NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1002259808|ref|XP_015634229|]
View 

uncharacterized protein [Oryza sativa Japonica Group]

Protein Classification

WASH complex subunit 3( domain architecture ID 12103671)

WASH complex subunit 3 (WASHC3) acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting

Gene Symbol:  WASHC3
Gene Ontology:  GO:0006887|GO:0030041|GO:0071203
PubMed:  19922875

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CCDC53 pfam10152
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
 56-104 6.73e-17

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


:

Pssm-ID: 462967  Cd Length: 146  Bit Score: 71.94  E-value: 6.73e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1002259808  56 VNMFIANTVEFLNSFAAQCNDKLSLLHRKIVKLDSSLNLLEAKLRSIDD 104
Cdd:pfam10152   1 LNHFIVHTVQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAKLSSIPG 49
 
Name Accession Description Interval E-value
CCDC53 pfam10152
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
 56-104 6.73e-17

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


Pssm-ID: 462967  Cd Length: 146  Bit Score: 71.94  E-value: 6.73e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1002259808  56 VNMFIANTVEFLNSFAAQCNDKLSLLHRKIVKLDSSLNLLEAKLRSIDD 104
Cdd:pfam10152   1 LNHFIVHTVQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAKLSSIPG 49
 
Name Accession Description Interval E-value
CCDC53 pfam10152
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
 56-104 6.73e-17

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


Pssm-ID: 462967  Cd Length: 146  Bit Score: 71.94  E-value: 6.73e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1002259808  56 VNMFIANTVEFLNSFAAQCNDKLSLLHRKIVKLDSSLNLLEAKLRSIDD 104
Cdd:pfam10152   1 LNHFIVHTVQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAKLSSIPG 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH