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Conserved domains on  [gi|1002291824|ref|XP_015650259|]
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tyrosine--tRNA ligase 1, cytoplasmic [Oryza sativa Japonica Group]

Protein Classification

tyrosine--tRNA ligase( domain architecture ID 10015222)

tyrosine--tRNA ligase catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)

CATH:  1.10.240.10|3.40.50.620
EC:  6.1.1.1
Gene Ontology:  GO:0004831|GO:0006437|GO:0005524|GO:0003723
PubMed:  12458790|10447505|8274143|1852601|2053131|11590011|10704480

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00126 PTZ00126
tyrosyl-tRNA synthetase; Provisional
 32-380 0e+00

tyrosyl-tRNA synthetase; Provisional


:

Pssm-ID: 240282 [Multi-domain]  Cd Length: 383  Bit Score: 652.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00126   35 LSLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSGRMHIAQGILKAINVNKLTKAGCVFVFWVADWFALLNN 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAA 191
Cdd:PTZ00126  115 KMGGDLEKIRKVGEYFIEVWKAAGMDMDNVRFLWASEEINKNPNDYWLRVMDIARSFNITRIKRCSQIMGRSEGDEQPCA 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00126  195 QILYPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKSDPNSAIFMEDSEE 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQ 351
Cdd:PTZ00126  275 DVNRKIKKAYCPPGVIEGNPILAYFKSIVFPAFNSFTVLRKEKNGGDVTYTTYEELEKDYLSGALHPGDLKPALAKYLNL 354

                         330       340
                  ....*....|....*....|....*....
gi 1002291824 352 ILQPIRDHFNNNSEAKILLNTVKKYRVTN 380
Cdd:PTZ00126  355 MLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
 
Name Accession Description Interval E-value
PTZ00126 PTZ00126
tyrosyl-tRNA synthetase; Provisional
 32-380 0e+00

tyrosyl-tRNA synthetase; Provisional


Pssm-ID: 240282 [Multi-domain]  Cd Length: 383  Bit Score: 652.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00126   35 LSLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSGRMHIAQGILKAINVNKLTKAGCVFVFWVADWFALLNN 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAA 191
Cdd:PTZ00126  115 KMGGDLEKIRKVGEYFIEVWKAAGMDMDNVRFLWASEEINKNPNDYWLRVMDIARSFNITRIKRCSQIMGRSEGDEQPCA 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00126  195 QILYPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKSDPNSAIFMEDSEE 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQ 351
Cdd:PTZ00126  275 DVNRKIKKAYCPPGVIEGNPILAYFKSIVFPAFNSFTVLRKEKNGGDVTYTTYEELEKDYLSGALHPGDLKPALAKYLNL 354

                         330       340
                  ....*....|....*....|....*....
gi 1002291824 352 ILQPIRDHFNNNSEAKILLNTVKKYRVTN 380
Cdd:PTZ00126  355 MLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
tRNA-synt_1b pfam00579
tRNA synthetases class I (W and Y);
59-354 1.85e-71

tRNA synthetases class I (W and Y);


Pssm-ID: 395461 [Multi-domain]  Cd Length: 292  Bit Score: 225.23  E-value: 1.85e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  59 QKKPVPICYDGFEPSGRMHIAqGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYM---IEIWRAAG 135
Cdd:pfam00579   1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaIKAQLACG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 136 MNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGR-NDSDELTAAQIFYPCMQCADIFFLKADICQLG 214
Cdd:pfam00579  80 LDPEKAEIVNNSDWLEHL--ELAWLLRDLGKHFSLNRMLQFKDVKKRlEQGPGISLGEFTYPLLQAYDILLLKADLQPGG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 215 MDQRKVNVLAREYCTDIKRK--NKPIILSHHMLPGFkEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvdGNPC 292
Cdd:pfam00579 158 SDQWGNIELGRDLARRFNKKifKKPVGLTNPLLTGL-DGGKKMSKSAGNSAIFLDDDPESVYKKIQKAYTDPDR--EVRK 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002291824 293 LEYIKYIVFPwfemFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:pfam00579 235 DLKLFTFLSN----EEIEILEAELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
TyrRS_core cd00805
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ...
 67-352 1.40e-35

catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.


Pssm-ID: 173902 [Multi-domain]  Cd Length: 269  Bit Score: 131.19  E-value: 1.40e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSG-RMHIAQGIVkTINVNKMVRAGCKVKIWIADWFAQLNNKMG-------GDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:cd00805     4 YIGFDPTApSLHLGHLVP-LMKLRDFQQAGHEVIVLIGDATAMIGDPSGkseerklLDLELIRENAKYYKKQLKAILDFI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 D--GVEFLWSSEEINNranEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDE-LTAAQIFYPCMQCADIFFLKADICQLGM 215
Cdd:cd00805    83 PpeKAKFVNNSDWLLS---LYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEgISFSEFIYPLLQAYDFVYLDVDLQLGGS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 216 DQRKVNVLAREYctdIKR--KNKPIILSHHMLPGFKEGqeKMSKSDPSSA-IFMEDDEAQVNLKIKQAFCPpnvvdgnPC 292
Cdd:cd00805   160 DQRGNITLGRDL---IRKlgYKKVVGLTTPLLTGLDGG--KMSKSEGNAIwDPVLDSPYDVYQKIRNAFDP-------DV 227

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 293 LEYIKYIVFPWFEMFevvrkeanggnktftnmdELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00805   228 LEFLKLFTFLDYEEI------------------EELEEEHAEGPLPRDAKKALAEELTKL 269
trpS TIGR00233
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ...
 67-360 1.13e-20

tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272975 [Multi-domain]  Cd Length: 327  Bit Score: 91.62  E-value: 1.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSGRMHIAQGIVKTINVNKMVRaGCKVKIWIADWFAQLNNKMGGDLKKIQTvgRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:TIGR00233   6 LTGIQPSGKMHLGHYLGAIQTKWLQQF-GVELFICIADLHAITVKQTDPDALRKAR--EELAADYLAVGLDPEKTFIFLQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEeinnrANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLARE 226
Cdd:TIGR00233  83 SD-----YPEHYELAWLLSCQVTFGELKRMTQFKDKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 227 YCTDIKRKNK-----PIILSHHMLPGFKEGQ-EKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCLEYIK--- 297
Cdd:TIGR00233 158 LAERFNKKFKnffpkPESLISKFFPRLMGLSgKKMSKSDPNSAIFLTDTPKQIKKKIRKA-----ATDGGRVTLFEHrek 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 298 ------YIVFPWFEMFEVVRKEanggnktftnMDELIDDYKTGALHPADVKPALAKAINQILQPIRDHF 360
Cdd:TIGR00233 233 pgvpnlLVIYQYLSFFLIDDDK----------LKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERR 291
TrpS COG0180
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ...
 180-361 9.32e-13

Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439950 [Multi-domain]  Cd Length: 330  Bit Score: 68.54  E-value: 9.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 180 MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LP 246
Cdd:COG0180   114 SAKNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNhrygevfpepEALIPEEGArIP 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 247 GFkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQA--------FCPPNVVDGNPCLEYIKYivfpwfemfevvrkeanggn 318
Cdd:COG0180   189 GL-DGRKKMSKSY-GNTINLLDDPKEIRKKIKSAvtdserlrYDDPGKPEVCNLFTIYSA-------------------- 246

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1002291824 319 ktFTNM---DELIDDYKTGALHPADVKPALAKAINQILQPIRDHFN 361
Cdd:COG0180   247 --FSGKeevEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRA 290
 
Name Accession Description Interval E-value
PTZ00126 PTZ00126
tyrosyl-tRNA synthetase; Provisional
 32-380 0e+00

tyrosyl-tRNA synthetase; Provisional


Pssm-ID: 240282 [Multi-domain]  Cd Length: 383  Bit Score: 652.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00126   35 LSLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSGRMHIAQGILKAINVNKLTKAGCVFVFWVADWFALLNN 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAA 191
Cdd:PTZ00126  115 KMGGDLEKIRKVGEYFIEVWKAAGMDMDNVRFLWASEEINKNPNDYWLRVMDIARSFNITRIKRCSQIMGRSEGDEQPCA 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00126  195 QILYPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKSDPNSAIFMEDSEE 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQ 351
Cdd:PTZ00126  275 DVNRKIKKAYCPPGVIEGNPILAYFKSIVFPAFNSFTVLRKEKNGGDVTYTTYEELEKDYLSGALHPGDLKPALAKYLNL 354

                         330       340
                  ....*....|....*....|....*....
gi 1002291824 352 ILQPIRDHFNNNSEAKILLNTVKKYRVTN 380
Cdd:PTZ00126  355 MLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
PTZ00348 PTZ00348
tyrosyl-tRNA synthetase; Provisional
 32-377 2.19e-154

tyrosyl-tRNA synthetase; Provisional


Pssm-ID: 173541 [Multi-domain]  Cd Length: 682  Bit Score: 450.51  E-value: 2.19e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00348    1 MNTDERYKLLRSVGEECIQESELRNLIEKKPLIRCYDGFEPSGRMHIAQGIFKAVNVNKCTQAGCEFVFWVADWFALMND 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSdELTAA 191
Cdd:PTZ00348   81 KVGGELEKIRIVGRYLIEVWKAAGMDMDKVLFLWSSEEITNHANTYWRTVLDIGRQNTIARIKKCCTIMGKTEG-TLTAA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00348  160 QVLYPLMQCADIFFLKADICQLGLDQRKVNMLAREYCDLIGRKLKPVILSHHMLAGLKQGQAKMSKSDPDSAIFMEDTEE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCP-----PNVV----------DGNPCLEYIKYIVFPWFEMFEVVrkeaNGGnkTFTNMDELIDDYKTGAL 336
Cdd:PTZ00348  240 DVARKIRQAYCPrvkqsASEItddgapvatdDRNPVLDYFQCVVYARPGAVATI----DGT--TYATYEDLEQAFVSDEV 313

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1002291824 337 HPADVKPALAKAINQILQPIRDHFNNNSEAKILLNTVKKYR 377
Cdd:PTZ00348  314 SEEALKSCLIDEVNALLEPVRQHFASNPEAHELLEAVKSYR 354
PRK08560 PRK08560
tyrosyl-tRNA synthetase; Validated
 36-367 1.84e-114

tyrosyl-tRNA synthetase; Validated


Pssm-ID: 236286 [Multi-domain]  Cd Length: 329  Bit Score: 336.45  E-value: 1.84e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  36 DRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIaqGIVKTIN-VNKMVRAGCKVKIWIADWFAQLNNKmg 114
Cdd:PRK08560    3 ERLELITRNTEEVVTEEELRELLESKEEPKAYIGFEPSGKIHL--GHLLTMNkLADLQKAGFKVTVLLADWHAYLNDK-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 115 GDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNraNEYWPLVMDIACKNNVKRIMRCCQIMGRNDsDELTAAQIF 194
Cdd:PRK08560   79 GDLEEIRKVAEYNKKVFEALGLDPDKTEFVLGSEFQLD--KEYWLLVLKLAKNTTLARARRSMTIMGRRM-EEPDVSKLV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 195 YPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKnKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVN 274
Cdd:PRK08560  156 YPLMQVADIFYLDVDIAVGGMDQRKIHMLAREVLPKLGYK-KPVCIHTPLLTGLDGGGIKMSKSKPGSAIFVHDSPEEIR 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 275 LKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:PRK08560  235 RKIKKAYCPPGEVEGNPVLEIAKYHIFPRYDPFVIERPEKYGGDLEYESYEELERDYAEGKLHPMDLKNAVAEYLIEILE 314

                         330
                  ....*....|...
gi 1002291824 355 PIRDHFNNNSEAK 367
Cdd:PRK08560  315 PVREYLEEGPELL 327
tRNA-synt_1b pfam00579
tRNA synthetases class I (W and Y);
59-354 1.85e-71

tRNA synthetases class I (W and Y);


Pssm-ID: 395461 [Multi-domain]  Cd Length: 292  Bit Score: 225.23  E-value: 1.85e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  59 QKKPVPICYDGFEPSGRMHIAqGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYM---IEIWRAAG 135
Cdd:pfam00579   1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaIKAQLACG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 136 MNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGR-NDSDELTAAQIFYPCMQCADIFFLKADICQLG 214
Cdd:pfam00579  80 LDPEKAEIVNNSDWLEHL--ELAWLLRDLGKHFSLNRMLQFKDVKKRlEQGPGISLGEFTYPLLQAYDILLLKADLQPGG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 215 MDQRKVNVLAREYCTDIKRK--NKPIILSHHMLPGFkEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvdGNPC 292
Cdd:pfam00579 158 SDQWGNIELGRDLARRFNKKifKKPVGLTNPLLTGL-DGGKKMSKSAGNSAIFLDDDPESVYKKIQKAYTDPDR--EVRK 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002291824 293 LEYIKYIVFPwfemFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:pfam00579 235 DLKLFTFLSN----EEIEILEAELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
TyrRS_core cd00805
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ...
 67-352 1.40e-35

catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.


Pssm-ID: 173902 [Multi-domain]  Cd Length: 269  Bit Score: 131.19  E-value: 1.40e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSG-RMHIAQGIVkTINVNKMVRAGCKVKIWIADWFAQLNNKMG-------GDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:cd00805     4 YIGFDPTApSLHLGHLVP-LMKLRDFQQAGHEVIVLIGDATAMIGDPSGkseerklLDLELIRENAKYYKKQLKAILDFI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 D--GVEFLWSSEEINNranEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDE-LTAAQIFYPCMQCADIFFLKADICQLGM 215
Cdd:cd00805    83 PpeKAKFVNNSDWLLS---LYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEgISFSEFIYPLLQAYDFVYLDVDLQLGGS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 216 DQRKVNVLAREYctdIKR--KNKPIILSHHMLPGFKEGqeKMSKSDPSSA-IFMEDDEAQVNLKIKQAFCPpnvvdgnPC 292
Cdd:cd00805   160 DQRGNITLGRDL---IRKlgYKKVVGLTTPLLTGLDGG--KMSKSEGNAIwDPVLDSPYDVYQKIRNAFDP-------DV 227

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 293 LEYIKYIVFPWFEMFevvrkeanggnktftnmdELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00805   228 LEFLKLFTFLDYEEI------------------EELEEEHAEGPLPRDAKKALAEELTKL 269
TrpRS_core cd00806
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ...
 67-352 1.30e-23

catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding


Pssm-ID: 173903 [Multi-domain]  Cd Length: 280  Bit Score: 98.81  E-value: 1.30e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMggDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:cd00806     3 LSGIQPSGSLHLGHYLGAFRFWVWLQEAGYELFFFIADLHALTVKQL--DPEELRQNTRENAKDYLACGLDPEKSTIFFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEEInnranEYWPLVMDIACKNNVKRIMRCCQI-MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LA 224
Cdd:cd00806    81 SDVP-----EHYELAWLLSCVVTFGELERMTGFkDKSAQGESVNIGLLTYPVLQAADILLYKACLVPVGIDQ-DPHLeLT 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 225 ReyctDIKRK---------NKPIILSHHM--LPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCL 293
Cdd:cd00806   155 R----DIARRfnklygeifPKPAALLSKGafLPGLQGPSKKMSKSDPNNAIFLTDSPKEIKKKIMKA-----ATDGGRTE 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002291824 294 EYIKY---IVFPWFEMFEVvrkeanggnktFTNMD----ELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00806   226 HRRDGggpGVSNLVEIYSA-----------FFNDDdeelEEIDEYRSGGLGYGECKKLLAEAIQEF 280
trpS TIGR00233
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ...
 67-360 1.13e-20

tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272975 [Multi-domain]  Cd Length: 327  Bit Score: 91.62  E-value: 1.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSGRMHIAQGIVKTINVNKMVRaGCKVKIWIADWFAQLNNKMGGDLKKIQTvgRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:TIGR00233   6 LTGIQPSGKMHLGHYLGAIQTKWLQQF-GVELFICIADLHAITVKQTDPDALRKAR--EELAADYLAVGLDPEKTFIFLQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEeinnrANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLARE 226
Cdd:TIGR00233  83 SD-----YPEHYELAWLLSCQVTFGELKRMTQFKDKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 227 YCTDIKRKNK-----PIILSHHMLPGFKEGQ-EKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCLEYIK--- 297
Cdd:TIGR00233 158 LAERFNKKFKnffpkPESLISKFFPRLMGLSgKKMSKSDPNSAIFLTDTPKQIKKKIRKA-----ATDGGRVTLFEHrek 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 298 ------YIVFPWFEMFEVVRKEanggnktftnMDELIDDYKTGALHPADVKPALAKAINQILQPIRDHF 360
Cdd:TIGR00233 233 pgvpnlLVIYQYLSFFLIDDDK----------LKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERR 291
PTZ00348 PTZ00348
tyrosyl-tRNA synthetase; Provisional
 76-347 1.58e-17

tyrosyl-tRNA synthetase; Provisional


Pssm-ID: 173541 [Multi-domain]  Cd Length: 682  Bit Score: 84.18  E-value: 1.58e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  76 MHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYMIEIWRAAGMNlDGVEFLWSSEEINNRAN 155
Cdd:PTZ00348  388 LDVAEGMIDATKDFIAAHSDGTVTLVLPDWSAVASDEITGEEKDISAALEVNCALLKAYGLP-SEVKIVRENEVILGNPN 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 156 EYWPLVMDIACKNNVKRIMRCCQIMGRNdsdeltAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYctdIKRKN 235
Cdd:PTZ00348  467 DFWVSVIGIARKNLLSHVEELYGGELRN------AGQVIAALMRVATALMLSASHVISTSLDGGINEFAREY---TKGRI 537

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 236 KPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvDGNPCLEYIKYIVFPWfEMFEVVRKEAN 315
Cdd:PTZ00348  538 ECIQALEGRVPALHRPGAAPAVLGADDVLYLDDNDMDIRRKIKKAYSAPNE-EANPVISVAQHLLAQQ-GALSIERGEAN 615

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1002291824 316 GGNKTFTNMDELIDDYKTGALHPADVKPALAK 347
Cdd:PTZ00348  616 GGNVAYNTPEALVADCGSGALHPADLKAAVSQ 647
tyrS TIGR00234
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ...
 36-363 1.44e-15

tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]


Pssm-ID: 272976 [Multi-domain]  Cd Length: 378  Bit Score: 77.44  E-value: 1.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  36 DRFELLRGIGEECIQEDELMNLLQKKPVPI-CYDGFEPSG-RMHIAQgivkTINVNKMVR---AGCKVKIWIADWFAQLN 110
Cdd:TIGR00234   3 NILLLLTKRGLEVQTPEEEKDLLKLLERPLkLYLGFDPTApSLHLGH----LVPLLKLRDfqqAGHEVIVLLGDFTALIG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 111 NKMGGD-LKKI---QTVGR--YMIEIWRAAGMNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGRND 184
Cdd:TIGR00234  79 DPTGKSeVRKIltrEEVQEnaENIKKQIARFLDFEKAKFVYNSEWLLKL--NYTDFIRLLGKIFTVNRMLRRDAFSSRFE 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 185 SDeLTAAQIFYPCMQCADIFFLKADiCQL-GMDQ----RKVNVLAREYctdikRKNKPIILSHHMLPGF------KEGQE 253
Cdd:TIGR00234 157 EN-ISLHEFIYPLLQAYDFVYLNVD-LQLgGSDQwfniRKGRDLAREN-----LPSLQFGLTVPLLTPAdgekmgKSLGG 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 254 KMSKSDPSSA--IFMEDDEAQVNLKIKQAFCPPNV----------------VDGNPCLEYIKYIVFPWF----------- 304
Cdd:TIGR00234 230 AVSLDEGKYDfyQKVINTPDELVKKYLKLFTFLGLeeieqlvelkgpnpreVKENLALEITKYVHGPEAalaaeeiseai 309

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 305 -------EMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPA---LAKAINQILQPIRDHFNNN 363
Cdd:TIGR00234 310 fsgglnpDEVPIFRPEKFGGPITLADLLVLSGLFPSKSEARRDIKNGgvyINGEKVEDLEPIRKELENN 378
PRK12285 PRK12285
tryptophanyl-tRNA synthetase; Reviewed
 67-281 1.30e-14

tryptophanyl-tRNA synthetase; Reviewed


Pssm-ID: 237037 [Multi-domain]  Cd Length: 368  Bit Score: 74.52  E-value: 1.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824  67 YDGFEPSGRMHIAqgivktinvNKMV--------RAGCKVKIWIADWFAQLNNKMggDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:PRK12285   70 YTGFMPSGPMHIG---------HKMVfdelkwhqEFGANVYIPIADDEAYAARGL--SWEETREWAYEYILDLIALGFDP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 DGVEFLWSSEEInnranEYWPLVMDIACK---NNVKrimrccQIMGRNDSDELtaAQIFYPCMQCADIFFLKAD------ 209
Cdd:PRK12285  139 DKTEIYFQSENI-----KVYDLAFELAKKvnfSELK------AIYGFTGETNI--GHIFYPATQAADILHPQLEegpkpt 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 210 ICQLGMDQ----RkvnvLAReyctDIKRK-------NKPIILSHHMLPGFKEGqeKMSKSDPSSAIFMEDDEAQVNLKIK 278
Cdd:PRK12285  206 LVPVGIDQdphiR----LTR----DIAERlhggygfIKPSSTYHKFMPGLTGG--KMSSSKPESAIYLTDDPETVKKKIM 275


                  ...
gi 1002291824 279 QAF 281
Cdd:PRK12285  276 KAL 278
PRK12282 PRK12282
tryptophanyl-tRNA synthetase II; Reviewed
 179-358 5.04e-14

tryptophanyl-tRNA synthetase II; Reviewed


Pssm-ID: 183400 [Multi-domain]  Cd Length: 333  Bit Score: 72.19  E-value: 5.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 179 IMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQ-----------RKVNVLareYCTDIKRKNKPIILSHHMLPG 247
Cdd:PRK12282  114 IAQKGFGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQlpmieqtreivRRFNSL---YGTDVLVEPEALLPEAGRLPG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 248 FkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQAFCPPN--------VVDGNpcleyikyIVFPWFEMFEvvrkeanggnK 319
Cdd:PRK12282  191 L-DGKAKMSKSL-GNAIYLSDDADTIKKKVMSMYTDPNhirvedpgKVEGN--------VVFTYLDAFD----------P 250

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1002291824 320 TFTNMDELIDDYKTGALHPADVKPALAKAINQILQPIRD 358
Cdd:PRK12282  251 DKAEVAELKAHYQRGGLGDVKCKRYLEEVLQELLAPIRE 289
TrpS COG0180
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ...
 180-361 9.32e-13

Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases


Pssm-ID: 439950 [Multi-domain]  Cd Length: 330  Bit Score: 68.54  E-value: 9.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 180 MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LP 246
Cdd:COG0180   114 SAKNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNhrygevfpepEALIPEEGArIP 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 247 GFkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQA--------FCPPNVVDGNPCLEYIKYivfpwfemfevvrkeanggn 318
Cdd:COG0180   189 GL-DGRKKMSKSY-GNTINLLDDPKEIRKKIKSAvtdserlrYDDPGKPEVCNLFTIYSA-------------------- 246

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1002291824 319 ktFTNM---DELIDDYKTGALHPADVKPALAKAINQILQPIRDHFN 361
Cdd:COG0180   247 --FSGKeevEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRA 290
PRK00927 PRK00927
tryptophanyl-tRNA synthetase; Reviewed
 195-358 1.02e-11

tryptophanyl-tRNA synthetase; Reviewed


Pssm-ID: 234866 [Multi-domain]  Cd Length: 333  Bit Score: 65.50  E-value: 1.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 195 YPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LPGFKEGQEKMSKSDPS 261
Cdd:PRK00927  126 YPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNnlygevfpvpEPLIPKVGArVMGLDGPTKKMSKSDPN 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 262 --SAIFMEDDEAQVNLKIKQA-----------FCPPNVVDGNPCLEYIkyivfpwfemfevvrkeanggnKTFTNM--DE 326
Cdd:PRK00927  201 dnNTINLLDDPKTIAKKIKKAvtdserlreirYDLPNKPEVSNLLTIY----------------------SALSGEsiEE 258

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1002291824 327 LIDDYKTGALHPADVKPALAKAINQILQPIRD 358
Cdd:PRK00927  259 LEAEYEAGGKGYGDFKKDLAEAVVEFLAPIRE 290
PLN02486 PLN02486
aminoacyl-tRNA ligase
 169-281 3.14e-05

aminoacyl-tRNA ligase


Pssm-ID: 178104  Cd Length: 383  Bit Score: 45.50  E-value: 3.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 169 NVKRIMRCCQ------IMGRNDSDELtaAQIFYPCMQCA--------DIFFLKADICQL---GMDQRKVNVLAREYCTDI 231
Cdd:PLN02486  166 NMVKIAKCVTlnqvrgIFGFSGEDNI--GKISFPAVQAApsfpssfpHLFGGKDKLRCLipcAIDQDPYFRMTRDVAPRL 243

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1002291824 232 KRKnKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQ-AF 281
Cdd:PLN02486  244 GYY-KPALIESRFFPALQGESGKMSASDPNSAIYVTDTPKEIKNKINKyAF 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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