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Conserved domains on  [gi|1002244322|ref|XP_015626379|]
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cullin-associated NEDD8-dissociated protein 1 [Oryza sativa Japonica Group]

Protein Classification

TIP120 domain-containing protein( domain architecture ID 11444352)

TIP120 domain-containing protein similar to Candida albicans cullin-associated NEDD8-dissociated protein 1 (CAND1), also called TBP-interacting protein 120 homolog (TIP120), a key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TIP120 pfam08623
TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and ...
 1052-1202 2.30e-66

TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and neddylation-dissociated protein 1) is a TATA binding protein interacting protein that enhances transcription.


:

Pssm-ID: 430111  Cd Length: 165  Bit Score: 220.85  E-value: 2.30e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322 1052 YDQTVVKQELIRTVDLGPFKHVVDDGLELRKAAFECVDTLLDSCLDQVNPSSFIVPfLLSGLGDHYDVKMPCHLILSKLA 1131
Cdd:pfam08623   14 YAETKVKPELIREVQMGPFKHKVDDGLELRKAAYECLYTLLDTCLDRLDISEFLDR-VIAGLSDEHDIKMLCNLMLIKLV 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002244322 1132 DKCPSAVLAVLDSLVDPIEKTINHKPKGDAVKQEVDRNEDMIRSALRAIAAL-SRISGNDYSMR-FKNLMNKI 1202
Cdd:pfam08623   93 VLAPDEVLRRLDSLVEPLRKTLSKKLKENAVKQELEKQEELIRSVLRASAALnSKIPGAEKSHPkWNEFVEWV 165
HEAT COG1413
HEAT repeat [General function prediction only];
929-1029 6.60e-04

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  929 EKILALLFNHCESEEEGVRNVVAECLGKIAliePRKLIPALKERTSSPAANTRATVAIAIkysiverpGKIDEImySEIS 1008
Cdd:COG1413     46 PRAVPALLEALKDPDPEVRAAAAEALGRIG---DPEAVPALIAALKDEDPEVRRAAAEAL--------GRLGDP--AAVP 112

                           90       100
                   ....*....|....*....|.
gi 1002244322 1009 TFLMLIKDSDRHVRRAAVLAL 1029
Cdd:COG1413    113 ALLEALKDPDWEVRRAAARAL 133
 
Name Accession Description Interval E-value
TIP120 pfam08623
TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and ...
 1052-1202 2.30e-66

TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and neddylation-dissociated protein 1) is a TATA binding protein interacting protein that enhances transcription.


Pssm-ID: 430111  Cd Length: 165  Bit Score: 220.85  E-value: 2.30e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322 1052 YDQTVVKQELIRTVDLGPFKHVVDDGLELRKAAFECVDTLLDSCLDQVNPSSFIVPfLLSGLGDHYDVKMPCHLILSKLA 1131
Cdd:pfam08623   14 YAETKVKPELIREVQMGPFKHKVDDGLELRKAAYECLYTLLDTCLDRLDISEFLDR-VIAGLSDEHDIKMLCNLMLIKLV 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002244322 1132 DKCPSAVLAVLDSLVDPIEKTINHKPKGDAVKQEVDRNEDMIRSALRAIAAL-SRISGNDYSMR-FKNLMNKI 1202
Cdd:pfam08623   93 VLAPDEVLRRLDSLVEPLRKTLSKKLKENAVKQELEKQEELIRSVLRASAALnSKIPGAEKSHPkWNEFVEWV 165
HEAT COG1413
HEAT repeat [General function prediction only];
929-1029 6.60e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  929 EKILALLFNHCESEEEGVRNVVAECLGKIAliePRKLIPALKERTSSPAANTRATVAIAIkysiverpGKIDEImySEIS 1008
Cdd:COG1413     46 PRAVPALLEALKDPDPEVRAAAAEALGRIG---DPEAVPALIAALKDEDPEVRRAAAEAL--------GRLGDP--AAVP 112

                           90       100
                   ....*....|....*....|.
gi 1002244322 1009 TFLMLIKDSDRHVRRAAVLAL 1029
Cdd:COG1413    113 ALLEALKDPDWEVRRAAARAL 133
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 928-1030 1.67e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.86  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  928 IEKILALLFNHcesEEEGVRNVVAECLGKIAliePRKLIPALKERTSSPAANTRATVAIAIkysiverpGKIDEimySEI 1007
Cdd:pfam13646    1 LPALLQALLRD---PDPEVRAAAIRALGRIG---DPEAVPALLELLKDEDPAVRRAAAEAL--------GKIGD---PEA 63

                           90       100
                   ....*....|....*....|....*
gi 1002244322 1008 STFL--MLIKDSDRHVRRAAVLALS 1030
Cdd:pfam13646   64 LPALleLLRDDDDDVVRAAAAEALA 88
 
Name Accession Description Interval E-value
TIP120 pfam08623
TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and ...
 1052-1202 2.30e-66

TATA-binding protein interacting (TIP20); TIP120 (also known as cullin-associated and neddylation-dissociated protein 1) is a TATA binding protein interacting protein that enhances transcription.


Pssm-ID: 430111  Cd Length: 165  Bit Score: 220.85  E-value: 2.30e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322 1052 YDQTVVKQELIRTVDLGPFKHVVDDGLELRKAAFECVDTLLDSCLDQVNPSSFIVPfLLSGLGDHYDVKMPCHLILSKLA 1131
Cdd:pfam08623   14 YAETKVKPELIREVQMGPFKHKVDDGLELRKAAYECLYTLLDTCLDRLDISEFLDR-VIAGLSDEHDIKMLCNLMLIKLV 92

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002244322 1132 DKCPSAVLAVLDSLVDPIEKTINHKPKGDAVKQEVDRNEDMIRSALRAIAAL-SRISGNDYSMR-FKNLMNKI 1202
Cdd:pfam08623   93 VLAPDEVLRRLDSLVEPLRKTLSKKLKENAVKQELEKQEELIRSVLRASAALnSKIPGAEKSHPkWNEFVEWV 165
HEAT COG1413
HEAT repeat [General function prediction only];
929-1029 6.60e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  929 EKILALLFNHCESEEEGVRNVVAECLGKIAliePRKLIPALKERTSSPAANTRATVAIAIkysiverpGKIDEImySEIS 1008
Cdd:COG1413     46 PRAVPALLEALKDPDPEVRAAAAEALGRIG---DPEAVPALIAALKDEDPEVRRAAAEAL--------GRLGDP--AAVP 112

                           90       100
                   ....*....|....*....|.
gi 1002244322 1009 TFLMLIKDSDRHVRRAAVLAL 1029
Cdd:COG1413    113 ALLEALKDPDWEVRRAAARAL 133
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 928-1030 1.67e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.86  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  928 IEKILALLFNHcesEEEGVRNVVAECLGKIAliePRKLIPALKERTSSPAANTRATVAIAIkysiverpGKIDEimySEI 1007
Cdd:pfam13646    1 LPALLQALLRD---PDPEVRAAAIRALGRIG---DPEAVPALLELLKDEDPAVRRAAAEAL--------GKIGD---PEA 63

                           90       100
                   ....*....|....*....|....*
gi 1002244322 1008 STFL--MLIKDSDRHVRRAAVLALS 1030
Cdd:pfam13646   64 LPALleLLRDDDDDVVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
928-1029 4.68e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.84  E-value: 4.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002244322  928 IEKILALLfnhcESEEEGVRNVVAECLGKIALIEPrklIPALKERTSSPAANTRATVAIAIKYSIVERPgkideimyseI 1007
Cdd:COG1413     18 VPALIAAL----ADEDPDVRAAAARALGRLGDPRA---VPALLEALKDPDPEVRAAAAEALGRIGDPEA----------V 80

                           90       100
                   ....*....|....*....|..
gi 1002244322 1008 STFLMLIKDSDRHVRRAAVLAL 1029
Cdd:COG1413     81 PALIAALKDEDPEVRRAAAEAL 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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