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Conserved domains on  [gi|1002226035|ref|XP_015624873|]
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trafficking protein particle complex subunit 1 isoform X1 [Oryza sativa Japonica Group]

Protein Classification

TRAPPC1_MUM2 domain-containing protein( domain architecture ID 10513701)

TRAPPC1_MUM2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sybindin pfam04099
Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the ...
 33-179 1.18e-64

Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the small protrusions on the surface of dendrites that receive the vast majority of excitatory synapses.


:

Pssm-ID: 282019  Cd Length: 134  Bit Score: 194.84  E-value: 1.18e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  33 AQVLYVFNRGGVCLLYREWHRPLRTLDPTQDQKLMFGLLFSLRSFTAKIDPttaekgnlgvplLPGQgCSFYSFKTNTYK 112
Cdd:pfam04099   1 IFSLYIFNRAGGLIYYKEWNRPKKTKLTTNEYKLLAGMLHSLHSISSKISP------------LPGS-SGIESLETDTFK 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002226035 113 LNFLESPSGIKLILITHPRTGDQRDTLKHIYN-LYVEYVVKNPLYAPGTPInRCELFNKHLDQYVKTL 179
Cdd:pfam04099  68 LHCLETLTGIKFVLVTDPGTGINRDSLLRKYYeLYSDYVLKNPFYSLGMPI-RCELFDEKLDQYVRSL 134
 
Name Accession Description Interval E-value
Sybindin pfam04099
Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the ...
 33-179 1.18e-64

Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the small protrusions on the surface of dendrites that receive the vast majority of excitatory synapses.


Pssm-ID: 282019  Cd Length: 134  Bit Score: 194.84  E-value: 1.18e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  33 AQVLYVFNRGGVCLLYREWHRPLRTLDPTQDQKLMFGLLFSLRSFTAKIDPttaekgnlgvplLPGQgCSFYSFKTNTYK 112
Cdd:pfam04099   1 IFSLYIFNRAGGLIYYKEWNRPKKTKLTTNEYKLLAGMLHSLHSISSKISP------------LPGS-SGIESLETDTFK 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002226035 113 LNFLESPSGIKLILITHPRTGDQRDTLKHIYN-LYVEYVVKNPLYAPGTPInRCELFNKHLDQYVKTL 179
Cdd:pfam04099  68 LHCLETLTGIKFVLVTDPGTGINRDSLLRKYYeLYSDYVLKNPFYSLGMPI-RCELFDEKLDQYVRSL 134
TRAPPC1_MUM2 cd14855
Trafficking protein particle complex subunit 1; Trafficking protein particle complex subunit 1 ...
 36-175 1.44e-62

Trafficking protein particle complex subunit 1; Trafficking protein particle complex subunit 1 (TRAPPC1), also known as MUM2 and BET5, has been identified as a component of the transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.


Pssm-ID: 341445  Cd Length: 132  Bit Score: 189.30  E-value: 1.44e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREWHRPLRT---LDPTQDQKLMFGLLFSLRSFTAKIDPTtaekgnlgvpllpGQGCSFYSFKTNTYK 112
Cdd:cd14855     3 FYIFDRHGNCIYYREWNRPKQSsngKSEEEEQKLMFGLLFSLKSFVRKISPT-------------DDTCGFHSYTTNKYK 69

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002226035 113 LNFLESPSGIKLILITHPRTGDQRDTLKHIY-NLYVEYVVKNPLYAPGTPINrCELFNKHLDQY 175
Cdd:cd14855    70 LHYYETPTGLKFVLLTDPNVGDLRDVLQQIYsNIYVEYVVKNPLYPPGEPIT-SELFRSKLDQY 132
TRS23 COG5122
Transport protein particle (TRAPP) complex subunit [Intracellular trafficking and secretion];
36-179 3.75e-11

Transport protein particle (TRAPP) complex subunit [Intracellular trafficking and secretion];


Pssm-ID: 227451  Cd Length: 134  Bit Score: 57.99  E-value: 3.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREwhrplRTLDPTQ-DQKLMFGLLFSLRSFTAKIDPTTAEKGNLGVPLLpgqgcsfysfKTNTYKLN 114
Cdd:COG5122     6 FFIINKSGGLIFQRE-----FGEGETElNSNEYLILASTLHGVSAILTQTIPLPGSSGRLVL----------YFRNFVMT 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002226035 115 FLESPSGIKLILITHPRTGDQRDTLKHIYNLYVEYVVKNPLYAPGTPInRCELFNKHLDQYVKTL 179
Cdd:COG5122    71 IFQTTTGTKFVFVAEKRTVNALFQLQKIYSLYSDYVTKNPFYSPEMPI-QCSLFDEHLKRMFEGH 134
 
Name Accession Description Interval E-value
Sybindin pfam04099
Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the ...
 33-179 1.18e-64

Sybindin-like family; Sybindin is a physiological syndecan-2 ligand on dendritic spines, the small protrusions on the surface of dendrites that receive the vast majority of excitatory synapses.


Pssm-ID: 282019  Cd Length: 134  Bit Score: 194.84  E-value: 1.18e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  33 AQVLYVFNRGGVCLLYREWHRPLRTLDPTQDQKLMFGLLFSLRSFTAKIDPttaekgnlgvplLPGQgCSFYSFKTNTYK 112
Cdd:pfam04099   1 IFSLYIFNRAGGLIYYKEWNRPKKTKLTTNEYKLLAGMLHSLHSISSKISP------------LPGS-SGIESLETDTFK 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002226035 113 LNFLESPSGIKLILITHPRTGDQRDTLKHIYN-LYVEYVVKNPLYAPGTPInRCELFNKHLDQYVKTL 179
Cdd:pfam04099  68 LHCLETLTGIKFVLVTDPGTGINRDSLLRKYYeLYSDYVLKNPFYSLGMPI-RCELFDEKLDQYVRSL 134
TRAPPC1_MUM2 cd14855
Trafficking protein particle complex subunit 1; Trafficking protein particle complex subunit 1 ...
 36-175 1.44e-62

Trafficking protein particle complex subunit 1; Trafficking protein particle complex subunit 1 (TRAPPC1), also known as MUM2 and BET5, has been identified as a component of the transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.


Pssm-ID: 341445  Cd Length: 132  Bit Score: 189.30  E-value: 1.44e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREWHRPLRT---LDPTQDQKLMFGLLFSLRSFTAKIDPTtaekgnlgvpllpGQGCSFYSFKTNTYK 112
Cdd:cd14855     3 FYIFDRHGNCIYYREWNRPKQSsngKSEEEEQKLMFGLLFSLKSFVRKISPT-------------DDTCGFHSYTTNKYK 69

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002226035 113 LNFLESPSGIKLILITHPRTGDQRDTLKHIY-NLYVEYVVKNPLYAPGTPINrCELFNKHLDQY 175
Cdd:cd14855    70 LHYYETPTGLKFVLLTDPNVGDLRDVLQQIYsNIYVEYVVKNPLYPPGEPIT-SELFRSKLDQY 132
TRAPPC_longin-like cd14853
Longin-like domains of Trafficking protein particle complex; Longin-like domains of a ...
 36-175 2.05e-22

Longin-like domains of Trafficking protein particle complex; Longin-like domains of a subfamily of core components of the trafficking protein particle complex (TRAPP), including TRAPPC2, TRAPPC4, TRAPPC1 and a TRAPPC2L, whose function is not known. TRAPP complexes are required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.


Pssm-ID: 341443  Cd Length: 132  Bit Score: 87.16  E-value: 2.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREWHRPLRTLDP-TQDQKLMFGLLFSLRSFTAKIDPTTAEKGnlgvpllpgqgcsFYSFKTNTYKLN 114
Cdd:cd14853     3 FVVVGHHGNPLYEREFTPPGQAEDDnEEEYKLLAGMLHSVRSINSKLSPNVEKYL-------------KLSDKTNEYKVH 69

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002226035 115 FLESPSGIKLILITHPRTGDQRDTLKHIY-NLYVEYVVKNPL--YAPGTPInRCELFNKHLDQY 175
Cdd:cd14853    70 AYVTATGLKFVMLTDVLMDRIEDVLKNFFsDLYVLYVKKNPNpfYEPNSPI-RSRLFDSKVQSL 132
TRAPPC4_synbindin cd14856
Trafficking protein particle complex subunit 4; Trafficking protein particle complex subunit 4 ...
 36-175 3.15e-21

Trafficking protein particle complex subunit 4; Trafficking protein particle complex subunit 4 (TRAPPC4), also known as synbindin or TRS23, has been identified as a component of the transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.


Pssm-ID: 341446  Cd Length: 127  Bit Score: 83.72  E-value: 3.15e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGvCLLY-REWHRPLRTLDPtqDQKLMF-GLLFSLRSFTAKIDPTTAEKGnlgvpllpgqgcsFYSFKTNTYKL 113
Cdd:cd14856     3 LYIINKAG-GLIYqKDFSDALAKLSS--NDYLRLaSTFHGLHAIAAQLSPVPGSSG-------------IELLETDTFRL 66

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002226035 114 NFLESPSGIKLILITHPRTGDQRDTLKHIYNLYVEYVVKNPLYAPGTPInRCELFNKHLDQY 175
Cdd:cd14856    67 HCFQTLTGIKFVLVADPKQPGLDALLRRVYELYADYVLKNPFYELEMPI-RCELFDENLQKL 127
TRS23 COG5122
Transport protein particle (TRAPP) complex subunit [Intracellular trafficking and secretion];
36-179 3.75e-11

Transport protein particle (TRAPP) complex subunit [Intracellular trafficking and secretion];


Pssm-ID: 227451  Cd Length: 134  Bit Score: 57.99  E-value: 3.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREwhrplRTLDPTQ-DQKLMFGLLFSLRSFTAKIDPTTAEKGNLGVPLLpgqgcsfysfKTNTYKLN 114
Cdd:COG5122     6 FFIINKSGGLIFQRE-----FGEGETElNSNEYLILASTLHGVSAILTQTIPLPGSSGRLVL----------YFRNFVMT 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002226035 115 FLESPSGIKLILITHPRTGDQRDTLKHIYNLYVEYVVKNPLYAPGTPInRCELFNKHLDQYVKTL 179
Cdd:COG5122    71 IFQTTTGTKFVFVAEKRTVNALFQLQKIYSLYSDYVTKNPFYSPEMPI-QCSLFDEHLKRMFEGH 134
longin-like cd14818
Longin-like domains; Longin-like domains are small protein domains present in a variety of ...
 36-175 3.36e-07

Longin-like domains; Longin-like domains are small protein domains present in a variety of proteins and members of protein complexes involved in or required for different steps during the transport of proteins from the ribosome to the ER to the plasma membrane, via the Golgi apparatus. Examples are mu and sigma subunits of the heterotetrameric adaptor protein (AP) complex, zeta and delta subunits of the heterotetrameric F-COPI complex, a subgroup of R-SNARE proteins, a subfamily of the transport protein particle (TRAPP), and the signal recognition particle receptor subunit alpha (SR-alpha).


Pssm-ID: 341426  Cd Length: 117  Bit Score: 46.75  E-value: 3.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002226035  36 LYVFNRGGVCLLYREWHRplrtldptqDQKLMFGLLFSLRSFTAKIDPttaekgnlgvpllpgQGCSFYSFKTNTYKLNF 115
Cdd:cd14818     3 LAVFDPQGQVLAASNWLG---------KKPSVKFSLIQIKSFFSKLIT---------------SGFDFLTLTIGSYTFHY 58

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002226035 116 LESPsGIKLILITHprTGDQRDTLKHIYN-LYVEYVVKNPLYAPGTPI-NRCELFNKHLDQY 175
Cdd:cd14818    59 YLNK-GLYFVVITD--EQELRQELFQTLNlLLKEFNSLHGSEVITKNIeDDLEEFESYLDIK 117
Sedlin_N pfam04628
Sedlin, N-terminal conserved region; Mutations in this protein are associated with the ...
 107-177 2.55e-04

Sedlin, N-terminal conserved region; Mutations in this protein are associated with the X-linked spondyloepiphyseal dysplasia tarda syndrome (OMIM:313400). This family represents an N-terminal conserved region.


Pssm-ID: 335859  Cd Length: 129  Bit Score: 39.17  E-value: 2.55e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002226035 107 KTNTYKLNFLESPSGIKLILI---THPRTGDQRDTLKHIYNLYVEYVVkNPLYAPGTPInRCELFNKHLDQYVK 177
Cdd:pfam04628  57 KFYKLSVSAYVTNSHIKFILVhesSTKSDENIKQFFQEVHELYVKTLM-NPFYKPNDPI-RSPAFDKKVRKLAK 128
TRAPPC2_sedlin cd14825
Trafficking protein particle complex subunit 2; Trafficking protein particle complex subunit 2 ...
 118-177 3.88e-04

Trafficking protein particle complex subunit 2; Trafficking protein particle complex subunit 2 (TRAPPC2), also known as Sedlin (SEDL) or TRS20, has been identified as a component of the transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic. In humans, deletions or point mutations in the SEDL gene cause the genetic disease spondyloepiphyseal dysplasia tarda (SEDT), an X-linked skeletal disorder.


Pssm-ID: 341429  Cd Length: 135  Bit Score: 38.66  E-value: 3.88e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002226035 118 SPSGIKLILITHPRTGDQ-RDTLKHIYNLYVEYVVkNPLYAPGTPInRCELFNKHLDQYVK 177
Cdd:cd14825    74 TAGNIRFLLLHDNKNDDGiKNFFQEVYELYVKILM-NPFYEPNTPI-RSPAFDRRVRALAK 132
TRAPPC2L cd14854
Trafficking protein particle complex subunit 2-like; Trafficking protein particle complex ...
 91-162 4.63e-04

Trafficking protein particle complex subunit 2-like; Trafficking protein particle complex subunit 2-like (TRAPPC2L) is related to TRAPPC2. Its function is not known, but there are indications that it is part of the TRAPP II complex, which is required for distinct tethering events at Golgi membranes. TRAPPC2 has been identified as a general component of transport protein particle (TRAPP), required for tethering endoplasmic reticulum (ER)-derived vesicles to Golgi membranes and for Golgi traffic.


Pssm-ID: 341444  Cd Length: 135  Bit Score: 38.34  E-value: 4.63e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1002226035  91 LGvPLLPGQGCSFYSFKTNTyklnflespsGIKLILITHPRTGDQRDT-----LKHIYNLYVEYVVkNPLYAPGTPI 162
Cdd:cd14854    57 LG-LLYPTEDYKVYGYVTNT----------KVKFILVLEDTNTPLRDNdvrtlFRRLHNAYVDAVS-NPFYPPGTPI 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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