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Conserved domains on  [gi|1370462617|ref|XP_024304893|]
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splicing factor, suppressor of white-apricot homolog isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 83-136 3.20e-16

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 73.39  E-value: 3.20e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617   83 HAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKE 136
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 331-382 5.48e-15

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


:

Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 69.92  E-value: 5.48e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617  331 QPVIDKLAEYVARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQ 382
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERerNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
rpsP super family cl36390
30S ribosomal protein S16; Provisional
 511-592 6.93e-03

30S ribosomal protein S16; Provisional


The actual alignment was detected with superfamily member PRK14521:

Pssm-ID: 237744 [Multi-domain]  Cd Length: 186  Bit Score: 38.60  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462617 511 KKPQLTQEELEAKQA--KQKLEDRLAAAArEKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVE 588
Cdd:PRK14521   90 AKGAFTEAQAEAKFEawKEEKEGKVNAKK-DKLSKAKKAAKKAALEAEKKVNEARAEAVAEKKAAEAAAVAAEEAAAAEE 168


                  ....
gi 1370462617 589 ESST 592
Cdd:PRK14521  169 EEAE 172
 
Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 83-136 3.20e-16

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 73.39  E-value: 3.20e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617   83 HAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKE 136
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 84-128 4.32e-15

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 69.85  E-value: 4.32e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370462617  84 AIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLR-FDHYLNPYYK 128
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFdPDDPLHAYYR 46
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 331-382 5.48e-15

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 69.92  E-value: 5.48e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617  331 QPVIDKLAEYVARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQ 382
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERerNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 333-376 3.44e-12

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 61.77  E-value: 3.44e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370462617 333 VIDKLAEYVARNGLKFETSVRAK--NDQRFEFL-QPWHQYNAYYEFK 376
Cdd:pfam01805   2 IIKKTAQFVARNGPEFEALLMEReeRNPQFDFLfDPDDPLHAYYRWK 48
rpsP PRK14521
30S ribosomal protein S16; Provisional
 511-592 6.93e-03

30S ribosomal protein S16; Provisional


Pssm-ID: 237744 [Multi-domain]  Cd Length: 186  Bit Score: 38.60  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462617 511 KKPQLTQEELEAKQA--KQKLEDRLAAAArEKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVE 588
Cdd:PRK14521   90 AKGAFTEAQAEAKFEawKEEKEGKVNAKK-DKLSKAKKAAKKAALEAEKKVNEARAEAVAEKKAAEAAAVAAEEAAAAEE 168


                  ....
gi 1370462617 589 ESST 592
Cdd:PRK14521  169 EEAE 172
 
Name Accession Description Interval E-value
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 83-136 3.20e-16

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 73.39  E-value: 3.20e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617   83 HAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKE 136
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERERNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 84-128 4.32e-15

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 69.85  E-value: 4.32e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370462617  84 AIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLR-FDHYLNPYYK 128
Cdd:pfam01805   1 DIIKKTAQFVARNGPEFEALLMEREERNPQFDFLFdPDDPLHAYYR 46
SWAP smart00648
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ...
 331-382 5.48e-15

Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes


Pssm-ID: 197818 [Multi-domain]  Cd Length: 54  Bit Score: 69.92  E-value: 5.48e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370462617  331 QPVIDKLAEYVARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQ 382
Cdd:smart00648   1 LDIIDKTAQFVARNGPEFEAKLMERerNNPQFDFLKPNDPYHAYYRKKLAEYRQ 54
Surp pfam01805
Surp module; This domain is also known as the SWAP domain. SWAP stands for ...
 333-376 3.44e-12

Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding.


Pssm-ID: 460339 [Multi-domain]  Cd Length: 52  Bit Score: 61.77  E-value: 3.44e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1370462617 333 VIDKLAEYVARNGLKFETSVRAK--NDQRFEFL-QPWHQYNAYYEFK 376
Cdd:pfam01805   2 IIKKTAQFVARNGPEFEALLMEReeRNPQFDFLfDPDDPLHAYYRWK 48
rpsP PRK14521
30S ribosomal protein S16; Provisional
 511-592 6.93e-03

30S ribosomal protein S16; Provisional


Pssm-ID: 237744 [Multi-domain]  Cd Length: 186  Bit Score: 38.60  E-value: 6.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370462617 511 KKPQLTQEELEAKQA--KQKLEDRLAAAArEKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVE 588
Cdd:PRK14521   90 AKGAFTEAQAEAKFEawKEEKEGKVNAKK-DKLSKAKKAAKKAALEAEKKVNEARAEAVAEKKAAEAAAVAAEEAAAAEE 168


                  ....
gi 1370462617 589 ESST 592
Cdd:PRK14521  169 EEAE 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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