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Conserved domains on  [gi|1034558166|ref|XP_016856651|]
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coiled-coil domain-containing protein 18 isoform X1 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
513-1286 2.59e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  513 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKI 592
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  593 VAYSSIAAKNAELEQELMEKNEKIRSLETNINTEhekiclafekakkihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT 672
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESL---------------EAELEELEAELEELESRLEELEEQLETLRSK 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  673 MSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEEtikVRQLDSALEICKEELVLHLNQLEGNKE 752
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE---LQAELEELEEELEELQEELERLEEALE 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  753 KFEKQLKKKSEEVYCLQKELKIKN------HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSK-LE 825
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAaLG 544
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  826 QELQKQRESSAEKLRK----MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMH 901
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  902 LSQLDMIldQTKTELEKKTN---------------------AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKS 960
Cdd:TIGR02168  625 VLVVDDL--DNALELAKKLRpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  961 TLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLdmtiREHRG 1040
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA----EEELA 778
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE 1120
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1121 QYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVRE 1200
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1201 AHLEARmqaeikklsaevesLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEK-------AKLELEEAQDTVSN 1273
Cdd:TIGR02168  939 DNLQER--------------LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERYDF 1004
                          810
                   ....*....|...
gi 1034558166 1274 LHQQVQDRNEVIE 1286
Cdd:TIGR02168 1005 LTAQKEDLTEAKE 1017
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
112-893 2.55e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 2.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  112 EIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQA--------ASVPILEEQIINLEAEVS 183
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyalaNEISRLEQQKQILRERLA 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  184 AQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKL 263
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  264 EKVQAEEEILERNltncekenkrlqercglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKnsEVMAQLTESRQSILKL 343
Cdd:TIGR02168  393 LQIASLNNEIERL------------------EARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEEL 452
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  344 ESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELF-GFKSYLSkyQMSS 422
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsGILGVLS--ELIS 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  423 FSNKEDRCI----GCCEANKLVISELRIKLAI---KEAEIQKLH------ANLTANQLSQSLITCNDSQESSKLSSLETE 489
Cdd:TIGR02168  531 VDEGYEAAIeaalGGRLQAVVVENLNAAKKAIaflKQNELGRVTflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  490 PVK--------LGGHQVAESVKDQNQhtMNKQYeKERQRLVTGIEELRTK--LIQIEAENSDLKVnmahrtsqfqliqee 559
Cdd:TIGR02168  611 DPKlrkalsylLGGVLVVDDLDNALE--LAKKL-RPGYRIVTLDGDLVRPggVITGGSAKTNSSI--------------- 672
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  560 lLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKK 639
Cdd:TIGR02168  673 -LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  640 IHLEQhKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIickqhhlesldrllteskGEMKKENMKKDEALKALQNQV 719
Cdd:TIGR02168  752 LSKEL-TELEAEIEELEERLEEAEEELAEAEAEIEELEAQI------------------EQLKEELKALREALDELRAEL 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  720 SEETIKVRQLDSALEICKEELVLHLNQLegnkEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQM 799
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRL----EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  800 LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRessaEKLRKMEEKCESAaheadlkRQKVIELTGTAR-QVKIEMDQYK 878
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELR----EKLAQLELRLEGL-------EVRIDNLQERLSeEYSLTLEEAE 957
                          810
                   ....*....|....*
gi 1034558166  879 EELSKMEKEIMHLKR 893
Cdd:TIGR02168  958 ALENKIEDDEEEARR 972
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
513-1286 2.59e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  513 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKI 592
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  593 VAYSSIAAKNAELEQELMEKNEKIRSLETNINTEhekiclafekakkihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT 672
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESL---------------EAELEELEAELEELESRLEELEEQLETLRSK 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  673 MSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEEtikVRQLDSALEICKEELVLHLNQLEGNKE 752
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE---LQAELEELEEELEELQEELERLEEALE 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  753 KFEKQLKKKSEEVYCLQKELKIKN------HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSK-LE 825
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAaLG 544
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  826 QELQKQRESSAEKLRK----MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMH 901
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  902 LSQLDMIldQTKTELEKKTN---------------------AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKS 960
Cdd:TIGR02168  625 VLVVDDL--DNALELAKKLRpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  961 TLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLdmtiREHRG 1040
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA----EEELA 778
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE 1120
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1121 QYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVRE 1200
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1201 AHLEARmqaeikklsaevesLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEK-------AKLELEEAQDTVSN 1273
Cdd:TIGR02168  939 DNLQER--------------LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERYDF 1004
                          810
                   ....*....|...
gi 1034558166 1274 LHQQVQDRNEVIE 1286
Cdd:TIGR02168 1005 LTAQKEDLTEAKE 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
112-893 2.55e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 2.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  112 EIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQA--------ASVPILEEQIINLEAEVS 183
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyalaNEISRLEQQKQILRERLA 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  184 AQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKL 263
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  264 EKVQAEEEILERNltncekenkrlqercglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKnsEVMAQLTESRQSILKL 343
Cdd:TIGR02168  393 LQIASLNNEIERL------------------EARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEEL 452
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  344 ESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELF-GFKSYLSkyQMSS 422
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsGILGVLS--ELIS 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  423 FSNKEDRCI----GCCEANKLVISELRIKLAI---KEAEIQKLH------ANLTANQLSQSLITCNDSQESSKLSSLETE 489
Cdd:TIGR02168  531 VDEGYEAAIeaalGGRLQAVVVENLNAAKKAIaflKQNELGRVTflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  490 PVK--------LGGHQVAESVKDQNQhtMNKQYeKERQRLVTGIEELRTK--LIQIEAENSDLKVnmahrtsqfqliqee 559
Cdd:TIGR02168  611 DPKlrkalsylLGGVLVVDDLDNALE--LAKKL-RPGYRIVTLDGDLVRPggVITGGSAKTNSSI--------------- 672
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  560 lLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKK 639
Cdd:TIGR02168  673 -LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  640 IHLEQhKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIickqhhlesldrllteskGEMKKENMKKDEALKALQNQV 719
Cdd:TIGR02168  752 LSKEL-TELEAEIEELEERLEEAEEELAEAEAEIEELEAQI------------------EQLKEELKALREALDELRAEL 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  720 SEETIKVRQLDSALEICKEELVLHLNQLegnkEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQM 799
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRL----EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  800 LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRessaEKLRKMEEKCESAaheadlkRQKVIELTGTAR-QVKIEMDQYK 878
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELR----EKLAQLELRLEGL-------EVRIDNLQERLSeEYSLTLEEAE 957
                          810
                   ....*....|....*
gi 1034558166  879 EELSKMEKEIMHLKR 893
Cdd:TIGR02168  958 ALENKIEDDEEEARR 972
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
915-1205 2.96e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 2.96e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  915 ELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEkyttikdLTAELR 994
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE-------LLAELA 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  995 ECKMEIEDKKQELLEMDQALKERNWELKQraaqvthldmtIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKL 1074
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAE-----------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1075 QNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEA 1154
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034558166 1155 RHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEA 1205
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
558-1102 3.81e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.80  E-value: 3.81e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  558 EELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKA 637
Cdd:PRK03918   203 EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  638 KKihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRL------LTESKGEMKKENMKKDEA 711
Cdd:PRK03918   283 KE--LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKeerleeLKKKLKELEKRLEELEER 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  712 LKALQN--QVSEETIKVRQLDSALEIckEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL 789
Cdd:PRK03918   361 HELYEEakAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC 438
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  790 QHTLQQQQQMLQQETIRN------------GELEDTQTKLEKQVSKLEQELQKQRESSaeKLRKMEEKCESAahEADLKR 857
Cdd:PRK03918   439 PVCGRELTEEHRKELLEEytaelkriekelKEIEEKERKLRKELRELEKVLKKESELI--KLKELAEQLKEL--EEKLKK 514
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  858 QKVIELTGTARqvkiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETEL 937
Cdd:PRK03918   515 YNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEEL 590
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  938 TEALQKREvletELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMD-QALKE 1016
Cdd:PRK03918   591 EERLKELE----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyEELRE 666
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1017 RNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSElELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQNEQEI 1095
Cdd:PRK03918   667 EYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE-KAKKELEKLEKALERVEELREKVKKyKALLKERALSKV 745

                   ....*..
gi 1034558166 1096 SQLKKEI 1102
Cdd:PRK03918   746 GEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
647-1314 1.92e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 1.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  647 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDE-ALKALQNQVSEETIK 725
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKI 225
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  726 VRQLDSALEICKEELVLHLNQLEG----NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQET-----SEQNVILQHTLQQQ 796
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLTEKassarSQANSIQSQLEIIQ 305
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  797 QQMLQQETIRNGELEDtqtkLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQ 876
Cdd:pfam15921  306 EQARNQNSMYMRQLSD----LESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQK 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  877 YKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKL--------QHSTETELTEALQKREVLE 948
Cdd:pfam15921  382 LLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALlkamksecQGQMERQMAAIQGKNESLE 461
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  949 tELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 1028
Cdd:pfam15921  462 -KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEG 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1029 THLDmtirehrgemeqkiiKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQR 1108
Cdd:pfam15921  541 DHLR---------------NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLE 605
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1109 MKEMESVMKEQEQYIatqyKEAIDLGQELRLTREQVQNSHTELAEA----RHQQVQAQREIERLSSELEDMKQLSKEKDA 1184
Cdd:pfam15921  606 LQEFKILKDKKDAKI----RELEARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1185 HGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEM---ISHQENHAKWKISADSQKSSVQQLNEQLEKAK 1261
Cdd:pfam15921  682 NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMkvaMGMQKQITAKRGQIDALQSKIQFLEEAMTNAN 761
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1262 LELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAED 1314
Cdd:pfam15921  762 KEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD 814
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
111-661 4.70e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 4.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  111 QEIKSLREKLNKLRQQnacLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASvpiLEEQIINLEAEVSAQDKVLR 190
Cdd:COG1196    274 LELEELELELEEAQAE---EYELLAELARLEQDIARLEERRRELEERLEELEEELAE---LEEELEELEEELEELEEELE 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  191 EAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEE 270
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  271 EILERNLTNCEKENKRLQERcglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENK 350
Cdd:COG1196    428 EALAELEEEEEEEEEALEEA----AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  351 DEILRDKFSLMNENRELKVRVAAQNERLDlcqqEIESSRVELRSLEKIISQLPLKRElfgfksylskyqmssfsNKEDRC 430
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGV----EAAYEAALEAALAAALQNIVVEDD-----------------EVAAAA 562
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  431 IGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLetepvklgghQVAESVKDQNQHTM 510
Cdd:COG1196    563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL----------GDTLLGRTLVAARL 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  511 nkqyEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEE 590
Cdd:COG1196    633 ----EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034558166  591 KIVAYSSIAAKNAELEQELMEKNEKIRSLEtNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEK 661
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELL-EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PRK12704 PRK12704
phosphodiesterase; Provisional
170-348 2.35e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 48.62  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  170 ILEEQIINLEAEVsaqDKVLREAENKLEQsqkmviEKEQSLQESKEECIKLKvdlleqtkqgkraerqrnealynaEELS 249
Cdd:PRK12704    28 IAEAKIKEAEEEA---KRILEEAKKEAEA------IKKEALLEAKEEIHKLR------------------------NEFE 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  250 KAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLrimavknsEV 329
Cdd:PRK12704    75 KELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL--------ER 146
                          170       180
                   ....*....|....*....|..
gi 1034558166  330 MAQLT--ESRQSIL-KLESELE 348
Cdd:PRK12704   147 ISGLTaeEAKEILLeKVEEEAR 168
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
291-392 5.78e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 41.20  E-value: 5.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  291 CGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDE---ILRDKFSLMNE-NRE 366
Cdd:pfam05911  676 NDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKSQLQESEQLIAELRSELASLKEsnsLAETQLKCMAEsYED 755
                           90       100
                   ....*....|....*....|....*.
gi 1034558166  367 LKVRVAAQNERLDLCQQEIESSRVEL 392
Cdd:pfam05911  756 LETRLTELEAELNELRQKFEALEVEL 781
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
513-1286 2.59e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  513 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKI 592
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  593 VAYSSIAAKNAELEQELMEKNEKIRSLETNINTEhekiclafekakkihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT 672
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESL---------------EAELEELEAELEELESRLEELEEQLETLRSK 387
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  673 MSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEEtikVRQLDSALEICKEELVLHLNQLEGNKE 752
Cdd:TIGR02168  388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE---LQAELEELEEELEELQEELERLEEALE 464
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  753 KFEKQLKKKSEEVYCLQKELKIKN------HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSK-LE 825
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAaLG 544
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  826 QELQKQRESSAEKLRK----MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMH 901
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKaiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  902 LSQLDMIldQTKTELEKKTN---------------------AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKS 960
Cdd:TIGR02168  625 VLVVDDL--DNALELAKKLRpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  961 TLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLdmtiREHRG 1040
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA----EEELA 778
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE 1120
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1121 QYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVRE 1200
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1201 AHLEARmqaeikklsaevesLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEK-------AKLELEEAQDTVSN 1273
Cdd:TIGR02168  939 DNLQER--------------LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERYDF 1004
                          810
                   ....*....|...
gi 1034558166 1274 LHQQVQDRNEVIE 1286
Cdd:TIGR02168 1005 LTAQKEDLTEAKE 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
645-1312 1.49e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 102.44  E-value: 1.49e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  645 HKEMEKQIERLEAQLEKKdQQFKEQEKTMSMLQQDIICKQ--HHLESLDRLlTESKGEMKKENMKKDEALKALQNQVSEE 722
Cdd:TIGR02168  195 LNELERQLKSLERQAEKA-ERYKELKAELRELELALLVLRleELREELEEL-QEELKEAEEELEELTAELQELEEKLEEL 272
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  723 TIKVRQLDSALEICKEELvlhlNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQmlqq 802
Cdd:TIGR02168  273 RLEVSELEEEIEELQKEL----YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE---- 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  803 etirngELEDTQTKLEKQVSKLEqELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 882
Cdd:TIGR02168  345 ------KLEELKEELESLEAELE-ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  883 KMEKEIMHLKRDGENKAMHLSQldMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTL 962
Cdd:TIGR02168  418 RLQQEIEELLKKLEEAELKELQ--AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  963 RQLQELRD-------VLQKA------------QLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDqALKERNWELKQ 1023
Cdd:TIGR02168  496 RLQENLEGfsegvkaLLKNQsglsgilgvlseLISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIA-FLKQNELGRVT 574
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1024 RAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL------NDKLQNAKEQLREKEFIML-------- 1089
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDNALELAKKLRPGYRivtldgdl 654
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1090 ------------QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQ 1157
Cdd:TIGR02168  655 vrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1158 QVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQ-----------------AEIKKLSAEVES 1220
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEeleaqieqlkeelkalrEALDELRAELTL 814
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1221 LKEAYH---MEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKES 1297
Cdd:TIGR02168  815 LNEEAAnlrERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894
                          730
                   ....*....|....*
gi 1034558166 1298 ELTRLQAKISGHEKA 1312
Cdd:TIGR02168  895 ELEELSEELRELESK 909
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
603-1306 5.34e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 5.34e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  603 AELEQELMEKNEKIRSLETNINTEHEKiclAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIIC 682
Cdd:TIGR02168  209 AEKAERYKELKAELRELELALLVLRLE---ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  683 KQHHLESLDRLLTEskgeMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVL---HLNQLEGNKEKFEKQLK 759
Cdd:TIGR02168  286 LQKELYALANEISR----LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEleeKLEELKEELESLEAELE 361
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  760 KKSEEvyclQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGE----LEDTQTKLEKQVSKLEQELQK-QRES 834
Cdd:TIGR02168  362 ELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlerLEDRRERLQQEIEELLKKLEEaELKE 437
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  835 SAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKaMHLSQLDMILDQTKT 914
Cdd:TIGR02168  438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQS 516
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  915 ELEKKTNAVKELEKLQHSTETELTEALQKR-EVLETELQNAHGELKSTLRQLQELR-----------DVLQKAQLSLEEK 982
Cdd:TIGR02168  517 GLSGILGVLSELISVDEGYEAAIEAALGGRlQAVVVENLNAAKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKN 596
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  983 YTTIKDLTAELRECKMEIEDKKQELL-------EMDQALKERNwELKQRAAQVTHLDMTIREH-------------RGEM 1042
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRKALSYLLggvlvvdDLDNALELAK-KLRPGYRIVTLDGDLVRPGgvitggsaktnssILER 675
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1043 EQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMesvmkeqEQY 1122
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-------EER 748
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1123 IATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAH 1202
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1203 LEARM----------QAEIKKLSAEVESLKEayhmEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVS 1272
Cdd:TIGR02168  829 LERRIaaterrledlEEQIEELSEDIESLAA----EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
                          730       740       750
                   ....*....|....*....|....*....|....
gi 1034558166 1273 NLHQQVQDRNEVIEAANEALLTKESELTRLQAKI 1306
Cdd:TIGR02168  905 ELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
557-1306 1.12e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.12e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  557 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNIntehekiclafek 636
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQK------------- 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  637 akKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQ 716
Cdd:TIGR02168  305 --QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  717 NQVSEETIKVRQLDSaLEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQ 796
Cdd:TIGR02168  383 TLRSKVAQLELQIAS-LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEE 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  797 QQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQ 876
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEA 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  877 YKEE---------LSKMEKEIMHLKRDGENKAMHLSqLDMILDQTKTEleKKTNAVKELEKLQHSTETELTEALQKREVL 947
Cdd:TIGR02168  542 ALGGrlqavvvenLNAAKKAIAFLKQNELGRVTFLP-LDSIKGTEIQG--NDREILKNIEGFLGVAKDLVKFDPKLRKAL 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  948 ETELQNAH--GELKSTLRQLQELR----------DVL----------QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQ 1005
Cdd:TIGR02168  619 SYLLGGVLvvDDLDNALELAKKLRpgyrivtldgDLVrpggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEK 698
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1006 ELLEMDQALKERNWELKQRAAQVTHLDMTIREHR---GEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 1082
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA 778
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1083 EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQ 1162
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1163 REIERLSSELEdmkQLSKEKDAHGNHLAEELGASKVREAHLEArMQAEIKKLSAEVESLKEAYhmemishqenhakwkis 1242
Cdd:TIGR02168  859 AEIEELEELIE---ELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRREL----------------- 917
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1243 aDSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTK-ESELTRLQAKI 1306
Cdd:TIGR02168  918 -EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
512-1168 5.59e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 5.59e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  512 KQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 591
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL 384
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  592 IVAYS-------SIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEM----EKQIERLEAQLE 660
Cdd:TIGR02168  385 RSKVAqlelqiaSLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEleelQEELERLEEALE 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  661 KKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLT--ESKGEMKKENMKKDEALKALQNQVSeETIKVrqlDSALEICKE 738
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDSLERLQEnlEGFSEGVKALLKNQSGLSGILGVLS-ELISV---DEGYEAAIE 540
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  739 E-LVLHLNQLEGNKEKFEKQ---LKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGEL---- 810
Cdd:TIGR02168  541 AaLGGRLQAVVVENLNAAKKaiaFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsy 620
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  811 --------EDTQTKLEKQVSK--------LEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 874
Cdd:TIGR02168  621 llggvlvvDDLDNALELAKKLrpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAL 700
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  875 DQYKEELSKMEKEIMHLKRDGEnkamhlsQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNA 954
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELE-------ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  955 HGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQ---ALKERNWELKQRAAQVTHL 1031
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERriaATERRLEDLEEQIEELSED 853
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1032 DMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 1111
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034558166 1112 MESVMKEQEQYIATQYKEAIDLGQELRLTREqvqnshTELAEARHQQVQAQREIERL 1168
Cdd:TIGR02168  934 LEVRIDNLQERLSEEYSLTLEEAEALENKIE------DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
112-893 2.55e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 2.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  112 EIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQA--------ASVPILEEQIINLEAEVS 183
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyalaNEISRLEQQKQILRERLA 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  184 AQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKL 263
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  264 EKVQAEEEILERNltncekenkrlqercglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKnsEVMAQLTESRQSILKL 343
Cdd:TIGR02168  393 LQIASLNNEIERL------------------EARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEEL 452
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  344 ESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELF-GFKSYLSkyQMSS 422
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsGILGVLS--ELIS 530
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  423 FSNKEDRCI----GCCEANKLVISELRIKLAI---KEAEIQKLH------ANLTANQLSQSLITCNDSQESSKLSSLETE 489
Cdd:TIGR02168  531 VDEGYEAAIeaalGGRLQAVVVENLNAAKKAIaflKQNELGRVTflpldsIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  490 PVK--------LGGHQVAESVKDQNQhtMNKQYeKERQRLVTGIEELRTK--LIQIEAENSDLKVnmahrtsqfqliqee 559
Cdd:TIGR02168  611 DPKlrkalsylLGGVLVVDDLDNALE--LAKKL-RPGYRIVTLDGDLVRPggVITGGSAKTNSSI--------------- 672
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  560 lLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKK 639
Cdd:TIGR02168  673 -LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  640 IHLEQhKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIickqhhlesldrllteskGEMKKENMKKDEALKALQNQV 719
Cdd:TIGR02168  752 LSKEL-TELEAEIEELEERLEEAEEELAEAEAEIEELEAQI------------------EQLKEELKALREALDELRAEL 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  720 SEETIKVRQLDSALEICKEELVLHLNQLegnkEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQM 799
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRL----EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  800 LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRessaEKLRKMEEKCESAaheadlkRQKVIELTGTAR-QVKIEMDQYK 878
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELR----EKLAQLELRLEGL-------EVRIDNLQERLSeEYSLTLEEAE 957
                          810
                   ....*....|....*
gi 1034558166  879 EELSKMEKEIMHLKR 893
Cdd:TIGR02168  958 ALENKIEDDEEEARR 972
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
915-1205 2.96e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 2.96e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  915 ELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEkyttikdLTAELR 994
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE-------LLAELA 298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  995 ECKMEIEDKKQELLEMDQALKERNWELKQraaqvthldmtIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKL 1074
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAE-----------LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1075 QNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEA 1154
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034558166 1155 RHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEA 1205
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
809-1184 1.67e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 1.67e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  809 ELEDTQTKLEKqVSKLEQELQKQRESsaeklrkmeekcesaaheadLKRQKvieltGTARQVKiemdQYKEELSKMEKEI 888
Cdd:COG1196    180 KLEATEENLER-LEDILGELERQLEP--------------------LERQA-----EKAERYR----ELKEELKELEAEL 229
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  889 MHLKRDgenkamhlsQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQEL 968
Cdd:COG1196    230 LLLKLR---------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  969 RDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQvthldmtirehRGEMEQKIIK 1048
Cdd:COG1196    301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-----------LAEAEEALLE 369
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1049 LEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYK 1128
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166 1129 EAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDA 1184
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1012-1319 1.79e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 1.79e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1012 QALKErnwELKQRAAQVTHLDM-TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQ 1090
Cdd:COG1196    216 RELKE---ELKELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1091 NEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSS 1170
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1171 ELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLsAEVESLKEAYHMEMISHQENHAKWKISADSQKSSV 1250
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL-ERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1251 QQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAEDIKFLP 1319
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
245-1119 9.16e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 9.16e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  245 AEELSKAFQQYKK--KVAEKLEKVQAEEEILERnltncekenkrlqercGLYKSELEILKEKLRQLKEENNNGKEKLRIM 322
Cdd:TIGR02168  195 LNELERQLKSLERqaEKAERYKELKAELRELEL----------------ALLVLRLEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  323 AVKNSEVMAQLTESRQSILKLESELENKDEILrdkFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKiisql 402
Cdd:TIGR02168  259 TAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEAQLEELES----- 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  403 plKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSK 482
Cdd:TIGR02168  331 --KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  483 LSSLEtepvklggHQVAESVKDQNQHTMNKQyEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLe 562
Cdd:TIGR02168  409 LERLE--------DRRERLQQEIEELLKKLE-EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD- 478
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  563 kasnssKLESEMTKKCSQLLTLEKQLEEkivaYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEkiclaFEKAKKIHL 642
Cdd:TIGR02168  479 ------AAERELAQLQARLDSLERLQEN----LEGFSEGVKALLKNQSGLSGILGVLSELISVDEG-----YEAAIEAAL 543
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  643 EQHKEMeKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMK--KENMKKDEALKALQNQVS 720
Cdd:TIGR02168  544 GGRLQA-VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGvaKDLVKFDPKLRKALSYLL 622
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  721 EETIKVRQLDSALEICKE------------ELVL------------HLNQLEGNKE--KFEKQLKKKSEEVYCLQKELKI 774
Cdd:TIGR02168  623 GGVLVVDDLDNALELAKKlrpgyrivtldgDLVRpggvitggsaktNSSILERRREieELEEKIEELEEKIAELEKALAE 702
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  775 KNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESsAEKLRKMEEKCESAAHEAD 854
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE-IEELEERLEEAEEELAEAE 781
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  855 LKRQkviELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE 934
Cdd:TIGR02168  782 AEIE---ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  935 TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQAL 1014
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1015 KernwELKQRAAQVTHLDMtirehrGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE----KEFImlq 1090
Cdd:TIGR02168  939 D----NLQERLSEEYSLTL------EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEElkerYDFL--- 1005
                          890       900
                   ....*....|....*....|....*....
gi 1034558166 1091 nEQEISQLKKEIERTQQRMKEMESVMKEQ 1119
Cdd:TIGR02168 1006 -TAQKEDLTEAKETLEEAIEEIDREARER 1033
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
558-1102 3.81e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.80  E-value: 3.81e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  558 EELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKA 637
Cdd:PRK03918   203 EEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  638 KKihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRL------LTESKGEMKKENMKKDEA 711
Cdd:PRK03918   283 KE--LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKeerleeLKKKLKELEKRLEELEER 360
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  712 LKALQN--QVSEETIKVRQLDSALEIckEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL 789
Cdd:PRK03918   361 HELYEEakAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC 438
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  790 QHTLQQQQQMLQQETIRN------------GELEDTQTKLEKQVSKLEQELQKQRESSaeKLRKMEEKCESAahEADLKR 857
Cdd:PRK03918   439 PVCGRELTEEHRKELLEEytaelkriekelKEIEEKERKLRKELRELEKVLKKESELI--KLKELAEQLKEL--EEKLKK 514
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  858 QKVIELTGTARqvkiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETEL 937
Cdd:PRK03918   515 YNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEEL 590
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  938 TEALQKREvletELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMD-QALKE 1016
Cdd:PRK03918   591 EERLKELE----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyEELRE 666
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1017 RNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSElELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQNEQEI 1095
Cdd:PRK03918   667 EYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE-KAKKELEKLEKALERVEELREKVKKyKALLKERALSKV 745

                   ....*..
gi 1034558166 1096 SQLKKEI 1102
Cdd:PRK03918   746 GEIASEI 752
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
559-1311 8.02e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 8.02e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  559 ELLEKASNSSKLESEMTKKCSQLLTLEKQLEEkivAYSSIAAKNAELEQELMEKNEKIRSLEtnINTEHEKICL-AFEKA 637
Cdd:TIGR02169  157 KIIDEIAGVAEFDRKKEKALEELEEVEENIER---LDLIIDEKRQQLERLRREREKAERYQA--LLKEKREYEGyELLKE 231
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  638 KKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMsmlqqdiickqhhlESLDRLLTESKGEMKKenmKKDEALKALQN 717
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRL--------------EEIEQLLEELNKKIKD---LGEEEQLRVKE 294
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  718 QVSEETIKVRQLDSALEICKEELvlhlNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQ 797
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKEREL----EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  798 QMLQQETIRNGELEDTQTKLEKQVSKLEQELQkqrESSAEKLRKMEEKCESAAHEADLkRQKVIELTGTARQVKIEMDQY 877
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREIN---ELKRELDRLQEELQRLSEELADL-NAAIAGIEAKINELEEEKEDK 446
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  878 KEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGe 957
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHG- 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  958 lksTLRQLQELRDVLQKA------------------------QLSLEEK--------YTTIKDLTAELRECKME-IEDKK 1004
Cdd:TIGR02169  526 ---TVAQLGSVGERYATAievaagnrlnnvvveddavakeaiELLKRRKagratflpLNKMRDERRDLSILSEDgVIGFA 602
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1005 QELLEMDQALKERNWELKQRAAQVTHLDmTIREHRGEMeqKIIKLEGTL-EKSELELKECNKQIESLNDKLQNAKE--QL 1081
Cdd:TIGR02169  603 VDLVEFDPKYEPAFKYVFGDTLVVEDIE-AARRLMGKY--RMVTLEGELfEKSGAMTGGSRAPRGGILFSRSEPAElqRL 679
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1082 REKEFIMlqnEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNShtelaearhqqvqa 1161
Cdd:TIGR02169  680 RERLEGL---KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL-------------- 742
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1162 QREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARM-QAEIKKLSAEVESLKEaYHMEmISHQENHAKWK 1240
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLsHSRIPEIQAELSKLEE-EVSR-IEARLREIEQK 820
                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166 1241 ISADSQK-----SSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEK 1311
Cdd:TIGR02169  821 LNRLTLEkeyleKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
558-1185 1.31e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 72.77  E-value: 1.31e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  558 EELLEKASNSS-KLESEMTKKCSQLLTLEKQLEEKIVAysSIAAKNAELEQELMEKNEKIRSLETNINTEHEkiclAFEK 636
Cdd:PRK02224   165 EEYRERASDARlGVERVLSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARE----TRDE 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  637 AKKIhLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKkDEALKALQ 716
Cdd:PRK02224   239 ADEV-LEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDAD-AEAVEARR 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  717 NQVSEETIKVRQldsALEICKEELVLHLNQLEGNKEK---FEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTL 793
Cdd:PRK02224   317 EELEDRDEELRD---RLEECRVAAQAHNEEAESLREDaddLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI 393
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  794 QQQQQMLQQETIRNGELED-------TQTKLEKQVSKLEQELQKQRESSAEKLRKMEE-KC-------ESAAH--EADLK 856
Cdd:PRK02224   394 EELRERFGDAPVDLGNAEDfleelreERDELREREAELEATLRTARERVEEAEALLEAgKCpecgqpvEGSPHveTIEED 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  857 RQKVIELTGtarqvkiEMDQYKEELSKMEKEIMHLKRdgenkamhlsqldmiLDQTKTELEKKTNAVKELEKLQHSTETE 936
Cdd:PRK02224   474 RERVEELEA-------ELEDLEEEVEEVEERLERAED---------------LVEAEDRIERLEERREDLEELIAERRET 531
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  937 LTEalqKREVLEtELQNAHGELKStlrQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIE--DKKQELLEMDQAL 1014
Cdd:PRK02224   532 IEE---KRERAE-ELRERAAELEA---EAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIEslERIRTLLAAIADA 604
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1015 KERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSelelkecnkQIESLNDKLQNAKEQLREKEFIMLQNEQE 1094
Cdd:PRK02224   605 EDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA---------RIEEAREDKERAEEYLEQVEEKLDELREE 675
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1095 ISQLKKEIERTQQRMKEMESVMKEQE------QYIATQYKEAidlgqelrltrEQVQNSHTEL-AEARhqqvqaQREIER 1167
Cdd:PRK02224   676 RDDLQAEIGAVENELEELEELRERREalenrvEALEALYDEA-----------EELESMYGDLrAELR------QRNVET 738
                          650
                   ....*....|....*...
gi 1034558166 1168 LSSELEDMKQLSKEKDAH 1185
Cdd:PRK02224   739 LERMLNETFDLVYQNDAY 756
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
512-1119 1.67e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 1.67e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  512 KQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 591
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  592 IVAYSSIAAKNAELEQELMEKNEKIRSLEtninTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEK 671
Cdd:COG1196    322 EEELAELEEELEELEEELEELEEELEEAE----EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  672 TMSMLQQDIICKQHHLESLDRLLTEsKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNK 751
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEE-LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  752 EKFEKQLKKKSEEVycLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQ 831
Cdd:COG1196    477 AALAELLEELAEAA--ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  832 RESSAEKLrkmeekcesAAHEADLKRQKVIELTGTARQVKiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQ 911
Cdd:COG1196    555 DDEVAAAA---------IEYLKAAKAGRATFLPLDKIRAR-AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG 624
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  912 TKTELEKKTNAVKELEKLqhstETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 991
Cdd:COG1196    625 RTLVAARLEAALRRAVTL----AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  992 ELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL- 1070
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALg 780
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1071 --NdklQNAKEQLRE----KEFIMLQNEqeisQLKKEIERTQQRMKEMESVMKEQ 1119
Cdd:COG1196    781 pvN---LLAIEEYEEleerYDFLSEQRE----DLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
712-1306 2.90e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 2.90e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  712 LKALQNQvSEETIKVRQLDSALEICK-EELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQnvilq 790
Cdd:COG1196    202 LEPLERQ-AEKAERYRELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE----- 275
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  791 htlqqqqqmlqQETIRNgELEDTQTKLEKQVSKLEQeLQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV 870
Cdd:COG1196    276 -----------LEELEL-ELEEAQAEEYELLAELAR-LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  871 KIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETE 950
Cdd:COG1196    343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  951 LQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECK---MEIEDKKQELLEMDQALKERNWELKQRAAQ 1027
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLeeaALLEAALAELLEELAEAAARLLLLLEAEAD 502
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1028 VTHLDMTIREHRGEMEQKIIKLEGTL----EKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIE 1103
Cdd:COG1196    503 YEGFLEGVKAALLLAGLRGLAGAVAVligvEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKI 582
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1104 RTQQRMKEMESVMKEQEQYIATQYkEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKD 1183
Cdd:COG1196    583 RARAALAAALARGAIGAAVDLVAS-DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1184 AHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQEnhakwKISADSQKSSVQQLNEQLEKAKLE 1263
Cdd:COG1196    662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA-----EEERLEEELEEEALEEQLEAEREE 736
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1034558166 1264 LEEAQDTVSNLHQQVQDRNEVIEAANEALltkESELTRLQAKI 1306
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPDLEEL---ERELERLEREI 776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
552-1115 3.02e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 3.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  552 QFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEkivayssIAAKNAELEQELMEKNEKIRSLETNINTEHEKIc 631
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEE-------LRLELEELELELEEAQAEEYELLAELARLEQDI- 304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  632 lAFEKAKKIHLEQHK-EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDE 710
Cdd:COG1196    305 -ARLEERRRELEERLeELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  711 ALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 790
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  791 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV 870
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA 543
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  871 KIEMDQYK--EELSKMEKEIMHLKRDGENKAMHLSQLDM------ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 942
Cdd:COG1196    544 LAAALQNIvvEDDEVAAAAIEYLKAAKAGRATFLPLDKIraraalAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  943 KREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELK 1022
Cdd:COG1196    624 GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1023 QRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKEcnkqieslndklqnAKEQLREKEFIMLQNEQEISQLKKEI 1102
Cdd:COG1196    704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE--------------EEELLEEEALEELPEPPDLEELEREL 769
                          570
                   ....*....|...
gi 1034558166 1103 ERTQQRMKEMESV 1115
Cdd:COG1196    770 ERLEREIEALGPV 782
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
512-1277 5.96e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.87  E-value: 5.96e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  512 KQYEKERQRLVTGIEELRTKLIQIEAENSDLkvnMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 591
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKA---ERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  592 IVAYSSIAAKNAELEQELMEKNEKIRSLetninTEHEKICLafekAKKIHleqhkEMEKQIERLEAQLEKKDQQFKEQEK 671
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLRV----KEKIG-----ELEAEIASLERSIAEKERELEDAEE 322
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  672 TMSMLQQDIICKQHHLESLDRLLTESKGE---MKKENMKKDEALKALQNQVSEETIK---VRQLDSALEICKEELVLHLN 745
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRrdkLTEEYAELKEELEDLRAELEEVDKEfaeTRDELKDYREKLEKLKREIN 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  746 QLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSL----------------QETSEQNVILQHTLQQQQQMLQQETIRngE 809
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKIneleeekedkaleikkQEWKLEQLAADLSKYEQELYDLKEEYD--R 480
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  810 LEDTQTKLEKQVSKLEQELQKQRESSAE--------------------KLRKMEEK----CESAAH--------EADLKR 857
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERVRGgraveevlkasiqgvhgtvaQLGSVGERyataIEVAAGnrlnnvvvEDDAVA 560
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  858 QKVIELtgtARQVKI---------EMDQYKEELSKMEKEIMH-------------------------LKRDGENKAMHLS 903
Cdd:TIGR02169  561 KEAIEL---LKRRKAgratflplnKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgdtlVVEDIEAARRLMG 637
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  904 QLDM-------------ILDQTKTELEKKTNAVKELEKLQH------STETELTEALQKREVLETELQNAHGELKSTLRQ 964
Cdd:TIGR02169  638 KYRMvtlegelfeksgaMTGGSRAPRGGILFSRSEPAELQRlrerleGLKRELSSLQSELRRIENRLDELSQELSDASRK 717
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  965 LQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDM--------TIR 1036
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlshsripEIQ 797
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1037 EHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 1116
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1117 KEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELedmKQLSKEKDAHGNHLAEELGAS 1196
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL---SEIEDPKGEDEEIPEEELSLE 954
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1197 KVreahlearmQAEIKKLSAEVESLKEayhMEMISHQEnhakWKISADSQKSsvqqLNEQLEKAKLELEEAQDTVSNLHQ 1276
Cdd:TIGR02169  955 DV---------QAELQRVEEEIRALEP---VNMLAIQE----YEEVLKRLDE----LKEKRAKLEEERKAILERIEEYEK 1014

                   .
gi 1034558166 1277 Q 1277
Cdd:TIGR02169 1015 K 1015
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
647-1221 3.19e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 3.19e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  647 EMEKQIERLEAQLEK--KDQQFKEQEKtmsmlQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEA---LKALQNQVSE 721
Cdd:COG1196    197 ELERQLEPLERQAEKaeRYRELKEELK-----ELEAELLLLKLRELEAELEELEAELEELEAELEELeaeLAELEAELEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  722 ETIKVRQLDSALEICKEELVLHLNQLEgnkeKFEKQLKKKSEEvyclqkelkIKNHSLQETSEQNVILQHTLQQQQQMLQ 801
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELA----RLEQDIARLEER---------RRELEERLEELEEELAELEEELEELEEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  802 QETIRNgELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKcESAAHEADLKRQKVIELTGTARQVKIEMDQYKEEL 881
Cdd:COG1196    339 LEELEE-ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-EELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  882 SKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKST 961
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  962 LRQLQELRDVLQKAQ-LSLEEKYTTIKDLTAELRECKMEIEDKKQELL----------EMDQALKERNWELKQRAAQVTH 1030
Cdd:COG1196    497 LEAEADYEGFLEGVKaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALaaalqnivveDDEVAAAAIEYLKAAKAGRATF 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1031 LDMT---------IREHRGEMEQKIIKLEGTLEKSELELKECNKQIE---SLNDKLQNAKEQLREKEFIMLQNEQEISQL 1098
Cdd:COG1196    577 LPLDkiraraalaAALARGAIGAAVDLVASDLREADARYYVLGDTLLgrtLVAARLEAALRRAVTLAGRLREVTLEGEGG 656
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1099 KKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQL 1178
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1034558166 1179 SKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESL 1221
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
579-1224 4.92e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 4.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  579 SQLLTLEKQleekivaySSIAAKNAELEQELMEKNE-----KIRSLETNINTEHEKIcLAFEKAKKIHLEQHKEMEKQIE 653
Cdd:COG1196    200 RQLEPLERQ--------AEKAERYRELKEELKELEAellllKLRELEAELEELEAEL-EELEAELEELEAELAELEAELE 270
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  654 RLEAQLEKKDQQFKEQEKTMSMLQQDIIckqhHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSAL 733
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELA----RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  734 EICKEELVLHLNQLEGNKEKFEKQLKKKSEEvycLQKELKIKNHSLQETSEQNVILQHTLQQQQqmlqqetirngELEDT 813
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEA---EEELEELAEELLEALRAAAELAAQLEELEE-----------AEEAL 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  814 QTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKR 893
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  894 DGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALqkREVLETELQNAHGElksTLRQLQELRDVLQ 973
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL--EAALAAALQNIVVE---DDEVAAAAIEYLK 567
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  974 KAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERnwELKQRAAQVTHLDMTIREHRGEMEQKIIK-LEGT 1052
Cdd:COG1196    568 AAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA--DARYYVLGDTLLGRTLVAARLEAALRRAVtLAGR 645
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1053 LEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAID 1132
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1133 LGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELE-DMKQLSKEKDAHG--NHLA-EELGASKVREAHLEarmq 1208
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELErELERLEREIEALGpvNLLAiEEYEELEERYDFLS---- 801
                          650
                   ....*....|....*.
gi 1034558166 1209 AEIKKLSAEVESLKEA 1224
Cdd:COG1196    802 EQREDLEEARETLEEA 817
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1090-1325 6.13e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.94  E-value: 6.13e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1090 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLS 1169
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1170 SELEDMKQLSkEKDAHGNHLAEELGASKVREAhleARMQAEIKKLSAEVESLKEayhmEMISHQENHAKWKISADSQKSS 1249
Cdd:COG4942    104 EELAELLRAL-YRLGRQPPLALLLSPEDFLDA---VRRLQYLKYLAPARREQAE----ELRADLAELAALRAELEAERAE 175
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166 1250 VQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAEDIKFLPAPFTSP 1325
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
109-700 1.72e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.23  E-value: 1.72e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  109 VDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSML-ESAQQQAASVPILEEQIINLEAEVSAQDK 187
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELkEELESLEAELEELEAELEELESRLEELEE 379
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  188 VLREAENKL--EQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKafqqykkkVAEKLEK 265
Cdd:TIGR02168  380 QLETLRSKVaqLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE--------LEEELEE 451
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  266 VQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLK--EENNNGKEKLRIMAVKNSEVMAQLTESRQSILKL 343
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlQENLEGFSEGVKALLKNQSGLSGILGVLSELISV 531
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  344 ESELE----------------NKDEILRDKFSLMNENRELKVRVAAQNerlDLCQQEIESSRVE--------LRSLEKII 399
Cdd:TIGR02168  532 DEGYEaaieaalggrlqavvvENLNAAKKAIAFLKQNELGRVTFLPLD---SIKGTEIQGNDREilkniegfLGVAKDLV 608
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  400 SQLPLKRELFGF------------------KSYLSKYQ--------------MSSFSNKEDRCIGCCEANklvISELRIK 447
Cdd:TIGR02168  609 KFDPKLRKALSYllggvlvvddldnalelaKKLRPGYRivtldgdlvrpggvITGGSAKTNSSILERRRE---IEELEEK 685
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  448 LAIKEAEIQKLHANLTANQLSQSLITCNDSQ-------ESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQR 520
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQlrkeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  521 LVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAA 600
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  601 KNAELEQELMEKNEKIRSLETNINTEHEKIclafekakKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI 680
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESEL--------EALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917
                          650       660
                   ....*....|....*....|
gi 1034558166  681 ICKQHHLESLDRLLTESKGE 700
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVR 937
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
647-1314 1.92e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 1.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  647 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDE-ALKALQNQVSEETIK 725
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKI 225
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  726 VRQLDSALEICKEELVLHLNQLEG----NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQET-----SEQNVILQHTLQQQ 796
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLTEKassarSQANSIQSQLEIIQ 305
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  797 QQMLQQETIRNGELEDtqtkLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQ 876
Cdd:pfam15921  306 EQARNQNSMYMRQLSD----LESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQK 381
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  877 YKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKL--------QHSTETELTEALQKREVLE 948
Cdd:pfam15921  382 LLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALlkamksecQGQMERQMAAIQGKNESLE 461
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  949 tELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 1028
Cdd:pfam15921  462 -KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEG 540
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1029 THLDmtirehrgemeqkiiKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQR 1108
Cdd:pfam15921  541 DHLR---------------NVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLE 605
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1109 MKEMESVMKEQEQYIatqyKEAIDLGQELRLTREQVQNSHTELAEA----RHQQVQAQREIERLSSELEDMKQLSKEKDA 1184
Cdd:pfam15921  606 LQEFKILKDKKDAKI----RELEARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1185 HGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEM---ISHQENHAKWKISADSQKSSVQQLNEQLEKAK 1261
Cdd:pfam15921  682 NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMkvaMGMQKQITAKRGQIDALQSKIQFLEEAMTNAN 761
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1262 LELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAED 1314
Cdd:pfam15921  762 KEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
810-1314 4.32e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 4.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  810 LEDTQTKLEKQVSKLEQELqKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV---KIEMDQYKEELSKMEK 886
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFI-KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEK 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  887 EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLEtELQNAHGELKSTLRQLQ 966
Cdd:PRK03918   246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLD-ELREIEKRLSRLEEEIN 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  967 ELRDVLQKAQlSLEEKYTTIKDLTAELRECKMEIEdKKQELLEMDQALKERNWELKQRAAQVTHLDM-----TIREHRGE 1041
Cdd:PRK03918   325 GIEERIKELE-EKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTPEKLekeleELEKAKEE 402
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1042 MEQKIIKLE---GTLEKSELELKECNKQIESLNDKLQNAKEQLRE--KEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 1116
Cdd:PRK03918   403 IEEEISKITariGELKKEIKELKKAIEELKKAKGKCPVCGRELTEehRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1117 KEQEQYIATQ-----YKEAIDLGQELR-----LTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHG 1186
Cdd:PRK03918   483 RELEKVLKKEselikLKELAEQLKELEeklkkYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELE 562
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1187 NHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYhmemishqenhaKWKISADSQKSSVQQLNEQLEKAKLELEE 1266
Cdd:PRK03918   563 KKLDELEEELAELLKELEELGFESVEELEERLKELEPFY------------NEYLELKDAEKELEREEKELKKLEEELDK 630
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1267 AQDTVSNLHQQVQDRNEVIEAAN------------EALLTKESELTRLQAKISGHEKAED 1314
Cdd:PRK03918   631 AFEELAETEKRLEELRKELEELEkkyseeeyeelrEEYLELSRELAGLRAELEELEKRRE 690
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
634-1223 5.25e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 5.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  634 FEKAKKIHLEQHKEMEKQIERLEAQLEKK---DQQFKEQEKTMSMLQQDIICKQHHLESLdrlltESKGEMKKENMKKDE 710
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIERLEKFIKRTeniEELIKEKEKELEEVLREINEISSELPEL-----REELEKLEKEVKELE 234
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  711 ALKALQNQVSEETIKVRQLDSALEICKEELvlhlnqlegnkEKFEKQLKKKSEEVYCLQKELKiknhSLQETSEQNVILQ 790
Cdd:PRK03918   235 ELKEEIEELEKELESLEGSKRKLEEKIREL-----------EERIEELKKEIEELEEKVKELK----ELKEKAEEYIKLS 299
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  791 HTLQQQQQMLQqetirngELEDTQTKLEKQVSKLEQELQKqRESSAEKLRKMEEKCESAAHEADLKRQKViELTGTARQV 870
Cdd:PRK03918   300 EFYEEYLDELR-------EIEKRLSRLEEEINGIEERIKE-LEEKEERLEELKKKLKELEKRLEELEERH-ELYEEAKAK 370
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  871 KIEMDQYKEELS-----KMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTET---ELTEALQ 942
Cdd:PRK03918   371 KEELERLKKRLTgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgrELTEEHR 450
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  943 KREVLE--TELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKdltaeLRECKMEIEDKKQELLEMDQALKERNWE 1020
Cdd:PRK03918   451 KELLEEytAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIK-----LKELAEQLKELEEKLKKYNLEELEKKAE 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1021 LKQraaqvthldmTIREHRGEMEQKIIKLEGTLEKSEL---ELKECNKQIESLNDKLQNAKEQLREKEFimlqneqeisq 1097
Cdd:PRK03918   526 EYE----------KLKEKLIKLKGEIKSLKKELEKLEElkkKLAELEKKLDELEEELAELLKELEELGF----------- 584
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1098 lkKEIERTQQRMKEMESVMKEqeqyiatqYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQ 1177
Cdd:PRK03918   585 --ESVEELEERLKELEPFYNE--------YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK 654
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1178 LSKEKDahgnhlaeelgASKVREAHLEARMqaEIKKLSAEVESLKE 1223
Cdd:PRK03918   655 KYSEEE-----------YEELREEYLELSR--ELAGLRAELEELEK 687
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
810-1122 6.37e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 6.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  810 LEDTQTKLEKQVSKLEQELQKqressAEKLRKMEEKCESAAHEAdlkrqkvieLTGTARQVKIEMDQYKEELSKMEKEIM 889
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEK-----AERYKELKAELRELELAL---------LVLRLEELREELEELQEELKEAEEELE 256
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  890 HLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELR 969
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA 336
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  970 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQ----- 1044
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrr 416
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1045 ----------KIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMES 1114
Cdd:TIGR02168  417 erlqqeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                   ....*...
gi 1034558166 1115 VMKEQEQY 1122
Cdd:TIGR02168  497 LQENLEGF 504
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
252-1122 7.59e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 7.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  252 FQQYKKKVAEKLEKVQAEEEILErnltncekenkrlqercglykSELEILKEKLRQLKEEnnngKEKLrimavknsevma 331
Cdd:TIGR02169  168 FDRKKEKALEELEEVEENIERLD---------------------LIIDEKRQQLERLRRE----REKA------------ 210
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  332 qltESRQSILKLESELENKdEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGF 411
Cdd:TIGR02169  211 ---ERYQALLKEKREYEGY-ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE 286
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  412 KSYLS-KYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTanQLSQSLitcndSQESSKLSSLETEp 490
Cdd:TIGR02169  287 EEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE--ELEREI-----EEERKRRDKLTEE- 358
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  491 vklgghqvaesvkdqnqhtmnkqYEKERQRLvtgiEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKL 570
Cdd:TIGR02169  359 -----------------------YAELKEEL----EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  571 ESEMTKKCSQLLTLEKQLEekivaysSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIclafEKAKKihleQHKEMEK 650
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIA-------GIEAKINELEEEKEDKALEIKKQEWKLEQLAADL----SKYEQ----ELYDLKE 476
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  651 QIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQ-------NQVSEET 723
Cdd:TIGR02169  477 EYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagnrlNNVVVED 556
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  724 IKVRQldSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEE----------VYCLQKELKIKNHSLQETSEQNVILQHTL 793
Cdd:TIGR02169  557 DAVAK--EAIELLKRRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdlVEFDPKYEPAFKYVFGDTLVVEDIEAARR 634
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  794 QQQQQMLQ----------------QETIRNGELEDTQTKLE-KQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLK 856
Cdd:TIGR02169  635 LMGKYRMVtlegelfeksgamtggSRAPRGGILFSRSEPAElQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA 714
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  857 RQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELE-KLQHSTET 935
Cdd:TIGR02169  715 SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEaRLSHSRIP 794
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  936 ELTEALQKrevLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALK 1015
Cdd:TIGR02169  795 EIQAELSK---LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1016 ERNWELKQRAAQVTHLDMTIREHR---GEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMlQNE 1092
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIP-EEE 950
                          890       900       910
                   ....*....|....*....|....*....|.
gi 1034558166 1093 QEISQLKKEIERTQQRMKEMESV-MKEQEQY 1122
Cdd:TIGR02169  951 LSLEDVQAELQRVEEEIRALEPVnMLAIQEY 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
138-995 1.01e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  138 MTKFESIHFELtqsRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDkvLREAENKLEQSQKMVIEKEQSLQESKEEC 217
Cdd:TIGR02168  188 LDRLEDILNEL---ERQLKSLERQAEKAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  218 IKLKVDLLEQTKQGKRAERQRNEA---LYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLY 294
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELqkeLYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  295 KSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELEnkdeilrdkfSLMNENRELKVRVAAQ 374
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA----------SLNNEIERLEARLERL 412
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  375 NERLDLCQQEIESSRVELRSLEKiisqlplkrelfgfksylskyqmssfsnkeDRCIGCCEANKLVISELRIKLAIKEAE 454
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAEL------------------------------KELQAELEELEEELEELQEELERLEEA 462
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  455 IQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMN-------------KQYEKE---- 517
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlselisvdEGYEAAieaa 542
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  518 ----RQRLVTGIEELRTKLIQIEAENSDLKVNMahrtsqfqLIQEELLEKASNSSKLESEMTKKCSQ--LLTLEKQLEEK 591
Cdd:TIGR02168  543 lggrLQAVVVENLNAAKKAIAFLKQNELGRVTF--------LPLDSIKGTEIQGNDREILKNIEGFLgvAKDLVKFDPKL 614
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  592 IVAYSSIAA--KNAELEQELMEKNEKIRSLETNINTEHEKI----CLAFEKAKKIHLEQHKEMEkqIERLEAQLEKKDQQ 665
Cdd:TIGR02168  615 RKALSYLLGgvLVVDDLDNALELAKKLRPGYRIVTLDGDLVrpggVITGGSAKTNSSILERRRE--IEELEEKIEELEEK 692
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  666 FKEQEKTMSMLQQDIICKQHHLESLDRLLTEskgemkkenmkKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLN 745
Cdd:TIGR02168  693 IAELEKALAELRKELEELEEELEQLRKELEE-----------LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  746 QLEGNKEKFEKqlkkkseevycLQKELKiknhslqetseqnvilqhtlqqqqqmlqqetirngELEDTQTKLEKQVSKLE 825
Cdd:TIGR02168  762 EIEELEERLEE-----------AEEELA-----------------------------------EAEAEIEELEAQIEQLK 795
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  826 QELQKQRESSAEklrkmeekcesaaheadlKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQL 905
Cdd:TIGR02168  796 EELKALREALDE------------------LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  906 DMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTT 985
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937
                          890
                   ....*....|
gi 1034558166  986 IKDLTAELRE 995
Cdd:TIGR02168  938 IDNLQERLSE 947
PTZ00121 PTZ00121
MAEBL; Provisional
497-1213 1.07e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  497 QVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEEllEKASNSSKLESEMTK 576
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA--RKAEDAKRVEIARKA 1160
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  577 KCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELmEKNEKIRSLETNINTEHEKiclAFEKAKKIHLEQHKEMEKQIErlE 656
Cdd:PTZ00121  1161 EDARKAEEARKAEDAKKAEAARKAEEVRKAEEL-RKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAE--E 1234
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  657 AQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEIC 736
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA 1314
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  737 KEELVLHLNQLEGNKE-----KFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELE 811
Cdd:PTZ00121  1315 KKADEAKKKAEEAKKKadaakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD 1394
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  812 DTQTKLEKQVSKLEQELQKQRESS-AEKLRKMEE---KCESAAHEADLKRqKVIELTGTARQVKIEMDQYKEELSKMEKE 887
Cdd:PTZ00121  1395 EAKKKAEEDKKKADELKKAAAAKKkADEAKKKAEekkKADEAKKKAEEAK-KADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  888 IMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLET--ELQNAHGELKS-TLRQ 964
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKadEAKKAEEKKKAdELKK 1553
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  965 LQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQEllemdQALKERNWELKQRAAQVthldmtirehRGEMEQ 1044
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE-----EVMKLYEEEKKMKAEEA----------KKAEEA 1618
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1045 KIIKLEgtLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYI- 1123
Cdd:PTZ00121  1619 KIKAEE--LKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKk 1696
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1124 -ATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAH 1202
Cdd:PTZ00121  1697 eAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
                          730
                   ....*....|.
gi 1034558166 1203 LEARMQAEIKK 1213
Cdd:PTZ00121  1777 KEAVIEEELDE 1787
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
151-781 1.46e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 1.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  151 SRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMV--------------IEKEQSLQESKEE 216
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkdlgeeeqlrvkekIGELEAEIASLER 308
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  217 CIKLKVDLLEQT-KQGKRAERQRNEALYNAEELSKAFQQYKKKVA---EKLEKVQAEEEILERNLTNCEKENKRLQERCG 292
Cdd:TIGR02169  309 SIAEKERELEDAeERLAKLEAEIDKLLAEIEELEREIEEERKRRDkltEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  293 LYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVA 372
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  373 AQNERLDLCQQEIESsrvELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNK--------------EDRCIGCCEA-- 436
Cdd:TIGR02169  469 QELYDLKEEYDRVEK---ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgtvaqlgsvGERYATAIEVaa 545
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  437 -----NKLVISELRIKLAIKEAEIQKL--HANLTANQLSQS------------------LITCNDSQESS---------- 481
Cdd:TIGR02169  546 gnrlnNVVVEDDAVAKEAIELLKRRKAgrATFLPLNKMRDErrdlsilsedgvigfavdLVEFDPKYEPAfkyvfgdtlv 625
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  482 --------------KLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMA 547
Cdd:TIGR02169  626 vedieaarrlmgkyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLD 705
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  548 HRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINT-- 625
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDle 785
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  626 ---EHEKICLAFEKAKKIHlEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIickqhhlesldRLLTESKGEMK 702
Cdd:TIGR02169  786 arlSHSRIPEIQAELSKLE-EEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR-----------IDLKEQIKSIE 853
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  703 KENMKKDEALKALQNQVSEETIKVRQLDSALEICK---EELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSL 779
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKkerDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                   ..
gi 1034558166  780 QE 781
Cdd:TIGR02169  934 SE 935
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
877-1290 1.65e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.75  E-value: 1.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  877 YKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQhsteTELTEALQKREVLETELQNAHG 956
Cdd:PRK02224   211 LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLR----ETIAETEREREELAEEVRDLRE 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  957 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKK---QELLEMDQALKERNWELKQRAAqvthldm 1033
Cdd:PRK02224   287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRvaaQAHNEEAESLREDADDLEERAE------- 359
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1034 TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKefimlqnEQEISQLKKEIERTQQRMKEME 1113
Cdd:PRK02224   360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA-------EDFLEELREERDELREREAELE 432
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1114 SVMKEQEQYIAtqykEAIDL---------GQELRLT---------REQVQNSHTELAEARHQQVQAQREIERLSSELEDM 1175
Cdd:PRK02224   433 ATLRTARERVE----EAEALleagkcpecGQPVEGSphvetieedRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1176 KQLSKEKDAHGNhlAEELGASKVREAHLEARMQAEIKKLSAEVESlkeayhmEMISHQENHAKWKISADSQKSSVQQLNE 1255
Cdd:PRK02224   509 DRIERLEERRED--LEELIAERRETIEEKRERAEELRERAAELEA-------EAEEKREAAAEAEEEAEEAREEVAELNS 579
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1034558166 1256 QLEKAKLELE------EAQDTVSNLHQQVQDRNEVIEAANE 1290
Cdd:PRK02224   580 KLAELKERIEslerirTLLAAIADAEDEIERLREKREALAE 620
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
179-950 2.26e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 2.26e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  179 EAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEEciklkvdLLEQTKQGKRAERQRNEAlynAEELSKAFQQYKKK 258
Cdd:TIGR02169  222 EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEE-------ISELEKRLEEIEQLLEEL---NKKIKDLGEEEQLR 291
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  259 VAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEEnnngkekLRIMAVKNSEVMAQLTESRQ 338
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE-------IEEERKRRDKLTEEYAELKE 364
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  339 SILKLESELENKDEilrdkfslmnENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKY 418
Cdd:TIGR02169  365 ELEDLRAELEEVDK----------EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  419 QMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLtaNQLSQSLitcndSQESSKLSSLET-----EPVKL 493
Cdd:TIGR02169  435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY--DRVEKEL-----SKLQRELAEAEAqarasEERVR 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  494 GGHQVAESVKDQNQ--HTMNKQYEKERQRLVTGIE-------------------------------------------EL 528
Cdd:TIGR02169  508 GGRAVEEVLKASIQgvHGTVAQLGSVGERYATAIEvaagnrlnnvvveddavakeaiellkrrkagratflplnkmrdER 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  529 RTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCS-QLLTLEKQLEEK-------IVAYSSIAA 600
Cdd:TIGR02169  588 RDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyRMVTLEGELFEKsgamtggSRAPRGGIL 667
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  601 KNAELEQELMEKNEKIRSLETNINTEHEKIC----LAFEKAKKIHL--EQHKEMEKQIERLEAQLEKKDQQFKEQEKTMS 674
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRrienRLDELSQELSDasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  675 MLQQDIICKQHHLESLDrlltESKGEMKKENMKKDEALKALQNQVSEETIK-VRQLDSALEICKEELVLHLNQLEG--NK 751
Cdd:TIGR02169  748 SLEQEIENVKSELKELE----ARIEELEEDLHKLEEALNDLEARLSHSRIPeIQAELSKLEEEVSRIEARLREIEQklNR 823
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  752 EKFEKQ-LKKKSEEVYCLQKELKIKNHSLQETSEQNvilqhtlqqqqqmlqqetirNGELEDTQTKLEKQVSKLEQ---- 826
Cdd:TIGR02169  824 LTLEKEyLEKEIQELQEQRIDLKEQIKSIEKEIENL--------------------NGKKEELEEELEELEAALRDlesr 883
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  827 --ELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEimhlkrdgenkamhlSQ 904
Cdd:TIGR02169  884 lgDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI---------------PE 948
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034558166  905 LDMILDQTKTELEKKTNAVKELEKLQHSTETELTEAL-------QKREVLETE 950
Cdd:TIGR02169  949 EELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLkrldelkEKRAKLEEE 1001
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
646-1183 3.56e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 3.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  646 KEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIK 725
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKND 115
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  726 VRQldsaleicKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVilqhtlqqqqqmlqqeti 805
Cdd:TIGR04523  116 KEQ--------KNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE------------------ 169
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  806 rngELEDTQTKLEKQVSKLEQELQKQR------ESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKE 879
Cdd:TIGR04523  170 ---ELENELNLLEKEKLNIQKNIDKIKnkllklELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTT 246
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  880 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVK----ELEKLQHSTETELTEALQKR-EVLETELQNA 954
Cdd:TIGR04523  247 EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNqlksEISDLNNQKEQDWNKELKSElKNQEKKLEEI 326
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  955 HGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQEllemDQALKERNWELKQRAAQVTHLDMT 1034
Cdd:TIGR04523  327 QNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE----NQSYKQEIKNLESQINDLESKIQN 402
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1035 IREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMES 1114
Cdd:TIGR04523  403 QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ 482
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1115 VMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKD 1183
Cdd:TIGR04523  483 NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDD 551
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
111-661 4.70e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 4.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  111 QEIKSLREKLNKLRQQnacLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASvpiLEEQIINLEAEVSAQDKVLR 190
Cdd:COG1196    274 LELEELELELEEAQAE---EYELLAELARLEQDIARLEERRRELEERLEELEEELAE---LEEELEELEEELEELEEELE 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  191 EAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEE 270
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  271 EILERNLTNCEKENKRLQERcglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENK 350
Cdd:COG1196    428 EALAELEEEEEEEEEALEEA----AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  351 DEILRDKFSLMNENRELKVRVAAQNERLDlcqqEIESSRVELRSLEKIISQLPLKRElfgfksylskyqmssfsNKEDRC 430
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGV----EAAYEAALEAALAAALQNIVVEDD-----------------EVAAAA 562
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  431 IGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLetepvklgghQVAESVKDQNQHTM 510
Cdd:COG1196    563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL----------GDTLLGRTLVAARL 632
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  511 nkqyEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEE 590
Cdd:COG1196    633 ----EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034558166  591 KIVAYSSIAAKNAELEQELMEKNEKIRSLEtNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEK 661
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELL-EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
936-1315 4.84e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.94  E-value: 4.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  936 ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLE--EKYTTIKDLTAELRECKMEIEDKKQELlemdQA 1013
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPERL----EE 150
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1014 LKERNWELKQRAAQVTHLDMTIREHRGEMEQKiikLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQ 1093
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEEL---LEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1094 EISQLKKEIERTQ--QRMKEMESV------------MKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQV 1159
Cdd:COG4717    228 ELEQLENELEAAAleERLKEARLLlliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1160 QAQREIERLSSE--LEDMKQLSKEKDAHGNHLAEELG-ASKVREAHLEARM---QAEIKKLSAEVESLKEAYHMEMISHQ 1233
Cdd:COG4717    308 QALPALEELEEEelEELLAALGLPPDLSPEELLELLDrIEELQELLREAEEleeELQLEELEQEIAALLAEAGVEDEEEL 387
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1234 ENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVS--NLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEK 1311
Cdd:COG4717    388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                   ....
gi 1034558166 1312 AEDI 1315
Cdd:COG4717    468 DGEL 471
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
558-1301 5.05e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 5.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  558 EELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKA 637
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  638 KKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALK---- 713
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKkeke 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  714 ---ALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 790
Cdd:pfam02463  336 eieELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  791 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLR--KMEEKCESAAHEADLKRQKVIELTGTAR 868
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELelKKSEDLLKETQLVKLQEQLELLLSRQKL 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  869 QVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLD----------MILDQTKTELEKKTNAVKELEKLQHSTETELT 938
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDlgvavenykvAISTAVIVEVSATADEVEERQKLVRALTELPL 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERN 1018
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1019 WELKQRA-AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQ 1097
Cdd:pfam02463  656 EGLAEKSeVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1098 LKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQ 1177
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAE 815
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1178 LSKEKDAHGNHLAEELgASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQL 1257
Cdd:pfam02463  816 LLEEEQLLIEQEEKIK-EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1034558166 1258 EKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTR 1301
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPE 938
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
932-1138 6.25e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 6.25e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  932 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMD 1011
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1012 QALKERNWELkQRAAQVTHLDMTIR-EHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQ 1090
Cdd:COG4942    104 EELAELLRAL-YRLGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1034558166 1091 NEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELR 1138
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
816-1305 9.31e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.03  E-value: 9.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  816 KLEKQVSKLEQELQKQRESSAEKLRKMEEKcesaAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDG 895
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKK----EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL 196
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  896 ENKAMHLSQLDMiLDQTKTELEKKTNavkELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA 975
Cdd:TIGR04523  197 LKLELLLSNLKK-KIQKNKSLESQIS---ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEK 272
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  976 QLSLEEKYTTIKDLTAELRECKMEIEDKKQE--------------------------LLEMDQALKERNWELKQRAAQVT 1029
Cdd:TIGR04523  273 QKELEQNNKKIKELEKQLNQLKSEISDLNNQkeqdwnkelkselknqekkleeiqnqISQNNKIISQLNEQISQLKKELT 352
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1030 HLDMTIREHRGEMEQK---IIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQ 1106
Cdd:TIGR04523  353 NSESENSEKQRELEEKqneIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK 432
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1107 QRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHG 1186
Cdd:TIGR04523  433 ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1187 NHLAEELGASKVREAHLEarmqAEIKKLSAEVESLKEayHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEE 1266
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLE----SEKKEKESKISDLED--ELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEE 586
                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1034558166 1267 AQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAK 1305
Cdd:TIGR04523  587 KQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
441-972 1.01e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  441 ISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEpvklgghqVAESVKDQN-QHTMNKQYEKERQ 519
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE--------LARLEQDIArLEERRRELEERLE 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  520 RLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIA 599
Cdd:COG1196    320 ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  600 AKNAELEQELMEKNEKIRSLETNINTEHEKIcLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQD 679
Cdd:COG1196    400 AQLEELEEAEEALLERLERLEEELEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  680 IICKQHHLESLDRLLtESKGEMKKENMKKDEALKALQN---------QVSEETIKVRQLDSALEICKEELVLHLN-QLEG 749
Cdd:COG1196    479 LAELLEELAEAAARL-LLLLEAEADYEGFLEGVKAALLlaglrglagAVAVLIGVEAAYEAALEAALAAALQNIVvEDDE 557
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  750 NKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTqTKLEKQVSKLEQELQ 829
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT-LLGRTLVAARLEAAL 636
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  830 KQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMIL 909
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034558166  910 DQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVL 972
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1035-1224 1.78e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 1.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1035 IREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMES 1114
Cdd:COG4942     32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1115 VMKEQEQ---------------------YIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELE 1173
Cdd:COG4942    112 ALYRLGRqpplalllspedfldavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALE 191
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034558166 1174 DMKQlskEKDAHGNHLAEELGASKVREAHL---EARMQAEIKKLSAEVESLKEA 1224
Cdd:COG4942    192 ALKA---ERQKLLARLEKELAELAAELAELqqeAEELEALIARLEAEAAAAAER 242
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1095-1314 1.84e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 1.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1095 ISQLKKEIERTQQRMKEMES-------VMKEQEQYI---------ATQYKE---------AIDLGQELRLTREQVQNSHT 1149
Cdd:COG1196    167 ISKYKERKEEAERKLEATEEnlerledILGELERQLeplerqaekAERYRElkeelkeleAELLLLKLRELEAELEELEA 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1150 ELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAyHMEM 1229
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL-EEEL 325
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1230 ISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGH 1309
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405

                   ....*
gi 1034558166 1310 EKAED 1314
Cdd:COG1196    406 EEAEE 410
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
985-1299 1.84e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 1.84e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  985 TIKDLTAELRECKMEIEDKKQELLEM---------DQALkernwELKQRAA---QVTHLDMTIREH---RGEMEQKIIKL 1049
Cdd:COG4913    156 DIRALKARLKKQGVEFFDSFSAYLARlrrrlgigsEKAL-----RLLHKTQsfkPIGDLDDFVREYmleEPDTFEAADAL 230
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1050 EG---TLEKSELELKECNKQIESL------NDKLQNAKEQLREKEFIM-----LQNEQEISQLKKEIERTQQRMKEMEsv 1115
Cdd:COG4913    231 VEhfdDLERAHEALEDAREQIELLepirelAERYAAARERLAELEYLRaalrlWFAQRRLELLEAELEELRAELARLE-- 308
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1116 mkEQEQyiatqykeaiDLGQELRLTREQVQNSHTELAEARHQQVQA-QREIERLSSELEDMKQLSKEKDAhgnhLAEELG 1194
Cdd:COG4913    309 --AELE----------RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEA----LLAALG 372
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1195 ASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEmishqenhakwkisADSQKSSVQQLNEQLEKAKLELEEAQDTVSNL 1274
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEA--------------LAEAEAALRDLRRELRELEAEIASLERRKSNI 438
                          330       340
                   ....*....|....*....|....*
gi 1034558166 1275 HQQVQdrnEVIEAANEALLTKESEL 1299
Cdd:COG4913    439 PARLL---ALRDALAEALGLDEAEL 460
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
721-1319 3.00e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 3.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  721 EETIKVRQLDSALEICKEELvlhlNQLEGNKEKFEKQLKKKSEEVYCLQKEL--KIKNHSLQETSEQNVILQHTLQQQQQ 798
Cdd:TIGR02169  160 DEIAGVAEFDRKKEKALEEL----EEVEENIERLDLIIDEKRQQLERLRRERekAERYQALLKEKREYEGYELLKEKEAL 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  799 MLQQETIRN--GELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESaahEADLKRQKVIELTGTARQVKIEMDQ 876
Cdd:TIGR02169  236 ERQKEAIERqlASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE---EQLRVKEKIGELEAEIASLERSIAE 312
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  877 YKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKlqhstetELTEALQKREVLETELQNAHG 956
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE-------ELEDLRAELEEVDKEFAETRD 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  957 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVthldMTIR 1036
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLA 461
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1037 EHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE----KEFIMLQNEQEISQLKKEIERTQQRMKEM 1112
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgravEEVLKASIQGVHGTVAQLGSVGERYATAI 541
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1113 ESVMKEQEQYIATQ----YKEAIDLGQELRLTR------EQVQNSHTEL----------------------AEARHQQVQ 1160
Cdd:TIGR02169  542 EVAAGNRLNNVVVEddavAKEAIELLKRRKAGRatflplNKMRDERRDLsilsedgvigfavdlvefdpkyEPAFKYVFG 621
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1161 AQREIERLSSELEDMKQ----------LSKEKDAHGNHLAEELGAS-KVREAHLEARMQAEIKKLSAEVESLkeayhMEM 1229
Cdd:TIGR02169  622 DTLVVEDIEAARRLMGKyrmvtlegelFEKSGAMTGGSRAPRGGILfSRSEPAELQRLRERLEGLKRELSSL-----QSE 696
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1230 ISHQENH---AKWKISADSQKSS-----VQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTR 1301
Cdd:TIGR02169  697 LRRIENRldeLSQELSDASRKIGeiekeIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776
                          650
                   ....*....|....*...
gi 1034558166 1302 LQAKISGHEKAEDIKFLP 1319
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIP 794
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
111-402 3.11e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 3.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  111 QEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLE-SAQQQAASVPILEEQIINLEAEVSAQDKVL 189
Cdd:TIGR02168  740 AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEaQIEQLKEELKALREALDELRAELTLLNEEA 819
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  190 REAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAF---QQYKKKVAEKLEKV 266
Cdd:TIGR02168  820 ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERaslEEALALLRSELEEL 899
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  267 QAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEE-NNNGKEKLRIMAVKNSEVMAQLTESRQSILKLES 345
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034558166  346 ELENKDEIlrdKFSLMNENRELKvrvaaqnERLDLCQQEIESSRVELRSLEKIISQL 402
Cdd:TIGR02168  980 KIKELGPV---NLAAIEEYEELK-------ERYDFLTAQKEDLTEAKETLEEAIEEI 1026
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
562-1146 5.20e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 57.88  E-value: 5.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  562 EKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKiclAFEKAKKIH 641
Cdd:pfam01576   19 ERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEE---EEERSQQLQ 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  642 LEQhKEMEKQIERLEAQLEkkdqqfkEQEKTMSMLQQDIICKQHHLESLDR---LLTESKGEMKKENMKKDEALKALQNQ 718
Cdd:pfam01576   96 NEK-KKMQQHIQDLEEQLD-------EEEAARQKLQLEKVTTEAKIKKLEEdilLLEDQNSKLSKERKLLEERISEFTSN 167
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  719 VSEETIKVR---QLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQ 795
Cdd:pfam01576  168 LAEEEEKAKslsKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQA 247
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  796 QQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQR--ESSAEKLRK------------MEEKCESAAHEADLKRQKVI 861
Cdd:pfam01576  248 ALARLEEETAQKNNALKKIRELEAQISELQEDLESERaaRNKAEKQRRdlgeelealkteLEDTLDTTAAQQELRSKREQ 327
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  862 ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNavkELEKLQHSTETELTEAL 941
Cdd:pfam01576  328 EVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENA---ELQAELRTLQQAKQDSE 404
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  942 QKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKErnwEL 1021
Cdd:pfam01576  405 HKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQE---ET 481
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1022 KQRAAQVTHLDMTIREHRGEMEQkiiklegtLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 1101
Cdd:pfam01576  482 RQKLNLSTRLRQLEDERNSLQEQ--------LEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRE 553
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1034558166 1102 IERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQN 1146
Cdd:pfam01576  554 LEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSN 598
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
500-1076 6.26e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 6.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  500 ESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKAS----NSSKLESEMT 575
Cdd:pfam15921  248 EALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVS 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  576 KKCSQLLTLEKQLEEKIvayssiaaknAELEQELMEKNEKIrsleTNINTEHEKIClafekakkihlEQHKEMEKQIERL 655
Cdd:pfam15921  328 QLRSELREAKRMYEDKI----------EELEKQLVLANSEL----TEARTERDQFS-----------QESGNLDDQLQKL 382
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  656 EAQLEKKDQQF---KEQEK-----------TMSMLQQDIICKQHHLESLDRLLTESKGEMKKEnmkKDEALKALQNQvSE 721
Cdd:pfam15921  383 LADLHKREKELsleKEQNKrlwdrdtgnsiTIDHLRRELDDRNMEVQRLEALLKAMKSECQGQ---MERQMAAIQGK-NE 458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  722 ETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQ-KELKIKNHSLQETSEQNVILQHTLQQQQQML 800
Cdd:pfam15921  459 SLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQeKERAIEATNAEITKLRSRVDLKLQELQHLKN 538
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  801 QQETIRNGELEDTQTKLE-----KQVSKLEQEL--------QKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTA 867
Cdd:pfam15921  539 EGDHLRNVQTECEALKLQmaekdKVIEILRQQIenmtqlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDA 618
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  868 RQVKIEmdqykEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNavkELEKLQHSTETELTEALQKREVL 947
Cdd:pfam15921  619 KIRELE-----ARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN---ELNSLSEDYEVLKRNFRNKSEEM 690
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  948 ETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWE---LKQR 1024
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEkhfLKEE 770
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034558166 1025 AAQVTHLDMTIREHRGEM--------------EQKIIKLEGTLEKSELELKECNKQI-----ESLNDKLQN 1076
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMagelevlrsqerrlKEKVANMEVALDKASLQFAECQDIIqrqeqESVRLKLQH 841
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1084-1330 9.52e-08

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 56.95  E-value: 9.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1084 KEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIAtQYKEA---IDLGQELRLTREQVQNSHTELAEARHQQVQ 1160
Cdd:COG3206    159 EAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALE-EFRQKnglVDLSEEAKLLLQQLSELESQLAEARAELAE 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1161 AQREIERLSSELEDMKQLSKE--KDAHGNHLAEELGASKVREAHLEARMQAE---IKKLSAEVESLKEAYHMEMishQEN 1235
Cdd:COG3206    238 AEARLAALRAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQEA---QRI 314
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1236 HAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRnEVIEAANEALLTKeseltRLQAKISGHEKAEDI 1315
Cdd:COG3206    315 LASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREV-EVARELYESLLQR-----LEEARLAEALTVGNV 388
                          250
                   ....*....|....*
gi 1034558166 1316 KFLPAPFTSPTEIMP 1330
Cdd:COG3206    389 RVIDPAVVPLKPVSP 403
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
725-1301 1.23e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 56.52  E-value: 1.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  725 KVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEvycLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET 804
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREA---LQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEE 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  805 IRN--GELEDTQTKLEKQVSK---------LEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQkviELTGTARQVKIE 873
Cdd:TIGR00618  272 LRAqeAVLEETQERINRARKAaplaahikaVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ---QSSIEEQRRLLQ 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  874 MDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAV-KELEKLQHSTETELTEaLQKREVLETELQ 952
Cdd:TIGR00618  349 TLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLcKELDILQREQATIDTR-TSAFRDLQGQLA 427
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  953 NAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLD 1032
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLC 507
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1033 MTIREHRGEMEQKIIK--LEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMK 1110
Cdd:TIGR00618  508 GSCIHPNPARQDIDNPgpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIP 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1111 EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHgnhla 1190
Cdd:TIGR00618  588 NLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVRE----- 662
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1191 eELGASKVREAHLEARMQAEIKKLSAEVESLkeAYHMEMISH-------QENHAK--------WKISADSQKSSVQQLNE 1255
Cdd:TIGR00618  663 -HALSIRVLPKELLASRQLALQKMQSEKEQL--TYWKEMLAQcqtllreLETHIEeydrefneIENASSSLGSDLAARED 739
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1256 QLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTR 1301
Cdd:TIGR00618  740 ALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAA 785
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
147-680 1.23e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 1.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  147 ELTQSRAKVSMLESAQQQaasvpiLEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLE 226
Cdd:COG1196    254 ELEELEAELAELEAELEE------LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  227 QTKQGKRAERQRNEALYNAEELSKAFQQykkkVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLR 306
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  307 QLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIE 386
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  387 SSRVELRSLEKIISQLPLKRELFGFKSYLSKyqmssfsNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANq 466
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAAL-------LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED- 555
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  467 lSQSLITCNDSQESSK--------LSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAE 538
Cdd:COG1196    556 -DEVAAAAIEYLKAAKagratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  539 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRS 618
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034558166  619 LETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI 680
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
110-394 1.44e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.60  E-value: 1.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  110 DQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQ-QQAASVPILEEQIINLEAEVSAQDKV 188
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIsALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  189 LREAENKLEQSQKMVIEKEQSLQESKEEciklkvdLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQA 268
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAEAEAE-------IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  269 eeeiLERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEEnnngKEKLRIMAVKNSEVMAQLTESRQSilkLESELE 348
Cdd:TIGR02168  829 ----LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL----IEELESELEALLNERASLEEALAL---LRSELE 897
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166  349 NKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS 394
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
147-402 1.61e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 1.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  147 ELTQSRAKVSMLESAQQQAASvpiLEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLE 226
Cdd:COG1196    223 KELEAELLLLKLRELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR 299
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  227 QTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLR 306
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  307 QLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIE 386
Cdd:COG1196    380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
                          250
                   ....*....|....*.
gi 1034558166  387 SSRVELRSLEKIISQL 402
Cdd:COG1196    460 ALLELLAELLEEAALL 475
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1043-1224 2.58e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 2.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1043 EQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQY 1122
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1123 IATQYKEAIDLGQ----ELRLTREQVQNS------HTELAEARHQQVQAQR----EIERLSSELEDMKQLSKEKDAHGNH 1188
Cdd:COG4942    106 LAELLRALYRLGRqpplALLLSPEDFLDAvrrlqyLKYLAPARREQAEELRadlaELAALRAELEAERAELEALLAELEE 185
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1034558166 1189 LAEELGASKVREAHLEARMQAEIKKLSAEVESLKEA 1224
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
948-1155 2.73e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 54.84  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  948 ETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAA- 1026
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARa 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1027 ------QVTHLDM------------------TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 1082
Cdd:COG3883     95 lyrsggSVSYLDVllgsesfsdfldrlsalsKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1083 EKefiMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEAR 1155
Cdd:COG3883    175 AQ---QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
906-1314 2.86e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 2.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  906 DMILDQTKTElEKKTNAVKELEKLqHSTETELTEALQKREVLE--TELQNAHGELKSTLRQLQELRDVL-----QKAQLS 978
Cdd:COG4913    215 EYMLEEPDTF-EAADALVEHFDDL-ERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALrlwfaQRRLEL 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  979 LEEKYTT----IKDLTAELRECKMEIEDKKQELLEMDQALKERNW----ELKQRAAQVTHLDMTIREHRGEMEQKIIKLE 1050
Cdd:COG4913    293 LEAELEElraeLARLEAELERLEARLDALREELDELEAQIRGNGGdrleQLEREIERLERELEERERRRARLEALLAALG 372
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1051 GTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFimlQNEQEISQLKKEIERTQQRMKEMES---------------- 1114
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALA---EAEAALRDLRRELRELEAEIASLERrksniparllalrdal 449
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1115 -------------------VMKEQ-------EQYI----------------ATQYKEAIDLGQELRLTREQVQNSHTELA 1152
Cdd:COG4913    450 aealgldeaelpfvgelieVRPEEerwrgaiERVLggfaltllvppehyaaALRWVNRLHLRGRLVYERVRTGLPDPERP 529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1153 EARHQQVQAQREIER------LSSEL---------EDMKQLSKEKDA-------HGNHLAEE------------LGAS-K 1197
Cdd:COG4913    530 RLDPDSLAGKLDFKPhpfrawLEAELgrrfdyvcvDSPEELRRHPRAitragqvKGNGTRHEkddrrrirsryvLGFDnR 609
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1198 VREAHLEARM---QAEIKKLSAEVESLKEAYHmEMISHQENHAKWK------ISADSQKSSVQQLNEQLEkaklELEEAQ 1268
Cdd:COG4913    610 AKLAALEAELaelEEELAEAEERLEALEAELD-ALQERREALQRLAeyswdeIDVASAEREIAELEAELE----RLDASS 684
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1269 DTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAED 1314
Cdd:COG4913    685 DDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD 730
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
505-1154 3.43e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.36  E-value: 3.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  505 QNQHTMNKQYEKERQRLVTGIEELRTKLIqiEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTL 584
Cdd:TIGR00618  242 HAYLTQKREAQEEQLKKQQLLKQLRARIE--ELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSK 319
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  585 EKQLEEKIVAYSSIAAKNAELEQElmeknekiRSLETNINTEHEKICLAFEKAKKI--HLEQHKEMEKQIERLEAQLEKK 662
Cdd:TIGR00618  320 MRSRAKLLMKRAAHVKQQSSIEEQ--------RRLLQTLHSQEIHIRDAHEVATSIreISCQQHTLTQHIHTLQQQKTTL 391
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  663 DQQFKEQEKTMSMLQ--QDIICKQHHLESLDRL-LTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEE 739
Cdd:TIGR00618  392 TQKLQSLCKELDILQreQATIDTRTSAFRDLQGqLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER 471
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  740 LvlhlnQLEGNKEKFEKQLKKKSEEVYCLQKELKiknhSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEK 819
Cdd:TIGR00618  472 E-----QQLQTKEQIHLQETRKKAVVLARLLELQ----EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLET 542
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  820 QVSKLEQELQKQRESSAEKLRKMEEKCESAAHEAdLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK- 898
Cdd:TIGR00618  543 SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILT-QCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKl 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  899 --AMHLSQLDMILDQTKTELEKKTNAVK--ELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQK 974
Cdd:TIGR00618  622 qpEQDLQDVRLHLQQCSQELALKLTALHalQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  975 AQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLE 1054
Cdd:TIGR00618  702 CQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELS 781
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1055 KSELELKECNKQIESLNDKLQNAKEQLREK-EFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEqeqyIATQYKEAIDL 1133
Cdd:TIGR00618  782 HLAAEIQFFNRLREEDTHLLKTLEAEIGQEiPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGE----ITHQLLKYEEC 857
                          650       660
                   ....*....|....*....|.
gi 1034558166 1134 GQELRLTREQVQNSHTELAEA 1154
Cdd:TIGR00618  858 SKQLAQLTQEQAKIIQLSDKL 878
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
960-1168 3.44e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 3.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  960 STLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECkmeiedkkQELLEMDQALKERNWELKQRAAqvthLDMTIREHR 1039
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDAL--------QERREALQRLAEYSWDEIDVAS----AEREIAELE 674
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1040 GEMEQkiiklegtLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 1119
Cdd:COG4913    675 AELER--------LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLE 746
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1034558166 1120 EQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHqqvQAQREIERL 1168
Cdd:COG4913    747 LRALLEERFAAALGDAVERELRENLEERIDALRARLN---RAEEELERA 792
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
505-1268 3.46e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.44  E-value: 3.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  505 QNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEmtkkcSQLLTL 584
Cdd:TIGR00606  308 HNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATR-----LELDGF 382
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  585 EKQleekivAYSSIAAKNA-ELEQELMEknEKIRSLETNINTEHEKICLAFEKAKKIHLEQhKEMEKQIERLEAQLEKKD 663
Cdd:TIGR00606  383 ERG------PFSERQIKNFhTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADEIRDEK-KGLGRTIELKKEILEKKQ 453
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  664 QQFKEQEKTMSMLQ---QDIICKQHHLESLDRLLTESKGEMKKENMKKDEalKALQNQVSEETIKVRQLDSALEickeel 740
Cdd:TIGR00606  454 EELKFVIKELQQLEgssDRILELDQELRKAERELSKAEKNSLTETLKKEV--KSLQNEKADLDRKLRKLDQEME------ 525
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  741 vlhlnQLEGNKEKFEKQLKKKSEEVYCLQKELKIK-NHSLQETSEQNVILQHTLQQQQQMLQQETIRngELEDTQTKLEK 819
Cdd:TIGR00606  526 -----QLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsRHSDELTSLLGYFPNKKQLEDWLHSKSKEIN--QTRDRLAKLNK 598
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  820 QVSKLEQ---ELQKQRESSAEKLRKMEEK----CESAAHEADLKRQKViELTGTARQVKI------EMDQYKEELSKMEK 886
Cdd:TIGR00606  599 ELASLEQnknHINNELESKEEQLSSYEDKlfdvCGSQDEESDLERLKE-EIEKSSKQRAMlagataVYSQFITQLTDENQ 677
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  887 EIMHL-KRDGENKAmhlsQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQL 965
Cdd:TIGR00606  678 SCCPVcQRVFQTEA----ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKL 753
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  966 QELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKK-QELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQ 1044
Cdd:TIGR00606  754 QKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTiMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQE 833
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1045 KIIKLEGTLEKSELELK---ECNKQIESLNDKL-----------------QNAKEQLREKEFIMLQNEQEISQLKKEIER 1104
Cdd:TIGR00606  834 KQHELDTVVSKIELNRKliqDQQEQIQHLKSKTnelkseklqigtnlqrrQQFEEQLVELSTEVQSLIREIKDAKEQDSP 913
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1105 TQQRMKEMesvMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAE--------ARHQQVQAQREIERLSSELEDMK 1176
Cdd:TIGR00606  914 LETFLEKD---QQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDienkiqdgKDDYLKQKETELNTVNAQLEECE 990
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1177 QLSKEKDAHGNHLAEELGASKVREAHLEARM-----QAEIKKLSAEVES-LKEAYHMEMISHQENHAKWKISADSQKSS- 1249
Cdd:TIGR00606  991 KHQEKINEDMRLMRQDIDTQKIQERWLQDNLtlrkrENELKEVEEELKQhLKEMGQMQVLQMKQEHQKLEENIDLIKRNh 1070
                          810       820
                   ....*....|....*....|....*
gi 1034558166 1250 ------VQQLNEQLEKAKLELEEAQ 1268
Cdd:TIGR00606 1071 vlalgrQKGYEKEIKHFKKELREPQ 1095
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
814-1225 4.13e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 54.75  E-value: 4.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  814 QTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKR 893
Cdd:pfam05557    4 LIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKK 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  894 DGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREvletELQNAHGELKSTLRQLQELRDVLQ 973
Cdd:pfam05557   84 YLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELE----ELQERLDLLKAKASEAEQLRQNLE 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  974 KAQLSLEEKYTTIKDLTAELR---ECKMEIEDKKQELLEMDQALKernwELKQRAAQVTHLDMTIR-------------- 1036
Cdd:pfam05557  160 KQQSSLAEAEQRIKELEFEIQsqeQDSEIVKNSKSELARIPELEK----ELERLREHNKHLNENIEnklllkeevedlkr 235
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1037 --EHRGEMEQKIIKLEGTLEKSELELKECNK-----------------QIESLNDKLQNAKEQLREKEFIMLQNEQEISQ 1097
Cdd:pfam05557  236 klEREEKYREEAATLELEKEKLEQELQSWVKlaqdtglnlrspedlsrRIEQLQQREIVLKEENSSLTSSARQLEKARRE 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1098 LKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQReIERLSSELEDMKQ 1177
Cdd:pfam05557  316 LEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLLER-IEEAEDMTQKMQA 394
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1034558166 1178 LSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLS-AEVESLKEAY 1225
Cdd:pfam05557  395 HNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESlADPSYSKEEV 443
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
954-1174 4.77e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 4.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  954 AHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDM 1033
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1034 TIREHRGEMEQKIIKLEGTLEKSELEL---KECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMK 1110
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034558166 1111 EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNshtELAEARHQQVQAQREIERLSSELED 1174
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAA---ELAELQQEAEELEALIARLEAEAAA 238
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
804-1281 5.39e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 5.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  804 TIRNGELEDTQTKLEKQVSKLEQELQKQR-ESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK-IEMDQYKEEL 881
Cdd:COG4913    268 RERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  882 SKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEkktNAVKELEKLQHSTETELTEALQKRevleTELQNAHGELKST 961
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFA---ALRAEAAALLEALEEELEALEEAL----AEAEAALRDLRRE 420
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  962 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAElrECKMEIEDKK--QELLEMDQalKERNWEL----------------KQ 1023
Cdd:COG4913    421 LRELEAEIASLERRKSNIPARLLALRDALAE--ALGLDEAELPfvGELIEVRP--EEERWRGaiervlggfaltllvpPE 496
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1024 RAAQV------THLDMTIREHRGEMEQKIIKLEGTLEKS---ELELKEcNKQIESLNDKLQ------------------- 1075
Cdd:COG4913    497 HYAAAlrwvnrLHLRGRLVYERVRTGLPDPERPRLDPDSlagKLDFKP-HPFRAWLEAELGrrfdyvcvdspeelrrhpr 575
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1076 -----------------NAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELR 1138
Cdd:COG4913    576 aitragqvkgngtrhekDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE 655
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1139 LTREQVqnshtELAEARHQQVQAQREIERL---SSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLE---ARMQAEIK 1212
Cdd:COG4913    656 YSWDEI-----DVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEkelEQAEEELD 730
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1213 KLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDR 1281
Cdd:COG4913    731 ELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNRE 799
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
534-1217 6.49e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.34  E-value: 6.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  534 QIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKcSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKN 613
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEN-KDLIKENNATRHLCNLLKETCARSAEKTKKYEYER 178
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  614 EKIRSLETNINTEHEKICLAFE----KAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLES 689
Cdd:pfam05483  179 EETRQVYMDLNNNIEKMILAFEelrvQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKD 258
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  690 LDRLLTESKGEMKKenmkKDEALKALQNQVSEETIKVRQLDSALEickeELVLHLNQLEGNKEKFEKQLKKKSEEVYCL- 768
Cdd:pfam05483  259 LTFLLEESRDKANQ----LEEKTKLQDENLKELIEKKDHLTKELE----DIKMSLQRSMSTQKALEEDLQIATKTICQLt 330
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  769 -QKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRN------GELEDTQTKLEKQVSKLEQ--ELQKQRESSAEKL 839
Cdd:pfam05483  331 eEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQrlekneDQLKIITMELQKKSSELEEmtKFKNNKEVELEEL 410
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  840 RKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLdmildqtKTELEKK 919
Cdd:pfam05483  411 KKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDL-------KTELEKE 483
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  920 TNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQkaqlSLEEKYTTIKDltaelreckmE 999
Cdd:pfam05483  484 KLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIE----NLEEKEMNLRD----------E 549
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1000 IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKE 1079
Cdd:pfam05483  550 LESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENK 629
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1080 QLREKEFIMLQNEQEISQLKKEIER-TQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAE----A 1154
Cdd:pfam05483  630 QLNAYEIKVNKLELELASAKQKFEEiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEmvalM 709
                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1155 RHQQVQAQREIERLSSELEDMKqlSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE 1217
Cdd:pfam05483  710 EKHKHQYDKIIEERDSELGLYK--NKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKE 770
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
111-1002 6.97e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 6.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  111 QEIKSLREKLNKLRQ----QNACLVTQNHSLMTKFESIHFEltqsraKVSMLESAQQQAASVPILEEQIIN----LEAEV 182
Cdd:pfam15921   85 HQVKDLQRRLNESNElhekQKFYLRQSVIDLQTKLQEMQME------RDAMADIRRRESQSQEDLRNQLQNtvheLEAAK 158
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  183 SAQDKVLREAENKLEQSQKMVIEKEQSLQESKeeciKLKVDLLEQTkqGKRAERQRNEALYNAEELSKAFQQYKKKVAEK 262
Cdd:pfam15921  159 CLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIR----SILVDFEEAS--GKKIYEHDSMSTMHFRSLGSAISKILRELDTE 232
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  263 LEKVQAEEEILERNLTNCEKENK------------RLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAV----KN 326
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQnkielllqqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEqarnQN 312
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  327 SEVMAQLTESRQSILKLESELENKDEILRDKFslmnenRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLplkr 406
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKI------EELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL---- 382
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  407 eLFGFKSYLSKYQMSSFSNKE--DRCIGcceaNKLVISELRIKLAIKEAEIQKLHAnltanqLSQSLITCNDSQESSKLS 484
Cdd:pfam15921  383 -LADLHKREKELSLEKEQNKRlwDRDTG----NSITIDHLRRELDDRNMEVQRLEA------LLKAMKSECQGQMERQMA 451
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  485 SLEtepvklGGHQVAESVKdqnqhTMNKQYEKERQRLVTGIEELRTKLIQIEAEN---SDLKVNMAHRTSQFQLIQEELl 561
Cdd:pfam15921  452 AIQ------GKNESLEKVS-----SLTAQLESTKEMLRKVVEELTAKKMTLESSErtvSDLTASLQEKERAIEATNAEI- 519
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  562 ekasnsSKLESEMTKKCSQLLTLEKQLEEkivaYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKIclafekakkih 641
Cdd:pfam15921  520 ------TKLRSRVDLKLQELQHLKNEGDH----LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLV----------- 578
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  642 lEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDiicKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSE 721
Cdd:pfam15921  579 -GQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDK---KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQE 654
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  722 ETikvrQLDSALEICKEElvlhLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNvilqhtlqqqqqmlq 801
Cdd:pfam15921  655 RD----QLLNEVKTSRNE----LNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQT--------------- 711
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  802 QETIRNGELEDTQT-KLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEE 880
Cdd:pfam15921  712 RNTLKSMEGSDGHAmKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGE 791
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  881 LSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELeKLQHSTETELTE--------ALQKREVLETELQ 952
Cdd:pfam15921  792 LEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL-KLQHTLDVKELQgpgytsnsSMKPRLLQPASFT 870
                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034558166  953 NAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIED 1002
Cdd:pfam15921  871 RTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQELRSVINEEPT 920
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
809-1028 8.95e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 8.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  809 ELEDTQTKLEKQVSKLEQeLQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEI 888
Cdd:COG4942     28 ELEQLQQEIAELEKELAA-LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  889 MHLKRDGEnKAMHLSQLDMILDQTK-TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 967
Cdd:COG4942    107 AELLRALY-RLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034558166  968 LRDVLQKAQlslEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 1028
Cdd:COG4942    186 ERAALEALK---AERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
879-1266 1.19e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 1.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  879 EELSKMEKEIMHLKrDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGEL 958
Cdd:PRK03918   145 ESREKVVRQILGLD-DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL 223
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  959 ---KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNwELKQRAAQVthldMTI 1035
Cdd:PRK03918   224 eklEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEY----IKL 298
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1036 REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEfimlqneqeisQLKKEIERTQQRMKEMESV 1115
Cdd:PRK03918   299 SEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK-----------ELEKRLEELEERHELYEEA 367
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1116 MKEQEQyiATQYKEaidlgqelRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGA 1195
Cdd:PRK03918   368 KAKKEE--LERLKK--------RLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGK 437
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1196 SKV--------REAHLEARMQAEIKKLSAEVESLKEAyhMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEE 1266
Cdd:PRK03918   438 CPVcgrelteeHRKELLEEYTAELKRIEKELKEIEEK--ERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKK 514
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
512-1123 1.23e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 1.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  512 KQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 591
Cdd:TIGR04523  134 KENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKN 213
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  592 ---IVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIhLEQHKEMEKQIERLEAQLEKKDQQFKE 668
Cdd:TIGR04523  214 kslESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI-KKQLSEKQKELEQNNKKIKELEKQLNQ 292
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  669 QEKTMSMLQQDiicKQHHLESldrllteskgEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELvlhlNQLE 748
Cdd:TIGR04523  293 LKSEISDLNNQ---KEQDWNK----------ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEL----TNSE 355
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  749 GNKEKFEKQLKKKSEEVYCLQKElkiknhslqetseqnvilqhtlqqqqqmlqqetirNGELEDTQTKLEKQVSKLEQEL 828
Cdd:TIGR04523  356 SENSEKQRELEEKQNEIEKLKKE-----------------------------------NQSYKQEIKNLESQINDLESKI 400
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  829 QKQRESSAEKlrkmEEKCESAAHEADLKRQkvieltgtarqvkiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMI 908
Cdd:TIGR04523  401 QNQEKLNQQK----DEQIKKLQQEKELLEK--------------EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT 462
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  909 LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKrevletelqnaHGELKSTLRQLQELRDVLQKAQLSLEEKyttIKD 988
Cdd:TIGR04523  463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE-----------LKKLNEEKKELEEKVKDLTKKISSLKEK---IEK 528
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  989 LTAELRECKMEIEDKKQELLEMDQALKERNWElkqraaqvthldmtirEHRGEMEQKIIKLEGTLEKSELELKECNKQIE 1068
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELKKENLE----------------KEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1069 SLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYI 1123
Cdd:TIGR04523  593 QKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEV 647
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
190-830 1.37e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  190 REAENKLEQSQkmviEKEQSLQeskeeciklkvDLL-EQTKQGKRAERQRNEALyNAEELSKAFQQYKKKV-AEKLEKVQ 267
Cdd:COG1196    175 EEAERKLEATE----ENLERLE-----------DILgELERQLEPLERQAEKAE-RYRELKEELKELEAELlLLKLRELE 238
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  268 AEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRimavknsEVMAQLTESRQSIlklESEL 347
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-------ELLAELARLEQDI---ARLE 308
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  348 ENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELfgfksylskyQMSSFSNKE 427
Cdd:COG1196    309 ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE----------AEAELAEAE 378
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  428 DrcigccEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQ 507
Cdd:COG1196    379 E------ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  508 htmnkQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLE--------KASNSSKLESEMTKKCS 579
Cdd:COG1196    453 -----ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyegflegvKAALLLAGLRGLAGAVA 527
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  580 QLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKnEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQ-----IER 654
Cdd:COG1196    528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAA-AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaavdlVAS 606
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  655 LEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSAle 734
Cdd:COG1196    607 DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL-- 684
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  735 icKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQ 814
Cdd:COG1196    685 --AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762
                          650
                   ....*....|....*.
gi 1034558166  815 TKLEKQVSKLEQELQK 830
Cdd:COG1196    763 EELERELERLEREIEA 778
PRK12704 PRK12704
phosphodiesterase; Provisional
1048-1212 1.39e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 52.86  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1048 KLEGTLEKSELELKECNKQIESLN-DKLQNAKEQLREKEfimLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 1126
Cdd:PRK12704    32 KIKEAEEEAKRILEEAKKEAEAIKkEALLEAKEEIHKLR---NEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKR 108
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1127 YKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSE------LEDMKQLSKEkDAhgnhlaeelgASKVRE 1200
Cdd:PRK12704   109 EEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEeakeilLEKVEEEARH-EA----------AVLIKE 177
                          170
                   ....*....|..
gi 1034558166 1201 AHLEARMQAEIK 1212
Cdd:PRK12704   178 IEEEAKEEADKK 189
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
755-1298 1.43e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 52.90  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  755 EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTlqqqqqmlqqetirngELEDTQ-TKLEKQVSKLEQELQKQRE 833
Cdd:pfam10174  198 EVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVI----------------EMKDTKiSSLERNIRDLEDEVQMLKT 261
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  834 SSaekLRKMEEkcesaaHEADLKRQKVIEltGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTK 913
Cdd:pfam10174  262 NG---LLHTED------REEEIKQMEVYK--SHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLK 330
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  914 TELEKKTNAVKELEKLQHSTETELTEA---LQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKyttIKDLT 990
Cdd:pfam10174  331 ESLTAKEQRAAILQTEVDALRLRLEEKesfLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKK---IENLQ 407
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  991 AELReckmeieDKKQELLEmdqaLKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEgtlEKSELELKECNKQIESL 1070
Cdd:pfam10174  408 EQLR-------DKDKQLAG----LKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLK---EQREREDRERLEELESL 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1071 NDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTRE-------- 1142
Cdd:pfam10174  474 KKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNaeeavrtn 553
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1143 -----QVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLaeelgASKVREAHLEARMQAEIKKLSAE 1217
Cdd:pfam10174  554 peindRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAEL-----ESLTLRQMKEQNKKVANIKHGQQ 628
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1218 VESLKEAYHMEMISHQENHAKwkisADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRN--------------- 1282
Cdd:pfam10174  629 EMKKKGAQLLEEARRREDNLA----DNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDghltnlraerrkqle 704
                          570
                   ....*....|....*.
gi 1034558166 1283 EVIEAANEALLTKESE 1298
Cdd:pfam10174  705 EILEMKQEALLAAISE 720
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
593-1226 1.57e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 1.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  593 VAYSSIAAKNAELEQELMEkneKIRSLETNINTEhEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT 672
Cdd:TIGR04523   22 VGYKNIANKQDTEEKQLEK---KLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDK 97
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  673 MSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEAlKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKE 752
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKEN-KKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN 176
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  753 KFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLeQELQKQR 832
Cdd:TIGR04523  177 LLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI-SNTQTQL 255
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  833 ESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEE-----LSKMEKEIMHLKRDGENKAMHLSQLDM 907
Cdd:TIGR04523  256 NQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEIQNQISQNNK 335
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  908 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIK 987
Cdd:TIGR04523  336 IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIK 415
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTirehRGEMEQKIIKLEGTLEKSELELKECNKQI 1067
Cdd:TIGR04523  416 KLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT----RESLETQLKVLSRSINKIKQNLEQKQKEL 491
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1068 ESLNDKLQNAKEQLRekefimlQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQElrLTREQVQNS 1147
Cdd:TIGR04523  492 KSKEKELKKLNEEKK-------ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE--LKKENLEKE 562
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1148 HTELAEARHQQVQAQREIERLSSEL-EDMKQLSKEKDAHGNHLAEELGASKVREAHLEaRMQAEIKKLSAEVESLKEAYH 1226
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKqELIDQKEKEKKDLIKEIEEKEKKISSLEKELE-KAKKENEKLSSIIKNIKSKKN 641
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
873-1085 1.66e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 1.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  873 EMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQ 952
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  953 NAHGELKSTLRQLQELRD-------VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRA 1025
Cdd:COG4942    101 AQKEELAELLRALYRLGRqpplallLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1026 AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 1085
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
514-995 1.91e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 1.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  514 YEKERQRLVT---GIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTkkcsqllTLEKQLEE 590
Cdd:PRK02224   246 HEERREELETleaEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE-------AVEARREE 318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  591 kivayssIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHlEQHKEMEKQIERLEAQLEKKDQQFKEQE 670
Cdd:PRK02224   319 -------LEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELR-EEAAELESELEEAREAVEDRREEIEELE 390
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  671 KTMSMLQQ---DIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEEtikvRQLDSA-------LEICKEEL 740
Cdd:PRK02224   391 EEIEELRErfgDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEA----EALLEAgkcpecgQPVEGSPH 466
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  741 VLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKiKNHSLQETSEQnvILQHTLQQQQQMLQQETIRNG--ELEDTQTKLE 818
Cdd:PRK02224   467 VETIEEDRERVEELEAELEDLEEEVEEVEERLE-RAEDLVEAEDR--IERLEERREDLEELIAERRETieEKRERAEELR 543
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  819 KQVSKLEQELQKQRESSAEklrkmeekcesAAHEADLKRQKVIELTGTARQVKIEMDQYkEELSKMEKEIMHLKRDGENK 898
Cdd:PRK02224   544 ERAAELEAEAEEKREAAAE-----------AEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERL 611
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  899 AMHLSQLDMILDQTKTELEKKTNAVKEL---------EKLQHSTET------ELTEALQKREVLETELQNAHGELKSTLR 963
Cdd:PRK02224   612 REKREALAELNDERRERLAEKRERKRELeaefdeariEEAREDKERaeeyleQVEEKLDELREERDDLQAEIGAVENELE 691
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1034558166  964 QLQELRD---VLQKAQLSLEEKY-------TTIKDLTAELRE 995
Cdd:PRK02224   692 ELEELRErreALENRVEALEALYdeaeeleSMYGDLRAELRQ 733
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
114-923 1.94e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 1.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  114 KSLREKLNKLRQQNACLVTQNHSLMTKFESIHfELTQSRAKVSMLESAQQQAAsvpilEEQIINLEAEVSAQDKVLREAE 193
Cdd:pfam02463  250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEK-KLQEEELKLLAKEEEELKSE-----LLKLERRKVDDEEKLKESEKEK 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  194 NKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEIL 273
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  274 ERNLtncekenkrlqercglyKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEI 353
Cdd:pfam02463  404 EKEA-----------------QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  354 LRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKII---SQLPLKRELFGFKSYLSKYQMSSFSNKEDRC 430
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLlalIKDGVGGRIISAHGRLGDLGVAVENYKVAIS 546
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  431 IGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTM 510
Cdd:pfam02463  547 TAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVE 626
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  511 NKQYEKERQRLVTGIEELRTKLIQIEaENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEE 590
Cdd:pfam02463  627 GILKDTELTKLKESAKAKESGLRKGV-SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  591 KIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIhleQHKEMEKQIERLEAQLEKKDQQFKEQE 670
Cdd:pfam02463  706 QREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKS---RLKKEEKEEEKSELSLKEKELAEEREK 782
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  671 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN 750
Cdd:pfam02463  783 TEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  751 KEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK 830
Cdd:pfam02463  863 ITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLL 942
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  831 QRESSAEklrKMEEKCESAAHEADLKRQKVIELTgtaRQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILD 910
Cdd:pfam02463  943 EEADEKE---KEENNKEEEEERNKRLLLAKEELG---KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
                          810
                   ....*....|...
gi 1034558166  911 QTKTELEKKTNAV 923
Cdd:pfam02463 1017 QRLKEFLELFVSI 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1036-1312 2.77e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 2.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1036 REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLN------DKLQNAKEQLREKEFIMLQNEqeISQLKKEIERTQQRM 1109
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLVLR--LEELREELEELQEEL 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1110 KEMESVMKEQEQYIATqykeaidLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLsselEDMKQLSKEKDAHGNHL 1189
Cdd:TIGR02168  249 KEAEEELEELTAELQE-------LEEKLEELRLEVSELEEEIEELQKELYALANEISRL----EQQKQILRERLANLERQ 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1190 AEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWkisadsqkssvQQLNEQLEKAKLELEEAQD 1269
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL-----------EELESRLEELEEQLETLRS 386
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1034558166 1270 TVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKA 1312
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1041-1224 3.01e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 51.37  E-value: 3.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE 1120
Cdd:COG3883     20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSG 99
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1121 -------------------------QYIATQYKEAID----LGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSE 1171
Cdd:COG3883    100 gsvsyldvllgsesfsdfldrlsalSKIADADADLLEelkaDKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAE 179
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034558166 1172 LED-MKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEA 1224
Cdd:COG3883    180 QEAlLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
909-1121 3.01e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 3.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  909 LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKD 988
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  989 LTAELreCKMEIEDKKQELL---------EMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 1059
Cdd:COG4942    109 LLRAL--YRLGRQPPLALLLspedfldavRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034558166 1060 LKECNKQIESLNDKLQNAKEQLREKEfimlqneQEISQLKKEIERTQQRMKEMESVMKEQEQ 1121
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELA-------AELAELQQEAEELEALIARLEAEAAAAAE 241
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
936-1285 4.39e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.05  E-value: 4.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  936 ELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALK 1015
Cdd:pfam07888   42 ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALL 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1016 ERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR------------- 1082
Cdd:pfam07888  122 AQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRslskefqelrnsl 201
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1083 -EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKE----QEQYIATQYKEAIdLGQELRLTREQVQNSHTELAEARHQ 1157
Cdd:pfam07888  202 aQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEElrslQERLNASERKVEG-LGEELSSMAAQRDRTQAELHQARLQ 280
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1158 QVQAQREIERLSSEL-EDMKQLSKEKDAhgnhLAEELGASKVReahlearmqaeIKKLSAEVESLKEAYHMEMISHQENH 1236
Cdd:pfam07888  281 AAQLTLQLADASLALrEGRARWAQERET----LQQSAEADKDR-----------IEKLSAELQRLEERLQEERMEREKLE 345
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1034558166 1237 AKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVI 1285
Cdd:pfam07888  346 VELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYI 394
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
850-1208 4.46e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 4.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  850 AHEADLKRQKVI----ELTGTARQVKIEMDQYKE---ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTktelEKKTNA 922
Cdd:COG3096    277 ANERRELSERALelrrELFGARRQLAEEQYRLVEmarELEELSARESDLEQDYQAASDHLNLVQTALRQQ----EKIERY 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  923 VKELEKL------QHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQ-------KAQLSLEE--KYTTIK 987
Cdd:COG3096    353 QEDLEELterleeQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqQAVQALEKarALCGLP 432
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAElreckmEIEDKKQELLEMDQALKERNWELKQRAAQVthlDMTIREHRGEMeQKIIKLEGTLEKSelelkecnkqi 1067
Cdd:COG3096    433 DLTPE------NAEDYLAAFRAKEQQATEEVLELEQKLSVA---DAARRQFEKAY-ELVCKIAGEVERS----------- 491
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1068 eslnDKLQNAKEQLRE-KEFIML-QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQ 1145
Cdd:COG3096    492 ----QAWQTARELLRRyRSQQALaQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLE 567
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1146 NSHTELAEARHQQVQAQREIERLSselEDMKQLSK------EKDAHGNHLAEELGASKVREAHLEARMQ 1208
Cdd:COG3096    568 ELEEQAAEAVEQRSELRQQLEQLR---ARIKELAArapawlAAQDALERLREQSGEALADSQEVTAAMQ 633
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
908-1302 4.62e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 4.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  908 ILDQTKTELEKKTNAVKELEklqhstETELTEALQKrevLETELQNAHGELKSTLRQLQELRDVLQKAQLSL---EEKYT 984
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKE------EKDLHERLNG---LESELAELDEEIERYEEQREQARETRDEADEVLeehEERRE 251
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  985 TIKDLTAELRECKMEIEDKKQEllemDQALKERnwelkqraaqvthldmtIREHRGEMEQKIIKLEGTLEKSELELKEcN 1064
Cdd:PRK02224   252 ELETLEAEIEDLRETIAETERE----REELAEE-----------------VRDLRERLEELEEERDDLLAEAGLDDAD-A 309
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1065 KQIESLNDKLQNAKEQLREKefiMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQyiatqykEAIDLGQELRLTREQV 1144
Cdd:PRK02224   310 EAVEARREELEDRDEELRDR---LEECRVAAQAHNEEAESLREDADDLEERAEELRE-------EAAELESELEEAREAV 379
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1145 QNSHTELAEARhqqvqaqREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQaEIKKLSAEVESLKEA 1224
Cdd:PRK02224   380 EDRREEIEELE-------EEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR-TARERVEEAEALLEA 451
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1225 YHMEMISHQenhakwkISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEA--LLTKESELTRL 1302
Cdd:PRK02224   452 GKCPECGQP-------VEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIerLEERREDLEEL 524
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
817-1292 6.71e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 6.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  817 LEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGE 896
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  897 NKAMH--LSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQK 974
Cdd:COG4717    127 LLPLYqeLEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  975 AQLSLEEKYTTIKDLTAELREcKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQK--------- 1045
Cdd:COG4717    207 RLAELEEELEEAQEELEELEE-ELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlflvlgl 285
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1046 IIKLEGTLEKSELELKECNKQIESLN--DKLQNA--KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQ 1121
Cdd:COG4717    286 LALLFLLLAREKASLGKEAEELQALPalEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1122 yiatqykeaIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMkqlskekdahgnhLAEELGASKVR-E 1200
Cdd:COG4717    366 ---------EELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQ-------------LEELLGELEELlE 423
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1201 AHLEARMQAEIKKLSAEVESLKEayHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEE----------AQDT 1270
Cdd:COG4717    424 ALDEEELEEELEELEEELEELEE--ELEELREELAELEAELEQLEEDGELAELLQELEELKAELRElaeewaalklALEL 501
                          490       500
                   ....*....|....*....|....
gi 1034558166 1271 VSNLHQQVQDRN--EVIEAANEAL 1292
Cdd:COG4717    502 LEEAREEYREERlpPVLERASEYF 525
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
936-1304 7.21e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.11  E-value: 7.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  936 ELTEALQKREVLETELQNAHGEL---KSTLRQ----------LQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIED 1002
Cdd:COG3096    314 ELEELSARESDLEQDYQAASDHLnlvQTALRQqekieryqedLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDS 393
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1003 KKQELLEMDQALKErnweLKQRAAQVthldmtirehrgemeQKIIKlegTLEKSELELKECNKQIESLNDKLQNAKEQLR 1082
Cdd:COG3096    394 LKSQLADYQQALDV----QQTRAIQY---------------QQAVQ---ALEKARALCGLPDLTPENAEDYLAAFRAKEQ 451
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1083 EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY-KEAIDLGQELRLTREQVQNSHTELAEARhQQVQA 1161
Cdd:COG3096    452 QATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTaRELLRRYRSQQALAQRLQQLRAQLAELE-QRLRQ 530
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1162 QREIERLSSELEdmKQLSKEKDAhgnhlAEELgaskvreAHLEARMQAEIKKLSAEVESLKEAyHMEMiSHQENHAKWKI 1241
Cdd:COG3096    531 QQNAERLLEEFC--QRIGQQLDA-----AEEL-------EELLAELEAQLEELEEQAAEAVEQ-RSEL-RQQLEQLRARI 594
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1242 SADSQKSSV------------QQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEvIEAANEALltkESELTRLQA 1304
Cdd:COG3096    595 KELAARAPAwlaaqdalerlrEQSGEALADSQEVTAAMQQLLEREREATVERDE-LAARKQAL---ESQIERLSQ 665
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
935-1208 7.60e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 7.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  935 TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKD--------LTAELRECKMEIEDKKQE 1006
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDqwkekrdeLNGELSAADAAVAKDRSE 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1007 LLEMD-QALKERNWELKQRAAQVTHLDmTIREHRGEMEQKIIKLEGTLEKSELELK--------ECNKQIESLNDKLQNA 1077
Cdd:pfam12128  324 LEALEdQHGAFLDADIETAAADQEQLP-SWQSELENLEERLKALTGKHQDVTAKYNrrrskikeQNNRDIAGIKDKLAKI 402
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1078 KEQL-REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELrltrEQVQNSHTELAEARH 1156
Cdd:pfam12128  403 REARdRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELL----LQLENFDERIERARE 478
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1034558166 1157 QQVQAQREIERLSSELEDMKQLSKEKDAHgnHLAEELGASKVREAHLEARMQ 1208
Cdd:pfam12128  479 EQEAANAEVERLQSELRQARKRRDQASEA--LRQASRRLEERQSALDELELQ 528
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
940-1174 7.67e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 7.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  940 ALQKREVLETE---LQNAHGELKSTLRQLQELRDVLQKAQLS---LEEKYTTIKDLTAELRECkMEIEDKKQELLEMDQA 1013
Cdd:COG4913    608 NRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREAlqrLAEYSWDEIDVASAEREI-AELEAELERLDASSDD 686
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1014 LKernwELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQ 1093
Cdd:COG4913    687 LA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1094 EISQLKKEIERTQQRMKEM-----ESVMKEQEQYIATQYKEAIDLGQELRlTREQVQNSHTELAE---ARHQQ------- 1158
Cdd:COG4913    763 VERELRENLEERIDALRARlnraeEELERAMRAFNREWPAETADLDADLE-SLPEYLALLDRLEEdglPEYEErfkelln 841
                          250
                   ....*....|....*.
gi 1034558166 1159 VQAQREIERLSSELED 1174
Cdd:COG4913    842 ENSIEFVADLLSKLRR 857
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
232-1070 8.10e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.74  E-value: 8.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  232 KRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTnCEKENKRLQERCGLYKSELEILKEKLRQLKEE 311
Cdd:pfam02463  181 ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLL-YLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  312 NNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVE 391
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  392 LRSLEKIISQLPLKRELfgFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIK---LAIKEAEIQKLHANLTANQLS 468
Cdd:pfam02463  340 LEKELKELEIKREAEEE--EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeeeLELKSEEEKEAQLLLELARQL 417
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  469 QSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAH 548
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  549 RTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHE 628
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  629 KICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKK 708
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG 657
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  709 DEALKALQNQVSEETIkvRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVI 788
Cdd:pfam02463  658 LAEKSEVKASLSELTK--ELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  789 LQHTLQQQQQMLQQEtirngELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTAR 868
Cdd:pfam02463  736 EELKLLKQKIDEEEE-----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  869 QVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKEL--EKLQHSTETELTEALQKREV 946
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELlqELLLKEEELEEQKLKDELES 890
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  947 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAA 1026
Cdd:pfam02463  891 KEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1034558166 1027 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL 1070
Cdd:pfam02463  971 ELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
563-1223 8.26e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.74  E-value: 8.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  563 KASNSSKLESEMTKKCSQLLTLEkqLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKI--CLAFEKAKKI 640
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLC--TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQeeQLKKQQLLKQ 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  641 HLEQHKEMEKQIERLEAQLEKKDQQFKEQEktmsmlqqdIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVS 720
Cdd:TIGR00618  265 LRARIEELRAQEAVLEETQERINRARKAAP---------LAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVK 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  721 EEtikvrqldSALEICKEELVLHLNQLEGNKEKFEKQLKKKseEVYCLQKELKIKNHSLQETSEqnvilqhTLQQQQQML 800
Cdd:TIGR00618  336 QQ--------SSIEEQRRLLQTLHSQEIHIRDAHEVATSIR--EISCQQHTLTQHIHTLQQQKT-------TLTQKLQSL 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  801 QQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK--IEMDQYK 878
Cdd:TIGR00618  399 CKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKerEQQLQTK 478
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  879 EELSKMEKEImhlKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQhsteTELTEALQKREVLETELQNAHGEL 958
Cdd:TIGR00618  479 EQIHLQETRK---KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT----RRMQRGEQTYAQLETSEEDVYHQL 551
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  959 KSTLRQLQELRDVLQKAQ---LSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHlDMTI 1035
Cdd:TIGR00618  552 TSERKQRASLKEQMQEIQqsfSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD-LQDV 630
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1036 REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNA-KEQLREKEFIMLQNE-QEISQLKKEIERTQQRMKEME 1113
Cdd:TIGR00618  631 RLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKeLLASRQLALQKMQSEkEQLTYWKEMLAQCQTLLRELE 710
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1114 SVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMkqlskekdahgnhlAEEL 1193
Cdd:TIGR00618  711 THIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA--------------ALQT 776
                          650       660       670
                   ....*....|....*....|....*....|
gi 1034558166 1194 GAskvREAHLEARMQAEIKKLSAEVESLKE 1223
Cdd:TIGR00618  777 GA---ELSHLAAEIQFFNRLREEDTHLLKT 803
PRK01156 PRK01156
chromosome segregation protein; Provisional
565-1113 1.26e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.90  E-value: 1.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  565 SNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIrsleTNINTEHEKICLAFEKAKKIHLEQ 644
Cdd:PRK01156   183 SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDY----NNLKSALNELSSLEDMKNRYESEI 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  645 hkemeKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHH-----------LESLDRLLTESKGEMKK--ENMKKDEA 711
Cdd:PRK01156   259 -----KTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNyindyfkykndIENKKQILSNIDAEINKyhAIIKKLSV 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  712 LKALQNQVSEETIKvrqldsaleicKEELVLHLNQLEGNKEKFEKQLKKKSeevyclQKELKIKNHSLQETSEQNVILQH 791
Cdd:PRK01156   334 LQKDYNDYIKKKSR-----------YDDLNNQILELEGYEMDYNSYLKSIE------SLKKKIEEYSKNIERMSAFISEI 396
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  792 TLQQQQQMLQQETIRNgELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEkcesaaheadLKRQKVIELTGT---AR 868
Cdd:PRK01156   397 LKIQEIDPDAIKKELN-EINVKLQDISSKVSSLNQRIRALRENLDELSRNMEM----------LNGQSVCPVCGTtlgEE 465
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  869 QVKIEMDQYKEELSKMEKEIMHLKRDG---ENKAMHLSQLDMILDqtKTELEKKTNAVKELEKLQHS------TETELTE 939
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEKIREIEIEVkdiDEKIVDLKKRKEYLE--SEEINKSINEYNKIESARADledikiKINELKD 543
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  940 ALQKREVLETELQNAH-GELKSTLRQLQELRDV-----LQKAQLSLEEKYTTIKDLTAELRECKMEIEDKK-------QE 1006
Cdd:PRK01156   544 KHDKYEEIKNRYKSLKlEDLDSKRTSWLNALAVislidIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyidksiRE 623
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1007 LLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQK--IIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREK 1084
Cdd:PRK01156   624 IENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIdsIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLEST 703
                          570       580
                   ....*....|....*....|....*....
gi 1034558166 1085 EFIMLQNEQEISQLKKEIERTQQRMKEME 1113
Cdd:PRK01156   704 IEILRTRINELSDRINDINETLESMKKIK 732
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
751-1041 1.93e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.09  E-value: 1.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  751 KEKFEKQLKKKSEEVyclqKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK 830
Cdd:COG2433    349 KNKFERVEKKVPPDV----DRDEVKARVIRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER 424
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  831 QRESSAEKLRKMEEKCESAAH-EADLKRqkvieltgtARQVKIEMDQYKEELSKMEKEIMHLKRDgenkamhLSQLDMIL 909
Cdd:COG2433    425 LEAEVEELEAELEEKDERIERlERELSE---------ARSEERREIRKDREISRLDREIERLERE-------LEEERERI 488
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  910 DqtktELEKKTNAVKELEKLQHSTETELT---EALQKREVLETE------------LQNAHGELKSTLRQLQEL--RDVL 972
Cdd:COG2433    489 E----ELKRKLERLKELWKLEHSGELVPVkvvEKFTKEAIRRLEeeyglkegdvvyLRDASGAGRSTAELLAEAgpRAVI 564
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166  973 QKAQLSlEEKYTTIKDLT-AELRECKMEIEDK------KQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 1041
Cdd:COG2433    565 VPGELS-EAADEVLFEEGiPVLPAEDVTIQEVddlavvDEEELEAAIEDWEERAEERRREKKAEMLERLISEYRAE 639
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
147-937 2.05e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  147 ELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLE 226
Cdd:pfam02463  220 ELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK 299
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  227 QTK-QGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKL 305
Cdd:pfam02463  300 SELlKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  306 RQLKEENNNGKEKLRIMA------VKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLD 379
Cdd:pfam02463  380 KLESERLSSAAKLKEEELelkseeEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELK 459
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  380 LCQQEIESSRVELRSLEKIISQLPLKRELfgfksYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLH 459
Cdd:pfam02463  460 LLKDELELKKSEDLLKETQLVKLQEQLEL-----LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDL 534
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  460 ANLTANQLSQSLITCND------SQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLI 533
Cdd:pfam02463  535 GVAVENYKVAISTAVIVevsataDEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE 614
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  534 QIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYsSIAAKNAELEQELMEKN 613
Cdd:pfam02463  615 ADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL-EIQELQEKAESELAKEE 693
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  614 EKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIE-RLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDR 692
Cdd:pfam02463  694 ILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKiNEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKE 773
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  693 LLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKEL 772
Cdd:pfam02463  774 KELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAE 853
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  773 KIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHE 852
Cdd:pfam02463  854 EELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKY 933
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  853 ADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHS 932
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIE 1013

                   ....*
gi 1034558166  933 TETEL 937
Cdd:pfam02463 1014 ETCQR 1018
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
909-1113 2.07e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.24  E-value: 2.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  909 LDQTKTELEKKTNAVKELeKLQH---STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEkyTT 985
Cdd:COG3206    184 LPELRKELEEAEAALEEF-RQKNglvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPE--LL 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  986 IKDLTAELREckmEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREhrgEMEQKIIKLEGTLEKSELELKECNK 1065
Cdd:COG3206    261 QSPVIQQLRA---QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ---EAQRILASLEAELEALQAREASLQA 334
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1034558166 1066 QIESLNDKLQNAKEQlrEKEFIMLQNEQEISQlkKEIERTQQRMKEME 1113
Cdd:COG3206    335 QLAQLEARLAELPEL--EAELRRLEREVEVAR--ELYESLLQRLEEAR 378
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
710-1113 2.31e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  710 EALKALQNQVSEETIKVRQLdsaleickEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL 789
Cdd:COG4717     71 KELKELEEELKEAEEKEEEY--------AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELA 142
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  790 QHTLQQQQQMLQQETIRngELEDTQTKLEKQVSKLEQEL----QKQRESSAEKLRKMEEKCESAaheadlkRQKVIELTG 865
Cdd:COG4717    143 ELPERLEELEERLEELR--ELEEELEELEAELAELQEELeellEQLSLATEEELQDLAEELEEL-------QQRLAELEE 213
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  866 TARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM------------------------------------IL 909
Cdd:COG4717    214 ELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglggsllsliltiagvlflvlgllallflLL 293
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  910 DQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYtTIKDL 989
Cdd:COG4717    294 AREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEE-LEQEI 372
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  990 TAELRECKMEIEDKKQELLEMDQalkernwELKQRAAQVTHLDMTIREHRGEMEQKIikLEGTLEKSELELKECNKQIES 1069
Cdd:COG4717    373 AALLAEAGVEDEEELRAALEQAE-------EYQELKEELEELEEQLEELLGELEELL--EALDEEELEEELEELEEELEE 443
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1070 LNDKLQNAKEQLREKEFIM--LQNEQEISQLKKEIERTQQRMKEME 1113
Cdd:COG4717    444 LEEELEELREELAELEAELeqLEEDGELAELLQELEELKAELRELA 489
PRK12704 PRK12704
phosphodiesterase; Provisional
170-348 2.35e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 48.62  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  170 ILEEQIINLEAEVsaqDKVLREAENKLEQsqkmviEKEQSLQESKEECIKLKvdlleqtkqgkraerqrnealynaEELS 249
Cdd:PRK12704    28 IAEAKIKEAEEEA---KRILEEAKKEAEA------IKKEALLEAKEEIHKLR------------------------NEFE 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  250 KAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLrimavknsEV 329
Cdd:PRK12704    75 KELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL--------ER 146
                          170       180
                   ....*....|....*....|..
gi 1034558166  330 MAQLT--ESRQSIL-KLESELE 348
Cdd:PRK12704   147 ISGLTaeEAKEILLeKVEEEAR 168
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
586-1045 2.64e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 2.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  586 KQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTehekicLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ 665
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEE------LREELEKLEKLLQLLPLYQELEALEAELAELPER 147
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  666 FKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEElvlhLN 745
Cdd:COG4717    148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE----LE 223
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  746 QLEGNKEKFEKQLkkkseEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQE---TIRNGELEDTQTKLEKQVS 822
Cdd:COG4717    224 ELEEELEQLENEL-----EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlFLVLGLLALLFLLLAREKA 298
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  823 KLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKiEMDQYKEELSKMEKEIMHLKRDGENKAMhl 902
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEELEEELQLEELEQEIAAL-- 375
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  903 sqLDMILDQTKTELEKKTNAVKELEKLQhsteteltealQKREVLETELQNAHGELKSTLRQLQ--ELRDVLQKAQLSLE 980
Cdd:COG4717    376 --LAEAGVEDEEELRAALEQAEEYQELK-----------EELEELEEQLEELLGELEELLEALDeeELEEELEELEEELE 442
                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  981 EKYTTIKDLTAELRECKMEIE-----DKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQK 1045
Cdd:COG4717    443 ELEEELEELREELAELEAELEqleedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
1041-1193 2.72e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.23  E-value: 2.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRM------KEMES 1114
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnKEYEA 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1115 VMKEqeqyIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELE--------DMKQLSKEKDAHG 1186
Cdd:COG1579     94 LQKE----IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDeelaeleaELEELEAEREELA 169

                   ....*..
gi 1034558166 1187 NHLAEEL 1193
Cdd:COG1579    170 AKIPPEL 176
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
947-1119 2.77e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.23  E-value: 2.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  947 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE--RNWELKQR 1024
Cdd:COG1579     15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEAL 94
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1025 AAQVTHLdmtiREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREkefimlqneqEISQLKKEIER 1104
Cdd:COG1579     95 QKEIESL----KRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE----------ELAELEAELEE 160
                          170
                   ....*....|....*
gi 1034558166 1105 TQQRMKEMESVMKEQ 1119
Cdd:COG1579    161 LEAEREELAAKIPPE 175
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
814-1027 2.89e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 2.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  814 QTKLEKQVSKLeQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKR 893
Cdd:COG3883     15 DPQIQAKQKEL-SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  894 DGENKAMHLSQLDMILDQTK-TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVL 972
Cdd:COG3883     94 ALYRSGGSVSYLDVLLGSESfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166  973 QKAQlslEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQ 1027
Cdd:COG3883    174 EAQQ---AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1036-1133 3.95e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 48.32  E-value: 3.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1036 REHRGEMEQKIIKLEGTLEK-----SEL--ELKECNKQIESLNDKLQNAKEQLREKefimLQNEQEISQLKKEIERTQQR 1108
Cdd:COG2433    405 ERELTEEEEEIRRLEEQVERleaevEELeaELEEKDERIERLERELSEARSEERRE----IRKDREISRLDREIERLERE 480
                           90       100
                   ....*....|....*....|....*
gi 1034558166 1109 MKEMESVMKEQEQYIAtQYKEAIDL 1133
Cdd:COG2433    481 LEEERERIEELKRKLE-RLKELWKL 504
46 PHA02562
endonuclease subunit; Provisional
939-1143 5.11e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 5.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTtikDLTAELRECKMEIEDKKQELLEMDQALKERN 1018
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD---ELVEEAKTIKAEIEELTDELLNLVMDIEDPS 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1019 WELKQRAAQVTHLDMTIREHRGEME------------QKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEqlREKEF 1086
Cdd:PHA02562   255 AALNKLNTAAAKIKSKIEQFQKVIKmyekggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEE--IMDEF 332
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034558166 1087 IMLQNEQ-----EISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQ 1143
Cdd:PHA02562   333 NEQSKKLlelknKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1064-1225 6.30e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 6.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1064 NKQIESLNDKLQNAKEQL----REKEFIMLQNE-----QEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLG 1134
Cdd:COG3206    181 EEQLPELRKELEEAEAALeefrQKNGLVDLSEEaklllQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1135 Q--ELRLTREQVQNSHTELAEAR------HQQVQA-QREIERLSSELED-MKQLSKEKDAHGNHLAEELGASKVREAHLE 1204
Cdd:COG3206    261 QspVIQQLRAQLAELEAELAELSarytpnHPDVIAlRAQIAALRAQLQQeAQRILASLEAELEALQAREASLQAQLAQLE 340
                          170       180
                   ....*....|....*....|....*..
gi 1034558166 1205 ARM------QAEIKKLSAEVESLKEAY 1225
Cdd:COG3206    341 ARLaelpelEAELRRLEREVEVARELY 367
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
967-1291 6.34e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 6.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  967 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKqELLEMDQALKERNWELKQRAAQVTHldmTIREHRGEMEQKI 1046
Cdd:PRK03918   145 ESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLE-KFIKRTENIEELIKEKEKELEEVLR---EINEISSELPELR 220
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1047 IKLEGtLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIAtq 1126
Cdd:PRK03918   221 EELEK-LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK-- 297
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1127 ykeaidLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDahgnHLAEELGASKVREAHLEar 1206
Cdd:PRK03918   298 ------LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK----ELEKRLEELEERHELYE-- 365
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1207 mqaEIKKLSAEVESLKeayhmemishqenhakwKISADSQKSSVQQLNEQLEKAKLELEEAQDTV----SNLHQQVQDRN 1282
Cdd:PRK03918   366 ---EAKAKKEELERLK-----------------KRLTGLTPEKLEKELEELEKAKEEIEEEISKItariGELKKEIKELK 425

                   ....*....
gi 1034558166 1283 EVIEAANEA 1291
Cdd:PRK03918   426 KAIEELKKA 434
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
807-1152 6.61e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 6.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  807 NGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEK 886
Cdd:pfam12128  631 NGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKR 710
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  887 EimHLKRDGENKAMHLSQLDMILDQTKTELEK-KTNAVKELEKLQHSTETELtEALQKREVLETELQNAHGELKSTLRQL 965
Cdd:pfam12128  711 E--ARTEKQAYWQVVEGALDAQLALLKAAIAArRSGAKAELKALETWYKRDL-ASLGVDPDVIAKLKREIRTLERKIERI 787
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  966 QELRDVLQKAQLSLEEKYTTIKD-LTAELRECKMEIEDKKQELLEMDQALKERNWEL-KQRAA---QVTHLDMTIREHRG 1040
Cdd:pfam12128  788 AVRRQEVLRYFDWYQETWLQRRPrLATQLSNIERAISELQQQLARLIADTKLRRAKLeMERKAsekQQVRLSENLRGLRC 867
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQ-KIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKefimlqNEQEISQLKK----EIERTQQRMKEMESV 1115
Cdd:pfam12128  868 EMSKlATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKY------VEHFKNVIADhsgsGLAETWESLREEDHY 941
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1034558166 1116 MKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELA 1152
Cdd:pfam12128  942 QNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQV 978
PTZ00121 PTZ00121
MAEBL; Provisional
499-1011 8.10e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 8.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  499 AESVKDQNQHTMNKQYEKERQRLVTGIEELRTKL--IQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTK 576
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAdaAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  577 KCSQllTLEKQLEEKIVAYSsiAAKNAEleqELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLE 656
Cdd:PTZ00121  1378 KKAD--AAKKKAEEKKKADE--AKKKAE---EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  657 AQLEKKDQQFKEQEKTMSMLQQDIICKQHHLEsldRLLTESKGEMKKENMKKDEALKALQ-NQVSEETIKVRQLDSALEI 735
Cdd:PTZ00121  1451 KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA---KKADEAKKKAEEAKKKADEAKKAAEaKKKADEAKKAEEAKKADEA 1527
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  736 CKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQT 815
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  816 KLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEadlKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDG 895
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE---EKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  896 ENKAMHLSQLdmildQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA 975
Cdd:PTZ00121  1685 EDEKKAAEAL-----KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759
                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1034558166  976 QLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMD 1011
Cdd:PTZ00121  1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795
PRK11281 PRK11281
mechanosensitive channel MscK;
939-1180 8.89e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 8.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETELQNAHGELKSTLRQLqelrDVLQKAQLSLEEKYTTIKDLTAELRECKMEIED-KKQELLEMDQAL-KE 1016
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlKDDNDEETRETLsTL 121
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1017 RNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQN---AKEQLREKEFIMLQNEQ 1093
Cdd:PRK11281   122 SLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGgkvGGKALRPSQRVLLQAEQ 201
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1094 -----EISQLKKEIERTQQrmkeMESVMKEQEQYIAtqykEAID-LGQELRLTREQVQNSHTELAEARHQQVQAQREIER 1167
Cdd:PRK11281   202 allnaQNDLQRKSLEGNTQ----LQDLLQKQRDYLT----ARIQrLEHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAAR 273
                          250
                   ....*....|....*....
gi 1034558166 1168 ------LSSELEDMKQLSK 1180
Cdd:PRK11281   274 iqanplVAQELEINLQLSQ 292
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
829-1153 1.04e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  829 QKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEmdqyKEELSKMEKEIMHLKRDGENKAMHLSQLDMI 908
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMD----RQAAIYAEQERMAMERERELERIRQEERKRE 361
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  909 LDQTKT-ELEKKTNAVKELEKLQhstetelTEALQKREVLETELQNAhgelkstlrqlqelrdvlQKAQLSLEEKYTTIK 987
Cdd:pfam17380  362 LERIRQeEIAMEISRMRELERLQ-------MERQQKNERVRQELEAA------------------RKVKILEEERQRKIQ 416
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAELRECKMEIEDKKQELLEMDQALKERNWE-LKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQ 1066
Cdd:pfam17380  417 QQKVEMEQIRAEQEEARQREVRRLEEERAREMErVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKI 496
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1067 IESLNDKLQNA------KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQY-IATQYKEAIDLGQELRL 1139
Cdd:pfam17380  497 LEKELEERKQAmieeerKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMrKATEERSRLEAMERERE 576
                          330
                   ....*....|....
gi 1034558166 1140 TREQVQNSHTELAE 1153
Cdd:pfam17380  577 MMRQIVESEKARAE 590
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
328-979 1.30e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 46.67  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  328 EVMAQLTESRQSILKLESELENKDEILRdkfSLMNENRELKVRVAAQNERLDLC-------QQEIESSRVELRSLEKIIS 400
Cdd:pfam07111   56 EGSQALSQQAELISRQLQELRRLEEEVR---LLRETSLQQKMRLEAQAMELDALavaekagQAEAEGLRAALAGAEMVRK 132
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  401 QLP--LKRELFGFKSyLSKYQMSSFSNKEDRCIGC----CEANKLVISELRIKLA--IKEAEIQKLHANLTANQLSQSli 472
Cdd:pfam07111  133 NLEegSQRELEEIQR-LHQEQLSSLTQAHEEALSSltskAEGLEKSLNSLETKRAgeAKQLAEAQKEAELLRKQLSKT-- 209
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  473 tcndSQESSKLSSLETEPVKLGGHQVAESVKDQnqhtmnkQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQ 552
Cdd:pfam07111  210 ----QEELEAQVTLVESLRKYVGEQVPPEVHSQ-------TWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHM 278
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  553 FQLIQEELLEKASNSSKLESEMTKKCSQLLtleKQLEEKIVAYSsiaaknAELEQELMEKNEKIRSLETNINTEHEKI-C 631
Cdd:pfam07111  279 LALQEEELTRKIQPSDSLEPEFPKKCRSLL---NRWREKVFALM------VQLKAQDLEHRDSVKQLRGQVAELQEQVtS 349
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  632 LAFEKAKKIHLEQHKEMEKQIERLEAQleKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEA 711
Cdd:pfam07111  350 QSQEQAILQRALQDKAAEVEVERMSAK--GLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQA 427
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  712 LKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN---------KEKFEKQLKKKSEEVYCLQKELKIKNHSLQEt 782
Cdd:pfam07111  428 VARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRQESCpppppappvDADLSLELEQLREERNRLDAELQLSAHLIQQ- 506
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  783 seqnvilqhtlqqqqqmLQQETIRNGELEDTQtkLEKQVSKLEQELQKQRESSA---EKLRKMEEKCESAAHEADLKRQK 859
Cdd:pfam07111  507 -----------------EVGRAREQGEAERQQ--LSEVAQQLEQELQRAQESLAsvgQQLEVARQGQQESTEEAASLRQE 567
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  860 VI---ELTGTARQVKIE--MDQYKEELSKMEKEIMHLKRDGENKAMHLSQLdmildQTKTELEKKTNavKELEKLQHSTE 934
Cdd:pfam07111  568 LTqqqEIYGQALQEKVAevETRLREQLSDTKRRLNEARREQAKAVVSLRQI-----QHRATQEKERN--QELRRLQDEAR 640
                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1034558166  935 TELTEALQKRevlETELQNAHGELKSTLRQLQELRDVLQKAQLSL 979
Cdd:pfam07111  641 KEEGQRLARR---VQELERDKNLMLATLQQEGLLSRYKQQRLLAV 682
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
809-1195 1.48e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  809 ELEDTQTKLEKQVSKLEqELQKQRESSAEKLRKMEEKCESAAHE-ADLkrQKVIELTGTaRQVkiemdQYKEELSKMEKE 887
Cdd:COG3096    355 DLEELTERLEEQEEVVE-EAAEQLAEAEARLEAAEEEVDSLKSQlADY--QQALDVQQT-RAI-----QYQQAVQALEKA 425
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  888 imhlKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELE-KLQHSTE--TELTEALQ--KREVLETELQNAHGELKSTL 962
Cdd:COG3096    426 ----RALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEqKLSVADAarRQFEKAYElvCKIAGEVERSQAWQTARELL 501
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  963 RQLQELRDVLQKAQlSLEEKYttikdltAELREcKMEIEDKKQELLEmdqalkernwELKQRAAQVTHLDMTIREHRGEM 1042
Cdd:COG3096    502 RRYRSQQALAQRLQ-QLRAQL-------AELEQ-RLRQQQNAERLLE----------EFCQRIGQQLDAAEELEELLAEL 562
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1043 EQkiiklegtlekselelkecnkQIESLNDKLQNAKEQLrekefimlqneqeiSQLKKEIERTQQRMKEMES------VM 1116
Cdd:COG3096    563 EA---------------------QLEELEEQAAEAVEQR--------------SELRQQLEQLRARIKELAArapawlAA 607
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166 1117 KEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARhQQVQAQREieRLSSELEDMKQLSKEKDAHGNHLAEELGA 1195
Cdd:COG3096    608 QDALERLREQSGEALADSQEVTAAMQQLLEREREATVER-DELAARKQ--ALESQIERLSQPGGAEDPRLLALAERLGG 683
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
438-1299 1.62e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  438 KLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPvklgghqvaesvkdQNQHTMNKQYEKE 517
Cdd:pfam01576  228 QAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDL--------------ESERAARNKAEKQ 293
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  518 RQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLL-TLEKQLEEKIVAYS 596
Cdd:pfam01576  294 RRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALeELTEQLEQAKRNKA 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  597 SIAAKNAELEQELMEKNEKIRSLETnintehekiclafekakkihleQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSML 676
Cdd:pfam01576  374 NLEKAKQALESENAELQAELRTLQQ----------------------AKQDSEHKRKKLEGQLQELQARLSESERQRAEL 431
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  677 QQDIICKQHHLESLDRLLTESKGE---MKKENMKKDEALKALQNQVSEETIKVRQLDS---ALEICKEELVLHLNQLEGN 750
Cdd:pfam01576  432 AEKLSKLQSELESVSSLLNEAEGKnikLSKDVSSLESQLQDTQELLQEETRQKLNLSTrlrQLEDERNSLQEQLEEEEEA 511
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  751 KEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK 830
Cdd:pfam01576  512 KRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDH 591
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  831 QRE--SSAEKLRKMEEKCESAAHEADLKRQKvieltgtarqvkiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMI 908
Cdd:pfam01576  592 QRQlvSNLEKKQKKFDQMLAEEKAISARYAE-------------ERDRAEAEAREKETRALSLARALEEALEAKEELERT 658
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  909 LDQTKTELEKKTNA-------VKELEKLQHSTETELTEALQKREVLETELQ---NAHGELKSTLRQL--QELRDVLQKAQ 976
Cdd:pfam01576  659 NKQLRAEMEDLVSSkddvgknVHELERSKRALEQQVEEMKTQLEELEDELQateDAKLRLEVNMQALkaQFERDLQARDE 738
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  977 LSLEEKyttiKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVThldmTIREHRGEMEQKIIKLEGTLEKS 1056
Cdd:pfam01576  739 QGEEKR----RQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID----AANKGREEAVKQLKKLQAQMKDL 810
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1057 ELEL--------------KECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIER-------TQQRMKEMESV 1115
Cdd:pfam01576  811 QRELeearasrdeilaqsKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASgasgksaLQDEKRRLEAR 890
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1116 MKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEAR-------HQQVQAQREIERLSSELEDMKQLSKEKDAHGNH 1188
Cdd:pfam01576  891 IAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERstsqkseSARQQLERQNKELKAKLQEMEGTVKSKFKSSIA 970
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1189 LAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQ 1268
Cdd:pfam01576  971 ALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRAN 1050
                          890       900       910
                   ....*....|....*....|....*....|.
gi 1034558166 1269 DTVSNLHQQVQDRNEVIEAANEALLTKESEL 1299
Cdd:pfam01576 1051 AARRKLQRELDDATESNESMNREVSTLKSKL 1081
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
1101-1305 2.60e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1101 EIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSK 1180
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1181 EKDAHGNHLAEELGASKVREA--------HLEARMQAEIKKLSAEVESLKEAyhmemishqenhakwKISADSQKSSVQQ 1252
Cdd:COG3883     97 RSGGSVSYLDVLLGSESFSDFldrlsalsKIADADADLLEELKADKAELEAK---------------KAELEAKLAELEA 161
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034558166 1253 LNEQLEKAKLELE----EAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAK 1305
Cdd:COG3883    162 LKAELEAAKAELEaqqaEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
180-420 2.70e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  180 AEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKV 259
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  260 AEKLEKVQAEEEILERNLTNCEKENK--------------RLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVK 325
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRLGRqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  326 NSEVMAQLTESRQSILKLESELENKDEILrdkfslmnenRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLK 405
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLL----------ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
                          250
                   ....*....|....*
gi 1034558166  406 RELFGFKSYLSKYQM 420
Cdd:COG4942    243 TPAAGFAALKGKLPW 257
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
778-1178 3.84e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 3.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  778 SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQREssaeKLRKMEEKCESAAHEADlkr 857
Cdd:pfam07888   39 CLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSRE----KHEELEEKYKELSASSE--- 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  858 qkvieltgtarqvkiEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMildQTKTELEKKTNAVKELEKLQHSTETEl 937
Cdd:pfam07888  112 ---------------ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVL---ERETELERMKERAKKAGAQRKEEEAE- 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  938 tealqkREVLETELQNAHGELKSTLRQLQELRDvlqkaqlSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER 1017
Cdd:pfam07888  173 ------RKQLQAKLQQTEEELRSLSKEFQELRN-------SLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEEL 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1018 NwELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQeisQ 1097
Cdd:pfam07888  240 R-SLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAE---A 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1098 LKKEIERTQQRMKEMESVMKEQEqyiATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSE----LE 1173
Cdd:pfam07888  316 DKDRIEKLSAELQRLEERLQEER---MEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEkqelLE 392

                   ....*
gi 1034558166 1174 DMKQL 1178
Cdd:pfam07888  393 YIRQL 397
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
599-836 3.96e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 3.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  599 AAKNAELEQELMEKNEKIRSLETNINTEhekiclafEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQ 678
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAAL--------KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  679 DIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICK---EELVLHLNQLEGNKEKFE 755
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARReqaEELRADLAELAALRAELE 170
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  756 KQLKKKSEevycLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETirnGELEDTQTKLEKQVSKLEQELQKQRESS 835
Cdd:COG4942    171 AERAELEA----LLAELEEERAALEALKAERQKLLARLEKELAELAAEL---AELQQEAEELEALIARLEAEAAAAAERT 243

                   .
gi 1034558166  836 A 836
Cdd:COG4942    244 P 244
mukB PRK04863
chromosome partition protein MukB;
988-1304 3.99e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 3.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAELRECKMEIEDKKQELLEMDQ---ALKERNWELKQRAAQvthldmtIREHRGEMeQKIIKLEGTLEKSELELKECN 1064
Cdd:PRK04863   290 ELRRELYTSRRQLAAEQYRLVEMARelaELNEAESDLEQDYQA-------ASDHLNLV-QTALRQQEKIERYQADLEELE 361
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1065 KQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMkemesvmkEQEQYIATQYKEAIdlgQELRLTREQV 1144
Cdd:PRK04863   362 ERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQAL--------DVQQTRAIQYQQAV---QALERAKQLC 430
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1145 QNSHTELAEARHQQVQAQREIERLSSELEDMKQ-LSKEKDAHGNH-----LAEELGASKVR-EAHLEA----RMQAEIKK 1213
Cdd:PRK04863   431 GLPDLTADNAEDWLEEFQAKEQEATEELLSLEQkLSVAQAAHSQFeqayqLVRKIAGEVSRsEAWDVArellRRLREQRH 510
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1214 LSAEVESLKEAYH-MEMISHQENHAKWKISADSQKSSVQ------------QLNEQLEKAKLELEEAQDTVSNLHQQVQD 1280
Cdd:PRK04863   511 LAEQLQQLRMRLSeLEQRLRQQQRAERLLAEFCKRLGKNlddedeleqlqeELEARLESLSESVSEARERRMALRQQLEQ 590
                          330       340
                   ....*....|....*....|....*..
gi 1034558166 1281 RNEVI---EAANEALLTKESELTRLQA 1304
Cdd:PRK04863   591 LQARIqrlAARAPAWLAAQDALARLRE 617
mukB PRK04863
chromosome partition protein MukB;
832-1186 4.20e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 4.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  832 RESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQ-------VKIEMDQyKEELSKMEKEIMHLKRdgenkamHLSQ 904
Cdd:PRK04863   784 REKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRfigshlaVAFEADP-EAELRQLNRRRVELER-------ALAD 855
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  905 LDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKR-EVLETELQNAHgELKSTLRQlqelrdvlQKAQLSLEEKy 983
Cdd:PRK04863   856 HESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRvEEIREQLDEAE-EAKRFVQQ--------HGNALAQLEP- 925
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  984 ttikdLTAELRECKMEIEDKKQELLEMDQALKErnweLKQRAAQVTHLdMTIREHRG-EMEQKIikLEGTLEKSELeLKE 1062
Cdd:PRK04863   926 -----IVSVLQSDPEQFEQLKQDYQQAQQTQRD----AKQQAFALTEV-VQRRAHFSyEDAAEM--LAKNSDLNEK-LRQ 992
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1063 CNKQIESLNDKlqnAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEqeqyIATQYKEaiDLGQELRLTRE 1142
Cdd:PRK04863   993 RLEQAEQERTR---AREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQD----LGVPADS--GAEERARARRD 1063
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1143 QVqnsHTELAEARHQQVQAQREIERLSSELEDM-KQLSK-EKDAHG 1186
Cdd:PRK04863  1064 EL---HARLSANRSRRNQLEKQLTFCEAEMDNLtKKLRKlERDYHE 1106
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
187-784 4.37e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 4.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  187 KVLREAENKLEQsqkmvIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALynAEELSKAFQQYK--KKVAEKLE 264
Cdd:PRK03918   169 EVIKEIKRRIER-----LEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL--REELEKLEKEVKelEELKEEIE 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  265 KVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRImavknSEVMAQLTESRQSILKLE 344
Cdd:PRK03918   242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKL-----SEFYEEYLDELREIEKRL 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  345 SELENKDEILRDKfslMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIisqLPLKRELFGFKSYLSKYQMSSFS 424
Cdd:PRK03918   317 SRLEEEINGIEER---IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEA---KAKKEELERLKKRLTGLTPEKLE 390
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  425 NKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQ-------LSQSLITCNDSQESSKLSSLETEPVKLGGHQ 497
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpVCGRELTEEHRKELLEEYTAELKRIEKELKE 470
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  498 VAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVnmahrtsqfqliqEELLEKASNSSKLESEMTKK 577
Cdd:PRK03918   471 IEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL-------------EELEKKAEEYEKLKEKLIKL 537
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  578 CSQLLTLEKQLEEKIVAYSSIAA---KNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQhKEMEKQIER 654
Cdd:PRK03918   538 KGEIKSLKKELEKLEELKKKLAElekKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL-KDAEKELER 616
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  655 LEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGE-MKKENMKKDEALKALQNQVSEETIKVRQLDSAL 733
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEeLREEYLELSRELAGLRAELEELEKRREEIKKTL 696
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166  734 EICKEElvlhLNQLEGNKEKFEKqLKKKSEEVYCLQKELK-----IKNHSLQETSE 784
Cdd:PRK03918   697 EKLKEE----LEEREKAKKELEK-LEKALERVEELREKVKkykalLKERALSKVGE 747
mukB PRK04863
chromosome partition protein MukB;
808-1108 4.49e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 4.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  808 GELEDTQTKLEKQVSKLEqELQKQRESSAEKLRKMEEKCESAAHE-ADLKR------------QKVIELTGTARQVKIEM 874
Cdd:PRK04863   355 ADLEELEERLEEQNEVVE-EADEQQEENEARAEAAEEEVDELKSQlADYQQaldvqqtraiqyQQAVQALERAKQLCGLP 433
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  875 D-------QYKEELSKMEKEIMHLKRDGENKamhLSQLDMILDQTKTELEKKTNAVKELEKLQ-HSTETELTEALQKREV 946
Cdd:PRK04863   434 DltadnaeDWLEEFQAKEQEATEELLSLEQK---LSVAQAAHSQFEQAYQLVRKIAGEVSRSEaWDVARELLRRLREQRH 510
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  947 LETELQ---NAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQ 1023
Cdd:PRK04863   511 LAEQLQqlrMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQ 590
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1024 RAAQVTHLDMTirehrgemEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIE 1103
Cdd:PRK04863   591 LQARIQRLAAR--------APAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIE 662

                   ....*
gi 1034558166 1104 RTQQR 1108
Cdd:PRK04863   663 RLSQP 667
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
222-1230 5.49e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.65  E-value: 5.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  222 VDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERcglyKSELEIL 301
Cdd:TIGR00606  185 IKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNR----LKEIEHN 260
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  302 KEKLRQLKEENNNGKEKLRIMAVKNSEVMaqltesrqsiLKLESELENKDEILRDkfslMNENRELKVRvaAQNERLDLC 381
Cdd:TIGR00606  261 LSKIMKLDNEIKALKSRKKQMEKDNSELE----------LKMEKVFQGTDEQLND----LYHNHQRTVR--EKERELVDC 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  382 QQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKL---VISELRIKLAIKEAEIQKL 458
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFergPFSERQIKNFHTLVIERQE 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  459 HANLTANQLsqslitCNDSQEssklssletepvklgghqvaesvkdqNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAE 538
Cdd:TIGR00606  405 DEAKTAAQL------CADLQS--------------------------KERLKQEQADEIRDEKKGLGRTIELKKEILEKK 452
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  539 NSDLKvNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKivaysSIAAKNAELEQELMEKNEKIRS 618
Cdd:TIGR00606  453 QEELK-FVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVK-----SLQNEKADLDRKLRKLDQEMEQ 526
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  619 LETNINTEHEKICLAFEKAKKihLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLteSK 698
Cdd:TIGR00606  527 LNHHTTTRTQMEMLTKDKMDK--DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL--AS 602
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  699 GEMKKENMKKDEALKALQNQVSEETIkvrqldsaLEICKEElvlhlnQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHS 778
Cdd:TIGR00606  603 LEQNKNHINNELESKEEQLSSYEDKL--------FDVCGSQ------DEESDLERLKEEIEKSSKQRAMLAGATAVYSQF 668
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  779 LQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKcesaAHEADLKRQ 858
Cdd:TIGR00606  669 ITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR----QSIIDLKEK 744
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  859 KVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDmILDQTKTELEKKTNAVKELEKLQHSTETELT 938
Cdd:TIGR00606  745 EIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQGSDLDRT 823
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETelQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERN 1018
Cdd:TIGR00606  824 VQQVNQEKQEK--QHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLI 901
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1019 WELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLRE-KEFIMLQNEQEISQ 1097
Cdd:TIGR00606  902 REIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETELNT 981
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1098 LKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQElrLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKq 1177
Cdd:TIGR00606  982 VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDN--LTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQK- 1058
                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1178 LSKEKDAHGNHLAEELGASKVREahlEARMQAEIKKLSAEVESLKEAYHMEMI 1230
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYE---KEIKHFKKELREPQFRDAEEKYREMMI 1108
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
973-1144 5.77e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 5.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  973 QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQraaqvthldmtIREHRGEMEQKIIKLEGT 1052
Cdd:COG1579      6 LRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED-----------LEKEIKRLELEIEEVEAR 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1053 LEKSELELKEC--NKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEA 1130
Cdd:COG1579     75 IKKYEEQLGNVrnNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAEL 154
                          170
                   ....*....|....
gi 1034558166 1131 IDLGQELRLTREQV 1144
Cdd:COG1579    155 EAELEELEAEREEL 168
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
148-396 6.29e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 6.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  148 LTQSRAKVSMLESAQQQAAS-VPILEEQIINLEAEVSAQDKVLREAENKlEQSQKMVIEKEQSLQESKEECIKLK--VDL 224
Cdd:PRK02224   470 IEEDRERVEELEAELEDLEEeVEEVEERLERAEDLVEAEDRIERLEERR-EDLEELIAERRETIEEKRERAEELRerAAE 548
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  225 LEQTKQGKR--AERQRNEALYNAEELsKAFQQYKKKVAEKLEKVQAEEEILERnLTNCEkenkrlqercglykSELEILK 302
Cdd:PRK02224   549 LEAEAEEKReaAAEAEEEAEEAREEV-AELNSKLAELKERIESLERIRTLLAA-IADAE--------------DEIERLR 612
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  303 EKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILK-----LESELENKDEILRDkfsLMNENRELKVRVAAQNER 377
Cdd:PRK02224   613 EKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARedkerAEEYLEQVEEKLDE---LREERDDLQAEIGAVENE 689
                          250
                   ....*....|....*....
gi 1034558166  378 LDlcqqEIESSRVELRSLE 396
Cdd:PRK02224   690 LE----ELEELRERREALE 704
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
988-1304 6.57e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAELREckmEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTI---REHRGEMeQKIIKLEGTLEKSELELKECN 1064
Cdd:COG3096    285 ERALELRR---ELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYqaaSDHLNLV-QTALRQQEKIERYQEDLEELT 360
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1065 KQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEmesvmkeqEQYIATQYKEAIdlgQELRLTREQV 1144
Cdd:COG3096    361 ERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDV--------QQTRAIQYQQAV---QALEKARALC 429
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1145 QNSHTELAEARHQQVQAQREIERLSSELEDMKQ-LSKEKDAHGNH-----LAEELGASKVRE-AHLEARMQ----AEIKK 1213
Cdd:COG3096    430 GLPDLTPENAEDYLAAFRAKEQQATEEVLELEQkLSVADAARRQFekayeLVCKIAGEVERSqAWQTARELlrryRSQQA 509
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1214 LSAEVESLKEAYH-MEMISHQENHAKWKISADSQKSSVQ------------QLNEQLEKAKLELEEAQDTVSNLHQ---Q 1277
Cdd:COG3096    510 LAQRLQQLRAQLAeLEQRLRQQQNAERLLEEFCQRIGQQldaaeeleellaELEAQLEELEEQAAEAVEQRSELRQqleQ 589
                          330       340
                   ....*....|....*....|....*..
gi 1034558166 1278 VQDRNEVIEAANEALLTKESELTRLQA 1304
Cdd:COG3096    590 LRARIKELAARAPAWLAAQDALERLRE 616
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
1041-1166 6.96e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.43  E-value: 6.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1041 EMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEfimlqnEQEISQLKKEIERTQQRMKEMesvmkEQE 1120
Cdd:PRK00409   531 ELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEA------QQAIKEAKKEADEIIKELRQL-----QKG 599
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1034558166 1121 QYIATQYKEAIDlgqelrlTREQVQNSHTELAEARHQQVQAQREIE 1166
Cdd:PRK00409   600 GYASVKAHELIE-------ARKRLNKANEKKEKKKKKQKEKQEELK 638
mukB PRK04863
chromosome partition protein MukB;
809-1081 7.20e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 7.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  809 ELEDTQTK---LEKQVSKLEQELQKQREssaeKLRKMEEKC---------------ESAAHEADLKRQKVIEltgtARQV 870
Cdd:PRK04863   838 ELRQLNRRrveLERALADHESQEQQQRS----QLEQAKEGLsalnrllprlnlladETLADRVEEIREQLDE----AEEA 909
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  871 KIEMDQYKEELSKMEKEIMHLKRDGENKAmHLSQLDMILDQTKTELEKKTNAVKELEKLQH-----------STETELTE 939
Cdd:PRK04863   910 KRFVQQHGNALAQLEPIVSVLQSDPEQFE-QLKQDYQQAQQTQRDAKQQAFALTEVVQRRAhfsyedaaemlAKNSDLNE 988
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  940 ALQKR-EVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDkkqellEMDQALKERN 1018
Cdd:PRK04863   989 KLRQRlEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADS------GAEERARARR 1062
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034558166 1019 WELKQRaaqvthldmtIREHRGEMEQkiikLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 1081
Cdd:PRK04863  1063 DELHAR----------LSANRSRRNQ----LEKQLTFCEAEMDNLTKKLRKLERDYHEMREQV 1111
PLN02939 PLN02939
transferase, transferring glycosyl groups
482-691 8.29e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 8.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  482 KLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELL 561
Cdd:PLN02939   171 KINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELI 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  562 EKASNSSKLeSEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQE-LMEKNEKIRSLETNINTEHEKICLAfekakki 640
Cdd:PLN02939   251 EVAETEERV-FKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDcWWEKVENLQDLLDRATNQVEKAALV------- 322
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034558166  641 hLEQHKEMEKQIERLEAQLEKKDqQFKEQEKTMSMLQQDIICKQHHLESLD 691
Cdd:PLN02939   323 -LDQNQDLRDKVDKLEASLKEAN-VSKFSSYKVELLQQKLKLLEERLQASD 371
mukB PRK04863
chromosome partition protein MukB;
988-1311 9.67e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 9.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  988 DLTAELRECKMEIEDKK---------QELLE--------------------MDQALKERNwEL-----KQRAAQVTHLDM 1033
Cdd:PRK04863   234 DMEAALRENRMTLEAIRvtqsdrdlfKHLITestnyvaadymrhanerrvhLEEALELRR-ELytsrrQLAAEQYRLVEM 312
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1034 -----TIREHRGEMEQKI-------------IKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEI 1095
Cdd:PRK04863   313 arelaELNEAESDLEQDYqaasdhlnlvqtaLRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEV 392
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1096 SQLKKEIERTQQRMkemesvmkEQEQYIATQYKEAIdlgQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDM 1175
Cdd:PRK04863   393 DELKSQLADYQQAL--------DVQQTRAIQYQQAV---QALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSL 461
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1176 KQ-LSKEKDAHGNH-----LAEELGASKVR-EAHLEA----RMQAEIKKLSAEVESLKEAYH-MEMISHQENHAKwKISA 1243
Cdd:PRK04863   462 EQkLSVAQAAHSQFeqayqLVRKIAGEVSRsEAWDVArellRRLREQRHLAEQLQQLRMRLSeLEQRLRQQQRAE-RLLA 540
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034558166 1244 DSQKSSVQQLNEQlekaklelEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEK 1311
Cdd:PRK04863   541 EFCKRLGKNLDDE--------DELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA 600
mukB PRK04863
chromosome partition protein MukB;
810-1200 1.05e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  810 LEDTQTKLEKQV---SKLEQEL----------------QKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV 870
Cdd:PRK04863   309 LVEMARELAELNeaeSDLEQDYqaasdhlnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAA 388
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  871 KIEMDQYKEELSKMEKEIMHLKRdgenKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETE 950
Cdd:PRK04863   389 EEEVDELKSQLADYQQALDVQQT----RAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQK 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  951 LQNAhgelKSTLRQLQELRDVLQKA--QLSLEEKYTTIKDLTAELRECKMEIEDKKQelLEMDQALKERNWELKQRAAQV 1028
Cdd:PRK04863   465 LSVA----QAAHSQFEQAYQLVRKIagEVSRSEAWDVARELLRRLREQRHLAEQLQQ--LRMRLSELEQRLRQQQRAERL 538
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1029 thldmtirehRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKeieRTQQR 1108
Cdd:PRK04863   539 ----------LAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA---RAPAW 605
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1109 MKEMESVMKEQEQYIATQyKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSseledmkQLSKEKDAHGNH 1188
Cdd:PRK04863   606 LAAQDALARLREQSGEEF-EDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLS-------QPGGSEDPRLNA 677
                          410
                   ....*....|..
gi 1034558166 1189 LAEELGASKVRE 1200
Cdd:PRK04863   678 LAERFGGVLLSE 689
PTZ00121 PTZ00121
MAEBL; Provisional
161-355 1.12e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  161 AQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNE 240
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEE 1658
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  241 ALYNAEELSKAFQQYKKKvAEKLEKVQAEEEILERNLTNCEKENKRLQErcgLYKSELEILK--EKLRQLKEENNNGKEK 318
Cdd:PTZ00121  1659 NKIKAAEEAKKAEEDKKK-AEEAKKAEEDEKKAAEALKKEAEEAKKAEE---LKKKEAEEKKkaEELKKAEEENKIKAEE 1734
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1034558166  319 LRIMA---VKNSEVMAQLTESRQSILKLESELENKDEILR 355
Cdd:PTZ00121  1735 AKKEAeedKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
513-1008 1.20e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 43.66  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  513 QYEKERQRLVTGIEELRTKLIQIEAENSDLKvnmahrtSQFQLIQEELLEKASNSSKLESEMTkkcsqllTLEKQLEEKi 592
Cdd:pfam10174  293 QLKQELSKKESELLALQTKLETLTNQNSDCK-------QHIEVLKESLTAKEQRAAILQTEVD-------ALRLRLEEK- 357
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  593 vayssiaaknaelEQELMEKNEKIRSLEtninteHEKICLAFE----------KAKKIHLEQhkemeKQIERLEAQLEKK 662
Cdd:pfam10174  358 -------------ESFLNKKTKQLQDLT------EEKSTLAGEirdlkdmldvKERKINVLQ-----KKIENLQEQLRDK 413
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  663 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTEskgemkkenmkKDEALKALQNQVSEETIKVRqldsaleickEELvl 742
Cdd:pfam10174  414 DKQLAGLKERVKSLQTDSSNTDTALTTLEEALSE-----------KERIIERLKEQREREDRERL----------EEL-- 470
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  743 hlnqlegnkEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVS 822
Cdd:pfam10174  471 ---------ESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLK 541
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  823 KLEQ--ELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAM 900
Cdd:pfam10174  542 KAHNaeEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVA 621
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  901 HLsqldmildQTKTELEKKTNAvkELEKLQHSTETELTEALQKREVLETelqnaHGELKSTLRQLQELRDVLQKAQLSLE 980
Cdd:pfam10174  622 NI--------KHGQQEMKKKGA--QLLEEARRREDNLADNSQQLQLEEL-----MGALEKTRQELDATKARLSSTQQSLA 686
                          490       500
                   ....*....|....*....|....*...
gi 1034558166  981 EKYTTIKDLTAELRECKMEIEDKKQELL 1008
Cdd:pfam10174  687 EKDGHLTNLRAERRKQLEEILEMKQEAL 714
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
497-680 1.48e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  497 QVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKV--NMAHRTSQFQLIQEELLEKASNSSKLESEM 574
Cdd:COG3206    156 ALAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQknGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  575 TKKCSQLLTLEKQLEEKIVA---------YSSIAAKNAELEQELMEK--------------NEKIRSLETNINTEHEKIC 631
Cdd:COG3206    236 AEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELsarytpnhpdvialRAQIAALRAQLQQEAQRIL 315
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1034558166  632 LAFEKAKKIHLEQHKEMEKQIERLEAQLekkdQQFKEQEKTMSMLQQDI 680
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREV 360
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
189-887 1.65e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  189 LREAENKLEQSQ--KMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEAlyNAEELSKAFQQ---YKKKVAEKL 263
Cdd:pfam01576  358 LEELTEQLEQAKrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEG--QLQELQARLSEserQRAELAEKL 435
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  264 EKVQAEEEILERNLTNCEKENKRLQERCGLYKSEL----EILKE----------KLRQLKEENNNGKEKLRIMAVKNSEV 329
Cdd:pfam01576  436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLqdtqELLQEetrqklnlstRLRQLEDERNSLQEQLEEEEEAKRNV 515
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  330 MAQLTESRQSIL----KLESELENKDEILRDKFSLMNENRELKVRV---AAQNERLD----LCQQEIESSRVELRSLEKI 398
Cdd:pfam01576  516 ERQLSTLQAQLSdmkkKLEEDAGTLEALEEGKKRLQRELEALTQQLeekAAAYDKLEktknRLQQELDDLLVDLDHQRQL 595
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  399 ISQLPLKRElfGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQ 478
Cdd:pfam01576  596 VSNLEKKQK--KFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSK 673
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  479 ESSKLSSLETEPVKLGGHQVAESVKDQnqhtmnkqyekerqrlvtgIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQE 558
Cdd:pfam01576  674 DDVGKNVHELERSKRALEQQVEEMKTQ-------------------LEELEDELQATEDAKLRLEVNMQALKAQFERDLQ 734
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  559 ELLEKASNSSKLESEmtkkcsQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEknekirsLETNINTEHEKICLAFEKAK 638
Cdd:pfam01576  735 ARDEQGEEKRRQLVK------QVRELEAELEDERKQRAQAVAAKKKLELDLKE-------LEAQIDAANKGREEAVKQLK 801
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  639 KIHlEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEmkkenmkKDEALKALQNQ 718
Cdd:pfam01576  802 KLQ-AQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQE-------RDELADEIASG 873
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  719 VSEETI---KVRQLDSALEICKEElvlhLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQ--ETSEQNVILQHTL 793
Cdd:pfam01576  874 ASGKSAlqdEKRRLEARIAQLEEE----LEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQksESARQQLERQNKE 949
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  794 QQQQQMLQQETIRnGELEDTQTKLEKQVSKLEQELQ---KQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQV 870
Cdd:pfam01576  950 LKAKLQEMEGTVK-SKFKSSIAALEAKIAQLEEQLEqesRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKDQAEKG 1028
                          730
                   ....*....|....*..
gi 1034558166  871 KIEMDQYKEELSKMEKE 887
Cdd:pfam01576 1029 NSRMKQLKRQLEEAEEE 1045
46 PHA02562
endonuclease subunit; Provisional
958-1191 1.88e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  958 LKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQ----ELLEMDQALKErnwELKQRAAQVTHLDM 1033
Cdd:PHA02562   172 NKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQnkydELVEEAKTIKA---EIEELTDELLNLVM 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1034 TIR---EHRGEMEQKIIKLEGTLEKSELELK---------ECNKQIESLNDKLQNAKEQLREKEfimlqneQEISQLKKE 1101
Cdd:PHA02562   249 DIEdpsAALNKLNTAAAKIKSKIEQFQKVIKmyekggvcpTCTQQISEGPDRITKIKDKLKELQ-------HSLEKLDTA 321
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1102 IERTQQRMKEmesvmkeqeqyIATQYKEAIDLGQELRLTREQVQNShtelaeaRHQQVQAQREIERLSSEL----EDMKQ 1177
Cdd:PHA02562   322 IDELEEIMDE-----------FNEQSKKLLELKNKISTNKQSLITL-------VDKAKKVKAAIEELQAEFvdnaEELAK 383
                          250
                   ....*....|....
gi 1034558166 1178 LSKEKDAHGNHLAE 1191
Cdd:PHA02562   384 LQDELDKIVKTKSE 397
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
1064-1182 1.94e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1064 NKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDlgQELRLTREQ 1143
Cdd:PRK00409   519 NELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEAD--EIIKELRQL 596
                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1034558166 1144 VQNSHTELAEarHQQVQAQREIERLSSELEDMKQLSKEK 1182
Cdd:PRK00409   597 QKGGYASVKA--HELIEARKRLNKANEKKEKKKKKQKEK 633
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
806-1016 1.97e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  806 RNGELEDTQTKLEKQVSKLEQELQkQRESSAEKLRKmEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKME 885
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKELE-EAEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALR 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  886 KEImhlkRDGENKAMHLSQlDMILDQTKTELEKKTNAVKELEKL---QHSTETELTEALQK-REVLETELQNAHGELKST 961
Cdd:COG3206    247 AQL----GSGPDALPELLQ-SPVIQQLRAQLAELEAELAELSARytpNHPDVIALRAQIAAlRAQLQQEAQRILASLEAE 321
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166  962 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE 1016
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
809-1336 1.97e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.82  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  809 ELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEI 888
Cdd:pfam07111  141 ELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  889 MHLKR---------------DGENKAM-----HLSQLDMILDQTKTELEKKTNAVKELEKLQhstETELTEALQKREVLE 948
Cdd:pfam07111  221 ESLRKyvgeqvppevhsqtwELERQELldtmqHLQEDRADLQATVELLQVRVQSLTHMLALQ---EEELTRKIQPSDSLE 297
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  949 TELQNAHGELKSTLRQLQELRDVLQKAQ-LSLEEKYTTIKDLTAELREckmEIEDKKQELLEMDQALKERNWELKQRAAQ 1027
Cdd:pfam07111  298 PEFPKKCRSLLNRWREKVFALMVQLKAQdLEHRDSVKQLRGQVAELQE---QVTSQSQEQAILQRALQDKAAEVEVERMS 374
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1028 VTHLDMTI---REHRGEMEQKIIKLE--------------GTLEKSELELKECNKQIESLNDKLQNAKEQ------LREK 1084
Cdd:pfam07111  375 AKGLQMELsraQEARRRQQQQTASAEeqlkfvvnamsstqIWLETTMTRVEQAVARIPSLSNRLSYAVRKvhtikgLMAR 454
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1085 EFIMLQNEQEISQLKKEIERTQQRMK-EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQ--- 1160
Cdd:pfam07111  455 KVALAQLRQESCPPPPPAPPVDADLSlELEQLREERNRLDAELQLSAHLIQQEVGRAREQGEAERQQLSEVAQQLEQelq 534
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1161 -AQREIERLSSELEDMKQLSKEKDAHGNHLAEELG--------ASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMIS 1231
Cdd:pfam07111  535 rAQESLASVGQQLEVARQGQQESTEEAASLRQELTqqqeiygqALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVS 614
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1232 HQENHAKwkisADSQKSSVQQLNEQLEKAKLEleEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEK 1311
Cdd:pfam07111  615 LRQIQHR----ATQEKERNQELRRLQDEARKE--EGQRLARRVQELERDKNLMLATLQQEGLLSRYKQQRLLAVLPSGLD 688
                          570       580
                   ....*....|....*....|....*
gi 1034558166 1312 AEDIKFLPAPFTSPTEIMPDVQDPK 1336
Cdd:pfam07111  689 KKSVVSSPRPECSASAPIPAAVPTR 713
PRK12705 PRK12705
hypothetical protein; Provisional
232-380 2.31e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.39  E-value: 2.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  232 KRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNltncekENKRLQERCGLYKSELEILKEKLRQLKEE 311
Cdd:PRK12705    33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRERE------ELQREEERLVQKEEQLDARAEKLDNLENQ 106
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034558166  312 NNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESElENKDEILRDKFSLMNEnrELKVRVAAQNERLDL 380
Cdd:PRK12705   107 LEEREKALSARELELEELEKQLDNELYRVAGLTPE-QARKLLLKLLDAELEE--EKAQRVKKIEEEADL 172
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
768-982 2.38e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  768 LQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 847
Cdd:COG4942     32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  848 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENkamhlsqldmiLDQTKTELEKKTNAVKELE 927
Cdd:COG4942    112 ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-----------LAALRAELEAERAELEALL 180
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166  928 KLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 982
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
867-1017 2.69e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  867 ARqVKIEMDQYKEELSKMEKEIMHLKRDgenkamhlsQLDMILDQTKTELEKKTNAVKELEKLQHSTEtELTEALQKREV 946
Cdd:COG0542    400 AR-VRMEIDSKPEELDELERRLEQLEIE---------KEALKKEQDEASFERLAELRDELAELEEELE-ALKARWEAEKE 468
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  947 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIK-DLTAElreckmEI----------------EDKKQELLE 1009
Cdd:COG0542    469 LIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLReEVTEE------DIaevvsrwtgipvgkllEGEREKLLN 542

                   ....*...
gi 1034558166 1010 MDQALKER 1017
Cdd:COG0542    543 LEEELHER 550
WEMBL pfam05701
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...
875-1291 2.75e-03

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".


Pssm-ID: 461718 [Multi-domain]  Cd Length: 562  Bit Score: 42.32  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  875 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEK-KTNAVK-ELEKLQHSTETELTE----------ALQ 942
Cdd:pfam05701   38 KLVELELEKVQEEIPEYKKQSEAAEAAKAQVLEELESTKRLIEElKLNLERaQTEEAQAKQDSELAKlrveemeqgiADE 117
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  943 KREVLETELQNAHGELKSTLRQLQELR---DVLQKAQLSL-EEKYTTIK---DLTAELRECKMEIEDKKQELLEMDQALK 1015
Cdd:pfam05701  118 ASVAAKAQLEVAKARHAAAVAELKSVKeelESLRKEYASLvSERDIAIKraeEAVSASKEIEKTVEELTIELIATKESLE 197
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1016 ernwelkqrAAQVTHLDMTIREHRGEM--EQKIIKLEGTLEKSELELKECNKQIESLND---KLQNAKEqlrekefiMLQ 1090
Cdd:pfam05701  198 ---------SAHAAHLEAEEHRIGAALarEQDKLNWEKELKQAEEELQRLNQQLLSAKDlksKLETASA--------LLL 260
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1091 NeqeisqLKKEI-ERTQQRMKEmESVMKEQEQYIATQYKEAIDLGQ-ELRLTREQVQNSHTELAEARHQQVQAQREIERL 1168
Cdd:pfam05701  261 D------LKAELaAYMESKLKE-EADGEGNEKKTSTSIQAALASAKkELEEVKANIEKAKDEVNCLRVAAASLRSELEKE 333
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1169 SSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAyhmemisHQEnhakwkisADSQKS 1248
Cdd:pfam05701  334 KAELASLRQREGMASIAVSSLEAELNRTKSEIALVQAKEKEAREKMVELPKQLQQA-------AQE--------AEEAKS 398
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1034558166 1249 SVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEA 1291
Cdd:pfam05701  399 LAQAAREELRKAKEEAEQAKAAASTVESRLEAVLKEIEAAKAS 441
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
902-1289 2.90e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  902 LSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQK-REVLETELQNAH-------------GELKSTLRQLQE 967
Cdd:PRK04778   107 INEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLyRELRKSLLANRFsfgpaldelekqlENLEEEFSQFVE 186
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  968 L---------RDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQraaqvTHLDMTIREH 1038
Cdd:PRK04778   187 LtesgdyveaREILDQLEEELAALEQIMEEIPELLKELQTELPDQLQELKAGYRELVEEGYHLDH-----LDIEKEIQDL 261
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1039 RGEMEQKIIKLEgtleksELELKECNKQIESLNDKLQNAKEQLrEKEFIMlqneqeisqlKKEIERTQQRMKEMESVMKE 1118
Cdd:PRK04778   262 KEQIDENLALLE------ELDLDEAEEKNEEIQERIDQLYDIL-EREVKA----------RKYVEKNSDTLPDFLEHAKE 324
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1119 QEQyiatqykeaiDLGQELRLTREQVQNSHTELAEARhqqvQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASkv 1198
Cdd:PRK04778   325 QNK----------ELKEEIDRVKQSYTLNESELESVR----QLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEI-- 388
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1199 rEAHLEArMQAEIKKLSAEVESLKEAyhmEMISHQE-NHAKWKISADSQK---------------------SSVQQLNEQ 1256
Cdd:PRK04778   389 -LKQLEE-IEKEQEKLSEMLQGLRKD---ELEAREKlERYRNKLHEIKRYleksnlpglpedylemffevsDEIEALAEE 463
                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1034558166 1257 LEKAKL-------ELEEAQDTVSNLHQQVqdrNEVIEAAN 1289
Cdd:PRK04778   464 LEEKPInmeavnrLLEEATEDVETLEEET---EELVENAT 500
COG5022 COG5022
Myosin heavy chain [General function prediction only];
997-1305 3.02e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 3.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  997 KMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQK---IIKLEGTLEK----SELELKECNKQIES 1069
Cdd:COG5022    767 ALKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYlacIIKLQKTIKRekklRETEEVEFSLKAEV 846
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1070 LNDKLQNAKEqlREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY---KEAIDLGQEL--------- 1137
Cdd:COG5022    847 LIQKFGRSLK--AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLeleSEIIELKKSLssdlienle 924
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1138 ----RLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQA---- 1209
Cdd:COG5022    925 fkteLIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKElael 1004
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1210 --EIKKLSAEVESLKEAYHmeMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQvQDRNEVIEA 1287
Cdd:COG5022   1005 skQYGALQESTKQLKELPV--EVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLR-RENSLLDDK 1081
                          330
                   ....*....|....*...
gi 1034558166 1288 ANEALLTKESELTRLQAK 1305
Cdd:COG5022   1082 QLYQLESTENLLKTINVK 1099
PRK12704 PRK12704
phosphodiesterase; Provisional
574-723 3.19e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  574 MTKKCSQLLTLEKQLEEKIVAYSSIAAKNA--ELEQELMEKNEKIRSletnintehekiclAFEKAKKIHLEQHKEMEKQ 651
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIkkEALLEAKEEIHKLRN--------------EFEKELRERRNELQKLEKR 90
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034558166  652 IERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKE-----NMKKDEALKALQNQVSEET 723
Cdd:PRK12704    91 LLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQElerisGLTAEEAKEILLEKVEEEA 167
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
85-280 3.64e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 3.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166   85 CKISGSSTDFQKKPRDKMFSSS----------APVDQEIKSLREKLNKLRQQNACL------VTQNHSLMTKFESIHFEL 148
Cdd:COG4913    581 GQVKGNGTRHEKDDRRRIRSRYvlgfdnraklAALEAELAELEEELAEAEERLEALeaeldaLQERREALQRLAEYSWDE 660
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  149 TQSRAKVSMLESAQQQ----AASVPILEEqiinLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDL 224
Cdd:COG4913    661 IDVASAEREIAELEAElerlDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRL 736
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166  225 LEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNC 280
Cdd:COG4913    737 EAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
582-1088 3.69e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 3.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  582 LTLEKQLEEKIVAYSSIAAKNAELEQ--ELMEKNEKIRS---LETNINTEHEKICLAFEKAKKIHLEQHKEmEKQIERLE 656
Cdd:TIGR01612 1226 LFLEKIDEEKKKSEHMIKAMEAYIEDldEIKEKSPEIENemgIEMDIKAEMETFNISHDDDKDHHIISKKH-DENISDIR 1304
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  657 AQLEKKDQQFKEQEKTMSM---LQQDIICKQHHLESLDRLLTESKGEMkkeNMKKDEALKALQNQVSEETIKVRQLDSAL 733
Cdd:TIGR01612 1305 EKSLKIIEDFSEESDINDIkkeLQKNLLDAQKHNSDINLYLNEIANIY---NILKLNKIKKIIDEVKEYTKEIEENNKNI 1381
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  734 --EICKEELVLHL----NQLEGNKEKFEKQLKKKSEEvYCLQKELKIKNHSLQEtsEQNVILQHTLQQQQQMLQQETIRN 807
Cdd:TIGR01612 1382 kdELDKSEKLIKKikddINLEECKSKIESTLDDKDID-ECIKKIKELKNHILSE--ESNIDTYFKNADENNENVLLLFKN 1458
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  808 GELEDTQTKLEKQVSKleQELQKQRESSAEKLRKMEEKCESAAHEADlKRQKVIEltgtarQVKIEMDQYKEELS----- 882
Cdd:TIGR01612 1459 IEMADNKSQHILKIKK--DNATNDHDFNINELKEHIDKSKGCKDEAD-KNAKAIE------KNKELFEQYKKDVTellnk 1529
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  883 ----KMEKEIMHLKRDGENKAMHLSQLDmilDQTKTELEKKTNAVKELEKLQHSTETE--------------------LT 938
Cdd:TIGR01612 1530 ysalAIKNKFAKTKKDSEIIIKEIKDAH---KKFILEAEKSEQKIKEIKKEKFRIEDDaakndksnkaaidiqlslenFE 1606
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLE-EKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER 1017
Cdd:TIGR01612 1607 NKFLKISDIKKKINDCLKETESIEKKISSFSIDSQDTELKENgDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKI 1686
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1018 NWELKQRAAQ-----VTHLDMTIREHRGEMEQKIIKLEGTLEK-------SELELKECNKQIESLNDKLQNAKEQLREKE 1085
Cdd:TIGR01612 1687 EIDVDQHKKNyeigiIEKIKEIAIANKEEIESIKELIEPTIENlissfntNDLEGIDPNEKLEEYNTEIGDIYEEFIELY 1766

                   ...
gi 1034558166 1086 FIM 1088
Cdd:TIGR01612 1767 NII 1769
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
880-1029 4.02e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 4.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  880 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHG--E 957
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkE 90
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034558166  958 LKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVT 1029
Cdd:COG1579     91 YEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
939-1222 4.04e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  939 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERN 1018
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1019 WELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESL----------NDKLQNAKEQLREK---- 1084
Cdd:pfam01576   85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLeedillledqNSKLSKERKLLEERisef 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1085 EFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQRE 1164
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE 244
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1165 IERLSSELED-------MKQLSKEKDAHGNHLAEELGASKVREAHLEARMqaeiKKLSAEVESLK 1222
Cdd:pfam01576  245 LQAALARLEEetaqknnALKKIRELEAQISELQEDLESERAARNKAEKQR----RDLGEELEALK 305
ATG17_like pfam04108
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ...
901-1224 4.91e-03

Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.


Pssm-ID: 427715 [Multi-domain]  Cd Length: 360  Bit Score: 40.83  E-value: 4.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  901 HLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLE 980
Cdd:pfam04108   22 LLEELVVLLAKIAFLRRGLSVQLANLEKVREGLEKVLNELKKDFKQLLKDLDAALERLEETLDKLRNTPVEPALPPGEEK 101
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  981 EKY-------TTIKDLTAELRECKMEIEDKKQElleMDQALKERNWELKQraaqvTHLDMTIREHRGEMEQKIIKLEGTL 1053
Cdd:pfam04108  102 QKTlldfideDSVEILRDALKELIDELQAAQES---LDSDLKRFDDDLRD-----LQKELESLSSPSESISLIPTLLKEL 173
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1054 EKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQ----NEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKE 1129
Cdd:pfam04108  174 ESLEEEMASLLESLTNHYDQCVTAVKLTEGGRAEMLEvlenDARELDDVVPELQDRLDEMENNYERLQKLLEQKNSLIDE 253
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1130 AIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKE-KDAHGNHLAEelgasKVREAHLEARMQ 1208
Cdd:pfam04108  254 LLSALQLIAEIQSRLPEYLAALKEFEERWEEEKETIEDYLSELEDLREFYEGfPSAYGSLLLE-----VERRREWAEKMK 328
                          330
                   ....*....|....*.
gi 1034558166 1209 AEIKKLSAEVESLKEA 1224
Cdd:pfam04108  329 KILRKLAEELDRLQEE 344
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
834-1045 5.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 5.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  834 SSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTK 913
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  914 TELEKKTNAVKELEKL--QHSTETELTEALQKREVLET------------ELQNAHGELKSTLRQLQELRDVLQKAQLSL 979
Cdd:COG4942     97 AELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAvrrlqylkylapARREQAEELRADLAELAALRAELEAERAEL 176
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034558166  980 EEKYTTIKDLTAELREckmEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQK 1045
Cdd:COG4942    177 EALLAELEEERAALEA---LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
291-392 5.78e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 41.20  E-value: 5.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  291 CGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDE---ILRDKFSLMNE-NRE 366
Cdd:pfam05911  676 NDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKSQLQESEQLIAELRSELASLKEsnsLAETQLKCMAEsYED 755
                           90       100
                   ....*....|....*....|....*.
gi 1034558166  367 LKVRVAAQNERLDLCQQEIESSRVEL 392
Cdd:pfam05911  756 LETRLTELEAELNELRQKFEALEVEL 781
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
969-1292 5.89e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.18  E-value: 5.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  969 RDVLQKAQLSLEEKYTTIKDltAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRgEMEQKIIK 1048
Cdd:PRK02224   179 ERVLSDQRGSLDQLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHE-ERREELET 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1049 LEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEfimlqneQEISQLKKEIERTQqrmKEMESVMKEQEqyiatqyk 1128
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELE-------EERDDLLAEAGLDD---ADAEAVEARRE-------- 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1129 eaidlgqELRLTREQVQNshtELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASkvrEAHLEARmQ 1208
Cdd:PRK02224   318 -------ELEDRDEELRD---RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEA---REAVEDR-R 383
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1209 AEIKKLSAEVESLKEAyhmemishqenhakwkisadsqkssVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAA 1288
Cdd:PRK02224   384 EEIEELEEEIEELRER-------------------------FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                   ....
gi 1034558166 1289 NEAL 1292
Cdd:PRK02224   439 RERV 442
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
967-1300 6.20e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 6.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  967 ELRDVLQKAQLSLEEkytTIKDLTAELRECKMEIE-------------------------------DKKQELLEmdQALK 1015
Cdd:COG3096    215 SLRDYLLPENSGVRK---AFQDMEAALRENRMTLEairvtqsdrdlfkhliteatnyvaadymrhaNERRELSE--RALE 289
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1016 ERNWELKQR----AAQVTHLDMTiREHrGEMEQKIIKLEGTLEKSELELK------ECNKQIESLNDKLQNAKEQLREKE 1085
Cdd:COG3096    290 LRRELFGARrqlaEEQYRLVEMA-REL-EELSARESDLEQDYQAASDHLNlvqtalRQQEKIERYQEDLEELTERLEEQE 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1086 FIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYI------ATQYKEAIdlgQELRLTREQVQNSHTELAEARHQQV 1159
Cdd:COG3096    368 EVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqtrAIQYQQAV---QALEKARALCGLPDLTPENAEDYLA 444
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1160 QAQREIERLSSELEDMKQ-LSKEKDAHGNH-----LAEELGASKVRE-AHLEARMQ----AEIKKLSAEVESLKEAYH-M 1227
Cdd:COG3096    445 AFRAKEQQATEEVLELEQkLSVADAARRQFekayeLVCKIAGEVERSqAWQTARELlrryRSQQALAQRLQQLRAQLAeL 524
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1228 EMISHQENHAKwKISADSQKSSVQQLN--EQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELT 1300
Cdd:COG3096    525 EQRLRQQQNAE-RLLEEFCQRIGQQLDaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELA 598
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
111-310 6.52e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 6.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  111 QEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLR 190
Cdd:PRK03918   231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELR 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  191 EAENKLE--QSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEK-LEKVQ 267
Cdd:PRK03918   311 EIEKRLSrlEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLtPEKLE 390
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1034558166  268 AEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKE 310
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
914-1130 7.86e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 7.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  914 TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAEL 993
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  994 RECKMEIE------------------DKKQELLEMDQALKErnwELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEK 1055
Cdd:COG3883     96 YRSGGSVSyldvllgsesfsdfldrlSALSKIADADADLLE---ELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034558166 1056 SELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEA 1130
Cdd:COG3883    173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
943-1121 8.47e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 40.78  E-value: 8.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  943 KREVLETELQNAHGELKSTLRQLQELRdvlQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELK 1022
Cdd:pfam05667  304 EKLQFTNEAPAATSSPPTKVETEEELQ---QQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNE 380
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1023 QRAAQVTHLDMTIrEHRGEMEQKIIKLEGTLEKSELELKECNKQIES----LNDKLQNAKEQLREKEFimlqneqEISQL 1098
Cdd:pfam05667  381 ELEKQYKVKKKTL-DLLPDAEENIAKLQALVDASAQRLVELAGQWEKhrvpLIEEYRALKEAKSNKED-------ESQRK 452
                          170       180
                   ....*....|....*....|...
gi 1034558166 1099 KKEIERTQQRMKEMESVMKEQEQ 1121
Cdd:pfam05667  453 LEEIKELREKIKEVAEEAKQKEE 475
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
848-1173 8.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 8.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  848 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKR------DGENKAMHLSQLDMiLDQTKTELEKKTN 921
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswDEIDVASAEREIAE-LEAELERLDASSD 685
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166  922 AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTikDLTAELREckmEIE 1001
Cdd:COG4913    686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA--LLEERFAA---ALG 760
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1002 DKKQEllEMDQALKERNWELKQRAAQ-VTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNkQIEslNDKLQNAKEQ 1080
Cdd:COG4913    761 DAVER--ELRENLEERIDALRARLNRaEEELERAMRAFNREWPAETADLDADLESLPEYLALLD-RLE--EDGLPEYEER 835
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034558166 1081 LREkefimLQNEQEI-------SQLKKEIERTQQRMKEMESVMKE----QEQYI-----ATQYKEAIDLGQELRLTREQV 1144
Cdd:COG4913    836 FKE-----LLNENSIefvadllSKLRRAIREIKERIDPLNDSLKRipfgPGRYLrlearPRPDPEVREFRQELRAVTSGA 910
                          330       340
                   ....*....|....*....|....*....
gi 1034558166 1145 QNSHTELAEARHQQVqaQREIERLSSELE 1173
Cdd:COG4913    911 SLFDEELSEARFAAL--KRLIERLRSEEE 937
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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