|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
32-380 |
0e+00 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 652.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00126 35 LSLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSGRMHIAQGILKAINVNKLTKAGCVFVFWVADWFALLNN 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAA 191
Cdd:PTZ00126 115 KMGGDLEKIRKVGEYFIEVWKAAGMDMDNVRFLWASEEINKNPNDYWLRVMDIARSFNITRIKRCSQIMGRSEGDEQPCA 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00126 195 QILYPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKSDPNSAIFMEDSEE 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQ 351
Cdd:PTZ00126 275 DVNRKIKKAYCPPGVIEGNPILAYFKSIVFPAFNSFTVLRKEKNGGDVTYTTYEELEKDYLSGALHPGDLKPALAKYLNL 354
|
330 340
....*....|....*....|....*....
gi 1002291824 352 ILQPIRDHFNNNSEAKILLNTVKKYRVTN 380
Cdd:PTZ00126 355 MLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
59-354 |
1.85e-71 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 225.23 E-value: 1.85e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 59 QKKPVPICYDGFEPSGRMHIAqGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYM---IEIWRAAG 135
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaIKAQLACG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 136 MNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGR-NDSDELTAAQIFYPCMQCADIFFLKADICQLG 214
Cdd:pfam00579 80 LDPEKAEIVNNSDWLEHL--ELAWLLRDLGKHFSLNRMLQFKDVKKRlEQGPGISLGEFTYPLLQAYDILLLKADLQPGG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 215 MDQRKVNVLAREYCTDIKRK--NKPIILSHHMLPGFkEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvdGNPC 292
Cdd:pfam00579 158 SDQWGNIELGRDLARRFNKKifKKPVGLTNPLLTGL-DGGKKMSKSAGNSAIFLDDDPESVYKKIQKAYTDPDR--EVRK 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002291824 293 LEYIKYIVFPwfemFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:pfam00579 235 DLKLFTFLSN----EEIEILEAELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
67-352 |
1.40e-35 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 131.19 E-value: 1.40e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSG-RMHIAQGIVkTINVNKMVRAGCKVKIWIADWFAQLNNKMG-------GDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:cd00805 4 YIGFDPTApSLHLGHLVP-LMKLRDFQQAGHEVIVLIGDATAMIGDPSGkseerklLDLELIRENAKYYKKQLKAILDFI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 D--GVEFLWSSEEINNranEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDE-LTAAQIFYPCMQCADIFFLKADICQLGM 215
Cdd:cd00805 83 PpeKAKFVNNSDWLLS---LYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEgISFSEFIYPLLQAYDFVYLDVDLQLGGS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 216 DQRKVNVLAREYctdIKR--KNKPIILSHHMLPGFKEGqeKMSKSDPSSA-IFMEDDEAQVNLKIKQAFCPpnvvdgnPC 292
Cdd:cd00805 160 DQRGNITLGRDL---IRKlgYKKVVGLTTPLLTGLDGG--KMSKSEGNAIwDPVLDSPYDVYQKIRNAFDP-------DV 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 293 LEYIKYIVFPWFEMFevvrkeanggnktftnmdELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00805 228 LEFLKLFTFLDYEEI------------------EELEEEHAEGPLPRDAKKALAEELTKL 269
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
67-360 |
1.13e-20 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 91.62 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSGRMHIAQGIVKTINVNKMVRaGCKVKIWIADWFAQLNNKMGGDLKKIQTvgRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:TIGR00233 6 LTGIQPSGKMHLGHYLGAIQTKWLQQF-GVELFICIADLHAITVKQTDPDALRKAR--EELAADYLAVGLDPEKTFIFLQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEeinnrANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLARE 226
Cdd:TIGR00233 83 SD-----YPEHYELAWLLSCQVTFGELKRMTQFKDKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 227 YCTDIKRKNK-----PIILSHHMLPGFKEGQ-EKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCLEYIK--- 297
Cdd:TIGR00233 158 LAERFNKKFKnffpkPESLISKFFPRLMGLSgKKMSKSDPNSAIFLTDTPKQIKKKIRKA-----ATDGGRVTLFEHrek 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 298 ------YIVFPWFEMFEVVRKEanggnktftnMDELIDDYKTGALHPADVKPALAKAINQILQPIRDHF 360
Cdd:TIGR00233 233 pgvpnlLVIYQYLSFFLIDDDK----------LKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERR 291
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
180-361 |
9.32e-13 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 68.54 E-value: 9.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 180 MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LP 246
Cdd:COG0180 114 SAKNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNhrygevfpepEALIPEEGArIP 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 247 GFkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQA--------FCPPNVVDGNPCLEYIKYivfpwfemfevvrkeanggn 318
Cdd:COG0180 189 GL-DGRKKMSKSY-GNTINLLDDPKEIRKKIKSAvtdserlrYDDPGKPEVCNLFTIYSA-------------------- 246
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1002291824 319 ktFTNM---DELIDDYKTGALHPADVKPALAKAINQILQPIRDHFN 361
Cdd:COG0180 247 --FSGKeevEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRA 290
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
32-380 |
0e+00 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 652.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00126 35 LSLEERVKLCLSIGEECIQPEELRELLKLKERPICYDGFEPSGRMHIAQGILKAINVNKLTKAGCVFVFWVADWFALLNN 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAA 191
Cdd:PTZ00126 115 KMGGDLEKIRKVGEYFIEVWKAAGMDMDNVRFLWASEEINKNPNDYWLRVMDIARSFNITRIKRCSQIMGRSEGDEQPCA 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00126 195 QILYPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKSDPNSAIFMEDSEE 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQ 351
Cdd:PTZ00126 275 DVNRKIKKAYCPPGVIEGNPILAYFKSIVFPAFNSFTVLRKEKNGGDVTYTTYEELEKDYLSGALHPGDLKPALAKYLNL 354
|
330 340
....*....|....*....|....*....
gi 1002291824 352 ILQPIRDHFNNNSEAKILLNTVKKYRVTN 380
Cdd:PTZ00126 355 MLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
32-377 |
2.19e-154 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 450.51 E-value: 2.19e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 32 MSLQDRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNN 111
Cdd:PTZ00348 1 MNTDERYKLLRSVGEECIQESELRNLIEKKPLIRCYDGFEPSGRMHIAQGIFKAVNVNKCTQAGCEFVFWVADWFALMND 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 112 KMGGDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNRANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSdELTAA 191
Cdd:PTZ00348 81 KVGGELEKIRIVGRYLIEVWKAAGMDMDKVLFLWSSEEITNHANTYWRTVLDIGRQNTIARIKKCCTIMGKTEG-TLTAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 192 QIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKNKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEA 271
Cdd:PTZ00348 160 QVLYPLMQCADIFFLKADICQLGLDQRKVNMLAREYCDLIGRKLKPVILSHHMLAGLKQGQAKMSKSDPDSAIFMEDTEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 272 QVNLKIKQAFCP-----PNVV----------DGNPCLEYIKYIVFPWFEMFEVVrkeaNGGnkTFTNMDELIDDYKTGAL 336
Cdd:PTZ00348 240 DVARKIRQAYCPrvkqsASEItddgapvatdDRNPVLDYFQCVVYARPGAVATI----DGT--TYATYEDLEQAFVSDEV 313
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1002291824 337 HPADVKPALAKAINQILQPIRDHFNNNSEAKILLNTVKKYR 377
Cdd:PTZ00348 314 SEEALKSCLIDEVNALLEPVRQHFASNPEAHELLEAVKSYR 354
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
36-367 |
1.84e-114 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 336.45 E-value: 1.84e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 36 DRFELLRGIGEECIQEDELMNLLQKKPVPICYDGFEPSGRMHIaqGIVKTIN-VNKMVRAGCKVKIWIADWFAQLNNKmg 114
Cdd:PRK08560 3 ERLELITRNTEEVVTEEELRELLESKEEPKAYIGFEPSGKIHL--GHLLTMNkLADLQKAGFKVTVLLADWHAYLNDK-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 115 GDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWSSEEINNraNEYWPLVMDIACKNNVKRIMRCCQIMGRNDsDELTAAQIF 194
Cdd:PRK08560 79 GDLEEIRKVAEYNKKVFEALGLDPDKTEFVLGSEFQLD--KEYWLLVLKLAKNTTLARARRSMTIMGRRM-EEPDVSKLV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 195 YPCMQCADIFFLKADICQLGMDQRKVNVLAREYCTDIKRKnKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVN 274
Cdd:PRK08560 156 YPLMQVADIFYLDVDIAVGGMDQRKIHMLAREVLPKLGYK-KPVCIHTPLLTGLDGGGIKMSKSKPGSAIFVHDSPEEIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 275 LKIKQAFCPPNVVDGNPCLEYIKYIVFPWFEMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:PRK08560 235 RKIKKAYCPPGEVEGNPVLEIAKYHIFPRYDPFVIERPEKYGGDLEYESYEELERDYAEGKLHPMDLKNAVAEYLIEILE 314
|
330
....*....|...
gi 1002291824 355 PIRDHFNNNSEAK 367
Cdd:PRK08560 315 PVREYLEEGPELL 327
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
59-354 |
1.85e-71 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 225.23 E-value: 1.85e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 59 QKKPVPICYDGFEPSGRMHIAqGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYM---IEIWRAAG 135
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQAGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaIKAQLACG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 136 MNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGR-NDSDELTAAQIFYPCMQCADIFFLKADICQLG 214
Cdd:pfam00579 80 LDPEKAEIVNNSDWLEHL--ELAWLLRDLGKHFSLNRMLQFKDVKKRlEQGPGISLGEFTYPLLQAYDILLLKADLQPGG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 215 MDQRKVNVLAREYCTDIKRK--NKPIILSHHMLPGFkEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvdGNPC 292
Cdd:pfam00579 158 SDQWGNIELGRDLARRFNKKifKKPVGLTNPLLTGL-DGGKKMSKSAGNSAIFLDDDPESVYKKIQKAYTDPDR--EVRK 234
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1002291824 293 LEYIKYIVFPwfemFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPALAKAINQILQ 354
Cdd:pfam00579 235 DLKLFTFLSN----EEIEILEAELGKSPYREAEELLAREVTGLVHGGDLKKAAAEAVNKLLQ 292
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
67-352 |
1.40e-35 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 131.19 E-value: 1.40e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSG-RMHIAQGIVkTINVNKMVRAGCKVKIWIADWFAQLNNKMG-------GDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:cd00805 4 YIGFDPTApSLHLGHLVP-LMKLRDFQQAGHEVIVLIGDATAMIGDPSGkseerklLDLELIRENAKYYKKQLKAILDFI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 D--GVEFLWSSEEINNranEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDE-LTAAQIFYPCMQCADIFFLKADICQLGM 215
Cdd:cd00805 83 PpeKAKFVNNSDWLLS---LYTLDFLRLGKHFTVNRMLRRDAVKVRLEEEEgISFSEFIYPLLQAYDFVYLDVDLQLGGS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 216 DQRKVNVLAREYctdIKR--KNKPIILSHHMLPGFKEGqeKMSKSDPSSA-IFMEDDEAQVNLKIKQAFCPpnvvdgnPC 292
Cdd:cd00805 160 DQRGNITLGRDL---IRKlgYKKVVGLTTPLLTGLDGG--KMSKSEGNAIwDPVLDSPYDVYQKIRNAFDP-------DV 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 293 LEYIKYIVFPWFEMFevvrkeanggnktftnmdELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00805 228 LEFLKLFTFLDYEEI------------------EELEEEHAEGPLPRDAKKALAEELTKL 269
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
67-352 |
1.30e-23 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 98.81 E-value: 1.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSGRMHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMggDLKKIQTVGRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:cd00806 3 LSGIQPSGSLHLGHYLGAFRFWVWLQEAGYELFFFIADLHALTVKQL--DPEELRQNTRENAKDYLACGLDPEKSTIFFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEEInnranEYWPLVMDIACKNNVKRIMRCCQI-MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LA 224
Cdd:cd00806 81 SDVP-----EHYELAWLLSCVVTFGELERMTGFkDKSAQGESVNIGLLTYPVLQAADILLYKACLVPVGIDQ-DPHLeLT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 225 ReyctDIKRK---------NKPIILSHHM--LPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCL 293
Cdd:cd00806 155 R----DIARRfnklygeifPKPAALLSKGafLPGLQGPSKKMSKSDPNNAIFLTDSPKEIKKKIMKA-----ATDGGRTE 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1002291824 294 EYIKY---IVFPWFEMFEVvrkeanggnktFTNMD----ELIDDYKTGALHPADVKPALAKAINQI 352
Cdd:cd00806 226 HRRDGggpGVSNLVEIYSA-----------FFNDDdeelEEIDEYRSGGLGYGECKKLLAEAIQEF 280
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
67-360 |
1.13e-20 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 91.62 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSGRMHIAQGIVKTINVNKMVRaGCKVKIWIADWFAQLNNKMGGDLKKIQTvgRYMIEIWRAAGMNLDGVEFLWS 146
Cdd:TIGR00233 6 LTGIQPSGKMHLGHYLGAIQTKWLQQF-GVELFICIADLHAITVKQTDPDALRKAR--EELAADYLAVGLDPEKTFIFLQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 147 SEeinnrANEYWPLVMDIACKNNVKRIMRCCQIMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLARE 226
Cdd:TIGR00233 83 SD-----YPEHYELAWLLSCQVTFGELKRMTQFKDKSQAENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 227 YCTDIKRKNK-----PIILSHHMLPGFKEGQ-EKMSKSDPSSAIFMEDDEAQVNLKIKQAfcppnVVDGNPCLEYIK--- 297
Cdd:TIGR00233 158 LAERFNKKFKnffpkPESLISKFFPRLMGLSgKKMSKSDPNSAIFLTDTPKQIKKKIRKA-----ATDGGRVTLFEHrek 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 298 ------YIVFPWFEMFEVVRKEanggnktftnMDELIDDYKTGALHPADVKPALAKAINQILQPIRDHF 360
Cdd:TIGR00233 233 pgvpnlLVIYQYLSFFLIDDDK----------LKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERR 291
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
76-347 |
1.58e-17 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 84.18 E-value: 1.58e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 76 MHIAQGIVKTINVNKMVRAGCKVKIWIADWFAQLNNKMGGDLKKIQTVGRYMIEIWRAAGMNlDGVEFLWSSEEINNRAN 155
Cdd:PTZ00348 388 LDVAEGMIDATKDFIAAHSDGTVTLVLPDWSAVASDEITGEEKDISAALEVNCALLKAYGLP-SEVKIVRENEVILGNPN 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 156 EYWPLVMDIACKNNVKRIMRCCQIMGRNdsdeltAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYctdIKRKN 235
Cdd:PTZ00348 467 DFWVSVIGIARKNLLSHVEELYGGELRN------AGQVIAALMRVATALMLSASHVISTSLDGGINEFAREY---TKGRI 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 236 KPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQAFCPPNVvDGNPCLEYIKYIVFPWfEMFEVVRKEAN 315
Cdd:PTZ00348 538 ECIQALEGRVPALHRPGAAPAVLGADDVLYLDDNDMDIRRKIKKAYSAPNE-EANPVISVAQHLLAQQ-GALSIERGEAN 615
|
250 260 270
....*....|....*....|....*....|..
gi 1002291824 316 GGNKTFTNMDELIDDYKTGALHPADVKPALAK 347
Cdd:PTZ00348 616 GGNVAYNTPEALVADCGSGALHPADLKAAVSQ 647
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
36-363 |
1.44e-15 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 77.44 E-value: 1.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 36 DRFELLRGIGEECIQEDELMNLLQKKPVPI-CYDGFEPSG-RMHIAQgivkTINVNKMVR---AGCKVKIWIADWFAQLN 110
Cdd:TIGR00234 3 NILLLLTKRGLEVQTPEEEKDLLKLLERPLkLYLGFDPTApSLHLGH----LVPLLKLRDfqqAGHEVIVLLGDFTALIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 111 NKMGGD-LKKI---QTVGR--YMIEIWRAAGMNLDGVEFLWSSEEINNRanEYWPLVMDIACKNNVKRIMRCCQIMGRND 184
Cdd:TIGR00234 79 DPTGKSeVRKIltrEEVQEnaENIKKQIARFLDFEKAKFVYNSEWLLKL--NYTDFIRLLGKIFTVNRMLRRDAFSSRFE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 185 SDeLTAAQIFYPCMQCADIFFLKADiCQL-GMDQ----RKVNVLAREYctdikRKNKPIILSHHMLPGF------KEGQE 253
Cdd:TIGR00234 157 EN-ISLHEFIYPLLQAYDFVYLNVD-LQLgGSDQwfniRKGRDLAREN-----LPSLQFGLTVPLLTPAdgekmgKSLGG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 254 KMSKSDPSSA--IFMEDDEAQVNLKIKQAFCPPNV----------------VDGNPCLEYIKYIVFPWF----------- 304
Cdd:TIGR00234 230 AVSLDEGKYDfyQKVINTPDELVKKYLKLFTFLGLeeieqlvelkgpnpreVKENLALEITKYVHGPEAalaaeeiseai 309
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1002291824 305 -------EMFEVVRKEANGGNKTFTNMDELIDDYKTGALHPADVKPA---LAKAINQILQPIRDHFNNN 363
Cdd:TIGR00234 310 fsgglnpDEVPIFRPEKFGGPITLADLLVLSGLFPSKSEARRDIKNGgvyINGEKVEDLEPIRKELENN 378
|
|
| PRK12285 |
PRK12285 |
tryptophanyl-tRNA synthetase; Reviewed |
67-281 |
1.30e-14 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237037 [Multi-domain] Cd Length: 368 Bit Score: 74.52 E-value: 1.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 67 YDGFEPSGRMHIAqgivktinvNKMV--------RAGCKVKIWIADWFAQLNNKMggDLKKIQTVGRYMIEIWRAAGMNL 138
Cdd:PRK12285 70 YTGFMPSGPMHIG---------HKMVfdelkwhqEFGANVYIPIADDEAYAARGL--SWEETREWAYEYILDLIALGFDP 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 139 DGVEFLWSSEEInnranEYWPLVMDIACK---NNVKrimrccQIMGRNDSDELtaAQIFYPCMQCADIFFLKAD------ 209
Cdd:PRK12285 139 DKTEIYFQSENI-----KVYDLAFELAKKvnfSELK------AIYGFTGETNI--GHIFYPATQAADILHPQLEegpkpt 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 210 ICQLGMDQ----RkvnvLAReyctDIKRK-------NKPIILSHHMLPGFKEGqeKMSKSDPSSAIFMEDDEAQVNLKIK 278
Cdd:PRK12285 206 LVPVGIDQdphiR----LTR----DIAERlhggygfIKPSSTYHKFMPGLTGG--KMSSSKPESAIYLTDDPETVKKKIM 275
|
...
gi 1002291824 279 QAF 281
Cdd:PRK12285 276 KAL 278
|
|
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
179-358 |
5.04e-14 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 72.19 E-value: 5.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 179 IMGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQ-----------RKVNVLareYCTDIKRKNKPIILSHHMLPG 247
Cdd:PRK12282 114 IAQKGFGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQlpmieqtreivRRFNSL---YGTDVLVEPEALLPEAGRLPG 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 248 FkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQAFCPPN--------VVDGNpcleyikyIVFPWFEMFEvvrkeanggnK 319
Cdd:PRK12282 191 L-DGKAKMSKSL-GNAIYLSDDADTIKKKVMSMYTDPNhirvedpgKVEGN--------VVFTYLDAFD----------P 250
|
170 180 190
....*....|....*....|....*....|....*....
gi 1002291824 320 TFTNMDELIDDYKTGALHPADVKPALAKAINQILQPIRD 358
Cdd:PRK12282 251 DKAEVAELKAHYQRGGLGDVKCKRYLEEVLQELLAPIRE 289
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
180-361 |
9.32e-13 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 68.54 E-value: 9.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 180 MGRNDSDELTAAQIFYPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LP 246
Cdd:COG0180 114 SAKNGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNhrygevfpepEALIPEEGArIP 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 247 GFkEGQEKMSKSDpSSAIFMEDDEAQVNLKIKQA--------FCPPNVVDGNPCLEYIKYivfpwfemfevvrkeanggn 318
Cdd:COG0180 189 GL-DGRKKMSKSY-GNTINLLDDPKEIRKKIKSAvtdserlrYDDPGKPEVCNLFTIYSA-------------------- 246
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1002291824 319 ktFTNM---DELIDDYKTGALHPADVKPALAKAINQILQPIRDHFN 361
Cdd:COG0180 247 --FSGKeevEELEAEYRAGGIGYGDLKKALAEAVVEFLAPIRERRA 290
|
|
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
195-358 |
1.02e-11 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 65.50 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 195 YPCMQCADIFFLKADICQLGMDQrKVNV-LAReyctDIKRK-N----------KPIILSHHM-LPGFKEGQEKMSKSDPS 261
Cdd:PRK00927 126 YPVLMAADILLYKADLVPVGEDQ-KQHLeLTR----DIARRfNnlygevfpvpEPLIPKVGArVMGLDGPTKKMSKSDPN 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 262 --SAIFMEDDEAQVNLKIKQA-----------FCPPNVVDGNPCLEYIkyivfpwfemfevvrkeanggnKTFTNM--DE 326
Cdd:PRK00927 201 dnNTINLLDDPKTIAKKIKKAvtdserlreirYDLPNKPEVSNLLTIY----------------------SALSGEsiEE 258
|
170 180 190
....*....|....*....|....*....|..
gi 1002291824 327 LIDDYKTGALHPADVKPALAKAINQILQPIRD 358
Cdd:PRK00927 259 LEAEYEAGGKGYGDFKKDLAEAVVEFLAPIRE 290
|
|
| PLN02486 |
PLN02486 |
aminoacyl-tRNA ligase |
169-281 |
3.14e-05 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178104 Cd Length: 383 Bit Score: 45.50 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1002291824 169 NVKRIMRCCQ------IMGRNDSDELtaAQIFYPCMQCA--------DIFFLKADICQL---GMDQRKVNVLAREYCTDI 231
Cdd:PLN02486 166 NMVKIAKCVTlnqvrgIFGFSGEDNI--GKISFPAVQAApsfpssfpHLFGGKDKLRCLipcAIDQDPYFRMTRDVAPRL 243
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1002291824 232 KRKnKPIILSHHMLPGFKEGQEKMSKSDPSSAIFMEDDEAQVNLKIKQ-AF 281
Cdd:PLN02486 244 GYY-KPALIESRFFPALQGESGKMSASDPNSAIYVTDTPKEIKNKINKyAF 293
|
|
|