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Conserved domains on  [gi|1207186978|ref|XP_021327021|]
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gastrula zinc finger protein XlCGF52.1-like isoform X1 [Danio rerio]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
37-353 4.20e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978  37 RTHSLKRKDKKCFTCTECGRSLSNKENLKVHMRIHTGEKPFTCSQ--CGKSFRDASNLNKHMLIHTGEKTHTCGQCSKT- 113
Cdd:COG5048    22 STLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLs 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 114 -FLRASELNDHLRVHTKeKLYSCALCGKSFANQTSLRYHQKTHTGVREYVCFEC----EKTFITAAILKQHQMIHTGEKP 188
Cdd:COG5048   102 nSKASSSSLSSSSSNSN-DNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssVNTPQSNSLHPPLPANSLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 189 YKCahcdmrfmylGSQKTHERTHTGEKPYKCSHCDKRFSRIENQKSHERIHTGEKPYMCSHCNKRFRDSKCLKQHQRI-- 266
Cdd:COG5048   181 SSN----------LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLss 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 267 ----HTGEKPYKCSHCDKRFSCIGNQKSHERMHTAEKL-YKCSHCDKRFRHLGNQKSHERT--HTRE--KPYRCSH--CD 335
Cdd:COG5048   251 sdssSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCG 330

                         330
                  ....*....|....*...
gi 1207186978 336 MRFSQLRSLKIHESIHSG 353
Cdd:COG5048   331 KLFSRNDALKRHILLHTS 348
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
37-353 4.20e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978  37 RTHSLKRKDKKCFTCTECGRSLSNKENLKVHMRIHTGEKPFTCSQ--CGKSFRDASNLNKHMLIHTGEKTHTCGQCSKT- 113
Cdd:COG5048    22 STLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLs 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 114 -FLRASELNDHLRVHTKeKLYSCALCGKSFANQTSLRYHQKTHTGVREYVCFEC----EKTFITAAILKQHQMIHTGEKP 188
Cdd:COG5048   102 nSKASSSSLSSSSSNSN-DNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssVNTPQSNSLHPPLPANSLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 189 YKCahcdmrfmylGSQKTHERTHTGEKPYKCSHCDKRFSRIENQKSHERIHTGEKPYMCSHCNKRFRDSKCLKQHQRI-- 266
Cdd:COG5048   181 SSN----------LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLss 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 267 ----HTGEKPYKCSHCDKRFSCIGNQKSHERMHTAEKL-YKCSHCDKRFRHLGNQKSHERT--HTRE--KPYRCSH--CD 335
Cdd:COG5048   251 sdssSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCG 330

                         330
                  ....*....|....*...
gi 1207186978 336 MRFSQLRSLKIHESIHSG 353
Cdd:COG5048   331 KLFSRNDALKRHILLHTS 348
zf-H2C2_2 pfam13465
Zinc-finger double domain;
260-284 6.10e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 6.10e-04
                          10        20
                  ....*....|....*....|....*
gi 1207186978 260 LKQHQRIHTGEKPYKCSHCDKRFSC 284
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 243-291 8.36e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 8.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1207186978 243 KPYmCSHCNKRFRDSKCLKQHQRIHTgekpYKCSHCDKRFSCIGNQKSH 291
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
37-353 4.20e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 4.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978  37 RTHSLKRKDKKCFTCTECGRSLSNKENLKVHMRIHTGEKPFTCSQ--CGKSFRDASNLNKHMLIHTGEKTHTCGQCSKT- 113
Cdd:COG5048    22 STLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLs 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 114 -FLRASELNDHLRVHTKeKLYSCALCGKSFANQTSLRYHQKTHTGVREYVCFEC----EKTFITAAILKQHQMIHTGEKP 188
Cdd:COG5048   102 nSKASSSSLSSSSSNSN-DNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssVNTPQSNSLHPPLPANSLSKDP 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 189 YKCahcdmrfmylGSQKTHERTHTGEKPYKCSHCDKRFSRIENQKSHERIHTGEKPYMCSHCNKRFRDSKCLKQHQRI-- 266
Cdd:COG5048   181 SSN----------LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLss 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 267 ----HTGEKPYKCSHCDKRFSCIGNQKSHERMHTAEKL-YKCSHCDKRFRHLGNQKSHERT--HTRE--KPYRCSH--CD 335
Cdd:COG5048   251 sdssSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCG 330

                         330
                  ....*....|....*...
gi 1207186978 336 MRFSQLRSLKIHESIHSG 353
Cdd:COG5048   331 KLFSRNDALKRHILLHTS 348
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 269-347 1.31e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 47.02  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 269 GEKPYKCS--HCDKRFSCIGNQKSHeRMHtaeklykcSHCDKRFRHLGNQKSHERTHTREKPYRCSHCDMRFSQLRSLKI 346
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  .
gi 1207186978 347 H 347
Cdd:COG5189   417 H 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 213-296 1.00e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.94  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 213 GEKPYKCS--HCDKRFSRIENQKSHeRIHtgekpymcSHCNKRFRDSKCLKQHQRIHTGEKPYKCSHCDKRFSCIGNQKS 290
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1207186978 291 HeRMHT 296
Cdd:COG5189   417 H-RKHS 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
84-263 1.60e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.53  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978  84 KSFRDASNLNKHMLIHTGEKT-HTCGQCSKTFLRASELNDHLR--VHTKEKLYSC----ALCGKSFANQTSLRYHQKTHT 156
Cdd:COG5048   268 ASSQSSSPNESDSSSEKGFSLpIKSKQCNISFSRSSPLTRHLRsvNHSGESLKPFscpySLCGKLFSRNDALKRHILLHT 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 157 GVREYVCF--ECEKTFITAAILKQHQMI--HTGEKPYKCAHCDMrFMYLGSQKT------HERTHTGEKP--YKCSHCDK 224
Cdd:COG5048   348 SISPAKEKllNSSSKFSPLLNNEPPQSLqqYKDLKNDKKSETLS-NSCIRNFKRdsnlslHIITHLSFRPynCKNPPCSK 426

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1207186978 225 RFSRIENQKSHERIHTgEKPYMCSHCNKRFRDSKCLKQH 263
Cdd:COG5048   427 SFNRHYNLIPHKKIHT-NHAPLLCSILKSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
187-334 3.24e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 3.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 187 KPYKCAHCDMRFMYLGSQKTHERT--HTGE--KPYKCSH--CDKRFSRIENQKSHERIHTGEKPYMC--SHCNKRFRDSK 258
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 259 --CLKQHQRIHTGEKPYKCSHCDKRFSCIG-----NQKSHERMHTAEK--LYKCSHCDKRFRHLGNQKSHERTHTREKPY 329
Cdd:COG5048   368 nnEPPQSLQQYKDLKNDKKSETLSNSCIRNfkrdsNLSLHIITHLSFRpyNCKNPPCSKSFNRHYNLIPHKKIHTNHAPL 447


                  ....*
gi 1207186978 330 RCSHC 334
Cdd:COG5048   448 LCSIL 452
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 73-156 3.89e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.40  E-value: 3.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978  73 GEKPFTCS--QCGKSFRDASNLNKHMLihtgektHtcGQCSKTFLRASELNDHLRVHTKEKLYSCALCGKSFANQTSLRY 150
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-------H--GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1207186978 151 HQKTHT 156
Cdd:COG5189   417 HRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
260-284 6.10e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 6.10e-04
                          10        20
                  ....*....|....*....|....*
gi 1207186978 260 LKQHQRIHTGEKPYKCSHCDKRFSC 284
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
63-86 6.79e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 6.79e-04
                          10        20
                  ....*....|....*....|....
gi 1207186978  63 NLKVHMRIHTGEKPFTCSQCGKSF 86
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 243-291 8.36e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 8.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1207186978 243 KPYmCSHCNKRFRDSKCLKQHQRIHTgekpYKCSHCDKRFSCIGNQKSH 291
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 185-263 1.13e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 185 GEKPYKCA--HCDMRFMYLGSQKTHeRTHtgekpykcSHCDKRFSRIENQKSHERIHTGEKPYMCSHCNKRFRDSKCLKQ 262
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  .
gi 1207186978 263 H 263
Cdd:COG5189   417 H 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 130-212 1.42e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 130 EKLYSCAL--CGKSFANQTSLRYHQKT-HTGvreyvcfecEKTFITAAILKqHQMIHTGEKPYKCAHCDMRFMYLGSQKT 206
Cdd:COG5189   347 GKPYKCPVegCNKKYKNQNGLKYHMLHgHQN---------QKLHENPSPEK-MNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1207186978 207 HeRTHT 212
Cdd:COG5189   417 H-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
205-228 3.64e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.64e-03
                          10        20
                  ....*....|....*....|....
gi 1207186978 205 KTHERTHTGEKPYKCSHCDKRFSR 228
Cdd:pfam13465   3 KRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
215-352 9.12e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 37.75  E-value: 9.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207186978 215 KPYKCSHCDKRFSRIENQKSHER--IHTGE--KPYMCSH--CNKRFRDSKCLKQHQRIHTGEKPYKC--SHCDKRFSCIG 286
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLL 367

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1207186978 287 NQKSHERMH-----TAEKLYKCSH--CDKRFRHLGNQKSHERTHTREKP--YRCSHCDMRFSQLRSLKIHESIHS 352
Cdd:COG5048   368 NNEPPQSLQqykdlKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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