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Conserved domains on  [gi|1039796670|ref|XP_017173922|]
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filamin-A isoform X3 [Mus musculus]

Protein Classification

IG_FLMN domain-containing protein( domain architecture ID 12215570)

IG_FLMN domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1388-1477 5.43e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.79  E-value: 5.43e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1388 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 1465
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670  1466 VPGSPFSVKVTG 1477
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
13-107 8.17e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.02  E-value: 8.17e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670    13 PDRVKARGPGLEKTgvAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGG 92
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670    93 VSIPNSPFRVNVGAG 107
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1209-1295 1.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 119.63  E-value: 1.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1209 ITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPG 1286
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83

                    ....*....
gi 1039796670  1287 SPFTARVTG 1295
Cdd:smart00557   84 SPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
789-883 2.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 118.86  E-value: 2.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   789 ASKVKCSGPGLSPGMVraNLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGE 868
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   869 EEVPRSPFKVKVLPT 883
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1669 3.06e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 3.06e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1579 AHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 1656
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1657 IPDSPFVVPVASP 1669
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
501-593 8.16e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 8.16e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   501 ASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQP 580
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670   581 VPNFPSKLQVEPA 593
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
886-980 5.17e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.93  E-value: 5.17e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   886 ASKVKASGPGLNttGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGG 965
Cdd:smart00557    1 ASKVKASGPGLE--KGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   966 DEIPFSPYRVRAVPT 980
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
408-497 2.65e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 110.00  E-value: 2.65e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   408 PSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTH 485
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsgKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670   486 IPGSPFKAHVAP 497
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1770-1860 1.11e-25

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 1.11e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1770 PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 1846
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79
                            90
                    ....*....|....
gi 1039796670  1847 HIGGSPFKAKVTGP 1860
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1899-1987 1.50e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 99.22  E-value: 1.50e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1899 SKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHI 1978
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                    ....*....
gi 1039796670  1979 PGSPYRIMV 1987
Cdd:smart00557   82 PGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1006-1084 2.02e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.83  E-value: 2.02e-24
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039796670  1006 QIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1084
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
597-693 4.53e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.06  E-value: 4.53e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   597 SGVQCYGPGIEGQGVFReaTTEFSVDARaltQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTY 676
Cdd:smart00557    2 SKVKASGPGLEKGVVGE--PAEFTVDTR---DAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   677 DGSPVPSSPFQVPVTEG 693
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
213-309 5.67e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 97.67  E-value: 5.67e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   213 ASKVKAEGPGLNRTGVelGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAvrDVDIIDHHDNTYTVKYIPVQQGPVGVNVTY 292
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKV--PVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   293 GGDHIPKSPFSVGVSPS 309
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
696-783 3.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 3.59e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   696 PSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQ 773
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|
gi 1039796670   774 VPGSPFKVPV 783
Cdd:smart00557   81 IPGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
110-210 1.90e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 90.36  E-value: 1.90e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   110 PNKVKVYGPGVAKTglKAHEPTYFTVDCTEAGQGDVSIGikcapgVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTI 189
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVE------VTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTV 72
                            90       100
                    ....*....|....*....|.
gi 1039796670   190 MVLFADQATPTSPIRVKVEPS 210
Cdd:smart00557   73 TVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
313-405 1.15e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.15e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   313 SKIKVSGLG-DKVDVGKDQEFTVKSKGAGGqGKVASKIVSPSGAAVPCKVEPgLGADNSVVRFVPREEGPYEVEVTYDGV 391
Cdd:smart00557    2 SKVKASGPGlEKGVVGEPAEFTVDTRDAGG-GELEVEVTGPSGKKVPVEVKD-NGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 1039796670   392 PVPGSPFPLEAVAP 405
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1673-1764 3.73e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 86.89  E-value: 3.73e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1673 ARRLTVSSLQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTH 1751
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1752 IPGSPFKIRVGEP 1764
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1142-1202 3.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 72.64  E-value: 3.77e-15
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039796670  1142 KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD 1202
Cdd:smart00557   31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1388-1477 5.43e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.79  E-value: 5.43e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1388 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 1465
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670  1466 VPGSPFSVKVTG 1477
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
13-107 8.17e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.02  E-value: 8.17e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670    13 PDRVKARGPGLEKTgvAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGG 92
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670    93 VSIPNSPFRVNVGAG 107
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1209-1295 1.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 119.63  E-value: 1.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1209 ITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPG 1286
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83

                    ....*....
gi 1039796670  1287 SPFTARVTG 1295
Cdd:smart00557   84 SPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
789-883 2.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 118.86  E-value: 2.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   789 ASKVKCSGPGLSPGMVraNLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGE 868
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   869 EEVPRSPFKVKVLPT 883
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1669 3.06e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 3.06e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1579 AHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 1656
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1657 IPDSPFVVPVASP 1669
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
501-593 8.16e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 8.16e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   501 ASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQP 580
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670   581 VPNFPSKLQVEPA 593
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
886-980 5.17e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.93  E-value: 5.17e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   886 ASKVKASGPGLNttGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGG 965
Cdd:smart00557    1 ASKVKASGPGLE--KGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   966 DEIPFSPYRVRAVPT 980
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
408-497 2.65e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 110.00  E-value: 2.65e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   408 PSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTH 485
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsgKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670   486 IPGSPFKAHVAP 497
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1770-1860 1.11e-25

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 1.11e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1770 PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 1846
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79
                            90
                    ....*....|....
gi 1039796670  1847 HIGGSPFKAKVTGP 1860
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1209-1290 7.19e-25

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 100.06  E-value: 7.19e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1209 ITAYGPGLTHGVVNKPATFTVNTKDAGeGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPG 1286
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ....
gi 1039796670 1287 SPFT 1290
Cdd:pfam00630   86 SPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1899-1987 1.50e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 99.22  E-value: 1.50e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1899 SKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHI 1978
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                    ....*....
gi 1039796670  1979 PGSPYRIMV 1987
Cdd:smart00557   82 PGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
786-877 1.71e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 98.90  E-value: 1.71e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  786 VTDASKVKCSGPGLSPGmvRANLPQSFQVDTSKAGvAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVL 865
Cdd:pfam00630    1 AADASKVKASGPGLEPG--VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 1039796670  866 YGEEEVPRSPFK 877
Cdd:pfam00630   78 FNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1006-1084 2.02e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.83  E-value: 2.02e-24
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039796670  1006 QIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1084
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1386-1471 2.94e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 98.52  E-value: 2.94e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1386 GDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGyGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFAD 1463
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*...
gi 1039796670 1464 QHVPGSPF 1471
Cdd:pfam00630   81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
597-693 4.53e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.06  E-value: 4.53e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   597 SGVQCYGPGIEGQGVFReaTTEFSVDARaltQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTY 676
Cdd:smart00557    2 SKVKASGPGLEKGVVGE--PAEFTVDTR---DAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   677 DGSPVPSSPFQVPVTEG 693
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
885-974 5.38e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 97.74  E-value: 5.38e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  885 DASKVKASGPGLNttGVPASLPVEFTIDAKDAGeGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYG 964
Cdd:pfam00630    3 DASKVKASGPGLE--PGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670  965 GDEIPFSPYR 974
Cdd:pfam00630   80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
213-309 5.67e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 97.67  E-value: 5.67e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   213 ASKVKAEGPGLNRTGVelGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAvrDVDIIDHHDNTYTVKYIPVQQGPVGVNVTY 292
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKV--PVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   293 GGDHIPKSPFSVGVSPS 309
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
11-101 1.03e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.97  E-value: 1.03e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   11 FHPDRVKARGPGLEktGVAVNKPAEFTVDAKHAGkAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSW 90
Cdd:pfam00630    2 ADASKVKASGPGLE--PGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKF 78
                           90
                   ....*....|.
gi 1039796670   91 GGVSIPNSPFR 101
Cdd:pfam00630   79 NGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
499-585 1.65e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.20  E-value: 1.65e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  499 FDASKVKCSGPGLERATAGEVGQFQVDCSSAGSaELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGG 578
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 1039796670  579 QPVPNFP 585
Cdd:pfam00630   81 QHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
696-783 3.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 3.59e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   696 PSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQ 773
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|
gi 1039796670   774 VPGSPFKVPV 783
Cdd:smart00557   81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
405-492 6.94e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.66  E-value: 6.94e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  405 PTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLtVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFA 482
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVE-VTGPdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670  483 DTHIPGSPFK 492
Cdd:pfam00630   80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1577-1663 1.21e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 93.89  E-value: 1.21e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1577 GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGaGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNE 1654
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670 1655 EHIPDSPFV 1663
Cdd:pfam00630   81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
110-210 1.90e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 90.36  E-value: 1.90e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   110 PNKVKVYGPGVAKTglKAHEPTYFTVDCTEAGQGDVSIGikcapgVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTI 189
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVE------VTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTV 72
                            90       100
                    ....*....|....*....|.
gi 1039796670   190 MVLFADQATPTSPIRVKVEPS 210
Cdd:smart00557   73 TVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
313-405 1.15e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.15e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   313 SKIKVSGLG-DKVDVGKDQEFTVKSKGAGGqGKVASKIVSPSGAAVPCKVEPgLGADNSVVRFVPREEGPYEVEVTYDGV 391
Cdd:smart00557    2 SKVKASGPGlEKGVVGEPAEFTVDTRDAGG-GELEVEVTGPSGKKVPVEVKD-NGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 1039796670   392 PVPGSPFPLEAVAP 405
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
212-302 3.41e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 86.96  E-value: 3.41e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  212 DASKVKAEGPGLNRtgVELGKPTHFTVNAKTAGkGKLDVQFSGlAKGDAVrDVDIIDHHDNTYTVKYIPVQQGPVGVNVT 291
Cdd:pfam00630    3 DASKVKASGPGLEP--GVVGKPAEFTVDTRDAG-GEGEVEVTG-PDGSPV-PVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 1039796670  292 YGGDHIPKSPF 302
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1673-1764 3.73e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 86.89  E-value: 3.73e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1673 ARRLTVSSLQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTH 1751
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1752 IPGSPFKIRVGEP 1764
Cdd:smart00557   81 IPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1768-1854 1.85e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1768 GDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGaGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGG 1844
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFNG 80
                           90
                   ....*....|
gi 1039796670 1845 pYHIGGSPFK 1854
Cdd:pfam00630   81 -QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
309-398 2.21e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 2.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  309 SLDLSKIKVSGLG-DKVDVGKDQEFTVKSKGAGGQGKVasKIVSPSGAAVPCKVEPgLGADNSVVRFVPREEGPYEVEVT 387
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAGGEGEV--EVTGPDGSPVPVEVTD-NGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 1039796670  388 YDGVPVPGSPF 398
Cdd:pfam00630   78 FNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
981-1077 1.95e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.95  E-value: 1.95e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  981 GDASKCTVTvsigghglgAGIGPTIQIGEETVITVDTKAAGkGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGK 1060
Cdd:pfam00630    2 ADASKVKAS---------GPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGD 71
                           90
                   ....*....|....*..
gi 1039796670 1061 YVICVRFGGEHVPNSPF 1077
Cdd:pfam00630   72 YTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1670-1758 2.26e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.57  E-value: 2.26e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1670 SGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG 1749
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670 1750 THIPGSPFK 1758
Cdd:pfam00630   81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
694-780 5.28e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 80.41  E-value: 5.28e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  694 CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLaVEGPSEAKMSCM--DNKDGSCSVEYIPYEAGTYSLNVTYGG 771
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVE-VTGPDGSPVPVEvtDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670  772 HQVPGSPFK 780
Cdd:pfam00630   81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
593-686 8.84e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 80.03  E-value: 8.84e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  593 AVDTSGVQCYGPGIEGQGVFREAttEFSVDARalTQTGGPHVKarVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSV 672
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPA--EFTVDTR--DAGGEGEVE--VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTV 74
                           90
                   ....*....|....
gi 1039796670  673 DVTYDGSPVPSSPF 686
Cdd:pfam00630   75 SVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1895-1984 1.59e-17

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 79.26  E-value: 1.59e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1895 PADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNmLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWG 1974
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670 1975 DEHIPGSPYR 1984
Cdd:pfam00630   80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1142-1202 3.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 72.64  E-value: 3.77e-15
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039796670  1142 KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD 1202
Cdd:smart00557   31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
108-204 5.74e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.94  E-value: 5.74e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  108 SHPNKVKVYGPGVAKTglKAHEPTYFTVDCTEA-GQGDVSIgikcapgvVGPTEADIDFDIIRNDNDTFTVKYTPCGAGS 186
Cdd:pfam00630    2 ADASKVKASGPGLEPG--VVGKPAEFTVDTRDAgGEGEVEV--------TGPDGSPVPVEVTDNGDGTYTVSYTPTEPGD 71
                           90
                   ....*....|....*...
gi 1039796670  187 YTIMVLFADQATPTSPIR 204
Cdd:pfam00630   72 YTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1138-1196 7.18e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 7.18e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039796670 1138 FTI----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSP 1196
Cdd:pfam00630   25 FTVdtrdAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1388-1477 5.43e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.79  E-value: 5.43e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1388 ASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQH 1465
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670  1466 VPGSPFSVKVTG 1477
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
13-107 8.17e-32

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 120.02  E-value: 8.17e-32
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670    13 PDRVKARGPGLEKTgvAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGG 92
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670    93 VSIPNSPFRVNVGAG 107
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1209-1295 1.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 119.63  E-value: 1.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1209 ITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPG 1286
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83

                    ....*....
gi 1039796670  1287 SPFTARVTG 1295
Cdd:smart00557   84 SPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
789-883 2.35e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 118.86  E-value: 2.35e-31
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   789 ASKVKCSGPGLSPGMVraNLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGE 868
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   869 EEVPRSPFKVKVLPT 883
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1579-1669 3.06e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 3.06e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1579 AHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEH 1656
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1657 IPDSPFVVPVASP 1669
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
501-593 8.16e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 8.16e-30
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   501 ASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQP 580
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670   581 VPNFPSKLQVEPA 593
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
886-980 5.17e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.93  E-value: 5.17e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   886 ASKVKASGPGLNttGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGG 965
Cdd:smart00557    1 ASKVKASGPGLE--KGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 1039796670   966 DEIPFSPYRVRAVPT 980
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
408-497 2.65e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 110.00  E-value: 2.65e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   408 PSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTH 485
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsgKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 1039796670   486 IPGSPFKAHVAP 497
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1770-1860 1.11e-25

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 102.68  E-value: 1.11e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1770 PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGGpY 1846
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGG-E 79
                            90
                    ....*....|....
gi 1039796670  1847 HIGGSPFKAKVTGP 1860
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1209-1290 7.19e-25

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 100.06  E-value: 7.19e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1209 ITAYGPGLTHGVVNKPATFTVNTKDAGeGGLSLAIEGPS--KAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPG 1286
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ....
gi 1039796670 1287 SPFT 1290
Cdd:pfam00630   86 SPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1899-1987 1.50e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 99.22  E-value: 1.50e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1899 SKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHI 1978
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                    ....*....
gi 1039796670  1979 PGSPYRIMV 1987
Cdd:smart00557   82 PGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
786-877 1.71e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 98.90  E-value: 1.71e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  786 VTDASKVKCSGPGLSPGmvRANLPQSFQVDTSKAGvAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVL 865
Cdd:pfam00630    1 AADASKVKASGPGLEPG--VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 1039796670  866 YGEEEVPRSPFK 877
Cdd:pfam00630   78 FNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1006-1084 2.02e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.83  E-value: 2.02e-24
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039796670  1006 QIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAG 1084
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1386-1471 2.94e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 98.52  E-value: 2.94e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1386 GDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGyGGLSLSIEGPS--KVDINTEDLEDGTCRVTYCPTEPGNYIINIKFAD 1463
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*...
gi 1039796670 1464 QHVPGSPF 1471
Cdd:pfam00630   81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
597-693 4.53e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 98.06  E-value: 4.53e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   597 SGVQCYGPGIEGQGVFReaTTEFSVDARaltQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTY 676
Cdd:smart00557    2 SKVKASGPGLEKGVVGE--PAEFTVDTR---DAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   677 DGSPVPSSPFQVPVTEG 693
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
885-974 5.38e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 97.74  E-value: 5.38e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  885 DASKVKASGPGLNttGVPASLPVEFTIDAKDAGeGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYG 964
Cdd:pfam00630    3 DASKVKASGPGLE--PGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670  965 GDEIPFSPYR 974
Cdd:pfam00630   80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
213-309 5.67e-24

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 97.67  E-value: 5.67e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   213 ASKVKAEGPGLNRTGVelGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAvrDVDIIDHHDNTYTVKYIPVQQGPVGVNVTY 292
Cdd:smart00557    1 ASKVKASGPGLEKGVV--GEPAEFTVDTRDAGGGELEVEVTGPSGKKV--PVEVKDNGDGTYTVSYTPTEPGDYTVTVKF 76
                            90
                    ....*....|....*..
gi 1039796670   293 GGDHIPKSPFSVGVSPS 309
Cdd:smart00557   77 GGEHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
11-101 1.03e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.97  E-value: 1.03e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   11 FHPDRVKARGPGLEktGVAVNKPAEFTVDAKHAGkAPLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSW 90
Cdd:pfam00630    2 ADASKVKASGPGLE--PGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKF 78
                           90
                   ....*....|.
gi 1039796670   91 GGVSIPNSPFR 101
Cdd:pfam00630   79 NGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
499-585 1.65e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.20  E-value: 1.65e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  499 FDASKVKCSGPGLERATAGEVGQFQVDCSSAGSaELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGG 578
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGG-EGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 1039796670  579 QPVPNFP 585
Cdd:pfam00630   81 QHIPGSP 87
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
696-783 3.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 3.59e-23
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   696 PSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPS--EAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQ 773
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|
gi 1039796670   774 VPGSPFKVPV 783
Cdd:smart00557   81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
405-492 6.94e-23

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.66  E-value: 6.94e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  405 PTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLtVEGP--CEAQLECLDNGDGTCSVSYVPTEPGDYNINILFA 482
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVE-VTGPdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670  483 DTHIPGSPFK 492
Cdd:pfam00630   80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1577-1663 1.21e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 93.89  E-value: 1.21e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1577 GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGaGGLAIAVEGPS--KAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNE 1654
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670 1655 EHIPDSPFV 1663
Cdd:pfam00630   81 QHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
110-210 1.90e-21

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 90.36  E-value: 1.90e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   110 PNKVKVYGPGVAKTglKAHEPTYFTVDCTEAGQGDVSIGikcapgVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTI 189
Cdd:smart00557    1 ASKVKASGPGLEKG--VVGEPAEFTVDTRDAGGGELEVE------VTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTV 72
                            90       100
                    ....*....|....*....|.
gi 1039796670   190 MVLFADQATPTSPIRVKVEPS 210
Cdd:smart00557   73 TVKFGGEHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
313-405 1.15e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.15e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670   313 SKIKVSGLG-DKVDVGKDQEFTVKSKGAGGqGKVASKIVSPSGAAVPCKVEPgLGADNSVVRFVPREEGPYEVEVTYDGV 391
Cdd:smart00557    2 SKVKASGPGlEKGVVGEPAEFTVDTRDAGG-GELEVEVTGPSGKKVPVEVKD-NGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 1039796670   392 PVPGSPFPLEAVAP 405
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
212-302 3.41e-20

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 86.96  E-value: 3.41e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  212 DASKVKAEGPGLNRtgVELGKPTHFTVNAKTAGkGKLDVQFSGlAKGDAVrDVDIIDHHDNTYTVKYIPVQQGPVGVNVT 291
Cdd:pfam00630    3 DASKVKASGPGLEP--GVVGKPAEFTVDTRDAG-GEGEVEVTG-PDGSPV-PVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 1039796670  292 YGGDHIPKSPF 302
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1673-1764 3.73e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 86.89  E-value: 3.73e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  1673 ARRLTVSSLQESGLKVNQPASFAVSLNGA-KGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTH 1751
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 1039796670  1752 IPGSPFKIRVGEP 1764
Cdd:smart00557   81 IPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1768-1854 1.85e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 1.85e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1768 GDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGaGALSVTIDGPS--KVKMDCQECPEG-YRVTYTPMAPGSYLISIKYGG 1844
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFNG 80
                           90
                   ....*....|
gi 1039796670 1845 pYHIGGSPFK 1854
Cdd:pfam00630   81 -QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
309-398 2.21e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 84.65  E-value: 2.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  309 SLDLSKIKVSGLG-DKVDVGKDQEFTVKSKGAGGQGKVasKIVSPSGAAVPCKVEPgLGADNSVVRFVPREEGPYEVEVT 387
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAGGEGEV--EVTGPDGSPVPVEVTD-NGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 1039796670  388 YDGVPVPGSPF 398
Cdd:pfam00630   78 FNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
981-1077 1.95e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.95  E-value: 1.95e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  981 GDASKCTVTvsigghglgAGIGPTIQIGEETVITVDTKAAGkGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGK 1060
Cdd:pfam00630    2 ADASKVKAS---------GPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGD 71
                           90
                   ....*....|....*..
gi 1039796670 1061 YVICVRFGGEHVPNSPF 1077
Cdd:pfam00630   72 YTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1670-1758 2.26e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.57  E-value: 2.26e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1670 SGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG 1749
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670 1750 THIPGSPFK 1758
Cdd:pfam00630   81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
694-780 5.28e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 80.41  E-value: 5.28e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  694 CDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLaVEGPSEAKMSCM--DNKDGSCSVEYIPYEAGTYSLNVTYGG 771
Cdd:pfam00630    2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVE-VTGPDGSPVPVEvtDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*....
gi 1039796670  772 HQVPGSPFK 780
Cdd:pfam00630   81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
593-686 8.84e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 80.03  E-value: 8.84e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  593 AVDTSGVQCYGPGIEGQGVFREAttEFSVDARalTQTGGPHVKarVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSV 672
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPA--EFTVDTR--DAGGEGEVE--VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTV 74
                           90
                   ....*....|....
gi 1039796670  673 DVTYDGSPVPSSPF 686
Cdd:pfam00630   75 SVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1895-1984 1.59e-17

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 79.26  E-value: 1.59e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670 1895 PADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNmLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWG 1974
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 1039796670 1975 DEHIPGSPYR 1984
Cdd:pfam00630   80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1142-1202 3.77e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 72.64  E-value: 3.77e-15
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039796670  1142 KGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD 1202
Cdd:smart00557   31 GGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
108-204 5.74e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.94  E-value: 5.74e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039796670  108 SHPNKVKVYGPGVAKTglKAHEPTYFTVDCTEA-GQGDVSIgikcapgvVGPTEADIDFDIIRNDNDTFTVKYTPCGAGS 186
Cdd:pfam00630    2 ADASKVKASGPGLEPG--VVGKPAEFTVDTRDAgGEGEVEV--------TGPDGSPVPVEVTDNGDGTYTVSYTPTEPGD 71
                           90
                   ....*....|....*...
gi 1039796670  187 YTIMVLFADQATPTSPIR 204
Cdd:pfam00630   72 YTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1138-1196 7.18e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 7.18e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039796670 1138 FTI----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSP 1196
Cdd:pfam00630   25 FTVdtrdAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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