIAHPGGPAILDQVEIKLDLKEEKLRATRHVLSDYGNMS 338

                         250
                  ....*....|....
gi 1002240979 375 ASSLWYVLSYMEAK 388
Cdd:PLN03172  339 SACVLFILDEMRKK 352
PRK12879 PRK12879
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
 333-406 8.29e-04

3-oxoacyl-(acyl carrier protein) synthase III; Reviewed


Pssm-ID: 237245 [Multi-domain]  Cd Length: 325  Bit Score: 41.39  E-value: 8.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDSydvEPARMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:PRK12879  245 IDWVIPHQANLRIIESLCEKLGIPM---EKTLVSVEYYGNTSAATIPLALDLALEQGKIKPGDTLLLYGFGAGL 315
PLN03173 PLN03173
chalcone synthase; Provisional
 143-388 2.04e-03

chalcone synthase; Provisional


Pssm-ID: 178717 [Multi-domain]  Cd Length: 391  Bit Score: 40.45  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 143 PSLADRVVRRFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPNWYTGTDKSM--MLGNCLFRC 220
Cdd:PLN03173  138 PGADYQLTKLLGLRSSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLdsLVGQALFGD 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 221 GGAAALLTNDPAFRSRAKM-ELRCLVRAHIgahddahaaavhrEDADGRLG-----VSLSKALPKAAVRAFTENLQR-LA 293
Cdd:PLN03173  218 GAAAIIIGSDPVLGVEKPLfELVSAAQTIL-------------PDSDGAIDghlreVGLTFHLLKDVPGLISKNVEKsLT 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 294 PRILPAGelarfaarlllrkllrrkaaagaaakinFKTGVDHFCL-HPGGTAVIEAVRKSLGLDSYDVEPARMALHRWGN 372
Cdd:PLN03173  285 EAFKPLG----------------------------ISDWNSLFWIaHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGN 336

                         250
                  ....*....|....*.
gi 1002240979 373 TSASSLWYVLSYMEAK 388
Cdd:PLN03173  337 MSSACVLFILDEMRKK 352
fabH CHL00203
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional
 333-406 2.18e-03

3-oxoacyl-acyl-carrier-protein synthase 3; Provisional


Pssm-ID: 164577 [Multi-domain]  Cd Length: 326  Bit Score: 39.93  E-value: 2.18e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002240979 333 VDHFCLHPGGTAVIEAVRKSLGLDSYDVepaRMALHRWGNTSASSLWYVLSYMEAKRRLNAGDRVLMVTFGSGF 406
Cdd:CHL00203  246 VDWFILHQANKRILEAIANRLSVPNSKM---ITNLEKYGNTSAASIPLALDEAIQNNKIQPGQIIVLSGFGAGL 316
PLN02577 PLN02577
hydroxymethylglutaryl-CoA synthase
 346-405 3.46e-03

hydroxymethylglutaryl-CoA synthase


Pssm-ID: 178189 [Multi-domain]  Cd Length: 459  Bit Score: 39.73  E-value: 3.46e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002240979 346 IEAVRKSLGLDSYD--VEPARMALHRWGNTSASSLWYVL-SYMEAKRRLNAGDRVLMVTFGSG 405
Cdd:PLN02577  298 LEKVSQQVAKPLYDakVQPTTLIPKQVGNMYTASLYAALaSLVHNKHSELAGKRILMFSYGSG 360
Chal_sti_synt_N pfam00195
Chalcone and stilbene synthases, N-terminal domain; The C-terminal domain of Chalcone synthase ...
 152-231 6.86e-03

Chalcone and stilbene synthases, N-terminal domain; The C-terminal domain of Chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in this N-terminal domain.


Pssm-ID: 395142  Cd Length: 225  Bit Score: 37.91  E-value: 6.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002240979 152 RFGLRDDVMAYNLSGMGCSAGLVSVDLARNVMLTRPRTMALVLTSESCAPNWYTGTDKSM--MLGNCLFRCGGAAALLTN 229
Cdd:pfam00195 144 LLGLRPSVKRVMLYFQGCYGGATVLRTAKDIAENNPGARVLVVCSEITVLGFRGPSKDRLdsLVGAALFGDGAAAVIIGA 223


                  ..
gi 1002240979 230 DP 231
Cdd:pfam00195 224 DP 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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