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Conserved domains on  [gi|1034638318|ref|XP_016863195|]
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alpha-adducin isoform X4 [Homo sapiens]

Protein Classification

class II aldolase/adducin head domain-containing protein( domain architecture ID 842)

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations

Gene Symbol:  ADD3
PubMed:  10581174

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Aldolase_II super family cl00214
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 145-391 1.58e-98

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


The actual alignment was detected with superfamily member PRK07044:

Pssm-ID: 469663  Cd Length: 252  Bit Score: 304.46  E-value: 1.58e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 225 SAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKVLIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLNPEKYKAKSRSPGSPVGEGtgsppkwqIGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAG--------AGELAWPALLRK 242

                         250
                  ....*....|
gi 1034638318 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 585-708 1.00e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  585 GSEENLDEAREQKEKSPPDQPAVP-HPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP--DEPSEALGFPMLEKE 661
Cdd:PHA03307   100 PAREGSPTPPGPSSPDPPPPTPPPaSPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVasDAASSRQAALPLSSP 179

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1034638318  662 EEAHRPPSP--TEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSD 708
Cdd:PHA03307   180 EETARAPSSppAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSA 228
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 145-391 1.58e-98

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 304.46  E-value: 1.58e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 225 SAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKVLIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLNPEKYKAKSRSPGSPVGEGtgsppkwqIGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAG--------AGELAWPALLRK 242

                         250
                  ....*....|
gi 1034638318 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 142-352 4.65e-68

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 222.63  E-value: 4.65e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 142 EKLLRcKLAAFYRLADLFGWSQLIYNHITTRvNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIV--DRGSTNLGvnqa 219
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVegKKPSSETP---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 220 gftLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL---GEVAYHDYHGILvDEEEKVLIQKNLG-PKSK 295
Cdd:cd00398    75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfPNSK 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034638318 296 VLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGG--PDNLVLLNPEKYKAK 352
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQlpPISLELLNKEYLRKH 209
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 145-341 1.99e-57

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 194.28  E-value: 1.99e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVnsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGstnlGVNQAGFTLH 224
Cdd:COG0235     6 LREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 225 SAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPIS-PEAL-SLGEVAYHDYHGIlVDEEEKVLIQKNLGpKSKVLILRNH 302
Cdd:COG0235    80 LAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEqTEAAaFLGDVPVVPYAGP-GTEELAEAIAEALG-DRPAVLLRNH 157

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1034638318 303 GLVSVGESVEEAFYYIHNLVVACEIQVRTLAsAGGPDNL 341
Cdd:COG0235   158 GVVVWGKDLAEAFDRAEVLEEAARIQLLALA-LGGPLVL 195
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 147-329 1.39e-55

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 188.14  E-value: 1.39e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 147 CKLAAFYRLADLFGWSQLIYNHITTRVnsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGstnLGVNqAGFTLHSA 226
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG---LKPS-SETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 227 IYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGiLVDEEEKVLIQKNLGPKSKVLILRNHGL 304
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYT-PGTEELGERIAEALGGDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1034638318 305 VSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 149-329 4.52e-53

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 181.68  E-value: 4.52e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  149 LAAFYRLADLFGWSQLIYNHITTRVNsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTnlGVNQAGFTLHSAIY 228
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  229 AARPDVKCVVHIHTPAGAAVSAM--KCGLLPIS-PEALSLGEVAYHDYHGILVDEEEKV-LIQKNLGPK---SKVLILRN 301
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEqAAAFLGGEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1034638318  302 HGLVSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 585-708 1.00e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  585 GSEENLDEAREQKEKSPPDQPAVP-HPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP--DEPSEALGFPMLEKE 661
Cdd:PHA03307   100 PAREGSPTPPGPSSPDPPPPTPPPaSPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVasDAASSRQAALPLSSP 179

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1034638318  662 EEAHRPPSP--TEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSD 708
Cdd:PHA03307   180 EETARAPSSppAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSA 228
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 603-702 5.09e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.83  E-value: 5.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEA-SPEP 681
Cdd:NF040712  212 ARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAeTPEA 291

                          90       100
                  ....*....|....*....|.
gi 1034638318 682 APDPAPVAEEAAPSAVEEGAA 702
Cdd:NF040712  292 AEPPAPAPAAPAAPAAPEAEE 312
ZipA COG3115
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ...
 575-699 3.38e-03

Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442349 [Multi-domain]  Cd Length: 298  Bit Score: 40.06  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 575 YRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEED------LVPEPTTGDDSD--AATFKPTLPDLSP 646
Cdd:COG3115    29 ERRSSFRDKPSKRDVLLDDDGIGEVRVVAAEAPERVEPEASFDAEDEvrepdqEEVDPLLDDEADieAAPAEPVRWAGTA 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034638318 647 DEPSEALGFPMLEKEEEAHRPPSPTEAPTEAsPEPAPDPAPVAEEAAPSAVEE 699
Cdd:COG3115   109 AAVEPAPEQEAYEEAGPAGESAEQEDAPAEE-PEAEAPAEEALAAELCAEPEE 160
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 145-391 1.58e-98

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 304.46  E-value: 1.58e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 225 SAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKVLIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLNPEKYKAKSRSPGSPVGEGtgsppkwqIGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAG--------AGELAWPALLRK 242

                         250
                  ....*....|
gi 1034638318 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 142-352 4.65e-68

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 222.63  E-value: 4.65e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 142 EKLLRcKLAAFYRLADLFGWSQLIYNHITTRvNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIV--DRGSTNLGvnqa 219
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVegKKPSSETP---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 220 gftLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL---GEVAYHDYHGILvDEEEKVLIQKNLG-PKSK 295
Cdd:cd00398    75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfPNSK 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034638318 296 VLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGG--PDNLVLLNPEKYKAK 352
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQlpPISLELLNKEYLRKH 209
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 145-341 1.99e-57

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 194.28  E-value: 1.99e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVnsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGstnlGVNQAGFTLH 224
Cdd:COG0235     6 LREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 225 SAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPIS-PEAL-SLGEVAYHDYHGIlVDEEEKVLIQKNLGpKSKVLILRNH 302
Cdd:COG0235    80 LAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEqTEAAaFLGDVPVVPYAGP-GTEELAEAIAEALG-DRPAVLLRNH 157

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1034638318 303 GLVSVGESVEEAFYYIHNLVVACEIQVRTLAsAGGPDNL 341
Cdd:COG0235   158 GVVVWGKDLAEAFDRAEVLEEAARIQLLALA-LGGPLVL 195
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 147-329 1.39e-55

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 188.14  E-value: 1.39e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 147 CKLAAFYRLADLFGWSQLIYNHITTRVnsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGstnLGVNqAGFTLHSA 226
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG---LKPS-SETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 227 IYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGiLVDEEEKVLIQKNLGPKSKVLILRNHGL 304
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYT-PGTEELGERIAEALGGDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1034638318 305 VSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 149-329 4.52e-53

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 181.68  E-value: 4.52e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  149 LAAFYRLADLFGWSQLIYNHITTRVNsEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTnlGVNQAGFTLHSAIY 228
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  229 AARPDVKCVVHIHTPAGAAVSAM--KCGLLPIS-PEALSLGEVAYHDYHGILVDEEEKV-LIQKNLGPK---SKVLILRN 301
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEqAAAFLGGEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1034638318  302 HGLVSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
PRK06661 PRK06661
hypothetical protein; Provisional
 149-334 1.64e-43

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 156.92  E-value: 1.64e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 149 LAAFYRLADLFGWSQLIYNHITTRvNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrgSTNLGVNQAGFTLHSAIY 228
Cdd:PRK06661    7 LAAAYRIMAYLSLDDHTYTHLSAR-PKNADFYYIYPFGLRFEEVTTENLLKVSLDGQILE--GEEYQYNKTGYFIHGSIY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 229 AARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGE-VAYHDYHGILVDEE-EKVLIQKNLGpKSKVLILRNHGLVS 306
Cdd:PRK06661   84 KTRPDISAIFHYHTPASIAVSALKCGLLPISQWALHFYDrISYHNYNSLALDADkQSSRLVNDLK-QNYVMLLRNHGAIT 162

                         170       180
                  ....*....|....*....|....*...
gi 1034638318 307 VGESVEEAFYYIHNLVVACEIQVRTLAS 334
Cdd:PRK06661  163 CGKTIHEAMFYTYHLEQACKTQCLLNST 190
PRK06208 PRK06208
class II aldolase/adducin family protein;
148-361 2.81e-41

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 152.07  E-value: 2.81e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 148 KLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrgsTNLGVNQAGFTLHSAI 227
Cdd:PRK06208   46 RLAAAFRLFARFGFDEGLAGHITARDPELPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVE---GDRPLNRAAFAIHSAI 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 228 YAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGE--VAYHDYHGILVDEEEKVLIQKNLGPKsKVLILRNHGLV 305
Cdd:PRK06208  123 HEARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAFYEdhALFDDFTGVVVDTSEGRRIAAALGTH-KAVILQNHGLL 201

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034638318 306 SVGESVEEA-FYYIhNLVVACEIQVrtLASAGGPdnLVLLNPEKYKAKSRSPGSPVG 361
Cdd:PRK06208  202 TVGPSVDAAaWWFI-ALERACQTQL--LAEAAGP--PQPIDHETARHTRSQVGSEYG 253
PRK06486 PRK06486
aldolase;
114-385 1.79e-26

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 109.42  E-value: 1.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 114 MA-ALNMSLGMVTPVNDLRGSDSIAYdkgeklLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEV 192
Cdd:PRK06486    1 MAhSLTTDSAPPAGNRPLLDSDAVAQ------ARVDLAACFRAAARHGLEEGICNHFSAVLPGHDDLFLVNPYGYAFSEI 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 193 TASSLVKINLQGDIVD-RGStnlgVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMK-CGLLPISPEALSL-GEVA 269
Cdd:PRK06486   75 TASDLLICDFDGNVLAgRGE----PEATAFFIHARIHRAIPRAKAAFHTHMPYATALSLTEgRPLTTLGQTALKFyGRTA 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 270 Y-HDYHGILVDEEEKVLIQKNLGPKSkVLILRNHGLVSVGESVEEAF---YYihnLVVACEIQVRTLaSAGGPdnLVLLN 345
Cdd:PRK06486  151 VdEDYNGLALDAAEGDRIARAMGDAD-IVFLKNHGVMVCGPRIAEAWddlYY---LERACEVQVLAM-STGRP--LVPVD 223

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1034638318 346 PEKYKAKSRspgspvgegtgsppKWQIGEQE-----FEALMRMLD 385
Cdd:PRK06486  224 PAIAAAVAR--------------QMREGDREsarlhLEALRRTLD 254
PRK07490 PRK07490
hypothetical protein; Provisional
 135-385 2.89e-20

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 90.55  E-value: 2.89e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 135 SIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINlqGDIVDRGSTNL 214
Cdd:PRK07490    1 MTMALSDEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLD--ADDPSTAERPD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 215 GVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCG-LLPISPE-ALSLGEVAYHDYHGILVDEEEKVLIQKNLGP 292
Cdd:PRK07490   79 VPDATAWAIHGQIHRRLPHARCVMHVHSVYATALACLADPtLPPIDQNtARFFNRVAVDTLYGGMALEEEGERLAGLLGD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 293 KSkVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASaGGPdnLVLLNPEkykaksrspgspVGEGTGSppKWQ- 371
Cdd:PRK07490  159 KR-RLLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITALST-GQP--LRVLSDA------------VAEKTAR--DWEd 220

                         250
                  ....*....|....*..
gi 1034638318 372 ---IGEQEFEALMRMLD 385
Cdd:PRK07490  221 ypgFSRQHFAELKALLD 237
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 145-338 5.68e-19

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 87.38  E-value: 5.68e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 145 LRCKLAAFYRLADLFGWSQLIYNHITTRvnSEQEH-FLIVPFGLLYSEVTASSLVKINLQGDIVD-RGSTNlGVNQagft 222
Cdd:PRK07090   31 LRQKLALTCRILFDAGHDSGLAGQITAR--AEAPGtYYTQRLGLGFDEITASNLLLVDEDLNVLDgEGMPN-PANR---- 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 223 LHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAY-HDYHGILVDEEEKVLIQKNLGPKSKVLiLR 300
Cdd:PRK07090  104 FHSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLyDDCAFlKDWPGVPVGNEEGEIISAALGDKRAIL-LS 182

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1034638318 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVrtLASAGGP 338
Cdd:PRK07090  183 HHGQLVAGKSIEEACVLALLIERAARLQL--LAMAAGP 218
PRK08333 PRK08333
aldolase;
143-316 2.97e-13

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 68.70  E-value: 2.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 143 KLLRCKLAAFYRLADLFGWSQLIYNHITTRVNseqEHFLIVPFGLLYSEVTASSLVKINLQGDIVD--RGSTNlgvnqag 220
Cdd:PRK08333    2 RNVKAQLVKYSKLAHERGLTAAFGGNLSIRVG---NLVFIKATGSVMDELTREQVAVIDLNGNQLSsvRPSSE------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 221 FTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLP-ISPEA-LSLGEVAYHDYHGI----LVDEEEKVLIQKNlgpks 294
Cdd:PRK08333   72 YRLHLAVYRNRPDVRAIAHLHPPYSIVASTLLEEELPiITPEAeLYLKKIPILPFRPAgsveLAEQVAEAMKEYD----- 146

                         170       180
                  ....*....|....*....|..
gi 1034638318 295 kVLILRNHGLVSVGESVEEAFY 316
Cdd:PRK08333  147 -AVIMERHGIVTVGRSLREAFY 167
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 176-314 4.30e-12

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 66.18  E-value: 4.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 176 EQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrGSTNLGVNQAGftlHSAIYAARPDVKCVVHIHTPAGAAVSA----M 251
Cdd:PRK06557   41 GTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-GDLKPSSDTAS---HLYVYRHMPDVGGVVHTHSTYATAWAArgepI 116

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034638318 252 KCGLLPISPEAlsLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEA 314
Cdd:PRK06557  117 PCVLTAMADEF--GGPIPVGPFALIGDEAIGKGIVETLKGGRSPAVLMQNHGVFTIGKDAEDA 177
PRK08130 PRK08130
putative aldolase; Validated
 179-316 2.00e-07

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 52.18  E-value: 2.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 179 HFLIVPFGLLYSEVTASSLVKINLQGDIV--DRGSTNLgvnqagfTLHSAIYAARPDVKCVVHIHTPAGAAVSAM----- 251
Cdd:PRK08130   38 GWLVTPTGSCLGRLDPARLSKVDADGNWLsgDKPSKEV-------PLHRAIYRNNPECGAVVHLHSTHLTALSCLggldp 110

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034638318 252 KCGLLPISPEAL-SLGEVAYHDYH--GilvDEEEKVLIQKnLGPKSKVLILRNHGLVSVGESVEEAFY 316
Cdd:PRK08130  111 TNVLPPFTPYYVmRVGHVPLIPYYrpG---DPAIAEALAG-LAARYRAVLLANHGPVVWGSSLEAAVN 174
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
174-338 4.62e-07

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 51.29  E-value: 4.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 174 NSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrGSTnlgVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKC 253
Cdd:PRK06833   34 NREQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVE-GER---KPSSELDMHLIFYRNREDINAIVHTHSPYATTLACLGW 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 254 GLLPISPE-ALSLGEVAYHDYHGI----LVDEEEKVLIQKnlgpksKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQ 328
Cdd:PRK06833  110 ELPAVHYLiAVAGPNVRCAEYATFgtkeLAENAFEAMEDR------RAVLLANHGLLAGANNLKNAFNIAEEIEFCAEIY 183

                         170
                  ....*....|
gi 1034638318 329 VRTlASAGGP 338
Cdd:PRK06833  184 YQT-KSIGEP 192
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
177-333 3.56e-06

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 48.58  E-value: 3.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 177 QEHFLIVPFGLLYSEVTASSLVKINlqgdivDRGSTNLG-VNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGL 255
Cdd:PRK08087   35 QDGMLITPTGIPYEKLTESHIVFVD------GNGKHEEGkLPSSEWRFHMAAYQTRPDANAVVHNHAVHCTAVSILNRPI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 256 --------------LPISPEAlSLG--EVAYHDYHGIlvdeeekvliqknlgPKSKVLILRNHGLVSVGESVEEAFYYIH 319
Cdd:PRK08087  109 paihymiaaaggnsIPCAPYA-TFGtrELSEHVALAL---------------KNRKATLLQHHGLIACEVNLEKALWLAH 172

                         170
                  ....*....|....
gi 1034638318 320 NLVVACEIQVRTLA 333
Cdd:PRK08087  173 EVEVLAQLYLKTLA 186
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 173-327 9.04e-05

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 44.41  E-value: 9.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 173 VNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVD---RGSTNLGVnqagftlHSAIYAARPDVKCVVHIHTP------ 243
Cdd:PRK12348   31 IDRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEgeyRPSSDTAT-------HLELYRRYPSLGGIVHTHSThatawa 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 244 -AGAAVSAMKC-------GLLPISpEALSLGEVAyHDYHgilvDEEEKVLIQkNLGPKSKV----LILRNHGLVSVGESV 311
Cdd:PRK12348  104 qAGLAIPALGTthadyffGDIPCT-RGLSEEEVQ-GEYE----LNTGKVIIE-TLGNAEPLhtpgIVVYQHGPFAWGKDA 176

                         170
                  ....*....|....*.
gi 1034638318 312 EEAfyyIHNLVVACEI 327
Cdd:PRK12348  177 HDA---VHNAVVMEEV 189
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 585-708 1.00e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  585 GSEENLDEAREQKEKSPPDQPAVP-HPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP--DEPSEALGFPMLEKE 661
Cdd:PHA03307   100 PAREGSPTPPGPSSPDPPPPTPPPaSPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVasDAASSRQAALPLSSP 179

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1034638318  662 EEAHRPPSP--TEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGSD 708
Cdd:PHA03307   180 EETARAPSSppAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSA 228
araD PRK13145
L-ribulose-5-phosphate 4-epimerase; Provisional
 173-323 1.03e-04

L-ribulose-5-phosphate 4-epimerase; Provisional


Pssm-ID: 183870 [Multi-domain]  Cd Length: 234  Bit Score: 44.44  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 173 VNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDrGSTNlgvNQAGFTLHSAIYAARPDVKCVVHIHTPAGA----AV 248
Cdd:PRK13145   33 VCRELGRIVIKPSGVDYDELTPENMVVTDLDGNVVE-GDLN---PSSDLPTHVELYKAWPEVGGIVHTHSTEAVgwaqAG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 249 SAMKC----------GLLPISpEALSLGEV--AYHDYHGILVDEEEKvliQKNLGPKS-KVLILRNHGLVSVGESVEEAF 315
Cdd:PRK13145  109 RDIPFygtthadyfyGPIPCA-RSLTKDEVngAYEKETGSVIIEEFE---KRGLDPMAvPGIVVRNHGPFTWGKNPEQAV 184


                  ....*...
gi 1034638318 316 YyiHNLVV 323
Cdd:PRK13145  185 Y--HSVVL 190
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 596-705 2.13e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.08  E-value: 2.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  596 QKEKSPP----DQPAVPH------PPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAH 665
Cdd:PRK10263   376 APEGYPQqsqyAQPAVQYneplqqPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQST 455

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1034638318  666 RPPSPTEAPTEASPEPAPDPAPvaeEAAPSAVEEGAAADP 705
Cdd:PRK10263   456 FAPQSTYQTEQTYQQPAAQEPL---YQQPQPVEQQPVVEP 492
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
591-703 2.20e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.84  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 591 DEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAAtfkPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSP 670
Cdd:PRK07003  437 DRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPA---SDAPPDAAFEPAPRAAAPSAATPAAVPDARAP 513

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1034638318 671 TEAPTEASPEPAPDPAPVAEEAAPSAVEE-----GAAA 703
Cdd:PRK07003  514 AAASREDAPAAAAPPAPEARPPTPAAAAPaaragGAAA 551
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 603-702 5.09e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.83  E-value: 5.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 603 DQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEA-SPEP 681
Cdd:NF040712  212 ARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAeTPEA 291

                          90       100
                  ....*....|....*....|.
gi 1034638318 682 APDPAPVAEEAAPSAVEEGAA 702
Cdd:NF040712  292 AEPPAPAPAAPAAPAAPEAEE 312
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 560-707 8.45e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 8.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  560 GPNPFTTLTdRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEpttgdDSDAATfkp 639
Cdd:PHA03307   259 RPAPITLPT-RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE-----SSSSST--- 329

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034638318  640 tlpdLSPDEPSEALGFPmlekeeeahRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGS 707
Cdd:PHA03307   330 ----SSSSESSRGAAVS---------PGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGR 384
PHA03419 PHA03419
E4 protein; Provisional
 601-691 1.03e-03

E4 protein; Provisional


Pssm-ID: 223079 [Multi-domain]  Cd Length: 200  Bit Score: 41.09  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 601 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTL--------PDLSPDEPSEAlgfpmlEKEEEAHRPPSPTE 672
Cdd:PHA03419   63 PPPCPPSPGHPPQTNDTHEKDLALQPPPGGKKKEKKKKETEkpaqggekPDQGPEAKGEG------EGHEPEDPPPEDTP 136

                          90       100
                  ....*....|....*....|....*
gi 1034638318 673 AP------TEASPEPAPDPAPVAEE 691
Cdd:PHA03419  137 PPpggegeVEGGPSPGPGPGPLDQE 161
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 600-706 1.54e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 600 SPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLS-PDEPSEALGFPMLEKEEEAHRPPSPTEAPTEAS 678
Cdd:PRK07764  695 GAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPlPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAP 774

                          90       100
                  ....*....|....*....|....*...
gi 1034638318 679 PEPAPDPAPVAEEAAPSAVEEGAAADPG 706
Cdd:PRK07764  775 PPSPPSEEEEMAEDDAPSMDDEDRRDAE 802
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 596-707 1.95e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.45  E-value: 1.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 596 QKEKSPPdQPAVPHPPPSTPIKLEEDL------VPEPTTGDDSDA----ATFKPTLPDL--SPDEPSEALGFPMLEKEEE 663
Cdd:PLN03209  355 PIEEEPP-QPKAVVPRPLSPYTAYEDLkpptspIPTPPSSSPASSksvdAVAKPAEPDVvpSPGSASNVPEVEPAQVEAK 433

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034638318 664 AHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPGS 707
Cdd:PLN03209  434 KTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDT 477
PHA03169 PHA03169
hypothetical protein; Provisional
 557-708 2.48e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.11  E-value: 2.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 557 STTGPNPFTTLTD--RELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIkLEEDLVPEPTTG--DDS 632
Cdd:PHA03169   52 TTSGPQVRAVAEQghRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEE-LASGLSPENTSGssPES 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 633 DAATFKPTLP-----DLSPDEPSEALGFP----MLEKEEEAHRPPSPTEAPTEASPEPAPDP--APVAEEAAPSAV---E 698
Cdd:PHA03169  131 PASHSPPPSPpshpgPHEPAPPESHNPSPnqqpSSFLQPSHEDSPEEPEPPTSEPEPDSPGPpqSETPTSSPPPQSppdE 210

                         170
                  ....*....|
gi 1034638318 699 EGAAADPGSD 708
Cdd:PHA03169  211 PGEPQSPTPQ 220
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
602-708 2.71e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.99  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 602 PDQPAVPHPPPSTPikleedlvPEPTTGDDSDAATFKPTLPDLSPDEPSEAlgfpmleKEEEAHRPPSPTEAPTEASPEP 681
Cdd:PRK07003  417 AAAATRAEAPPAAP--------APPATADRGDDAADGDAPVPAKANARASA-------DSRCDERDAQPPADSGSASAPA 481

                          90       100
                  ....*....|....*....|....*..
gi 1034638318 682 APDPAPVAEEAAPSAVEEGAAADPGSD 708
Cdd:PRK07003  482 SDAPPDAAFEPAPRAAAPSAATPAAVP 508
PHA03247 PHA03247
large tegument protein UL36; Provisional
 593-705 2.89e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  593 AREQKEKSPPDQP---------------AVPHPPPSTPIKLEEDLVPE-PTTGDDSDAATFKPTLPdLSPDEPSEALGFP 656
Cdd:PHA03247  2671 GRAAQASSPPQRPrrraarptvgsltslADPPPPPPTPEPAPHALVSAtPLPPGPAAARQASPALP-AAPAPPAVPAGPA 2749

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034638318  657 MLEKEEEAHRPPSPTEAPTEASPE-PAPDPAPVAEEAAPSAVEEGAAADP 705
Cdd:PHA03247  2750 TPGGPARPARPPTTAGPPAPAPPAaPAAGPPRRLTRPAVASLSESRESLP 2799
PHA03247 PHA03247
large tegument protein UL36; Provisional
 591-706 3.04e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 3.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  591 DEAREQKEKSPPDQPAVPHPPPSTpiKLEEDLVPEPTtgdDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAhRPPSP 670
Cdd:PHA03247  2861 DVRRRPPSRSPAAKPAAPARPPVR--RLARPAVSRST---ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQP-QPPPP 2934

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1034638318  671 TEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPG 706
Cdd:PHA03247  2935 PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPG 2970
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 601-707 3.07e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  601 PPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPE 680
Cdd:PHA03307    81 ANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPA 160

                           90       100
                   ....*....|....*....|....*...
gi 1034638318  681 PAPDPAPVAEEAA-PSAVEEGAAADPGS 707
Cdd:PHA03307   161 AVASDAASSRQAAlPLSSPEETARAPSS 188
ZipA COG3115
Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome ...
 575-699 3.38e-03

Cell division protein ZipA, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442349 [Multi-domain]  Cd Length: 298  Bit Score: 40.06  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 575 YRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEED------LVPEPTTGDDSD--AATFKPTLPDLSP 646
Cdd:COG3115    29 ERRSSFRDKPSKRDVLLDDDGIGEVRVVAAEAPERVEPEASFDAEDEvrepdqEEVDPLLDDEADieAAPAEPVRWAGTA 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034638318 647 DEPSEALGFPMLEKEEEAHRPPSPTEAPTEAsPEPAPDPAPVAEEAAPSAVEE 699
Cdd:COG3115   109 AAVEPAPEQEAYEEAGPAGESAEQEDAPAEE-PEAEAPAEEALAAELCAEPEE 160
rne PRK10811
ribonuclease E; Reviewed
 587-702 4.77e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.41  E-value: 4.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318  587 EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHR 666
Cdd:PRK10811   889 EAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEV 968

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1034638318  667 PPSPTEAPTE-ASPEPAPDPAPVAEEAAPSAVEEGAA 702
Cdd:PRK10811   969 VVAEPEVVAQpAAPVVAEVAAEVETVTAVEPEVAPAQ 1005
PHA03379 PHA03379
EBNA-3A; Provisional
 592-699 5.00e-03

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 40.43  E-value: 5.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 592 EAREQKEKSPPDQPA-VPHPPP---STPIKLEEDLVPEPTTGDDSDAATFKPTLP-DLSPDEPSEALGFPMLEKEEEAH- 665
Cdd:PHA03379  426 EVPQSLETATSHGSAqVPEPPPvhdLEPGPLHDQHSMAPCPVAQLPPGPLQDLEPgDQLPGVVQDGRPACAPVPAPAGPi 505

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1034638318 666 -RP--PSPTEAPTEASPEPAPDPAPVAEEAAPSAVEE 699
Cdd:PHA03379  506 vRPweASLSQVPGVAFAPVMPQPMPVEPVPVPTVALE 542
PHA03169 PHA03169
hypothetical protein; Provisional
 573-725 6.72e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 39.57  E-value: 6.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 573 EEYRREVERKQKGSEENL-DEAREQKEK-SPPDQPAVPHPPPSTPIKLE--EDLVPEPTTGDDSDAAT--FKPTLPDlSP 646
Cdd:PHA03169   97 SESVGSPTPSPSGSAEELaSGLSPENTSgSSPESPASHSPPPSPPSHPGphEPAPPESHNPSPNQQPSsfLQPSHED-SP 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 647 DEPSEALGFPMlEKEEEAHRPPSPTEAPTEASP--EPAPDPAPVAEEAapsavEEGAAADPGSDGSPGKSPSKKKKKFRT 724
Cdd:PHA03169  176 EEPEPPTSEPE-PDSPGPPQSETPTSSPPPQSPpdEPGEPQSPTPQQA-----PSPNTQQAVEHEDEPTEPEREGPPFPG 249


                  .
gi 1034638318 725 P 725
Cdd:PHA03169  250 H 250
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 624-702 8.99e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 39.33  E-value: 8.99e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034638318 624 PEPTTGDDSDAATFKPTlPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEpAPDPAPVAEEAAPSAVEEGAA 702
Cdd:PHA03269   25 NIPIPELHTSAATQKPD-PAPAPHQAASRAPDPAVAPTSAASRKPDLAQAPTPAASE-KFDPAPAPHQAASRAPDPAVA 101
PRK08660 PRK08660
aldolase;
224-327 9.54e-03

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 38.01  E-value: 9.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034638318 224 HSAIYAaRPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALS-LGE--VAYHDYHGILVDEEEKVLIQKNlgpksKVLILR 300
Cdd:PRK08660   72 HRAIYR-RTSAKAIVHAHPPYAVALSLLEDEIVPLDSEGLYfLGTipVVGGDIGSGELAENVARALSEH-----KGVVVR 145

                          90       100
                  ....*....|....*....|....*..
gi 1034638318 301 NHGLVSVGESVEEAFYYIHNLVVACEI 327
Cdd:PRK08660  146 GHGTFAIGKTLEEAYIYTSQLEHSCKV 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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