NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1443094275|ref|XP_015649663|]
View 

non-structural maintenance of chromosomes element 4 homolog B [Oryza sativa Japonica Group]

Protein Classification

non-structural maintenance of chromosomes element 4( domain architecture ID 10555400)

non-structural maintenance of chromosomes element 4 is a component of the SMC5-SMC6 complex, which promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Nse4_C pfam08743
Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges ...
 239-327 2.08e-27

Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges the heads of Smc5 and Smc6. This is the C-terminal domain of Nse4 that interacts with the head domain of Smc5.


:

Pssm-ID: 462585  Cd Length: 89  Bit Score: 103.76  E-value: 2.08e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443094275 239 CVKLENLILNRQSFAQTVENIFALSFLVKDGRVEIDVDDKGNHFVVPRNAPAAELITSREVINSQYVFRFDTKDWKIMEG 318
Cdd:pfam08743   1 PINLFKFVINPKSFAQTVENLFYLSFLVKDGRVGIELDEDGLPVLEPVAPPEEEEAKEGGVSRNQAVFSLDMKTWKELIE 80


                  ....*....
gi 1443094275 319 VVEPGDELM 327
Cdd:pfam08743  81 AFDITEPMI 89
 
Name Accession Description Interval E-value
Nse4_C pfam08743
Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges ...
 239-327 2.08e-27

Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges the heads of Smc5 and Smc6. This is the C-terminal domain of Nse4 that interacts with the head domain of Smc5.


Pssm-ID: 462585  Cd Length: 89  Bit Score: 103.76  E-value: 2.08e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443094275 239 CVKLENLILNRQSFAQTVENIFALSFLVKDGRVEIDVDDKGNHFVVPRNAPAAELITSREVINSQYVFRFDTKDWKIMEG 318
Cdd:pfam08743   1 PINLFKFVINPKSFAQTVENLFYLSFLVKDGRVGIELDEDGLPVLEPVAPPEEEEAKEGGVSRNQAVFSLDMKTWKELIE 80


                  ....*....
gi 1443094275 319 VVEPGDELM 327
Cdd:pfam08743  81 AFDITEPMI 89
COG5125 COG5125
Uncharacterized conserved protein [Function unknown];
191-317 1.51e-06

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227454 [Multi-domain]  Cd Length: 259  Bit Score: 49.23  E-value: 1.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443094275 191 RRKRVARRLFdrfpSKPAGLYETTPDLDERN-DTDKNMAVMFKLLRKNKCVKLENLILNRQSFAQTVENIFALSFLVKDG 269
Cdd:COG5125   133 RRAQSQRSRQ----TLPETEVPTNITRQEDSvEEPKILAQISRLLAEKGRTNYFKFIIDPRSFSKTIENLFYLSFLLKEG 208

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1443094275 270 RVEIDVDDKGNHFVVPRNapaaelitSREVINSQYVFRFDTKDW-KIME 317
Cdd:COG5125   209 KAFLEFDEDGTLYVVSEG--------SEGASTGHLVVEMTYDEYlRIVE 249
 
Name Accession Description Interval E-value
Nse4_C pfam08743
Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges ...
 239-327 2.08e-27

Nse4 C-terminal; Nse4 is the kleisin component of the Smc5/6 DNA repair complex. It bridges the heads of Smc5 and Smc6. This is the C-terminal domain of Nse4 that interacts with the head domain of Smc5.


Pssm-ID: 462585  Cd Length: 89  Bit Score: 103.76  E-value: 2.08e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443094275 239 CVKLENLILNRQSFAQTVENIFALSFLVKDGRVEIDVDDKGNHFVVPRNAPAAELITSREVINSQYVFRFDTKDWKIMEG 318
Cdd:pfam08743   1 PINLFKFVINPKSFAQTVENLFYLSFLVKDGRVGIELDEDGLPVLEPVAPPEEEEAKEGGVSRNQAVFSLDMKTWKELIE 80


                  ....*....
gi 1443094275 319 VVEPGDELM 327
Cdd:pfam08743  81 AFDITEPMI 89
COG5125 COG5125
Uncharacterized conserved protein [Function unknown];
191-317 1.51e-06

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227454 [Multi-domain]  Cd Length: 259  Bit Score: 49.23  E-value: 1.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443094275 191 RRKRVARRLFdrfpSKPAGLYETTPDLDERN-DTDKNMAVMFKLLRKNKCVKLENLILNRQSFAQTVENIFALSFLVKDG 269
Cdd:COG5125   133 RRAQSQRSRQ----TLPETEVPTNITRQEDSvEEPKILAQISRLLAEKGRTNYFKFIIDPRSFSKTIENLFYLSFLLKEG 208

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1443094275 270 RVEIDVDDKGNHFVVPRNapaaelitSREVINSQYVFRFDTKDW-KIME 317
Cdd:COG5125   209 KAFLEFDEDGTLYVVSEG--------SEGASTGHLVVEMTYDEYlRIVE 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH