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Conserved domains on  [gi|1034671442|ref|XP_016870660|]
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G kinase-anchoring protein 1 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 39-225 2.84e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.50  E-value: 2.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442   39 KKDKRKNHQGKDRPLTVSLKDFHS-EDHISKKTEELSSSQTL--SHDGGFFNRLEDDVHKILIREKRREQLTEYNGTdnc 115
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEElREELEELQEELKEAEEEleELTAELQELEEKLEELRLEVSELEEEIEELQKE--- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442  116 tAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKyKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIK 195
Cdd:TIGR02168  290 -LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190
                   ....*....|....*....|....*....|
gi 1034671442  196 NELTIQVTSLHAALEQERSKVKVLQAELAK 225
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIAS 397
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 39-225 2.84e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.50  E-value: 2.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442   39 KKDKRKNHQGKDRPLTVSLKDFHS-EDHISKKTEELSSSQTL--SHDGGFFNRLEDDVHKILIREKRREQLTEYNGTdnc 115
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEElREELEELQEELKEAEEEleELTAELQELEEKLEELRLEVSELEEEIEELQKE--- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442  116 tAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKyKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIK 195
Cdd:TIGR02168  290 -LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190
                   ....*....|....*....|....*....|
gi 1034671442  196 NELTIQVTSLHAALEQERSKVKVLQAELAK 225
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIAS 397
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 39-225 2.84e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.50  E-value: 2.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442   39 KKDKRKNHQGKDRPLTVSLKDFHS-EDHISKKTEELSSSQTL--SHDGGFFNRLEDDVHKILIREKRREQLTEYNGTdnc 115
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEElREELEELQEELKEAEEEleELTAELQELEEKLEELRLEVSELEEEIEELQKE--- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034671442  116 tAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKyKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIK 195
Cdd:TIGR02168  290 -LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190
                   ....*....|....*....|....*....|
gi 1034671442  196 NELTIQVTSLHAALEQERSKVKVLQAELAK 225
Cdd:TIGR02168  368 EELESRLEELEEQLETLRSKVAQLELQIAS 397
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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