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Conserved domains on  [gi|1039792244|ref|XP_017168671|]
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microtubule-associated protein 4 isoform X37 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 700-729 6.20e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 6.20e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 700 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 729
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 731-760 9.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 9.62e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 731 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 760
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 762-792 1.57e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.57e-08
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039792244 762 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 792
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 677-698 4.60e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 4.60e-07
                          10        20
                  ....*....|....*....|..
gi 1039792244 677 DLKSVRSKVGSTENIKHQPGGG 698
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 499-850 5.12e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 5.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 499 TGNDITTPPNKEPPPSPEKKAKPITEAKVAEKRTSPSKPSSAPALK-PGPK-TTPTVSKaTSPSTLVST---GPSSRSPA 573
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTtPTPNaTSPTLGK-TSPTSAVTTptpNATSPTPA 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 574 TTLPKRPTSIKTEGKPADVKRMTAKSASADlsrSKTTSASSVKRNTTPTgaapPAGMTSTRVKPMSAPSRSSGALSVDKK 653
Cdd:pfam05109 562 VTTPTPNATIPTLGKTSPTSAVTTPTPNAT---SPTVGETSPQANTTNH----TLGGTSSTPVVTSPPKNATSAVTTGQH 634

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 654 P-TSTKPSSSAPRVSRLATTVSaPDLKSVRSKVGSTENIKHQPGGGRVQIVSKKVSYSHiqskcgskdnikhvpgggnvq 732
Cdd:pfam05109 635 NiTSSSTSSMSLRPSSISETLS-PSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTH--------------------- 692

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 733 iqnkKVDISKVSSKCGSKANIKhKPGGGDVKIESQKLNFkekaqakvgsldnvghlpaggavkTEGGGSEALPCPGPPAG 812
Cdd:pfam05109 693 ----HVSTSSPAPRPGTTSQAS-GPGNSSTSTKPGEVNV------------------------TKGTPPKNATSPQAPSG 743

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1039792244 813 EEPVIPEAAPDAGAPTSASGlSGHTTLSGGGDQREPQT 850
Cdd:pfam05109 744 QKTAVPTVTSTGGKANSTTG-GKHTTGHGARTSTEPTT 780
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 700-729 6.20e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 6.20e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 700 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 729
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 731-760 9.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 9.62e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 731 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 760
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 762-792 1.57e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.57e-08
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039792244 762 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 792
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 677-698 4.60e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 4.60e-07
                          10        20
                  ....*....|....*....|..
gi 1039792244 677 DLKSVRSKVGSTENIKHQPGGG 698
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 499-850 5.12e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 5.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 499 TGNDITTPPNKEPPPSPEKKAKPITEAKVAEKRTSPSKPSSAPALK-PGPK-TTPTVSKaTSPSTLVST---GPSSRSPA 573
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTtPTPNaTSPTLGK-TSPTSAVTTptpNATSPTPA 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 574 TTLPKRPTSIKTEGKPADVKRMTAKSASADlsrSKTTSASSVKRNTTPTgaapPAGMTSTRVKPMSAPSRSSGALSVDKK 653
Cdd:pfam05109 562 VTTPTPNATIPTLGKTSPTSAVTTPTPNAT---SPTVGETSPQANTTNH----TLGGTSSTPVVTSPPKNATSAVTTGQH 634

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 654 P-TSTKPSSSAPRVSRLATTVSaPDLKSVRSKVGSTENIKHQPGGGRVQIVSKKVSYSHiqskcgskdnikhvpgggnvq 732
Cdd:pfam05109 635 NiTSSSTSSMSLRPSSISETLS-PSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTH--------------------- 692

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 733 iqnkKVDISKVSSKCGSKANIKhKPGGGDVKIESQKLNFkekaqakvgsldnvghlpaggavkTEGGGSEALPCPGPPAG 812
Cdd:pfam05109 693 ----HVSTSSPAPRPGTTSQAS-GPGNSSTSTKPGEVNV------------------------TKGTPPKNATSPQAPSG 743

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1039792244 813 EEPVIPEAAPDAGAPTSASGlSGHTTLSGGGDQREPQT 850
Cdd:pfam05109 744 QKTAVPTVTSTGGKANSTTG-GKHTTGHGARTSTEPTT 780
PHA03247 PHA03247
large tegument protein UL36; Provisional
 512-670 6.57e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  512 PPSPEKKAKPITEAKVAEKRTSPSKPsSAPALKPGPKTTPT-VSKATSPSTLVSTGPSS----RSPATTLPKRPTSIKTE 586
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALP-AAPAPPAVPAGPATpGGPARPARPPTTAGPPApappAAPAAGPPRRLTRPAVA 2789

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  587 GKPADVKRMTAKSASADLSRSKTTSASSVKRNTTP-TGAAPPAGMTSTRVKPMSAPSRSSGALS--------VDKKPTS- 656
Cdd:PHA03247  2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPaGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvapggdVRRRPPSr 2869

                          170
                   ....*....|....*...
gi 1039792244  657 ---TKPSSSA-PRVSRLA 670
Cdd:PHA03247  2870 spaAKPAAPArPPVRRLA 2887
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 604-680 4.86e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 40.26  E-value: 4.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039792244 604 LSRSKTTSASSVKRNTTPTGAAPPAgmTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKS 680
Cdd:TIGR00601  74 VSKPKTGTGKVAPPAATPTSAPTPT--PSPPASPASGMSAAPASAVEEKSPSEESATATAPESPSTSVPSSGSDAAS 148
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 700-729 6.20e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 6.20e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 700 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 729
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 731-760 9.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 9.62e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039792244 731 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 760
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 762-792 1.57e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.57e-08
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1039792244 762 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 792
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 677-698 4.60e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 4.60e-07
                          10        20
                  ....*....|....*....|..
gi 1039792244 677 DLKSVRSKVGSTENIKHQPGGG 698
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 499-850 5.12e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.30  E-value: 5.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 499 TGNDITTPPNKEPPPSPEKKAKPITEAKVAEKRTSPSKPSSAPALK-PGPK-TTPTVSKaTSPSTLVST---GPSSRSPA 573
Cdd:pfam05109 483 SGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTtPTPNaTSPTLGK-TSPTSAVTTptpNATSPTPA 561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 574 TTLPKRPTSIKTEGKPADVKRMTAKSASADlsrSKTTSASSVKRNTTPTgaapPAGMTSTRVKPMSAPSRSSGALSVDKK 653
Cdd:pfam05109 562 VTTPTPNATIPTLGKTSPTSAVTTPTPNAT---SPTVGETSPQANTTNH----TLGGTSSTPVVTSPPKNATSAVTTGQH 634

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 654 P-TSTKPSSSAPRVSRLATTVSaPDLKSVRSKVGSTENIKHQPGGGRVQIVSKKVSYSHiqskcgskdnikhvpgggnvq 732
Cdd:pfam05109 635 NiTSSSTSSMSLRPSSISETLS-PSTSDNSTSHMPLLTSAHPTGGENITQVTPASTSTH--------------------- 692

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 733 iqnkKVDISKVSSKCGSKANIKhKPGGGDVKIESQKLNFkekaqakvgsldnvghlpaggavkTEGGGSEALPCPGPPAG 812
Cdd:pfam05109 693 ----HVSTSSPAPRPGTTSQAS-GPGNSSTSTKPGEVNV------------------------TKGTPPKNATSPQAPSG 743

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1039792244 813 EEPVIPEAAPDAGAPTSASGlSGHTTLSGGGDQREPQT 850
Cdd:pfam05109 744 QKTAVPTVTSTGGKANSTTG-GKHTTGHGARTSTEPTT 780
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 519-854 6.67e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 46.49  E-value: 6.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 519 AKPITEAKVAEKRTS--PSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSiktegkpADVKRMT 596
Cdd:pfam17823  98 SEPATREGAADGAASraLAAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIA-------AASAPHA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 597 AKSASADLSRSKTTSASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPR-VSRLATTVSA 675
Cdd:pfam17823 171 ASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGtVTAAVGTVTP 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 676 PDLKSVRSKVGSTENIKHQPGGGrvQIVSKKVSYS-HIQSKCGSKDNIKHV---PGGGNVQIQNKKVDISKVSSKCGSKA 751
Cdd:pfam17823 251 AALATLAAAAGTVASAAGTINMG--DPHARRLSPAkHMPSDTMARNPAAPMgaqAQGPIIQVSTDQPVHNTAGEPTPSPS 328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 752 NIKHKPGG-GDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEALPCPGPPAGEE--PVIPEAAPDAGAPT 828
Cdd:pfam17823 329 NTTLEPNTpKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEVEATSPTTQPSPLLPTQGAagPGILLAPEQVATEA 408

                         330       340
                  ....*....|....*....|....*.
gi 1039792244 829 SASGLSGHTTLSGGGDQREPQTLDSQ 854
Cdd:pfam17823 409 TAGTASAGPTPRSSGDPKTLAMASCQ 434
PHA03247 PHA03247
large tegument protein UL36; Provisional
 512-670 6.57e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  512 PPSPEKKAKPITEAKVAEKRTSPSKPsSAPALKPGPKTTPT-VSKATSPSTLVSTGPSS----RSPATTLPKRPTSIKTE 586
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALP-AAPAPPAVPAGPATpGGPARPARPPTTAGPPApappAAPAAGPPRRLTRPAVA 2789

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  587 GKPADVKRMTAKSASADLSRSKTTSASSVKRNTTP-TGAAPPAGMTSTRVKPMSAPSRSSGALS--------VDKKPTS- 656
Cdd:PHA03247  2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPaGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvapggdVRRRPPSr 2869

                          170
                   ....*....|....*...
gi 1039792244  657 ---TKPSSSA-PRVSRLA 670
Cdd:PHA03247  2870 spaAKPAAPArPPVRRLA 2887
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 525-699 1.15e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 42.61  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 525 AKVAEKRTSPSKPSSAPALKPGPkTTPTVSKATSPStlVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADL 604
Cdd:PLN03209  321 AKIPSQRVPPKESDAADGPKPVP-TKPVTPEAPSPP--IEEEPPQPKAVVPRPLSPYTAYEDLKPPTSPIPTPPSSSPAS 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 605 SRSKTTSASSVKRNTTPTGAAPPagmTSTRVKPMSAPSRSSGALSVD------KKPTSTKPSSSAPRVSRLATTVSAPDL 678
Cdd:PLN03209  398 SKSVDAVAKPAEPDVVPSPGSAS---NVPEVEPAQVEAKKTRPLSPYaryedlKPPTSPSPTAPTGVSPSVSSTSSVPAV 474

                         170       180
                  ....*....|....*....|.
gi 1039792244 679 KSVRSKVGSTENIKHQPGGGR 699
Cdd:PLN03209  475 PDTAPATAATDAAAPPPANMR 495
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 516-726 1.63e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 516 EKKAKPITeAKVAEKRTSPSKPSSAPAlkpgPKTTPTVSKATSPSTLVS-TGPSS--RSPATTLPKRPTSIKTEGKPAD- 591
Cdd:PTZ00449  595 KKPKRPRS-AQRPTRPKSPKLPELLDI----PKSPKRPESPKSPKRPPPpQRPSSpeRPEGPKIIKSPKPPKSPKPPFDp 669

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 592 -VKRMTAKSASADLSRSKTT--------SASSVKRNTTPTGAAPPagMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSS 662
Cdd:PTZ00449  670 kFKEKFYDDYLDAAAKSKETkttvvldeSFESILKETLPETPGTP--FTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDI 747

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039792244 663 aprvsrlaTTVSAPDLKSVRSKvgstENIKHQPGGGrvqIVSKKVSYSHIQSKCGSKDNIKHVP 726
Cdd:PTZ00449  748 --------EFFTPPEEERTFFH----ETPADTPLPD---ILAEEFKEEDIHAETGEPDEAMKRP 796
PHA03247 PHA03247
large tegument protein UL36; Provisional
 528-675 1.87e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  528 AEKRTSPSKPSSAPALKPGPKTTPTVSKATS------PSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSAS 601
Cdd:PHA03247  2667 ARRLGRAAQASSPPQRPRRRAARPTVGSLTSladpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA 2746

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039792244  602 ADLSRSKTTSASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSA 675
Cdd:PHA03247  2747 GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
533-677 2.88e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.37  E-value: 2.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 533 SPSKPSSAPAlkPGPKTTPTVSKATSPSTLVSTGPSSRSPAttlPKRPTSIKTEGKPADVKRmTAKSASADLSRSKTTSA 612
Cdd:PRK07003  373 PARVAGAVPA--PGARAAAAVGASAVPAVTAVTGAAGAALA---PKAAAAAAATRAEAPPAA-PAPPATADRGDDAADGD 446

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039792244 613 SSVkRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPD 677
Cdd:PRK07003  447 APV-PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDA 510
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 532-680 4.45e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 40.68  E-value: 4.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 532 TSPSkPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKP----ADVKRMTAKSASADLSRS 607
Cdd:PLN03209  384 TSPI-PTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPyaryEDLKPPTSPSPTAPTGVS 462

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039792244 608 KTTSASSVKrnTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVD--KKPTSTKPSSSAPRVSRLATTVSAPDLKS 680
Cdd:PLN03209  463 PSVSSTSSV--PAVPDTAPATAATDAAAPPPANMRPLSPYAVYDdlKPPTSPSPAAPVGKVAPSSTNEVVKVGNS 535
rad23 TIGR00601
UV excision repair protein Rad23; All proteins in this family for which functions are known ...
 604-680 4.86e-03

UV excision repair protein Rad23; All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273167 [Multi-domain]  Cd Length: 378  Bit Score: 40.26  E-value: 4.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039792244 604 LSRSKTTSASSVKRNTTPTGAAPPAgmTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKS 680
Cdd:TIGR00601  74 VSKPKTGTGKVAPPAATPTSAPTPT--PSPPASPASGMSAAPASAVEEKSPSEESATATAPESPSTSVPSSGSDAAS 148
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 538-696 5.01e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 5.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  538 SSAPALKPGPKTTPTVSKATSPSTLVSTGPSS---------RSPATtlpkrptsikTEGKPADVKRMTAKSASADLSRSK 608
Cdd:PHA03307   253 NECPLPRPAPITLPTRIWEASGWNGPSSRPGPassssspreRSPSP----------SPSSPGSGPAPSSPRASSSSSSSR 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  609 TTSASSvkrnTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRlATTVSAPDLKSVRSKVGST 688
Cdd:PHA03307   323 ESSSSS----TSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSP-AASAGRPTRRRARAAVAGR 397


                   ....*...
gi 1039792244  689 ENIKHQPG 696
Cdd:PHA03307   398 ARRRDATG 405
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
516-667 5.46e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.24  E-value: 5.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244 516 EKKAKPITEAKVAEKRTSPSKPSSAPALKPGPKTTPTVSKATSPStlvstGPSSRSPATTLPKRPTSIKTEGKPADV--- 592
Cdd:PRK12323  423 PARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAA-----GPRPVAAAAAAAPARAAPAAAPAPADDdpp 497

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039792244 593 --KRMTAKSASADLSRSKTTSASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVS 667
Cdd:PRK12323  498 pwEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLP 574
PHA03247 PHA03247
large tegument protein UL36; Provisional
 540-676 7.74e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 7.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  540 APALKPGPKTTPTVSkaTSPSTLVSTGPSSRSPATTL-PKRPTSIKTEGKPADVKRMTAKSASAdlsrSKTTSASSVKRN 618
Cdd:PHA03247  2703 PPPPTPEPAPHALVS--ATPLPPGPAAARQASPALPAaPAPPAVPAGPATPGGPARPARPPTTA----GPPAPAPPAAPA 2776

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039792244  619 TTPTGAAPPAGMTSTRVKPMSAPSRSSGA--LSVDKKPTSTKPSSSAPRVSRLATTVSAP 676
Cdd:PHA03247  2777 AGPPRRLTRPAVASLSESRESLPSPWDPAdpPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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