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Conserved domains on  [gi|1002272054|ref|XP_015640328|]
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uracil phosphoribosyltransferase [Oryza sativa Japonica Group]

Protein Classification

type I phosphoribosyltransferase; uracil phosphoribosyltransferase( domain architecture ID 10010821)

type I phosphoribosyltransferase similar to phosphoribosyltransferases with specificities for hypoxanthine, guanine, and/or xanthine; uracil phosphoribosyltransferase catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02541 PLN02541
uracil phosphoribosyltransferase
 59-301 9.71e-151

uracil phosphoribosyltransferase


:

Pssm-ID: 215297  Cd Length: 244  Bit Score: 421.89  E-value: 9.71e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  59 VQRRPRAPLTAARAASPDAATGARSPSSGGQMLVFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDWLP 138
Cdd:PLN02541    1 VAPSRSSRLTRTVRASADAAASEPSPKAPQQMLVFVPPHPLIKHWLSVLRNEQTPPPIFRSAMAELGRLLIYEASRDWLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 139 TITGEIQTPVAVSSVEFIDPREPVMVVPILRAGLAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEGTRV 218
Cdd:PLN02541   81 TMTGEVQTPMGVADVEFIDPREPVAVVPILRAGLVLLEHASSVLPATKTYHLGFVRDEETLQPSMYLNKLPDKFPEGSRV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 219 LVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRS 298
Cdd:PLN02541  161 LVVDPMLATGGTIVAAIDELVSRGASVEQIRVVCAVAAPPALKKLSEKFPGLHVYAGIIDEEVNEKGYIVPGLGDAGDRS 240


                  ...
gi 1002272054 299 FAT 301
Cdd:PLN02541  241 FGT 243
 
Name Accession Description Interval E-value
PLN02541 PLN02541
uracil phosphoribosyltransferase
 59-301 9.71e-151

uracil phosphoribosyltransferase


Pssm-ID: 215297  Cd Length: 244  Bit Score: 421.89  E-value: 9.71e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  59 VQRRPRAPLTAARAASPDAATGARSPSSGGQMLVFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDWLP 138
Cdd:PLN02541    1 VAPSRSSRLTRTVRASADAAASEPSPKAPQQMLVFVPPHPLIKHWLSVLRNEQTPPPIFRSAMAELGRLLIYEASRDWLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 139 TITGEIQTPVAVSSVEFIDPREPVMVVPILRAGLAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEGTRV 218
Cdd:PLN02541   81 TMTGEVQTPMGVADVEFIDPREPVAVVPILRAGLVLLEHASSVLPATKTYHLGFVRDEETLQPSMYLNKLPDKFPEGSRV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 219 LVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRS 298
Cdd:PLN02541  161 LVVDPMLATGGTIVAAIDELVSRGASVEQIRVVCAVAAPPALKKLSEKFPGLHVYAGIIDEEVNEKGYIVPGLGDAGDRS 240


                  ...
gi 1002272054 299 FAT 301
Cdd:PLN02541  241 FGT 243
Upp COG0035
Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Uracil ...
 92-301 9.95e-99

Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Uracil phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 439805  Cd Length: 209  Bit Score: 288.89  E-value: 9.95e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  92 VFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDpREPVMVVPILRAG 171
Cdd:COG0035     4 VHVVDHPLIQHKLTLLRDKNTDTKEFRRLLEELGRLLAYEATRD-LPLEEVEVETPLGKTTGKVLA-GKKLVIVPILRAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 172 LAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIpEGTRVLVVDPMLATGGTIVAAIDLLVERGVtsKQIKVV 251
Cdd:COG0035    82 LGMLDGVLDLLPSARVGHIGLYRDEETLEPVEYYFKLPEDL-EGRTVIVLDPMLATGGSLVAAIDLLKKRGA--KDIKIV 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002272054 252 SAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:COG0035   159 CLIAAPEGIERVQEAHPDVDIYTAAIDEELNEKGYIVPGLGDAGDRLFGT 208
UPRTase pfam14681
Uracil phosphoribosyltransferase; This family includes the enzyme uracil ...
 96-301 9.21e-89

Uracil phosphoribosyltransferase; This family includes the enzyme uracil phosphoribosyltransferase (EC:2.4.2.9). This enzyme catalyzes the first step of UMP biosynthesis.


Pssm-ID: 434124  Cd Length: 204  Bit Score: 263.20  E-value: 9.21e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  96 PHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDPREPVMVVPILRAGLAMA 175
Cdd:pfam14681   1 DHPLLKHLLTILRDKSTSGPDFRFASDRIGRLLAYEALRD-LPTEEVTVETPLGTTYAGVLFDEKKICGVPILRAGEGME 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 176 ENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEgTRVLVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVA 255
Cdd:pfam14681  80 DGLRDLLPGARVGHIGIQRDEETLQPVEYYNKLPKDISD-RTVILLDPMLATGGSAIAAIQVLREHGVPEENIVVLSVIA 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1002272054 256 APPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:pfam14681 159 APEGLHRLAAAFPDVKIVTAAVDEELNENGYIVPGLGDAGDRLFGT 204
upp TIGR01091
uracil phosphoribosyltransferase; A fairly deep split in phylogenetic and UPGMA trees ...
 92-301 1.47e-84

uracil phosphoribosyltransferase; A fairly deep split in phylogenetic and UPGMA trees separates this mostly prokaryotic set of uracil phosphoribosyltransferases from a mostly eukaryotic set that includes uracil phosphoribosyltransferase, uridine kinases, and other, uncharacterized proteins. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides]


Pssm-ID: 273438  Cd Length: 207  Bit Score: 252.94  E-value: 1.47e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  92 VFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDPREpVMVVPILRAG 171
Cdd:TIGR01091   2 VVVVDHPLIKHKLTLLRDKNTDTKEFRELLRELGRLLAYEATRD-LELEEVEVETPLGETEGGRILGKK-IVLVPILRAG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 172 LAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEgTRVLVVDPMLATGGTIVAAIDLLVERGvtSKQIKVV 251
Cdd:TIGR01091  80 LGMVDGVLKLIPEAKVGHVGAYRNEETLKPVPYYSKLPEDIDE-RTVIVLDPMLATGGTMIAALDLLKKRG--PKKIKVL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002272054 252 SAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:TIGR01091 157 SIVAAPEGIEAVEKAHPDVDIYTAAIDEKLNDNGYIVPGLGDAGDRAFGT 206
PRTases_typeI cd06223
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ...
 157-275 3.59e-17

Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.


Pssm-ID: 206754 [Multi-domain]  Cd Length: 130  Bit Score: 76.28  E-value: 3.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 157 DPREPVMVVPILRAGLAMAENASSVLPAtKTYHLGLRRDEETLQPSIY--LNNLPDKIPEGTRVLVVDPMLATGGTIVAA 234
Cdd:cd06223    12 DLLEPDVVVGILRGGLPLAAALARALGL-PLAFIRKERKGPGRTPSEPygLELPLGGDVKGKRVLLVDDVIATGGTLLAA 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1002272054 235 IDLLVERGVTSkqIKVVSAVAAPPALQKLsNKFPGLHVYTG 275
Cdd:cd06223    91 IELLKEAGAKV--VGVAVLLDKPEGGARE-LASPGDPVYSL 128
 
Name Accession Description Interval E-value
PLN02541 PLN02541
uracil phosphoribosyltransferase
 59-301 9.71e-151

uracil phosphoribosyltransferase


Pssm-ID: 215297  Cd Length: 244  Bit Score: 421.89  E-value: 9.71e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  59 VQRRPRAPLTAARAASPDAATGARSPSSGGQMLVFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDWLP 138
Cdd:PLN02541    1 VAPSRSSRLTRTVRASADAAASEPSPKAPQQMLVFVPPHPLIKHWLSVLRNEQTPPPIFRSAMAELGRLLIYEASRDWLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 139 TITGEIQTPVAVSSVEFIDPREPVMVVPILRAGLAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEGTRV 218
Cdd:PLN02541   81 TMTGEVQTPMGVADVEFIDPREPVAVVPILRAGLVLLEHASSVLPATKTYHLGFVRDEETLQPSMYLNKLPDKFPEGSRV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 219 LVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRS 298
Cdd:PLN02541  161 LVVDPMLATGGTIVAAIDELVSRGASVEQIRVVCAVAAPPALKKLSEKFPGLHVYAGIIDEEVNEKGYIVPGLGDAGDRS 240


                  ...
gi 1002272054 299 FAT 301
Cdd:PLN02541  241 FGT 243
Upp COG0035
Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Uracil ...
 92-301 9.95e-99

Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Uracil phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine salvage


Pssm-ID: 439805  Cd Length: 209  Bit Score: 288.89  E-value: 9.95e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  92 VFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDpREPVMVVPILRAG 171
Cdd:COG0035     4 VHVVDHPLIQHKLTLLRDKNTDTKEFRRLLEELGRLLAYEATRD-LPLEEVEVETPLGKTTGKVLA-GKKLVIVPILRAG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 172 LAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIpEGTRVLVVDPMLATGGTIVAAIDLLVERGVtsKQIKVV 251
Cdd:COG0035    82 LGMLDGVLDLLPSARVGHIGLYRDEETLEPVEYYFKLPEDL-EGRTVIVLDPMLATGGSLVAAIDLLKKRGA--KDIKIV 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002272054 252 SAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:COG0035   159 CLIAAPEGIERVQEAHPDVDIYTAAIDEELNEKGYIVPGLGDAGDRLFGT 208
upp PRK00129
uracil phosphoribosyltransferase; Reviewed
 89-301 1.48e-96

uracil phosphoribosyltransferase; Reviewed


Pssm-ID: 234653  Cd Length: 209  Bit Score: 283.13  E-value: 1.48e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  89 QMLVFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDpREPVMVVPIL 168
Cdd:PRK00129    1 MMKVHVVDHPLIQHKLTLLRDKNTSTKRFRELLEELGRLLAYEATRD-LPLEEVEIETPLGKTTGKRIA-GKKLVIVPIL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 169 RAGLAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIpEGTRVLVVDPMLATGGTIVAAIDLLVERGVtsKQI 248
Cdd:PRK00129   79 RAGLGMVDGVLKLIPSARVGHIGLYRDEETLEPVEYYVKLPEDI-DERTVIVVDPMLATGGSAIAAIDLLKKRGA--KNI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1002272054 249 KVVSAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:PRK00129  156 KVLCLVAAPEGIKALEEAHPDVEIYTAAIDEKLNEHGYIVPGLGDAGDRLFGT 208
UPRTase pfam14681
Uracil phosphoribosyltransferase; This family includes the enzyme uracil ...
 96-301 9.21e-89

Uracil phosphoribosyltransferase; This family includes the enzyme uracil phosphoribosyltransferase (EC:2.4.2.9). This enzyme catalyzes the first step of UMP biosynthesis.


Pssm-ID: 434124  Cd Length: 204  Bit Score: 263.20  E-value: 9.21e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  96 PHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDPREPVMVVPILRAGLAMA 175
Cdd:pfam14681   1 DHPLLKHLLTILRDKSTSGPDFRFASDRIGRLLAYEALRD-LPTEEVTVETPLGTTYAGVLFDEKKICGVPILRAGEGME 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 176 ENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEgTRVLVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVA 255
Cdd:pfam14681  80 DGLRDLLPGARVGHIGIQRDEETLQPVEYYNKLPKDISD-RTVILLDPMLATGGSAIAAIQVLREHGVPEENIVVLSVIA 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1002272054 256 APPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:pfam14681 159 APEGLHRLAAAFPDVKIVTAAVDEELNENGYIVPGLGDAGDRLFGT 204
upp TIGR01091
uracil phosphoribosyltransferase; A fairly deep split in phylogenetic and UPGMA trees ...
 92-301 1.47e-84

uracil phosphoribosyltransferase; A fairly deep split in phylogenetic and UPGMA trees separates this mostly prokaryotic set of uracil phosphoribosyltransferases from a mostly eukaryotic set that includes uracil phosphoribosyltransferase, uridine kinases, and other, uncharacterized proteins. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides]


Pssm-ID: 273438  Cd Length: 207  Bit Score: 252.94  E-value: 1.47e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054  92 VFVPPHPLIKHWVSVLRNEQTPCAIFKSAMAELGRLLIYEASRDwLPTITGEIQTPVAVSSVEFIDPREpVMVVPILRAG 171
Cdd:TIGR01091   2 VVVVDHPLIKHKLTLLRDKNTDTKEFRELLRELGRLLAYEATRD-LELEEVEVETPLGETEGGRILGKK-IVLVPILRAG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 172 LAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDKIPEgTRVLVVDPMLATGGTIVAAIDLLVERGvtSKQIKVV 251
Cdd:TIGR01091  80 LGMVDGVLKLIPEAKVGHVGAYRNEETLKPVPYYSKLPEDIDE-RTVIVLDPMLATGGTMIAALDLLKKRG--PKKIKVL 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1002272054 252 SAVAAPPALQKLSNKFPGLHVYTGTIDSEVDERGFIVPGLGDAGDRSFAT 301
Cdd:TIGR01091 157 SIVAAPEGIEAVEKAHPDVDIYTAAIDEKLNDNGYIVPGLGDAGDRAFGT 206
PRTases_typeI cd06223
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ...
 157-275 3.59e-17

Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.


Pssm-ID: 206754 [Multi-domain]  Cd Length: 130  Bit Score: 76.28  E-value: 3.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 157 DPREPVMVVPILRAGLAMAENASSVLPAtKTYHLGLRRDEETLQPSIY--LNNLPDKIPEGTRVLVVDPMLATGGTIVAA 234
Cdd:cd06223    12 DLLEPDVVVGILRGGLPLAAALARALGL-PLAFIRKERKGPGRTPSEPygLELPLGGDVKGKRVLLVDDVIATGGTLLAA 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1002272054 235 IDLLVERGVTSkqIKVVSAVAAPPALQKLsNKFPGLHVYTG 275
Cdd:cd06223    91 IELLKEAGAKV--VGVAVLLDKPEGGARE-LASPGDPVYSL 128
Pribosyltran pfam00156
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ...
 157-257 3.73e-14

Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.


Pssm-ID: 425489 [Multi-domain]  Cd Length: 150  Bit Score: 68.55  E-value: 3.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 157 DPREPVMVVPILRAGLAMAENASSVLPATKTYHLGLRRDEETLQPSIYLNNLPDkiPEGTRVLVVDPMLATGGTIVAAID 236
Cdd:pfam00156  26 YGGKPDVVVGILRGGLPFAGILARRLDVPLAFVRKVSYNPDTSEVMKTSSALPD--LKGKTVLIVDDILDTGGTLLKVLE 103

                          90       100
                  ....*....|....*....|.
gi 1002272054 237 LLVERGVtsKQIKVVSAVAAP 257
Cdd:pfam00156 104 LLKNVGP--KEVKIAVLIDKP 122
PRK02304 PRK02304
adenine phosphoribosyltransferase; Provisional
 210-274 4.63e-07

adenine phosphoribosyltransferase; Provisional


Pssm-ID: 235028  Cd Length: 175  Bit Score: 48.92  E-value: 4.63e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1002272054 210 DKIPEGTRVLVVDPMLATGGTIVAAIDLLVERGVTskqikvVSAVAAPPALQKL--SNKFPGLHVYT 274
Cdd:PRK02304  109 DAIKPGDRVLIVDDLLATGGTLEAAIKLLERLGAE------VVGAAFVIELPDLggREKLEGYPVKS 169
PRK00934 PRK00934
ribose-phosphate pyrophosphokinase; Provisional
 157-281 2.15e-06

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 234868 [Multi-domain]  Cd Length: 285  Bit Score: 48.37  E-value: 2.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 157 DPREPVMVVPIlRAGLAMAENASSVLpATKTYHLGLRR---DEETLQPsiylnnlPDKIPEGTRVLVVDPMLATGGTIVA 233
Cdd:PRK00934  152 KLDDPLVLAPD-KGALELAKEAAEIL-GCEYDYLEKTRispTEVEIAP-------KNLDVKGKDVLIVDDIISTGGTMAT 222

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1002272054 234 AIDLLVERGVTSKQIKVVSAVAAPPALQKLSNKFPGLHVYTGTIDSEV 281
Cdd:PRK00934  223 AIKILKEQGAKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEV 270
Apt COG0503
Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [Nucleotide ...
 209-242 9.41e-06

Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [Nucleotide transport and metabolism]; Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein is part of the Pathway/BioSystem: Purine salvage


Pssm-ID: 440269  Cd Length: 171  Bit Score: 45.07  E-value: 9.41e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1002272054 209 PDKIPEGTRVLVVDPMLATGGTIVAAIDLLVERG 242
Cdd:COG0503   106 KDALKPGDRVLIVDDLLATGGTAKAAIKLVEEAG 139
PRK03092 PRK03092
ribose-phosphate diphosphokinase;
214-265 9.60e-05

ribose-phosphate diphosphokinase;


Pssm-ID: 179535 [Multi-domain]  Cd Length: 304  Bit Score: 43.40  E-value: 9.60e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1002272054 214 EGTRVLVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVAAPPALQKLSN 265
Cdd:PRK03092  200 EGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHGVLSGPAAERLKN 251
PLN02369 PLN02369
ribose-phosphate pyrophosphokinase
 214-265 1.84e-04

ribose-phosphate pyrophosphokinase


Pssm-ID: 215209 [Multi-domain]  Cd Length: 302  Bit Score: 42.37  E-value: 1.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1002272054 214 EGTRVLVVDPMLATGGTIVAAIDLLVERGVTSKQIKVVSAVAAPPALQKLSN 265
Cdd:PLN02369  201 KGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHAVFSPPAIERLSS 252
PLN02293 PLN02293
adenine phosphoribosyltransferase
 210-238 5.91e-04

adenine phosphoribosyltransferase


Pssm-ID: 177930  Cd Length: 187  Bit Score: 40.04  E-value: 5.91e-04
                          10        20
                  ....*....|....*....|....*....
gi 1002272054 210 DKIPEGTRVLVVDPMLATGGTIVAAIDLL 238
Cdd:PLN02293  120 GAVEPGERALVIDDLIATGGTLCAAINLL 148
Hpt1 COG2236
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ...
 160-254 6.95e-04

Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage


Pssm-ID: 441837 [Multi-domain]  Cd Length: 153  Bit Score: 39.44  E-value: 6.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002272054 160 EPVMVVPILRAGLAMA---------ENASSVlpATKTYhlglRRDEETLQPSIYLNNLPDKIpEGTRVLVVDPMLATGGT 230
Cdd:COG2236    31 RPDVIVAIARGGLVPAriladalgvPDLASI--RVSSY----TGTAKRLEEPVVKGPLDEDL-AGKRVLIVDDVADTGRT 103

                          90       100
                  ....*....|....*....|....
gi 1002272054 231 IVAAIDLLVERGVTskqiKVVSAV 254
Cdd:COG2236   104 LEAVRDLLKEAGPA----EVRTAV 123
PRK12560 PRK12560
adenine phosphoribosyltransferase; Provisional
 195-242 1.27e-03

adenine phosphoribosyltransferase; Provisional


Pssm-ID: 183595  Cd Length: 187  Bit Score: 39.00  E-value: 1.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1002272054 195 DEETLQPSIYLNNlpdkIPEGTRVLVVDPMLATGGTIVAAIDLLVERG 242
Cdd:PRK12560   98 GSEYFEGVVYLNG----IEKGDRVAIIDDTLSTGGTVIALIKAIENSG 141
COG1926 COG1926
Predicted phosphoribosyltransferase [General function prediction only];
204-264 5.11e-03

Predicted phosphoribosyltransferase [General function prediction only];


Pssm-ID: 441529  Cd Length: 209  Bit Score: 37.36  E-value: 5.11e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1002272054 204 YLNNLPDKIPEGTRVLVVDPMLATGGTIVAAIDLLVERGVTskqiKVVSA--VAAPPALQKLS 264
Cdd:COG1926   110 YRGGRPPPDLKGRTVILVDDGIATGATMRAALRALRRQGPA----RIVVAvpVAPPDTLEELR 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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