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Conserved domains on  [gi|1002284700|ref|XP_015646649|]
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alpha-1,2-galactosyltransferase gmh3 isoform X1 [Oryza sativa Japonica Group]

Protein Classification

glycosyltransferase family protein( domain architecture ID 27718)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_tranf_GTA_type super family cl11394
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 79-308 5.70e-20

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


The actual alignment was detected with superfamily member pfam05637:

Pssm-ID: 472172  Cd Length: 238  Bit Score: 87.03  E-value: 5.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700  79 KIAIVTLSDEGAASGSDQDRGrrgrsfrgVLAATARNKRSYAAAHGYGLAVLPA-ASVDPRRPPSWSKVLALRAHLHLHH 157
Cdd:pfam05637   4 RIVILTGSNFGNCENPSGDHE--------YLLKSIKNRVDYARRHGYGFFYVDNsALLPHEMPGVWAKLPAIRQTMLKYP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 158 HHWLFW-NDADTLVTNPDIPLEMILFSVIGHS-----DFDAAP----------------DLILTEDFNGVNAGVFFIRGS 215
Cdd:pfam05637  76 DAEWIWwLDQDALIMNPDLSLQDHILKPEKLTlalikNSPFDPlrrykdtnlvdhgedvMFIISQDWNGLNAGSFLIRNS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 216 KWSEKFLDTWWNLTSFIQ-FGSTKSGDNAALKHLIdhfspeemQEHVRIAKM-----QCLFNSYPwrPTWKSMHrlifhl 289
Cdd:pfam05637 156 QWSKLLLDTWNDPLLREKkKDVFEDDEQSALGYLL--------QKHPTILSKvglvpLRVINSYH--PGAPGLG------ 219

                         250
                  ....*....|....*....
gi 1002284700 290 sttwkgvYSDGDFMVHFAG 308
Cdd:pfam05637 220 -------YKEGDLVVHFAG 231
 
Name Accession Description Interval E-value
Glyco_transf_34 pfam05637
galactosyl transferase GMA12/MNN10 family; This family contains a number of ...
 79-308 5.70e-20

galactosyl transferase GMA12/MNN10 family; This family contains a number of glycosyltransferase enzymes that contain a DXD motif. This family includes a number of C. elegans homologs where the DXD is replaced by DXH. Some members of this family are included in glycosyltransferase family 34.


Pssm-ID: 368535  Cd Length: 238  Bit Score: 87.03  E-value: 5.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700  79 KIAIVTLSDEGAASGSDQDRGrrgrsfrgVLAATARNKRSYAAAHGYGLAVLPA-ASVDPRRPPSWSKVLALRAHLHLHH 157
Cdd:pfam05637   4 RIVILTGSNFGNCENPSGDHE--------YLLKSIKNRVDYARRHGYGFFYVDNsALLPHEMPGVWAKLPAIRQTMLKYP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 158 HHWLFW-NDADTLVTNPDIPLEMILFSVIGHS-----DFDAAP----------------DLILTEDFNGVNAGVFFIRGS 215
Cdd:pfam05637  76 DAEWIWwLDQDALIMNPDLSLQDHILKPEKLTlalikNSPFDPlrrykdtnlvdhgedvMFIISQDWNGLNAGSFLIRNS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 216 KWSEKFLDTWWNLTSFIQ-FGSTKSGDNAALKHLIdhfspeemQEHVRIAKM-----QCLFNSYPwrPTWKSMHrlifhl 289
Cdd:pfam05637 156 QWSKLLLDTWNDPLLREKkKDVFEDDEQSALGYLL--------QKHPTILSKvglvpLRVINSYH--PGAPGLG------ 219

                         250
                  ....*....|....*....
gi 1002284700 290 sttwkgvYSDGDFMVHFAG 308
Cdd:pfam05637 220 -------YKEGDLVVHFAG 231
PLN03181 PLN03181
glycosyltransferase; Provisional
 204-225 3.79e-03

glycosyltransferase; Provisional


Pssm-ID: 215616  Cd Length: 453  Bit Score: 38.98  E-value: 3.79e-03
                          10        20
                  ....*....|....*....|..
gi 1002284700 204 GVNAGVFFIRGSKWSEKFLDTW 225
Cdd:PLN03181  245 ALNAGVFLIRNCQWSLDFMDAW 266
 
Name Accession Description Interval E-value
Glyco_transf_34 pfam05637
galactosyl transferase GMA12/MNN10 family; This family contains a number of ...
 79-308 5.70e-20

galactosyl transferase GMA12/MNN10 family; This family contains a number of glycosyltransferase enzymes that contain a DXD motif. This family includes a number of C. elegans homologs where the DXD is replaced by DXH. Some members of this family are included in glycosyltransferase family 34.


Pssm-ID: 368535  Cd Length: 238  Bit Score: 87.03  E-value: 5.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700  79 KIAIVTLSDEGAASGSDQDRGrrgrsfrgVLAATARNKRSYAAAHGYGLAVLPA-ASVDPRRPPSWSKVLALRAHLHLHH 157
Cdd:pfam05637   4 RIVILTGSNFGNCENPSGDHE--------YLLKSIKNRVDYARRHGYGFFYVDNsALLPHEMPGVWAKLPAIRQTMLKYP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 158 HHWLFW-NDADTLVTNPDIPLEMILFSVIGHS-----DFDAAP----------------DLILTEDFNGVNAGVFFIRGS 215
Cdd:pfam05637  76 DAEWIWwLDQDALIMNPDLSLQDHILKPEKLTlalikNSPFDPlrrykdtnlvdhgedvMFIISQDWNGLNAGSFLIRNS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002284700 216 KWSEKFLDTWWNLTSFIQ-FGSTKSGDNAALKHLIdhfspeemQEHVRIAKM-----QCLFNSYPwrPTWKSMHrlifhl 289
Cdd:pfam05637 156 QWSKLLLDTWNDPLLREKkKDVFEDDEQSALGYLL--------QKHPTILSKvglvpLRVINSYH--PGAPGLG------ 219

                         250
                  ....*....|....*....
gi 1002284700 290 sttwkgvYSDGDFMVHFAG 308
Cdd:pfam05637 220 -------YKEGDLVVHFAG 231
PLN03181 PLN03181
glycosyltransferase; Provisional
 204-225 3.79e-03

glycosyltransferase; Provisional


Pssm-ID: 215616  Cd Length: 453  Bit Score: 38.98  E-value: 3.79e-03
                          10        20
                  ....*....|....*....|..
gi 1002284700 204 GVNAGVFFIRGSKWSEKFLDTW 225
Cdd:PLN03181  245 ALNAGVFLIRNCQWSLDFMDAW 266
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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