|
Name |
Accession |
Description |
Interval |
E-value |
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
2785-2985 |
2.45e-109 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 347.05 E-value: 2.45e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2785 FQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA 2864
Cdd:pfam05010 1 YSQKDMDAALEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKTIAQMIEEKQKQKELEHAEIQKVLEEKDQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2865 LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQ 2944
Cdd:pfam05010 81 LADLNSVEKSFSDLFKRYEKQKEVISGYKKNEESLKKCAQDYLARIKKEEQRYQALKAHAEEKLDQANEEIAQVRSKAKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456155 2945 EQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 2985
Cdd:pfam05010 161 ETAALQASLRKEQMKVQSLERQLEQKTKENEELTKICDELI 201
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2718-2983 |
7.46e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.61 E-value: 7.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2718 AQKLQEElefaIMRIEALKLA---RQIALASRSHQDAKREAAHPTD----VSISKTALYSRigTAEVEKPAGLLFQQPDL 2790
Cdd:PTZ00121 1120 AKKKAED----ARKAEEARKAedaRKAEEARKAEDAKRVEIARKAEdarkAEEARKAEDAK--KAEAARKAEEVRKAEEL 1193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2791 DSALQIARAEIITK---EREVSEWKdKYEESRR-----EVMEMRKIVAEYEKTIAQMIEDEQR---EKSVSHQTVQQLVL 2859
Cdd:PTZ00121 1194 RKAEDARKAEAARKaeeERKAEEAR-KAEDAKKaeavkKAEEAKKDAEEAKKAEEERNNEEIRkfeEARMAHFARRQAAI 1272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2860 EKEQAL-AD--LNSVEKSLADLFRRYEKMKEVLEGFRKNEEvlKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2936
Cdd:PTZ00121 1273 KAEEARkADelKKAEEKKKADEAKKAEEKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA 1350
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1370456155 2937 QVRGKaqqeqaahQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 2983
Cdd:PTZ00121 1351 EAEAA--------ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2783-2989 |
9.35e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.15 E-value: 9.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2783 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQM-IEDEQREKSVshQTVQQLV 2858
Cdd:PRK03918 184 FIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELeKELESLEGSK--RKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2859 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANA----- 2933
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDE-LREIEKRLSRLEEEINGIEERIKELEEkeerl 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456155 2934 ------------EIAQVRGKAQQEQAAHQASLRKEQLR-------VDALERTLEQKNKEIEELTKICDELIAKMG 2989
Cdd:PRK03918 341 eelkkklkelekRLEELEERHELYEEAKAKKEELERLKkrltgltPEKLEKELEELEKAKEEIEEEISKITARIG 415
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2790-2979 |
1.59e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2790 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQMIEDEQREKsvshqtvQQLVLEKEQALA 2866
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyaLANEISRLEQQK-------QILRERLANLER 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2867 DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH---AEEKLDRANAEIAQVRGKAQ 2943
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIA 396
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1370456155 2944 qeqaahqaSLRKEQLRVDA----LERTLEQKNKEIEELTK 2979
Cdd:TIGR02168 397 --------SLNNEIERLEArlerLEDRRERLQQEIEELLK 428
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2710-2986 |
3.86e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 3.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2710 AEKnpplfAQKLQEELEfaimRIEALKLARQIALASRSHQDAKREAAhptdvsisktalysrigtaevekpagllfqqpD 2789
Cdd:COG1196 212 AER-----YRELKEELK----ELEAELLLLKLRELEAELEELEAELE--------------------------------E 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2790 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLN 2869
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEELA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2870 SVEKSLADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAH 2949
Cdd:COG1196 327 ELEEELEEL---EEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270
....*....|....*....|....*....|....*..
gi 1370456155 2950 QASLRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2986
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2790-2988 |
4.52e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 4.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2790 LDSALQIARAEIITKE-REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQmiedeqreksvshqtvqqlVLEKEQALADL 2868
Cdd:COG4717 47 LLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEE-------------------LEELEEELEEL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2869 NSVEKSLADLFRRYEKMKEVLEGFRKNEEvLKRCAQEYLSRVKKEEQRYQALKvHAEEKLDRANAEIAQVRGKAQQEQAA 2948
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEA-LEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQ 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1370456155 2949 HQASLRKE-----------QLRVDALERTLEQKNKEIEELTKICDELIAKM 2988
Cdd:COG4717 186 LSLATEEElqdlaeeleelQQRLAELEEELEEAQEELEELEEELEQLENEL 236
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
15-468 |
5.17e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.10 E-value: 5.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 15 SAQTPRSA-QPPGNSQNIKRKQQDTPGSPdhrdASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGS 93
Cdd:PHA03247 2567 SVPPPRPApRPSEPAVTSRARRPDAPPQS----ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHP 2642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 94 LLPSPPPSQEREHPSssmpfaecPPEGCLASPAAAPEDGPQTQSPRREPAPnapgdiaaafPAERDSSTPYQEIAAVPSA 173
Cdd:PHA03247 2643 PPTVPPPERPRDDPA--------PGRVSRPRRARRLGRAAQASSPPQRPRR----------RAARPTVGSLTSLADPPPP 2704
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 174 GRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEA--------------AGGFPPAES 239
Cdd:PHA03247 2705 PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPttagppapappaapAAGPPRRLT 2784
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 240 RQGVASVQVT------PEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTD-------DLEF 306
Cdd:PHA03247 2785 RPAVASLSESreslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvapggDVRR 2864
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 307 LRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPN 386
Cdd:PHA03247 2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 387 QVVCVAAGGQPEGGLPvSPEPSLLTPTEEAHPaSSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLV 466
Cdd:PHA03247 2945 PTTDPAGAGEPSGAVP-QPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPV 3022
|
..
gi 1370456155 467 GL 468
Cdd:PHA03247 3023 SL 3024
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2718-2987 |
9.11e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 9.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2718 AQKLQEELEFAIMRIEALKLARQI---ALASRSHQDAKREAAHPTDVSISKTALYSRigTAEVEKPAGLLFQQPDLDSAL 2794
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKAD 1549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2795 QIARAEIITKEREVSewkdKYEESRREvmEMRKIVAEYEKTIAQMIEdEQREKSVSHQTVQQLVLEKEQALADlnSVEKS 2874
Cdd:PTZ00121 1550 ELKKAEELKKAEEKK----KAEEAKKA--EEDKNMALRKAEEAKKAE-EARIEEVMKLYEEEKKMKAEEAKKA--EEAKI 1620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2875 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYqalKVHAEEKLDRANAEiaqvRGKAQQEQAAHQASLR 2954
Cdd:PTZ00121 1621 KAEELKKAEEEKKKVEQLKKKEAEEKKKAEE----LKKAEEEN---KIKAAEEAKKAEED----KKKAEEAKKAEEDEKK 1689
|
250 260 270
....*....|....*....|....*....|...
gi 1370456155 2955 KEQlrvdALERTLEQKNKeIEELTKICDELIAK 2987
Cdd:PTZ00121 1690 AAE----ALKKEAEEAKK-AEELKKKEAEEKKK 1717
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2729-2979 |
2.67e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.61 E-value: 2.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2729 IMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIgtAEVEKpaglLFQQPDLDSALQIARAEiitKEREV 2808
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI--EEVMK----LYEEEKKMKAEEAKKAE---EAKIK 1621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2809 SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA--LADLNSVEKSLADLFRRYEKMK 2886
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeAKKAEEDEKKAAEALKKEAEEA 1701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2887 EVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAEEKLDRANAEIAQVR-------GKAQQEQAAHQASLRKEQLR 2959
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDeeekkkiAHLKKEEEKKAEEIRKEKEA 1779
|
250 260
....*....|....*....|..
gi 1370456155 2960 V--DALERTLEQKNKEIEELTK 2979
Cdd:PTZ00121 1780 VieEELDEEDEKRRMEVDKKIK 1801
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2798-2977 |
2.78e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITKEREVseWKDKYEESRREVMEMRKIVAEYEktiaQMIEDEQREKSVSHQTVQQLVL---EKEQALADLNSVEKS 2874
Cdd:TIGR02168 219 KAELRELELAL--LVLRLEELREELEELQEELKEAE----EELEELTAELQELEEKLEELRLevsELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2875 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKaqqeqaahqasLR 2954
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LE 361
|
170 180
....*....|....*....|...
gi 1370456155 2955 KEQLRVDALERTLEQKNKEIEEL 2977
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETL 384
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2719-2987 |
3.24e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2719 QKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAhptdvsisKTALYSRigTAEVEkpagllfqqpDLDSALQIAR 2798
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEEL--------RLELEEL--ELELE----------EAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2799 AEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLNSVEKSLADL 2878
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE----EELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2879 FRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG--KAQQEQAAHQASLRKE 2956
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleEEEEEEEEALEEAAEE 450
|
250 260 270
....*....|....*....|....*....|.
gi 1370456155 2957 QLRVDALERTLEQKNKEIEELTKICDELIAK 2987
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAE 481
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2798-2987 |
3.53e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 51.45 E-value: 3.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMiEDEQreksvshQTvQQLVLEKEQALadlnsVEKsLAD 2877
Cdd:COG1340 80 RDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERL-EWRQ-------QT-EVLSPEEEKEL-----VEK-IKE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2878 LFRRYEKMKEVLEGFRKNEEVLKRCAQEylsRVKKEEQRyQALKVHAEEkLDRANAEIAQVRGKAQqeqaahqaSLRKE- 2956
Cdd:COG1340 145 LEKELEKAKKALEKNEKLKELRAELKEL---RKEAEEIH-KKIKELAEE-AQELHEEMIELYKEAD--------ELRKEa 211
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456155 2957 ----------QLRVDALERTLEQKNKEIEELTKICDELIAK 2987
Cdd:COG1340 212 delhkeiveaQEKADELHEEIIELQKELRELRKELKKLRKK 252
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2718-2970 |
4.12e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 4.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2718 AQKLQE--------ELEFAIMRIEALK-----LARQIALASRSHQDAKREAAHpTDVSISKT------------------ 2766
Cdd:TIGR02168 212 AERYKElkaelrelELALLVLRLEELReeleeLQEELKEAEEELEELTAELQE-LEEKLEELrlevseleeeieelqkel 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2767 -ALYSRIGTAEV------EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM 2839
Cdd:TIGR02168 291 yALANEISRLEQqkqilrERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2840 iEDEQREKSVSHQTVQQLVLEKEQALADLNS----VEKSLADLFRRYEKMKEVLEGFRKN-EEVLKRCAQEYLSRVKKEE 2914
Cdd:TIGR02168 371 -ESRLEELEEQLETLRSKVAQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEEL 449
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456155 2915 QRYQALKVHAEEKLDRANAEIAQVRgkaqQEQAAHQASLRKEQLRVDALERTLEQK 2970
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAE----QALDAAERELAQLQARLDSLERLQENL 501
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2721-2939 |
6.12e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 6.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2721 LQEELEFAIMRIEALKlaRQIALASRSHQDAKREAAHpTDVSISKT-----ALYSRIGTAEVEKPAgllfqqpdLDSALQ 2795
Cdd:TIGR02169 292 VKEKIGELEAEIASLE--RSIAEKERELEDAEERLAK-LEAEIDKLlaeieELEREIEEERKRRDK--------LTEEYA 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2796 IARAEIITKEREVSEWKDKYEESRREVMEMRKivaEYEKTIAQMiEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSL 2875
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYRE---KLEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456155 2876 ADLfrrYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYQALKvhaeEKLDRANAEIAQVR 2939
Cdd:TIGR02169 437 NEL---EEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLK----EEYDRVEKELSKLQ 489
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2798-2979 |
6.18e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM---IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKS 2874
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2875 LADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLR 2954
Cdd:TIGR02168 756 LTEL---EAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180
....*....|....*....|....*...
gi 1370456155 2955 K---EQLRVDALERTLEQKNKEIEELTK 2979
Cdd:TIGR02168 832 RiaaTERRLEDLEEQIEELSEDIESLAA 859
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2797-2986 |
7.36e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.99 E-value: 7.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2797 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED-----EQREKSVSHQTVQQ---------LVLEKE 2862
Cdd:TIGR02169 154 ERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQlerlrREREKAERYQALLKekreyegyeLLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2863 QALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE-EQRYQALKvhaeEKLDRANAEIAQVRGK 2941
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVK----EKIGELEAEIASLERS 309
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456155 2942 AQQEQAAHQAS---LRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2986
Cdd:TIGR02169 310 IAEKERELEDAeerLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2783-2985 |
1.04e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2783 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQ-------REKSVSHQTVQ 2855
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkekiGELEAEIASLE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2856 QLVLEKEQALADLnsvEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEkLDRANAEi 2935
Cdd:TIGR02169 308 RSIAEKERELEDA---EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE-VDKEFAE- 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2936 aqvrgkaqqeqaahqasLRKEQlrvDALERTLEQKNKEIEELTKICDELI 2985
Cdd:TIGR02169 383 -----------------TRDEL---KDYREKLEKLKREINELKRELDRLQ 412
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2786-2987 |
1.29e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2786 QQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIaqmiedEQREKSVSHQTVQQLVLEKEQAL 2865
Cdd:COG4942 49 EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL------EAQKEELAELLRALYRLGRQPPL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2866 ADLNSVEkSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQE 2945
Cdd:COG4942 123 ALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRA-DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1370456155 2946 qaahqasLRKEQLRVDALERTLEQKNKEIEELTKICDELIAK 2987
Cdd:COG4942 201 -------LARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2776-2984 |
1.35e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2776 EVEKPAGLLFQQPdldSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 2855
Cdd:PRK03918 311 EIEKRLSRLEEEI---NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2856 QLVLE-------KEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK------------NEEVLKRCAQEYLSRVKKEEQR 2916
Cdd:PRK03918 388 KLEKEleelekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456155 2917 YQALKvHAEEKLDRANAEIAQVRGKAQQ--EQAAHQASLR--KEQLRVDALERtLEQKNKEIEELTKICDEL 2984
Cdd:PRK03918 468 LKEIE-EKERKLRKELRELEKVLKKESEliKLKELAEQLKelEEKLKKYNLEE-LEKKAEEYEKLKEKLIKL 537
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2798-2986 |
2.42e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 2.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAE------YEKTIAQMIEDEQREKSVSHQTV----------------- 2854
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELekkaeeyeklkeklikl 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2855 --QQLVLEKEqaLADLNSVEKSLADLFRRYEKMKEVL---------EGFRKNEEV------LKRCAQEYL------SRVK 2911
Cdd:PRK03918 538 kgEIKSLKKE--LEKLEELKKKLAELEKKLDELEEELaellkeleeLGFESVEELeerlkeLEPFYNEYLelkdaeKELE 615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2912 KEEQRYQALK---VHAEEKLDRANAEIAQVRGK----AQQEQAAHQASLRKEQLRvdaLERTLEQKNKEIEELTKICDEL 2984
Cdd:PRK03918 616 REEKELKKLEeelDKAFEELAETEKRLEELRKEleelEKKYSEEEYEELREEYLE---LSRELAGLRAELEELEKRREEI 692
|
..
gi 1370456155 2985 IA 2986
Cdd:PRK03918 693 KK 694
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
2165-2552 |
2.86e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.07 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2165 SGENLASETKTESAKTEGPSpalleETPLEPAVGPKAacPLDSESAEGVVPPASGggrvQNSPPVGRKtlPLTTapEAGE 2244
Cdd:PTZ00449 492 SKKKLAPIEEEDSDKHDEPP-----EGPEASGLPPKA--PGDKEGEEGEHEDSKE----SDEPKEGGK--PGET--KEGE 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2245 VTPSDSGGQEDSPAK--GLSVRLEFDySEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPeKLDNTPASP--PR 2320
Cdd:PTZ00449 557 VGKKPGPAKEHKPSKipTLSKKPEFP-KDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIP-KSPKRPESPksPK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2321 SPAEPNDiPIAKgtytfdidkwDDPNFNPFSSTSKMQESPKLPqqsynFDPDTCDESVDPFktssktpsspskspasfei 2400
Cdd:PTZ00449 635 RPPPPQR-PSSP----------ERPEGPKIIKSPKPPKSPKPP-----FDPKFKEKFYDDY------------------- 679
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2401 pasameangvdgdgLNKPAKKKKTPLKTMVEDVMSVCSLFDTFRVKKSPKRSPLSDPPSQdPTPAATPETPPvisavvHA 2480
Cdd:PTZ00449 680 --------------LDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKL-PRDEEFPFEPI------GD 738
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370456155 2481 TDEEKlavtnqkwtcmtvdlEADKQDYPQPSDLSTFVNETKFSSPTEGKQLCSQLDPHSASENPAPREPKAR 2552
Cdd:PTZ00449 739 PDAEQ---------------PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEAMKR 795
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
87-668 |
3.23e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 3.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 87 ARGPEGSLLPSPPPSQerehPSSSMPFAEC---PPEGCLASPAAAPEDGPQTQSPRrepapnAPGDIAAAFPAerdsstP 163
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAA----PDRSVPPPRPaprPSEPAVTSRARRPDAPPQSARPR------APVDDRGDPRG------P 2611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 164 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGidqSPGMSPVPLRePMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV 243
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPH---PPPTVPPPER-PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA 2687
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 244 ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAP-RASDRERGQGEAPPqyltddleflrachlPRSNSGAAPE 322
Cdd:PHA03247 2688 ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAaRQASPALPAAPAPP---------------AVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 323 AEVNAASQESCQQPVGAYLPHAelPWGLPSPALVPEAGGSGKEALDTIDVQGHPqtgmrgTKPNQVVCVAAGGQPEGGLP 402
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAA--PAAGPPRRLTRPAVASLSESRESLPSPWDP------ADPPAAVLAPAAALPPAASP 2824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 403 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDaglvglerqvsdlgskgehp 482
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVR-------------------- 2884
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 483 egdpgEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSP 562
Cdd:PHA03247 2885 -----RLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 563 AVAKEGSRSPGD---------SPGGKEEAPEPP-----DGGDPGNLQGEDSQAFSSKRDP-EVGKDELSKPSSDAESRDH 627
Cdd:PHA03247 2960 PQPWLGALVPGRvavprfrvpQPAPSREAPASStppltGHSLSRVSSWASSLALHEETDPpPVSLKQTLWPPDDTEDSDA 3039
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1370456155 628 PSSHSAQPPRKGGAG---HTDGPHSQTAEADASGLPHKLGEEDP 668
Cdd:PHA03247 3040 DSLFDSDSERSDLEAldpLPPEPHDPFAHEPDPATPEAGARESP 3083
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2794-2935 |
4.01e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 4.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2794 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKI--VAEYEKtiaqmIEDEQREKSVSHQTVQQlvlEKEQALADLNSV 2871
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKysEEEYEE-----LREEYLELSRELAGLRA---ELEELEKRREEI 692
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370456155 2872 EKSLADLFRRYEKMKEVlegfRKNEEVLKRcAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEI 2935
Cdd:PRK03918 693 KKTLEKLKEELEEREKA----KKELEKLEK-ALERVEELREKVKKYKALlKERALSKVGEIASEI 752
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2816-2979 |
4.43e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.75 E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2816 EESRREVMEMRKIVAEYEKTIAQmIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN 2895
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREE-LEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2896 EEVLkrcaQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQvrgkaqqeqaahqaslRKEQLRvdALERTLEQKNKEIE 2975
Cdd:COG4372 110 AEEL----QEELEELQKERQDLEQQRKQLEAQIAELQSEIAE----------------REEELK--ELEEQLESLQEELA 167
|
....
gi 1370456155 2976 ELTK 2979
Cdd:COG4372 168 ALEQ 171
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2708-2911 |
4.51e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2708 DLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDvsiSKTALYSRIGTAEvEKPAGLLFQQ 2787
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE---ELQRLSEELADLN-AAIAGIEAKI 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2788 PDLDSALQIARAEIITKEREVSEWKDKYEESRRevmEMRKIVAEYEKtiaqmIEDEQREKS-----------VSHQTV-- 2854
Cdd:TIGR02169 437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ---ELYDLKEEYDR-----VEKELSKLQrelaeaeaqarASEERVrg 508
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370456155 2855 ---QQLVLEkeqalADLNSVEKSLADLFR---RYEKMKEVLEGFR------KNEEVLKRCAqEYLSRVK 2911
Cdd:TIGR02169 509 graVEEVLK-----ASIQGVHGTVAQLGSvgeRYATAIEVAAGNRlnnvvvEDDAVAKEAI-ELLKRRK 571
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2798-2990 |
5.06e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.98 E-value: 5.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITkerEVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE------DEQREKSVSHQTVQQLVLEKEQALADLNSV 2871
Cdd:COG1340 31 RDELNE---ELKELAEKRDELNAQVKELREEAQELREKRDELNEkvkelkEERDELNEKLNELREELDELRKELAELNKA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2872 EKSLADLFRRYEKMK-----EVLeGFRKNEEVLKRCAQ--EYLSRVKKEEQ----------RYQALKVHAE--------- 2925
Cdd:COG1340 108 GGSIDKLRKEIERLEwrqqtEVL-SPEEEKELVEKIKEleKELEKAKKALEkneklkelraELKELRKEAEeihkkikel 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370456155 2926 -EKLDRANAEIAQVRGKaqqeqaahQASLRKEqlrVDALERTLEQKNKEIEELTKICDELIAKMGK 2990
Cdd:COG1340 187 aEEAQELHEEMIELYKE--------ADELRKE---ADELHKEIVEAQEKADELHEEIIELQKELRE 241
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
2719-2979 |
5.26e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.80 E-value: 5.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2719 QKLQEELEFAIMRIEALKLARQIALA--SRSHQDAKREaahpTDVSIsktalysRIGTAEVEKpagllfQQPDLDSALQI 2796
Cdd:COG5185 296 EKIAEYTKSIDIKKATESLEEQLAAAeaEQELEESKRE----TETGI-------QNLTAEIEQ------GQESLTENLEA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2797 ARAEII---------TKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED---EQREKSVSHQT-VQQLVLEKEQ 2863
Cdd:COG5185 359 IKEEIEnivgevelsKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDtlkAADRQIEELQRqIEQATSSNEE 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2864 ALADLNSVEKSLADLFRR---------YEKMKEVLEGFRKNEEVLKRcaqeylsRVKKEEQRYQALKVHAEEKLDRANAE 2934
Cdd:COG5185 439 VSKLLNELISELNKVMREadeesqsrlEEAYDEINRSVRSKKEDLNE-------ELTQIESRVSTLKATLEKLRAKLERQ 511
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1370456155 2935 IAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2979
Cdd:COG5185 512 LEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNA 556
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2784-2976 |
8.65e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.59 E-value: 8.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2784 LFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2863
Cdd:COG4372 37 LFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE----LNEQLQAAQAELAQAQEELESLQEEAEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2864 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEIAQV---- 2938
Cdd:COG4372 113 LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALeQELQALSEAEAEQALDELlkea 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 1370456155 2939 -RGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2976
Cdd:COG4372 193 nRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2793-2977 |
9.53e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 9.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2793 ALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI----------------VAEYEKTIAQmIEDEQREKSVSHQTVQQ 2856
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERrealqrlaeyswdeidVASAEREIAE-LEAELERLDASSDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2857 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2936
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD-RLEAAEDLARLELRALLEERFAAALGDAVERELR 768
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1370456155 2937 QvrgkaqqeqaahqaSLRKeqlRVDALERTLEQKNKEIEEL 2977
Cdd:COG4913 769 E--------------NLEE---RIDALRARLNRAEEELERA 792
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2731-2987 |
1.66e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2731 RIEALKLARQialASRSHQDAKR--------EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEII 2802
Cdd:PTZ00121 1225 KAEAVKKAEE---AKKDAEEAKKaeeernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2803 TKEREV---SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALAD--LNSVEKSLAD 2877
Cdd:PTZ00121 1302 KKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2878 LFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEE--KLDRANAEIAQVR----GKAQQEQAAHQA 2951
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKkadeAKKKAEEAKKAE 1460
|
250 260 270
....*....|....*....|....*....|....*....
gi 1370456155 2952 SLRK---EQLRVDALERTLEQKNKEiEELTKICDELIAK 2987
Cdd:PTZ00121 1461 EAKKkaeEAKKADEAKKKAEEAKKA-DEAKKKAEEAKKK 1498
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
73-475 |
1.82e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 1.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 73 VSPEVTEPRKDPQGARGPEGSLLPSP----PPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG 148
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPaaaaPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 149 DIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQS--PGMSPVPLREPMKAPLCGEGDQPGGFESQ 226
Cdd:PRK07764 467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwpEILAAVPKRSRKTWAILLPEATVLGVRGD 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 227 E---KEAAGGFPPAESRQGVASV-----------QVTPEA-----PAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASD 287
Cdd:PRK07764 547 TlvlGFSTGGLARRFASPGNAEVlvtalaeelggDWQVEAvvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 288 RERGQGEAPPQYLTDDleflRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEAL 367
Cdd:PRK07764 627 PAPAGAAAAPAEASAA----PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 368 DTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSllTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSK 447
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
410 420
....*....|....*....|....*...
gi 1370456155 448 AGMPVSADAAKEVVDAGLVGLERQVSDL 475
Cdd:PRK07764 781 EEEEMAEDDAPSMDDEDRRDAEEVAMEL 808
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2795-2969 |
1.86e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2795 QIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQ-TVQQLVLEKEQALADLNSVEK 2873
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlQLLPLYQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2874 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE--------------YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVR 2939
Cdd:COG4717 147 RLEELEERLEELRELEEELEELEAELAELQEEleelleqlslateeELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
|
170 180 190
....*....|....*....|....*....|
gi 1370456155 2940 GKAQQEqaahqaslrKEQLRVDALERTLEQ 2969
Cdd:COG4717 227 EELEQL---------ENELEAAALEERLKE 247
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2795-2987 |
3.81e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 45.68 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2795 QIARAEIITKEREvsewkdkyEESRREVMEMRKivaEYEKTIAQMIEDEQREKSVSHQTVQQLV-----------LEKEQ 2863
Cdd:pfam13868 27 QIAEKKRIKAEEK--------EEERRLDEMMEE---ERERALEEEEEKEEERKEERKRYRQELEeqieereqkrqEEYEE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2864 ALADLNSV--------EKSLADLFRRYEKMKEVLEGFRK-NEEVLKRCAQEYLsRVKKEEQRYQAlkvHAEEKLDRANAE 2934
Cdd:pfam13868 96 KLQEREQMdeiveriqEEDQAEAEEKLEKQRQLREEIDEfNEEQAEWKELEKE-EEREEDERILE---YLKEKAEREEER 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456155 2935 IAQVRGKAqqeqaahqaslRKEQLRVDALERTLEQKNKEIEELtkicDELIAK 2987
Cdd:pfam13868 172 EAEREEIE-----------EEKEREIARLRAQQEKAQDEKAER----DELRAK 209
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
238-602 |
4.83e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 238 ESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNS 317
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 318 GAAPEAEVNAASQESCQQPVGAYLPHAElPWGLPSPALVPEAGGSGKEAlDTID-------------------------- 371
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPA-PAAAPAAPAAPAAPAGADDA-ATLRerwpeilaavpkrsrktwaillpeat 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 372 ---------VQGHPQTGMRG--TKPN-----------------QVVCVAAGGQPEGGLPVSPEP-SLLTPTEEAHPASSL 422
Cdd:PRK07764 540 vlgvrgdtlVLGFSTGGLARrfASPGnaevlvtalaeelggdwQVEAVVGPAPGAAGGEGPPAPaSSGPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 423 ASF--PAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGeh 500
Cdd:PRK07764 620 APAapAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA-- 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 501 lnteQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARG---------PPGPTDGAKVHEDSTSPAVAKEGSRS 571
Cdd:PRK07764 698 ----PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAA 773
|
410 420 430
....*....|....*....|....*....|.
gi 1370456155 572 PGDSPGGKEEAPEPPDGGDPGNLQGEDSQAF 602
Cdd:PRK07764 774 PPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1523-1987 |
8.01e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 8.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1523 PTLREDERPEGPGAAWPGLE----GQAYSQLERSRQELASGLPS-PAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSG 1597
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAqASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEP 2710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1598 KQHQETSACDSPHGEDGPGDFAH----TGVPGHVPRSTCAPS----PQREVLTVPEANSEPWTLDTLGGERR--PGVTAG 1667
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPalpaAPAPPAVPAGPATPGgparPARPPTTAGPPAPAPPAAPAAGPPRRltRPAVAS 2790
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1668 ILEMRNALGNQSTPAPPTGEV-ADTPLEPGKVAGAAGEAEGDITLSTAEtqACASGDLPEAGTTRTFSVVAGDLVLPGSC 1746
Cdd:PHA03247 2791 LSESRESLPSPWDPADPPAAVlAPAAALPPAASPAGPLPPPTSAQPTAP--PPPPGPPPPSLPLGGSVAPGGDVRRRPPS 2868
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1747 QDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPagdgkvcvSSPPEPDETHDPKLQHLAPEELHTDRESPRPG 1826
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP--------PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1827 PSMLPSVPKKDAPRVMDKVtSDETRGAEGTESSPVADDIIQPAAPAdLESPTLAASSYHGDVVGQVSTdlIAQSISPAAA 1906
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAV-PQPWLGALVPGRVAVPRFRVPQPAPS-REAPASSTPPLTGHSLSRVSS--WASSLALHEE 3016
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1907 HAGLPPSAAEHIVSPSAPAGDRVEASTPScpDPAKDLSRSSDSEeafeTPESTTPVKAPPAPPPPPPEVIPEPEVSTQPP 1986
Cdd:PHA03247 3017 TDPPPVSLKQTLWPPDDTEDSDADSLFDS--DSERSDLEALDPL----PPEPHDPFAHEPDPATPEAGARESPSSQFGPP 3090
|
.
gi 1370456155 1987 P 1987
Cdd:PHA03247 3091 P 3091
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2797-2930 |
9.21e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 9.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2797 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTI----AQMIE-----DEQREKSVS-HQTVQqlvlEKEQALA 2866
Cdd:COG1340 151 KAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAqelhEEMIElykeaDELRKEADElHKEIV----EAQEKAD 226
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456155 2867 DLNsveKSLADLFRRYEKMKEVLEGFRKNEEVLKRcaqeylsrvKKEEQRYQALKVHAEEKLDR 2930
Cdd:COG1340 227 ELH---EEIIELQKELRELRKELKKLRKKQRALKR---------EKEKEELEEKAEEIFEKLKK 278
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
221-695 |
1.02e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 221 GGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAqqgtesSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPP--- 297
Cdd:PHA03307 17 GGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAA------VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTptw 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 298 QYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGkealdtidvqghpq 377
Cdd:PHA03307 91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAG-------------- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 378 tgmrgtkpnqvvcvAAGGQPEGGLPVSPEPSLLTPTEEAH---PASSLASFPAAQIPIAVEEPGSS-SRESVSKAGMPVS 453
Cdd:PHA03307 157 --------------ASPAAVASDAASSRQAALPLSSPEETaraPSSPPAEPPPSTPPAAASPRPPRrSSPISASASSPAP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 454 ADAAKEVVDAG-----LVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQShevqpgvpppplpkEQSHEVQP 528
Cdd:PHA03307 223 APGRSAADDAGasssdSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSS--------------RPGPASSS 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 529 GAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDP 608
Cdd:PHA03307 289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 609 EvgkdelskPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIW 688
Cdd:PHA03307 369 P--------RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPW 440
|
....*..
gi 1370456155 689 EGSGLQP 695
Cdd:PHA03307 441 PGSPPPP 447
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1748-2035 |
1.02e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1748 DPACSDKAPGMEGTAAlhgDSPARPQQaKEQPGPERPIPAGDGKVcVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP 1827
Cdd:PHA03307 46 DSAELAAVTVVAGAAA---CDRFEPPT-GPPPGPGTEAPANESRS-TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1828 SMLPSVPKKDAPRVmdkvtSDETRGAEGTESSPVADDIIQPAAPADLESPTlaASSYHGDVVGQVSTDLIAQSISPAAAh 1907
Cdd:PHA03307 121 PPPASPPPSPAPDL-----SEMLRPVGSPGPPPAASPPAAGASPAAVASDA--ASSRQAALPLSSPEETARAPSSPPAE- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1908 agLPPSAAEHIVSPSAPAGDRVEASTPSCPDP------AKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEV 1981
Cdd:PHA03307 193 --PPPSTPPAAASPRPPRRSSPISASASSPAPapgrsaADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1370456155 1982 STQPP-PEEPGCGSE----TVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 2035
Cdd:PHA03307 271 EASGWnGPSSRPGPAssssSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST 329
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2797-2976 |
1.86e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 43.37 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2797 ARAEIITKEREVSEWKDKYEEsrREVMEMRKIvAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVL-----------EKE 2862
Cdd:pfam13868 128 LREEIDEFNEEQAEWKELEKE--EEREEDERI-LEYLKEKAEreeEREAEREEIEEEKEREIARLRaqqekaqdekaERD 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2863 QALADLNSVE-------KSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAE-EKLDRANAE 2934
Cdd:pfam13868 205 ELRAKLYQEEqerkerqKEREEAEKKARQRQELQQAREEQIELKERRLAEE--AEREEEEFERMLRKQAEdEEIEQEEAE 282
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456155 2935 iaQVRGKAQQEQAAHQASLR-KEQLRVDALERTLEQKNKEIEE 2976
Cdd:pfam13868 283 --KRRMKRLEHRRELEKQIEeREEQRAAEREEELEEGERLREE 323
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2712-2904 |
2.07e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2712 KNPPLFAQKLqEELEfaimriEALKLARQIALASRSHQDAKREA-AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdl 2790
Cdd:COG4717 64 RKPELNLKEL-KELE------EELKEAEEKEEEYAELQEELEELeEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2791 dsaLQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNS 2870
Cdd:COG4717 134 ---LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210
|
170 180 190
....*....|....*....|....*....|....
gi 1370456155 2871 VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 2904
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2814-2990 |
2.33e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 2.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2814 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEgfR 2893
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE--E 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2894 KNEEVLKrcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRgkaqqeqaahqasLRKEQL--RVDALERTLEQKN 2971
Cdd:COG4372 85 LNEQLQA--AQAELAQAQEELESLQEEAEELQEELEELQKERQDLE-------------QQRKQLeaQIAELQSEIAERE 149
|
170
....*....|....*....
gi 1370456155 2972 KEIEELTKICDELIAKMGK 2990
Cdd:COG4372 150 EELKELEEQLESLQEELAA 168
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2595-2976 |
2.34e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 2.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2595 DTSQESPVKSSPVRM-SESPTPCS-GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQvpeKSSQKELEAMGLGTPSEA 2672
Cdd:pfam17380 181 RRRGNHSAFTRPGRPrTTTPMPVThATRFVPGIQMSTVAPKEVQGMPHTLAPYEKMERR---KESFNLAEDVTTMTPEYT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2673 IEITapeGSFASADALLSRLAHPVSLCGALDylEPDLAEKNPPLFAQKLQEELEFAIMRIEAlklARQIALASRSHQDA- 2751
Cdd:pfam17380 258 VRYN---GQTMTENEFLNQLLHIVQHQKAVS--ERQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAEKARQAEm 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2752 KREA---AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdlDSALQIARAEIItkEREVSEWKDKYEESRREVMEMRKi 2828
Cdd:pfam17380 330 DRQAaiyAEQERMAMERERELERIRQEERKRELERIRQE---EIAMEISRMREL--ERLQMERQQKNERVRQELEAARK- 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2829 vaeyektiaQMIEDEQREKSVSHQTVQQLVLEKEQaladlnsvEKSLADLFRRYEKMKEvLEGFRKNEEVLKRCAQEYLS 2908
Cdd:pfam17380 404 ---------VKILEEERQRKIQQQKVEMEQIRAEQ--------EEARQREVRRLEEERA-REMERVRLEEQERQQQVERL 465
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370456155 2909 RVKKEEQRYQALKVHAEEKlDRANAEiAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2976
Cdd:pfam17380 466 RQQEEERKRKKLELEKEKR-DRKRAE-EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2792-2979 |
2.45e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2792 SALQIARAEIITKE--REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM-------------IEDEQREKsvsHQTVQQ 2856
Cdd:TIGR04523 298 SDLNNQKEQDWNKElkSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLkkeltnsesenseKQRELEEK---QNEIEK 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2857 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKrcaQEYLSrVKKEEQRYQALKVHAEEKLDRANAEIA 2936
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ---QEKEL-LEKEIERLKETIIKNNSEIKDLTNQDS 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456155 2937 ----------QVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2979
Cdd:TIGR04523 451 vkeliiknldNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
69-299 |
2.53e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.62 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 69 DPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG 148
Cdd:PHA03307 131 APDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 149 DIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEK 228
Cdd:PHA03307 211 SPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSS 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 229 EAAGGFPPAESRQGV--------ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI--------PQDPAPRASDRERGQ 292
Cdd:PHA03307 291 PRERSPSPSPSSPGSgpapssprASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPsrspspsrPPPPADPSSPRKRPR 370
|
....*..
gi 1370456155 293 GEAPPQY 299
Cdd:PHA03307 371 PSRAPSS 377
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2798-2983 |
3.15e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 3.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2798 RAEIITKEREVsewkdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTV--QQLVLEKEQALADLNSVEKSL 2875
Cdd:pfam02463 185 LAELIIDLEEL-------KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLneERIDLLQELLRDEQEEIESSK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2876 ADLFRRYEKMKEVLEGFRKNEEVLK-----------RCAQEYLSRVKKEEQRYQALK--VHAEEKLDRANAEIAQVRGKA 2942
Cdd:pfam02463 258 QEIEKEEEKLAQVLKENKEEEKEKKlqeeelkllakEEEELKSELLKLERRKVDDEEklKESEKEKKKAEKELKKEKEEI 337
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1370456155 2943 QQEQAAHQASLRKEQL----RVDALERTLEQKNKEIEELTKICDE 2983
Cdd:pfam02463 338 EELEKELKELEIKREAeeeeEEELEKLQEKLEQLEEELLAKKKLE 382
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
16-347 |
3.32e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 3.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 16 AQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVS---PEVTEPRKDPQGARGPEG 92
Cdd:PHA03307 118 PPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLsspEETARAPSSPPAEPPPST 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 93 SLLPSPPPSQEREHPSSSmpFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPS 172
Cdd:PHA03307 198 PPAAASPRPPRRSSPISA--SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGW 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 173 AGRERQPKEEGQKSSFSFSSGiDQSPGMSPVPLREPMKAPLCGEGDQP-----GGFESQEKEAAGGFPPAESRQGVASVQ 247
Cdd:PHA03307 276 NGPSSRPGPASSSSSPRERSP-SPSPSSPGSGPAPSSPRASSSSSSSRessssSTSSSSESSRGAAVSPGPSPSRSPSPS 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 248 VTPEAPAAAQQGtessavleKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNA 327
Cdd:PHA03307 355 RPPPPADPSSPR--------KRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAF 426
|
330 340
....*....|....*....|
gi 1370456155 328 ASQESCQQPVGAYLPHAELP 347
Cdd:PHA03307 427 YARYPLLTPSGEPWPGSPPP 446
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
69-286 |
3.40e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 3.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 69 DPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAA-PEDGPQTQSPRREPAPNAP 147
Cdd:PHA03307 52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPsSPDPPPPTPPPASPPPSPA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 148 GDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLRE--PMKAPLCGEGDQPGGFES 225
Cdd:PHA03307 132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAepPPSTPPAAASPRPPRRSS 211
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370456155 226 QEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRAS 286
Cdd:PHA03307 212 PISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEA 272
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1627-2017 |
4.39e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1627 VPRSTCAPSPQREVLTV----PEANSEPWTLDTLGGERRPgvtagilemrNALGNQSTPAPPTGEVADTPlePGKVAGAA 1702
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVTSrarrPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLPPDTHAPDPP--PPSPSPAA 2635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1703 GEAEGDITLSTAETQ----ACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHgDSPARPQQAKEQ 1778
Cdd:PHA03247 2636 NEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPP-PPPPTPEPAPHA 2714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1779 PGPERPIPAGDGKVCVSSPPEPDETHDPKlqhlAPEELHTDRESPRPGPSMLPSVPKKDAPrvmdkvtsdetrgAEGTES 1858
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPAAPAPPA----VPAGPATPGGPARPARPPTTAGPPAPAP-------------PAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1859 SPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAhAGLPPSAAEHIVSPSAPAGDrVEASTPSCPD 1938
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-GPLPPPTSAQPTAPPPPPGP-PPPSLPLGGS 2855
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 1939 --PAKDLSRSSDSEEAFETPESTTPV-----KAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGS 2011
Cdd:PHA03247 2856 vaPGGDVRRRPPSRSPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
|
....*.
gi 1370456155 2012 PFRPPS 2017
Cdd:PHA03247 2936 PPRPQP 2941
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
2770-2941 |
4.96e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.17 E-value: 4.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2770 SRIGTAEVEKpagllfqqpdlDSALQIARAEiitKEREVSEwkdkyEESRREVMEMRkiVAEYEKTIAQMIEDEQREKsv 2849
Cdd:COG2268 201 ARIAEAEAER-----------ETEIAIAQAN---REAEEAE-----LEQEREIETAR--IAEAEAELAKKKAEERREA-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2850 shqtvqqlvlEKEQALADLnSVEKsladlfRRYEKMKEV---LEGFRKNEEVLkrcAQEylSRVKKEEQRYQA---LKVH 2923
Cdd:COG2268 258 ----------ETARAEAEA-AYEI------AEANAEREVqrqLEIAEREREIE---LQE--KEAEREEAELEAdvrKPAE 315
|
170 180
....*....|....*....|..
gi 1370456155 2924 AE----EKLDRANAEIAQVRGK 2941
Cdd:COG2268 316 AEkqaaEAEAEAEAEAIRAKGL 337
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2854-2978 |
5.40e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 5.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2854 VQQLVLEKEQALADLNsvekSLADLFRRYEKMKEVLEGFRKNEEVLKRC---AQEYLS-RVKKEEQRYQALKVH---AEE 2926
Cdd:COG4913 213 VREYMLEEPDTFEAAD----ALVEHFDDLERAHEALEDAREQIELLEPIrelAERYAAaRERLAELEYLRAALRlwfAQR 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1370456155 2927 KLDRANAEIAQVRgkaqqeqaahqASLRKEQLRVDALERTLEQKNKEIEELT 2978
Cdd:COG4913 289 RLELLEAELEELR-----------AELARLEAELERLEARLDALREELDELE 329
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
2789-2988 |
5.54e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 5.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2789 DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektiaqmIEDEQREKSVSHQTVQQLVLEKEQALA-- 2866
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED--------LEKEIKRLELEIEEVEARIKKYEEQLGnv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2867 ----DLNSVEKSLADLfrryEKMKEVLEgfrknEEVLkrcaqeylsrvkkeeqryqalkvHAEEKLDRANAEIAQVRGKA 2942
Cdd:COG1579 86 rnnkEYEALQKEIESL----KRRISDLE-----DEIL-----------------------ELMERIEELEEELAELEAEL 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1370456155 2943 QQeqaahqaslRKEQLR--VDALERTLEQKNKEIEELTKICDELIAKM 2988
Cdd:COG1579 134 AE---------LEAELEekKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
2790-2984 |
6.15e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 6.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2790 LDSALQIARAEIitkeREVSEW-KDKYEESRREVMEMRKIVAEYEKtiAQMIEDEQREKSVSHQTVQQLVLEKEQALADL 2868
Cdd:COG3206 162 LEQNLELRREEA----RKALEFlEEQLPELRKELEEAEAALEEFRQ--KNGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2869 NSVEKSLADLFRRYEKMKEVLEGFRKNEEVlkrcaQEYLSRVKKEEQRYQALKVHAEEK---LDRANAEIAQVRGKAQQE 2945
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVI-----QQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE 310
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1370456155 2946 QAAHQASLRKE----QLRVDALERTLEQKNKEIEELTKICDEL 2984
Cdd:COG3206 311 AQRILASLEAElealQAREASLQAQLAQLEARLAELPELEAEL 353
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
2776-2985 |
7.58e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 7.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2776 EVEKpagllfQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR--EKSVSHQT 2853
Cdd:PRK04778 307 YVEK------NSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERiaEQEIAYSE 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2854 VQqlvlekeqalADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLS-------RVKKEE-----QRYQALK 2921
Cdd:PRK04778 381 LQ----------EELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNklheikrYLEKSNlpglpEDYLEMF 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370456155 2922 VHAEEKLDRANAEIAQVRgkaqqeqaahqaslrkeqLRVDALERTLEQKNKEIEELTKICDELI 2985
Cdd:PRK04778 451 FEVSDEIEALAEELEEKP------------------INMEAVNRLLEEATEDVETLEEETEELV 496
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
2786-2989 |
7.95e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 7.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2786 QQPDLDSalQIARAEIITK-EREVSEWKDKYEESRREVMEMRKIVAEYEKTI------AQMIEDEQREKSVSHQTVQQLV 2858
Cdd:PRK02224 490 EVEEVEE--RLERAEDLVEaEDRIERLEERREDLEELIAERRETIEEKRERAeelrerAAELEAEAEEKREAAAEAEEEA 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2859 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKvhaeEKLDRanaeIAQV 2938
Cdd:PRK02224 568 EEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA----EKRER----KREL 639
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1370456155 2939 RGKAQQEqaahqaslRKEQLRVDA--LERTLEQKNKEIEELTKICDELIAKMG 2989
Cdd:PRK02224 640 EAEFDEA--------RIEEAREDKerAEEYLEQVEEKLDELREERDDLQAEIG 684
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2802-2990 |
8.31e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 8.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2802 ITKEREVSEWKDKYE----ESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT-VQQLVLEKEQALADLNSVEKSLA 2876
Cdd:TIGR00618 245 LTQKREAQEEQLKKQqllkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370456155 2877 DLFRRY----------EKMKEVLEGFRKNEEVLKRCAQ------EYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQ 2937
Cdd:TIGR00618 325 KLLMKRaahvkqqssiEEQRRLLQTLHSQEIHIRDAHEvatsirEISCQQHTLTQHIHTLqqqKTTLTQKLQSLCKELDI 404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1370456155 2938 VRgKAQQEQAAHQASLRKEQLRVDALERT--LEQKNKEIEELTKICDELIAKMGK 2990
Cdd:TIGR00618 405 LQ-REQATIDTRTSAFRDLQGQLAHAKKQqeLQQRYAELCAAAITCTAQCEKLEK 458
|
|
| |
