|
Name |
Accession |
Description |
Interval |
E-value |
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
282-1044 |
1.44e-163 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 503.70 E-value: 1.44e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 282 EYLQSLNDRQREAAcsdVTI--PLMIVAGPGSGKTSTMVGRVLTLLKEE-FPPSNILAMTFTTAAASEMRDRIGTVVGKA 358
Cdd:COG0210 2 DLLAGLNPEQRAAV---EHPegPLLVLAGAGSGKTRVLTHRIAYLIAEGgVDPEQILAVTFTNKAAREMRERIEALLGRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 359 vAKEIVISTFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQRRAVieaERLLesdKNNGLGDAnkncdgdiknsfKDKAKKW 438
Cdd:COG0210 79 -ARGLWVGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLI---KELL---KELGLDEK------------RFPPREL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 439 QKFVTQAKASGRTPEEYEKKGD-----LTGASILRHYNEILRSCNALDYHDFINSSITLLTKFPEVYDECRNTWQAIVVD 513
Cdd:COG0210 140 LSLISRAKNEGLTPEELAELLAadpewRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 514 EFQDTSAMQYYLLKTLAS-HNRITIVGDEDQSIFSFNGADVSGFDSFRRDFPNHKEVRLSKNYRSTRAIVEAATALIHNN 592
Cdd:COG0210 220 EYQDTNPAQYELLRLLAGdGRNLCVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANN 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 593 TKRQSHKLaETDNPSGNKIIVKECHSEDSQCAFVIDKIIETTSssvEGCHFGKIAVLYRRQITGKAFQASFRNRKIPFNI 672
Cdd:COG0210 300 PGRLGKNL-WTDNGEGEKVRLYVAPDEEEEARFVADEIRELHE---EGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRV 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 673 HG-VAFYRKKVIKAIMAILKTTLpGCDDDApwhqAFKAIL--P----GDKEEKKkiihhIEKISLARKCSFISAATDIFS 745
Cdd:COG0210 376 VGgLRFYERAEIKDLLAYLRLLA-NPDDDV----ALLRILnvPrrgiGAATLER-----LREAAREEGISLLEALRDLGE 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 746 AKVSGTFKRAQITQGRKVLSALDSLSKLVEREQSVSVVISSAGdmlpqkYL--LEKRAIVDADGGkllnedndirsvlqf 823
Cdd:COG0210 446 LAGLSGRAAKALRRFAELLEALRAAAERLPLEELLEALLDESG------YEeeLREEAGEEAERR--------------- 504
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 824 lMDDVSDFLSThfsssvdTSKTEEKGCASTLKAFIDYISLRETENfrsRKEENKNSITLTTIHQSKGLEWDVVFIVQAND 903
Cdd:COG0210 505 -LENLEELVDA-------AARFEERNPGASLEAFLEELALLSDLD---AADEDEDAVTLMTLHAAKGLEFPVVFLVGLEE 573
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 904 SEIPllheYNGTVKEAGStLEEERRLFYVAMTRARKKLYILHV---TVDSNRQLLQPSRFLREIPAHLLEVQGEGTVRRT 980
Cdd:COG0210 574 GLFP----HQRSLDDEEE-LEEERRLFYVAITRARERLYLTYAasrRLWGETQDNEPSRFLDELPEELLEWVRPKAEAAA 648
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1002285891 981 PEQPVNIPFDQPEGDTSVERPMVVRNETSPFPEMDQPCLANDFLKRFEIEDRAIISHIFHQWAK 1044
Cdd:COG0210 649 AAASAAAALPASGAGAAALAAGAAAAAAAAGGGAAVAGAGLGRAAAAGGADGGAAGAGGGLAAV 712
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
284-979 |
1.16e-75 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 265.97 E-value: 1.16e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 284 LQSLNDRQREAacsdVTIPL---MIVAGPGSGKTSTMVGRVLTLLKEE-FPPSNILAMTFTTAAASEMRDRIGTVVGKAV 359
Cdd:PRK11773 7 LDSLNDKQREA----VAAPLgnmLVLAGAGSGKTRVLVHRIAWLMQVEnASPYSIMAVTFTNKAAAEMRHRIEQLLGTSQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 360 AkEIVISTFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQRRAVieaERLLesdKNNGLGDankncdgdiknsfkdkaKKW- 438
Cdd:PRK11773 83 G-GMWVGTFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLL---KRLI---KALNLDE-----------------KQWp 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 439 ----QKFVTQAKASGRTPEEYEKKGDLTGASILRHYNEILRSCN---ALDYHDFINSSITLLTKFPEVYDECRNTWQAIV 511
Cdd:PRK11773 139 prqaQWYINGQKDEGLRPQHIQSYGDPVEQTWLKIYQAYQEACDragLVDFAELLLRAHELWLNKPHILQHYQERFTHIL 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 512 VDEFQDTSAMQYYLLKTLA-SHNRITIVGDEDQSIFSFNGADVSGFDSFRRDFPNHKEVRLSKNYRSTRAIVEAATALIH 590
Cdd:PRK11773 219 VDEFQDTNAIQYAWIRLLAgDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIA 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 591 NNTKRQSHKLAeTDNPSGNKIIVKECHSEDSQCAFVIDKIiettSSSVE-GCHFGKIAVLYRRQITGKAFQASFRNRKIP 669
Cdd:PRK11773 299 NNNGRLGKELW-TDGGDGEPISLYCAFNELDEARFVVERI----KTWQDnGGALSDCAILYRSNAQSRVLEEALLQAGIP 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 670 FNIH-GVAFYRKKVIKAIMAILKtTLPGCDDDApwhqAFKAIL--P----GDkeekkKIIHHIEKISLARKCSFISAATD 742
Cdd:PRK11773 374 YRIYgGMRFFERQEIKDALAYLR-LIANRNDDA----AFERVVntPtrgiGD-----RTLDVVRQTARDRQLTLWQACRA 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 743 IFSAKV-SGtfkRAqitqgrkvLSALDSLSKLVEREQS----------VSVVISSAGdmLPQKYLLEKraivdADGGKLL 811
Cdd:PRK11773 444 LLQEKVlAG---RA--------ASALQRFIELIDALAQetadmplheqTDRVIKDSG--LRAMYEQEK-----GEKGQAR 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 812 NEDndirsvLQFLMDDVSDFlsthfsssvdtSKTEEKGCASTLKAFIDYISLRETEnfrSRKEENKNSITLTTIHQSKGL 891
Cdd:PRK11773 506 IEN------LEELVTATRQF-----------SYPDEDEDLTPLQAFLSHAALEAGE---GQADAHEDAVQLMTLHSAKGL 565
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 892 EWDVVFIVQANDSEIPllheyNGTVKEAGSTLEEERRLFYVAMTRARKKLYILHVTVdsnRQLL------QPSRFLREIP 965
Cdd:PRK11773 566 EFPLVFIVGMEEGLFP-----SQMSLEEGGRLEEERRLAYVGITRAMQKLTLTYAES---RRLYgkevyhRPSRFIREIP 637
|
730
....*....|....*
gi 1002285891 966 AHLL-EVQGEGTVRR 979
Cdd:PRK11773 638 EECVeEVRLRATVSR 652
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
286-964 |
6.03e-75 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 267.21 E-value: 6.03e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 286 SLNDRQREAACsdvtiPLM----IVAGPGSGKTSTMVGRVLTLLKEE-FPPSNILAMTFTTAAASEMRDRIGTVVGKAVA 360
Cdd:COG1074 5 PWTDAQRRALD-----PLGgsvlVEASAGSGKTYTLVARYLRLLLERgLDPEEILVVTFTRAAAAEMRERIRERLAEAAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 361 KEIV-----------------------ISTFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQ---RRAV------------- 401
Cdd:COG1074 80 LEDPdleelararrrlaralenldraaISTIHSFCQRLLREFAFEAGLDPNFELLDDAEAlllEEAVddllreayaplda 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 402 IEAERLLE--SDKNNGLGD---------ANKNCDGDIKNSFKDKAKKWQKFVTQAKA-----SGRTPEEYEKKGDLTGA- 464
Cdd:COG1074 160 LALARLLDafGRDDDSLEElllalyklrSRPDWLEELAELDEALEALREALLKAKEAlaalrEALAAAAAPLLAALLRLl 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 465 -SILRHYNEILRSCNALDYHDFINSSITLLTK--FPEVYDECRNTWQAIVVDEFQDTSAMQYYLLKTLASH-----NRIT 536
Cdd:COG1074 240 aAVLARYERRKRERGLLDFDDLLHRALRLLRDedAPWVAERLRERYRHILVDEFQDTSPLQWEILRRLAGEaladgRTLF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 537 IVGDEDQSIFSFNGADVSGFDSFRRDFPNH---KEVRLSKNYRSTRAIVEA--------------------ATALIHNNT 593
Cdd:COG1074 320 LVGDPKQSIYRFRGADPELFLEARRALEGRvdgERLTLTTNFRSTPEVVDAvnalfaqlmgagfgeipyepVEALRPGAY 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 594 KRQSHKLAETDNPSGNKIIVKECHsedsQCAFVIDKIIE---TTSSSVEGCHFGKIAVLYRRQITGKAFQASFRNRKIPF 670
Cdd:COG1074 400 PAVELWPLEPDDVSEEDAREREAR----AVAARIRRLLAegtTVEGGGRPVRPGDIAVLVRTRSEAAAIARALKAAGIPV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 671 NIHG-VAFYRKKVIKAIMAILKTTL-PgcDDDAPWHQAFKAILPGDKEEkkkiihHIEKISLARKcsfisaATDIFSAkv 748
Cdd:COG1074 476 AASDrLSLFESPEVRDLLALLRALLnP--EDDLALAAVLRSPLFGLSDE------DLAALAADRK------GESLWEA-- 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 749 sgtfkraqITQGRKVLSALDSLSKLVEREQSVSVvissaGDMLpqKYLLEKRAIVDADGG------KLLNedndiRSVLQ 822
Cdd:COG1074 540 --------LRAYERLARALERLRALRELARRLGL-----AELL--ERLLEETGLLERLLAlpggerRLAN-----LLHLD 599
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 823 FLMDDVSDFLSTHFSSsvdtskteekgcastLKAFIDYIS---LRETENFRSRKEENKNSITLTTIHQSKGLEWDVVFIV 899
Cdd:COG1074 600 ELLQLALEYEQTGGPG---------------LAGFLRWLErliEDGGDEEKRRLESDADAVRIMTIHKSKGLEFPVVFLP 664
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002285891 900 QANDseipllheyngtvKEAGSTLEEERRLFYVAMTRARKKLYIlhVTVDSNRQLLQPSRFLREI 964
Cdd:COG1074 665 ALRE-------------RARAEELAEELRLLYVALTRARDRLVL--SGAVKKKDAEKESSWLARR 714
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
287-564 |
7.33e-69 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 232.14 E-value: 7.33e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 287 LNDRQREAACSDVTiPLMIVAGPGSGKTSTMVGRVLTLLKEE-FPPSNILAMTFTTAAASEMRDRIGTVVGKAVAKEIVI 365
Cdd:pfam00580 1 LNPEQRKAVTHLGG-PLLVLAGAGSGKTRVLTERIAYLILEGgIDPEEILAVTFTNKAAREMKERILKLLGKAELSELNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 366 STFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQRRAVIEaerLLESDKNNglgDANKNCDgdiknsfkdkAKKWQKFVTQA 445
Cdd:pfam00580 80 STFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKE---LLEKDRLN---LDPKLLR----------KLELKELISKA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 446 KASGRTPEEYEK-KGDLTG---ASILRHYNEILRSCNALDYHDFINSSITLLTKFPEVYDECRNTWQAIVVDEFQDTSAM 521
Cdd:pfam00580 144 KNRLLSPEELQQgAADPRDklaAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPI 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1002285891 522 QYYLLKTLASHNR-ITIVGDEDQSIFSFNGADVSGFDSFRRDFP 564
Cdd:pfam00580 224 QYRLLKLLAGGHEnLFLVGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
287-965 |
2.01e-68 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 243.98 E-value: 2.01e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 287 LNDRQREAAcSDVTIPLMIVAGPGSGKTSTMVGRVLTLLKE-EFPPSNILAMTFTTAAASEMRDRIGTVVGKAVAKEIVI 365
Cdd:PRK10919 3 LNPGQQQAV-EFVTGPCLVLAGAGSGKTRVITNKIAHLIRGcGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARGLMI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 366 STFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQRRAVIE-AERLLESDKnnglgdankncdgDIKNSFKDKAKKWQK-FVT 443
Cdd:PRK10919 82 STFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKElTEGLIEDDK-------------VLLQQLISTISNWKNdLKT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 444 QAKASGRTPEEYEKkgdlTGASILRHYNEILRSCNALDYHDFINSSITLLTKFPEVYDECRNTWQAIVVDEFQDTSAMQY 523
Cdd:PRK10919 149 PAQAAAGAKGERDR----IFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQY 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 524 YLLKTL-ASHNRITIVGDEDQSIFSFNGADVSGFDSFRRDFPNHKEVRLSKNYRSTRAIVEAATALIHNN----TKRQSH 598
Cdd:PRK10919 225 ELVKLLvGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNphvfEKRLFS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 599 KLAetdnpSGNKIIVKECHSEDSQCAFVIDKIIetTSSSVEGCHFGKIAVLYRRQITGKAFQASFRNRKIPFNIHG-VAF 677
Cdd:PRK10919 305 ELG-----YGDELKVLSANNEEHEAERVTGELI--AHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGgTSF 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 678 YRKKVIKAIMAILKtTLPGCDDDApwhqAFKAILPGDKEE-KKKIIHHIEKISLARKCSFISAATDI-FSAKVSGtfkra 755
Cdd:PRK10919 378 FSRPEIKDLLAYLR-VLTNPDDDS----AFLRIVNTPKREiGPATLQKLGEWAMTRNKSLFTASFDMgLSQTLSG----- 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 756 qitQGRKVLSA----LDSLSKLVEREQSVSVvissagdmlpqkylleKRAIVDADGGKLLNEDNDIRSVLQFLMDDVSDf 831
Cdd:PRK10919 448 ---RGYESLTRfthwLAEIQRLAEREPVAAV----------------RDLIHGIDYESWLYETSPSPKAAEMRMKNVNQ- 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 832 LSTHFSSSVDTSKTEEkgcASTLKAFIDYISLRETENfRSRKEENKNSITLTTIHQSKGLEWDVVFIVQANDSEIPllhe 911
Cdd:PRK10919 508 LFSWMTEMLEGSELDE---PMTLTQVVTRFTLRDMME-RGESEEELDQVQLMTLHASKGLEFPYVYLVGMEEGLLP---- 579
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 912 YNGTVKEagSTLEEERRLFYVAMTRARKKLYIlhvTVDSNR----QLL--QPSRFLREIP 965
Cdd:PRK10919 580 HQSSIDE--DNIDEERRLAYVGITRAQKELTF---TLCKERrqygELVrpEPSRFLLELP 634
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
288-575 |
2.58e-57 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 196.20 E-value: 2.58e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 288 NDRQREAACsDVTIPLMIVAGPGSGKTSTMVGRVLTLLKEEF-PPSNILAMTFTTAAASEMRDRIGTVVGKAVAKEIVIS 366
Cdd:cd17932 1 NPEQREAVT-HPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGvPPERILAVTFTNKAAKEMRERLRKLLGEQLASGVWIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 367 TFHSFCLQlcrthaeklgrtsefiiygngqqrravieaerllesdknnglgdankncdgdiknsfkdkakkwqkfvtqak 446
Cdd:cd17932 80 TFHSFALR------------------------------------------------------------------------ 87
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 447 asgrtpeeyekkgdltgasILRHYneilrscnaLDYHDFINSSITLLTKFPEVYDECRNTWQAIVVDEFQDTSAMQYYLL 526
Cdd:cd17932 88 -------------------ILRRY---------GDFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELL 139
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1002285891 527 KTLAS-HNRITIVGDEDQSIFSFNGADVSGFDSFRRDFPNHKEVRLSKNY 575
Cdd:cd17932 140 KLLAGdGKNLFVVGDDDQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
569-943 |
2.82e-35 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 139.08 E-value: 2.82e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 569 VRLSKNYRSTRAIVEAATALIHNNTKRQS----HKLAETDNPsGNKIIVKECHSEDSQCAFVIDKIIEttsSSVEGCHFG 644
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRATiypkKILAETVED-GEKIKIIEAETEEEEAEWIALEIKK---LVARDEKYN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 645 KIAVLYRRQITGKAFQASFRNRKIPFNIHGV-AFYRKKVIKAIMAILKTTLPGCDDdapwhQAFKAILPGDK-------- 715
Cdd:pfam13361 77 DIAVLTRSNSDADLIEEALKKLGIPYFVVGQtKFFRREEIKDILAYLRLIANKHDS-----ISLKRILNGPKrgignatl 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 716 ---EEKKKIIHH----IEKISLARKCSFISAAT-------DIFSAKVSGT-FKRAQIT----QGRKVLSalDSLSKLVER 776
Cdd:pfam13361 152 eriREYKKRGLRlsdfINPDTLTYGDPFVIALEqdnivvfDVETTGLDTTeDEIIQIAaiklNKKGVVI--ESFERFLRL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 777 EQSV--SVVISSAGDMLPQKYLLEKRAIVDADGGKLLNedndirsvLQFLMDDVSDFLSTHfsssvdtsktEEKGCASTL 854
Cdd:pfam13361 230 KKPVgdSLQVHGFSDEFLQENGETPAEALRDFLEKLEN--------LRELYSILREYDDIE----------ETPEPEDAL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 855 KAFIDYISLRETEnfrSRKEENKNSITLTTIHQSKGLEWDVVFIVQANDSEIPllHEYNgtvKEAGSTLEEERRLFYVAM 934
Cdd:pfam13361 292 RNFLEIATLSNSE---LEGSDIKERIPIMTIHQAKGLEFDTVFLAGLEEGIFP--SYRS---IKDEGNLEEERRLFYVAI 363
|
....*....
gi 1002285891 935 TRARKKLYI 943
Cdd:pfam13361 364 TRAKKRLYI 372
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
298-953 |
3.17e-31 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 133.32 E-value: 3.17e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 298 DVTIPL----MIVAGPGSGKTSTMVGRVLTLLKEEFP--PSNILAMTFTTAAASEMRDRIGTVVGKAV------------ 359
Cdd:TIGR00609 3 PLTIPLngtfLIEASAGTGKTFTIAQLYLRLLLEGGPltVEEILVVTFTNAATEELKTRIRGRIHQALralkaaltsqel 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 360 ----AKEI----------------------VISTFHSFCLQLCRTHAEKLGRTSEFIIYGNGQQRRAVIEAERLLESDKN 413
Cdd:TIGR00609 83 peplKEAIqdekvkqaitrlrnalatmdeaAIYTIHGFCQRMLEQHAFESDEIFDVELIEDESLLLAEITKDFWRRNFYN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 414 ------NGLGDANKNCDGDIKNSFKDKAKKWQ-----KFVTQAKASGRTPEEYE-----------------KKGDLTGAS 465
Cdd:TIGR00609 163 lpfdiaQIVLKTKKSPQAVLTQILADLLLQSYlafpsPPLDLEQLIKWHEQIYKdldkldhavfeeidklnAERNNLFCL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 466 ILRHYNEILR-----------SCNALDYHDFINSSITLLT--KFPEVYDECRNTWQAIVVDEFQDTSAMQYYLLKTLASH 532
Cdd:TIGR00609 243 KDRVFLTLLKevqeelkkekkRRREIGFDDLLSRLETALKsaEGEKLAQAIREQYPIALIDEFQDTDPQQYRIFSKLFIA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 533 NRIT---IVGDEDQSIFSFNGADVSGFDSFRRDFPNHkeVRLSKNYRSTRAIVEAATALIHNNTK--------------R 595
Cdd:TIGR00609 323 QKETslfLIGDPKQAIYSFRGADIFTYLQAKSKADAR--YTLGTNWRSTPALVGSLNKLFSLISNpflekpifipvlahQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 596 QSHKLAETDN---PSGNKIIVKECHSEDSQCAFVidKIIETTSSSVEgcHFGKIAVLYRRqitgkAFQASFRNRKIPFNI 672
Cdd:TIGR00609 401 KNSKGSFVINgqeQPPIHFFTTEVESEGVDDYRQ--TIAQKCAREIA--LWLASAALGLA-----NFIATFGGRPLRAGD 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 673 HGVAFYRKKVIKAIM-AILKTTLPgcdddapwhqafkAILPGDK------EEKKKIIHHIEkiSLARKCSFI----SAAT 741
Cdd:TIGR00609 472 IAVLVRGRKEANQIRkALKKAQIP-------------SVYLSDKssvfatEEAQELLALLE--ALLEPENEGtlraALAS 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 742 DIF--SAKVSGTFKRAQITQGRKVLSALDSLSKLveREQSVSVVIssagdmlpQKYLLEKRAivdadGGKLLNEDNDIRS 819
Cdd:TIGR00609 537 SIFglSALELETLNQDEITWERVVEKFREYHDIW--RKIGVLAMF--------QRLMLEKGI-----GERLLSQPGGERI 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 820 VLQFLmddvsdflstHFSSSVDTSKTEEKGCASTLKAFIDYISLRETENFRSRK-EENKNSITLTTIHQSKGLEWDVV-- 896
Cdd:TIGR00609 602 LTNLL----------HLAELLQEAAHQERNKLSLLRWLEDQISNEEEEEEEIIRlESDAELVKIVTIHKSKGLEYPIVfl 671
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002285891 897 -FIVQANDSEIPLLHEY----NGTVKEAGST----------LEEERRLFYVAMTRARKKLYI----LHVTVDSNRQ 953
Cdd:TIGR00609 672 pFITDAKKSNFASLHDQhsheYQLYDFNQSEenqklarverLAEDLRLLYVALTRAKKQLFIgiapLITSKLSNLA 747
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
819-944 |
8.31e-26 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 104.24 E-value: 8.31e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 819 SVLQFLMDDVSDFLSTHFSSSVDTSKTEEKGCASTLKAFIDYISLRETEN----------FRSRKE----ENKNSITLTT 884
Cdd:cd18807 11 SLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGpvqysdiailVRTNRQarviEEALRVTLMT 90
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 885 IHQSKGLEWDVVFIVQANDSEIPLLHEYNgTVKEAGSTLEEERRLFYVAMTRARKKLYIL 944
Cdd:cd18807 91 IHASKGLEFPVVFIVGLGEGFIPSDASYH-AAKEDEERLEEERRLLYVALTRAKKELYLV 149
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
303-943 |
1.48e-23 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 108.25 E-value: 1.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 303 LMIVAGPGSGKTSTMVGRVLTLLKEEFPPSNILAMTFTTAAASEMRDRIGTVVGKAVAKE---------------IVIST 367
Cdd:TIGR02785 17 ILVSASAGSGKTAVLVERIIRKITRGVDVDRLLVVTFTNAAAREMKERIAEALEKELVQEpnskhlrrqlallntANIST 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 368 FHSFCLQLCRTHAE--------KLGRTSEFIIYGNgQQRRAVIEAERLLE-------------SDKN-NGLGD------- 418
Cdd:TIGR02785 97 LHSFCLKVIRKHYYlldldpsfRILTDTEQLLLIK-EVLDDVFEEEYYKEdkeaffelvdnfsGDRSdDGLRDlilqlyd 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 419 ---ANKNCDG---------DIKNSFKDKAKKWQKFV-------------------------------------------- 442
Cdd:TIGR02785 176 fsrSTPNPEKwlnnlaeayEVKEKFTIESLKLQQQIkellkneleglqeklqralelfmaedglaprlenfqldlqnide 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 443 ------------TQAKASGRTP------------------------EEYEK-----KGDLTGASILRH------------ 469
Cdd:TIGR02785 256 liqeslaqadwnELRKAVAAFKfknlkaakgdeedadlleeadklrEEAKKqleklKTDYFTRSEEDHlrimqemkpvvk 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 470 ------------YNEILRSCNALDYHDFINSSITLLTKFPEVYDECRNTWQA----IVVDEFQDTSAMQYYLLKTLAS-- 531
Cdd:TIGR02785 336 tlvqlvkdfierFGAEKREKNILDFSDLEHYALQILTNENESPSEAAEFYREkfheVLVDEYQDTNLVQESILQLVKRgp 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 532 ---HNRItIVGDEDQSIFSFNGADVSGF----DSFRRDFPNH-KEVRLSKNYRSTRAIVEA------------------- 584
Cdd:TIGR02785 416 eeeGNLF-MVGDVKQSIYRFRQADPLLFlekyHRFAQEGEEHgKRIDLAENFRSRAEVLDTtnflfkqlmdeevgeidyd 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 585 -ATALIHNNTKRQSHKLAETDNPSGNKIIVKECHSEDSQCAFVID----------------------KIIETTSSSVEGC 641
Cdd:TIGR02785 495 eEAQLKFGAAKYPENPDNKTEELLYEKLLIEEAEEEEIDEEAEILdkaqqeatmvaerikalikegfKVYDKKTGTYRPV 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 642 HFGKIAVLYRRQITGKAFQASFRNRKIPFNIHGVAFYRKKV-IKAIMAILKtTLPGCDDDAPWHQAFKAILPGDKEEKkk 720
Cdd:TIGR02785 575 TYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTeVRVMLSLLR-VIDNPYQDIPLVAVLRSPIVGFDENE-- 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 721 iihhIEKISLARK-CSFISAATDIFSAKVSGTfkraqiTQGRKVLSALDSLSKLveREQSVSVVISsagDMLPQKYllEK 799
Cdd:TIGR02785 652 ----LALIRLENKdSSYYEAVKDYVKAGLIED------ELYEKLNTFLDSLQKW--REFARTHSVS---ELIWKIY--ND 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 800 RAIVDADGGklLNEDNDIRSVLQFLMDDVSDFLSTHFsssvdtskteeKGcastLKAFIDYIS-LRET-ENFRSRK--EE 875
Cdd:TIGR02785 715 TGYYDYVGG--LPGGKQRQANLYALYERARQYESTSF-----------KG----LFQFIRFIErMQERqKDLASAVavGE 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 876 NKNSITLTTIHQSKGLEWDVVFIV------QANDSEIP-LLHEYNGT----------------VKEAG------STLEEE 926
Cdd:TIGR02785 778 AENAVRLMTIHKSKGLEFPVVFVLgmgkqfNKQDLNSSyLLDRQLGLgikyidpqerlsypslPKVAIkqkmkrELLSEE 857
|
890
....*....|....*..
gi 1002285891 927 RRLFYVAMTRARKKLYI 943
Cdd:TIGR02785 858 MRVLYVALTRAKEKLIL 874
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
440-972 |
1.47e-18 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 92.12 E-value: 1.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 440 KFVTQAKASGRTPEEYEKKGDLTG------ASILRHYNEILRScNALDYHDFINSSITLLTKFPEVYDecrntwQAIVVD 513
Cdd:COG3857 119 ELITELKRYGITPEDLEEAAELLKeklrdlALIYEAYEEKLAG-RYIDSEDLLRLLAEKLEKSEFLEG------AEIYID 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 514 EFQDTSAMQYYLLKTLASHNRITIVG----DEDQSIFSFNGadvsgfDSFRRDFPNHKEVRLSKNYRSTRAIVEAATALI 589
Cdd:COG3857 192 GFTDFTPQELELLEALLKKAKEVTITltldPDELDLFSATG------ETYERLLELAKENGVEVEFKKSPELAHLERNLF 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 590 HNNTKRQShklaetdnpsgNKIIVKECHSEDSQCAFVIDKIIETTSSsvEGCHFGKIAVLYRR-QITGKAFQASFRNRKI 668
Cdd:COG3857 266 AYPPEEEP-----------EGIEIIEAANRRAEVEAVAREIRRLVRE--EGYRYRDIAVVVRDlEAYAPLIERVFAEYGI 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 669 PFNI-HGVAFYRKKVIKAIMAILKTTLPGCDddapwHQAFKAIL------PGDKEEkkkiIHHIEKISLARKCSFISAAT 741
Cdd:COG3857 333 PYFIdEKRPLSHHPLVELILSLLELVRSNFR-----YEDVFRLLktgllrPLSREE----IDRLENYVLAYGIRGRRWLE 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 742 DIFSAKVSGT----FKRAQITQGRK-VLSALDSLSKLVEREQSVSVVISSAGDMLPQKYLLEK-RAIVDADGGKLLNEDN 815
Cdd:COG3857 404 RYLEEEEELTdeeeEDLERLNELRDrLLEPLLPLRERLKKAKTVREWAEALYEFLEELGVPEKlEEWREAEEAGDLEEAR 483
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 816 DIRSVLQFLMDDVSDFLSTHFSSSVdtskteekgcasTLKAFIDYIS--LRETEnfRSRKEENKNSITLTTIHQSKGLEW 893
Cdd:COG3857 484 EHEQAWNALIELLDELVEVLGDEKL------------SLEEFLRILEsgLEELT--FGLIPPSLDQVQVGGLDRARGLDF 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 894 DVVFIVQANDSEIPLLHEYNG--------TVKEAGSTL--------EEERRLFYVAMTRARKKLYILHVTVDSNRQLLQP 957
Cdd:COG3857 550 KAVFVLGLNEGVFPARPREDGllsdeereRLNELGLELpptsrerlLEERFLFYRALTRASERLYLSYPLADEEGKALLP 629
|
570
....*....|....*
gi 1002285891 958 SRFLREIPAHLLEVQ 972
Cdd:COG3857 630 SPLIDRLRELFPELE 644
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
285-592 |
1.16e-17 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 88.47 E-value: 1.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 285 QSLNDRQREAacsdVTI---PLMIVAGPGSGKTSTMVGRVLTLLK-EEFPPSNILAMTFTTAAASEMRDRIGTVVGkavA 360
Cdd:PRK11054 195 SPLNPSQARA----VVNgedSLLVLAGAGSGKTSVLVARAGWLLArGQAQPEQILLLAFGRQAAEEMDERIRERLG---T 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 361 KEIVISTFHSFCLQLCRTHAEKLGRTSEFIIygNGQQRRAVIEAERLLESDKNnglgdankncdgdiknsfKDKAKKWQK 440
Cdd:PRK11054 268 EDITARTFHALALHIIQQGSKKVPVISKLEN--DSKARHALLIAEWRKQCSEK------------------KAQAKGWRQ 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 441 FVT------------------QAKASGR---------------------TPEEY----EKKGDLTgASILRHYNEILRSC 477
Cdd:PRK11054 328 WLTeelqwdvpegnfwddeklQRRLASRlerwvslmrmhggsqaemiaqAPEEVrdlfQKRLKLM-APLLKAWKKALKAE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 478 NALDYHDFINSSITLLTK--FpevydecRNTWQAIVVDEFQDTSAMQYYLLKTLASHNRIT---IVGDEDQSIFSFNGAD 552
Cdd:PRK11054 407 NAVDFSGLIHQAVNYLEKgrF-------ISPWKHILVDEFQDISPQRAALLAALRKQNSQTtlfAVGDDWQAIYRFSGAD 479
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1002285891 553 VSGFDSFRRDFPNHKEVRLSKNYRSTRAIVEAATALIHNN 592
Cdd:PRK11054 480 LSLTTAFHERFGEGDRCHLDTTYRFNSRIGEVANRFIQQN 519
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
307-944 |
4.84e-17 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 86.95 E-value: 4.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 307 AGPGSGKTSTMVGRVLTLLKEEFPPSNILAMTFTTAAASEMRDRI-----------GTVVGKAVAK-------------- 361
Cdd:PRK13909 5 ASAGSGKTFALSVRFLALLFKGANPSEILALTFTKKAANEMKERIidtllnlekekEESELNELEEklglskeellnkrd 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 362 ---------EIVISTFHSFCLQLCRTHAEKLGRTSEFIIygnGQQRRAVIEaERLLESDKNNGLGD----ANKNCDGDIK 428
Cdd:PRK13909 85 kvyqeflnsELKISTIDAFFQKILRKFCLNLGLSPDFSI---KEDTKEELN-EKFLSALSKEELLEllafIKQCESKKNN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 429 NSFKDKAKKWQKFVT-QAKASGRTPEEYEKKGDLtgaSILRHYNEILRSCNAL-----------DYHDFINSSITLLTK- 495
Cdd:PRK13909 161 SFFELLEKLYEKNNElKLFEKAKNPIEFDEEKFL---EELRSLKQQIQSIETAsknakkafkkeDFEELLNSSKTWLEKe 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 496 ------------------------------------------FPEVYDECRNTWQA------------------------ 509
Cdd:PRK13909 238 seyryfkklyneeldaefeelknalkryydakenyklsklfkLLQLYKEAKNELNKkknaldfddiskkvyellgeeeid 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 510 --------------IVVDEFQDTSAMQYYLLKTL----------ASHNRITIVGDEDQSIFSFNGADVSGFDSFRRDFPN 565
Cdd:PRK13909 318 kdflyfrldskishILIDEFQDTSVLQYKILLPLideiksgegqKKFRSFFYVGDVKQSIYRFRGGKKELFDKVSKDFKQ 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 566 HKEVrLSKNYRSTRAIVEAATALIHNNTKRQSHKLAETDnpsgnkiiVKECHSEDSQCAFVIDKIIETTSSSVE-----G 640
Cdd:PRK13909 398 KVDN-LDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQH--------KSGGYVEVVEVADESEELLEQLLQEIQfllekG 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 641 CHFGKIAVLyrrqitgkafqaSFRNRKI---------PFNIHGVAFYRKKVI-----KAImailkttlpgcdddapwHQA 706
Cdd:PRK13909 469 IDPDDIAIL------------CWTNDDAleikeflqeQFGIKAVTESSAKLInqpevKAL-----------------IEA 519
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 707 FKAILPGDKEEKKKIIHHIEKiSLARKCSFISAatdifsakvsgtfkraqitqgrkvlsaldslsklverEQSVSVVIss 786
Cdd:PRK13909 520 LKYCLFGEEIYKHNVLKLLGK-EPDKIPSFLPK-------------------------------------EESVAEFV-- 559
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 787 agdmlpqKYLLEKRAIVDADGGKLLNEDNDirsvlqflMDDVSDFLSTHFSSSVDTSKTEEKGcastlkafidyislret 866
Cdd:PRK13909 560 -------KKLIEELKLYDENLLKFLELASG--------YEDIEEFLFKLEPCDKEIASEESKG----------------- 607
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 867 enfrsrkeenknsITLTTIHQSKGLEWDVVfIV-------QANDSeiPLLHEYNGTV----------------------- 916
Cdd:PRK13909 608 -------------VQIMTVHKSKGLEFEHV-IVcdrlgkpNSDSS--NLLFEYDGIElwqiyyrikgrenfdkdyarale 671
|
810 820
....*....|....*....|....*...
gi 1002285891 917 KEAGSTLEEERRLFYVAMTRARKKLYIL 944
Cdd:PRK13909 672 KEKALKYEEEINVLYVAFTRAKNSLIVV 699
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
510-630 |
1.66e-16 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 84.92 E-value: 1.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 510 IVVDEFQDTSAMQYYLLKTLASHNRITIVGDEDQSIFSFNGAdvsgfDSFRR-----DFPNHKEVRLSKNYRSTRAIVEA 584
Cdd:COG3973 473 VVVDEAQDLSPMQWRVLKRRFPSASFTIVGDLAQAIHPYRGA-----ESWEEvleplGGDRARLVELTKSYRSTAEIMEF 547
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1002285891 585 ATALIHnntkrqsHKLAETDNP-----SGNKIIVKECHSEDSQCAFVIDKI 630
Cdd:COG3973 548 ANRVLR-------AAGPDLPPPesvrrHGEPPRVVRVPSEAELAAAVVEAV 591
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
291-548 |
1.66e-14 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 71.48 E-value: 1.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 291 QREAACSDVTIPLMIV-AGPGSGKTSTMVGRVLTLLKEEFPPSNILAMTFTTAAASEMRDRIGtvvgkavakeIVISTFH 369
Cdd:pfam13245 1 QREAVRTALPSKVVLLtGGPGTGKTTTIRHIVALLVALGGVSFPILLAAPTGRAAKRLSERTG----------LPASTIH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 370 sfclqlcrthaeklgrtsefiiygngqqrravieaeRLLESDknnglgdankncdgdiknsfkdkakkwqkfvtqakasG 449
Cdd:pfam13245 71 ------------------------------------RLLGFD-------------------------------------D 77
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 450 RTPEEYEKKGDltgasilrhyneilrscNALDYhdfinssitlltkfpevydecrntwQAIVVDEFQDTSA-MQYYLLKT 528
Cdd:pfam13245 78 LEAGGFLRDEE-----------------EPLDG-------------------------DLLIVDEFSMVDLpLAYRLLKA 115
|
250 260
....*....|....*....|
gi 1002285891 529 LASHNRITIVGDEDQSIFSF 548
Cdd:pfam13245 116 LPDGAQLLLVGDPDQLPSVG 135
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
880-944 |
1.08e-12 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 63.75 E-value: 1.08e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1002285891 880 ITLTTIHQSKGLEWDVVFIVQANDSEIPLLHEYngtvkeagstleeeRRLFYVAMTRARKKLYIL 944
Cdd:pfam13538 2 AYALTVHKAQGSEFPAVFLVDPDLTAHYHSMLR--------------RRLLYTAVTRARKKLVLV 52
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
577-664 |
3.22e-12 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 65.33 E-value: 3.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 577 STRAIVEAATALIHNNTKRQSHKLaETDNPSGNKIIVKECHSEDSQCAFVIDKIIEttSSSVEGCHFGKIAVLYRRQITG 656
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPL-KAGNKSGGPVELLLAKDEADEAKAIADEIKR--LIESGPVQYSDIAILVRTNRQA 77
|
....*...
gi 1002285891 657 KAFQASFR 664
Cdd:cd18807 78 RVIEEALR 85
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
484-575 |
1.43e-10 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 59.81 E-value: 1.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 484 DFINSSITLLTKFPEVYDECRNtwqaIVVDEFQDTSAMQYYLLKTLAS-HNRITIVGDEDQSIFSFNGADVSGFD----- 557
Cdd:cd17914 28 NGEPGRILLVTPTNKAAAQLDN----ILVDEAAQILEPETSRLIDLALdQGRVILVGDHDQLGPVWRGAVLAKICneqsl 103
|
90
....*....|....*...
gi 1002285891 558 SFRRDFPNHKEVRLSKNY 575
Cdd:cd17914 104 FTRLVRLGVSLIRLQVQY 121
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
867-956 |
1.53e-10 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 65.24 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 867 ENFRSRKEENKNSITLTTIHQSKGLEWDVVFIVQANDSEIpllheyngtvkeaGSTLEEERRLFYVAMTRARKKLYILHV 946
Cdd:COG3972 476 ARSDPNFFWKDGGVTISTIHRAKGLEAPVVIIVGLDQLAK-------------GESLERLRNLLYVAMTRARGWLVVSGS 542
|
90
....*....|
gi 1002285891 947 TvDSNRQLLQ 956
Cdd:COG3972 543 G-ESMAELYD 551
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
302-402 |
6.77e-09 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 55.18 E-value: 6.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 302 PLMIVAGPGSGKTSTMVGRVLTLLKEE-FPPSNILAMTFTTAAASEMRdrigtvvgkavakEIVISTFHSFCLQLCRTHA 380
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKnGEPGRILLVTPTNKAAAQLD-------------NILVDEAAQILEPETSRLI 67
|
90 100
....*....|....*....|..
gi 1002285891 381 EKLGRTSEFIIYGNGQQRRAVI 402
Cdd:cd17914 68 DLALDQGRVILVGDHDQLGPVW 89
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
858-943 |
3.14e-08 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 52.05 E-value: 3.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 858 IDYISLRETENFRSRKEENKNSITLTTIHQSKGLEWDVVFIVqandseiplLHEYNgtvkeagstlEEERRLFYVAMTRA 937
Cdd:cd18786 21 RDRAYLNQYLQGLSLDEFDLQLVGAITIDSSQGLTFDVVTLY---------LPTAN----------SLTPRRLYVALTRA 81
|
....*.
gi 1002285891 938 RKKLYI 943
Cdd:cd18786 82 RKRLVI 87
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
883-943 |
4.10e-08 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 51.41 E-value: 4.10e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002285891 883 TTIHQSKGLEWDVVFIVQanDSEIPLLheyngtvkeagstleeERRLFYVAMTRARKKLYI 943
Cdd:cd18809 36 MTIHKSQGSEFDRVIVVL--PTSHPML----------------SRGLLYTALTRARKLLTL 78
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
883-943 |
7.86e-07 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 53.06 E-value: 7.86e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002285891 883 TTIHQSKGLEWDVVFIVqANDSEIPLLHeyngtvkeagstleeeRRLFYVAMTRARKKLYI 943
Cdd:COG0507 445 ITVHKSQGSTFDRVILV-LPSEHSPLLS----------------RELLYTALTRARELLTL 488
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
512-588 |
1.57e-05 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 49.58 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 512 VDEFQDTSAMQYYLLKTLASH---NRITIVGDEDQSIFSFNGADVSGFDSFRRDFPNHkeVRLSKNYRSTRAIVEAATAL 588
Cdd:PRK10876 383 IDEFQDTDPQQYRIFRRIYRHqpeTALLLIGDPKQAIYAFRGADIFTYMKARSEVSAH--YTLDTNWRSAPGMVNSVNKL 460
|
|
| DNA2 |
COG1112 |
Superfamily I DNA and/or RNA helicase [Replication, recombination and repair]; |
867-964 |
4.23e-05 |
|
Superfamily I DNA and/or RNA helicase [Replication, recombination and repair];
Pssm-ID: 440729 [Multi-domain] Cd Length: 819 Bit Score: 47.82 E-value: 4.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 867 ENFRSRKEENKNSITLTTIHQSKGLEWDVVFI--VQANDSEIPllheyngtvKEAGStLEEERRLFYVAMTRARKKLYIL 944
Cdd:COG1112 725 ELLREALGDGLEPVFVGTVDRFQGDERDVIIFslVYSNDEDVP---------RNFGF-LNGGPRRLNVAVSRARRKLIVV 794
|
90 100
....*....|....*....|..
gi 1002285891 945 H--VTVDSNRQLLQPSRFLREI 964
Cdd:COG1112 795 GsrELLDSDPSTPALKRLLEYL 816
|
|
| SF1_C_Upf1 |
cd18808 |
C-terminal helicase domain of Upf1-like family helicases; The Upf1-like helicase family ... |
871-964 |
6.81e-05 |
|
C-terminal helicase domain of Upf1-like family helicases; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), and similar proteins. They are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350195 [Multi-domain] Cd Length: 184 Bit Score: 44.92 E-value: 6.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 871 SRKEENKNSITLTTIHQSKGLEWDVVFI--VQANDSEIPLLHeyngtvkeagstLEEERRLfYVAMTRARKKLYILHvtv 948
Cdd:cd18808 102 RKRGGLLEDVEVGTVDNFQGREKDVIILslVRSNESGGSIGF------------LSDPRRL-NVALTRAKRGLIIVG--- 165
|
90
....*....|....*.
gi 1002285891 949 dsNRQLLQPSRFLREI 964
Cdd:cd18808 166 --NPDTLSKDPLWKKL 179
|
|
| DEXXQc_Helz-like |
cd18038 |
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and ... |
286-359 |
1.39e-04 |
|
DEXXQ/H-box helicase domain of Helz-like helicase; This subfamily contains HELZ, Mov10L1, and similar proteins. Helicase with zinc finger (HELZ) acts as a helicase that plays a role in RNA metabolism during development. Moloney leukemia virus 10-like protein 1 (Mov10L1) binds Piwi-interacting RNA (piRNA) precursors to initiate piRNA processing. All are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350796 [Multi-domain] Cd Length: 229 Bit Score: 44.53 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 286 SLNDRQREAACSDVT-----IPLMIVAGPGSGKTSTMVGRVLTLLKeEFPPSNILAMTFTTAAASEMRDR-IGTVVGKAV 359
Cdd:cd18038 1 ELNDEQKLAVRNIVTgtsrpPPYIIFGPPGTGKTVTLVEAILQVLR-QPPEARILVCAPSNSAADLLAERlLNALVTKRE 79
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
287-352 |
4.78e-04 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 44.20 E-value: 4.78e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1002285891 287 LNDRQREAAC-----SDVTIplmIVAGPGSGKTsTMVGRVLTLLKEEFPpsNILAMTFTTAAASEMRDRIG 352
Cdd:COG0507 125 LSDEQREAVAlalttRRVSV---LTGGAGTGKT-TTLRALLAALEALGL--RVALAAPTGKAAKRLSESTG 189
|
|
| Viral_helicase1 |
pfam01443 |
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated ... |
883-944 |
5.77e-04 |
|
Viral (Superfamily 1) RNA helicase; Helicase activity for this family has been demonstrated and NTPase activity. This helicase has multiple roles at different stages of viral RNA replication, as dissected by mutational analysis.
Pssm-ID: 366646 [Multi-domain] Cd Length: 227 Bit Score: 42.75 E-value: 5.77e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002285891 883 TTIHQSKGLEWDVVFIVQANDSeipllheyngtvkeAGSTLEEERRLFYVAMTRARKKLYIL 944
Cdd:pfam01443 179 TTVHEVQGLTFDSVTLVLDTDT--------------DLLIISDSPEHLYVALTRHRKSLHIL 226
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
865-937 |
9.44e-04 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 43.42 E-value: 9.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002285891 865 ETENFRSRKEENKNSITLTTIHQSKGLEWDVV---FI----VQAN------DSEIPLLHEYNGtvKEAGSTLEEER---- 927
Cdd:PRK10876 721 QASSQQLRLESDKHLVQIVTIHKSKGLEYPLVwlpFItnfrVQDQafyhdrHSFEAVLDLNAA--EESVALAEEERlaed 798
|
90
....*....|.
gi 1002285891 928 -RLFYVAMTRA 937
Cdd:PRK10876 799 lRLLYVALTRS 809
|
|
| AAA_12 |
pfam13087 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
871-944 |
3.69e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.
Pssm-ID: 463780 [Multi-domain] Cd Length: 196 Bit Score: 39.84 E-value: 3.69e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002285891 871 SRKEENKNSITLTTIHQSKGLEWDVVFI--VQANDSeipllheyngtvKEAGsTLEEERRLfYVAMTRARKKLYIL 944
Cdd:pfam13087 131 KRKLGGKLEIEVNTVDGFQGREKDVIIFscVRSNEK------------GGIG-FLSDPRRL-NVALTRAKRGLIIV 192
|
|
| |
