NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1002278493|ref|XP_015643574|]
View 

uncharacterized protein LOC4340922 [Oryza sativa Japonica Group]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
510-663 8.63e-14

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 75.33  E-value: 8.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFL 589
Cdd:COG2319    198 RTLTGHTGAVRSVAFS-----PDGKL----LASGSADGTVRLWDLATGKLLRTLTGHSGSVRSV----AFS--PDGRLLA 262

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002278493  590 SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAW--DGvkgyiaclcRNLHSCNDSGSVlYIWDLKTGARERIITG 663
Cdd:COG2319    263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFspDG---------KLLASGSDDGTV-RLWDLATGKLLRTLTG 328
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
510-663 8.63e-14

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 75.33  E-value: 8.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFL 589
Cdd:COG2319    198 RTLTGHTGAVRSVAFS-----PDGKL----LASGSADGTVRLWDLATGKLLRTLTGHSGSVRSV----AFS--PDGRLLA 262

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002278493  590 SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAW--DGvkgyiaclcRNLHSCNDSGSVlYIWDLKTGARERIITG 663
Cdd:COG2319    263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFspDG---------KLLASGSDDGTV-RLWDLATGKLLRTLTG 328
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 512-666 2.30e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 69.29  E-value: 2.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  512 FLGHTGAILCLAAHHmhaqpdsrtFNRVLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWTHQpwDDCFLSV 591
Cdd:cd00200    131 LRGHTDWVNSVAFSP---------DGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSV----AFSPD--GEKLLSS 195

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002278493  592 GEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVlYIWDLKTGARERIITGTSS 666
Cdd:cd00200    196 SSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLA-------SGSEDGTI-RVWDLRTGECVQTLSGHTN 262
WD40 pfam00400
WD domain, G-beta repeat;
510-553 1.09e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.10  E-value: 1.09e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRtfnrVLISGSFDSTIRVWD 553
Cdd:pfam00400    5 KTLEGHTGSVTSLAFS-----PDGK----LLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 510-553 1.39e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 1.39e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 1002278493   510 RFFLGHTGAILCLAAHHmhaqpdsrtFNRVLISGSFDSTIRVWD 553
Cdd:smart00320    6 KTLKGHTGPVTSVAFSP---------DGKYLASGSDDGTIKLWD 40
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
510-663 8.63e-14

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 75.33  E-value: 8.63e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFL 589
Cdd:COG2319    198 RTLTGHTGAVRSVAFS-----PDGKL----LASGSADGTVRLWDLATGKLLRTLTGHSGSVRSV----AFS--PDGRLLA 262

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002278493  590 SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAW--DGvkgyiaclcRNLHSCNDSGSVlYIWDLKTGARERIITG 663
Cdd:COG2319    263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFspDG---------KLLASGSDDGTV-RLWDLATGKLLRTLTG 328
WD40 COG2319
WD40 repeat [General function prediction only];
512-666 1.57e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 74.18  E-value: 1.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  512 FLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWTHqpwDDCFL-S 590
Cdd:COG2319    158 LTGHSGAVTSVAFS-----PDGKL----LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV----AFSP---DGKLLaS 221

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1002278493  591 VGEDGIVALVSLQTMRVERMFPGHPSYPSMVAW--DGvkGYIAclcrnlhSCNDSGSVlYIWDLKTGARERIITGTSS 666
Cdd:COG2319    222 GSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFspDG--RLLA-------SGSADGTV-RLWDLATGELLRTLTGHSG 289
WD40 COG2319
WD40 repeat [General function prediction only];
510-666 1.15e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 71.48  E-value: 1.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFL 589
Cdd:COG2319    240 RTLTGHSGSVRSVAFS-----PDGRL----LASGSADGTVRLWDLATGELLRTLTGHSGGVNSV----AFS--PDGKLLA 304

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1002278493  590 SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVlYIWDLKTGARERIITGTSS 666
Cdd:COG2319    305 SGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLA-------SGSDDGTV-RLWDLATGELLRTLTGHTG 373
WD40 COG2319
WD40 repeat [General function prediction only];
510-667 2.13e-12

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 70.71  E-value: 2.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWTHqpwDDCFL 589
Cdd:COG2319    114 RTLTGHTGAVRSVAFS-----PDGKT----LASGSADGTVRLWDLATGKLLRTLTGHSGAVTSV----AFSP---DGKLL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  590 -SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAW--DGvkgyiaclcRNLHSCNDSGSVLyIWDLKTGARERIITGTSS 666
Cdd:COG2319    178 aSGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFspDG---------KLLASGSADGTVR-LWDLATGKLLRTLTGHSG 247


                   .
gi 1002278493  667 Q 667
Cdd:COG2319    248 S 248
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 512-666 2.30e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 69.29  E-value: 2.30e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  512 FLGHTGAILCLAAHHmhaqpdsrtFNRVLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWTHQpwDDCFLSV 591
Cdd:cd00200    131 LRGHTDWVNSVAFSP---------DGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSV----AFSPD--GEKLLSS 195

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002278493  592 GEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVlYIWDLKTGARERIITGTSS 666
Cdd:cd00200    196 SSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLA-------SGSEDGTI-RVWDLRTGECVQTLSGHTN 262
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 512-663 6.69e-12

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 68.13  E-value: 6.69e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  512 FLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQIMLPpawthqPWDDCFLSV 591
Cdd:cd00200      5 LKGHTGGVTCVAFS-----PDGKL----LATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAAS------ADGTYLASG 69

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002278493  592 GEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVLyIWDLKTGARERIITG 663
Cdd:cd00200     70 SSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILS-------SSSRDKTIK-VWDVETGKCLTTLRG 133
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 512-656 1.04e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 67.36  E-value: 1.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  512 FLGHTGAILCLAAHHMhaqpdsrtfNRVLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQIMLPPawthqpwDDCFLSV 591
Cdd:cd00200     89 LTGHTSYVSSVAFSPD---------GRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-------DGTFVAS 152

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002278493  592 G-EDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVlYIWDLKTGA 656
Cdd:cd00200    153 SsQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLL-------SSSSDGTI-KLWDLSTGK 210
WD40 COG2319
WD40 repeat [General function prediction only];
510-654 1.55e-11

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 68.01  E-value: 1.55e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRTfnrvLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFL 589
Cdd:COG2319    282 RTLTGHSGGVNSVAFS-----PDGKL----LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV----AFS--PDGKTLA 346

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002278493  590 SVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAclcrnlhSCNDSGSVlYIWDLKT 654
Cdd:COG2319    347 SGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLA-------SGSADGTV-RLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 509-663 3.46e-11

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 65.82  E-value: 3.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  509 ERFFLGHTGAILCLAAHHmhaqpdsrtFNRVLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQIMLppawthQPWDDCF 588
Cdd:cd00200     44 LRTLKGHTGPVRDVAASA---------DGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAF------SPDGRIL 108

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002278493  589 LSVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDGVKGYIAClcrnlhSCNDsgSVLYIWDLKTGARERIITG 663
Cdd:cd00200    109 SSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVAS------SSQD--GTIKLWDLRTGKCVATLTG 175
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 476-651 5.01e-09

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 59.27  E-value: 5.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  476 VYGFHNGDIEVIRFLnllPAAKFGSGGIYPHI----------SERFFLGHTGAILCLAAHhmhaqPDsrtfNRVLISGSF 545
Cdd:cd00200    130 TLRGHTDWVNSVAFS---PDGTFVASSSQDGTiklwdlrtgkCVATLTGHTGEVNSVAFS-----PD----GEKLLSSSS 197

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  546 DSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFLSVGEDGIVALVSLQTMRVERMFPGHPSYPSMVAWDG 625
Cdd:cd00200    198 DGTIKLWDLSTGKCLGTLRGHENGVNSV----AFS--PDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSP 271

                          170       180
                   ....*....|....*....|....*.
gi 1002278493  626 VKGYIAclcrnlhSCNDSGSVlYIWD 651
Cdd:cd00200    272 DGKRLA-------SGSADGTI-RIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
538-666 5.28e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 56.84  E-value: 5.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002278493  538 RVLISGSFDSTIRVWDLDAGTILSVMHHHVAPVKQImlppAWThqPWDDCFLSVGEDGIVALVSLQTMRVERMFPGHPSY 617
Cdd:COG2319     91 RLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSV----AFS--PDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGA 164

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1002278493  618 PSMVAW--DGvkgyiaclcRNLHSCNDSGSVlYIWDLKTGARERIITGTSS 666
Cdd:COG2319    165 VTSVAFspDG---------KLLASGSDDGTV-RLWDLATGKLLRTLTGHTG 205
WD40 pfam00400
WD domain, G-beta repeat;
510-553 1.09e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.10  E-value: 1.09e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1002278493  510 RFFLGHTGAILCLAAHhmhaqPDSRtfnrVLISGSFDSTIRVWD 553
Cdd:pfam00400    5 KTLEGHTGSVTSLAFS-----PDGK----LLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 510-553 1.39e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 1.39e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 1002278493   510 RFFLGHTGAILCLAAHHmhaqpdsrtFNRVLISGSFDSTIRVWD 553
Cdd:smart00320    6 KTLKGHTGPVTSVAFSP---------DGKYLASGSDDGTIKLWD 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH