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Conserved domains on  [gi|1039789995|ref|XP_017168320|]
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polycystin-1-like protein 3 isoform X12 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLAT_polycystin cd01752
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane ...
 1151-1269 1.16e-56

PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological functions remain poorly defined. In human, mutations in polycystin-1 (PKD1) and polycystin-2 (PKD2) have been shown to be the cause for autosomal dominant polycystic kidney disease (ADPKD). The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins.


:

Pssm-ID: 238850  Cd Length: 120  Bit Score: 191.72  E-value: 1.16e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWY 1230
Cdd:cd01752      2 LYLVTVFTGWRRGAGTTAKVTITLYGAEGESEPHHLRDPEKPIFERGSVDSFLLTTPFPLGELQSIRLWHDNSGLSPSWY 81

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1231 VSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPA 1269
Cdd:cd01752     82 LSRVIVRDLQTGKKWFFLCNDWLSVEEGDGTVERTFPVA 120
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 325-652 2.11e-21

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 101.53  E-value: 2.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  325 PASSSPpqVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSP-PQGTSETPASNSP-PQGTSET 402
Cdd:pfam05109  461 PASTGP--TVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPtPNATSPTPAVTTPtPNATSPT 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  403 PGFSSPPQ-VTTATLVSSSP-PQVTSETPASSSPT--------QVTSETPASSSPTqVTSDTPASNSPPQ---GTSDTPG 469
Cdd:pfam05109  539 LGKTSPTSaVTTPTPNATSPtPAVTTPTPNATIPTlgktsptsAVTTPTPNATSPT-VGETSPQANTTNHtlgGTSSTPV 617

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASS 549
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTS 697

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  550 SPPQVTSETPASSSPTNmtSDTPASSSPTNMTSDTPasssPTNMTS-DTPASSSPPWPVITEVTRPESTIPAGRSLANIT 628
Cdd:pfam05109  698 SPAPRPGTTSQASGPGN--SSTSTKPGEVNVTKGTP----PKNATSpQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHG 771

                          330       340
                   ....*....|....*....|....*.
gi 1039789995  629 SKAQED--SPLGVISTHPQMSFQSST 652
Cdd:pfam05109  772 ARTSTEptTDYGGDSTTPRTRYNATT 797
CLECT cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type ...
 37-142 3.21e-07

C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type lectin-like (CTLD) domain; protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins. This group is chiefly comprised of eukaryotic CTLDs, but contains some, as yet functionally uncharacterized, bacterial CTLDs. Many CTLDs are calcium-dependent carbohydrate binding modules; other CTLDs bind protein ligands, lipids, and inorganic surfaces, including CaCO3 and ice. Animal C-type lectins are involved in such functions as extracellular matrix organization, endocytosis, complement activation, pathogen recognition, and cell-cell interactions. For example: mannose-binding lectin and lung surfactant proteins A and D bind carbohydrates on surfaces (e.g. pathogens, allergens, necrotic, and apoptotic cells) and mediate functions associated with killing and phagocytosis; P (platlet)-, E (endothelial)-, and L (leukocyte)- selectins (sels) mediate the initial attachment, tethering, and rolling of lymphocytes on inflamed vascular walls enabling subsequent lymphocyte adhesion and transmigration. CTLDs may bind a variety of carbohydrate ligands including mannose, N-acetylglucosamine, galactose, N-acetylgalactosamine, and fucose. Several CTLDs bind to protein ligands, and only some of these binding interactions are Ca2+-dependent; including the CTLDs of Coagulation Factors IX/X (IX/X) and Von Willebrand Factor (VWF) binding proteins, and natural killer cell receptors. C-type lectins, such as lithostathine, and some type II antifreeze glycoproteins function in a Ca2+-independent manner to bind inorganic surfaces. Many proteins in this group contain a single CTLD; these CTLDs associate with each other through several different surfaces to form dimers, trimers, or tetramers, from which ligand-binding sites project in different orientations. Various vertebrate type 1 transmembrane proteins including macrophage mannose receptor, endo180, phospholipase A2 receptor, and dendritic and epithelial cell receptor (DEC205) have extracellular domains containing 8 or more CTLDs; these CTLDs remain in the parent model. In some members (IX/X and VWF binding proteins), a loop extends to the adjoining domain to form a loop-swapped dimer. A similar conformation is seen in the macrophage mannose receptor CRD4's putative non-sugar bound form of the domain in the acid environment of the endosome. Lineage specific expansions of CTLDs have occurred in several animal lineages including Drosophila melanogaster and Caenorhabditis elegans; these CTLDs also remain in the parent model.


:

Pssm-ID: 153057 [Multi-domain]  Cd Length: 116  Bit Score: 50.31  E-value: 3.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995   37 SCYQLNRLFCDFQEADNYCHAQRGRLAHTWNPKLRGFLKSFL---NEETVW-------------WVRGNLTLPGSHPGIN 100
Cdd:cd00037      1 SCYKFSTEKLTWEEAQEYCRSLGGHLASIHSEEENDFLASLLkksSSSDVWiglndlssegtwkWSDGSPLVDYTNWAPG 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  101 QTGGDDvlrnqkPGECpsvVTHSNAVFSRWN--LCIEKHHFICQ 142
Cdd:cd00037     81 EPNPGG------SEDC---VVLSSSSDGKWNdvSCSSKLPFICE 115
GPS pfam01825
GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for ...
 1041-1079 7.63e-07

GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for auto-proteolysis, so is thus named, GPS. The GPS motif is a conserved sequence of ~40 amino acids containing canonical cysteine and tryptophan residues, and is the most highly conserved part of the domain. In most, if not all, cell-adhesion GPCRs these undergo autoproteolysis in the GPS between a conserved aliphatic residue (usually a leucine) and a threonine, serine, or cysteine residue. In higher eukaryotes this motif is found embedded in the C-terminal beta-stranded part of a GAIN domain - GPCR-Autoproteolysis INducing (GAIN). The GAIN-GPS domain adopts a fold in which the GPS motif, at the C-terminus, forms five beta-strands that are tightly integrated into the overall GAIN domain. The GPS motif, evolutionarily conserved from tetrahymena to mammals, is the only extracellular domain shared by all human cell-adhesion GPCRs and PKD proteins, and is the locus of multiple human disease mutations. The GAIN-GPS domain is both necessary and sufficient functionally for autoproteolysis, suggesting an autoproteolytic mechanism whereby the overall GAIN domain fine-tunes the chemical environment in the GPS to catalyze peptide bond hydrolysis. In the cell-adhesion GPCRs and PKD proteins, the GPS motif is always located at the end of their long N-terminal extracellular regions, immediately before the first transmembrane helix of the respective protein.


:

Pssm-ID: 460350  Cd Length: 44  Bit Score: 46.92  E-value: 7.63e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1039789995 1041 QCYFWDRYNRT---WKSDGCQVGPKSTiLKTQCLCDHLTFFS 1079
Cdd:pfam01825    2 QCVFWDFTNSTtgrWSTEGCTTVSLND-THTVCSCNHLTSFA 42
Chi1 super family cl43877
Chitinase [Carbohydrate transport and metabolism];
224-422 1.08e-05

Chitinase [Carbohydrate transport and metabolism];


The actual alignment was detected with superfamily member COG3469:

Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 49.75  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  224 TGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSS 303
Cdd:COG3469     12 AGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  304 PPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSS--SSPPQGTSDTPASSS 381
Cdd:COG3469     92 TSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSgtETATGGTTTTSTTTT 171

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1039789995  382 PPQGTSETPASNSPPQGTSETPGFSSPP-QVTTATLVSSSPP 422
Cdd:COG3469    172 TTSASTTPSATTTATATTASGATTPSATtTATTTGPPTPGLP 213
 
Name Accession Description Interval E-value
PLAT_polycystin cd01752
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane ...
 1151-1269 1.16e-56

PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological functions remain poorly defined. In human, mutations in polycystin-1 (PKD1) and polycystin-2 (PKD2) have been shown to be the cause for autosomal dominant polycystic kidney disease (ADPKD). The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins.


Pssm-ID: 238850  Cd Length: 120  Bit Score: 191.72  E-value: 1.16e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWY 1230
Cdd:cd01752      2 LYLVTVFTGWRRGAGTTAKVTITLYGAEGESEPHHLRDPEKPIFERGSVDSFLLTTPFPLGELQSIRLWHDNSGLSPSWY 81

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1231 VSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPA 1269
Cdd:cd01752     82 LSRVIVRDLQTGKKWFFLCNDWLSVEEGDGTVERTFPVA 120
PLAT pfam01477
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ...
 1152-1267 3.97e-23

PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich.


Pssm-ID: 396180  Cd Length: 115  Bit Score: 95.58  E-value: 3.97e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1152 YLIQVYTGYRRRAATTAKVVITLYGSEGHS--EPHHLCDPEktvFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSW 1229
Cdd:pfam01477    1 YQVKVVTGDELGAGTDADVYISLYGKVGESaqLEITLDNPD---FERGAEDSFEIDTDWDVGAILKINLHWDNNGLSDEW 77

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1230 YVSQVIV-SDMTTRKKWHFQCNCWLAVDLGNcERDRVFT 1267
Cdd:pfam01477   78 FLKSITVeVPGETGGKYTFPCNSWVYGSKKY-KETRVFF 115
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 325-652 2.11e-21

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 101.53  E-value: 2.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  325 PASSSPpqVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSP-PQGTSETPASNSP-PQGTSET 402
Cdd:pfam05109  461 PASTGP--TVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPtPNATSPTPAVTTPtPNATSPT 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  403 PGFSSPPQ-VTTATLVSSSP-PQVTSETPASSSPT--------QVTSETPASSSPTqVTSDTPASNSPPQ---GTSDTPG 469
Cdd:pfam05109  539 LGKTSPTSaVTTPTPNATSPtPAVTTPTPNATIPTlgktsptsAVTTPTPNATSPT-VGETSPQANTTNHtlgGTSSTPV 617

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASS 549
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTS 697

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  550 SPPQVTSETPASSSPTNmtSDTPASSSPTNMTSDTPasssPTNMTS-DTPASSSPPWPVITEVTRPESTIPAGRSLANIT 628
Cdd:pfam05109  698 SPAPRPGTTSQASGPGN--SSTSTKPGEVNVTKGTP----PKNATSpQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHG 771

                          330       340
                   ....*....|....*....|....*.
gi 1039789995  629 SKAQED--SPLGVISTHPQMSFQSST 652
Cdd:pfam05109  772 ARTSTEptTDYGGDSTTPRTRYNATT 797
PHA03247 PHA03247
large tegument protein UL36; Provisional
 139-661 4.23e-21

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 101.17  E-value: 4.23e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  139 FICQAAAFPPQGASIWRNEFGPGPllPMKRRGAETERHMI------PGNGPPLAMCHQPAPPELFETLCFPIDPASSAPP 212
Cdd:PHA03247  2454 FFARTILGAPFSLSLLLGELFPGA--PVYRRPAEARFPFAagaapdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHP 2531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  213 kathRMtITSLTGRPQVTSDTLASSSPPQGTSDTPA----SSSPPQVTSATSASSSPPQGTS-DTPASSSPPQVTSATSA 287
Cdd:PHA03247  2532 ----RM-LTWIRGLEELASDDAGDPPPPLPPAAPPAapdrSVPPPRPAPRPSEPAVTSRARRpDAPPQSARPRAPVDDRG 2606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  288 SSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSP----PQGTSDTPASSSPPQGTLD- 362
Cdd:PHA03247  2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrprrARRLGRAAQASSPPQRPRRr 2686

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 ---------TPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSP-----PQVTSET 428
Cdd:PHA03247  2687 aarptvgslTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparPPTTAGP 2766

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSP----PQVTSDTPASSSPPQVTS 504
Cdd:PHA03247  2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPagplPPPTSAQPTAPPPPPGPP 2846

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 DTP-------------ASSSPPQVTSETPASSSPPQVTSDTSASISPP----------QVISDTPASSSPPQVTSETPAS 561
Cdd:PHA03247  2847 PPSlplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRStesfalppdqPERPPQPQAPPPPQPQPQPPPP 2926

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  562 SSPTNMTSDTPASSSPTNMTSDTPASSSPtnmtsdtpaSSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVIS 641
Cdd:PHA03247  2927 PQPQPPPPPPPRPQPPLAPTTDPAGAGEP---------SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLT 2997

                          570       580
                   ....*....|....*....|
gi 1039789995  642 THPQMSFQSSTSQQALDETA 661
Cdd:PHA03247  2998 GHSLSRVSSWASSLALHEET 3017
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
373-609 8.77e-14

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 75.94  E-value: 8.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  373 TSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTS 452
Cdd:COG3469      1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  453 DTPASNSPPqgtsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPpqVTSDT 532
Cdd:COG3469     81 TATAAAAAA---------TSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSA--GSTTT 149

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  533 SASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSsptnmtsdTPASSSPPWPVIT 609
Cdd:COG3469    150 TTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTT--------GPPTPGLPKHVLV 218
LH2 smart00308
Lipoxygenase homology 2 (beta barrel) domain;
1151-1256 3.20e-12

Lipoxygenase homology 2 (beta barrel) domain;


Pssm-ID: 214608 [Multi-domain]  Cd Length: 105  Bit Score: 64.20  E-value: 3.20e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNsgDSPSWY 1230
Cdd:smart00308    2 KYKVTVTTGGLDFAGTTASVSLSLVGAEGDGKESKLDYLFKGIFARGSTYEFTFDVDEDFGELGAVKIKNEH--RHPEWF 79

                            90       100
                    ....*....|....*....|....*.
gi 1039789995  1231 VSQVIVSDMTTRKKWHFQCNCWLAVD 1256
Cdd:smart00308   80 LKSITVKDLPTGGKYHFPCNSWVYPD 105
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 347-677 9.73e-09

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 60.39  E-value: 9.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSPPQGTS------DTPassSPPQGTSE----TPASNSPPQGT------SETPgfSSPPQ 410
Cdd:TIGR00927   76 SSDPPKSSSEMEGEMLAPQATVGRDEATpsiameNTP---SPPRRTAKitptTPKNNYSPTAAgtervkEDTP--ATPSR 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  411 VTTATLVSSSPPQVTSETPA------SSSPTQVTSE----TPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTAT 480
Cdd:TIGR00927  151 ALNHYISTSGRQRVKSYTPKprgevkSSSPTQTREKvrkyTPSPLGRMVNSYAPSTFMTMPRSHGITPRTTVKDSEITAT 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 --LVSSSPPQ----VTSDTP----ASSSPPQVTSDTPASS-SPPQVTSETPASSSPPQVTSDTSA---------SISPPQ 540
Cdd:TIGR00927  231 ykMLETNPSKrtagKTTPTPlkgmTDNTPTFLTREVETDLlTSPRSVVEKNTLTTPRRVESNSSTnhwglvgknNLTTPQ 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  541 --VISDTPASSSPpQVTSETPASSSPTnmtsDTPASSSPTNMTSDTPASSSPTNMTsdtpaSSSPPWPVITEVTRPESTI 618
Cdd:TIGR00927  311 gtVLEHTPATSEG-QVTISIMTGSSPA----ETKASTAAWKIRNPLSRTSAPAVRI-----ASATFRGLEKNPSTAPSTP 380

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  619 PAGRSLANITSKAQE---DSPLGVISTHPQMSFQSSTSQQALDETAGERVPTIPDFQAHSEF 677
Cdd:TIGR00927  381 ATPRVRAVLTTQVHHcvvVKPAPAVPTTPSPSLTTALFPEAPSPSPSALPPGQPDLHPKAEY 442
CLECT cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type ...
 37-142 3.21e-07

C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type lectin-like (CTLD) domain; protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins. This group is chiefly comprised of eukaryotic CTLDs, but contains some, as yet functionally uncharacterized, bacterial CTLDs. Many CTLDs are calcium-dependent carbohydrate binding modules; other CTLDs bind protein ligands, lipids, and inorganic surfaces, including CaCO3 and ice. Animal C-type lectins are involved in such functions as extracellular matrix organization, endocytosis, complement activation, pathogen recognition, and cell-cell interactions. For example: mannose-binding lectin and lung surfactant proteins A and D bind carbohydrates on surfaces (e.g. pathogens, allergens, necrotic, and apoptotic cells) and mediate functions associated with killing and phagocytosis; P (platlet)-, E (endothelial)-, and L (leukocyte)- selectins (sels) mediate the initial attachment, tethering, and rolling of lymphocytes on inflamed vascular walls enabling subsequent lymphocyte adhesion and transmigration. CTLDs may bind a variety of carbohydrate ligands including mannose, N-acetylglucosamine, galactose, N-acetylgalactosamine, and fucose. Several CTLDs bind to protein ligands, and only some of these binding interactions are Ca2+-dependent; including the CTLDs of Coagulation Factors IX/X (IX/X) and Von Willebrand Factor (VWF) binding proteins, and natural killer cell receptors. C-type lectins, such as lithostathine, and some type II antifreeze glycoproteins function in a Ca2+-independent manner to bind inorganic surfaces. Many proteins in this group contain a single CTLD; these CTLDs associate with each other through several different surfaces to form dimers, trimers, or tetramers, from which ligand-binding sites project in different orientations. Various vertebrate type 1 transmembrane proteins including macrophage mannose receptor, endo180, phospholipase A2 receptor, and dendritic and epithelial cell receptor (DEC205) have extracellular domains containing 8 or more CTLDs; these CTLDs remain in the parent model. In some members (IX/X and VWF binding proteins), a loop extends to the adjoining domain to form a loop-swapped dimer. A similar conformation is seen in the macrophage mannose receptor CRD4's putative non-sugar bound form of the domain in the acid environment of the endosome. Lineage specific expansions of CTLDs have occurred in several animal lineages including Drosophila melanogaster and Caenorhabditis elegans; these CTLDs also remain in the parent model.


Pssm-ID: 153057 [Multi-domain]  Cd Length: 116  Bit Score: 50.31  E-value: 3.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995   37 SCYQLNRLFCDFQEADNYCHAQRGRLAHTWNPKLRGFLKSFL---NEETVW-------------WVRGNLTLPGSHPGIN 100
Cdd:cd00037      1 SCYKFSTEKLTWEEAQEYCRSLGGHLASIHSEEENDFLASLLkksSSSDVWiglndlssegtwkWSDGSPLVDYTNWAPG 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  101 QTGGDDvlrnqkPGECpsvVTHSNAVFSRWN--LCIEKHHFICQ 142
Cdd:cd00037     81 EPNPGG------SEDC---VVLSSSSDGKWNdvSCSSKLPFICE 115
GPS pfam01825
GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for ...
 1041-1079 7.63e-07

GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for auto-proteolysis, so is thus named, GPS. The GPS motif is a conserved sequence of ~40 amino acids containing canonical cysteine and tryptophan residues, and is the most highly conserved part of the domain. In most, if not all, cell-adhesion GPCRs these undergo autoproteolysis in the GPS between a conserved aliphatic residue (usually a leucine) and a threonine, serine, or cysteine residue. In higher eukaryotes this motif is found embedded in the C-terminal beta-stranded part of a GAIN domain - GPCR-Autoproteolysis INducing (GAIN). The GAIN-GPS domain adopts a fold in which the GPS motif, at the C-terminus, forms five beta-strands that are tightly integrated into the overall GAIN domain. The GPS motif, evolutionarily conserved from tetrahymena to mammals, is the only extracellular domain shared by all human cell-adhesion GPCRs and PKD proteins, and is the locus of multiple human disease mutations. The GAIN-GPS domain is both necessary and sufficient functionally for autoproteolysis, suggesting an autoproteolytic mechanism whereby the overall GAIN domain fine-tunes the chemical environment in the GPS to catalyze peptide bond hydrolysis. In the cell-adhesion GPCRs and PKD proteins, the GPS motif is always located at the end of their long N-terminal extracellular regions, immediately before the first transmembrane helix of the respective protein.


Pssm-ID: 460350  Cd Length: 44  Bit Score: 46.92  E-value: 7.63e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1039789995 1041 QCYFWDRYNRT---WKSDGCQVGPKSTiLKTQCLCDHLTFFS 1079
Cdd:pfam01825    2 QCVFWDFTNSTtgrWSTEGCTTVSLND-THTVCSCNHLTSFA 42
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 240-589 1.53e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 52.99  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  240 PQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQ 319
Cdd:NF033609   558 PEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  320 GTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGT 399
Cdd:NF033609   638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 717

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  400 SETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPA-SNSPPQGTSDTPGFSSPTQVTT 478
Cdd:NF033609   718 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSD 797

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSET 558
Cdd:NF033609   798 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNS 877

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1039789995  559 PASSSPTNMTSDTPASSSPTNMT-SDTPASSS 589
Cdd:NF033609   878 PKNGTNASNKNEAKDSKEPLPDTgSEDEANTS 909
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 270-603 8.17e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 50.68  E-value: 8.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  270 SDT-PASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTS 348
Cdd:NF033609   561 SDSdPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 640

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  349 DTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSET 428
Cdd:NF033609   641 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 720

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PA-SSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTP 507
Cdd:NF033609   721 DSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 800

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  508 ASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPAS 587
Cdd:NF033609   801 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSPKN 880

                          330
                   ....*....|....*.
gi 1039789995  588 SSPTNMTSDTPASSSP 603
Cdd:NF033609   881 GTNASNKNEAKDSKEP 896
GPS smart00303
G-protein-coupled receptor proteolytic site domain; Present in latrophilin/CL-1, sea urchin ...
 1040-1079 9.85e-06

G-protein-coupled receptor proteolytic site domain; Present in latrophilin/CL-1, sea urchin REJ and polycystin.


Pssm-ID: 197639  Cd Length: 49  Bit Score: 43.92  E-value: 9.85e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 1039789995  1040 TQCYFWDRYNRTWKSDGCQVGPKS-TIlkTQCLCDHLTFFS 1079
Cdd:smart00303    3 PICVFWDESSGEWSTRGCELLETNgTH--TTCSCNHLTTFA 41
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
224-422 1.08e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 49.75  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  224 TGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSS 303
Cdd:COG3469     12 AGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  304 PPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSS--SSPPQGTSDTPASSS 381
Cdd:COG3469     92 TSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSgtETATGGTTTTSTTTT 171

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1039789995  382 PPQGTSETPASNSPPQGTSETPGFSSPP-QVTTATLVSSSPP 422
Cdd:COG3469    172 TTSASTTPSATTTATATTASGATTPSATtTATTTGPPTPGLP 213
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 349-601 1.39e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.91  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  349 DTPASSSPPqgtlDTPSSSSP-PQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSE 427
Cdd:NF033609   540 DKPVVPEQP----DEPGEIEPiPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASD 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPTQVTSDtpaSNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTP 507
Cdd:NF033609   616 SDSASDSDSASDSDSASDSDSASDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  508 ASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASS-SPTNMTSDTPA 586
Cdd:NF033609   693 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDS 772

                          250
                   ....*....|....*.
gi 1039789995  587 -SSSPTNMTSDTPASS 601
Cdd:NF033609   773 dSDSDSDSDSDSDSDS 788
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 439-631 1.94e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.52  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  439 SETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQvtSDTPASSSPPQVTSE 518
Cdd:NF033609    33 SSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVAQNPAQ--QETTQSASTNATTEE 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  519 TPASSSPPQVTSDTSASISPPQViSDTPASSSPPQVTSETpaSSSPTNMTSDTpasSSPTN--------MTSDTPASSSP 590
Cdd:NF033609   111 TPVTGEATTTATNQANTPATTQS-SNTNAEELVNQTSNET--TSNDTNTVSSV---NSPQNstnaenvsTTQDTSTEATP 184

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1039789995  591 TNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKA 631
Cdd:NF033609   185 SNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADA 225
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 231-576 1.80e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.06  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  231 SDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSA 310
Cdd:NF033609   571 SDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDS 650

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  311 TSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETP 390
Cdd:NF033609   651 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 730

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  391 ASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPA-SNSPPQGTSDTPG 469
Cdd:NF033609   731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDS 810

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSppqvtSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPqvisDTPASS 549
Cdd:NF033609   811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPP----NSPKNG 881

                          330       340
                   ....*....|....*....|....*...
gi 1039789995  550 SPPQVTSETPASSSPTNMT-SDTPASSS 576
Cdd:NF033609   882 TNASNKNEAKDSKEPLPDTgSEDEANTS 909
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 204-410 5.84e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  204 IDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQvts 283
Cdd:PRK07764   588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD--- 664

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  284 atSASSSPPQGTSDTPASSSPPQVTsatsasssppqGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDT 363
Cdd:PRK07764   665 --GGDGWPAKAGGAAPAAPPPAPAP-----------AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAP 731

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSS---PPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQ 410
Cdd:PRK07764   732 SPAADdpvPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
SP2_N cd22540
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins ...
 351-604 7.31e-04

N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP2 contains the least conserved DNA-binding domain within the SP subfamily of proteins, and its DNA sequence specificity differs from the other SP proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate, or in some cases, repress expression from different promoters. The transcription factor SP2 serves as a paradigm for indirect genomic binding. It does not require its DNA-binding domain for genomic DNA binding and occupies target promoters independently of whether they contain a cognate DNA-binding motif. SP2 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP2.


Pssm-ID: 411776 [Multi-domain]  Cd Length: 511  Bit Score: 43.76  E-value: 7.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSS------PPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSS---- 420
Cdd:cd22540     66 PLPLGPGKNSIGFLSAKGniiqlqGSQLSSSAPGGQQVFAIQNPTMIIKGSQTRSSTNQQYQISPQIQAAGQINNSgqiq 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  421 -----------PPQVTSETPASSSPTQV---------TSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTAT 480
Cdd:cd22540    146 iipgtnqaiitPVQVLQQPQQAHKPVPIkpaplqtsnTNSASLQVPGNVIKLQSGGNVALTLPVNNLVGTQDGATQLQLA 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 LVSSSPPQVTSDTPASSSPPQVTS--------------------------DTPASSSPPQV--------TSETPASSSPP 526
Cdd:cd22540    226 AAPSKPSKKIRKKSAQAAQPAVTVaeqvetvliettadniiqagnnllivQSPGTGQPAVLqqvqvlqpKQEQQVVQIPQ 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  527 ------QVTSDTSASI--SPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTP 598
Cdd:cd22540    306 qalrvvQAASATLPTVpqKPLQNIQIQNSEPTPTQVYIKTPSGEVQTVLLQEAPAATATPSSSTSTVQQQVTANNGTGTS 385


                   ....*.
gi 1039789995  599 ASSSPP 604
Cdd:cd22540    386 KPNYNV 391
CLECT smart00034
C-type lectin (CTL) or carbohydrate-recognition domain (CRD); Many of these domains function ...
 35-142 3.80e-03

C-type lectin (CTL) or carbohydrate-recognition domain (CRD); Many of these domains function as calcium-dependent carbohydrate binding modules.


Pssm-ID: 214480 [Multi-domain]  Cd Length: 124  Bit Score: 38.73  E-value: 3.80e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995    35 GNSCYQLNRLFCDFQEADNYCHAQRGRLA-------HTWnpkLRGFLKSFLNEETVW------WVRGNLTlpgshpGINQ 101
Cdd:smart00034    9 GGKCYKFSTEKKTWEDAQAFCQSLGGHLAsihseaeNDF---VASLLKNSGSSDYYWiglsdpDSNGSWQ------WSDG 79

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|....*..
gi 1039789995   102 TGGDDVLrNQKPGEcPSVVTHSNAVFS----RWNL--CIEKHHFICQ 142
Cdd:smart00034   80 SGPVSYS-NWAPGE-PNNSSGDCVVLStsggKWNDvsCTSKLPFVCE 124
 
Name Accession Description Interval E-value
PLAT_polycystin cd01752
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane ...
 1151-1269 1.16e-56

PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological functions remain poorly defined. In human, mutations in polycystin-1 (PKD1) and polycystin-2 (PKD2) have been shown to be the cause for autosomal dominant polycystic kidney disease (ADPKD). The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins.


Pssm-ID: 238850  Cd Length: 120  Bit Score: 191.72  E-value: 1.16e-56
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWY 1230
Cdd:cd01752      2 LYLVTVFTGWRRGAGTTAKVTITLYGAEGESEPHHLRDPEKPIFERGSVDSFLLTTPFPLGELQSIRLWHDNSGLSPSWY 81

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1231 VSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPA 1269
Cdd:cd01752     82 LSRVIVRDLQTGKKWFFLCNDWLSVEEGDGTVERTFPVA 120
PLAT_repeat cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 ...
 1152-1269 3.73e-29

PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins.


Pssm-ID: 238854  Cd Length: 120  Bit Score: 113.03  E-value: 3.73e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1152 YLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTV-FERGALDVFLLSTGSwLGDLHGLRLWHDNSGDSPSWY 1230
Cdd:cd01756      3 YEVTVKTGDVKGAGTDANVFITLYGENGDTGKRKLKKSNNKNkFERGQTDKFTVEAVD-LGKLKKIRIGHDNSGLGAGWF 81

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1231 VSQVIVSDMTTRKKWHFQCNCWLAVDLGNCERDRVFTPA 1269
Cdd:cd01756     82 LDKVEIREPGTGDEYTFPCNRWLDKDEDDGQIVRELYPS 120
PLAT pfam01477
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ...
 1152-1267 3.97e-23

PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich.


Pssm-ID: 396180  Cd Length: 115  Bit Score: 95.58  E-value: 3.97e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1152 YLIQVYTGYRRRAATTAKVVITLYGSEGHS--EPHHLCDPEktvFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSW 1229
Cdd:pfam01477    1 YQVKVVTGDELGAGTDADVYISLYGKVGESaqLEITLDNPD---FERGAEDSFEIDTDWDVGAILKINLHWDNNGLSDEW 77

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995 1230 YVSQVIV-SDMTTRKKWHFQCNCWLAVDLGNcERDRVFT 1267
Cdd:pfam01477   78 FLKSITVeVPGETGGKYTFPCNSWVYGSKKY-KETRVFF 115
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 325-652 2.11e-21

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 101.53  E-value: 2.11e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  325 PASSSPpqVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSP-PQGTSETPASNSP-PQGTSET 402
Cdd:pfam05109  461 PASTGP--TVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPtPNATSPTPAVTTPtPNATSPT 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  403 PGFSSPPQ-VTTATLVSSSP-PQVTSETPASSSPT--------QVTSETPASSSPTqVTSDTPASNSPPQ---GTSDTPG 469
Cdd:pfam05109  539 LGKTSPTSaVTTPTPNATSPtPAVTTPTPNATIPTlgktsptsAVTTPTPNATSPT-VGETSPQANTTNHtlgGTSSTPV 617

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASS 549
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTS 697

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  550 SPPQVTSETPASSSPTNmtSDTPASSSPTNMTSDTPasssPTNMTS-DTPASSSPPWPVITEVTRPESTIPAGRSLANIT 628
Cdd:pfam05109  698 SPAPRPGTTSQASGPGN--SSTSTKPGEVNVTKGTP----PKNATSpQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHG 771

                          330       340
                   ....*....|....*....|....*.
gi 1039789995  629 SKAQED--SPLGVISTHPQMSFQSST 652
Cdd:pfam05109  772 ARTSTEptTDYGGDSTTPRTRYNATT 797
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 348-697 2.37e-21

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 101.15  E-value: 2.37e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  348 SDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSP-PQGTSETPGFSSP-PQVTTATLVSSSPPQ-V 424
Cdd:pfam05109  469 STADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPtPNATSPTPAVTTPtPNATSPTLGKTSPTSaV 548

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSETPASSSPT-QVTSETPASSSPT-QVTSDTPASNSP-PQGTSDTPGFSSPTQVTTATLVSSsppqvTSDTPASSSPPQ 501
Cdd:pfam05109  549 TTPTPNATSPTpAVTTPTPNATIPTlGKTSPTSAVTTPtPNATSPTVGETSPQANTTNHTLGG-----TSSTPVVTSPPK 623

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  502 VTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSP-----PQVTSETPASSSPTNMTSDTPASSS 576
Cdd:pfam05109  624 NATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAhptggENITQVTPASTSTHHVSTSSPAPRP 703

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  577 PTNMTSDTPASSSPT------NMTSDTPA--SSSPPWPVITEVTRPESTIPAGRslANITSKAQEDSPLGV-ISTHPQMS 647
Cdd:pfam05109  704 GTTSQASGPGNSSTStkpgevNVTKGTPPknATSPQAPSGQKTAVPTVTSTGGK--ANSTTGGKHTTGHGArTSTEPTTD 781

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039789995  648 FQSSTSQQALDETAGERVPTIPDFQAHSEFQKACAILQRLRDFLPTSPTS 697
Cdd:pfam05109  782 YGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPPVTTAQATVPVPPTS 831
PHA03247 PHA03247
large tegument protein UL36; Provisional
 139-661 4.23e-21

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 101.17  E-value: 4.23e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  139 FICQAAAFPPQGASIWRNEFGPGPllPMKRRGAETERHMI------PGNGPPLAMCHQPAPPELFETLCFPIDPASSAPP 212
Cdd:PHA03247  2454 FFARTILGAPFSLSLLLGELFPGA--PVYRRPAEARFPFAagaapdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHP 2531

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  213 kathRMtITSLTGRPQVTSDTLASSSPPQGTSDTPA----SSSPPQVTSATSASSSPPQGTS-DTPASSSPPQVTSATSA 287
Cdd:PHA03247  2532 ----RM-LTWIRGLEELASDDAGDPPPPLPPAAPPAapdrSVPPPRPAPRPSEPAVTSRARRpDAPPQSARPRAPVDDRG 2606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  288 SSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSP----PQGTSDTPASSSPPQGTLD- 362
Cdd:PHA03247  2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSrprrARRLGRAAQASSPPQRPRRr 2686

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 ---------TPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSP-----PQVTSET 428
Cdd:PHA03247  2687 aarptvgslTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparPPTTAGP 2766

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSP----PQVTSDTPASSSPPQVTS 504
Cdd:PHA03247  2767 PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPagplPPPTSAQPTAPPPPPGPP 2846

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 DTP-------------ASSSPPQVTSETPASSSPPQVTSDTSASISPP----------QVISDTPASSSPPQVTSETPAS 561
Cdd:PHA03247  2847 PPSlplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRStesfalppdqPERPPQPQAPPPPQPQPQPPPP 2926

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  562 SSPTNMTSDTPASSSPTNMTSDTPASSSPtnmtsdtpaSSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVIS 641
Cdd:PHA03247  2927 PQPQPPPPPPPRPQPPLAPTTDPAGAGEP---------SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLT 2997

                          570       580
                   ....*....|....*....|
gi 1039789995  642 THPQMSFQSSTSQQALDETA 661
Cdd:PHA03247  2998 GHSLSRVSSWASSLALHEET 3017
PLAT cd00113
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. ...
 1151-1253 3.78e-19

PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates.


Pssm-ID: 238061  Cd Length: 116  Bit Score: 84.31  E-value: 3.78e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHhLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWY 1230
Cdd:cd00113      2 RYTVTIKTGDKKGAGTDSNISLALYGENGNSSDI-PILDGPGSFERGSTDTFQIDLKLDIGDITKVYLRRDGSGLSDGWY 80

                           90       100
                   ....*....|....*....|...
gi 1039789995 1231 VSQVIVSDMTTRKKWHFQCNCWL 1253
Cdd:cd00113     81 CESITVQALGTKKVYTFPVNRWV 103
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 192-604 9.57e-19

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 92.93  E-value: 9.57e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  192 APPELFETLCFPIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPqvtsATSASSSPPQGTSD 271
Cdd:PHA03307    53 VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP----DPPPPTPPPASPPP 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  272 TPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQG-TSDTPASSSPPQVTSATSASSSPPQGTSdt 350
Cdd:PHA03307   129 SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSsPEETARAPSSPPAEPPPSTPPAAASPRP-- 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSSPPQGTSDTPASSSppqGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPA 430
Cdd:PHA03307   207 PRRSSPISASASSPAPAPGRSAADDAGASSS---DSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPG 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  431 SSSPtqVTSETPASSSPTQVTSDTPASNSPPQGTSDtpGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASS 510
Cdd:PHA03307   284 PASS--SSSPRERSPSPSPSSPGSGPAPSSPRASSS--SSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPP 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  511 SPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSP 590
Cdd:PHA03307   360 ADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEP 439

                          410
                   ....*....|....
gi 1039789995  591 tnmtsdTPASSSPP 604
Cdd:PHA03307   440 ------WPGSPPPP 447
PHA03247 PHA03247
large tegument protein UL36; Provisional
 142-629 3.48e-18

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 91.54  E-value: 3.48e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  142 QAAAFPPQGASIWRNEFGPGPllpmkrRGAETERHMIPGNGPPLAMCHQPAPPELF---ETLCFPIDPASSAPPKATHRM 218
Cdd:PHA03247  2613 PPSPLPPDTHAPDPPPPSPSP------AANEPDPHPPPTVPPPERPRDDPAPGRVSrprRARRLGRAAQASSPPQRPRRR 2686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  219 TItsltgRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSA----SSSPPQG 294
Cdd:PHA03247  2687 AA-----RPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATpggpARPARPP 2761

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  295 TSDTPASSSPPQVtsatsasssppqgtsdtPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPqgtS 374
Cdd:PHA03247  2762 TTAGPPAPAPPAA-----------------PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP---A 2821

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  375 DTPASSSPPQgTSETPASNSPPQG---TSETPGFSSPPqvtTATLVSSSPPQVTSETPASSSPTQVTS-ETPASSSPTQV 450
Cdd:PHA03247  2822 ASPAGPLPPP-TSAQPTAPPPPPGpppPSLPLGGSVAP---GGDVRRRPPSRSPAAKPAAPARPPVRRlARPAVSRSTES 2897

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  451 TSDTPASNSPPQgtsdTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTS 530
Cdd:PHA03247  2898 FALPPDQPERPP----QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVA 2973

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  531 DTSASISPPQVISDTPASSSPPQVTSETP-----ASSSPTNMTSDTPASSSPTNM--TSDTPASSSPTNMTSDTPASSS- 602
Cdd:PHA03247  2974 VPRFRVPQPAPSREAPASSTPPLTGHSLSrvsswASSLALHEETDPPPVSLKQTLwpPDDTEDSDADSLFDSDSERSDLe 3053

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039789995  603 -----PPWPVITEVTRPESTIPAGRSLANITS 629
Cdd:PHA03247  3054 aldplPPEPHDPFAHEPDPATPEAGARESPSS 3085
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 237-636 1.66e-17

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 89.07  E-value: 1.66e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  237 SSPPQGTSDTPASSSPPQVtsatsasssppqGTSDTPASSSPPQVTSATSASSSPPQGtsdtPASSSPPQVTSATSASSS 316
Cdd:PHA03307    25 PATPGDAADDLLSGSQGQL------------VSDSAELAAVTVVAGAAACDRFEPPTG----PPPGPGTEAPANESRSTP 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  317 PPQGTSDTPASSSPPQvtsatsaSSSPPQGTSDTPA-SSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSP 395
Cdd:PHA03307    89 TWSLSTLAPASPAREG-------SPTPPGPSSPDPPpPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  396 PQGTSETPGFSSPP-QVTTATLVSSSPPQvtSETPASSSPTQVTSETPASSSPTQVTSDTPASnSPPQGTSDTPGFSSPT 474
Cdd:PHA03307   162 VASDAASSRQAALPlSSPEETARAPSSPP--AEPPPSTPPAAASPRPPRRSSPISASASSPAP-APGRSAADDAGASSSD 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  475 QVTTATLVSSSPPQvtSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPqVISDTPASSSPPQV 554
Cdd:PHA03307   239 SSSSESSGCGWGPE--NECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPS-SPGSGPAPSSPRAS 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  555 TSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPP--------WPVITEVTRPESTIPAGRSLAN 626
Cdd:PHA03307   316 SSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPrkrprpsrAPSSPAASAGRPTRRRARAAVA 395

                          410
                   ....*....|
gi 1039789995  627 ITSKAQEDSP 636
Cdd:PHA03307   396 GRARRRDATG 405
PHA03247 PHA03247
large tegument protein UL36; Provisional
 190-607 2.32e-17

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 88.84  E-value: 2.32e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  190 QPAPPELFETLCFPIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSasssppqgt 269
Cdd:PHA03247  2704 PPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAA--------- 2774

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  270 sdtPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPpqgTSDTPASSSPPQvtsatsasssppqgTSD 349
Cdd:PHA03247  2775 ---PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP---PAASPAGPLPPP--------------TSA 2834

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  350 TPASSSPPQGtldtPSSSSPPQGTSDTP----ASSSPPQGTSETPASNS-PPQGTSETPGFSSPPQvttaTLVSSSPPQV 424
Cdd:PHA03247  2835 QPTAPPPPPG----PPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPArPPVRRLARPAVSRSTE----SFALPPDQPE 2906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTS 504
Cdd:PHA03247  2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSR 2986

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 DTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDT---PASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMT 581
Cdd:PHA03247  2987 EAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVSLKQTlwpPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPF 3066

                          410       420
                   ....*....|....*....|....*.
gi 1039789995  582 SDTPASSSPTNMTSDTPASSSPPWPV 607
Cdd:PHA03247  3067 AHEPDPATPEAGARESPSSQFGPPPL 3092
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 171-619 2.63e-15

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 81.50  E-value: 2.63e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  171 AETERHMIPGNGPPLAMCHQPAppelFETLCFPIDPASSAPPKATH---RMTITSLTGRPQVTSDTlaSSSPPQGTSDTP 247
Cdd:pfam05109  412 ATTTTHKVIFSKAPESTTTSPT----LNTTGFAAPNTTTGLPSSTHvptNLTAPASTGPTVSTADV--TSPTPAGTTSGA 485

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  248 ASSSPPQVTSATSASSSPPQGTSDTPASSSPpqvtsatsasssPPQGTSDTPASSSPpqvtsatsasssPPQGTSDTPAS 327
Cdd:pfam05109  486 SPVTPSPSPRDNGTESKAPDMTSPTSAVTTP------------TPNATSPTPAVTTP------------TPNATSPTLGK 541

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  328 SSPpqvtsATSASSSPPQGTSDTPASSSP-PQGTLDTPSSSSPPQG-TSDTPASSSPPQGTSETPA--SNSPPQGTSETP 403
Cdd:pfam05109  542 TSP-----TSAVTTPTPNATSPTPAVTTPtPNATIPTLGKTSPTSAvTTPTPNATSPTVGETSPQAntTNHTLGGTSSTP 616

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  404 GFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSsptqvTSDTPASNSPPQGTSDTPGFSSPTQVTTAtlvS 483
Cdd:pfam05109  617 VVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPS-----TSDNSTSHMPLLTSAHPTGGENITQVTPA---S 688

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  484 SSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASS-SPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASS 562
Cdd:pfam05109  689 TSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKgTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTT 768

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  563 SPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVIT-EVTRPESTIP 619
Cdd:pfam05109  769 GHGARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSpPVTTAQATVP 826
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 345-623 5.68e-15

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 79.62  E-value: 5.68e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPASSSPPqgtldTPSSSSPPQGTSDTPASSS-PPQGTSETPASNSPPQGTSETPgfSSPPQVTTATLVSSSPPQ 423
Cdd:pfam17823  104 EGAADGAASRALA-----AAASSSPSSAAQSLPAAIAaLPSEAFSAPRAAACRANASAAP--RAAIAAASAPHAASPAPR 176

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  424 V--------TSETPASSSPTQVTSETPASSSPTQVTSD------TPAS--------NSPPQGTSDTPGFSSPTQVTTATL 481
Cdd:pfam17823  177 TaassttaaSSTTAASSAPTTAASSAPATLTPARGISTaatatgHPAAgtalaavgNSSPAAGTVTAAVGTVTPAALATL 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  482 VSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSasisppQVISDTPASSSPPQVTSeTPAS 561
Cdd:pfam17823  257 AAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPII------QVSTDQPVHNTAGEPTP-SPSN 329

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  562 SSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASS-SPPWPVITEVTRPESTIPAGRS 623
Cdd:pfam17823  330 TTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSmIPEVEATSPTTQPSPLLPTQGA 392
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
373-609 8.77e-14

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 75.94  E-value: 8.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  373 TSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTS 452
Cdd:COG3469      1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  453 DTPASNSPPqgtsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPpqVTSDT 532
Cdd:COG3469     81 TATAAAAAA---------TSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSA--GSTTT 149

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  533 SASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSsptnmtsdTPASSSPPWPVIT 609
Cdd:COG3469    150 TTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTT--------GPPTPGLPKHVLV 218
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 206-564 1.03e-13

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 76.49  E-value: 1.03e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  206 PASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDtpaSSSPPQVTSATSASSSPPQGTSDTPASSSPP------ 279
Cdd:pfam05109  461 PASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTE---SKAPDMTSPTSAVTTPTPNATSPTPAVTTPTpnatsp 537

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  280 ---QVTSATSASSSPPQGTSDTPASSSP-PQVTSATSASSSPPQG-TSDTPASSSPP--QVTSATSASSSPPQGTSDTPA 352
Cdd:pfam05109  538 tlgKTSPTSAVTTPTPNATSPTPAVTTPtPNATIPTLGKTSPTSAvTTPTPNATSPTvgETSPQANTTNHTLGGTSSTPV 617

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  353 SSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSP-----PQVTTATLVSSSPPQVTSE 427
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAhptggENITQVTPASTSTHHVSTS 697

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPT------QVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQ 501
Cdd:pfam05109  698 SPAPRPGTTSQASGPGNSSTStkpgevNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHGARTSTE 777

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  502 VTSDTPASSSPPQvTSETPASSSPPQvtsdTSASISPPQVISDTPASSSppQVTSETPASSSP 564
Cdd:pfam05109  778 PTTDYGGDSTTPR-TRYNATTYLPPS----TSSKLRPRWTFTSPPVTTA--QATVPVPPTSQP 833
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 191-576 1.94e-13

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 75.57  E-value: 1.94e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  191 PAPPELFETLCFPIDPASSAPPKATHRMT--ITSLTGRPQVTSDTLASSSPP--QGTSDTPASSSPPQVTSATSASsspp 266
Cdd:pfam03154  197 AGPTPSAPSVPPQGSPATSQPPNQTQSTAapHTLIQQTPTLHPQRLPSPHPPlqPMTQPPPPSQVSPQPLPQPSLH---- 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  267 qgtSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQvtsatsasssppqg 346
Cdd:pfam03154  273 ---GQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQ-------------- 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 tSDTPASSSP-PQGTLDTPSSSSPPQgtsdTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVT 425
Cdd:pfam03154  336 -SQQPPREQPlPPAPLSMPHIKPPPT----TPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  426 SETPASSSPTQVTSETPASSSP--TQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVT 503
Cdd:pfam03154  411 HPPPLQLMPQSQQLPPPPAQPPvlTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMP 490

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  504 SDTPASSSPPQVTSETPASssppqvtsdTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSS 576
Cdd:pfam03154  491 GIQPPSSASVSSSGPVPAA---------VSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHAS 554
LH2 smart00308
Lipoxygenase homology 2 (beta barrel) domain;
1151-1256 3.20e-12

Lipoxygenase homology 2 (beta barrel) domain;


Pssm-ID: 214608 [Multi-domain]  Cd Length: 105  Bit Score: 64.20  E-value: 3.20e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  1151 HYLIQVYTGYRRRAATTAKVVITLYGSEGHSEPHHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNsgDSPSWY 1230
Cdd:smart00308    2 KYKVTVTTGGLDFAGTTASVSLSLVGAEGDGKESKLDYLFKGIFARGSTYEFTFDVDEDFGELGAVKIKNEH--RHPEWF 79

                            90       100
                    ....*....|....*....|....*.
gi 1039789995  1231 VSQVIVSDMTTRKKWHFQCNCWLAVD 1256
Cdd:smart00308   80 LKSITVKDLPTGGKYHFPCNSWVYPD 105
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 206-578 4.14e-12

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 70.37  E-value: 4.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  206 PASSAPPKATHRMTITSLTGRPQVTSDTLASSSPP--QGTSDTPASSSPpqvtsATSASSSPPQGTSDTPASSSPPQVTS 283
Cdd:pfam17823   67 PAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPAtrEGAADGAASRAL-----AAAASSSPSSAAQSLPAAIAALPSEA 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  284 ATSASSSPPQgtsdTPASSSPpqvtsatsasSSPPQGTSDTPASSSPPQVTSATSASssppqGTSDTPASSSPPQGTLDT 363
Cdd:pfam17823  142 FSAPRAAACR----ANASAAP----------RAAIAAASAPHAASPAPRTAASSTTA-----ASSTTAASSAPTTAASSA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGTSDTPASSSPPQ---GTSETPASNSPPQGTSETPGFSSPPQV-----------TTATLVSSSPPQVTSETP 429
Cdd:pfam17823  203 PATLTPARGISTAATATGHPAagtALAAVGNSSPAAGTVTAAVGTVTPAALatlaaaagtvaSAAGTINMGDPHARRLSP 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  430 ASSSPTQVTSETPASSS-------PTQVTSDTPASNSPPQGTSdTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQV 502
Cdd:pfam17823  283 AKHMPSDTMARNPAAPMgaqaqgpIIQVSTDQPVHNTAGEPTP-SPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSAS 361

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  503 TSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQViSDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPT 578
Cdd:pfam17823  362 PVPVLHTSMIPEVEATSPTTQPSPLLPTQGAAGPGILLA-PEQVATEATAGTASAGPTPRSSGDPKTLAMASCQLS 436
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
351-605 7.07e-12

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 70.26  E-value: 7.07e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQ---VTSE 427
Cdd:PRK07003   362 VTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAtadRGDD 441

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPT-QVTSDTPASNSPPQG--TSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTS 504
Cdd:PRK07003   442 AADGDAPVPAKANARASADSRcDERDAQPPADSGSASapASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDA 521

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 DTPASSSPPQVTSETPASSSPPQVTSDTSASI-----SPPQVISD------TPASSSPPQVTSETPASSSPtnmTSDTPA 573
Cdd:PRK07003   522 PAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnAGMRVSSDrgaraaAAAKPAAAPAAAPKPAAPRV---AVQVPT 598

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1039789995  574 SSSPTNMTSDTPASSSPTNMTSDTPaSSSPPW 605
Cdd:PRK07003   599 PRARAATGDAPPNGAARAEQAAESR-GAPPPW 629
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 211-608 8.99e-12

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 70.18  E-value: 8.99e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  211 PPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTpASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSS 290
Cdd:pfam03154   94 PERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDE-GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQILQTQPP 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  291 PPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPP------QVTSATSASSSPPQGTSDTPASSSPPQGTLDTP 364
Cdd:pfam03154  173 VLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPAtsqppnQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPM 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  365 SSSSPPQGTSDTPASSS------------------------PPQG---TSETPASNSPPQGTSETPGFSSPPQVTTATLV 417
Cdd:pfam03154  253 TQPPPPSQVSPQPLPQPslhgqmppmphslqtgpshmqhpvPPQPfplTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQS 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  418 SSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPgFSSPTQVTT-------ATLVSSSPP--- 487
Cdd:pfam03154  333 QLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSP-FQMNSNLPPppalkplSSLSTHHPPsah 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  488 ----QVTSDTPASSSPP-------QVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTS 556
Cdd:pfam03154  412 ppplQLMPQSQQLPPPPaqppvltQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPG 491

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  557 ETPASSSPTNMTSDTPASSS----PTNMTSDTPASSSPTNMTSDTPASSSPPWPVI 608
Cdd:pfam03154  492 IQPPSSASVSSSGPVPAAVScplpPVQIKEEALDEAEEPESPPPPPRSPSPEPTVV 547
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 232-643 4.90e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 67.70  E-value: 4.90e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  232 DTLASSSPPQGTSDTPASSSPPQvtsatsasssppqgTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSAT 311
Cdd:PRK07764   379 ERLERRLGVAGGAGAPAAAAPSA--------------AAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSP 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  312 SASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPA-SSSPPQ------ 384
Cdd:PRK07764   445 AGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATlRERWPEilaavp 524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  385 -------GTSETPASNSPPQGTSETPGFSSPP------QVTTATLVSSSPPQVTSET----------PASSSPTQVTSET 441
Cdd:PRK07764   525 krsrktwAILLPEATVLGVRGDTLVLGFSTGGlarrfaSPGNAEVLVTALAEELGGDwqveavvgpaPGAAGGEGPPAPA 604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  442 PASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPA 521
Cdd:PRK07764   605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPA 684

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  522 SSSPPQVtsdTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTP---------ASSSPTN 592
Cdd:PRK07764   685 PAPAAPA---APAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPddppdpagaPAQPPPP 761

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  593 MTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVISTH 643
Cdd:PRK07764   762 PAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAMELLEEE 812
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 227-658 3.59e-10

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 64.79  E-value: 3.59e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  227 PQVTSDTLASSSPPQGTSDTPASSSPPqvtsatsaSSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQ 306
Cdd:pfam03154  187 PPPGTTQAATAGPTPSAPSVPPQGSPA--------TSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPP 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  307 vtsatsasssppqgTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGT 386
Cdd:pfam03154  259 --------------SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQR 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  387 SETPASNSPPQgtsetpgfssppqvttatlvsssPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSD 466
Cdd:pfam03154  325 IHTPPSQSQLQ-----------------------SQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGP 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  467 TPgFSSPtqvttatlvSSSPPqvtsdTPASSSPPQVTSDTPASSSPP--QVTSETPASSSPPQVTSDTSASISPPQVISD 544
Cdd:pfam03154  382 SP-FQMN---------SNLPP-----PPALKPLSSLSTHHPPSAHPPplQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAS 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  545 TPASSSPPQVTSETP-------ASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVIT-------E 610
Cdd:pfam03154  447 HPPTSGLHQVPSQSPfpqhpfvPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQikeealdE 526

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039789995  611 VTRPESTIPAGRSlanitskaqeDSPLGVISTHPQMSFQSSTSQQALD 658
Cdd:pfam03154  527 AEEPESPPPPPRS----------PSPEPTVVNTPSHASQSARFYKHLD 564
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 165-513 3.69e-10

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 64.81  E-value: 3.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  165 PMKRRGAETERHMIPGNGPPlAMCHQPAPPELFETLCFPIDPASSAPPKATHRMTITSLTGRPQVTSDT-------LASS 237
Cdd:PHA03307    99 SPAREGSPTPPGPSSPDPPP-PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrqaaLPLS 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  238 SPPQG--TSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSP---------------PQVTSATSASSSPPQGTSDTPA 300
Cdd:PHA03307   178 SPEETarAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPapapgrsaaddagasSSDSSSSESSGCGWGPENECPL 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  301 SSSPPQVTSATSASSSPPQGTSDTPASSSPPqvtsatsassSPPQGTSDTPASSSPPQGTLDTPSS-----SSPPQGTSD 375
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSS----------SSPRERSPSPSPSSPGSGPAPSSPRassssSSSRESSSS 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  376 TPASSSPPqgtSETPASnSPPQGTSETPGFSSPPqvttatlvSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTP 455
Cdd:PHA03307   328 STSSSSES---SRGAAV-SPGPSPSRSPSPSRPP--------PPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVA 395

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  456 ASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPpqvtsdTPASSSPP 513
Cdd:PHA03307   396 GRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEP------WPGSPPPP 447
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 160-511 4.95e-10

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 64.40  E-value: 4.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  160 PGPLLPMKRRGAETERHMIPGNGPPLAMCHQPAPPelfetlcfPIDPASSAPPkATHRMTITSLTGRPQVTSDTLASSSP 239
Cdd:pfam03154  224 TAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPP--------SQVSPQPLPQ-PSLHGQMPPMPHSLQTGPSHMQHPVP 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  240 PQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQvtsatsasssPPQGTSDTPASSSPPQVTSATSASSSPPQ 319
Cdd:pfam03154  295 PQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQ----------SQQPPREQPLPPAPLSMPHIKPPPTTPIP 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  320 GTSDTPASSSPPQVTSATSASSSppqgTSDTPASSSPPQGTLDT--PSSSSPP------QGTSDTPASSSPP---QGTSE 388
Cdd:pfam03154  365 QLPNPQSHKHPPHLSGPSPFQMN----SNLPPPPALKPLSSLSThhPPSAHPPplqlmpQSQQLPPPPAQPPvltQSQSL 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  389 TPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPqgtsdtp 468
Cdd:pfam03154  441 PPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCP------- 513

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1039789995  469 gfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSS 511
Cdd:pfam03154  514 --LPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHAS 554
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
323-635 5.70e-10

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 63.55  E-value: 5.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  323 DTPASSSPPQVTSATSASSSppQGTSdTPASSSPPQGTLDTPSSSSPPQGTS--------DTPASSSPPQGTSETPASNS 394
Cdd:pfam03546   37 ETPAAKTPLQAKPSGKTPQV--RAAS-APAKESPRKGAPPVPPGKTGPAAAQaqagkpeeDSESSSEESDSDGETPAAAT 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  395 PPQGTSETPGFSSPPQVTTATLVSSSP------PQVTSETPASSSPTQVTSETPASSSPTQvTSDTPASNSPPQGTSDTP 468
Cdd:pfam03546  114 LTTSPAQVKPLGKNSQVRPASTVGKGPsgkganPAPPGKAGSAAPLVQVGKKEEDSESSSE-ESDSEGEAPPAATQAKPS 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  469 GFSSPTQVTT--ATLVSSSPPQVT------------------SDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQV 528
Cdd:pfam03546  193 GKILQVRPASgpAKGAAPAPPQKAgpvatqvkaerskedsesSEESSDSEEEAPAAATPAQAKPALKTPQTKASPRKGTP 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  529 TSDTSASISPPQVisDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTP---------A 599
Cdd:pfam03546  273 ITPTSAKVPPVRV--GTPAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAAAVGQAKsvgkglqgkA 350

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1039789995  600 SSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDS 635
Cdd:pfam03546  351 ASAPTKGPSGQGTAPVPPGKTGPAVAQVKAEAQEDS 386
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
203-603 6.38e-10

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 63.55  E-value: 6.38e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRMTITSLTGRPQVTSDTlaSSSPPQGTSDTPA----SSSPPQV-----TSATSASSSPPQGTSDTP 273
Cdd:pfam03546   67 PRKGAPPVPPGKTGPAAAQAQAGKPEEDSES--SSEESDSDGETPAaatlTTSPAQVkplgkNSQVRPASTVGKGPSGKG 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  274 ASSSPPQVTSATSASSSPPQGTSDTPASS--------SPPQVTSATSASSSPPQGTSDTP---ASSSPPQVTSATSASSS 342
Cdd:pfam03546  145 ANPAPPGKAGSAAPLVQVGKKEEDSESSSeesdsegeAPPAATQAKPSGKILQVRPASGPakgAAPAPPQKAGPVATQVK 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  343 PPQGTSDT-------------PASSSPPQG--TLDTPSS-SSPPQGTSDTPASSSPPQGTSETPASNSppQGTSETPGFS 406
Cdd:pfam03546  225 AERSKEDSesseessdseeeaPAAATPAQAkpALKTPQTkASPRKGTPITPTSAKVPPVRVGTPAPWK--AGTVTSPACA 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  407 SPPQVTTAT----LVSSSPPQVTSETPASSSPTQVTSET-------PASSSPTQVTSDTPASNSPPQGTSdtpgfSSPTQ 475
Cdd:pfam03546  303 SSPAVARGAqrpeEDSSSSEESESEEETAPAAAVGQAKSvgkglqgKAASAPTKGPSGQGTAPVPPGKTG-----PAVAQ 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  476 VTTATLVSSSPPQVTSD------TPASSSPPQVTSDTPASSSPPQVTSETPASSSP-------PQVTSDTSASISPPQVI 542
Cdd:pfam03546  378 VKAEAQEDSESSEEESDseeaaaTPAQVKASGKTPQAKANPAPTKASSAKGAASAPgkvvaaaAQAKQGSPAKVKPPART 457

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  543 SDTPASSSPPQ---------VTSETPASSSPTNMTSDTPASSSPTNMTSD--TPASSSPTNMTSDTPASSSP 603
Cdd:pfam03546  458 PQNSAISVRGQasvpavgkaVATAAQAQKGPVGGPQEEDSESSEEESDSEeeAPAQAKPSGKTPQVRAASAP 529
Not5 COG5665
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription];
194-618 1.01e-09

CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription];


Pssm-ID: 444384 [Multi-domain]  Cd Length: 874  Bit Score: 63.14  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  194 PELFETLCFPIDP-ASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTpassSPPQVTSATSASSSPPQGT--- 269
Cdd:COG5665    168 PVAVVVTTMIAVPsAPAAPPNAVDYSVLVPIAAQDPAASVSTPQAFNASATSGR----SQHIVQAAKRVGVEWWGDPsll 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  270 SDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPpqvTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGT-- 347
Cdd:COG5665    244 ATPPATPATEEKSSQQPKSQPTSPSGGTTPPSTNQ---LTTSNTPTSTAKAQPQPPTKKQPAKEPPSDTASGNPSAPSvl 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  348 --SDTPASSSPPqgtldTPSSSSPPQGTSDTPASSSPpqgtsetpasnsppqgtsetpgfSSPPQVTTATLVSSSPPQVT 425
Cdd:COG5665    321 inSDSPTSEDPA-----TASVPTTEETTAFTTPSSVP-----------------------STPAEKDTPATDLATPVSPT 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  426 SetPASSSPTQVTSETPASSSPTQVTSDTPASNSPP---QGTSDTPGFSSPTQvtTATLVSSSPPQVTSDTPASSSPPQv 502
Cdd:COG5665    373 P--PETSVDKKVSPDSATSSTKSEKEGGTASSPMPPniaIGAKDDVDATDPSQ--EAKEYTKNAPMTPEADSAPESSVR- 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  503 TSDTPASSSPPQVTSET---------PASSSPPQVTSDTSAS-----ISPPQVISDTPASSSPPQVTSETPASSSPTNMT 568
Cdd:COG5665    448 TEASPSAGSDLEPENTTlrdpapnaiPPPEDPSTIGRLSSGDklaneTGPPVIRRDSTPSSTADQSIVGVLAFGLDQRTQ 527

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039789995  569 SdtpASSSPTNMTSDTPASSSPTNMTSDTpaSSSPPWPvITEVTRPESTI 618
Cdd:COG5665    528 A---EISVEAASRSNPLLNSQVKSFPLGK--RSEGAKG-KTQTDRGISNA 571
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
207-591 1.85e-09

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 62.01  E-value: 1.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  207 ASSAPPKATHRMTITSLTGRPQVTSDtlasSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATS 286
Cdd:pfam03546  145 ANPAPPGKAGSAAPLVQVGKKEEDSE----SSSEESDSEGEAPPAATQAKPSGKILQVRPASGPAKGAAPAPPQKAGPVA 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  287 ASSSPPQGTSDTPASSSppqvtsatsasssPPQGTSDTPASSSPPQV---TSATSASSSPPQGTSDTPASSSPPQGTLDT 363
Cdd:pfam03546  221 TQVKAERSKEDSESSEE-------------SSDSEEEAPAAATPAQAkpaLKTPQTKASPRKGTPITPTSAKVPPVRVGT 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPP-QVTTATLVSSSPPQVTSETPASSSPTQVTSETP 442
Cdd:pfam03546  288 PAPWKAGTVTSPACASSPAVARGAQRPEEDSSSSEESESEEETAPAaAVGQAKSVGKGLQGKAASAPTKGPSGQGTAPVP 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  443 ---ASSSPTQV-TSDTPASNSPPQGTSDTPGFSSPTQVTtatlvsssPPQVTSDTPASSSPPQVTSDTPASSSP------ 512
Cdd:pfam03546  368 pgkTGPAVAQVkAEAQEDSESSEEESDSEEAAATPAQVK--------ASGKTPQAKANPAPTKASSAKGAASAPgkvvaa 439

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  513 -PQVTSETPASSSPPQVTSDTSASISPPQ---------VISDTPASSSPPQVTSETPASSSPTNMTSD--TPASSSPTNM 580
Cdd:pfam03546  440 aAQAKQGSPAKVKPPARTPQNSAISVRGQasvpavgkaVATAAQAQKGPVGGPQEEDSESSEEESDSEeeAPAQAKPSGK 519

                          410
                   ....*....|.
gi 1039789995  581 TSDTPASSSPT 591
Cdd:pfam03546  520 TPQVRAASAPA 530
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
417-595 2.44e-09

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 61.22  E-value: 2.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  417 VSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTpgfssptqvTTATLVSSSPPQVTSDTPAS 496
Cdd:pfam05539  157 LRGKDVSCCKEPKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTA---------TANQRLSSTEPVGTQGTTTS 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  497 SSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQvisDTPASSSPPQVTSETPASSSPTNMTSDTPASSS 576
Cdd:pfam05539  228 SNPEPQTEPPPSQRGPSGSPQHPPSTTSQDQSTTGDGQEHTQRR---KTPPATSNRRSPHSTATPPPTTKRQETGRPTPR 304

                          170       180
                   ....*....|....*....|.
gi 1039789995  577 PTNMT--SDTPASSSPTNMTS 595
Cdd:pfam05539  305 PTATTqsGSSPPHSSPPGVQA 325
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 364-621 3.10e-09

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 61.48  E-value: 3.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGT--SDTPASSSPPQGTSETPASNS---PPQGTSETPGFSSPpqvtTATLVSSSPPqvTSETPASssptqvT 438
Cdd:PLN03209   324 PSQRVPPKESdaADGPKPVPTKPVTPEAPSPPIeeePPQPKAVVPRPLSP----YTAYEDLKPP--TSPIPTP------P 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  439 SETPASSSPTQVTS--DTPASNSPPQGTSDTPGfSSPTQVTTATLVSSSPPQVTSDTPASSSPpqvtSDTPASSSPPQVT 516
Cdd:PLN03209   392 SSSPASSKSVDAVAkpAEPDVVPSPGSASNVPE-VEPAQVEAKKTRPLSPYARYEDLKPPTSP----SPTAPTGVSPSVS 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  517 SETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPA-SSSPTNMTS 595
Cdd:PLN03209   467 STSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSApPTALADEQH 546

                          250       260
                   ....*....|....*....|....*...
gi 1039789995  596 DTPASSSP--PWPVITEVTRPESTIPAG 621
Cdd:PLN03209   547 HAQPKPRPlsPYTMYEDLKPPTSPTPSP 574
DUF4045 pfam13254
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ...
 352-604 3.95e-09

Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.


Pssm-ID: 433066 [Multi-domain]  Cd Length: 415  Bit Score: 60.57  E-value: 3.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  352 ASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQvTSETPAS 431
Cdd:pfam13254   58 PGLSPTKLSREGSPESTSRPSSSHSEATIVRHSKDDERPSTPDEGFVKPALPRHSRSSSALSNTGSEEDSPS-LPTSPPS 136

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  432 SSPTQVT---SETPAS---------SSPTQvtSDTPASNSPP------------QGTSDTPGFSSPTQVTTATLVSSSPP 487
Cdd:pfam13254  137 PSKTMDPkrwSPTKSSwlesalnrpESPKP--KAQPSQPAQPawmkelnkirqsRASVDLGRPNSFKEVTPVGLMRSPAP 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  488 QVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTS--ASISPPQVISDTPASS-----SPPQVTSETPA 560
Cdd:pfam13254  215 GGHSKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEPppKTKELPKDSEEPAAPSksaeaSTEKKEPDTES 294

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  561 SSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPP 604
Cdd:pfam13254  295 SPETSSEKSAPSLLSPVSKASIDKPLSSPDRDPLSPKPKPQSPP 338
Hamartin pfam04388
Hamartin protein; This family includes the hamartin protein which is thought to function as a ...
 417-681 4.37e-09

Hamartin protein; This family includes the hamartin protein which is thought to function as a tumour suppressor. The hamartin protein interacts with the tuberin protein pfam03542. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder and is characterized by the presence of hamartomas in many organs, such as brain, skin, heart, lung, and kidney. It is caused by mutation either TSC1 or TSC2 tumour suppressor gene. TSC1 encodes a protein, hamartin, containing two coiled-coil regions, which have been shown to mediate binding to tuberin. The TSC2 gene codes for tuberin pfam03542. These two proteins function within the same pathway(s) regulating cell cycle, cell growth, adhesion, and vesicular trafficking.


Pssm-ID: 461287 [Multi-domain]  Cd Length: 730  Bit Score: 61.23  E-value: 4.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  417 VSSSPPqvTSETPASSSPTQVTSETP-ASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQV-TSDTP 494
Cdd:pfam04388  276 PTASPY--TDQQSSYGSSTSTPSSTPrLQLSSSSGTSPPYLSPPSIRLKTDSFPLWSPSSVCGMTTPPTSPGMVpTTPSE 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  495 ASSSPPQVTSDtpaSSSPPQVTSE-----TPASSSPPQVTSDTSASISPPQVISDTPASSSPPQvTSETPASSSP----- 564
Cdd:pfam04388  354 LSPSSSHLSSR---GSSPPEAAGEatpetTPAKDSPYLKQPPPLSDSHVHRALPASSQPSSPPR-KDGRSQSSFPplskq 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  565 --TNMTSDTPASSSPTNMTSDTpasSSPTNMTSDTpaSSSPPWPVITEVTRPESTipagRSLANITSKAQEdsplgviST 642
Cdd:pfam04388  430 apTNPNSRGLLEPPGDKSSVTL---SELPDFIKDL--ALSSEDSVEGAEEEAAIS----QELSEITTEKNE-------TD 493

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039789995  643 HPQMSFQSSTSQQALDETAGERVPTIPDFQAHSEFQKAC 681
Cdd:pfam04388  494 CSRGGLDMPFSRTMESLAGSQRSRNRIASYCSSTSQSDS 532
DUF2967 pfam11179
Protein of unknown function (DUF2967); This family of proteins with unknown function appears ...
 236-732 4.47e-09

Protein of unknown function (DUF2967); This family of proteins with unknown function appears to be restricted to Drosophila.


Pssm-ID: 402654 [Multi-domain]  Cd Length: 954  Bit Score: 61.20  E-value: 4.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  236 SSSPPQGTSDTPASSsPPQVTSATSASSSPPQGTSDTpaSSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASS 315
Cdd:pfam11179   15 SSAPPHAALAGPITA-APTGAAAAAATSTAAASAASS--TITAPGAGPGGTPTSRSRGAQAMTASLAHAAQGNANANKST 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  316 SPPQGTSDTPASSSPPQ---VTSATSASSSPPQGTSDTPASSSPPQgtldTPSSSSPPQGTSDTPASSSPPQgTSETPAS 392
Cdd:pfam11179   92 RNNSNSSNNNGKPKPLAacyMSTRSAAMMALALGQQSGEKKDKKPA----AGKAASPAQSQSQSQSQNASPH-TNNRAVS 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  393 NSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTsetpASSSPTQVTSDTPASNSPPQGTSDTPGFS- 471
Cdd:pfam11179  167 MTRPAATRRLPNAAAMSNVNAANSTCTATATSLPSNRARSKPSTPT----ATRAAAQLNGMGIFSGGSNSSGSDNDGFSa 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  472 --SPTQVTTATLVSSSPPQVTSDTPASSsppqvTSDTPASSSPPQVTSET--PASSSPPQVTSDTSASISPPQVISDTpA 547
Cdd:pfam11179  243 sgSSAATALRRLYFKSGRSIKNKINAST-----SSSTPLNGLPLNAVSNAfhNSVGGATAMHAMGTAGGVPKLVVMGT-S 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  548 SSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNmtsdtPASSSPPWPVITEVT-----RPESTIPAGR 622
Cdd:pfam11179  317 SASIPDTTINTSTDSACTLITNVTHTDTSETCDSLDLGDNSGPSE-----PLFSSLEEPLLTAIHidsehEGFGGMAGGR 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  623 SLANITSKAQ-EDSPLGVISTHPQMSFQSSTSQQ--ALDETAGERVPTIPDFQAHSEFQKACAILQRLRDFLPTSPTSAQ 699
Cdd:pfam11179  392 GGANGRGATElELTSCSRYPPRPDMNLQDSTESQesCLSILTGEPSSTTPLLSSQRRHPTGGHSPGSQRQEERRERKERE 471

                          490       500       510
                   ....*....|....*....|....*....|...
gi 1039789995  700 VSVANLLIDLSEQLLVLPFQKNNSWSSQTPAVS 732
Cdd:pfam11179  472 PSTAPPPTRGREHFTFDPPQSPKSARSSEKARS 504
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
319-632 6.68e-09

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 60.04  E-value: 6.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  319 QGTSDTPASSSPPQvtsATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGT-----SDTPASSSPPQGT-SETPAS 392
Cdd:COG5164     18 TTPAGSQGSTKPAQ---NQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQgatgpAQNQGGTTPAQNQgGTRPAG 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  393 NSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPA---SSSPTQVTsdTPASNSPPQGTSDTPG 469
Cdd:COG5164     95 NTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPgpgSTGPGGST--TPPGDGGSTTPPGPGG 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATlvsssppqvTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQvTSDTSASISPPQVISDTPASS 549
Cdd:COG5164    173 STTPPDDGGST---------TPPNKGETGTDIPTGGTPRQGPDGPVKKDDKNGKGNPP-DDRGGKTGPKDQRPKTNPIER 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  550 SPPQVTSETPASSSPTNMTSDTPASS-SPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANIT 628
Cdd:COG5164    243 RGPERPEAAALPAELTALEAENRAANpEPATKTIPETTTVKDLATVLGKKGSDLVTNLMKKGKGTNINAALDFETAATIA 322


                   ....
gi 1039789995  629 SKAQ 632
Cdd:COG5164    323 LEGN 326
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 347-677 9.73e-09

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 60.39  E-value: 9.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSPPQGTS------DTPassSPPQGTSE----TPASNSPPQGT------SETPgfSSPPQ 410
Cdd:TIGR00927   76 SSDPPKSSSEMEGEMLAPQATVGRDEATpsiameNTP---SPPRRTAKitptTPKNNYSPTAAgtervkEDTP--ATPSR 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  411 VTTATLVSSSPPQVTSETPA------SSSPTQVTSE----TPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTAT 480
Cdd:TIGR00927  151 ALNHYISTSGRQRVKSYTPKprgevkSSSPTQTREKvrkyTPSPLGRMVNSYAPSTFMTMPRSHGITPRTTVKDSEITAT 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 --LVSSSPPQ----VTSDTP----ASSSPPQVTSDTPASS-SPPQVTSETPASSSPPQVTSDTSA---------SISPPQ 540
Cdd:TIGR00927  231 ykMLETNPSKrtagKTTPTPlkgmTDNTPTFLTREVETDLlTSPRSVVEKNTLTTPRRVESNSSTnhwglvgknNLTTPQ 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  541 --VISDTPASSSPpQVTSETPASSSPTnmtsDTPASSSPTNMTSDTPASSSPTNMTsdtpaSSSPPWPVITEVTRPESTI 618
Cdd:TIGR00927  311 gtVLEHTPATSEG-QVTISIMTGSSPA----ETKASTAAWKIRNPLSRTSAPAVRI-----ASATFRGLEKNPSTAPSTP 380

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  619 PAGRSLANITSKAQE---DSPLGVISTHPQMSFQSSTSQQALDETAGERVPTIPDFQAHSEF 677
Cdd:TIGR00927  381 ATPRVRAVLTTQVHHcvvVKPAPAVPTTPSPSLTTALFPEAPSPSPSALPPGQPDLHPKAEY 442
PLAT_plant_stress cd01754
PLAT/LH2 domain of plant-specific single domain protein family with unknown function. Many of ...
 1152-1256 1.24e-08

PLAT/LH2 domain of plant-specific single domain protein family with unknown function. Many of its members are stress induced. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins.


Pssm-ID: 238852  Cd Length: 129  Bit Score: 54.85  E-value: 1.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1152 YLIQVYTGYRRRAATTAKVVITLYGSEGH-------SEPHHLCDPEKTVFERGALDVF------LLSTGSWLgdlhglRL 1218
Cdd:cd01754      3 YTIYVQTGSIWKAGTDSRISLQIYDADGPglrianlEAWGGLMGAGHDYFERGNLDRFsgrgpcLPSPPCWM------NL 76

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1039789995 1219 WHDNSGDSPSWYVSQVIVsdmtTRKKWHFQCNC-------WLAVD 1256
Cdd:cd01754     77 TSDGTGNHPGWYVNYVEV----TQAGQHAPCMQhlfaveqWLATD 117
PRK08581 PRK08581
amidase domain-containing protein;
360-596 1.54e-08

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 59.03  E-value: 1.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  360 TLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNsppqgTSETPgfssppQVTTATLVSSSPPQVTSETPASSSP-TQVT 438
Cdd:PRK08581    14 TLVLPTLTSPTAYADDPQKDSTAKTTSHDSKKSN-----DDETS------KDTSSKDTDKADNNNTSNQDNNDKKfSTID 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  439 SETPASS---SPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQvTSDTPASSSPPQVTSDTPASSSPPqv 515
Cdd:PRK08581    83 SSTSDSNniiDFIYKNLPQTNINQLLTKNKYDDNYSLTTLIQNLFNLNSDISD-YEQPRNSEKSTNDSNKNSDSSIKN-- 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  516 tSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTS 595
Cdd:PRK08581   160 -DTDTQSSKQDKADNQKAPSSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQKSSSKDNQSMSDSALDSILDQYSE 238


                   .
gi 1039789995  596 D 596
Cdd:PRK08581   239 D 239
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 442-612 2.16e-08

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 58.43  E-value: 2.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  442 PASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPpqvTSDTPASSSPPQVTSETP- 520
Cdd:pfam17823   48 PRADNKSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREG---AADGAASRALAAAASSSPs 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  521 --ASSSPPQVTSDTSASISPPQvisdTPASSSPPQVTSETP--ASSSPTNMTSDT-PASSSPTNMTSDTPASSSPTNMTS 595
Cdd:pfam17823  125 saAQSLPAAIAALPSEAFSAPR----AAACRANASAAPRAAiaAASAPHAASPAPrTAASSTTAASSTTAASSAPTTAAS 200

                          170
                   ....*....|....*..
gi 1039789995  596 DTPASSSPPWPVITEVT 612
Cdd:pfam17823  201 SAPATLTPARGISTAAT 217
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 434-634 3.62e-08

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 58.01  E-value: 3.62e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  434 PTQVTSETPASSSPTQVTSDTPASNS---PPQGTSDTPGFSSPTqvttATLVSSSPPQVTSDTPASSSPPQVTS------ 504
Cdd:PLN03209   331 KESDAADGPKPVPTKPVTPEAPSPPIeeePPQPKAVVPRPLSPY----TAYEDLKPPTSPIPTPPSSSPASSKSvdavak 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 -DTPASSSPPQVTSETPASSsPPQVTSDTSASISPPQVISD--TPASSSP-PQVTSETPASSSPT-NMTSDTPASSSPTN 579
Cdd:PLN03209   407 pAEPDVVPSPGSASNVPEVE-PAQVEAKKTRPLSPYARYEDlkPPTSPSPtAPTGVSPSVSSTSSvPAVPDTAPATAATD 485

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  580 MTSDTPASSSPTNMTS-----DTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQED 634
Cdd:PLN03209   486 AAAPPPANMRPLSPYAvyddlKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQ 545
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
294-487 4.07e-08

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 57.84  E-value: 4.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  294 GTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGT 373
Cdd:COG3469     20 VTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVAT 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  374 SDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSD 453
Cdd:COG3469    100 STASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTP 179

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1039789995  454 TPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPP 487
Cdd:COG3469    180 SATTTATATTASGATTPSATTTATTTGPPTPGLP 213
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
345-514 4.60e-08

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 56.98  E-value: 4.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPASSSPPQGTLDTPSSSSPPQG----TSDTPASSSPPQGTSETPASNSPPQGTseTPGFSSPPQVTTATLVSSS 420
Cdd:pfam05539  176 KTTSWPTEVSHPTYPSQVTPQSQPATQGhqtaTANQRLSSTEPVGTQGTTTSSNPEPQT--EPPPSQRGPSGSPQHPPST 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  421 PPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPP 500
Cdd:pfam05539  254 TSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTTKRQET-----GRPTPRPTATTQSGSSPPHSSPPGVQANPT 328

                          170
                   ....*....|....
gi 1039789995  501 QVTSDTPASSSPPQ 514
Cdd:pfam05539  329 TQNLVDCKELDPPK 342
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
364-577 5.06e-08

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 56.98  E-value: 5.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETpgfssppqvTTATLVSSSPPQVTSETPASSSPTQVTSETPA 443
Cdd:pfam05539  169 KTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTA---------TANQRLSSTEPVGTQGTTTSSNPEPQTEPPPS 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  444 SSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVT-------TATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQvT 516
Cdd:pfam05539  240 QRGPSGSPQHPPSTTSQDQSTTGDGQEHTQRRKTppatsnrRSPHSTATPPPTTKRQETGRPTPRPTATTQSGSSPPH-S 318

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  517 SETPASSSPPQVTSDTSASISPPQVIS-----DTPASSSPPQVTSETPASSSPTNMTSDTPASSSP 577
Cdd:pfam05539  319 SPPGVQANPTTQNLVDCKELDPPKPNSicygvGIYNEALPRGCDIVVPLCSTYTIMCMDTYYSKPF 384
PHA03255 PHA03255
BDLF3; Provisional
 438-608 9.87e-08

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 54.52  E-value: 9.87e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  438 TSETPASSSPTQVTSDTPAsnsppqgTSDTPGFSSPTQVTTATLVSSSPPqVTSDTPASSSPPQVTSdTPASSSPPQVTS 517
Cdd:PHA03255    25 TSSGSSTASAGNVTGTTAV-------TTPSPSASGPSTNQSTTLTTTSAP-ITTTAILSTNTTTVTS-TGTTVTPVPTTS 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  518 ETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDT 597
Cdd:PHA03255    96 NASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELPTVPDERQ 175

                          170
                   ....*....|...
gi 1039789995  598 PASSS--PPWPVI 608
Cdd:PHA03255   176 PSLSYglPLWTLV 188
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
382-577 1.91e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 56.01  E-value: 1.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  382 PPQGTSETPASNSPPQGTSETPGfsSPPQVTTATLVSSSPPQvtseTPASSSPTQVTSETPASSSPTQVTSDTPASNSPP 461
Cdd:PRK07003   360 PAVTGGGAPGGGVPARVAGAVPA--PGARAAAAVGASAVPAV----TAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPP 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  462 Q-GTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSE-TPASSSPPQVTSDTSASISPP 539
Cdd:PRK07003   434 AtADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEpAPRAAAPSAATPAAVPDARAP 513

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1039789995  540 QVIS--DTPASSSPPqvtseTPASSSPTnmtsdtPASSSP 577
Cdd:PRK07003   514 AAASreDAPAAAAPP-----APEARPPT------PAAAAP 542
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 245-644 1.98e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 55.89  E-value: 1.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  245 DTPASSSPPQVTSATSA------SSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPP 318
Cdd:PRK14949   369 DDPAEISLPEGQTPSALaaavqaPHANEPQFVNAAPAEKKTALTEQTTAQQQVQAANAEAVAEADASAEPADTVEQALDD 448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  319 QgTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPA---SSSPPQGTSETPASNSP 395
Cdd:PRK14949   449 E-SELLAALNAEQAVILSQAQSQGFEASSSLDADNSAVPEQIDSTAEQSVVNPSVTDTQVddtSASNNSAADNTVDDNYS 527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  396 PQGTSETPG--------------------------FSSPPQVTTATLVSSSPPQVTSET-PASSSPTQVTSETPASSSP- 447
Cdd:PRK14949   528 AEDTLESNGldegdyaqdsapldayqddyvafsseSYNALSDDEQHSANVQSAQSAAEAqPSSQSLSPISAVTTAAASLa 607

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  448 ----------------TQVTSDTPASNSPPQGTSDTPGFSSPtqvttatlvsSSPPQVTSDTPASSSPPQVTSdtpASSS 511
Cdd:PRK14949   608 dddildavlaardsllSDLDALSPKEGDGKKSSADRKPKTPP----------SRAPPASLSKPASSPDASQTS---ASFD 674

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  512 PPQVTSETPASSSPPQVTSDTSASISPPQV-ISDTPASSSPPQVtseTPASSSPTNMTSDTPASSSPTNMTSDTPASSSP 590
Cdd:PRK14949   675 LDPDFELATHQSVPEAALASGSAPAPPPVPdPYDRPPWEEAPEV---ASANDGPNNAAEGNLSESVEDASNSELQAVEQQ 751

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039789995  591 TNMTSDTPASSSPPwpviTEVTRPESTIPAGRSLANITSKaqedSPLGVISTHP 644
Cdd:PRK14949   752 ATHQPQVQAEAQSP----ASTTALTQTSSEVQDTELNLVL----LSSGSITGHP 797
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
209-603 2.07e-07

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 55.46  E-value: 2.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  209 SAPPKATHRMTITSLTGRPQVTSDtlaSSSPPQGTSD--TPASSSPPQVTSATSASSSPPQGTS--DTPASSSPPQVTSA 284
Cdd:pfam03546    2 PATPGKAGPAATQAKAGKPEEDSE---SSSEEESDSEeeTPAAKTPLQAKPSGKTPQVRAASAPakESPRKGAPPVPPGK 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  285 TSASSSPPQ-GTSDTPASSSPPQVTSATSASSSPPQGTSdtPASSSP----PQVTSATSASS-SPPQGTSDTPASSSPPQ 358
Cdd:pfam03546   79 TGPAAAQAQaGKPEEDSESSSEESDSDGETPAAATLTTS--PAQVKPlgknSQVRPASTVGKgPSGKGANPAPPGKAGSA 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  359 GTL--------DTPSSSSPPQGTSDTPASSS---PPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSE 427
Cdd:pfam03546  157 APLvqvgkkeeDSESSSEESDSEGEAPPAATqakPSGKILQVRPASGPAKGAAPAPPQKAGPVATQVKAERSKEDSESSE 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPTQVTSDTPAsnSPPQGTSDTPgfsSPTQVTTATLVSSSPPQV-TSDTPASSSPPQVTSDT 506
Cdd:pfam03546  237 ESSDSEEEAPAAATPAQAKPALKTPQTKA--SPRKGTPITP---TSAKVPPVRVGTPAPWKAgTVTSPACASSPAVARGA 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  507 --PASSSPPQVTSETPASSSPP----QVTS-----DTSASISPPQVISDTPASSSPP--------QVTSETPASSSPTNM 567
Cdd:pfam03546  312 qrPEEDSSSSEESESEEETAPAaavgQAKSvgkglQGKAASAPTKGPSGQGTAPVPPgktgpavaQVKAEAQEDSESSEE 391

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1039789995  568 TSD------TPASSSPTNMTSDTPASSSPTNMTSDTPASSSP 603
Cdd:pfam03546  392 ESDseeaaaTPAQVKASGKTPQAKANPAPTKASSAKGAASAP 433
PHA03378 PHA03378
EBNA-3B; Provisional
 183-624 2.38e-07

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 55.46  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  183 PPLAMCHQPAPPELFETLCFPID-PASSAPPKAThrmtITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSA 261
Cdd:PHA03378   529 PPQPRAGRRAPCVYTEDLDIESDePASTEPVHDQ----LLPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQ 604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  262 SSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDT-------PASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVT 334
Cdd:PHA03378   605 TPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPItfnvlvfPTPHQPPQVEITPYKPTWTQIGHIPYQPSPTGANTM 684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  335 SATSASSSPPQGTSDTPASSSPPQGtldTPSSSSPPQGtsdTPASSSPPQGtseTPASNSPPQGtseTPGFSSPPQvttA 414
Cdd:PHA03378   685 LPIQWAPGTMQPPPRAPTPMRPPAA---PPGRAQRPAA---ATGRARPPAA---APGRARPPAA---APGRARPPA---A 749

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  415 TLVSSSPPQvtsetpASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGtsdTPGFSSPTQVTTATLVSSSPPQVTSDTP 494
Cdd:PHA03378   750 APGRARPPA------AAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRG---APTPQPPPQAGPTSMQLMPRAAPGQQGP 820

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  495 ASSSPPQ-----VTSDTPASSSPPQVTSETPASSSP-PQvtSDTSASISPPQVIsdTPASSSPPQVtsetpasssPTNMT 568
Cdd:PHA03378   821 TKQILRQlltggVKRGRPSLKKPAALERQAAAGPTPsPG--SGTSDKIVQAPVF--YPPVLQPIQV---------MRQLG 887

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  569 SDTPASSSptnmtsdtPASSSPTNMTSDTPASSSPPWPVITEVTR------PESTIPAGRSL 624
Cdd:PHA03378   888 SVRAAAAS--------TVTQAPTEYTGERRGVGPMHPTDIPPSKRaktdayVESQPPHGGQS 941
PRK08581 PRK08581
amidase domain-containing protein;
402-705 2.53e-07

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 55.18  E-value: 2.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  402 TPGFSSPpQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSsptqvTSDTPASNSPPQGTSDTPgFSSPTQVTTAT- 480
Cdd:PRK08581    17 LPTLTSP-TAYADDPQKDSTAKTTSHDSKKSNDDETSKDTSSKD-----TDKADNNNTSNQDNNDKK-FSTIDSSTSDSn 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 ---------LVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTS-ETPASSS-PPQVTSDTSAS-ISPPQvisdTPAS 548
Cdd:PRK08581    90 niidfiyknLPQTNINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDyEQPRNSEkSTNDSNKNSDSsIKNDT----DTQS 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  549 SSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSppwpvitevtrpESTIPAGRSLANIT 628
Cdd:PRK08581   166 SKQDKADNQKAPSSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQKSSSK------------DNQSMSDSALDSIL 233

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  629 SKAQEDSPLgvisTHPQMSFQSSTSQQaldETAGERVPTIPdfqAHSEFQKACAILQRLRDFLPTSPTSAQVSVANL 705
Cdd:PRK08581   234 DQYSEDAKK----TQKDYASQSKKDKT---ETSNTKNPQLP---TQDELKHKSKPAQSFENDVNQSNTRSTSLFETG 300
rne PRK10811
ribonuclease E; Reviewed
 409-615 2.78e-07

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 55.43  E-value: 2.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  409 PQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDT----PASNSPPQGTSDTPGFSSPTQVTTATLVSs 484
Cdd:PRK10811   848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEvveePVVVAEPQPEEVVVVETTHPEVIAAPVTE- 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  485 sPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPP-QVISDTPASSSPPQVTSETPASSS 563
Cdd:PRK10811   927 -QPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAaPVVAEVAAEVETVTAVEPEVAPAQ 1005

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  564 PTNMTSDTPASSSPtnMTSdTPAsssptnmtsdtPASSSPPwPVITEVTRPE 615
Cdd:PRK10811  1006 VPEATVEHNHATAP--MTR-APA-----------PEYVPEA-PRHSDWQRPT 1042
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 203-512 2.79e-07

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 55.31  E-value: 2.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRmTITSLTGRPQVTSDTLASSSP--------PQGTSDTPASSSP-PQVTSATSASSSPPQG-TSDT 272
Cdd:pfam05109  509 PTSAVTTPTPNATSP-TPAVTTPTPNATSPTLGKTSPtsavttptPNATSPTPAVTTPtPNATIPTLGKTSPTSAvTTPT 587

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  273 PASSSPP--QVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPqvtSATSASSSPPqgTSDT 350
Cdd:pfam05109  588 PNATSPTvgETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRP---SSISETLSPS--TSDN 662

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPpqgTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPA 430
Cdd:pfam05109  663 STSHMP---LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQ 739

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  431 SSSpTQVTSETPASSSPTQVTSDTPASNSPPQG--TSDTP----GFSSPTQVTTATLVSSSPPQVTSDTPAS---SSPP- 500
Cdd:pfam05109  740 APS-GQKTAVPTVTSTGGKANSTTGGKHTTGHGarTSTEPttdyGGDSTTPRTRYNATTYLPPSTSSKLRPRwtfTSPPv 818

                          330
                   ....*....|....*
gi 1039789995  501 ---QVTSDTPASSSP 512
Cdd:pfam05109  819 ttaQATVPVPPTSQP 833
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
414-666 2.88e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 55.27  E-value: 2.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  414 ATLVSSSPPQVTSETPASSSPTQVTsetPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDT 493
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAA---PAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAP 448

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  494 PASSSPPQVtsdtPASSSPPQVTS-ETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTP 572
Cdd:PRK12323   449 APAPAPAAA----PAAAARPAAAGpRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAE 524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  573 ASSSPTNMTSDTPASSSptnmtsdTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVISTHP------QM 646
Cdd:PRK12323   525 SIPDPATADPDDAFETL-------APAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARLPvrglaqQL 597

                          250       260
                   ....*....|....*....|
gi 1039789995  647 SFQSSTsQQALDETAGERVP 666
Cdd:PRK12323   598 ARQSEL-AGVEGDTVRLRVP 616
CLECT cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type ...
 37-142 3.21e-07

C-type lectin (CTL)/C-type lectin-like (CTLD) domain; CLECT: C-type lectin (CTL)/C-type lectin-like (CTLD) domain; protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins. This group is chiefly comprised of eukaryotic CTLDs, but contains some, as yet functionally uncharacterized, bacterial CTLDs. Many CTLDs are calcium-dependent carbohydrate binding modules; other CTLDs bind protein ligands, lipids, and inorganic surfaces, including CaCO3 and ice. Animal C-type lectins are involved in such functions as extracellular matrix organization, endocytosis, complement activation, pathogen recognition, and cell-cell interactions. For example: mannose-binding lectin and lung surfactant proteins A and D bind carbohydrates on surfaces (e.g. pathogens, allergens, necrotic, and apoptotic cells) and mediate functions associated with killing and phagocytosis; P (platlet)-, E (endothelial)-, and L (leukocyte)- selectins (sels) mediate the initial attachment, tethering, and rolling of lymphocytes on inflamed vascular walls enabling subsequent lymphocyte adhesion and transmigration. CTLDs may bind a variety of carbohydrate ligands including mannose, N-acetylglucosamine, galactose, N-acetylgalactosamine, and fucose. Several CTLDs bind to protein ligands, and only some of these binding interactions are Ca2+-dependent; including the CTLDs of Coagulation Factors IX/X (IX/X) and Von Willebrand Factor (VWF) binding proteins, and natural killer cell receptors. C-type lectins, such as lithostathine, and some type II antifreeze glycoproteins function in a Ca2+-independent manner to bind inorganic surfaces. Many proteins in this group contain a single CTLD; these CTLDs associate with each other through several different surfaces to form dimers, trimers, or tetramers, from which ligand-binding sites project in different orientations. Various vertebrate type 1 transmembrane proteins including macrophage mannose receptor, endo180, phospholipase A2 receptor, and dendritic and epithelial cell receptor (DEC205) have extracellular domains containing 8 or more CTLDs; these CTLDs remain in the parent model. In some members (IX/X and VWF binding proteins), a loop extends to the adjoining domain to form a loop-swapped dimer. A similar conformation is seen in the macrophage mannose receptor CRD4's putative non-sugar bound form of the domain in the acid environment of the endosome. Lineage specific expansions of CTLDs have occurred in several animal lineages including Drosophila melanogaster and Caenorhabditis elegans; these CTLDs also remain in the parent model.


Pssm-ID: 153057 [Multi-domain]  Cd Length: 116  Bit Score: 50.31  E-value: 3.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995   37 SCYQLNRLFCDFQEADNYCHAQRGRLAHTWNPKLRGFLKSFL---NEETVW-------------WVRGNLTLPGSHPGIN 100
Cdd:cd00037      1 SCYKFSTEKLTWEEAQEYCRSLGGHLASIHSEEENDFLASLLkksSSSDVWiglndlssegtwkWSDGSPLVDYTNWAPG 80

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  101 QTGGDDvlrnqkPGECpsvVTHSNAVFSRWN--LCIEKHHFICQ 142
Cdd:cd00037     81 EPNPGG------SEDC---VVLSSSSDGKWNdvSCSSKLPFICE 115
PRK10905 PRK10905
cell division protein DamX; Validated
 377-593 3.54e-07

cell division protein DamX; Validated


Pssm-ID: 236792 [Multi-domain]  Cd Length: 328  Bit Score: 53.79  E-value: 3.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  377 PASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQV-TSETPASSSPTQVTSDTP 455
Cdd:PRK10905    23 PSTSSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAEQTAGNTQQDVSLPPISSTPTQGqTPVATDGQQRVEVQGDLN 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  456 ASNSPPQGTSDTPGFSS----PTQVTT-----------ATLVSSSPPQVTSDTPA------SSSPPQVTSDTPASSSPPQ 514
Cdd:PRK10905   103 NALTQPQNQQQLNNVAVnstlPTEPATvapvrngnasrQTAKTQTAERPATTRPArkqaviEPKKPQATAKTEPKPVAQT 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  515 VTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPT--NMTSDTPASSSptNMTSDTPASSSPTN 592
Cdd:PRK10905   183 PKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGGKTagNVGSLKSAPSS--HYTLQLSSSSNYDN 260


                   .
gi 1039789995  593 M 593
Cdd:PRK10905   261 L 261
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
384-608 6.26e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 54.11  E-value: 6.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  384 QGTSETPASNSPPQGTSETPGFSSPPQVTTAtlvSSSPPQVTSETPASSSPTQVTSETPASSSPTQVtSDTPASNSPPQG 463
Cdd:PRK12323   368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPA---PAAPPAAPAAAPAAAAAARAVAAAPARRSPAPE-ALAAARQASARG 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  464 tsdTPGFSSPTQVTTATLVSSSPPQVTS-DTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVI 542
Cdd:PRK12323   444 ---PGGAPAPAPAPAAAPAAAARPAAAGpRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAG 520

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  543 SDTpASSSPPQVTSETPASSSPTNMTSDTPAsSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVI 608
Cdd:PRK12323   521 WVA-ESIPDPATADPDDAFETLAPAPAAAPA-PRAAAATEPVVAPRPPRASASGLPDMFDGDWPAL 584
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 352-578 6.53e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 53.94  E-value: 6.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  352 ASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETpgfSSPPQVTTATLVSSSPPQVTSETPAS 431
Cdd:PRK08691   363 AASCDANAVIENTELQSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAA---AMPSEGKTAGPVSNQENNDVPPWEDA 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  432 SSPTQvTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDtpasSSPPQVTSDTPASSS 511
Cdd:PRK08691   440 PDEAQ-TAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSENPIQATPN----DEAVETETFAHEAPA 514

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  512 PPQVTSETPASSSPPQvtsdTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPT 578
Cdd:PRK08691   515 EPFYGYGFPDNDCPPE----DGAEIPPPDWEHAAPADTAGGGADEEAEAGGIGGNNTPSAPPPEFST 577
GPS pfam01825
GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for ...
 1041-1079 7.63e-07

GPCR proteolysis site, GPS, motif; The GPS motif is found in GPCRs, and is the site for auto-proteolysis, so is thus named, GPS. The GPS motif is a conserved sequence of ~40 amino acids containing canonical cysteine and tryptophan residues, and is the most highly conserved part of the domain. In most, if not all, cell-adhesion GPCRs these undergo autoproteolysis in the GPS between a conserved aliphatic residue (usually a leucine) and a threonine, serine, or cysteine residue. In higher eukaryotes this motif is found embedded in the C-terminal beta-stranded part of a GAIN domain - GPCR-Autoproteolysis INducing (GAIN). The GAIN-GPS domain adopts a fold in which the GPS motif, at the C-terminus, forms five beta-strands that are tightly integrated into the overall GAIN domain. The GPS motif, evolutionarily conserved from tetrahymena to mammals, is the only extracellular domain shared by all human cell-adhesion GPCRs and PKD proteins, and is the locus of multiple human disease mutations. The GAIN-GPS domain is both necessary and sufficient functionally for autoproteolysis, suggesting an autoproteolytic mechanism whereby the overall GAIN domain fine-tunes the chemical environment in the GPS to catalyze peptide bond hydrolysis. In the cell-adhesion GPCRs and PKD proteins, the GPS motif is always located at the end of their long N-terminal extracellular regions, immediately before the first transmembrane helix of the respective protein.


Pssm-ID: 460350  Cd Length: 44  Bit Score: 46.92  E-value: 7.63e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1039789995 1041 QCYFWDRYNRT---WKSDGCQVGPKSTiLKTQCLCDHLTFFS 1079
Cdd:pfam01825    2 QCVFWDFTNSTtgrWSTEGCTTVSLND-THTVCSCNHLTSFA 42
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 349-669 1.35e-06

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 53.15  E-value: 1.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  349 DTPASSSPPQGtldTPSSSSPPQGTSDTPASSSPPQGTSEtpaSNSPPQGTSetPGFSSPPQVTtatlvssSPPQVTSET 428
Cdd:PTZ00449   503 DSDKHDEPPEG---PEASGLPPKAPGDKEGEEGEHEDSKE---SDEPKEGGK--PGETKEGEVG-------KKPGPAKEH 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQ--VTSDT 506
Cdd:PTZ00449   568 KPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQrpSSPER 647

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  507 PASSSPPQvTSETPASSSPP-------QVTSDTS-ASISPPQVISDTPASSSPPQVTSETPASSSPTNMTsdTPASSSPT 578
Cdd:PTZ00449   648 PEGPKIIK-SPKPPKSPKPPfdpkfkeKFYDDYLdAAAKSKETKTTVVLDESFESILKETLPETPGTPFT--TPRPLPPK 724

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  579 NMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTiPAGRSLANITSKAQEDSPLGVISTHPQMSFQSSTSQQALD 658
Cdd:PTZ00449   725 LPRDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHET-PADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDSPSEHE 803

                          330
                   ....*....|.
gi 1039789995  659 ETAGERVPTIP 669
Cdd:PTZ00449   804 DKPPGDHPSLP 814
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 240-589 1.53e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 52.99  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  240 PQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQ 319
Cdd:NF033609   558 PEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  320 GTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGT 399
Cdd:NF033609   638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 717

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  400 SETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPA-SNSPPQGTSDTPGFSSPTQVTT 478
Cdd:NF033609   718 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSD 797

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSET 558
Cdd:NF033609   798 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNS 877

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1039789995  559 PASSSPTNMTSDTPASSSPTNMT-SDTPASSS 589
Cdd:NF033609   878 PKNGTNASNKNEAKDSKEPLPDTgSEDEANTS 909
PHA03255 PHA03255
BDLF3; Provisional
 464-622 1.57e-06

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 51.06  E-value: 1.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  464 TSDTPGFSSPTQVTTATlvsssppQVTSDTPASSSPPQVTSDTPASSSPPqVTSETPASSSPPQVTSdTSASISPPQVIS 543
Cdd:PHA03255    25 TSSGSSTASAGNVTGTT-------AVTTPSPSASGPSTNQSTTLTTTSAP-ITTTAILSTNTTTVTS-TGTTVTPVPTTS 95

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  544 DTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGR 622
Cdd:PHA03255    96 NASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELPTVPDER 174
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 423-582 1.88e-06

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 52.40  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  423 QVTSETPASSSPTQVTSETPASSSPTQVTSDTPASN------SPPQGTSDTPG-FSSPTQVTTATLVSSSPPQVTSDTPA 495
Cdd:PLN02217   508 EVQNTGPGAAITKRVTWPGIKKLSDEEILKFTPAQYiqgdawIPGKGVPYIPGlFAGNPGSTNSTPTGSAASSNTTFSSD 587

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  496 SSSppqvTSDTPASSSPPQVTSETPASSSpPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNM-TSDTPAS 574
Cdd:PLN02217   588 SPS----TVVAPSTSPPAGHLGSPPATPS-KIVSPSTSPPASHLGSPSTTPSSPESSIKVASTETASPESSIkVASTESS 662


                   ....*...
gi 1039789995  575 SSPTNMTS 582
Cdd:PLN02217   663 VSMVSMST 670
PHA03255 PHA03255
BDLF3; Provisional
 425-588 2.64e-06

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 50.29  E-value: 2.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSETPASSSPTQVTSETpASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTS-DTPASSSPPQVT 503
Cdd:PHA03255    25 TSSGSSTASAGNVTGTT-AVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPvPTTSNASTINVT 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  504 SDTPASSSppqVTSETPASSSPPQVTSDTSasisppQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSD 583
Cdd:PHA03255   104 TKVTAQNI---TATEAGTGTSTGVTSNVTT------RSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELPTVPDER 174


                   ....*
gi 1039789995  584 TPASS 588
Cdd:PHA03255   175 QPSLS 179
motB PRK12799
flagellar motor protein MotB; Reviewed
 347-465 2.72e-06

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 51.64  E-value: 2.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTldTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVS--SSPPQV 424
Cdd:PRK12799   296 HGTVPVAAVTPSSA--VTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVAlpAAEPVN 373

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  425 TSETPASSSPTQVTSE---TPASSSPTQVTSDTPASNSPPQGTS 465
Cdd:PRK12799   374 MQPQPMSTTETQQSSTgniTSTANGPTTSLPAAPASNIPVSPTS 417
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 377-670 3.12e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.91  E-value: 3.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  377 PASSSPPQGTS---ETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPtQVTSETPASSSPTQVTSD 453
Cdd:PRK07764   365 PSASDDERGLLarlERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAP-AAAPQPAPAPAPAPAPPS 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  454 TPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQ------------------- 514
Cdd:PRK07764   444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAgaddaatlrerwpeilaav 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  515 ---VTSETPASSSPPQVTS----------DTSAS---ISPPQ---------------------VISDTPASSSPPQVTSE 557
Cdd:PRK07764   524 pkrSRKTWAILLPEATVLGvrgdtlvlgfSTGGLarrFASPGnaevlvtalaeelggdwqveaVVGPAPGAAGGEGPPAP 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  558 TPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPL 637
Cdd:PRK07764   604 ASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPP 683

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1039789995  638 GVISTHPQMSFQSSTSQQALDETAGERVPTIPD 670
Cdd:PRK07764   684 APAPAAPAAPAGAAPAQPAPAPAATPPAGQADD 716
motB PRK12799
flagellar motor protein MotB; Reviewed
 477-607 3.81e-06

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 51.25  E-value: 3.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  477 TTATLVSSSPPqvTSDTPASSSPPQVTSDTPASSSPPqvtseTPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTS 556
Cdd:PRK12799   296 HGTVPVAAVTP--SSAVTQSSAITPSSAAIPSPAVIP-----SSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPA 368

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  557 ETPASSSPTNMTSDTPASSSPTNMtsdTPASSSPTNMTSDTPASSSPPWPV 607
Cdd:PRK12799   369 AEPVNMQPQPMSTTETQQSSTGNI---TSTANGPTTSLPAAPASNIPVSPT 416
PHA03255 PHA03255
BDLF3; Provisional
 413-575 4.03e-06

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 49.90  E-value: 4.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  413 TATLVSSSPPQVTSETPASSSpTQVTSETPASSSPTQVTSDTPASNSPPQGTsdTPGFSSPTQVTTATLVSSSPPQVTSD 492
Cdd:PHA03255    20 TSLIWTSSGSSTASAGNVTGT-TAVTTPSPSASGPSTNQSTTLTTTSAPITT--TAILSTNTTTVTSTGTTVTPVPTTSN 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  493 TPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTP 572
Cdd:PHA03255    97 ASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELPTVPDERQP 176


                   ...
gi 1039789995  573 ASS 575
Cdd:PHA03255   177 SLS 179
PHA03247 PHA03247
large tegument protein UL36; Provisional
 352-606 4.53e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 4.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  352 ASSSPPQGTLDTPSSssPPQGTSDTPASSSPPQGTSETPAsnsPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPAS 431
Cdd:PHA03247   243 VISHPLRGDIAAPAP--PPVVGEGADRAPETARGATGPPP---PPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPP 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  432 SSPTQVTSETPASSSPTQVTSDTPASNSP-PQGTSDT--PGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSD--- 505
Cdd:PHA03247   318 PAPAGDAEEEDDEDGAMEVVSPLPRPRQHyPLGFPKRrrPTWTPPSSLEDLSAGRHHPKRASLPTRKRRSARHAATPfar 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  506 TPASSSPPQVTSETPASSSPPqvtsdtsasiSPPQVISDTPASSSPPQVTSETPASSSPTNmtsdTPASSSPTNMTSDT- 584
Cdd:PHA03247   398 GPGGDDQTRPAAPVPASVPTP----------APTPVPASAPPPPATPLPSAEPGSDDGPAP----PPERQPPAPATEPAp 463

                          250       260
                   ....*....|....*....|..
gi 1039789995  585 PASSSPTNMTSDTPASSSPPWP 606
Cdd:PHA03247   464 DDPDDATRKALDALRERRPPEP 485
PRK10856 PRK10856
cytoskeleton protein RodZ;
496-577 5.79e-06

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 50.02  E-value: 5.79e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  496 SSSPPQVTSDTPASSSPPQVTSETPASSSP--PQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPA 573
Cdd:PRK10856   168 TTTDPATTPAPAAPVDTTPTNSQTPAVATApaPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVSTP 247


                   ....
gi 1039789995  574 SSSP 577
Cdd:PRK10856   248 AADP 251
PAP1 pfam08601
Transcription factor PAP1; The transcription factor Pap1 regulates antioxidant-gene ...
 346-536 8.09e-06

Transcription factor PAP1; The transcription factor Pap1 regulates antioxidant-gene transcription in response to H2O2. This region is cysteine rich. Alkylation of cysteine residues following treatment with a cysteine alkylating agent can mask the accessibility of the nuclear exporter Crm1, triggering nuclear accumulation and Pap1 dependent transcriptional expression.


Pssm-ID: 369990  Cd Length: 363  Bit Score: 49.86  E-value: 8.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  346 GTSDTPASSSPPQGTLDTPSSSSPPqgtSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVT 425
Cdd:pfam08601   31 QLSKAKQNTAKPGVRSDSRSPSPNA---STSTPDSQPPPSASSSTTPNQGSNGLNAFTGEDNNNYSNSAANPGATRGSTA 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  426 SETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQ--VTTATLVSSSPPQVTSDTPASSSPPQVT 503
Cdd:pfam08601  108 SSARSQSSPYSFGSGTSTSSDSPSSSSSSHQGQLSSCGTSPEPSTQSPGGqkSVETMIGEEQCAHGTIDGEKSFCAKLGM 187

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1039789995  504 SDTPASSSPPQVTSETPASSSPPQVTSDTSASI 536
Cdd:pfam08601  188 ACGNINNPIPAAMSKSNSLSNTPGHASNDSNGL 220
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 270-603 8.17e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 50.68  E-value: 8.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  270 SDT-PASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTS 348
Cdd:NF033609   561 SDSdPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 640

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  349 DTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSET 428
Cdd:NF033609   641 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 720

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PA-SSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTP 507
Cdd:NF033609   721 DSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 800

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  508 ASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPAS 587
Cdd:NF033609   801 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSPKN 880

                          330
                   ....*....|....*.
gi 1039789995  588 SSPTNMTSDTPASSSP 603
Cdd:NF033609   881 GTNASNKNEAKDSKEP 896
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
473-638 8.82e-06

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 50.05  E-value: 8.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  473 PTQVTTAtlvsssppQVTSDTPASSSPPQVTSDTPASSSPPQ----VTSETPASSSPPQVTSDTSASISPPQVISDTPAS 548
Cdd:pfam05539  169 KTAVTTS--------KTTSWPTEVSHPTYPSQVTPQSQPATQghqtATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQ 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  549 SSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSdTPASSSPPWPVITEVTRPESTIPAGRSLANIT 628
Cdd:pfam05539  241 RGPSGSPQHPPSTTSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTA-TPPPTTKRQETGRPTPRPTATTQSGSSPPHSS 319

                          170
                   ....*....|
gi 1039789995  629 SKAQEDSPLG 638
Cdd:pfam05539  320 PPGVQANPTT 329
PHA03377 PHA03377
EBNA-3C; Provisional
 203-657 9.51e-06

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 50.44  E-value: 9.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQ---VTSATSASSSPPQGTSDTPASSSPP 279
Cdd:PHA03377   450 PERPGPSDQPSVPVEPAHLTPVEHTTVILHQPPQSPPTVAIKPAPPPSRRRRgacVVYDDDIIEVIDVETTEEEESVTQP 529

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  280 QVTSATSASSSPPQGTSD--------TPASSSPPQVTSATSASSSPPQGTSDTPASSspPQVTSATSASSSPPQGTSDTP 351
Cdd:PHA03377   530 AKPHRKVQDGFQRSGRRQkratppkvSPSDRGPPKASPPVMAPPSTGPRVMATPSTG--PRDMAPPSTGPRQQAKCKDGP 607

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  352 ASSSPPQgtlDTPSSSSP-----------------PQGTSDTPAS------SSPPQGTSETPASNSPPQGTSETPGFSSP 408
Cdd:PHA03377   608 PASGPHE---KQPPSSAPrdmapsvvrmflrerllEQSTGPKPKSfwemraGRDGSGIQQEPSSRRQPATQSTPPRPSWL 684

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  409 PQVTTATLVSSSPPQVTSETPASS-SPTQVTS--ETPASSSPTQVT--SDTPASNSPPQGTSDTPGFSSP--TQVTTATL 481
Cdd:PHA03377   685 PSVFVLPSVDAGRAQPSEESHLSSmSPTQPISheEQPRYEDPDDPLdlSLHPDQAPPPSHQAPYSGHEEPqaQQAPYPGY 764

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  482 VSSSPPQV--------------TSDTPASSSPPQVTSDTPASSSPPQVTSETPAsSSPPQVTSDTSASISPPQviSDTPA 547
Cdd:PHA03377   765 WEPRPPQApylgyqepqaqgvqVSSYPGYAGPWGLRAQHPRYRHSWAYWSQYPG-HGHPQGPWAPRPPHLPPQ--WDGSA 841

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  548 SSSPPQVTSETPASSSPTNMTSDTpaSSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPvitevTR-PESTIPAGRSLAn 626
Cdd:PHA03377   842 GHGQDQVSQFPHLQSETGPPRLQL--SQVPQLPYSQTLVSSSAPSWSSPQPRAPIRPIP-----TRfPPPPMPLQDSMA- 913

                          490       500       510
                   ....*....|....*....|....*....|.
gi 1039789995  627 itskAQEDSPLgviSTHPQMSFQSSTSQQAL 657
Cdd:PHA03377   914 ----VGCDSSG---TACPSMPFASDYSQGAF 937
PRK13914 PRK13914
invasion associated endopeptidase;
417-602 9.78e-06

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 49.80  E-value: 9.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  417 VSSSPPQVTSETPASSSPTQVTsetPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATL--------------- 481
Cdd:PRK13914   143 VTSTPVAPTQEVKKETTTQQAA---PAAETKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVksgdtiwalsvkygv 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  482 ----------VSSSPPQVTSD----TPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPA 547
Cdd:PRK13914   220 svqdimswnnLSSSSIYVGQKlaikQTANTATPKAEVKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKAPT 299

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  548 SSS----PPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSS 602
Cdd:PRK13914   300 EAAkpapAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSS 358
GPS smart00303
G-protein-coupled receptor proteolytic site domain; Present in latrophilin/CL-1, sea urchin ...
 1040-1079 9.85e-06

G-protein-coupled receptor proteolytic site domain; Present in latrophilin/CL-1, sea urchin REJ and polycystin.


Pssm-ID: 197639  Cd Length: 49  Bit Score: 43.92  E-value: 9.85e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|.
gi 1039789995  1040 TQCYFWDRYNRTWKSDGCQVGPKS-TIlkTQCLCDHLTFFS 1079
Cdd:smart00303    3 PICVFWDESSGEWSTRGCELLETNgTH--TTCSCNHLTTFA 41
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
203-598 9.85e-06

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 50.03  E-value: 9.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSppqvtsatsASSSPPQ-----GTSDTPASSS 277
Cdd:COG5164     21 AGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQ---------GATGPAQnqggtTPAQNQGGTR 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  278 PPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSP--PQVTSATSASSSPPQGTSDTPASSS 355
Cdd:COG5164     92 PAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPpgPGSTGPGGSTTPPGDGGSTTPPGPG 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  356 PPQGTLDTPSSSSPPQGTSDTPassSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATlvsSSPPQVTSETPASSSPT 435
Cdd:COG5164    172 GSTTPPDDGGSTTPPNKGETGT---DIPTGGTPRQGPDGPVKKDDKNGKGNPPDDRGGKT---GPKDQRPKTNPIERRGP 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  436 QVTSETPASSSPTQvTSDTPASNSPPQGTSDTPgfSSPTQVTTATL---VSSSPPQVTSDTPASSSPPQVTSDTPASSSP 512
Cdd:COG5164    246 ERPEAAALPAELTA-LEAENRAANPEPATKTIP--ETTTVKDLATVlgkKGSDLVTNLMKKGKGTNINAALDFETAATIA 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  513 P--QVTSETPASSSP-PQVTSDTSASISPPQVISDTPASSSPPQVTSetpASSSPTNMTSDTPASSSPTNMTSDTPAS-- 587
Cdd:COG5164    323 LegNVITEKEIEADImETVTTEEQETDSLLEETPPVPVVMGHVDHGK---TSLLDAIRHSDVTDGEVGTISQHIGAYTvq 399

                          410
                   ....*....|..
gi 1039789995  588 -SSPTNMTSDTP 598
Cdd:COG5164    400 iAGTPITFLDTP 411
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
224-422 1.08e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 49.75  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  224 TGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSS 303
Cdd:COG3469     12 AGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  304 PPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSS--SSPPQGTSDTPASSS 381
Cdd:COG3469     92 TSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSgtETATGGTTTTSTTTT 171

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1039789995  382 PPQGTSETPASNSPPQGTSETPGFSSPP-QVTTATLVSSSPP 422
Cdd:COG3469    172 TTSASTTPSATTTATATTASGATTPSATtTATTTGPPTPGLP 213
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 349-601 1.39e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.91  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  349 DTPASSSPPqgtlDTPSSSSP-PQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSE 427
Cdd:NF033609   540 DKPVVPEQP----DEPGEIEPiPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASD 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPTQVTSDtpaSNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTP 507
Cdd:NF033609   616 SDSASDSDSASDSDSASDSDSASDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 692

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  508 ASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASS-SPTNMTSDTPA 586
Cdd:NF033609   693 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDS 772

                          250
                   ....*....|....*.
gi 1039789995  587 -SSSPTNMTSDTPASS 601
Cdd:NF033609   773 dSDSDSDSDSDSDSDS 788
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
319-547 1.42e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 1.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  319 QGTSDTPASSSPPQVTSATSASSSPPQGTSdTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQG 398
Cdd:PRK12323   368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAP-APAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG 446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  399 TSETPgfSSPPQVTTATlvsSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPtqvTT 478
Cdd:PRK12323   447 APAPA--PAPAAAPAAA---ARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDA---AP 518

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPqvtsDTSASISPPQVISDTPA 547
Cdd:PRK12323   519 AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPP----RASASGLPDMFDGDWPA 583
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
356-586 1.43e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 49.49  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  356 PPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPT 435
Cdd:PRK12323   365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  436 QVTSETPASSSPTQVTSDTPASnSPPQGTSDTPGFSSPTQVTTATlvssSPPQVTSDTPASSSPPQVTSDTPASSSPPQV 515
Cdd:PRK12323   445 GGAPAPAPAPAAAPAAAARPAA-AGPRPVAAAAAAAPARAAPAAA----PAPADDDPPPWEELPPEFASPAPAQPDAAPA 519

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  516 TSETPASSSPPQVTSDTSASISPPQvisdtPASSSPPQVTSETPASSSPTnmTSDTPASSSPTNMTSDTPA 586
Cdd:PRK12323   520 GWVAESIPDPATADPDDAFETLAPA-----PAAAPAPRAAAATEPVVAPR--PPRASASGLPDMFDGDWPA 583
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 485-636 1.71e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 49.32  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  485 SPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSE---TPASSSPPQVTSDTSASISPPQvisDTPASSSPPQVTSETPAS 561
Cdd:PRK08691   379 SPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAaamPSEGKTAGPVSNQENNDVPPWE---DAPDEAQTAAGTAQTSAK 455

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  562 SSPTNMTSDTPASSSPT-NMTSDTPASSSPTNMTSDTPASSSP-PWPVITEVTRPESTIPAgrslANITSKAQEDSP 636
Cdd:PRK08691   456 SIQTASEAETPPENQVSkNKAADNETDAPLSEVPSENPIQATPnDEAVETETFAHEAPAEP----FYGYGFPDNDCP 528
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 439-631 1.94e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 49.52  E-value: 1.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  439 SETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQvtSDTPASSSPPQVTSE 518
Cdd:NF033609    33 SSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVAQNPAQ--QETTQSASTNATTEE 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  519 TPASSSPPQVTSDTSASISPPQViSDTPASSSPPQVTSETpaSSSPTNMTSDTpasSSPTN--------MTSDTPASSSP 590
Cdd:NF033609   111 TPVTGEATTTATNQANTPATTQS-SNTNAEELVNQTSNET--TSNDTNTVSSV---NSPQNstnaenvsTTQDTSTEATP 184

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1039789995  591 TNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKA 631
Cdd:NF033609   185 SNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADA 225
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 371-484 1.97e-05

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 49.32  E-value: 1.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  371 QGTSDTPASSSP--PQGTSETPAS-NSPPQGTSeTPGFSSPPQVTTATLV--SSSPPQVTSETPASSSPTQVTSETPASS 445
Cdd:PLN02217   545 QGDAWIPGKGVPyiPGLFAGNPGStNSTPTGSA-ASSNTTFSSDSPSTVVapSTSPPAGHLGSPPATPSKIVSPSTSPPA 623

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995  446 SPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSS 484
Cdd:PLN02217   624 SHLGSPSTTPSSPESSIKVASTETASPESSIKVASTESS 662
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
203-665 2.04e-05

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 48.87  E-value: 2.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPA----SSSPPQvtsatsasssppQGTSDTPASSSp 278
Cdd:COG5164      3 LYGPGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAqnqgSTTPAG------------NTGGTRPAGNQ- 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  279 pqvtsatsASSSPPQ-----GTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPAS 353
Cdd:COG5164     70 --------GATGPAQnqggtTPAQNQGGTRPAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGG 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  354 SSPPQGTLDTPSSSSPPQGTSdtpASSSPPQGTSETPASNSPPQGTSETPGFSSPPqvttatlvsssPPQVTSETPASSS 433
Cdd:COG5164    142 STPPGPGSTGPGGSTTPPGDG---GSTTPPGPGGSTTPPDDGGSTTPPNKGETGTD-----------IPTGGTPRQGPDG 207

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  434 PTQVTSETPASSSPTQVTSDTPAsnSPPQGTSDTPGFSSPTQVTTATLVSSSPPQvtSDTPASSSPPQVTSDTPASSSP- 512
Cdd:COG5164    208 PVKKDDKNGKGNPPDDRGGKTGP--KDQRPKTNPIERRGPERPEAAALPAELTAL--EAENRAANPEPATKTIPETTTVk 283

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  513 PQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPP--QVTSETPASSSPT-NMTSDTPASSSPTNMTSDTPasss 589
Cdd:COG5164    284 DLATVLGKKGSDLVTNLMKKGKGTNINAALDFETAATIALegNVITEKEIEADIMeTVTTEEQETDSLLEETPPVP---- 359

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  590 PTNMTSDTPASSSPPWPVITEVTRPESTIP-----AGRSLANITSKAQEDSPLGVISTHPQMSFQSSTSQQALDETAGER 664
Cdd:COG5164    360 VVMGHVDHGKTSLLDAIRHSDVTDGEVGTIsqhigAYTVQIAGTPITFLDTPGFESFTAMAMRVAQITDIAILVVAADDG 439


                   .
gi 1039789995  665 V 665
Cdd:COG5164    440 D 440
rne PRK10811
ribonuclease E; Reviewed
 474-620 2.10e-05

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 49.27  E-value: 2.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  474 TQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSP----------PQVTSETPASSSPPQVTSDTSASIS-----P 538
Cdd:PRK10811   848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPvveavaevveEPVVVAEPQPEEVVVVETTHPEVIAapvteQ 927

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  539 PQVISDTPASssppqVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTI 618
Cdd:PRK10811   928 PQVITESDVA-----VAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVA 1002


                   ..
gi 1039789995  619 PA 620
Cdd:PRK10811  1003 PA 1004
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
239-551 2.71e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 48.69  E-value: 2.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  239 PPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPqvtsatsassspp 318
Cdd:PRK07003   360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAP------------- 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  319 qgtsdtPASSSPPQvtsatsasssppQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQG 398
Cdd:PRK07003   427 ------PAAPAPPA------------TADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  399 TSEtpgfSSPPqvttATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPqgtSDTPGFSSPTQV-T 477
Cdd:PRK07003   489 AFE----PAPR----AAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPA---ARAGGAAAALDVlR 557

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039789995  478 TATLVSSSPPQVTSDTPASSSPPQVTSDTPAsssPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSP 551
Cdd:PRK07003   558 NAGMRVSSDRGARAAAAAKPAAAPAAAPKPA---APRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPP 628
PPE COG5651
PPE-repeat protein [Function unknown];
363-587 2.87e-05

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 47.97  E-value: 2.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 TPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGtsetpGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETP 442
Cdd:COG5651    165 TPFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFANL-----GLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAAG 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  443 ASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPAS 522
Cdd:COG5651    240 AAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAA 319

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  523 SSPP-QVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPAS 587
Cdd:COG5651    320 GATGaGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 203-502 2.88e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.42  E-value: 2.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  203 PIDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVT 282
Cdd:pfam17823  153 NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVG 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  283 SATSASssppqGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPpQVTSATSASSSPPQGTSDTPASSSPPQgtld 362
Cdd:pfam17823  233 NSSPAA-----GTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDP-HARRLSPAKHMPSDTMARNPAAPMGAQ---- 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 tpSSSSPPQGTSDTPASSSPPQGTSEtpasnspPQGTSETPGFSSPPQVTTATLVSSSPPQvTSETPASSSPTQVTSETP 442
Cdd:pfam17823  303 --AQGPIIQVSTDQPVHNTAGEPTPS-------PSNTTLEPNTPKSVASTNLAVVTTTKAQ-AKEPSASPVPVLHTSMIP 372

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  443 --ASSSPTQVTSDTPasnsPPQGTSDTPGFSSPTQVTT-ATLVSSSppqvTSDTPASSSPPQV 502
Cdd:pfam17823  373 evEATSPTTQPSPLL----PTQGAAGPGILLAPEQVATeATAGTAS----AGPTPRSSGDPKT 427
DUF4045 pfam13254
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ...
 320-499 3.18e-05

Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.


Pssm-ID: 433066 [Multi-domain]  Cd Length: 415  Bit Score: 48.24  E-value: 3.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  320 GTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPasnspPQGT 399
Cdd:pfam13254  190 ASVDLGRPNSFKEVTPVGLMRSPAPGGHSKSPSVSGISADSSPTKEEPSEEADTLSTDKEQSPAPTSASEP-----PPKT 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  400 SETPGFSSPPQVTTaTLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTA 479
Cdd:pfam13254  265 KELPKDSEEPAAPS-KSAEASTEKKEPDTESSPETSSEKSAPSLLSPVSKASIDKPLSSPDRDPLSPKPKPQSPPKDFRA 343

                          170       180
                   ....*....|....*....|
gi 1039789995  480 TLVSSsppQVTSDTPASSSP 499
Cdd:pfam13254  344 NLRSR---EVPKDKSKKDEP 360
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 479-668 3.25e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.42  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  479 ATLVSSSPPQVTSDTPASS-SPPQVTSDTpassSPPQVTSETPASSSPpqvTSDTSASISPPqvisdTPASSSPPQVTSE 557
Cdd:pfam17823   62 AATAAPAPVTLTKGTSAAHlNSTEVTAEH----TPHGTDLSEPATREG---AADGAASRALA-----AAASSSPSSAAQS 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  558 TPASSS-PTNMTSDTPASSSPTnmTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAqedsP 636
Cdd:pfam17823  130 LPAAIAaLPSEAFSAPRAAACR--ANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSA----P 203

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1039789995  637 LGVISTHPQMSFQSSTSQQALDeTAGERVPTI 668
Cdd:pfam17823  204 ATLTPARGISTAATATGHPAAG-TALAAVGNS 234
PHA03377 PHA03377
EBNA-3C; Provisional
 167-574 3.38e-05

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 48.51  E-value: 3.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  167 KRRGAETERHMIP-----GNGPPLAMCHQPAPPElfetlcfpIDPASSAPPKATHRMTITSLTGRPQVTSdtLASSSPPQ 241
Cdd:PHA03377   541 QRSGRRQKRATPPkvspsDRGPPKASPPVMAPPS--------TGPRVMATPSTGPRDMAPPSTGPRQQAK--CKDGPPAS 610

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  242 GTSD-TPASSSP----PQVTSATSASSSPPQGTSDTP-------ASSSPPQVTSATSASSSPPQgTSDTPASSSPPQVTS 309
Cdd:PHA03377   611 GPHEkQPPSSAPrdmaPSVVRMFLRERLLEQSTGPKPksfwemrAGRDGSGIQQEPSSRRQPAT-QSTPPRPSWLPSVFV 689

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  310 ATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLdtPSSSSPPQGTSDTPASSSPPQGTSET 389
Cdd:PHA03377   690 LPSVDAGRAQPSEESHLSSMSPTQPISHEEQPRYEDPDDPLDLSLHPDQAPP--PSHQAPYSGHEEPQAQQAPYPGYWEP 767

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  390 PASNSPPQGTSETPGfssppqvtTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPG 469
Cdd:PHA03377   768 RPPQAPYLGYQEPQA--------QGVQVSSYPGYAGPWGLRAQHPRYRHSWAYWSQYPGHGHPQGPWAPRPPHLPPQWDG 839

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQvttaTLVSSSP---PQVTSDTPASSSPPQVT-SDTPASSSPPqvtsetPASSSPPQvtsdtsASISPpqVISDT 545
Cdd:PHA03377   840 SAGHGQ----DQVSQFPhlqSETGPPRLQLSQVPQLPySQTLVSSSAP------SWSSPQPR------APIRP--IPTRF 901

                          410       420
                   ....*....|....*....|....*....
gi 1039789995  546 PASSSPPQVTSETPASSSPTNMTSDTPAS 574
Cdd:PHA03377   902 PPPPMPLQDSMAVGCDSSGTACPSMPFAS 930
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
508-595 3.56e-05

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 48.31  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  508 ASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDT-PASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPA 586
Cdd:PRK11907    18 LTASNPKLAQAEEIVTTTPATSTEAEQTTPVESDATEEaDNTETPVAATTAAEAPSSSETAETSDPTSEATDTTTSEART 97


                   ....*....
gi 1039789995  587 SSSPTNMTS 595
Cdd:PRK11907    98 VTPAATETS 106
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 403-558 4.32e-05

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 48.16  E-value: 4.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  403 PGFSSPPQVTTATLVSSSPPQVTSETPASSspTQVTSETPASSSPTQ---VTSDTPASNSPPQGTSdTPGFSSPTQVTTA 479
Cdd:PLN02217   514 PGAAITKRVTWPGIKKLSDEEILKFTPAQY--IQGDAWIPGKGVPYIpglFAGNPGSTNSTPTGSA-ASSNTTFSSDSPS 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  480 TLV--SSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPqVTSDTSASISPPQVISDTPASSSPPQVTSE 557
Cdd:PLN02217   591 TVVapSTSPPAGHLGSPPATPSKIVSPSTSPPASHLGSPSTTPSSPESS-IKVASTETASPESSIKVASTESSVSMVSMS 669


                   .
gi 1039789995  558 T 558
Cdd:PLN02217   670 T 670
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
534-633 4.32e-05

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 48.31  E-value: 4.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  534 ASISPPQVISDTPASSSPPQvTSETPASSSPTnmtsDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTR 613
Cdd:PRK11907    18 LTASNPKLAQAEEIVTTTPA-TSTEAEQTTPV----ESDATEEADNTETPVAATTAAEAPSSSETAETSDPTSEATDTTT 92

                           90       100
                   ....*....|....*....|
gi 1039789995  614 PEStiPAGRSLANITSKAQE 633
Cdd:PRK11907    93 SEA--RTVTPAATETSKPVE 110
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
413-520 4.62e-05

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 47.43  E-value: 4.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  413 TATLVSSSPPQVTSETPASSSPTQV--TSETPASSSPTQVTSDTPASNsppQGTSDTPGFSSPTQVTTATLVSSSPPQVT 490
Cdd:PRK13335    55 TAGANSATTQAANTRQERTPKLEKApnTNEEKTSASKIEKISQPKQEE---QKSLNISATPAPKQEQSQTTTESTTPKTK 131

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1039789995  491 SDTPASSSPPQ----VTSDTPASSSPPQVTSE-TP 520
Cdd:PRK13335   132 VTTPPSTNTPQpmqsTKSDTPQSPTIKQAQTDmTP 166
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
487-666 5.25e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 47.92  E-value: 5.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  487 PQVTSDT-PASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPT 565
Cdd:PRK07003   360 PAVTGGGaPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  566 N--MTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVISTH 643
Cdd:PRK07003   440 DdaADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519

                          170       180
                   ....*....|....*....|...
gi 1039789995  644 PQMSFQSSTSQQALDETAGERVP 666
Cdd:PRK07003   520 DAPAAAAPPAPEARPPTPAAAAP 542
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 395-532 5.26e-05

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 47.78  E-value: 5.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  395 PPQGTSETPG-FSSPPQVTTATLVSSSPPQVTSETpaSSSPTqvTSETPASSsptqvtsdtpasnsPPQGTSDTPGFSSP 473
Cdd:PLN02217   551 PGKGVPYIPGlFAGNPGSTNSTPTGSAASSNTTFS--SDSPS--TVVAPSTS--------------PPAGHLGSPPATPS 612

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  474 TQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPaSSSPPQVTSETPASSSPPQVTSDT 532
Cdd:PLN02217   613 KIVSPSTSPPASHLGSPSTTPSSPESSIKVASTE-TASPESSIKVASTESSVSMVSMST 670
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 476-616 5.35e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.50  E-value: 5.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  476 VTTATLVSSSPPQVTSDTPASSSPPQvtsDTPASSSPPQVTSETPASSSPPQvtsdtsASISPPQVISDTPASSSPPQVT 555
Cdd:PRK14950   355 VIEALLVPVPAPQPAKPTAAAPSPVR---PTPAPSTRPKAAAAANIPPKEPV------RETATPPPVPPRPVAPPVPHTP 425

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  556 SETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASssppWPVITEVTRPES 616
Cdd:PRK14950   426 ESAPKLTRAAIPVDEKPKYTPPAPPKEEEKALIADGDVLEQLEAI----WKQILRDVPPRS 482
motB PRK12799
flagellar motor protein MotB; Reviewed
 477-595 5.42e-05

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 47.40  E-value: 5.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  477 TTATLVSSSPPQVTSDTPASSSPPqvtsdTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTS 556
Cdd:PRK12799   307 SSAVTQSSAITPSSAAIPSPAVIP-----SSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPMST 381

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995  557 ETPASSSPTNMtsdTPASSSPTNMTSDTPASSSPTNMTS 595
Cdd:PRK12799   382 TETQQSSTGNI---TSTANGPTTSLPAAPASNIPVSPTS 417
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
448-585 5.74e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 47.46  E-value: 5.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  448 TQVTSDTPASNSPPQGTSdtPGFS---SPTQVTTATLVSSSPPQvTSDTPASSSPPQVTsdtPASSSPPQVtSETPASSS 524
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIK--PVFTqpaAAPQPSAAAAASPSPSQ-SSAAAQPSAPQSAT---QPAGTPPTV-SVDPPAAV 435

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  525 PPQVTSDTSASISPPQVISDTPASSSppQVTSETPASSSPTNMTSDTPASSSPTNMTSDTP 585
Cdd:PRK14971   436 PVNPPSTAPQAVRPAQFKEEKKIPVS--KVSSLGPSTLRPIQEKAEQATGNIKEAPTGTQK 494
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 472-564 5.98e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.50  E-value: 5.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  472 SPTQVTTATLVSSSPPQVTsDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSAsisPPQVISDTPASSSP 551
Cdd:PRK14950   362 PVPAPQPAKPTAAAPSPVR-PTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPH---TPESAPKLTRAAIP 437

                           90
                   ....*....|...
gi 1039789995  552 PQVTSETPASSSP 564
Cdd:PRK14950   438 VDEKPKYTPPAPP 450
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 437-634 6.18e-05

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 46.39  E-value: 6.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  437 VTSETPAS--SSPTQVTSDTPASNSPPQGTSDTPG----------FSSPTQVTTATLVSSSPPQVTSDTPASSSP-PQVT 503
Cdd:PHA02682    17 VLADTSSSlfTKCPQATIPAPAAPCPPDADVDPLDkysvkeagryYQSRLKANSACMQRPSGQSPLAPSPACAAPaPACP 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  504 SDTPASSSPpQVTSETPASSSPPQvtsdTSASISPPQVISDT--PASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMT 581
Cdd:PHA02682    97 ACAPAAPAP-AVTCPAPAPACPPA----TAPTCPPPAVCPAParPAPACPPSTRQCPPAPPLPTPKPAPAAKPIFLHNQL 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  582 S--DTPASSSPTNMTSdtPASSsppwPVItEVTRPESTIPAGRSLANITSKAQED 634
Cdd:PHA02682   172 PppDYPAASCPTIETA--PAAS----PVL-EPRIPDKIIDADNDDKDLIKKELAD 219
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
405-521 6.44e-05

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 47.54  E-value: 6.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  405 FSSPPQVTTATLVSSSPPQVTSETPASssptqvtseTPASSSPTQVTSDTPASNSppqGTSDTPGFSSPTQVTTATLVSS 484
Cdd:PRK11907     6 FSKSAVALTLALLTASNPKLAQAEEIV---------TTTPATSTEAEQTTPVESD---ATEEADNTETPVAATTAAEAPS 73

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1039789995  485 SPPQVTSDTPASSSPPQVTSDTPasSSPPQVTSETPA 521
Cdd:PRK11907    74 SSETAETSDPTSEATDTTTSEAR--TVTPAATETSKP 108
Metaviral_G pfam09595
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 367-517 6.92e-05

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 45.33  E-value: 6.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  367 SSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSS 446
Cdd:pfam09595   32 SLILIGESNKEAALIITDIIDININKQHPEQEHHENPPLNEAAKEAPSESEDAPDIDPNNQHPSQDRSEAPPLEPAAKTK 111

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  447 PTQV----TSDTPASNSPPQGTSdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTS 517
Cdd:pfam09595  112 PSEHepanPPDASNRLSPPDAST-----AAIREARTFRKPSTGKRNNPSSAQSDQSPPRANHEAIGRANPFAMSS 181
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 414-621 7.02e-05

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 47.52  E-value: 7.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  414 ATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQV-----TSDTPASNSP-----PQGTSDTPGFSSPTQVTTATLVS 483
Cdd:pfam08580  422 ATLVANKTPGSSPPSSVIMTPVNKGSKTPSSRRGSSFdfgssSERVINSKLRresklPQIASTLKQTKRPSKIPRASPNH 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  484 SSPPQVTSDTPASSSPpqvtsdTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSS 563
Cdd:pfam08580  502 SGFLSTPSNTATSETP------TPALRPPSRPQPPPPGNRPRWNASTNTNDLDVGHNFKPLTLTTPSPTPSRSSRSSSTL 575

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  564 PTNMTSDTPASSSPT-NMTSDTPASSSPTNMTSDTPASSSPPWPVITEVTRPESTIPAG 621
Cdd:pfam08580  576 PPVSPLSRDKSRSPApTCRSVSRASRRRASRKPTRIGSPNSRTSLLDEPPYPKLTLSKG 634
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
470-569 7.13e-05

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 47.54  E-value: 7.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSPPqvTSDTPASSSPPQVTSET---PASSSPPQVTSDTSASISPPQVISDTP 546
Cdd:PRK11907     6 FSKSAVALTLALLTASNPKLAQAEEIVTTTP--ATSTEAEQTTPVESDATeeaDNTETPVAATTAAEAPSSSETAETSDP 83

                           90       100
                   ....*....|....*....|...
gi 1039789995  547 ASSSPPQVTSETPASSSPTNMTS 569
Cdd:PRK11907    84 TSEATDTTTSEARTVTPAATETS 106
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 468-628 7.51e-05

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 47.39  E-value: 7.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  468 PGFSSPTQVTTATLVSSSPPQVTSDTPASssppQVTSDT--PASSSP--PQVTSETPASSsppqvTSDTSASISPpqviS 543
Cdd:PLN02217   514 PGAAITKRVTWPGIKKLSDEEILKFTPAQ----YIQGDAwiPGKGVPyiPGLFAGNPGST-----NSTPTGSAAS----S 580

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  544 DTPASSSPPQvTSETPASSSPTNMTSDTPASSSpTNMTSDTPASSSPTNMTSDTPAS-SSPPWPVITEVTRPESTIPAGR 622
Cdd:PLN02217   581 NTTFSSDSPS-TVVAPSTSPPAGHLGSPPATPS-KIVSPSTSPPASHLGSPSTTPSSpESSIKVASTETASPESSIKVAS 658


                   ....*.
gi 1039789995  623 SLANIT 628
Cdd:PLN02217   659 TESSVS 664
Caprin-1_C pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is ...
 444-651 8.19e-05

Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteriztic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.


Pssm-ID: 463522 [Multi-domain]  Cd Length: 320  Bit Score: 46.32  E-value: 8.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  444 SSSPTQVTSDTPASNSPPqgTSDTPGFSSPTQVTTATLVSSSPPqVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASS 523
Cdd:pfam12287   32 SAQPPSQSPDLSQMVCPP--ASPEQRLSQQSDVLQQPEQTQVSP-VSPSSNACASSGSEYQFHTSEPPQPEAIDPIQSSM 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  524 SPPQVTSDTSASISPpqvisdtpasSSPPQVTSETPASSSPTNMTSdTPASSSPT--NMTSDTP-ASSSPTNMTSDTPAS 600
Cdd:pfam12287  109 SLPSELAPPSPPLSP----------ASQPQVFQSKPASSSGINVNA-APFQSMQTvfNVNAPVPpRNEQELKESSQYSSG 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  601 SSPPWPVITEVTRPESTIPAGRSLANITSKAQEDSPLGVISTHpqMSFQSS 651
Cdd:pfam12287  178 YNQSFSSQSTQTVPQCQLPSEQLEQTVVGAYHPDGTIQVSNGH--LAFYPA 226
PHA03255 PHA03255
BDLF3; Provisional
 363-532 8.22e-05

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 45.67  E-value: 8.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 TPSSSSPPQGTSDTPASSSppqgTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETP 442
Cdd:PHA03255    25 TSSGSSTASAGNVTGTTAV----TTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVPTTSNASTI 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  443 ASSspTQVTSDTPASNSPPQGTsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTpaSSSPPQVTSETPAS 522
Cdd:PHA03255   101 NVT--TKVTAQNITATEAGTGT------STGVTSNVTTRSSSTTSATTRITNATTLAPTLSSKG--TSNATKTTAELPTV 170

                          170
                   ....*....|
gi 1039789995  523 SSPPQVTSDT 532
Cdd:PHA03255   171 PDERQPSLSY 180
PLAT_LOX cd01753
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they ...
 1152-1253 9.34e-05

PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and plasma lipoproteins. Both types of enzymes are cytosolic but need this domain to access their sequestered membrane or micelle bound substrates.


Pssm-ID: 238851  Cd Length: 113  Bit Score: 43.07  E-value: 9.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1152 YLIQVYTGYRRRAATTAKVVITLYGSEGHSEPhHLCDPEKTVFERGALDVFLLSTGSWLGDLHGLRLWHDNSGDSPSWYV 1231
Cdd:cd01753      3 YKVTVATGSSLFAGTDDYIYLTLVGTAGESEK-QLLDRPGYDFERGAVDEYKVKVPEDLGELLLVRLRKRKYLLFDAWFC 81

                           90       100
                   ....*....|....*....|..
gi 1039789995 1232 SQVIVSDmTTRKKWHFQCNCWL 1253
Cdd:cd01753     82 NYITVTG-PGGDEYHFPCYRWI 102
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
225-461 9.43e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 47.15  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  225 GRPQVTSDTLASSSPPQGTSDTPASSSP-PQVTSATSASSSPPQGTSDTPASSSppQVTSATSASSSPPQGTSDTPASSS 303
Cdd:PRK07003   383 PGARAAAAVGASAVPAVTAVTGAAGAALaPKAAAAAAATRAEAPPAAPAPPATA--DRGDDAADGDAPVPAKANARASAD 460

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  304 PPqvTSATSASSSPPQGTSDTPASSSPPQVTSATSasssppqgTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPP 383
Cdd:PRK07003   461 SR--CDERDAQPPADSGSASAPASDAPPDAAFEPA--------PRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAP 530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  384 QGTSETPASNSPP---------------------QGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETP 442
Cdd:PRK07003   531 EARPPTPAAAAPAaraggaaaaldvlrnagmrvsSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPP 610

                          250
                   ....*....|....*....
gi 1039789995  443 ASSSPTQVTSDTPASnSPP 461
Cdd:PRK07003   611 NGAARAEQAAESRGA-PPP 628
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 482-620 9.78e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 46.78  E-value: 9.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  482 VSSSPPQVTSDTPASssppQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPAS 561
Cdd:PRK07994   367 EPEVPPQSAAPAASA----QATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSE 442

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  562 SSPTNMTsdTPASSSPTNMTSDTPASSSPTNMTSDTPA----SSSPPWPVITEVTRPESTIPA 620
Cdd:PRK07994   443 PAAASRA--RPVNSALERLASVRPAPSALEKAPAKKEAyrwkATNPVEVKKEPVATPKALKKA 503
PLAT_RAB6IP1 cd01757
PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains ...
 1210-1262 9.79e-05

PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains consists of an eight stranded beta-barrel. In RabIP1 this domain may participate in lipid-mediated modulation of Rab6IP1's function via it's generally proposed function of mediating interaction with lipids or membrane bound proteins.


Pssm-ID: 238855  Cd Length: 114  Bit Score: 43.30  E-value: 9.79e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995 1210 LGDLHGLRLWHDNSGDSPSWYVSQVIVSDMTTRKKWHFQCNCWL-------AVDLGNCER 1262
Cdd:cd01757     52 LGKLTTVQIGHDNSGLLAKWLVEYVMVRNEITGHTYKFPCGRWLgegvddgNGEDGSLER 111
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 411-549 1.10e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 46.73  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  411 VTTATLVSSSPPQvtSETPASSSPTQVTsETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATlvsSSPPQVT 490
Cdd:PRK14950   355 VIEALLVPVPAPQ--PAKPTAAAPSPVR-PTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPV---PHTPESA 428

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  491 SDTPASSSPPQVtsdTPASSSPPQVTSETPASSSPPQVTSDTSASIspPQVISDTPASS 549
Cdd:PRK14950   429 PKLTRAAIPVDE---KPKYTPPAPPKEEEKALIADGDVLEQLEAIW--KQILRDVPPRS 482
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 322-589 1.10e-04

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 46.75  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  322 SDTPASSSPPQvtsatsasssppqgTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQG-TS 400
Cdd:pfam08580  427 NKTPGSSPPSS--------------VIMTPVNKGSKTPSSRRGSSFDFGSSSERVINSKLRRESKLPQIASTLKQTKrPS 492

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  401 ETPGFSSPPQVTtatlVSSSPPQVTSETPA-SSSPTQVTSETPASSSPTQVTSDTPASNSPPQ-GTSDTPGFSSPTQVTT 478
Cdd:pfam08580  493 KIPRASPNHSGF----LSTPSNTATSETPTpALRPPSRPQPPPPGNRPRWNASTNTNDLDVGHnFKPLTLTTPSPTPSRS 568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSPpqVTSDTPASSSPPQVTSETPASSSPPQvtsdtsasiSPPQVISDTPASSSP-PQVTSE 557
Cdd:pfam08580  569 SRSSSTLPPVSPLSRDKSRSP--APTCRSVSRASRRRASRKPTRIGSPN---------SRTSLLDEPPYPKLTlSKGLPR 637

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1039789995  558 TPASSSPTNMTSDTPASSSPTNMTSDTPASSS 589
Cdd:pfam08580  638 TPRNRQSYAGTSPSRSVSVSSGLGPQTRPGTS 669
PHA03255 PHA03255
BDLF3; Provisional
 347-511 1.20e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 45.28  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSppqgtldTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTseTPGFSSPPQVTTATLVSSSPPQVTS 426
Cdd:PHA03255    25 TSSGSSTAS-------AGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITT--TAILSTNTTTVTSTGTTVTPVPTTS 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 ETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTpgfSSPTQVTTATLVSSSPPQVTSD--TPASSSPPQVTS 504
Cdd:PHA03255    96 NASTINVTTKVTAQNITATEAGTGTSTGVTSNVTTRSSSTT---SATTRITNATTLAPTLSSKGTSnaTKTTAELPTVPD 172


                   ....*..
gi 1039789995  505 DTPASSS 511
Cdd:PHA03255   173 ERQPSLS 179
Caprin-1_C pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is ...
 366-498 1.27e-04

Cytoplasmic activation/proliferation-associated protein-1 C term; This family of proteins is found in eukaryotes. Proteins in this family are typically between 343 and 708 amino acids in length. This family is the C terminal region of caprin-1. Caprin-1 is a protein involved in regulating cellular proliferation. In mutated phenotypes, the G1 phase of the cell cycle is greatly lengthened, impairing normal proliferation. The C terminal region of caprin-1 contains RGG motifs which are characteriztic of RNA binding domains. It is possible that caprin-1 functions through an RNA binding mechanism.


Pssm-ID: 463522 [Multi-domain]  Cd Length: 320  Bit Score: 45.94  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  366 SSSPPQGTSDTPASSSPPQgtsetpasnSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASS 445
Cdd:pfam12287   32 SAQPPSQSPDLSQMVCPPA---------SPEQRLSQQSDVLQQPEQTQVSPVSPSSNACASSGSEYQFHTSEPPQPEAID 102

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  446 SPtqvtsdtPASNSPPqgtsdtpgfSSPTQvTTATLVSSSPPQVTSDTPASSS 498
Cdd:pfam12287  103 PI-------QSSMSLP---------SELAP-PSPPLSPASQPQVFQSKPASSS 138
PRK12727 PRK12727
flagellar biosynthesis protein FlhF;
358-566 1.28e-04

flagellar biosynthesis protein FlhF;


Pssm-ID: 237182 [Multi-domain]  Cd Length: 559  Bit Score: 46.52  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  358 QGTLDTPSSSSP--PQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPT 435
Cdd:PRK12727    52 QRALETARSDTPatAAAPAPAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAAEDMIAAMALRQPVSVPRQAPAAAPVR 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  436 QVTSETPAssspTQVTSDTPASNSPPQGTSDTPgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQV 515
Cdd:PRK12727   132 AASIPSPA----AQALAHAAAVRTAPRQEHALS--AVPEQLFADFLTTAPVPRAPVQAPVVAAPAPVPAIAAALAAHAAY 205

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  516 TSETPASSSPPQVTSDTS--ASISPPQVISDTPASSSPPQVTSETPASSSPTN 566
Cdd:PRK12727   206 AQDDDEQLDDDGFDLDDAlpQILPPAALPPIVVAPAAPAALAAVAAAAPAPQN 258
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
293-521 1.41e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.41  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  293 QGTSDTPASSSPPQVTSATSASSSPpqgTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQG 372
Cdd:PRK12323   368 SGGGAGPATAAAAPVAQPAPAAAAP---AAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  373 TSDTPASSSPPQgtseTPASNSPPQgtsetpgfSSPPQVTTATLVSSSPPQvtseTPASSSPTQVTSETPASSSPTQVTS 452
Cdd:PRK12323   445 GGAPAPAPAPAA----APAAAARPA--------AAGPRPVAAAAAAAPARA----APAAAPAPADDDPPPWEELPPEFAS 508

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  453 DTPASNSPPQGTSDTPGFSSP-TQVTTATLVSSSPPQVTSDTPASSSP-----PQVTSDTPASSSPPQVTSETPA 521
Cdd:PRK12323   509 PAPAQPDAAPAGWVAESIPDPaTADPDDAFETLAPAPAAAPAPRAAAAtepvvAPRPPRASASGLPDMFDGDWPA 583
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 351-448 1.43e-04

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 46.10  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSSPPQ-GTSD--TPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSE 427
Cdd:PHA03291   176 PLGEGSADGSCDPALPLSAPRlGPADvfVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPSTTIAAPQAGTTPEAEG 255

                           90       100
                   ....*....|....*....|.
gi 1039789995  428 TPASSSPTqVTSETPASSSPT 448
Cdd:PHA03291   256 TPAPPTPG-GGEAPPANATPA 275
PHA03378 PHA03378
EBNA-3B; Provisional
 410-632 1.45e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 46.60  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  410 QVTTATLVSSSPPQVTSetpASSSPTQVTSETpasssptQVTSDTPASNSPPQGTS-DTPGfssPTQVTTATLVSSSPPQ 488
Cdd:PHA03378   518 QRVMATLLPPSPPQPRA---GRRAPCVYTEDL-------DIESDEPASTEPVHDQLlPAPG---LGPLQIQPLTSPTTSQ 584

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  489 VTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPP---QVIS-DTPASSSPPQVTSETPASSSP 564
Cdd:PHA03378   585 LASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPlrmQPITfNVLVFPTPHQPPQVEITPYKP 664

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  565 T-NMTSDTPASSSPTNMTSDTPASSSPTNMTSD--TPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQ 632
Cdd:PHA03378   665 TwTQIGHIPYQPSPTGANTMLPIQWAPGTMQPPprAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRAR 735
Metaviral_G pfam09595
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 443-595 1.52e-04

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 44.17  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  443 ASSSPTQVTSDTPASNSppqgtSDTPGFSSPTQVTTATLVSSSPPqvtsdTPASSSPPQVTSDTPASSSPPQVTSETPAS 522
Cdd:pfam09595   31 ASLILIGESNKEAALII-----TDIIDININKQHPEQEHHENPPL-----NEAAKEAPSESEDAPDIDPNNQHPSQDRSE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  523 SSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSS----PTNMTSDTPAS----SSPTNMTSDTPASSSPTNMT 594
Cdd:pfam09595  101 APPLEPAAKTKPSEHEPANPPDASNRLSPPDASTAAIREARtfrkPSTGKRNNPSSaqsdQSPPRANHEAIGRANPFAMS 180


                   .
gi 1039789995  595 S 595
Cdd:pfam09595  181 S 181
PRK10856 PRK10856
cytoskeleton protein RodZ;
457-551 1.59e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 45.40  E-value: 1.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  457 SNSPPQGTSDTPgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASI 536
Cdd:PRK10856   159 GQSVPLDTSTTT--DPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAP 236

                           90
                   ....*....|....*
gi 1039789995  537 SPPQVISDTPASSSP 551
Cdd:PRK10856   237 LPTDQAGVSTPAADP 251
PRK10856 PRK10856
cytoskeleton protein RodZ;
451-538 1.60e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 45.40  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  451 TSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTS 530
Cdd:PRK10856   164 LDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAG 243


                   ....*...
gi 1039789995  531 DTSASISP 538
Cdd:PRK10856   244 VSTPAADP 251
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 427-588 1.66e-04

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 45.74  E-value: 1.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 ETPASSSPTQVTSETPASSSPTQVTS---DTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSppqvtsDTPASSSPPQVT 503
Cdd:PRK13108   280 EAPGALRGSEYVVDEALEREPAELAAaavASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVT------DEVAAESVVQVA 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  504 SDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSS--PTNMT 581
Cdd:PRK13108   354 DRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPakPDELA 433


                   ....*..
gi 1039789995  582 SDTPASS 588
Cdd:PRK13108   434 VAGPGDD 440
PRK13042 PRK13042
superantigen-like protein SSL4; Reviewed;
481-577 1.72e-04

superantigen-like protein SSL4; Reviewed;


Pssm-ID: 183854 [Multi-domain]  Cd Length: 291  Bit Score: 45.39  E-value: 1.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 LVSSSPPQVTSDTPASSSPPQVTSDTPaSSSPPQVTSETPASSspPQVTSDTSASISPPQvisDTPASSSPPQVTSETPa 560
Cdd:PRK13042    15 LLTTGVITTTTQAANATTPSSTKVEAP-QSTPPSTKVEAPQSK--PNATTPPSTKVEAPQ---QTPNATTPSSTKVETP- 87

                           90
                   ....*....|....*..
gi 1039789995  561 sSSPTnmTSDTPASSSP 577
Cdd:PRK13042    88 -QSPT--TKQVPTEINP 101
Metaviral_G pfam09595
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 418-569 1.78e-04

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 44.17  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  418 SSSPPQVTSETpASSSPTQVTSETPASSSPTQVTSD----TPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDT 493
Cdd:pfam09595   32 SLILIGESNKE-AALIITDIIDININKQHPEQEHHEnpplNEAAKEAPSESEDAPDIDPNNQHPSQDRSEAPPLEPAAKT 110

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  494 PASSSPPQVTSDTPASSSPPQVTSETPASSsppqvTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTS 569
Cdd:pfam09595  111 KPSEHEPANPPDASNRLSPPDASTAAIREA-----RTFRKPSTGKRNNPSSAQSDQSPPRANHEAIGRANPFAMSS 181
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
513-714 1.78e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.92  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  513 PQVTSETPASSSPPQVTSD-TSASISPPQVISDTPASSSPPQvTSETPASSSPTNMTsdTPASSSPTNMTSdtPASSSPT 591
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKPvFTQPAAAPQPSAAAAASPSPSQ-SSAAAQPSAPQSAT--QPAGTPPTVSVD--PPAAVPV 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  592 NMTSDTPASSSPPwpviteVTRPESTIPagrslaniTSKAqedSPLGVISTHPQmsfQSSTSQQALDETAgerVPTIPDF 671
Cdd:PRK14971   438 NPPSTAPQAVRPA------QFKEEKKIP--------VSKV---SSLGPSTLRPI---QEKAEQATGNIKE---APTGTQK 494

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1039789995  672 QAHSEFQkacaiLQRL-RDFLPTSPtSAQVSVANLLIDLSEQLL 714
Cdd:PRK14971   495 EIFTEED-----LQYYwQEFAGTRP-QEEKALKETMINCRPKLL 532
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 494-656 1.80e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.32  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  494 PASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQvisDTPASSSPPQVTSETPASSSPTNMTSDTPA 573
Cdd:PHA03307    22 PRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPP---TGPPPGPGTEAPANESRSTPTWSLSTLAPA 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  574 SSSPTNmtSDTPASSSPTNMTSDTPASSSP---PWPVITEVTRPE-STIPAGRSLANITSKAQEDSPLGVISTHPQMSFQ 649
Cdd:PHA03307    99 SPAREG--SPTPPGPSSPDPPPPTPPPASPppsPAPDLSEMLRPVgSPGPPPAASPPAAGASPAAVASDAASSRQAALPL 176


                   ....*..
gi 1039789995  650 SSTSQQA 656
Cdd:PHA03307   177 SSPEETA 183
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 231-576 1.80e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 46.06  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  231 SDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSA 310
Cdd:NF033609   571 SDSSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDS 650

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  311 TSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETP 390
Cdd:NF033609   651 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 730

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  391 ASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPA-SNSPPQGTSDTPG 469
Cdd:NF033609   731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDS 810

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  470 FSSPTQVTTATLVSSSPPQVTSDTPASSSppqvtSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPqvisDTPASS 549
Cdd:NF033609   811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSD-----SDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPP----NSPKNG 881

                          330       340
                   ....*....|....*....|....*...
gi 1039789995  550 SPPQVTSETPASSSPTNMT-SDTPASSS 576
Cdd:NF033609   882 TNASNKNEAKDSKEPLPDTgSEDEANTS 909
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 426-565 1.81e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 45.71  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  426 SETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPG--FSSPTQVTTATLVSSSPPQVTSDTPA-SSSPPQV 502
Cdd:PTZ00436   208 AAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAkaAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAK 287

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  503 TSDTPASSSppqvTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPT 565
Cdd:PTZ00436   288 AAAPPAKAA----AAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAA 346
PRK10856 PRK10856
cytoskeleton protein RodZ;
361-450 1.83e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 45.40  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  361 LDTPSSSSP-PQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTS 439
Cdd:PRK10856   164 LDTSTTTDPaTTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAG 243

                           90
                   ....*....|.
gi 1039789995  440 ETPASSSPTQV 450
Cdd:PRK10856   244 VSTPAADPNAL 254
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
321-469 2.09e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 45.42  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  321 TSDTPASSSPPQ----VTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPqgTSDTPASSSPPQGTSETPASNSPP 396
Cdd:pfam05539  191 SQVTPQSQPATQghqtATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPS--GSPQHPPSTTSQDQSTTGDGQEHT 268

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  397 QGTSETPGFSSPPQVTTATLVSSSPPQVTS--ETPASSSPTQVTSeTPASSSPTQVTSDTPASNSPPQGTSDTPG 469
Cdd:pfam05539  269 QRRKTPPATSNRRSPHSTATPPPTTKRQETgrPTPRPTATTQSGS-SPPHSSPPGVQANPTTQNLVDCKELDPPK 342
PRK10856 PRK10856
cytoskeleton protein RodZ;
522-603 2.34e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 45.02  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  522 SSSPPQVTSDTSASISPPQVISDTPASSSP--PQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPA 599
Cdd:PRK10856   168 TTTDPATTPAPAAPVDTTPTNSQTPAVATApaPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVSTP 247


                   ....
gi 1039789995  600 SSSP 603
Cdd:PRK10856   248 AADP 251
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 468-591 2.45e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.48  E-value: 2.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  468 PGFSSPTQVT--TATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTsdtsASISPPQVISDT 545
Cdd:PRK14951   366 PAAAAEAAAPaeKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAP----AAAAPAAAPAAA 441

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1039789995  546 PASSSPPQVTSETPAS--SSPTNMTSDTPASSSPTNMTSDTPASSSPT 591
Cdd:PRK14951   442 PAAVALAPAPPAQAAPetVAIPVRVAPEPAVASAAPAPAAAPAAARLT 489
PHA03255 PHA03255
BDLF3; Provisional
 399-559 2.58e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 44.12  E-value: 2.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  399 TSETPGFSSPPQVTTATLVSSSPPQvTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSppqGTSDTPGFSSPTQVTT 478
Cdd:PHA03255    25 TSSGSSTASAGNVTGTTAVTTPSPS-ASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTST---GTTVTPVPTTSNASTI 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSPPQVTSD--TPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTS 556
Cdd:PHA03255   101 NVTTKVTAQNITATEAGTGTSTGVTSNvtTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELPTVPDERQPSLSY 180


                   ...
gi 1039789995  557 ETP 559
Cdd:PHA03255   181 GLP 183
motB PRK12799
flagellar motor protein MotB; Reviewed
 373-504 2.58e-04

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 45.09  E-value: 2.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  373 TSDTPASSSPPqgTSETPASNSPPQGTSETPGfssppQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTS 452
Cdd:PRK12799   296 HGTVPVAAVTP--SSAVTQSSAITPSSAAIPS-----PAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPA 368

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  453 DTPASNSPPQGTSDTPGFSSPTQVTTATlvsSSPPQVTSDTPASSSPPQVTS 504
Cdd:PRK12799   369 AEPVNMQPQPMSTTETQQSSTGNITSTA---NGPTTSLPAAPASNIPVSPTS 417
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
487-594 2.60e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.54  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  487 PQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVisdTPASSSPPQVtSETPASSSPTN 566
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSA---TQPAGTPPTV-SVDPPAAVPVN 438

                           90       100
                   ....*....|....*....|....*...
gi 1039789995  567 MTSDTPASSSPTNMTSDTPASSSPTNMT 594
Cdd:PRK14971   439 PPSTAPQAVRPAQFKEEKKIPVSKVSSL 466
PRK13914 PRK13914
invasion associated endopeptidase;
352-588 2.86e-04

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 45.18  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  352 ASSSPPQGTLDTPSSSSPPQGTsdtPASSSPPQGTSETPASNSPPQG--TSETPGFSSppQVTTATLVSSSPPQVTSETP 429
Cdd:PRK13914   143 VTSTPVAPTQEVKKETTTQQAA---PAAETKTEVKQTTQATTPAPKVaeTKETPVVDQ--NATTHAVKSGDTIWALSVKY 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  430 ASSSPTQVTSETPASSS---PTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDT 506
Cdd:PRK13914   218 GVSVQDIMSWNNLSSSSiyvGQKLAIKQTANTATPKAEVKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKA 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  507 PASSSPPqvtseTPAssspPQVTSDTSASISPPQVISDTPASSSPPQVTSETpaSSSPTNMTSDTPASSSPTNMTSDTPA 586
Cdd:PRK13914   298 PTEAAKP-----APA----PSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTN--TNSNTNTNSNTNANQGSSNNNSNSSA 366


                   ..
gi 1039789995  587 SS 588
Cdd:PRK13914   367 SA 368
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
435-572 3.21e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.15  E-value: 3.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  435 TQVTSETPASSSPTQVTSDT---PASNSPPQGTSDtpgfssPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSS 511
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKPVftqPAAAPQPSAAAA------ASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVP 436

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039789995  512 PPqvtsetPASSSPPQVTSDTSAS---ISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTP 572
Cdd:PRK14971   437 VN------PPSTAPQAVRPAQFKEekkIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTGTQK 494
PRK10856 PRK10856
cytoskeleton protein RodZ;
362-476 3.44e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 44.63  E-value: 3.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  362 DTPSSSSPPQGTSDTP--ASSSPPQGTSETPASNSPPQGTSetpgfSSPPQVTTATlvsssPPQVTSETPASSSPTQVTS 439
Cdd:PRK10856   148 DQSSAELSQNSGQSVPldTSTTTDPATTPAPAAPVDTTPTN-----SQTPAVATAP-----APAVDPQQNAVVAPSQANV 217

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1039789995  440 ETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQV 476
Cdd:PRK10856   218 DTAATPAPAAPATPDGAAPLPTDQAGVSTPAADPNAL 254
PRK08581 PRK08581
amidase domain-containing protein;
353-550 3.45e-04

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 45.16  E-value: 3.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  353 SSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETpgfSSPPQVTTATLVSSSPPQVTSETPASS 432
Cdd:PRK08581   129 LNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPS---SNNTKPSTSNKQPNSPKPTQPNQSNSQ 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  433 SPTQVTSETPASSSPTQVTSDTPASNSPPQgtsdtpgFSSPTQVTTATLVSSSPPQVTSdTPASSSPPQVTSDTPASSSP 512
Cdd:PRK08581   206 PASDDTANQKSSSKDNQSMSDSALDSILDQ-------YSEDAKKTQKDYASQSKKDKTE-TSNTKNPQLPTQDELKHKSK 277

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039789995  513 PQVTSETPAssspPQVTSDTSASISPPQVISDTPASSS 550
Cdd:PRK08581   278 PAQSFENDV----NQSNTRSTSLFETGPSLSNNDDSGS 311
PRK10856 PRK10856
cytoskeleton protein RodZ;
483-564 3.47e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 44.63  E-value: 3.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  483 SSSPPQVTSDTPASSSPPQVTSDTPASSSP--PQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPA 560
Cdd:PRK10856   168 TTTDPATTPAPAAPVDTTPTNSQTPAVATApaPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVSTP 247


                   ....
gi 1039789995  561 SSSP 564
Cdd:PRK10856   248 AADP 251
PPE COG5651
PPE-repeat protein [Function unknown];
267-500 3.56e-04

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 44.50  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  267 QGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPqvtsATSASSSPPQG 346
Cdd:COG5651    155 AAASAAAVALTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSGSGP----IGLNSGPGNTG 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTS 426
Cdd:COG5651    231 FAGTGAAAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGL 310

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039789995  427 ETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPP 500
Cdd:COG5651    311 GAGGAAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAA 384
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 347-604 3.59e-04

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 44.62  E-value: 3.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSpPQGTSDTPASSSPPQGTSETPASNSPPQGtsetpgfSSPPQVTTATLVSSSPPQVts 426
Cdd:COG5068    163 PSDSSEEPSSSASFSVDPNDNN-PMGSFQHNGSPQTNFIPLQNPQTQQYQQH-------SSRKDHPTVPHSNTNNGRP-- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 etPASSSPTQVTSETPASSSPTQVTSDtpaSNSPPQG-TSDTPGFSSPTQVTTATLVsSSPPQVTSDTPASSSPPQVTSD 505
Cdd:COG5068    233 --PAKFMIPELHSSHSTLDLPSDFISD---SGFPNQSsTSIFPLDSAIIQITPPHLP-NNPPQENRHELYSNDSSMVSET 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  506 TPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTP 585
Cdd:COG5068    307 PPPKNLPNGSPNQSPLNNLSRGNPASPNSIIRENNQVEDESFNGRQGSAIWNALISTTQPNSGLHTEASTAPSSTIPADP 386

                          250
                   ....*....|....*....
gi 1039789995  586 ASSSPTNMTSDTPASSSPP 604
Cdd:COG5068    387 LKNAAQTNSGTRNNNFSDN 405
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 455-573 3.60e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.86  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  455 PASNSPPQGTSDTPGfsspTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSdtSA 534
Cdd:PRK07994   366 PEPEVPPQSAAPAAS----AQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATK--AK 439

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1039789995  535 SISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPA 573
Cdd:PRK07994   440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEA 478
PHA03377 PHA03377
EBNA-3C; Provisional
 408-697 3.74e-04

EBNA-3C; Provisional


Pssm-ID: 177614 [Multi-domain]  Cd Length: 1000  Bit Score: 45.04  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  408 PPQVTTATLVSSSPPQVTSE----TPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVS 483
Cdd:PHA03377   399 PVQQRPVMFVSRVPWRKPRTlpwpTPKTHPVKRTLVKTSGRSDEAEQAQSTPERPGPSDQPSVPVEPAHLTPVEHTTVIL 478

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  484 SSPPQVTSDTPASSSPPQV---------------------TSDTPASSSPPQVTSETPASSSppQVTSDTSASISPPQVI 542
Cdd:PHA03377   479 HQPPQSPPTVAIKPAPPPSrrrrgacvvydddiievidveTTEEEESVTQPAKPHRKVQDGF--QRSGRRQKRATPPKVS 556

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  543 -SDT--PASSSP---PQVTSETPASSSPTNMTSDTPASSSPTNMT--SDTPASSSPTNMTSDTPASSSPPWPVITEVTR- 613
Cdd:PHA03377   557 pSDRgpPKASPPvmaPPSTGPRVMATPSTGPRDMAPPSTGPRQQAkcKDGPPASGPHEKQPPSSAPRDMAPSVVRMFLRe 636

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  614 ---PESTIPAGRSLANITSKAQEDSPLGVISTHPQMSFQSSTSQQAldetageRVPTIPDFQAHSEFQKACAILQRLRDF 690
Cdd:PHA03377   637 rllEQSTGPKPKSFWEMRAGRDGSGIQQEPSSRRQPATQSTPPRPS-------WLPSVFVLPSVDAGRAQPSEESHLSSM 709


                   ....*..
gi 1039789995  691 LPTSPTS 697
Cdd:PHA03377   710 SPTQPIS 716
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
366-456 3.92e-04

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 44.84  E-value: 3.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  366 SSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSET-PGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPAS 444
Cdd:PRK11907    19 TASNPKLAQAEEIVTTTPATSTEAEQTTPVESDATEEaDNTETPVAATTAAEAPSSSETAETSDPTSEATDTTTSEARTV 98

                           90
                   ....*....|..
gi 1039789995  445 SSPTqvTSDTPA 456
Cdd:PRK11907    99 TPAA--TETSKP 108
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 471-591 4.06e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 44.56  E-value: 4.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  471 SSPTQVTTATLVSSSPPQVTSDTPA-SSSPPQVTSDTPA-SSSPPQVTSETP--ASSSPPQVTSDTSASISPPQVISDTP 546
Cdd:PTZ00436   220 AAPAKAAAAPAKAAAPPAKAAAAPAkAAAAPAKAAAPPAkAAAPPAKAAAPPakAAAPPAKAAAPPAKAAAPPAKAAAAP 299

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1039789995  547 A-SSSPPQVTSETPA-SSSPTNMTSDTPASSSPTNMTSDTPASSSPT 591
Cdd:PTZ00436   300 AkAAAAPAKAAAAPAkAAAPPAKAAAPPAKAATPPAKAAAPPAKAAA 346
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 429-561 4.77e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.71  E-value: 4.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSEtpaSSSPTQVTSDTPASNSPPQgtsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPA 508
Cdd:PRK14951   366 PAAAAEAAAPAE---KKTPARPEAAAPAAAPVAQ--------AAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAP 434

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  509 SSSPPQVTSETPASSSPPQVTSDTSASI-----SPPQVISDTPASSSPPQVTSETPAS 561
Cdd:PRK14951   435 AAAPAAAPAAVALAPAPPAQAAPETVAIpvrvaPEPAVASAAPAPAAAPAAARLTPTE 492
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 390-530 4.93e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.47  E-value: 4.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  390 PASNSPPQGTSetpgfSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPG 469
Cdd:PRK07994   366 PEPEVPPQSAA-----PAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  470 fSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASS--SPPQVTSETPASSSPPQVTS 530
Cdd:PRK07994   441 -SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRwkATNPVEVKKEPVATPKALKK 502
PHA03132 PHA03132
thymidine kinase; Provisional
 354-473 5.24e-04

thymidine kinase; Provisional


Pssm-ID: 222997 [Multi-domain]  Cd Length: 580  Bit Score: 44.37  E-value: 5.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  354 SSPPQGTLDTPSSSSPPQGTSDTPasSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSS 433
Cdd:PHA03132    65 GVATSTIYTVPRPPRGPEQTLDKP--DSLPASRELPPGPTPVPPGGFRGASSPRLGADSTSPRFLYQVNFPVILAPIGES 142

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1039789995  434 PTqvTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSP 473
Cdd:PHA03132   143 NS--SSEELSEEEEHSRPPPSESLKVKNGGKVYPKGFSKH 180
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
235-487 5.32e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.46  E-value: 5.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  235 ASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSAS 314
Cdd:PRK07003   363 TGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDA 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  315 SSPPQGT-SDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTL-----DTPSSSSPPQGTSDTPASSSPPQGTSE 388
Cdd:PRK07003   443 ADGDAPVpAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFepaprAAAPSAATPAAVPDARAPAAASREDAP 522

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  389 TPASNSPPQGTSETPGFSSPPQVTT---ATL---------VSSSPPQVTSETPASSSPTQVTSETPASSSPTQVtsdtPA 456
Cdd:PRK07003   523 AAAAPPAPEARPPTPAAAAPAARAGgaaAALdvlrnagmrVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQV----PT 598

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1039789995  457 SNSPPQGTSDTPGFSSPTQVTTATLvSSSPP 487
Cdd:PRK07003   599 PRARAATGDAPPNGAARAEQAAESR-GAPPP 628
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
357-501 5.64e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 44.38  E-value: 5.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  357 PQGTLDTPSSSSPPQGTSDT---PASSSPPQgtseTPASNSPPQGTSETPgfSSPPQVTTATLVSSSPPQVtSETPASSS 433
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKPVftqPAAAPQPS----AAAAASPSPSQSSAA--AQPSAPQSATQPAGTPPTV-SVDPPAAV 435

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  434 PTQVTSETPASSSPTQVTSDTPasNSPPQGTSDTPGFSSPTQVTTAtlvsssppQVTSDTPASSSPPQ 501
Cdd:PRK14971   436 PVNPPSTAPQAVRPAQFKEEKK--IPVSKVSSLGPSTLRPIQEKAE--------QATGNIKEAPTGTQ 493
PPE COG5651
PPE-repeat protein [Function unknown];
322-539 5.68e-04

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 44.11  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  322 SDTPASSSPPQVTSATSASSSPPQGTSDTPAS--------SSPPQGTLDTPSSSSPPQGTsdtpASSSPPQGTSETPASN 393
Cdd:COG5651    163 ALTPFTQPPPTITNPGGLLGAQNAGSGNTSSNpgfanlglTGLNQVGIGGLNSGSGPIGL----NSGPGNTGFAGTGAAA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  394 SPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSP 473
Cdd:COG5651    239 GAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGA 318

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  474 TQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPP 539
Cdd:COG5651    319 AGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAA 384
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 204-410 5.84e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  204 IDPASSAPPKATHRMTITSLTGRPQVTSDTLASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQvts 283
Cdd:PRK07764   588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD--- 664

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  284 atSASSSPPQGTSDTPASSSPPQVTsatsasssppqGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDT 363
Cdd:PRK07764   665 --GGDGWPAKAGGAAPAAPPPAPAP-----------AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAP 731

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSS---PPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQ 410
Cdd:PRK07764   732 SPAADdpvPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
Hamartin pfam04388
Hamartin protein; This family includes the hamartin protein which is thought to function as a ...
 205-585 6.00e-04

Hamartin protein; This family includes the hamartin protein which is thought to function as a tumour suppressor. The hamartin protein interacts with the tuberin protein pfam03542. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder and is characterized by the presence of hamartomas in many organs, such as brain, skin, heart, lung, and kidney. It is caused by mutation either TSC1 or TSC2 tumour suppressor gene. TSC1 encodes a protein, hamartin, containing two coiled-coil regions, which have been shown to mediate binding to tuberin. The TSC2 gene codes for tuberin pfam03542. These two proteins function within the same pathway(s) regulating cell cycle, cell growth, adhesion, and vesicular trafficking.


Pssm-ID: 461287 [Multi-domain]  Cd Length: 730  Bit Score: 44.28  E-value: 6.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  205 DPASSAPPKATHRMTITSLTGrpqvTSDTLASSSPPQGTSDTPASSSPPQVTsatsasssppqGTSDTPASS-----SPP 279
Cdd:pfam04388  288 YGSSTSTPSSTPRLQLSSSSG----TSPPYLSPPSIRLKTDSFPLWSPSSVC-----------GMTTPPTSPgmvptTPS 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  280 QVTSATSASSSPPQGTSD---------TPASSSPPQvtsatsasssppqgtsdtpasSSPPqvtsatsasssppqgtsdt 350
Cdd:pfam04388  353 ELSPSSSHLSSRGSSPPEaageatpetTPAKDSPYL---------------------KQPP------------------- 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQgTSETPASNSppqgtseTPGFSSPP-QVTTATLvsSSPPQVTSETP 429
Cdd:pfam04388  393 PLSDSHVHRALPASSQPSSPPRKDGRSQSSFPPL-SKQAPTNPN-------SRGLLEPPgDKSSVTL--SELPDFIKDLA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  430 ASSSPTQVTSETPAS-----SSPTQVTSDTPASNsppqgtsdtPGFSSPTQVTTATLVSSsppQVTSDTPASSSPPQVTS 504
Cdd:pfam04388  463 LSSEDSVEGAEEEAAisqelSEITTEKNETDCSR---------GGLDMPFSRTMESLAGS---QRSRNRIASYCSSTSQS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  505 DTPASSSPPQVTSETPASSSPPQVTSDTSASISPP--QVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTS 582
Cdd:pfam04388  531 DSHGPATTPESKPSALAEDGLRRTKSCSFKQSFTPieQPIESSDDCPTDEQDGENGLETSILTPSPCKIPSRQKVSTQSG 610


                   ...
gi 1039789995  583 DTP 585
Cdd:pfam04388  611 QPL 613
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 356-529 6.23e-04

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 44.15  E-value: 6.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  356 PPQGTLDTPSSSSPPQG----------TSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVT 425
Cdd:PLN03209   382 PPTSPIPTPPSSSPASSksvdavakpaEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGV 461

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  426 SETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTP--ASSSPPQVT 503
Cdd:PLN03209   462 SPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVkvGNSAPPTAL 541

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1039789995  504 SDT---------PASSSPPQVTSETPASSSPPQVT 529
Cdd:PLN03209   542 ADEqhhaqpkprPLSPYTMYEDLKPPTSPTPSPVL 576
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
396-540 6.35e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 44.38  E-value: 6.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  396 PQGTSETPGFSSPPQVTT-ATLVSSSPPQVTSETPASSSPTQvTSETPASSSPTQVtsdTPASNSPPQGTSDTPGfSSPT 474
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKpVFTQPAAAPQPSAAAAASPSPSQ-SSAAAQPSAPQSA---TQPAGTPPTVSVDPPA-AVPV 437

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039789995  475 QVTTATLVSSSPPQVTSDTPASSSppQVTSDTPASSSPPQVTSEtpasssppQVTSDTSASISPPQ 540
Cdd:PRK14971   438 NPPSTAPQAVRPAQFKEEKKIPVS--KVSSLGPSTLRPIQEKAE--------QATGNIKEAPTGTQ 493
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 377-513 6.53e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.32  E-value: 6.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  377 PASSSPPQGTSETPASNSPPQGTsetPGFSSPPQVTTATLVSSSPPQVTSET---PASSSPTQVTSETPASSSPTQVTSD 453
Cdd:PRK14951   366 PAAAAEAAAPAEKKTPARPEAAA---PAAAPVAQAAAAPAPAAAPAAAASAPaapPAAAPPAPVAAPAAAAPAAAPAAAP 442

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  454 TPASNSPPQGTSDTPGFSSPtqvttatlvsssPPQVTSDTPASSSPPQVTSDTPASSSPP 513
Cdd:PRK14951   443 AAVALAPAPPAQAAPETVAI------------PVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK10856 PRK10856
cytoskeleton protein RodZ;
431-525 6.56e-04

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 43.48  E-value: 6.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  431 SSSPTQVTSETPASSSPTQVTSDTPASNSPPQGtsdtpgfSSPTQVTTATlvssSPPQVTSDTPASSSPPQVTSDTPASS 510
Cdd:PRK10856   168 TTTDPATTPAPAAPVDTTPTNSQTPAVATAPAP-------AVDPQQNAVV----APSQANVDTAATPAPAAPATPDGAAP 236

                           90
                   ....*....|....*
gi 1039789995  511 SPPQVTSETPASSSP 525
Cdd:PRK10856   237 LPTDQAGVSTPAADP 251
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
378-468 6.58e-04

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 44.46  E-value: 6.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  378 ASSSPPQGTSETPASNSPPQGTSETPgfSSPPQVTTAT---LVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDT 454
Cdd:PRK11907    18 LTASNPKLAQAEEIVTTTPATSTEAE--QTTPVESDATeeaDNTETPVAATTAAEAPSSSETAETSDPTSEATDTTTSEA 95

                           90
                   ....*....|....
gi 1039789995  455 PAsnSPPQGTSDTP 468
Cdd:PRK11907    96 RT--VTPAATETSK 107
PHA02732 PHA02732
hypothetical protein; Provisional
 355-609 7.20e-04

hypothetical protein; Provisional


Pssm-ID: 165099 [Multi-domain]  Cd Length: 1467  Bit Score: 44.36  E-value: 7.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  355 SPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSP-PQGTSETPGFS-SPPQVTTATLVSSSPPQ----VTSET 428
Cdd:PHA02732  1074 SPSYIFLNSWASSYVAPGFLGSPYALPYFMNQTSALVGNTAlPKGLNVFSGYMfGAGTVASAFLYMNSTPQspvlALLLA 1153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSETPASSSPTQVTSDTP------ASNSPPQG----TSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSS 498
Cdd:PHA02732  1154 PYISYKFNALSLGFSITADAAIFSLFGipapqlLSSYIPTGsvlyQDPIFTYIPPGIIGMSGTNTFTFKAAQLQLSAASS 1233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  499 PPQVTSDTPASSSPPQVTSETpASSSPP--QVTSDTSASISPPQVISdtPASSSPP--QVTSETPASSSPTNMTS-DTPA 573
Cdd:PHA02732  1234 PPAATTPTPPPSSSSSSSAQS-ISTSPGqiQIVLNGSTTIHINFLFF--PALSTPKigQILAMPIVNSSGAFISLyVNSA 1310

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1039789995  574 SSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVIT 609
Cdd:PHA02732  1311 ISANFNVTIEYVFSNGTVIKRFTDEPGQIFPLPLIN 1346
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 430-603 7.29e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.22  E-value: 7.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  430 ASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPgfssptQVTTAtlVSSSPPQVT-SDTPasSSPPQVTSDTPA 508
Cdd:TIGR00927   55 SSQQPIKLASRDLSNDEMMMVSSDPPKSSSEMEGEMLAP------QATVG--RDEATPSIAmENTP--SPPRRTAKITPT 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  509 SSSppqvTSETPASSSPPQVTSDTSAsiSPPQVISDTPASSSPPQVTSETPA------SSSPTNMTSDTPA-SSSPTNMT 581
Cdd:TIGR00927  125 TPK----NNYSPTAAGTERVKEDTPA--TPSRALNHYISTSGRQRVKSYTPKprgevkSSSPTQTREKVRKyTPSPLGRM 198

                          170       180
                   ....*....|....*....|..
gi 1039789995  582 SDTPASSspTNMTSDTPASSSP 603
Cdd:TIGR00927  199 VNSYAPS--TFMTMPRSHGITP 218
SP2_N cd22540
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins ...
 351-604 7.31e-04

N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP2 contains the least conserved DNA-binding domain within the SP subfamily of proteins, and its DNA sequence specificity differs from the other SP proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate, or in some cases, repress expression from different promoters. The transcription factor SP2 serves as a paradigm for indirect genomic binding. It does not require its DNA-binding domain for genomic DNA binding and occupies target promoters independently of whether they contain a cognate DNA-binding motif. SP2 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP2.


Pssm-ID: 411776 [Multi-domain]  Cd Length: 511  Bit Score: 43.76  E-value: 7.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  351 PASSSPPQGTLDTPSSSS------PPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSS---- 420
Cdd:cd22540     66 PLPLGPGKNSIGFLSAKGniiqlqGSQLSSSAPGGQQVFAIQNPTMIIKGSQTRSSTNQQYQISPQIQAAGQINNSgqiq 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  421 -----------PPQVTSETPASSSPTQV---------TSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTAT 480
Cdd:cd22540    146 iipgtnqaiitPVQVLQQPQQAHKPVPIkpaplqtsnTNSASLQVPGNVIKLQSGGNVALTLPVNNLVGTQDGATQLQLA 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  481 LVSSSPPQVTSDTPASSSPPQVTS--------------------------DTPASSSPPQV--------TSETPASSSPP 526
Cdd:cd22540    226 AAPSKPSKKIRKKSAQAAQPAVTVaeqvetvliettadniiqagnnllivQSPGTGQPAVLqqvqvlqpKQEQQVVQIPQ 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  527 ------QVTSDTSASI--SPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTP 598
Cdd:cd22540    306 qalrvvQAASATLPTVpqKPLQNIQIQNSEPTPTQVYIKTPSGEVQTVLLQEAPAATATPSSSTSTVQQQVTANNGTGTS 385


                   ....*.
gi 1039789995  599 ASSSPP 604
Cdd:cd22540    386 KPNYNV 391
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
460-636 7.34e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.07  E-value: 7.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  460 PPQGTSDTPGFSSPTQVTTAtlVSSSPPQVTSDTPASSSPPQvtsdTPASSSPPQVTSETPASSSPPQVTSDTSASISPP 539
Cdd:PRK07003   360 PAVTGGGAPGGGVPARVAGA--VPAPGARAAAAVGASAVPAV----TAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPP 433

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  540 Q---VISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTnmTSDTPASSSPTNMTSDtPASSSPPWPVITEVTRPES 616
Cdd:PRK07003   434 AtadRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSG--SASAPASDAPPDAAFE-PAPRAAAPSAATPAAVPDA 510

                          170       180
                   ....*....|....*....|
gi 1039789995  617 TIPAGRSLANITSKAQEDSP 636
Cdd:PRK07003   511 RAPAAASREDAPAAAAPPAP 530
PRK13042 PRK13042
superantigen-like protein SSL4; Reviewed;
428-518 7.41e-04

superantigen-like protein SSL4; Reviewed;


Pssm-ID: 183854 [Multi-domain]  Cd Length: 291  Bit Score: 43.08  E-value: 7.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPTQVTSDTPASNSPpqgtsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTP 507
Cdd:PRK13042    18 TGVITTTTQAANATTPSSTKVEAPQSTPPSTKV----------EAPQSKPNATTPPSTKVEAPQQTPNATTPSSTKVETP 87

                           90
                   ....*....|.
gi 1039789995  508 ASSSPPQVTSE 518
Cdd:PRK13042    88 QSPTTKQVPTE 98
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 364-499 7.87e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 43.90  E-value: 7.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPqvTSETPASSSPTQVTSETPa 443
Cdd:PRK14959   367 PVESLRPSGGGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPA--PSAAPSPRVPWDDAPPAP- 443

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  444 sssptqvtsdtPASNSPPQGTSDTPGFSSPT--QVTTATLVSSSPPQVTSDTPASSSP 499
Cdd:PRK14959   444 -----------PRSGIPPRPAPRMPEASPVPgaPDSVASASDAPPTLGDPSDTAEHTP 490
PHA03193 PHA03193
tegument protein VP11/12; Provisional
 368-511 8.13e-04

tegument protein VP11/12; Provisional


Pssm-ID: 177555  Cd Length: 594  Bit Score: 43.94  E-value: 8.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  368 SPPQGTSDTPASSSPpqgTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPAS------SSPTQVTSET 441
Cdd:PHA03193   441 SPFQRKRAMPEDGGE---IHEALANNGQAIFPECFSGDLPPIAQALLSADELPNDTTASTSNEMkgdaecPAAQDAAAIL 517

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  442 PASSsptQVTSDTPASNSPPQGTSDTpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSS 511
Cdd:PHA03193   518 PASF---QIENGGAADGSGLAIPAAM---CDATAVESPSTVAETPPERLLAAESGPRCKATAKHKGGSSK 581
KLF12_N cd21441
N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as ...
 555-603 8.14e-04

N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as Krueppel-like transcription factor 12, KLF12) regulates, by transcriptionally repressing Nur77 expression, endometrial decidualization, which is a prerequisite for successful implantation and the establishment of pregnancy. It is involved in the maturation processes of kidney collecting ducts after birth, and is able to increase the promoter activity of the UT-A1 urea transporter promoter by binding to the CACCC motif. KLF12 has also been found to promote colorectal cancer growth is also involved in the invasion and apoptosis of basal-like breast carcinoma. KLF12 belongs to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Although these factors bind to similar elements in vitro, they have distinct activities in vivo depending on their expression profile and the sequence of the N-terminal activation/repression domain, which differ between members. KLF12 contains an N-terminal domain that is related to the N-terminal repression domain of KLF8.


Pssm-ID: 410608 [Multi-domain]  Cd Length: 197  Bit Score: 42.30  E-value: 8.14e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1039789995  555 TSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSP 603
Cdd:cd21441     65 TSPTAVSSSPVSMTASASPSSSSSSSSSSSRPASSPTVITSVSSASSVP 113
PHA03255 PHA03255
BDLF3; Provisional
 490-670 8.16e-04

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 42.58  E-value: 8.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  490 TSDTPASSSPPQVTSDTPasssppqVTSETPASSSPPQVTSDTSASISPPqvISDTPASSSPPQVTSETPASSSPTNMTS 569
Cdd:PHA03255    25 TSSGSSTASAGNVTGTTA-------VTTPSPSASGPSTNQSTTLTTTSAP--ITTTAILSTNTTTVTSTGTTVTPVPTTS 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  570 DTPASSSPTNMTSDTPASSSptnmtsdTPASSSPPwPVITEVTRPESTIPAGRSLANITSKAQEdsplgvisthpqmsfQ 649
Cdd:PHA03255    96 NASTINVTTKVTAQNITATE-------AGTGTSTG-VTSNVTTRSSSTTSATTRITNATTLAPT---------------L 152

                          170       180
                   ....*....|....*....|.
gi 1039789995  650 SSTSQQALDETAGErVPTIPD 670
Cdd:PHA03255   153 SSKGTSNATKTTAE-LPTVPD 172
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
383-514 8.71e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 43.61  E-value: 8.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  383 PQGTSETPASNSPPQGTSetPGFS---SPPQVTTATLVSSSPPQvTSETPASSSPTQVtseTPASSSPTQVTSDTP-ASN 458
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIK--PVFTqpaAAPQPSAAAAASPSPSQ-SSAAAQPSAPQSA---TQPAGTPPTVSVDPPaAVP 436

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  459 SPPQGT---SDTPGFSSPTQVTTATLVSSSPPQVTSdtPASSSPPQVTSDTPASSSPPQ 514
Cdd:PRK14971   437 VNPPSTapqAVRPAQFKEEKKIPVSKVSSLGPSTLR--PIQEKAEQATGNIKEAPTGTQ 493
DUF612 pfam04747
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ...
 270-575 9.19e-04

Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.


Pssm-ID: 282585 [Multi-domain]  Cd Length: 511  Bit Score: 43.51  E-value: 9.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  270 SDTPASSSPpQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSppqgTSDTPASSSPPQvtSATSASSSPPQGTSD 349
Cdd:pfam04747  198 TNTPAEPAE-QVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKV----VTEEPHQQAAPQ--EKKNKKNKRKSESEN 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  350 TPASS-SPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQgtSETPGFSSPPQVTTATLVSSSPPQVTSET 428
Cdd:pfam04747  271 VPAASeTPVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPK--SKKPTADDNMDFLDFVTAKEEPKDEPAET 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASssPTQVTSETPASSSPTQVTSdTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVT----SDTPASSSPPQVTS 504
Cdd:pfam04747  349 PAA--PVEEVVENVVENVVEKSTT-PPATENKKKNKKDKKKSESEKVTEQPVESAPAPPQVEqvveTTPPASENKKKNKK 425

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  505 DTPASSSPPQVtsETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASS 575
Cdd:pfam04747  426 DKKKSESEKAV--EEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEETAAAA 494
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
 350-558 9.58e-04

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 43.66  E-value: 9.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  350 TPASSSPPQGTLDTPSssspPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFS--SPPQVTTATLVSSSPPQVTSE 427
Cdd:pfam09786  129 PPKSKSSPQSPSPVLV----PLHQSVSPSSSESRKGGDKSPAGSGKKLRSFSTSSKSpaSPSVYLRGSPVPLNSSPLPSD 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  428 TPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSpPQVTSDTP 507
Cdd:pfam09786  205 RNYENSVQSSPEIDSAVSTPWSRKRATIGKEIRTEKMLERFLAEVDEKITESAFGKASPSNVSGSANRSGS-TRSTPLRS 283

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  508 ASSSPPQVTSETPASSSPpqvtSDTSASISPPQVISDTPASSSPPQVTSET 558
Cdd:pfam09786  284 VRMSPGSQKFTTPPKKGE----GDLPSPMSMEENIEAFENLGIYPQIEQWR 330
PHA03379 PHA03379
EBNA-3A; Provisional
 211-606 9.73e-04

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 43.89  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  211 PP---KATHRMTITSLTGRPQVTSDTLASssPPQGTSDTPassSPPQVTSATSASSSPPQGTSDTPASS-SPPQVTSATS 286
Cdd:PHA03379   379 PPiflRRLHRLLLMRAGKLTERAREALEK--ASEPTYGTP---RPPVEKPRPEVPQSLETATSHGSAQVpEPPPVHDLEP 453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  287 ASSSPPQGTSDTPASSSPPqvtsatsasssppqgtsdtpassSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSS 366
Cdd:PHA03379   454 GPLHDQHSMAPCPVAQLPP-----------------------GPLQDLEPGDQLPGVVQDGRPACAPVPAPAGPIVRPWE 510

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  367 SSPPQGTSDTPASSSP----------PQGTSETPASNSPP----QGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASS 432
Cdd:PHA03379   511 ASLSQVPGVAFAPVMPqpmpvepvpvPTVALERPVCPAPPliamQGPGETSGIVRVRERWRPAPWTPNPPRSPSQMSVRD 590

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  433 SPTQVTSET-----PASSSPTQVTSDTPAS-----NSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTS---DTPASSSP 499
Cdd:PHA03379   591 RLARLRAEAqpyqaSVEVQPPQLTQVSPQQpmeypLEPEQQMFPGSPFSQVADVMRAGGVPAMQPQYFDlplQQPISQGA 670

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  500 PQVTSDTPASSSPPqVTSETPASSSPPqVTSDTSASISPPQVISDTPAssSPPQVtseTPASSSPTNMTSDTPASSSPTN 579
Cdd:PHA03379   671 PLAPLRASMGPVPP-VPATQPQYFDIP-LTEPINQGASAAHFLPQQPM--EGPLV---PERWMFQGATLSQSVRPGVAQS 743

                          410       420
                   ....*....|....*....|....*..
gi 1039789995  580 MTSDTPASSSPTNMTSDTPASSSPPWP 606
Cdd:PHA03379   744 QYFDLPLTQPINHGAPAAHFLHQPPME 770
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 434-560 9.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 43.70  E-value: 9.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  434 PTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTS----DTPAS 509
Cdd:PRK07994   361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRaqgaTKAKK 440

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  510 SSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQ-------VTSETPA 560
Cdd:PRK07994   441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATnpvevkkEPVATPK 498
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 442-578 9.83e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.55  E-value: 9.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  442 PASSSPTQVTSDTPASNSPPQGTsdtPGFSSPTQVTTATLVSSSPPQVTSdtpASSSPPqvtsdTPASSSPPQVTSETPA 521
Cdd:PRK14951   366 PAAAAEAAAPAEKKTPARPEAAA---PAAAPVAQAAAAPAPAAAPAAAAS---APAAPP-----AAAPPAPVAAPAAAAP 434

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  522 SSSPPQVTSdtSASISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPT 578
Cdd:PRK14951   435 AAAPAAAPA--AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLT 489
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 487-620 1.01e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 43.70  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  487 PQVTSDTPASssPPQVTSDTPASssppQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTN 566
Cdd:PRK07994   361 PAAPLPEPEV--PPQSAAPAASA----QATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQG 434

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  567 mtSDTPASSSPTNMTSDTPASSSPTNMTSDTP-ASSSPPWPVITEVTRPESTIPA 620
Cdd:PRK07994   435 --ATKAKKSEPAAASRARPVNSALERLASVRPaPSALEKAPAKKEAYRWKATNPV 487
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 427-578 1.03e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.01  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 ETPASSSPTQVTSETPASSSPTQVTSdtpASNSPPQGTSDTPGFSS--PTQVTTATLVSSSPPQVTSDTPA-SSSPPQVT 503
Cdd:PTZ00436   191 EDAAAAAAAKQKAAAKKAAAPSGKKS---AKAAAPAKAAAAPAKAAapPAKAAAAPAKAAAAPAKAAAPPAkAAAPPAKA 267

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  504 SDTPA-SSSPPQVTSETP--ASSSPPQVTSDTSASISPPQVISDTPA-SSSPPQVTSETPASSSPTNMTSDTPASSSPT 578
Cdd:PTZ00436   268 AAPPAkAAAPPAKAAAPPakAAAPPAKAAAAPAKAAAAPAKAAAAPAkAAAPPAKAAAPPAKAATPPAKAAAPPAKAAA 346
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 436-638 1.03e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 43.38  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  436 QVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQvtSDTPASsspPQVTSDTPASSSPPQV 515
Cdd:PLN03209   304 EVIAETTAPLTPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPI--EEEPPQ---PKAVVPRPLSPYTAYE 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  516 TSETPASSSPPQVTSDTSAS-----ISPPQVISDTPASSSPPQV------TSET-----------------PASSSPTNM 567
Cdd:PLN03209   379 DLKPPTSPIPTPPSSSPASSksvdaVAKPAEPDVVPSPGSASNVpevepaQVEAkktrplspyaryedlkpPTSPSPTAP 458

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  568 TSDTPASSSPT--NMTSDTPASSSPTNMTSDTPASSSP--PWPVITEVTRPESTIPAGRSLANITSKAQEDSPLG 638
Cdd:PLN03209   459 TGVSPSVSSTSsvPAVPDTAPATAATDAAAPPPANMRPlsPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVG 533
motB PRK12799
flagellar motor protein MotB; Reviewed
 425-556 1.06e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 43.17  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVts 504
Cdd:PRK12799   296 HGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQS----ATTTQASAVALSSAGVLPSDVTLPGTVALPAA-- 369

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  505 dTPASSSPPQVTSETPASSSPPQVTSDTSasiSPPQVISDTPASSSPPQVTS 556
Cdd:PRK12799   370 -EPVNMQPQPMSTTETQQSSTGNITSTAN---GPTTSLPAAPASNIPVSPTS 417
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 347-551 1.15e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.52  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQgTLDTPSSSSPPQgtsdTPASSSPPQGTsETPASNSPPQgtSETPGFSspPQVTTATLVSSSppqvts 426
Cdd:PTZ00449   617 LLDIPKSPKRPE-SPKSPKRPPPPQ----RPSSPERPEGP-KIIKSPKPPK--SPKPPFD--PKFKEKFYDDYL------ 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 eTPASSSPTQVTSETPASSSPTQVTSDTPASNSPPqgtSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASS---SPPQVT 503
Cdd:PTZ00449   681 -DAAAKSKETKTTVVLDESFESILKETLPETPGTP---FTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDIeffTPPEEE 756

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039789995  504 S----DTPASSSPPQVTSETPASsspPQVTSDTSASISP------PQVISDTPASSSP 551
Cdd:PTZ00449   757 RtffhETPADTPLPDILAEEFKE---EDIHAETGEPDEAmkrpdsPSEHEDKPPGDHP 811
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
443-552 1.30e-03

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 43.30  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  443 ASSSPTQVTSDTPASNSPPqgtsdtpgfSSPTQVTTATLVSSSppqVTSDTPASSSPPQVTSDTPASSSPpqvtsETPAS 522
Cdd:PRK11907    18 LTASNPKLAQAEEIVTTTP---------ATSTEAEQTTPVESD---ATEEADNTETPVAATTAAEAPSSS-----ETAET 80

                           90       100       110
                   ....*....|....*....|....*....|
gi 1039789995  523 SSPPQVTSDTSASISPPQVISDTpaSSSPP 552
Cdd:PRK11907    81 SDPTSEATDTTTSEARTVTPAAT--ETSKP 108
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 404-526 1.39e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  404 GFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVS 483
Cdd:PRK14951   369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALA 448

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1039789995  484 SSPPQVTSDTPAsSSPPQVTSDTPASSSPPQVTSETPASSSPP 526
Cdd:PRK14951   449 PAPPAQAAPETV-AIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 430-554 1.43e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.63  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  430 ASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPgfssPTQVTTATLVSSSPPQVTSDTPA-SSSPPQVTSDTPA 508
Cdd:PTZ00436   225 AAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAP----PAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAAPA 300

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1039789995  509 -SSSPPQVTSETPA--SSSPPQVTSDTSASISPPQVISDTPASSSPPQV 554
Cdd:PTZ00436   301 kAAAAPAKAAAAPAkaAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAPV 349
KLF12_N cd21441
N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as ...
 542-603 1.66e-03

N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as Krueppel-like transcription factor 12, KLF12) regulates, by transcriptionally repressing Nur77 expression, endometrial decidualization, which is a prerequisite for successful implantation and the establishment of pregnancy. It is involved in the maturation processes of kidney collecting ducts after birth, and is able to increase the promoter activity of the UT-A1 urea transporter promoter by binding to the CACCC motif. KLF12 has also been found to promote colorectal cancer growth is also involved in the invasion and apoptosis of basal-like breast carcinoma. KLF12 belongs to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Although these factors bind to similar elements in vitro, they have distinct activities in vivo depending on their expression profile and the sequence of the N-terminal activation/repression domain, which differ between members. KLF12 contains an N-terminal domain that is related to the N-terminal repression domain of KLF8.


Pssm-ID: 410608 [Multi-domain]  Cd Length: 197  Bit Score: 41.15  E-value: 1.66e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  542 ISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSP 603
Cdd:cd21441     65 TSPTAVSSSPVSMTASASPSSSSSSSSSSSRPASSPTVITSVSSASSVPTVLTPGPLVASAS 126
PRK12495 PRK12495
hypothetical protein; Provisional
 450-563 1.68e-03

hypothetical protein; Provisional


Pssm-ID: 183558 [Multi-domain]  Cd Length: 226  Bit Score: 41.78  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  450 VTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQV-TSDTPASSSPPQVTSETPASSSPPQV 528
Cdd:PRK12495    68 VTEDGAAGDDAGDGAEATAPSDAGSQASPDDDAQPAAEAEAADQSAPPEASSTsATDEAATDPPATAAARDGPTPDPTAQ 147

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1039789995  529 TSDTSASISP---PQVISDTPASSSPPQVTSETPASSS 563
Cdd:PRK12495   148 PATPDERRSPrqrPPVSGEPPTPSTPDAHVAGTLQAAR 185
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 414-552 1.68e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 42.93  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  414 ATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTsdtPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSdt 493
Cdd:PRK07994   363 APLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVP---PPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATK-- 437

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  494 PASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSAS-ISPPQVISDTPASSSPP 552
Cdd:PRK07994   438 AKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYrWKATNPVEVKKEPVATP 497
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
507-660 1.69e-03

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 42.73  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  507 PASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPA----SSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTS 582
Cdd:pfam05539  169 KTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATAnqrlSSTEPVGTQGTTTSSNPEPQTEPPPSQRGPSGSPQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  583 DTPASSSP-TNMTSD----TPASSSPPWPVITEVTRPESTIPAgrSLANITSKAQEDSPLGVISTHPQMSFQSSTSQQAL 657
Cdd:pfam05539  249 HPPSTTSQdQSTTGDgqehTQRRKTPPATSNRRSPHSTATPPP--TTKRQETGRPTPRPTATTQSGSSPPHSSPPGVQAN 326


                   ...
gi 1039789995  658 DET 660
Cdd:pfam05539  327 PTT 329
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 208-572 1.73e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.06  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  208 SSAPPKATHRMTITSLTGRPQVTSDtlaSSSPPQGTSDTPassSPPQVTSATSASSSPpqgTSDTPASSSPPQVtsatsa 287
Cdd:TIGR00927   76 SSDPPKSSSEMEGEMLAPQATVGRD---EATPSIAMENTP---SPPRRTAKITPTTPK---NNYSPTAAGTERV------ 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  288 sssppqgTSDTPASssPPQVTSATSASSSPPQGTSDTPA------SSSPPQVTSatsasssppQGTSDTPASSSPPQGTL 361
Cdd:TIGR00927  141 -------KEDTPAT--PSRALNHYISTSGRQRVKSYTPKprgevkSSSPTQTRE---------KVRKYTPSPLGRMVNSY 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  362 DTPSSSSPPQGTSDTPASSsppQGTSETPASNS--PPQGTSETPGFSSPpqVTTATLVSSSPPQVTS--ETPASSSPTQV 437
Cdd:TIGR00927  203 APSTFMTMPRSHGITPRTT---VKDSEITATYKmlETNPSKRTAGKTTP--TPLKGMTDNTPTFLTRevETDLLTSPRSV 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  438 TsETPASSSPTQVTSDTPAS-------NSP--PQGT--SDTPGfSSPTQVTTATLVSSSPPQVTSDTPA-SSSPPQVTSD 505
Cdd:TIGR00927  278 V-EKNTLTTPRRVESNSSTNhwglvgkNNLttPQGTvlEHTPA-TSEGQVTISIMTGSSPAETKASTAAwKIRNPLSRTS 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  506 TPA-------------SSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPaSSSPTNMTSDTP 572
Cdd:TIGR00927  356 APAvriasatfrglekNPSTAPSTPATPRVRAVLTTQVHHCVVVKPAPAVPTTPSPSLTTALFPEAP-SPSPSALPPGQP 434
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 485-609 1.74e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  485 SPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSAsiSPPQVISDTPASSSPPQVTSETPASSSP 564
Cdd:PRK14951   372 AAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAA--PPAPVAAPAAAAPAAAPAAAPAAVALAP 449

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1039789995  565 TNMTSDTPASSSPTNMTSDTPASSSPtnmtSDTPASSSPPWPVIT 609
Cdd:PRK14951   450 APPAQAAPETVAIPVRVAPEPAVASA----APAPAAAPAAARLTP 490
motB PRK12799
flagellar motor protein MotB; Reviewed
 399-530 1.81e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 42.40  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  399 TSETPGFSSPPqvTTATLVSSSPPQVTSETPASssptqVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTT 478
Cdd:PRK12799   296 HGTVPVAAVTP--SSAVTQSSAITPSSAAIPSP-----AVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPA 368

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  479 ATLVSSSPPQVTSDTPASSSppqVTSDTPASSSPPQVTSETPASSSPPQVTS 530
Cdd:PRK12799   369 AEPVNMQPQPMSTTETQQSS---TGNITSTANGPTTSLPAAPASNIPVSPTS 417
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 346-460 2.11e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 42.36  E-value: 2.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  346 GTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGF---SSPPQVTTATLVSSSPP 422
Cdd:PRK14959   375 GGGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVpwdDAPPAPPRSGIPPRPAP 454

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1039789995  423 QVTSETPASSSPTQVTSEtpASSSPTQVTSDTPASNSP 460
Cdd:PRK14959   455 RMPEASPVPGAPDSVASA--SDAPPTLGDPSDTAEHTP 490
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
460-647 2.16e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 2.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  460 PPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASI--- 536
Cdd:PRK12323   365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASArgp 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  537 ----SPPQVISDTPASSSPPQVTS-ETPASSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWP--VIT 609
Cdd:PRK12323   445 ggapAPAPAPAAAPAAAARPAAAGpRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAgwVAE 524

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039789995  610 EVTRPESTIPAGRSLANITSKAQEDSPLGVISTHPQMS 647
Cdd:PRK12323   525 SIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA 562
SAP130_C pfam16014
Histone deacetylase complex subunit SAP130 C-terminus;
415-590 2.24e-03

Histone deacetylase complex subunit SAP130 C-terminus;


Pssm-ID: 464973 [Multi-domain]  Cd Length: 371  Bit Score: 42.23  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  415 TLVSSSPPQVTSETPA-----SSSPTQVTSETPASSSPTQVT---SDTPASNSPPqgTSDTPGFSSPTQVTTATlVSSSP 486
Cdd:pfam16014    1 ALGSSPRPSILRKKPAtegakPKPDIHVAVAPPVTVAVEALPgqnSEQQTASASP--PSQHPAQAIPTILAPAA-PPSQP 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  487 PQVTSDTPASS--SPPQVTSDTPASSSPPQvtsetPASSSPPQ-VTSDTSASISPPQVISDTPASSSPPQVTSETPASSs 563
Cdd:pfam16014   78 SVVLSTLPAAMavTPPIPASMANVVAPPTQ-----PAASSTAAcAVSSVLPEIKIKQEAEPMDTSQSVPPLTPTSISPA- 151

                          170       180
                   ....*....|....*....|....*..
gi 1039789995  564 ptnMTSDTPASSSPtnmTSDTPASSSP 590
Cdd:pfam16014  152 ---LTSLANNLSVP---AGDLLPGASP 172
PRK10856 PRK10856
cytoskeleton protein RodZ;
419-512 2.25e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 41.94  E-value: 2.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  419 SSPPQVTSETPASSSPTQVtseTPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSS 498
Cdd:PRK10856   161 SVPLDTSTTTDPATTPAPA---APVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPL 237

                           90
                   ....*....|....
gi 1039789995  499 PPQVTSDTPASSSP 512
Cdd:PRK10856   238 PTDQAGVSTPAADP 251
PLN03131 PLN03131
hypothetical protein; Provisional
 378-609 2.48e-03

hypothetical protein; Provisional


Pssm-ID: 178677 [Multi-domain]  Cd Length: 705  Bit Score: 42.46  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  378 ASSSPPQGTSETPA-SNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTS---ETPASSSPTqvtSD 453
Cdd:PLN03131   356 APMAPPIDLFQLPAtSPAPPVDLFEIPPLDPAPAINAYQPPQTSLPSSIDLFGGITQQQSINSldeKSPELSIPK---NE 432

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  454 TPASNSPPQGTSDTPGFS--SPTQVTTATLVSSSPPQVTSDTPASSSPP-QVTSDTPASSSPPQVTSETPASSSPPQVTS 530
Cdd:PLN03131   433 GWATFDGIQPIASTPGNEnlTPFSIGPSMAGSANFDQVPSLDKGMQWPPfQNSSDEESASGPAPWLGDLHNVEAPDNTSA 512

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  531 DTSASISPPQVISDTPASSSPPQVTSETPASSSPT-NMTSDTPASSSPT---------NMTSDTPASSSPTNMTSDtPAS 600
Cdd:PLN03131   513 QNWNAFEFDDSVAGIPLEGIKQSSEPQTAANMPPTaDQLIGCKALEDFNkdgikrtapHGQGELPGLDEPSDILAE-PSY 591


                   ....*....
gi 1039789995  601 SSPPWPVIT 609
Cdd:PLN03131   592 TPPAHPIME 600
PRK10856 PRK10856
cytoskeleton protein RodZ;
418-499 2.66e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 41.55  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  418 SSSPPQVTSETPA--SSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPA 495
Cdd:PRK10856   168 TTTDPATTPAPAApvDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGAAPLPTDQAGVSTP 247


                   ....
gi 1039789995  496 SSSP 499
Cdd:PRK10856   248 AADP 251
DUF3583 pfam12126
Protein of unknown function (DUF3583); This domain is found in eukaryotes, and is typically ...
 388-571 2.72e-03

Protein of unknown function (DUF3583); This domain is found in eukaryotes, and is typically between 302 and 338 amino acids in length. It is found in association with pfam00097 and pfam00643. Most members are promyelocytic leukemia proteins, and this family lies towards the C-terminus.


Pssm-ID: 432347 [Multi-domain]  Cd Length: 329  Bit Score: 41.72  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  388 ETPASnspPQGTSETPGF-----------SSPPQVTTATLVSSSPPQvTSETPASSSptqvTSETPASSSPTQVTSDTPA 456
Cdd:pfam12126  123 EEPQN---LQAAVRTDGFdefkvrlqdlvSCITQGTDAAVSRRASPE-AASTPRDPS----DVDLPEEVQRVQAQALGLA 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  457 SNSPPQGTSDTPGfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSET---PASSSPPQVTSDTS 533
Cdd:pfam12126  195 ETQPVAVVQSVPG-AHPVPVYAFSIKDPSYREEVSNTVTPQKRKSCQTECPRKVIKMESEEEKearLARSSPEQPRPSTS 273

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1039789995  534 ASISPPQVisDTPASSSPPQVTSETPASSSpTNMTSDT 571
Cdd:pfam12126  274 KAVSPPHL--DGPPSPESPIVGKEVLLPNS-NHVTSDP 308
PHA03193 PHA03193
tegument protein VP11/12; Provisional
 347-476 2.97e-03

tegument protein VP11/12; Provisional


Pssm-ID: 177555  Cd Length: 594  Bit Score: 42.01  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSPPqgtsdtpASSSPPQGTSETPASNSPPQGTsETPGFSSPPQVTTATLVSSSppQVTS 426
Cdd:PHA03193   456 IHEALANNGQAIFPECFSGDLPPI-------AQALLSADELPNDTTASTSNEM-KGDAECPAAQDAAAILPASF--QIEN 525

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039789995  427 ETPASSSPTQVTSetpASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQV 476
Cdd:PHA03193   526 GGAADGSGLAIPA---AMCDATAVESPSTVAETPPERLLAAESGPRCKAT 572
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 350-435 3.07e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 41.86  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  350 TPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASnspPQGTSETPGFSSPPqvttatlvsssPPQVTSETP 429
Cdd:PHA03291   204 VPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPSTTIAAPQ---AGTTPEAEGTPAPP-----------TPGGGEAPP 269


                   ....*.
gi 1039789995  430 ASSSPT 435
Cdd:PHA03291   270 ANATPA 275
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 345-444 3.12e-03

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 42.00  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPASSSP---------PQGTLDTPSSSSPPQ---GTSDTPASSSPPQGTSETPASNSPPQGTSE--TPGFSSP-- 408
Cdd:PLN02217   545 QGDAWIPGKGVPyipglfagnPGSTNSTPTGSAASSnttFSSDSPSTVVAPSTSPPAGHLGSPPATPSKivSPSTSPPas 624

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1039789995  409 ----PQVTTATLVSSSPPQVTSETPASSSPTQVTSETPAS 444
Cdd:PLN02217   625 hlgsPSTTPSSPESSIKVASTETASPESSIKVASTESSVS 664
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
325-532 3.36e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 41.87  E-value: 3.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  325 PASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPG 404
Cdd:PRK14948   364 FISEIANASAPANPTPAPNPSPPPAPIQPSAPKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPANAANAPPSLNLEE 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  405 -----FSSPPQVTT-------ATLVSSSPPQVT------------SETP--------ASSSPTQVTSETPASSSPTQVTS 452
Cdd:PRK14948   444 lwqqiLAKLELPSTrmllsqqAELVSLDSNRAViavspnwlgmvqSRKPlleqafakVLGRSIKLNLESQSGSASNTAKT 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  453 DTPASNSPPQGTSdTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPqvtsdtPASSSPPQVTSETPASSSPPQVTSDT 532
Cdd:PRK14948   524 PPPPQKSPPPPAP-TPPLPQPTATAPPPTPPPPPPTATQASSNAPAQI------PADSSPPPPIPEEPTPSPTKDSSPEE 596
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 239-599 3.46e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.98  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  239 PPQGTSDTPASSSPPQvtsatsasssppqGtsdtPASSSPPQVTSATSASSSPPQGTSDtpaSSSPPQVTSATSASSSPP 318
Cdd:PTZ00449   497 APIEEEDSDKHDEPPE-------------G----PEASGLPPKAPGDKEGEEGEHEDSK---ESDEPKEGGKPGETKEGE 556

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  319 QGTSDTPASSSPPqvtsatsasssppqgtSDTPASSSPPQGTLDTPSSSSPpqgtsDTPASSSPPQgTSETPASNSPPQg 398
Cdd:PTZ00449   557 VGKKPGPAKEHKP----------------SKIPTLSKKPEFPKDPKHPKDP-----EEPKKPKRPR-SAQRPTRPKSPK- 613

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  399 tseTPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPtqvtsdtPASNSPP----------QGTSDTP 468
Cdd:PTZ00449   614 ---LPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKP-------PKSPKPPfdpkfkekfyDDYLDAA 683

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  469 GFSSPTqVTTATLVSSSPPQVTSDTPASSSPPQVTSDT--PASSSPPQVTSETPASSSPPQvtSDTSASISPPQ----VI 542
Cdd:PTZ00449   684 AKSKET-KTTVVLDESFESILKETLPETPGTPFTTPRPlpPKLPRDEEFPFEPIGDPDAEQ--PDDIEFFTPPEeertFF 760

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  543 SDTPASSSPPQVTSETPASSsptNMTSDTPASSSPTNmTSDTPASSSPTNmTSDTPA 599
Cdd:PTZ00449   761 HETPADTPLPDILAEEFKEE---DIHAETGEPDEAMK-RPDSPSEHEDKP-PGDHPS 812
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 494-650 3.47e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.62  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  494 PASSSPPQVTSdtpASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDT---PASSSPPQVTSETPASSSPTNMTSD 570
Cdd:PRK14951   366 PAAAAEAAAPA---EKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPaapPAAAPPAPVAAPAAAAPAAAPAAAP 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  571 TPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVIT--EVTRPESTIPAGRSLANITSKAQEDSPLGVISthpQMSF 648
Cdd:PRK14951   443 AAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAapAAARLTPTEEGDVWHATVQQLAAAEAITALAR---ELAL 519


                   ..
gi 1039789995  649 QS 650
Cdd:PRK14951   520 QS 521
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 354-502 3.53e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.47  E-value: 3.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  354 SSPPQGTlDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPgfssPPQVTTATLVSSSPPQVTSETPASSS 433
Cdd:PTZ00436   208 AAAPSGK-KSAKAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAP----PAKAAAPPAKAAAPPAKAAAPPAKAA 282

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  434 ptqvTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSS--PTQVTTATLVSSSPPQVTSDTPASSSPPQV 502
Cdd:PTZ00436   283 ----APPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAapPAKAAAPPAKAATPPAKAAAPPAKAAAAPV 349
PHA03193 PHA03193
tegument protein VP11/12; Provisional
 433-583 3.61e-03

tegument protein VP11/12; Provisional


Pssm-ID: 177555  Cd Length: 594  Bit Score: 41.63  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  433 SPTQVTSETPASSSPTqvtSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSD-----TPASSSPPQ-VTSDT 506
Cdd:PHA03193   441 SPFQRKRAMPEDGGEI---HEALANNGQAIFPECFSGDLPPIAQALLSADELPNDTTASTsnemkGDAECPAAQdAAAIL 517

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  507 PASSsppQVTSETPASSSPPQVTSDtsaSISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPT------NM 580
Cdd:PHA03193   518 PASF---QIENGGAADGSGLAIPAA---MCDATAVESPSTVAETPPERLLAAESGPRCKATAKHKGGSSKVEeilrrlRM 591


                   ...
gi 1039789995  581 TSD 583
Cdd:PHA03193   592 ASD 594
PPE COG5651
PPE-repeat protein [Function unknown];
295-526 3.68e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 41.42  E-value: 3.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  295 TSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSppqvtSATSASSSPPQGTSDTPASSSPPQGTldtpSSSSPPQGTS 374
Cdd:COG5651    162 VALTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPG-----FANLGLTGLNQVGIGGLNSGSGPIGL----NSGPGNTGFA 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  375 DTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSETPASSSPTQVTSDT 454
Cdd:COG5651    233 GTGAAAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGA 312

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  455 PASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSdTPASSSPPQVTSDTPASSSPPQVTSETPASSSPP 526
Cdd:COG5651    313 GGAAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAA-AAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGA 383
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 347-501 3.71e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 41.77  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  347 TSDTPASSSPPQG----TLDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTAtlVSSSPP 422
Cdd:PRK07994   367 EPEVPPQSAAPAAsaqaTAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKA--KKSEPA 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  423 QVTSETPASSSPTQVTSETPASSSPTQVTSDTPASN---SPPQGTSDTPGfSSPTQVTTATLVSSSPPQVTSDTPASSSP 499
Cdd:PRK07994   445 AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRwkaTNPVEVKKEPV-ATPKALKKALEHEKTPELAAKLAAEAIER 523


                   ..
gi 1039789995  500 PQ 501
Cdd:PRK07994   524 DP 525
CLECT smart00034
C-type lectin (CTL) or carbohydrate-recognition domain (CRD); Many of these domains function ...
 35-142 3.80e-03

C-type lectin (CTL) or carbohydrate-recognition domain (CRD); Many of these domains function as calcium-dependent carbohydrate binding modules.


Pssm-ID: 214480 [Multi-domain]  Cd Length: 124  Bit Score: 38.73  E-value: 3.80e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995    35 GNSCYQLNRLFCDFQEADNYCHAQRGRLA-------HTWnpkLRGFLKSFLNEETVW------WVRGNLTlpgshpGINQ 101
Cdd:smart00034    9 GGKCYKFSTEKKTWEDAQAFCQSLGGHLAsihseaeNDF---VASLLKNSGSSDYYWiglsdpDSNGSWQ------WSDG 79

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|....*..
gi 1039789995   102 TGGDDVLrNQKPGEcPSVVTHSNAVFS----RWNL--CIEKHHFICQ 142
Cdd:smart00034   80 SGPVSYS-NWAPGE-PNNSSGDCVVLStsggKWNDvsCTSKLPFVCE 124
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 484-607 3.92e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.09  E-value: 3.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  484 SSPPQVTSDTPA-SSSPPQVTSDTPASSSPPQVTSETP---ASSSPPQVTSDTSASISPPQVISDTPA-SSSPPQVTSET 558
Cdd:PTZ00436   219 AAAPAKAAAAPAkAAAPPAKAAAAPAKAAAAPAKAAAPpakAAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAA 298

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  559 PA--SSSPTNMTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPV 607
Cdd:PTZ00436   299 PAkaAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAPV 349
dnaA PRK14086
chromosomal replication initiator protein DnaA;
363-565 3.94e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 41.73  E-value: 3.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  363 TPSSSSPPQGTSDTPASSSP--PQGTSETPASNSPPQGTSETPGFSSPPQVTTAtlVSSSPPQVTSETPASSSPTqvtse 440
Cdd:PRK14086    89 DPSAGEPAPPPPHARRTSEPelPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTA--RPAYPAYQQRPEPGAWPRA----- 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  441 tPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPpqvtsetP 520
Cdd:PRK14086   162 -ADDYGWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPP-------P 233

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1039789995  521 ASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPT 565
Cdd:PRK14086   234 GAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPT 278
PRK10856 PRK10856
cytoskeleton protein RodZ;
391-485 3.97e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 41.17  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  391 ASNSPPQGTSE--TPGFSSPPQVTTATLVSSSPPQVTSETPASSSPT--QVTSETPASSSPTQVTSDTPASNSPPQGTSD 466
Cdd:PRK10856   152 AELSQNSGQSVplDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPapAVDPQQNAVVAPSQANVDTAATPAPAAPATP 231

                           90       100
                   ....*....|....*....|
gi 1039789995  467 TPGFSSPT-QVTTATLVSSS 485
Cdd:PRK10856   232 DGAAPLPTdQAGVSTPAADP 251
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
 417-577 4.02e-03

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 41.73  E-value: 4.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  417 VSSSPPQVTSETPASSSPTQVTS---ETPASSSPTQVTSDTPASNSPPQGTSDTPGfssptqvttatlvssspPQVTSDT 493
Cdd:pfam09786   89 VQSKSPSKGTKTPSRLTNQQLGLlglKPNDSSFVTTHRKKPPKSKSSPQSPSPVLV-----------------PLHQSVS 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  494 PASSSPPQVTSDTPASSSPPQVTSETPASSSppqvtsdtsasISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPA 573
Cdd:pfam09786  152 PSSSESRKGGDKSPAGSGKKLRSFSTSSKSP-----------ASPSVYLRGSPVPLNSSPLPSDRNYENSVQSSPEIDSA 220


                   ....
gi 1039789995  574 SSSP 577
Cdd:pfam09786  221 VSTP 224
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 345-510 4.04e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 41.77  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPAssSPPQGTLDTPSSssppQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQV 424
Cdd:PRK07994   362 AAPLPEPE--VPPQSAAPAASA----QATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSetPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFS-SPTQVTTATLVSSSPPQVTSDTPASSSPPQVT 503
Cdd:PRK07994   436 TK--AKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRwKATNPVEVKKEPVATPKALKKALEHEKTPELA 513


                   ....*..
gi 1039789995  504 SDTPASS 510
Cdd:PRK07994   514 AKLAAEA 520
PHA03193 PHA03193
tegument protein VP11/12; Provisional
 409-570 4.14e-03

tegument protein VP11/12; Provisional


Pssm-ID: 177555  Cd Length: 594  Bit Score: 41.63  E-value: 4.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  409 PQVTTATLVSSSPPqvTSETPASSSPTQVTSETPASSSPtqvtsdtPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQ 488
Cdd:PHA03193   442 PFQRKRAMPEDGGE--IHEALANNGQAIFPECFSGDLPP-------IAQALLSADELPNDTTASTSNEMKGDAECPAAQD 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  489 VTSDTPASSsppQVTSDTPASSSPPQVTSetpASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPT--- 565
Cdd:PHA03193   513 AAAILPASF---QIENGGAADGSGLAIPA---AMCDATAVESPSTVAETPPERLLAAESGPRCKATAKHKGGSSKVEeil 586


                   ....*...
gi 1039789995  566 ---NMTSD 570
Cdd:PHA03193   587 rrlRMASD 594
PRK11901 PRK11901
hypothetical protein; Reviewed
 345-530 4.62e-03

hypothetical protein; Reviewed


Pssm-ID: 237015 [Multi-domain]  Cd Length: 327  Bit Score: 40.82  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQgtsetPASNSPPQGTS--ETPGFssppqvttatlVSSSPP 422
Cdd:PRK11901    91 NQSSPSAANNTSDGHDASGVKNTAPPQDISAPPISPTPTQ-----AAPPQTPNGQQriELPGN-----------ISDALS 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  423 QVTSETPASSSPTQvtseTPASSSPTqvtsdTPASNSPPQGTSdtPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQV 502
Cdd:PRK11901   155 QQQGQVNAASQNAQ----GNTSTLPT-----APATVAPSKGAK--VPATAETHPTPPQKPATKKPAVNHHKTATVAVPPA 223

                          170       180
                   ....*....|....*....|....*....
gi 1039789995  503 TSDTPASSSPPQ-VTSETPASSSPPQVTS 530
Cdd:PRK11901   224 TSGKPKSGAASArALSSAPASHYTLQLSS 252
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 211-573 4.86e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 41.20  E-value: 4.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  211 PPKATHRMTITSLTgRPQVTSDTLASSSPPQGTSDT----PASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATS 286
Cdd:COG5180    187 EPRDALKDSPEKLD-RPKVEVKDEAQEEPPDLTGGAdhprPEAASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKERR 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  287 AsssppqgtsdTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQvtsatsasssppqgTSDTPASSSPPQGTLDTPSS 366
Cdd:COG5180    266 R----------AAIGDTPAAEPPGLPVLEAGSEPQSDAPEAETARP--------------IDVKGVASAPPATRPVRPPG 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  367 SSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSP--PQVTTATLVSSSPPQVTSETPASSSPTQVTSETPAS 444
Cdd:COG5180    322 GARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPgkPLEQGAPRPGSSGGDGAPFQPPNGAPQPGLGRRGAP 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  445 SSPtqvtsdtPASNSPPQGTSD--TPGFSSPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPAS 522
Cdd:COG5180    402 GPP-------MGAGDLVQAALDggGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADFVAPVT 474

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039789995  523 SSPPQVTSDTSASISPPQVISDTPASSSPPQVTseTPASSSPTNMTSDTPA 573
Cdd:COG5180    475 DATPVDVADVLGVRPDAILGGNVAPASGLDAET--RIIEAEGAPATEDFVA 523
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 506-577 4.89e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 41.09  E-value: 4.89e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039789995  506 TPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSP-TNMTSDTPASSSP 577
Cdd:PHA03291   204 VPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPSTTIAAPQAGTTPEAEGTPAPPTPgGGEAPPANATPAP 276
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 423-575 5.15e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 41.12  E-value: 5.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  423 QVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPPQV 502
Cdd:PRK13108   289 EYVVDEALEREPAELAAAAVASAASAVGPVGPGEPNQPDDVAEAV---KAEVAEVTDEVAAESVVQVADRDGESTPAVEE 365

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  503 TSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSP--PQVTSETPASSSPTNMTSDTPASS 575
Cdd:PRK13108   366 TSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPevPEKAAPIPDPAKPDELAVAGPGDD 440
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
364-455 5.15e-03

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 40.88  E-value: 5.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  364 PSSSSPPQGTSDTPASSSPPQGTSET---PASNSPPQGTSETpgfssPPQVTTATLVSSSPPQVTSETPASSSPtqvtSE 440
Cdd:PRK13335    80 PNTNEEKTSASKIEKISQPKQEEQKSlniSATPAPKQEQSQT-----TTESTTPKTKVTTPPSTNTPQPMQSTK----SD 150

                           90
                   ....*....|....*.
gi 1039789995  441 TPASSSPTQVTSD-TP 455
Cdd:PRK13335   151 TPQSPTIKQAQTDmTP 166
Mating_C pfam12737
C-terminal domain of homeodomain 1; Mating in fungi is controlled by the loci that determine ...
 361-598 5.30e-03

C-terminal domain of homeodomain 1; Mating in fungi is controlled by the loci that determine the mating type of an individual, and only individuals with differing mating types can mate. Basidiomycete fungi have evolved a unique mating system, termed tetrapolar or bifactorial incompatibility, in which mating type is determined by two unlinked loci; compatibility at both loci is required for mating to occur. The multi-allelic tetrapolar mating system is considered to be a novel innovation that could have only evolved once, and is thus unique to the mushroom fungi. This domain is C-terminal to the homeodomain transcription factor region.


Pssm-ID: 372279 [Multi-domain]  Cd Length: 412  Bit Score: 41.13  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  361 LDTPSSSSPPQGTSDTPASSSpPQGTSETPASNSPpqgtseTPGFSSPPQVTTATLVSSSPPQVTSEtpassspTQVTSE 440
Cdd:pfam12737  123 LDSPSSSSSPEKCLPSPAPSE-QEALSEISAACGP------TPSTLTPLNVAPSLTPSKKRKRCLSD-------GFDGPK 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  441 TPASSSPT---QVTSDT-PASNSPPQGTSDTPGFSSPtqvtTATLVSSSPPQVTSDTPASSSP-----------PQVTSD 505
Cdd:pfam12737  189 RPPNKRVQprpQTVSDPfPTSTSIPEWDEWLQNHMSP----SLTLHGDIPPPVSVEAPDSNTPldieifnfpyhPDLTPS 264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  506 TPASSSPPQVTSETPASSSPPQVTSDTSASIspPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSDTP 585
Cdd:pfam12737  265 PAPSLSDSVIEVATPTTESDYMCNGTLRQTF--SWFEFDFPELIQPTNTPASNNELSLPFDPSTDIVVSRTILPLLDWRS 342

                          250
                   ....*....|...
gi 1039789995  586 ASSSPTNMTSDTP 598
Cdd:pfam12737  343 QSFLSQTFASPPH 355
PHA03249 PHA03249
DNA packaging tegument protein UL25; Provisional
 429-561 5.94e-03

DNA packaging tegument protein UL25; Provisional


Pssm-ID: 223023  Cd Length: 653  Bit Score: 41.15  E-value: 5.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  429 PASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTsDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSS--PPQVTSDT 506
Cdd:PHA03249    33 PRPRAPTEDLDRMEAGLSSYSSSSDNKSSFEVVSET-DSGSEAEAERGRRAGMGGRNKATKPSRRNKTTQcrPTSLALAT 111

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  507 PASSSPPQVTSETPASSSPPQVTSDTS-------ASISPPQVISDTPASSSPPQVTSETPAS 561
Cdd:PHA03249   112 AATMPATPSSGKSPKVSSPPSIPSLSEedegaerNSGGDDSSHTDNESTQSQPEADDEPDLA 173
PRK10856 PRK10856
cytoskeleton protein RodZ;
346-437 5.97e-03

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 40.39  E-value: 5.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  346 GTSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSSPPQGTSETPASnsppQGTSETPGFSSPPQVTTATLVSSSPPQVT 425
Cdd:PRK10856   167 STTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPS----QANVDTAATPAPAAPATPDGAAPLPTDQA 242

                           90
                   ....*....|..
gi 1039789995  426 SETPASSSPTQV 437
Cdd:PRK10856   243 GVSTPAADPNAL 254
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
268-495 6.26e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 6.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  268 GTSDTPASSSPpqvtsATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGT 347
Cdd:PRK12323   371 GAGPATAAAAP-----VAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPG 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  348 SDTPASSSPPQgtldTPSSSSPPQGTS-DTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTS 426
Cdd:PRK12323   446 GAPAPAPAPAA----APAAAARPAAAGpRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  427 ETPASSSPTQVTSETPASSSPTQvtsdtPASNSPPQGTSDTPGFSSPTQVTTATlvSSSPPQVTSDTPA 495
Cdd:PRK12323   522 VAESIPDPATADPDDAFETLAPA-----PAAAPAPRAAAATEPVVAPRPPRASA--SGLPDMFDGDWPA 583
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
347-425 6.74e-03

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 40.49  E-value: 6.74e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  347 TSDTPASSSPPQGTLDTPSSSSPPQGTSDTPASSspPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVT 425
Cdd:PRK13335    89 ASKIEKISQPKQEEQKSLNISATPAPKQEQSQTT--TESTTPKTKVTTPPSTNTPQPMQSTKSDTPQSPTIKQAQTDMT 165
SP4_N cd22536
N-terminal domain of transcription factor Specificity Protein (SP) 4; Specificity Proteins ...
 345-655 7.71e-03

N-terminal domain of transcription factor Specificity Protein (SP) 4; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Human SP4 is a risk gene of multiple psychiatric disorders including schizophrenia, bipolar disorder, and major depression. SP4 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP4.


Pssm-ID: 411773 [Multi-domain]  Cd Length: 623  Bit Score: 40.67  E-value: 7.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  345 QGTSDTPASSSPPQGTldtpSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSetpgfsspPQVTTATLVSSSPPQV 424
Cdd:cd22536     90 QGVSAATSSAAPSSSN----NGSTSPTKVKAGNSNASAPGQFQVIQVQNMQNPSGS--------VQYQVIPQIQTVEGQQ 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  425 TSETPASSSPTQVTSET----PASS--SPTQVTSDTPASNSPPQGTSDT-------PGFSSPTQVTTatlVSSSPPQVTS 491
Cdd:cd22536    158 IQISPANATALQDLQGQiqliPAGNnqAILTTPNRTASGNIIAQNLANQtvpvqirPGVSIPLQLQT---IPGAQAQVVT 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  492 DTPASSSppQVTSDTPasssppqVTSETPASSSPPQVTSDTSASISPPQVISDTPASSSPPQVTSETPASSSPTNMT--- 568
Cdd:cd22536    235 TLPINIG--GVTLALP-------VINNVAAGGGSGQLVQPSDGGVSNGNQLVSTPITTASVSTMPESPSSSTTCTTTast 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  569 ----SDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPWPVI-TEVTRPESTIPAGRSLANITSKAQE--------DS 635
Cdd:cd22536    306 sltsSDTLVSSAETGQYASTAASSERTEEEPQTSAAESEAQSSSqLQSNGLQNVQDQSNSLQQVQIVGQPilqqiqiqQP 385

                          330       340
                   ....*....|....*....|
gi 1039789995  636 PLGVISTHPQMSFQSSTSQQ 655
Cdd:cd22536    386 QQQIIQAIQPQSFQLQSGQT 405
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 421-565 8.06e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 8.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  421 PPQVTSETPAsssptqvtsetPASSSPTQVTSDTPASNSPPQgtsdtpgfSSPTQVTTATLVSSSPPQVTSDTPASSSPP 500
Cdd:PRK14951   366 PAAAAEAAAP-----------AEKKTPARPEAAAPAAAPVAQ--------AAAAPAPAAAPAAAASAPAAPPAAAPPAPV 426

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  501 QVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASIsPPQVISDTPASSSPPQVTSETPASSSPT 565
Cdd:PRK14951   427 AAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAI-PVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 420-539 8.13e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 8.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  420 SPPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSPPQVTSDTPASSSP 499
Cdd:PRK14951   372 AAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAP 451

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1039789995  500 PQVTSDTPAsSSPPQVTSETPASSSPPQVTSDTSASISPP 539
Cdd:PRK14951   452 PAQAAPETV-AIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 377-521 8.32e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.62  E-value: 8.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  377 PASSSP-PQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQVTSETPASSSPTQVTSetpASSSPTQVTSDTP 455
Cdd:PRK07994   361 PAAPLPePEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLA---ARQQLQRAQGATK 437

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039789995  456 ASNSPPQGTSDTPgfssPTQVTTATLVSSSP-PQVTSDTPASSSPPQVTSDTPASSSPPQVTSETPA 521
Cdd:PRK07994   438 AKKSEPAAASRAR----PVNSALERLASVRPaPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKAL 500
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 489-627 8.63e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 40.48  E-value: 8.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  489 VTSDTPASSSPPQVTSDTPASSSPPQVTSETPASSSPPQVTSDTSASISPPQV-ISDTPASSSP--PQVTSETPASSSPT 565
Cdd:PHA03269    18 IIANLNTNIPIPELHTSAATQKPDPAPAPHQAASRAPDPAVAPTSAASRKPDLaQAPTPAASEKfdPAPAPHQAASRAPD 97

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039789995  566 NMTSDTPAsSSPTNMTSDTPASSS---PTNMTSDTPASSSPPWPVITEVTRPESTIpAGRSLANI 627
Cdd:PHA03269    98 PAVAPQLA-AAPKPDAAEAFTSAAqahEAPADAGTSAASKKPDPAAHTQHSPPPFA-YTRSMEHI 160
KLF12_N cd21441
N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as ...
 425-486 9.26e-03

N-terminal domain of Kruppel-like factor 12; Kruppel-like factor 12 (also known as Krueppel-like transcription factor 12, KLF12) regulates, by transcriptionally repressing Nur77 expression, endometrial decidualization, which is a prerequisite for successful implantation and the establishment of pregnancy. It is involved in the maturation processes of kidney collecting ducts after birth, and is able to increase the promoter activity of the UT-A1 urea transporter promoter by binding to the CACCC motif. KLF12 has also been found to promote colorectal cancer growth is also involved in the invasion and apoptosis of basal-like breast carcinoma. KLF12 belongs to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Although these factors bind to similar elements in vitro, they have distinct activities in vivo depending on their expression profile and the sequence of the N-terminal activation/repression domain, which differ between members. KLF12 contains an N-terminal domain that is related to the N-terminal repression domain of KLF8.


Pssm-ID: 410608 [Multi-domain]  Cd Length: 197  Bit Score: 39.22  E-value: 9.26e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039789995  425 TSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGTSDTPGFSSPTQVTTATLVSSSP 486
Cdd:cd21441     65 TSPTAVSSSPVSMTASASPSSSSSSSSSSSRPASSPTVITSVSSASSVPTVLTPGPLVASAS 126
PLN02983 PLN02983
biotin carboxyl carrier protein of acetyl-CoA carboxylase
 365-554 9.61e-03

biotin carboxyl carrier protein of acetyl-CoA carboxylase


Pssm-ID: 215533 [Multi-domain]  Cd Length: 274  Bit Score: 39.82  E-value: 9.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  365 SSSSPpqgtsdTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSSPPQvTSETPASSSPTQVTSETPAS 444
Cdd:PLN02983     3 SLSVP------CAKTAAAAANVGSRLSRSSFRLQPKPNISFPSKGPNPKRSAVPKVKAQ-LNEVAVDGSSNSAKSDDPKS 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  445 SSPTQVTSDTPASNSPPQGTSDTPGFSSP--TQVTT------------------------------------ATLVSSSP 486
Cdd:PLN02983    76 EVAPSEPKDEPPSNSSSKPNLPDEESISEfmTQVSSlvklvdsrdivelqlkqldcelvirkkealpqppppAPVVMMQP 155

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  487 PQVTSDTPASSSPPQVTSDTPASSSPPqvtseTPASSSPPQVTSDTSASISPPQ--VISDTPASSSPPQV 554
Cdd:PLN02983   156 PPPHAMPPASPPAAQPAPSAPASSPPP-----TPASPPPAKAPKSSHPPLKSPMagTFYRSPAPGEPPFV 220
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 471-600 9.72e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 40.48  E-value: 9.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039789995  471 SSPTQVTTATLVSS-----SPPQVTSDTPASSSP-PQVTSDTPASSSPPQVTSETPASSSP--PQVTSDTSASISPPQVI 542
Cdd:PHA03269    21 NLNTNIPIPELHTSaatqkPDPAPAPHQAASRAPdPAVAPTSAASRKPDLAQAPTPAASEKfdPAPAPHQAASRAPDPAV 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039789995  543 SDTPASSSPPQvtsetpASSSPTNMTSDTPASS-SPTNMTSDTPassSPTNMTSDTPAS 600
Cdd:PHA03269   101 APQLAAAPKPD------AAEAFTSAAQAHEAPAdAGTSAASKKP---DPAAHTQHSPPP 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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