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Conserved domains on  [gi|1034675123|ref|XP_016885272|]
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lysine-specific demethylase 6A isoform X9 [Homo sapiens]

Protein Classification

KDM6 family histone demethylase( domain architecture ID 11421451)

KDM6 family histone demethylase, similar to lysine-specific demethylase 6A (KDM6A), also called UTX (ubiquitously-transcribed TPR protein on the X chromosome) that specifically demethylates 'Lys-27' of histone H3, and UTY (ubiquitously-transcribed TPR protein on the Y chromosome) that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3

CATH:  1.25.40.10|2.60.120.10
EC:  1.14.11.-
Gene Ontology:  GO:0005515|GO:0032452|GO:0031490|GO:0046872
PubMed:  26059336|21153002|10517866|30708253|22404999|11165500|14697267|19478949
SCOP:  4001344|3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 1106-1214 1.08e-36

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


:

Pssm-ID: 396791  Cd Length: 114  Bit Score: 134.35  E-value: 1.08e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123 1106 QLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNN-------LNFLMGSWWPnlEDLYEANV 1178
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1034675123 1179 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV 1214
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 130-378 6.25e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 109.05  E-value: 6.25e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  130 AAFLYG---LGLVYFHYNAFQWAIKAFQEVLYVDPSfcrAKEIHLRLGLMFKVNTDYESSLKHFQlALVDCNPctlSNAE 206
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQ-KLLERDP---DRAE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  207 IQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLSAQVK-ATVLQQLG-WmhhtvdllgDKatkesyAIQYLQKSLEADPN 282
Cdd:COG2956     78 ALLELAQDYLKAGLLDRAEELLEKLLELDpdDAEALRLlAEIYEQEGdW---------EK------AIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  283 SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLY 362
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*.
gi 1034675123  363 ESCNQPQDAIKCYLNA 378
Cdd:COG2956    223 EKLGDPEEALELLRKA 238
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 1072-1136 3.90e-08

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


:

Pssm-ID: 214721  Cd Length: 58  Bit Score: 51.10  E-value: 3.90e-08
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  1072 QLHELTKLPafvrvvSAGNLLSHVGHTILGMNT-VQLYMKVPGSRTPGHQENNNfcSVNINIGPGD 1136
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVgPYLYMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 75-161 1.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG5010     72 ESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAALQ 146


                   ....*..
gi 1034675123  155 EVLYVDP 161
Cdd:COG5010    147 RALGTSP 153
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 1106-1214 1.08e-36

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 134.35  E-value: 1.08e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123 1106 QLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNN-------LNFLMGSWWPnlEDLYEANV 1178
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1034675123 1179 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV 1214
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 130-378 6.25e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 109.05  E-value: 6.25e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  130 AAFLYG---LGLVYFHYNAFQWAIKAFQEVLYVDPSfcrAKEIHLRLGLMFKVNTDYESSLKHFQlALVDCNPctlSNAE 206
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQ-KLLERDP---DRAE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  207 IQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLSAQVK-ATVLQQLG-WmhhtvdllgDKatkesyAIQYLQKSLEADPN 282
Cdd:COG2956     78 ALLELAQDYLKAGLLDRAEELLEKLLELDpdDAEALRLlAEIYEQEGdW---------EK------AIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  283 SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLY 362
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*.
gi 1034675123  363 ESCNQPQDAIKCYLNA 378
Cdd:COG2956    223 EKLGDPEEALELLRKA 238
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 1072-1136 3.90e-08

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 51.10  E-value: 3.90e-08
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  1072 QLHELTKLPafvrvvSAGNLLSHVGHTILGMNT-VQLYMKVPGSRTPGHQENNNfcSVNINIGPGD 1136
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVgPYLYMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 87-375 1.13e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.16  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   87 AEGKVESD--FFCQLGHFNLLLEDYPKALSAYQRYYSLQSdywKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFC 164
Cdd:TIGR02917  355 ALGLDPDDpaALSLLGEAYLALGDFEKAAEYLAKATELDP---ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELG 431

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  165 RAKEI----HLRLGLMFKVNTDYESSLKHfqlalvdcnpcTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLS 238
Cdd:TIGR02917  432 RADLLlilsYLRSGQFDKALAAAKKLEKK-----------QPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEpdFFP 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  239 AqvkATVLQQLgwmhhtvDLLGDKATKesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASA 318
Cdd:TIGR02917  501 A---AANLARI-------DIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEI 567

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675123  319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 375
Cdd:TIGR02917  568 EPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 75-161 1.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG5010     72 ESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAALQ 146


                   ....*..
gi 1034675123  155 EVLYVDP 161
Cdd:COG5010    147 RALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
130-163 1.79e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.10  E-value: 1.79e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034675123  130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSF 163
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 130-163 4.24e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 4.24e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1034675123   130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSF 163
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 170-234 4.88e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 40.80  E-value: 4.88e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675123  170 HLRLGLMFK-VNTDYESSLKHFQLALVDCNPCTLS--NAE---IQFHIAHLYEtqrKYHSAKEAYEQLLQT 234
Cdd:cd24145     10 ILRKALYYEsDKPDPQKALKYYKEALEQADELGMDpfSDEvtgIRIKIAEMLE---KLGMYKAAYEVLERL 77
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 1106-1214 1.08e-36

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 134.35  E-value: 1.08e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123 1106 QLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNN-------LNFLMGSWWPnlEDLYEANV 1178
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1034675123 1179 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV 1214
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 130-378 6.25e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 109.05  E-value: 6.25e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  130 AAFLYG---LGLVYFHYNAFQWAIKAFQEVLYVDPSfcrAKEIHLRLGLMFKVNTDYESSLKHFQlALVDCNPctlSNAE 206
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQ-KLLERDP---DRAE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  207 IQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLSAQVK-ATVLQQLG-WmhhtvdllgDKatkesyAIQYLQKSLEADPN 282
Cdd:COG2956     78 ALLELAQDYLKAGLLDRAEELLEKLLELDpdDAEALRLlAEIYEQEGdW---------EK------AIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  283 SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLY 362
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*.
gi 1034675123  363 ESCNQPQDAIKCYLNA 378
Cdd:COG2956    223 EKLGDPEEALELLRKA 238
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 98-378 6.31e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 109.05  E-value: 6.31e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   98 QLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPsfcRAKEIHLRLGLMF 177
Cdd:COG2956     13 FKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLERDP---DRAEALLELAQDY 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  178 KVNTDYESSLKHFQlALVDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQV---KATVLQQlgwmhh 254
Cdd:COG2956     87 LKAGLLDRAEELLE-KLLELDP---DDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAyceLAELYLE------ 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  255 tvdlLGDKATkesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQP 334
Cdd:COG2956    157 ----QGDYDE----AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDP 228

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1034675123  335 MDALQAYICAVQLDHGhAAAWMDLGTLYESCNQPQDAIKCYLNA 378
Cdd:COG2956    229 EEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 171-415 6.88e-26

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 109.05  E-value: 6.88e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  171 LRLGLMFKVNTDYESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkatvLQQLG 250
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEAL-ELDP---ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEA----LLELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  251 WMHHTVDLLgDKAtkesyaIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 330
Cdd:COG2956     84 QDYLKAGLL-DRA------EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  331 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATR------------SKSCSNTSALAARIKYLQ 398
Cdd:COG2956    157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEqdpdylpalprlAELYEKLGDPEEALELLR 236

                          250
                   ....*....|....*..
gi 1034675123  399 ACKPHHPNTEPVLGLSQ 415
Cdd:COG2956    237 KALELDPSDDLLLALAD 253
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
204-375 5.15e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.78  E-value: 5.15e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  204 NAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkatvLQQLGWMHHtvdLLGDKATkesyAIQYLQKSLEADPNS 283
Cdd:COG0457      7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA----LYNLGLAYL---RLGRYEE----ALADYEQALELDPDD 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  284 GQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 363
Cdd:COG0457     76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                          170
                   ....*....|..
gi 1034675123  364 SCNQPQDAIKCY 375
Cdd:COG0457    156 KLGRYEEALELL 167
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
243-378 3.05e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 94.69  E-value: 3.05e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  243 ATVLQQLGWMHHtvdLLGDKATkesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWC 322
Cdd:COG0457      8 AEAYNNLGLAYR---RLGRYEE----AIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  323 SIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
Cdd:COG0457     81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERA 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 269-375 8.62e-20

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 86.60  E-value: 8.62e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG4235      2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                           90       100
                   ....*....|....*....|....*..
gi 1034675123  349 HGHAAAWMDLGTLYESCNQPQDAIKCY 375
Cdd:COG4235     82 PDNPEALYLLGLAAFQQGDYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
128-319 1.05e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 90.07  E-value: 1.05e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  128 KNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMFKVNTDYESSLKHFQLALvDCNPctlSNAEI 207
Cdd:COG0457      6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQAL-ELDP---DDAEA 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  208 QFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkatvLQQLGWMHHtvdLLGDKATkesyAIQYLQKSLEADPNSGQSW 287
Cdd:COG0457     79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEA----LYNLGLALL---ELGRYDE----AIEAYERALELDPDDADAL 147

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1034675123  288 YFLGRCYSSIGKVQDAFISYRQSIDKSEASAD 319
Cdd:COG0457    148 YNLGIALEKLGRYEEALELLEKLEAAALAALL 179
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
277-380 2.26e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 86.21  E-value: 2.26e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  277 LEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWM 356
Cdd:COG0457      1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                           90       100
                   ....*....|....*....|....
gi 1034675123  357 DLGTLYESCNQPQDAIKCYLNATR 380
Cdd:COG0457     81 NLGLALQALGRYEEALEDYDKALE 104
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 202-430 3.09e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 90.44  E-value: 3.09e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  202 LSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGwmhhtvdLLGDKATkesyAIQYLQKSLEADP 281
Cdd:COG3914     41 LGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQ-------ALGRYEE----ALALYRRALALNP 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  282 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTL 361
Cdd:COG3914    110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNA 189

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675123  362 YESCNQPQDAIKCY-----LNATRSKSCSNtsALAARIKyLQACKPHHPNTEPVLGLSQTPISQQSLPLHMIPS 430
Cdd:COG3914    190 LQDLGRLEEAIAAYrraleLDPDNADAHSN--LLFALRQ-ACDWEVYDRFEELLAALARGPSELSPFALLYLPD 260
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 269-378 9.47e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.53  E-value: 9.47e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG4783     23 AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD 102

                           90       100       110
                   ....*....|....*....|....*....|
gi 1034675123  349 HGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
Cdd:COG4783    103 PEHPEAYLRLARAYRALGRPDEAIAALEKA 132
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
75-280 1.37e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 1.37e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGKVESdfFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG0457     26 EAIEDYEKALELDPDDAEA--LYNLGLAYLRLGRYEEALADYEQALELDPD---DAEALNNLGLALQALGRYEEALEDYD 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  155 EVLYVDPSFCRAK----EIHLRLGlmfkvntDYESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQ 230
Cdd:COG0457    101 KALELDPDDAEALynlgLALLELG-------RYDEAIEAYERAL-ELDP---DDADALYNLGIALEKLGRYEEALELLEK 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034675123  231 LLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEAD 280
Cdd:COG0457    170 LEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 205-348 1.81e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 1.81e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  205 AEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkatvLQQLGWMHHTvdlLGDKATkesyAIQYLQKSLEADPNSG 284
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA----FALLGEILLQ---LGDLDE----AIVLLHEALELDPDEP 72

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675123  285 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG4783     73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 75-280 9.03e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 9.03e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGKVESdfFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG2956     94 RAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE---NAHAYCELAELYLEQGDYDEAIEALE 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  155 EVLYVDPSFCRAK----EIHLRLGlmfkvntDYESSLKHFQLALVDcNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQ 230
Cdd:COG2956    169 KALKLDPDCARALlllaELYLEQG-------DYEEAIAALERALEQ-DP---DYLPALPRLAELYEKLGDPEEALELLRK 237

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1034675123  231 LLQTENLSAQV--KATVLQQLGwmhhtvdllGDKAtkesyAIQYLQKSLEAD 280
Cdd:COG2956    238 ALELDPSDDLLlaLADLLERKE---------GLEA-----ALALLERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 210-380 1.42e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.33  E-value: 1.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  210 HIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESY--AIQYLQKSLEADPNSGQSW 287
Cdd:COG3914      2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLalAAGEAAAAAAALLLLAALL 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  288 YFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQ 367
Cdd:COG3914     82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGR 161

                          170
                   ....*....|...
gi 1034675123  368 PQDAIKCYLNATR 380
Cdd:COG3914    162 LEEAIAALRRALE 174
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 200-365 3.21e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.18  E-value: 3.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  200 CTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkatvLQQLGWMHHTVDLLGDkatkesyAIQYLQKSLEA 279
Cdd:COG3914     73 ALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA----LFNLGNLLLALGRLEE-------ALAALRRALAL 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  280 DPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMD-L 358
Cdd:COG3914    142 NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNlL 221


                   ....*..
gi 1034675123  359 GTLYESC 365
Cdd:COG3914    222 FALRQAC 228
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 98-233 6.79e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.44  E-value: 6.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   98 QLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFcraKEIHLRLGLMF 177
Cdd:COG4783      9 ALAQALLLAGDYDEAEALLEKALELDPD---NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLGLAL 82

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  178 KVNTDYESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQ 233
Cdd:COG4783     83 LKAGDYDEALALLEKAL-KLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 98-341 1.87e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 1.87e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   98 QLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMF 177
Cdd:COG3914     46 LLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA---LFNLGNLL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  178 KVNTDYESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQtenLSAQvKATVLQQLGWMHHtvd 257
Cdd:COG3914    123 LALGRLEEALAALRRAL-ALNP---DFAEAYLNLGEALRRLGRLEEAIAALRRALE---LDPD-NAEALNNLGNALQ--- 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  258 llgdKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDaFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDA 337
Cdd:COG3914    192 ----DLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV-YDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266


                   ....
gi 1034675123  338 LQAY 341
Cdd:COG3914    267 LALA 270
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
269-348 1.52e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 1.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAfISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG3063     11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 98-194 5.80e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 5.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   98 QLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMF 177
Cdd:COG4235     22 LLGRAYLRLGRYDEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA---LYLLGLAA 95

                           90
                   ....*....|....*..
gi 1034675123  178 KVNTDYESSLKHFQLAL 194
Cdd:COG4235     96 FQQGDYAEAIAAWQKLL 112
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
278-373 2.78e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.77  E-value: 2.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  278 EADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMD 357
Cdd:COG4785     67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                           90
                   ....*....|....*.
gi 1034675123  358 LGTLYESCNQPQDAIK 373
Cdd:COG4785    147 RGIALYYLGRYELAIA 162
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 269-348 5.34e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 5.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG5010     73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 204-319 6.96e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 6.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  204 NAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDllgdkatkesyAIQYLQKSLEADPNS 283
Cdd:COG4235     16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEE-----------AEELLERALALDPDN 84

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1034675123  284 GQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASAD 319
Cdd:COG4235     85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 285-380 9.83e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.20  E-value: 9.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  285 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 364
Cdd:COG4783      5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                           90
                   ....*....|....*.
gi 1034675123  365 CNQPQDAIKCYLNATR 380
Cdd:COG4783     85 AGDYDEALALLEKALK 100
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 67-194 2.87e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 2.87e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   67 ARTKALLG---KAVRCYESLIlkAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHY 143
Cdd:COG4783     11 AQALLLAGdydEAEALLEKAL--ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD---EPEARLNLGLALLKA 85

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034675123  144 NAFQWAIKAFQEVLYVDPSFcraKEIHLRLGLMFKVNTDYESSLKHFQLAL 194
Cdd:COG4783     86 GDYDEALALLEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKAL 133
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 269-378 3.06e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.58  E-value: 3.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 348
Cdd:COG5010     39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                           90       100       110
                   ....*....|....*....|....*....|
gi 1034675123  349 HGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
Cdd:COG5010    119 PDNPNAYSNLAALLLSLGQDDEAKAALQRA 148
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 1072-1136 3.90e-08

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 51.10  E-value: 3.90e-08
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  1072 QLHELTKLPafvrvvSAGNLLSHVGHTILGMNT-VQLYMKVPGSRTPGHQENNNfcSVNINIGPGD 1136
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVgPYLYMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 286-399 4.70e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 4.70e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  286 SWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 365
Cdd:COG2956     10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                           90       100       110
                   ....*....|....*....|....*....|....
gi 1034675123  366 NQPQDAIKCYLNATRSKScSNTSALAARIKYLQA 399
Cdd:COG2956     90 GLLDRAEELLEKLLELDP-DDAEALRLLAEIYEQ 122
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
293-375 6.60e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 6.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  293 CYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQaYICAVQLDHGHAAAWMDLGTLYESCNQPQDAI 372
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                   ...
gi 1034675123  373 KCY 375
Cdd:COG3063     80 AYL 82
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 130-283 9.93e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.50  E-value: 9.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMFKVNTDYESSLKHFQLALVDcNPctlSNAEIQF 209
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALEL-DP---DEPEARL 76

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675123  210 HIAHLYETQRKYHSAKEAYEQLLQTENLSAQV---KATVLQQLGwmhhtvdllgdkatKESYAIQYLQKSLEADPNS 283
Cdd:COG4783     77 NLGLALLKAGDYDEALALLEKALKLDPEHPEAylrLARAYRALG--------------RPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 87-375 1.13e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.16  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   87 AEGKVESD--FFCQLGHFNLLLEDYPKALSAYQRYYSLQSdywKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFC 164
Cdd:TIGR02917  355 ALGLDPDDpaALSLLGEAYLALGDFEKAAEYLAKATELDP---ENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELG 431

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  165 RAKEI----HLRLGLMFKVNTDYESSLKHfqlalvdcnpcTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLS 238
Cdd:TIGR02917  432 RADLLlilsYLRSGQFDKALAAAKKLEKK-----------QPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEpdFFP 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  239 AqvkATVLQQLgwmhhtvDLLGDKATKesyAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASA 318
Cdd:TIGR02917  501 A---AANLARI-------DIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEI 567

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034675123  319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 375
Cdd:TIGR02917  568 EPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 104-238 1.46e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 1.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  104 LLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFcraKEIHLRLGLMFKVNTDY 183
Cdd:COG5010     28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDK 104

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034675123  184 ESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLS 238
Cdd:COG5010    105 DEAKEYYEKAL-ALSP---DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 108-423 1.84e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  108 DYPKALSAYQRYYSLQSDYWkNAAFLygLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKE----IHLRLGLMfkvnTDY 183
Cdd:TIGR02917  276 NYEDARETLQDALKSAPEYL-PALLL--AGASEYQLGNLEQAYQYLNQILKYAPNSHQARRllasIQLRLGRV----DEA 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  184 ESSLKHFqLALVDCNPCTLSNAEIqfhiAHLyeTQRKYHSAKEAYEQLLQTENLSAQVKAtvlqQLGWMHHtvdLLGDKa 263
Cdd:TIGR02917  349 IATLSPA-LGLDPDDPAALSLLGE----AYL--ALGDFEKAAEYLAKATELDPENAAART----QLGISKL---SQGDP- 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  264 tkeSYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYIC 343
Cdd:TIGR02917  414 ---SEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEK 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  344 AVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNT-----SALAAR--------IKYLQACKPHHPNTEPV 410
Cdd:TIGR02917  491 ALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRailalAGLYLRtgneeeavAWLEKAAELNPQEIEPA 570

                          330
                   ....*....|...
gi 1034675123  411 LGLSQTPISQQSL 423
Cdd:TIGR02917  571 LALAQYYLGKGQL 583
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 85-320 1.89e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 1.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   85 LKAEGKVESDFF-CQLGHFNLLLEDyPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPS- 162
Cdd:TIGR02917  658 LKRALELKPDNTeAQIGLAQLLLAA-KRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSs 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  163 --FCRAKEIHLRLGLMFKVNTDYESSLKHfqlalvdcNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQtenlSAQ 240
Cdd:TIGR02917  737 qnAIKLHRALLASGNTAEAVKTLEAWLKT--------HP---NDAVLRTALAELYLAQKDYDKAIKHYQTVVK----KAP 801

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  241 VKATVLQQLGWmhhtvdLLGDKatKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADT 320
Cdd:TIGR02917  802 DNAVVLNNLAW------LYLEL--KDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAI 873
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 108-194 2.97e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.29  E-value: 2.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  108 DYPKALSAYQRYYSL--QSDYWKNAafLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNTDYES 185
Cdd:COG1729      8 DYDEAIAAFKAFLKRypNSPLAPDA--LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDK 85


                   ....*....
gi 1034675123  186 SLKHFQLAL 194
Cdd:COG1729     86 ARATLEELI 94
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
139-233 4.21e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 4.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  139 VYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMFKVNTDYESSLKhFQLALvDCNPctlSNAEIQFHIAHLYETQ 218
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADA---LNNLGLLLLEQGRYDEAIA-LEKAL-KLDP---NNAEALLNLAELLLEL 72

                           90
                   ....*....|....*
gi 1034675123  219 RKYHSAKEAYEQLLQ 233
Cdd:COG3063     73 GDYDEALAYLERALE 87
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 269-341 4.34e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.91  E-value: 4.34e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034675123  269 AIQYLQKSLEADPNS---GQSWYFLGRCYSSIGKVQDAFISYRQSID---KSEASADTWCSIGVLYQQQNQPMDALQAY 341
Cdd:COG1729     12 AIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATL 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 165-375 4.88e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 4.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  165 RAKEIHLRLGLMFKVNTDYESSLKHFQlALVDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--NLSAQVk 242
Cdd:TIGR02917  599 DSPEAWLMLGRAQLAAGDLNKAVSSFK-KLLALQP---DSALALLLLADAYAVMKNYAKAITSLKRALELKpdNTEAQI- 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  243 atVLQQLgwmhhtvdLLGDKATKESYAI-QYLQKsleADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIdKSEASADTW 321
Cdd:TIGR02917  674 --GLAQL--------LLAAKRTESAKKIaKSLQK---QHPKAALGFELEGDLYLRQKDYPAAIQAYRKAL-KRAPSSQNA 739

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034675123  322 CSIGVLYQQQNQPMDALQAYIcAVQLDH-GHAAAWMDLGTLYESCNQPQDAIKCY 375
Cdd:TIGR02917  740 IKLHRALLASGNTAEAVKTLE-AWLKTHpNDAVLRTALAELYLAQKDYDKAIKHY 793
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 128-234 5.60e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 5.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  128 KNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFcraKEIHLRLGLMFKVNTDYESSLKHFQLALvDCNPctlSNAEI 207
Cdd:COG4235     15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERAL-ALDP---DNPEA 87

                           90       100
                   ....*....|....*....|....*..
gi 1034675123  208 QFHIAHLYETQRKYHSAKEAYEQLLQT 234
Cdd:COG4235     88 LYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 75-161 1.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG5010     72 ESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAALQ 146


                   ....*..
gi 1034675123  155 EVLYVDP 161
Cdd:COG5010    147 RALGTSP 153
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
96-166 1.82e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.60  E-value: 1.82e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675123   96 FCQLGHFNLLLEDYPKALSAYQRYYSLQSDYwknAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRA 166
Cdd:COG4785    110 YNNRGLAYLLLGDYDAALEDFDRALELDPDY---AYAYLNRGIALYYLGRYELAIADLEKALELDPNDPER 177
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 111-281 2.54e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.11  E-value: 2.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  111 KALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGlmfkvntDYESSLKHF 190
Cdd:COG5010      5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-------DFEESLALL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  191 QLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVK---ATVLQQLGwmhhtvdllgdkatKES 267
Cdd:COG5010     78 EQAL-QLDP---NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYsnlAALLLSLG--------------QDD 139

                          170
                   ....*....|....
gi 1034675123  268 YAIQYLQKSLEADP 281
Cdd:COG5010    140 EAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 326-380 3.62e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 3.62e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034675123  326 VLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATR 380
Cdd:COG5010     62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116
TPR_1 pfam00515
Tetratricopeptide repeat;
130-163 1.79e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.10  E-value: 1.79e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034675123  130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSF 163
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 136-320 2.22e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 44.25  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  136 LGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMFKVNTDYESSLKHFQLALvdcnpcTLSNAEIQFHI---A 212
Cdd:TIGR02521   37 LALGYLEQGDLEVAKENLDKALEHDPDDYLA---YLALALYYQQLGELEKAEDSFRRAL------TLNPNNGDVLNnygT 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  213 HLYEtQRKYHSAKEAYEQLLQTENLSAQvkATVLQQLGwmhhtvdLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGR 292
Cdd:TIGR02521  108 FLCQ-QGKYEQAMQQFEQAIEDPLYPQP--ARSLENAG-------LCALKAGDFDKAEKYLTRALQIDPQRPESLLELAE 177

                          170       180
                   ....*....|....*....|....*...
gi 1034675123  293 CYSSIGKVQDAFISYRQSIDKSEASADT 320
Cdd:TIGR02521  178 LYYLRGQYKDARAYLERYQQTYNQTAES 205
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 204-350 3.32e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 44.52  E-value: 3.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  204 NAEIQFHIAHLYETQRKYHSAkeayEQLLQtENLSAQVKATVLQQLGwmhhtvDLLGDKATKesyAIQYLQKSLEADPNS 283
Cdd:COG3071    192 DPELAAAYARALIALGDHDEA----ERLLR-EALKRQWDPRLVRLYG------RLQGGDPAK---QLKRAEKWLKKHPND 257

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  284 GQSWYFLGR-CYSS--IGKVQDAFisyRQSIdKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHG 350
Cdd:COG3071    258 PDLLLALGRlCLRNqlWGKAREYL---EAAL-ALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
75-165 3.33e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 3.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLILKAEGkvESDFFCQLGHFNLLLEDYPKALsAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAFQ 154
Cdd:COG3063     10 EAEEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAI-ALEKALKLDPN---NAEALLNLAELLLELGDYDEALAYLE 83

                           90
                   ....*....|.
gi 1034675123  155 EVLYVDPSFCR 165
Cdd:COG3063     84 RALELDPSALR 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
106-239 5.09e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 5.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  106 LEDYPKALSAYQRYYSLQSDYwknAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAkeiHLRLGLMFKVNTDYES 185
Cdd:COG4785     86 LGDYDLAIADFDQALELDPDL---AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA---YLNRGIALYYLGRYEL 159

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123  186 SLKHFQ--LALVDCNPCTLSNaeiqfhiAHLYETQRKYHSAKEAYEQLLQTENLSA 239
Cdd:COG4785    160 AIADLEkaLELDPNDPERALW-------LYLAERKLDPEKALALLLEDWATAYLLQ 208
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 98-157 7.99e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 7.99e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   98 QLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVL 157
Cdd:COG1729     35 WLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEELI 94
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 99-162 8.22e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 8.22e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034675123   99 LGHFNLLLE--DYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPS 162
Cdd:pfam13432    1 LALARAALRagDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
104-234 1.17e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 42.18  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  104 LLLEDYPKALSAYQryYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFcRAKEIHLRLGLMFKVNTDY 183
Cdd:COG4700    100 LELGRYDEAIELYE--EALTGIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDF-KSSDAHLLYARALEALGDL 176

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034675123  184 ESSLKHFQLALVdcnpcTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQT 234
Cdd:COG4700    177 EAAEAELEALAR-----RYSGPEARYRYAKFLARQGRTAEAKELLEEILDE 222
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
169-282 1.21e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  169 IHLRLGlmfkvntDYESSLKHFQLALvDCNPctlSNAEIQFHIAHLYETQRKYHSAkEAYEQLLQTENLSAQVkatvLQQ 248
Cdd:COG3063      1 LYLKLG-------DLEEAEEYYEKAL-ELDP---DNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEA----LLN 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 1034675123  249 LGWMHHtvdLLGDKATkesyAIQYLQKSLEADPN 282
Cdd:COG3063     65 LAELLL---ELGDYDE----ALAYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 73-216 1.25e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.06  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   73 LGKAVRCYESLILKAEGKVEsdFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKA 152
Cdd:COG3914    128 LEEALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPD---NAEALNNLGNALQDLGRLEEAIAA 202

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034675123  153 FQEVLYVDPSFCRAkeIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNaeiqFHIAHLYE 216
Cdd:COG3914    203 YRRALELDPDNADA--HSNLLFALRQACDWEVYDRFEELLAALARGPSELSP----FALLYLPD 260
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 218-313 1.50e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.59  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  218 QRKYHSAKEAYEQLLQtENLSAQVKATVLQQLGWMHHtvdLLGDKATkesyAIQYLQKSLEADPNS---GQSWYFLGRCY 294
Cdd:COG1729      6 AGDYDEAIAAFKAFLK-RYPNSPLAPDALYWLGEAYY---ALGDYDE----AAEAFEKLLKRYPDSpkaPDALLKLGLSY 77

                           90
                   ....*....|....*....
gi 1034675123  295 SSIGKVQDAFISYRQSIDK 313
Cdd:COG1729     78 LELGDYDKARATLEELIKK 96
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 75-161 1.83e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123   75 KAVRCYESLI-LKAEgkvESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDywkNAAFLYGLGLVYFHYNAFQWAIKAF 153
Cdd:COG4235     35 EALAAYEKALrLDPD---NADALLDLAEALLAAGDTEEAEELLERALALDPD---NPEALYLLGLAAFQQGDYAEAIAAW 108


                   ....*...
gi 1034675123  154 QEVLYVDP 161
Cdd:COG4235    109 QKLLALLP 116
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 182-283 2.55e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  182 DYESSLKHFQlALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVkATVLQQLGWMHHTvdlLGD 261
Cdd:COG1729      8 DYDEAIAAFK-AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKA-PDALLKLGLSYLE---LGD 82

                           90       100
                   ....*....|....*....|..
gi 1034675123  262 KATkesyAIQYLQKSLEADPNS 283
Cdd:COG1729     83 YDK----ARATLEELIKKYPDS 100
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 130-163 4.24e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 4.24e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 1034675123   130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSF 163
Cdd:smart00028    1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 170-234 4.88e-03

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 40.80  E-value: 4.88e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034675123  170 HLRLGLMFK-VNTDYESSLKHFQLALVDCNPCTLS--NAE---IQFHIAHLYEtqrKYHSAKEAYEQLLQT 234
Cdd:cd24145     10 ILRKALYYEsDKPDPQKALKYYKEALEQADELGMDpfSDEvtgIRIKIAEMLE---KLGMYKAAYEVLERL 77
TPR COG0790
TPR repeat [General function prediction only];
205-364 5.04e-03

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 40.30  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  205 AEIQFHIAHLYE----TQRKYHSAKEAYEQLLQTENLSAQVkatvlqQLGWMHHTvdllGdKATKESY--AIQYLQKSle 278
Cdd:COG0790     63 AEAQYNLGLMYAegrgVPKDYEKALEWFEKAAEQGDAEAQY------NLGLMYEE----G-LGVPQDYakALEWYEKA-- 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034675123  279 ADPNSGQSWYFLGRCYSS-IGKVQD---AFISYRQSIDKSEASADTwcSIGVLYQQ-QNQPMD---ALQAYICAVqlDHG 350
Cdd:COG0790    130 AEQGDADAQYNLGLLYLNgEGVPKDpakAAEWYRKAAEQGDADAQY--NLGVLYENgRGVPKDpakALEWYRKAA--EQG 205

                          170
                   ....*....|....
gi 1034675123  351 HAAAWMDLGTLYES 364
Cdd:COG0790    206 DADAQYNLGRLYLN 219
TPR_17 pfam13431
Tetratricopeptide repeat;
272-303 5.33e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.98  E-value: 5.33e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1034675123  272 YLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 303
Cdd:pfam13431    1 LYLKALELDPNNADAYYNLAVLLLELGQSETA 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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