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Conserved domains on  [gi|1002281947|ref|XP_015645266|]
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myb-related protein 340 [Oryza sativa Japonica Group]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 1000535)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein may be involved in the regulation of gene expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03212 super family cl31985
Transcription repressor MYB5; Provisional
 19-138 2.07e-46

Transcription repressor MYB5; Provisional


The actual alignment was detected with superfamily member PLN03212:

Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 156.78  E-value: 2.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  19 LRRGPWTVEEDLLLVNYIAAHGEGRWNALARCAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHGRWGNRWSK 98
Cdd:PLN03212   23 MKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSL 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1002281947  99 IAQHLPGRTDNEIKNYWRTRVQKhaKHLNCDVNSQQFKDL 138
Cdd:PLN03212  103 IAGRIPGRTDNEIKNYWNTHLRK--KLLRQGIDPQTHKPL 140
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 19-138 2.07e-46

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 156.78  E-value: 2.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  19 LRRGPWTVEEDLLLVNYIAAHGEGRWNALARCAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHGRWGNRWSK 98
Cdd:PLN03212   23 MKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSL 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1002281947  99 IAQHLPGRTDNEIKNYWRTRVQKhaKHLNCDVNSQQFKDL 138
Cdd:PLN03212  103 IAGRIPGRTDNEIKNYWNTHLRK--KLLRQGIDPQTHKPL 140
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 74-117 3.48e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 71.00  E-value: 3.48e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1002281947  74 RGNMTAEEQLLILELHGRWGNRWSKIAQHLPGRTDNEIKNYWRT 117
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
21-70 3.53e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 63.01  E-value: 3.53e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1002281947   21 RGPWTVEEDLLLVNYIAAHGEGRWNALARCAGlKRTGKSCRLRWLNYLRP 70
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 23-68 2.69e-12

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 60.28  E-value: 2.69e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1002281947  23 PWTVEEDLLLVNYIAAHGEGRWNALARCAGlKRTGKSCRLRWLNYL 68
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 11-115 5.64e-11

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 62.88  E-value: 5.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  11 EEAGGGDELRRGPWTVEEDLLLVNYIAAHGEGRWNALARcAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHG 90
Cdd:COG5147    10 QIKLMQTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVAS-LLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDK 88

                          90       100
                  ....*....|....*....|....*
gi 1002281947  91 RWGNRWSKIAQHLPGRTDNEIKNYW 115
Cdd:COG5147    89 ELGTQWSTIADYKDRRTAQQCVERY 113
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 19-138 2.07e-46

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 156.78  E-value: 2.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  19 LRRGPWTVEEDLLLVNYIAAHGEGRWNALARCAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHGRWGNRWSK 98
Cdd:PLN03212   23 MKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSL 102

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1002281947  99 IAQHLPGRTDNEIKNYWRTRVQKhaKHLNCDVNSQQFKDL 138
Cdd:PLN03212  103 IAGRIPGRTDNEIKNYWNTHLRK--KLLRQGIDPQTHKPL 140
PLN03091 PLN03091
hypothetical protein; Provisional
 18-134 1.80e-44

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 157.06  E-value: 1.80e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  18 ELRRGPWTVEEDLLLVNYIAAHGEGRWNALARCAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHGRWGNRWS 97
Cdd:PLN03091   11 KLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWS 90

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1002281947  98 KIAQHLPGRTDNEIKNYWRTRVQKHAKHLNCDVNSQQ 134
Cdd:PLN03091   91 QIAAQLPGRTDNEIKNLWNSCLKKKLRQRGIDPNTHK 127
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 74-117 3.48e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 71.00  E-value: 3.48e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1002281947  74 RGNMTAEEQLLILELHGRWGNRWSKIAQHLPGRTDNEIKNYWRT 117
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 21-68 9.34e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 64.45  E-value: 9.34e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1002281947  21 RGPWTVEEDLLLVNYIAAHGeGRWNALARCAGlKRTGKSCRLRWLNYL 68
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLP-GRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
21-70 3.53e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 63.01  E-value: 3.53e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1002281947   21 RGPWTVEEDLLLVNYIAAHGEGRWNALARCAGlKRTGKSCRLRWLNYLRP 70
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 23-68 2.69e-12

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 60.28  E-value: 2.69e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1002281947  23 PWTVEEDLLLVNYIAAHGEGRWNALARCAGlKRTGKSCRLRWLNYL 68
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
74-117 1.56e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.39  E-value: 1.56e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1002281947   74 RGNMTAEEQLLILELHGRWG-NRWSKIAQHLPGRTDNEIKNYWRT 117
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRN 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 76-117 1.84e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 57.97  E-value: 1.84e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1002281947  76 NMTAEEQLLILELHGRWG-NRWSKIAQHLPGRTDNEIKNYWRT 117
Cdd:cd00167     1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRN 43
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 24-81 5.29e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 57.32  E-value: 5.29e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1002281947  24 WTVEEDLLLVNYIAAHGeGRWNALARCAGlKRTGKSCRLRWLNYLRPDVRRGNMTAEE 81
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEE 56
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 11-115 5.64e-11

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 62.88  E-value: 5.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002281947  11 EEAGGGDELRRGPWTVEEDLLLVNYIAAHGEGRWNALARcAGLKRTGKSCRLRWLNYLRPDVRRGNMTAEEQLLILELHG 90
Cdd:COG5147    10 QIKLMQTKRKGGSWKRTEDEDLKALVKKLGPNNWSKVAS-LLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDK 88

                          90       100
                  ....*....|....*....|....*
gi 1002281947  91 RWGNRWSKIAQHLPGRTDNEIKNYW 115
Cdd:COG5147    89 ELGTQWSTIADYKDRRTAQQCVERY 113
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 78-117 4.88e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 43.07  E-value: 4.88e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1002281947  78 TAEEQLLILELHGRWGNRWSKIAQHLPGRTDNEIKNYWRT 117
Cdd:pfam13921   2 TEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRR 41
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 23-66 4.77e-03

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 34.47  E-value: 4.77e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1002281947  23 PWTVEEDLLLVNYIAAHGEGRWNA--LARCAGLKRTGKSCRLRWLN 66
Cdd:cd11660     2 KWTDEEDEALVEGVEKYGVGNWAKilKDYFFVNNRTSVDLKDKWRN 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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