|
Name |
Accession |
Description |
Interval |
E-value |
| TBC |
smart00164 |
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and ... |
71-279 |
2.10e-83 |
|
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; Widespread domain present in Gyp6 and Gyp7, thereby giving rise to the notion that it performs a GTP-activator activity on Rab-like GTPases.
Pssm-ID: 214540 [Multi-domain] Cd Length: 216 Bit Score: 265.32 E-value: 2.10e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 71 VHKGIPHHFRAIVWQLLCSAQSMPI---KDQYSELLKMTSPCEKL----IRRDIARTYPEHNFFKEKDSLGQEVLFNVMK 143
Cdd:smart00164 1 VRKGVPPSLRGVVWKLLLNAQPMDTsadKDLYSRLLKETAPDDKSivhqIEKDLRRTFPEHSFFQDKEGPGQESLRRVLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 144 AYSLVDREVGYCQGSAFIVGLLLMQMP-EEEAFCVFVKLMQDYRLReLFKPSMAELGLCMYQFECMIQEHLPELFVHFQS 222
Cdd:smart00164 81 AYALYNPEVGYCQGMNFLAAPLLLVMEdEEDAFWCLVKLMERYGPN-FYLPDMSGLQLDLLQLDRLVKEYDPDLYKHLKD 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454477 223 QSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELM 279
Cdd:smart00164 160 LGITPSLYALRWFLTLFARELPLEIVLRIWDVLFAEGSDFLFRVALALLKLHRDVLL 216
|
|
| RabGAP-TBC |
pfam00566 |
Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are ... |
111-279 |
1.45e-55 |
|
Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, implies that these domains are GTPase activator proteins of Rab-like small GTPases.
Pssm-ID: 459855 Cd Length: 178 Bit Score: 189.00 E-value: 1.45e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 111 KLIRRDIARTYPEHNFFKEKDslGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQ-MPEEEAFCVFVKLMQDYRLRE 189
Cdd:pfam00566 10 EQIEKDVPRTFPHSFFFDNGP--GQNSLRRILKAYSIYNPDVGYCQGMNFIAAPLLLVyLDEEDAFWCFVSLLENYLLRD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 190 LFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIV-FRVGL 268
Cdd:pfam00566 88 FYTPDFPGLKRDLYVFEELLKKKLPKLYKHLKELGLDPDLFASQWFLTLFAREFPLSTVLRIWDYFFLEGEKFVlFRVAL 167
|
170
....*....|.
gi 1370454477 269 ALLQMNQAELM 279
Cdd:pfam00566 168 AILKRFREELL 178
|
|
| COG5210 |
COG5210 |
GTPase-activating protein [General function prediction only]; |
42-288 |
9.55e-44 |
|
GTPase-activating protein [General function prediction only];
Pssm-ID: 227535 [Multi-domain] Cd Length: 496 Bit Score: 165.75 E-value: 9.55e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 42 EEDSWILWGRIVN-EWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLcsAQSMPIKDQ----YSELLKM-------TSPC 109
Cdd:COG5210 179 ELAADKLWISYLDpNPLSFLPVQLSKLRELIRKGIPNELRGDVWEFL--LGIGFDLDKnpglYERLLNLhreakipTQEI 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 110 EKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEE-AFCVFVKLMQDYRLR 188
Cdd:COG5210 257 ISQIEKDLSRTFPDNSLFQTEISIRAENLRRVLKAYSLYNPEVGYVQGMNFLAAPLLLVLESEEqAFWCLVKLLKNYGLP 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 189 ELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGL 268
Cdd:COG5210 337 GYFLKNLSGLHRDLKVLDDLVEELDPELYEHLLREGVVLLMFAFRWFLTLFVREFPLEYALRIWDCLFLEGSSMLFQLAL 416
|
250 260
....*....|....*....|
gi 1370454477 269 ALLQMNQAELMQLDMEGMLQ 288
Cdd:COG5210 417 AILKLLRDKLLKLDSDELLD 436
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
317-636 |
7.75e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 7.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQS 396
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 397 DEASAKLEQAENTIRKLQHQQQwhkcssnynedfvlQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLpdENNIA 476
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELA--------------EAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL--AAQLE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 477 RLQEELIAVKLREAEAIMGLKELRQQVKDLEEhwqrhlarttgrwkdppkknAMNELQDELMTIRLREAETQAEIREIKQ 556
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEE--------------------EEEEEEEALEEAAEEEAELEEEEEALLE 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 557 RMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELR 636
Cdd:COG1196 464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA 543
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
335-648 |
7.05e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.32 E-value: 7.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 335 EEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQvtraqeaEENYLIKRELATIKQQSDEASAKLEQAENTIRKLQ 414
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELE-------EELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 415 HQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLpdENNIARLQEELIAVKLREAEAIM 494
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL--REALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 495 GLKELRQQVKDleehWQRHLARTTGRWKDppKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRR 574
Cdd:TIGR02168 825 RLESLERRIAA----TERRLEDLEEQIEE--LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 575 AEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECK---NKEEVMAVRLREADSIAA--------VAELRQHIAELE 643
Cdd:TIGR02168 899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEYSLTLEEAEAlenkieddEEEARRRLKRLE 978
|
....*
gi 1370454477 644 IQKEE 648
Cdd:TIGR02168 979 NKIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
313-685 |
1.85e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 1.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 313 KYNSKK---MKKLEKeyttikTKEMEEQVEIkrLRTEnrlLKQRIETLEKEsaslADRLIQGQVTRAQEAE-ENYLIKRE 388
Cdd:COG1196 169 KYKERKeeaERKLEA------TEENLERLED--ILGE---LERQLEPLERQ----AEKAERYRELKEELKElEAELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 389 LATIKQQSDEASAKLEQAENTIRKLQHQQQwhkcssnynedfvlQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNS 468
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELA--------------ELEAELEELRLELEELELELEEAQAEEYELLAELAR 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 469 LpdENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEhwqrhlarttgrwkdppkknAMNELQDELMTIRLREAETQ 548
Cdd:COG1196 300 L--EQDIARLEERRRELEERLEELEEELAELEEELEELEE--------------------ELEELEEELEEAEEELEEAE 357
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 549 AEIREIKQRmmemetqnqinsnhLRRAEQEVISLQEKvqyLSAQNKGLLTQLSEAKRKQAEIEckNKEEVMAVRLREADS 628
Cdd:COG1196 358 AELAEAEEA--------------LLEAEAELAEAEEE---LEELAEELLEALRAAAELAAQLE--ELEEAEEALLERLER 418
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1370454477 629 I-AAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHEGELGREGR 685
Cdd:COG1196 419 LeEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
363-604 |
5.35e-10 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 63.11 E-value: 5.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 363 SLADRLIQGQVTRAQEAEENYL--IKRELATIKQQSDEASAKLE--QAENTIRKLQHQQQwhkcssnYNEDFVLQLEKEL 438
Cdd:COG3206 156 ALAEAYLEQNLELRREEARKALefLEEQLPELRKELEEAEAALEefRQKNGLVDLSEEAK-------LLLQQLSELESQL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 439 VQARLSEAESQCALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGL-------KELRQQVKDLEEHWQ 511
Cdd:COG3206 229 AEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYtpnhpdvIALRAQIAALRAQLQ 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 512 RHLARttgrwkdppkknAMNELQDELMTIRLREAETQAEIREIKQRMMEmetqnqinsnhLRRAEQEVISLQEKVQYLSA 591
Cdd:COG3206 309 QEAQR------------ILASLEAELEALQAREASLQAQLAQLEARLAE-----------LPELEAELRRLEREVEVARE 365
|
250
....*....|...
gi 1370454477 592 QNKGLLTQLSEAK 604
Cdd:COG3206 366 LYESLLQRLEEAR 378
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
317-673 |
8.74e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.77 E-value: 8.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEY-TTIKTKEMEEQVEIKRLRtenrLLKQRIETLEKESASLadrliQGQVTRAQEAEENylIKRELATIKQQ 395
Cdd:TIGR02168 200 RQLKSLERQAeKAERYKELKAELRELELA----LLVLRLEELREELEEL-----QEELKEAEEELEE--LTAELQELEEK 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 396 SDEASAKLEQAENTIRKLQHQQQwhkcssnynedfvlqlekeLVQARLSEAESQcalKEMQDkvldiEKRNNSlpdENNI 475
Cdd:TIGR02168 269 LEELRLEVSELEEEIEELQKELY-------------------ALANEISRLEQQ---KQILR-----ERLANL---ERQL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 476 ARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRhlarttgrwkdppKKNAMNELQDELMTIRLREAETQAEIREIK 555
Cdd:TIGR02168 319 EELEAQLEELESKLDELAEELAELEEKLEELKEELES-------------LEAELEELEAELEELESRLEELEEQLETLR 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 556 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMA-VRLREADSIAAVAE 634
Cdd:TIGR02168 386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEeLQEELERLEEALEE 465
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1370454477 635 LRQHIAELE--IQKEEGKLQGQLNKSDSNQYIGELKDQIAE 673
Cdd:TIGR02168 466 LREELEEAEqaLDAAERELAQLQARLDSLERLQENLEGFSE 506
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
463-677 |
1.66e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.53 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 463 EKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEhwQRHLARTTGRWKDPPKKNAMNELQDELMTIRL 542
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--ELEQLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 543 RE---AETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIecknKEEVM 619
Cdd:TIGR02168 745 LEeriAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL----NEEAA 820
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1370454477 620 AVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNksdsNQYIGELKDQIAELNHE 677
Cdd:TIGR02168 821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESL----AAEIEELEELIEELESE 874
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
311-675 |
3.74e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 57.36 E-value: 3.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 311 QVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELA 390
Cdd:PRK02224 343 EAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERD 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 391 TIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEdfvlqLEKELVQARLSEAESQCA-----LKEMQDKVLDIEKR 465
Cdd:PRK02224 423 ELREREAELEATLRTARERVEEAEALLEAGKCPECGQP-----VEGSPHVETIEEDRERVEeleaeLEDLEEEVEEVEER 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 466 NNSLPD----ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGrwkdppKKNAMNELQDELMTIR 541
Cdd:PRK02224 498 LERAEDlveaEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEE------KREAAAEAEEEAEEAR 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 542 LREAETQAEIREIKQRMMEMETQNQINSNhLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEevmav 621
Cdd:PRK02224 572 EEVAELNSKLAELKERIESLERIRTLLAA-IADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDE----- 645
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454477 622 rlreadsiAAVAELRQHIAELE--IQKEEGKLQGQLNKSDSNQ-YIGELKDQIAELN 675
Cdd:PRK02224 646 --------ARIEEAREDKERAEeyLEQVEEKLDELREERDDLQaEIGAVENELEELE 694
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
316-618 |
1.06e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 316 SKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQ 395
Cdd:TIGR02169 680 RERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 396 SDEASAKLEQAENTIRKLQHQqqwhkcssnynedfVLQLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLPDENNi 475
Cdd:TIGR02169 760 LKELEARIEELEEDLHKLEEA--------------LNDLEARLSHSRIPEIQAE--LSKLEEEVSRIEARLREIEQKLN- 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 476 ARLQEELIAVKLREaeaimglkELRQQVKDLEEhwqrhlarttgrwkdppkKNAMNELQDELMTIRLRE-----AETQAE 550
Cdd:TIGR02169 823 RLTLEKEYLEKEIQ--------ELQEQRIDLKE------------------QIKSIEKEIENLNGKKEEleeelEELEAA 876
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370454477 551 IREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEV 618
Cdd:TIGR02169 877 LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
317-635 |
1.07e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADrliqgqvtraqeaeenylikrELATIKQQS 396
Cdd:TIGR02168 274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA---------------------QLEELESKL 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 397 DEASAKLEQAENTIrklqhqqqwhkcssnynedFVLQLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLPDENNIA 476
Cdd:TIGR02168 333 DELAEELAELEEKL-------------------EELKEELESLEAELEELEAE--LEELESRLEELEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 477 RLQEELIAVKLREAEAimglkelrqQVKDLEEHWQRHLARTTGRWKDpPKKNAMNELQDELMTIRLREAETQAEIREIKQ 556
Cdd:TIGR02168 392 ELQIASLNNEIERLEA---------RLERLEDRRERLQQEIEELLKK-LEEAELKELQAELEELEEELEELQEELERLEE 461
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370454477 557 RMMEMETQnqinsnhLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIecknkEEVMAVRLREADSIAAVAEL 635
Cdd:TIGR02168 462 ALEELREE-------LEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGV-----KALLKNQSGLSGILGVLSEL 528
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
304-679 |
1.49e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.53 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 304 KLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASL--ADRLIQG--QVTRAQEA 379
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKkkADEAKKKaeEKKKADEA 1436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 380 EENYLIKRELATIKQQSDEAsaklEQAENTIRKLQHQQQWHkcssnynedfvlQLEKELVQARLSEaESQCALKEMQDKV 459
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEA----KKAEEAKKKAEEAKKAD------------EAKKKAEEAKKAD-EAKKKAEEAKKKA 1499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 460 LDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELR--QQVKDLEEHWQRHLARTTGRWKDPPKKNAMNElqDEL 537
Cdd:PTZ00121 1500 DEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEE--DKN 1577
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 538 MTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEE 617
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454477 618 VMAVRlreADSIAAVAELRQHIAElEIQKEE----GKLQGQLNKSDSNQYIGELKDQIAELNHEGE 679
Cdd:PTZ00121 1658 ENKIK---AAEEAKKAEEDKKKAE-EAKKAEedekKAAEALKKEAEEAKKAEELKKKEAEEKKKAE 1719
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
321-652 |
3.84e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.91 E-value: 3.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 321 KLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQ--EAEENYLIKR---ELATIKQQ 395
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGREltEEHRKELLEEytaELKRIEKE 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 396 SDEASAKLEQAENTIRKLQHQQQWHKCSSNYNE--DFVLQLEKELVQARLSEAESQCA-LKEMQDKVLDIEKRNNSLPDE 472
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEELEKKAEeYEKLKEKLIKLKGEIKSLKKE 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 473 -NNIARLQEELIAV--KLREAEAIMG-------------LKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDE 536
Cdd:PRK03918 548 lEKLEELKKKLAELekKLDELEEELAellkeleelgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEE 627
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 537 LMTIRLREAETQAEIREIKQRMMEMEtqNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEcKNKE 616
Cdd:PRK03918 628 LDKAFEELAETEKRLEELRKELEELE--KKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLK-EELE 704
|
330 340 350
....*....|....*....|....*....|....*....
gi 1370454477 617 EVMAVRLREAD---SIAAVAELRQHIAELEIQKEEGKLQ 652
Cdd:PRK03918 705 EREKAKKELEKlekALERVEELREKVKKYKALLKERALS 743
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
272-646 |
5.57e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.58 E-value: 5.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 272 QMNQAELMQLDMEGMLQHFQKVIphqfdgvpdkliqaayqVKYNSKKMKKLEKE--YTTIKTKEMEEQVE--IKRLRTEN 347
Cdd:pfam15921 171 QIEQLRKMMLSHEGVLQEIRSIL-----------------VDFEEASGKKIYEHdsMSTMHFRSLGSAISkiLRELDTEI 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 348 RLLKQRI-------ETLEKESASLADRLIQGQVTRAQEaeenyLIKRELATIKQQSDEASAKLEQAeNTIRKlqhqqqwh 420
Cdd:pfam15921 234 SYLKGRIfpvedqlEALKSESQNKIELLLQQHQDRIEQ-----LISEHEVEITGLTEKASSARSQA-NSIQS-------- 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 421 kcssnynedfvlQLEKELVQARLSEAESQCALKEMQDKV--LDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKE 498
Cdd:pfam15921 300 ------------QLEIIQEQARNQNSMYMRQLSDLESTVsqLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 499 LRQQVKDLEEHWQRHLArttgrwkdppkknamnelqdelmTIRLREAETQAEiREIKQRMMEMETQNQINSNHLRRaeqE 578
Cdd:pfam15921 368 FSQESGNLDDQLQKLLA-----------------------DLHKREKELSLE-KEQNKRLWDRDTGNSITIDHLRR---E 420
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370454477 579 VISLQEKVQYLSAQNKGLLTQLS-EAKRKQAEIECKNKEevmavrLREADSIAAVAE-----LRQHIAELEIQK 646
Cdd:pfam15921 421 LDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNES------LEKVSSLTAQLEstkemLRKVVEELTAKK 488
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
335-557 |
8.12e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 8.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 335 EEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEaeenylikrELATIKQQSDEASAKLEQAENTIRKLQ 414
Cdd:COG4913 259 ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA---------ELARLEAELERLEARLDALREELDELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 415 HQQQwhkcSSNYNEdfVLQLEKELVQARLSEAESqcalkemqdkvldiekrnnslpdENNIARLQEELIAVKLREAEAIM 494
Cdd:COG4913 330 AQIR----GNGGDR--LEQLEREIERLERELEER-----------------------ERRRARLEALLAALGLPLPASAE 380
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370454477 495 GLKELRQQVKDLEEHWQRHLARTTgrwkdppkkNAMNELQDELMTIRLREAETQAEIREIKQR 557
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALE---------EALAEAEAALRDLRRELRELEAEIASLERR 434
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
317-677 |
8.97e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.46 E-value: 8.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKEsASLADRLIQGQVTRAQEAEENYLIKRELATIKQQS 396
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELR 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 397 dEASAKLEQAENTIRKLQHQ-QQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDENNI 475
Cdd:COG4717 160 -ELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 476 ARLQEEL--IAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTG-----RWKDPPKKNAMNELQDELMTIRLREAETQ 548
Cdd:COG4717 239 AALEERLkeARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGllallFLLLAREKASLGKEAEELQALPALEELEE 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 549 AEIREIKQR-MMEMETQNQINSNHLRRAEQevisLQEKVQYLSAQNKGLLTQLSEAKRKQ--AEIECKNKEEVMAVRLRE 625
Cdd:COG4717 319 EELEELLAAlGLPPDLSPEELLELLDRIEE----LQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAALEQA 394
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1370454477 626 ADSIAAVAELRQHIAELE-IQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHE 677
Cdd:COG4717 395 EEYQELKEELEELEEQLEeLLGELEELLEALDEEELEEELEELEEELEELEEE 447
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
386-679 |
2.34e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 386 KRELATIKQQSDEASAKLEQAENTIRKLQHQQqwhkcssnynedfvLQLEK-ELVQARLSEAESQCALKEMQDKVLDIEK 464
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRRER--------------EKAERyQALLKEKREYEGYELLKEKEALERQKEA 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 465 RNNSLPD-ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEhwqrhlarttgrwkdppkkNAMNELQDELMTIRLR 543
Cdd:TIGR02169 242 IERQLASlEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE-------------------EEQLRVKEKIGELEAE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 544 EAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRL 623
Cdd:TIGR02169 303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370454477 624 READSIAAVAELRQHIAEL-EIQKEEGKLQGQLNK-----SDSNQYIGELKDQIAELNHEGE 679
Cdd:TIGR02169 383 TRDELKDYREKLEKLKREInELKRELDRLQEELQRlseelADLNAAIAGIEAKINELEEEKE 444
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
307-492 |
3.40e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 3.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 307 QAAYQVKYNSKK--MKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYL 384
Cdd:TIGR02169 324 LAKLEAEIDKLLaeIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 385 IKRELATIKQQSDEASAKLEQAENTIRKLQHQQqwhkcssnyNEdfvLQLEKELVQARLSEAESQcaLKEMQDKVLDIEK 464
Cdd:TIGR02169 404 LKRELDRLQEELQRLSEELADLNAAIAGIEAKI---------NE---LEEEKEDKALEIKKQEWK--LEQLAADLSKYEQ 469
|
170 180 190
....*....|....*....|....*....|
gi 1370454477 465 RNNSLpdENNIARLQEELIAV--KLREAEA 492
Cdd:TIGR02169 470 ELYDL--KEEYDRVEKELSKLqrELAEAEA 497
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
293-648 |
3.59e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.51 E-value: 3.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 293 VIPHQFDGVPDKLiqAAYQVKYNSKKMKKLEKEYTTIkTKEMEEQVEIKRLrTENRLLKQRIEtlekesasladrLIQGQ 372
Cdd:pfam17380 218 VAPKEVQGMPHTL--APYEKMERRKESFNLAEDVTTM-TPEYTVRYNGQTM-TENEFLNQLLH------------IVQHQ 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 373 VTRAQEAEENYLIKRELATIKQQSDEASAKLEQAentiRKLQH-----QQQWHKCSSNYNEDFVLQLEKELVQARLSEAE 447
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREVERR----RKLEEaekarQAEMDRQAAIYAEQERMAMERERELERIRQEE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 448 SQCALKEMQDKVLDIEkrnnsLPDENNIARLQEEliavKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKK 527
Cdd:pfam17380 358 RKRELERIRQEEIAME-----ISRMRELERLQME----RQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAE 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 528 namnelQDELMTIRLREAETQAEIREIKQRMMEMETQNQI-----NSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSE 602
Cdd:pfam17380 429 ------QEEARQREVRRLEEERAREMERVRLEEQERQQQVerlrqQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELE 502
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1370454477 603 AkRKQAEIECKNKEEVMAVRLREADSiAAVAELRQHIAELEIQKEE 648
Cdd:pfam17380 503 E-RKQAMIEEERKRKLLEKEMEERQK-AIYEEERRREAEEERRKQQ 546
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
474-689 |
4.89e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 4.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 474 NIARLQEELIavKLREAEAIMglKELRQQVKDLE---EHWQRHLArttgrwkdppKKNAMNELQDELMTIRLREAET--- 547
Cdd:COG4913 226 AADALVEHFD--DLERAHEAL--EDAREQIELLEpirELAERYAA----------ARERLAELEYLRAALRLWFAQRrle 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 548 --QAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEiECKNKEEVMAVRLRE 625
Cdd:COG4913 292 llEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELE-ERERRRARLEALLAA 370
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 626 -----ADSIAAVAELRQHIAEL--EIQKEEGKLQGQLNKSDSNQYigELKDQIAELNHEGELGREGRNVIP 689
Cdd:COG4913 371 lglplPASAEEFAALRAEAAALleALEEELEALEEALAEAEAALR--DLRRELRELEAEIASLERRKSNIP 439
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
351-557 |
5.18e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 5.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 351 KQRIETLEKESASLADRL--IQGQVTRAQEAEENYLIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQwhKCSSNYNE 428
Cdd:COG4913 609 RAKLAALEAELAELEEELaeAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELE--RLDASSDD 686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 429 dfVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRnnslpdennIARLQEELIAVKLREAEAIMGLKElrQQVKDLEE 508
Cdd:COG4913 687 --LAALEEQLEELEAELEELEEELDELKGEIGRLEKE---------LEQAEEELDELQDRLEAAEDLARL--ELRALLEE 753
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1370454477 509 HWQRHLARTTGRwkdppkkNAMNELQDELMTIRLREAETQAEIREIKQR 557
Cdd:COG4913 754 RFAAALGDAVER-------ELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
270-667 |
7.27e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.51 E-value: 7.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 270 LLQMNQAELMQLDMEGMLQHFQKVIphqfdgvpdKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEikRLRTENRL 349
Cdd:pfam07888 23 LLVVPRAELLQNRLEECLQERAELL---------QAQEAANRQREKEKERYKRDREQWERQRRELESRVA--ELKEELRQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 350 LKQRIETLE---KESASLADRLIQGQVTRAQEAEENYLIKREL----ATIKQQSDEASAKLEQAENTIRKLQHQQQwhkc 422
Cdd:pfam07888 92 SREKHEELEekyKELSASSEELSEEKDALLAQRAAHEARIRELeediKTLTQRVLERETELERMKERAKKAGAQRK---- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 423 ssnynEDfvlQLEKELVQARL--SEAESQCALKEMQD-KVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKEL 499
Cdd:pfam07888 168 -----EE---EAERKQLQAKLqqTEEELRSLSKEFQElRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEEL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 500 R--QQVKDLEEHWQRHLAR---TTGRWKDppkknamnELQDELMTIRLREAETQAEIREIKQRMMEMETQ-NQINSNHLR 573
Cdd:pfam07888 240 RslQERLNASERKVEGLGEelsSMAAQRD--------RTQAELHQARLQAAQLTLQLADASLALREGRARwAQERETLQQ 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 574 RAEQEvislQEKVQYLSAQNKGLLTQLSEAK--RKQAEIECKNKEEVMAVRLREADSiaavaELRQHIAELEI-QKEegK 650
Cdd:pfam07888 312 SAEAD----KDRIEKLSAELQRLEERLQEERmeREKLEVELGREKDCNRVQLSESRR-----ELQELKASLRVaQKE--K 380
|
410
....*....|....*..
gi 1370454477 651 LQGQLNKSDSNQYIGEL 667
Cdd:pfam07888 381 EQLQAEKQELLEYIRQL 397
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
477-682 |
9.27e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 9.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 477 RLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHlarttgRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQ 556
Cdd:TIGR02168 236 ELREELEELQEELKEAEEELEELTAELQELEEKLEEL------RLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 557 RMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEckNKEEVMAVRLREADsiAAVAELR 636
Cdd:TIGR02168 310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE--AELEELESRLEELE--EQLETLR 385
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 637 QHIAELEiqKEEGKLQGQLN-----KSDSNQYIGELKDQIAELNHEGELGR 682
Cdd:TIGR02168 386 SKVAQLE--LQIASLNNEIErlearLERLEDRRERLQQEIEELLKKLEEAE 434
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
335-685 |
1.10e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.27 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 335 EEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELA-------TIKQQSDEASAKLEQAE 407
Cdd:PRK02224 248 ERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeAVEARREELEDRDEELR 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 408 NTIRKLQHQQQWHKCSSNYNEDFVLQLE--------------KELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPD-- 471
Cdd:PRK02224 328 DRLEECRVAAQAHNEEAESLREDADDLEeraeelreeaaeleSELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdl 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 472 ---ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGR-WKDPPKKNAMNELQDELMTIRLREAET 547
Cdd:PRK02224 408 gnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQpVEGSPHVETIEEDRERVEELEAELEDL 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 548 QAEIREIKQRMMEMETqnqinsnhLRRAEQEVISLQEK----VQYLSAQNKGLltqlsEAKRKQAEIECKNKEEVMAvRL 623
Cdd:PRK02224 488 EEEVEEVEERLERAED--------LVEAEDRIERLEERredlEELIAERRETI-----EEKRERAEELRERAAELEA-EA 553
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370454477 624 READSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHEGELGREGR 685
Cdd:PRK02224 554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKR 615
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
332-685 |
1.29e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 332 KEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQE------AEENYLIKRELATIKQQSDEASAKLEQ 405
Cdd:pfam02463 177 KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEeyllylDYLKLNEERIDLLQELLRDEQEEIESS 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 406 AENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDENN----------- 474
Cdd:pfam02463 257 KQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKaekelkkekee 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 475 IARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREi 554
Cdd:pfam02463 337 IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 555 KQRMMEMETQNQInsnhlrraEQEVISLQEKVQYLSAQnkglLTQLSEAKRKQAEIECKNKEEVMAVRlREADSIAAVAE 634
Cdd:pfam02463 416 QLEDLLKEEKKEE--------LEILEEEEESIELKQGK----LTEEKEELEKQELKLLKDELELKKSE-DLLKETQLVKL 482
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 635 LRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHEGELGREGR 685
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD 533
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
346-657 |
1.55e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.80 E-value: 1.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 346 ENRL--LKQRIETLEKESASLA-------------DRLIQGQVTRAQEAEENylikRELATIKQQSDEASAKLEQAENTI 410
Cdd:PRK04863 785 EKRIeqLRAEREELAERYATLSfdvqklqrlhqafSRFIGSHLAVAFEADPE----AELRQLNRRRVELERALADHESQE 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 411 RklQHQQQWHK----CSS-NYNEDFVLQLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLPD-ENNIARLQ---EE 481
Cdd:PRK04863 861 Q--QQRSQLEQakegLSAlNRLLPRLNLLADETLADRVEEIREQ--LDEAEEAKRFVQQHGNALAQlEPIVSVLQsdpEQ 936
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 482 LIAVKLREAEAIMGLKELRQQVKDLEEHWQR--HLArttgrWKDPPKK-NAMNELQDELMTiRLREAETQAeiREIKQRM 558
Cdd:PRK04863 937 FEQLKQDYQQAQQTQRDAKQQAFALTEVVQRraHFS-----YEDAAEMlAKNSDLNEKLRQ-RLEQAEQER--TRAREQL 1008
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 559 MEMETQnqinsnhLRRAEQEVISLQEkvqylSAQNKglLTQLSEAKRKQAEI---ECKNKEEVMAVRLREADSIAAVAEL 635
Cdd:PRK04863 1009 RQAQAQ-------LAQYNQVLASLKS-----SYDAK--RQMLQELKQELQDLgvpADSGAEERARARRDELHARLSANRS 1074
|
330 340
....*....|....*....|..
gi 1370454477 636 RQHIAELEIQKEEGKLQGQLNK 657
Cdd:PRK04863 1075 RRNQLEKQLTFCEAEMDNLTKK 1096
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
399-660 |
1.69e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 399 ASAKLEQAENTIRKLQHQQQwhkcssnynedfvlQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLpdENNIARL 478
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIA--------------ELEKELAALKKEEKALLKQLAALERRIAALARRIRAL--EQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 479 QEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRhlarttgrwkdppkknamNELQDELMTIRLREAETQAEIREIKQRM 558
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALYR------------------LGRQPPLALLLSPEDFLDAVRRLQYLKY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 559 MEMETQNQINSnhLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQH 638
Cdd:COG4942 144 LAPARREQAEE--LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
250 260
....*....|....*....|....
gi 1370454477 639 IAELE--IQKEEGKLQGQLNKSDS 660
Cdd:COG4942 222 AEELEalIARLEAEAAAAAERTPA 245
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
320-674 |
2.07e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.39 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 320 KKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEEnyLIKRELATIKQQSDEA 399
Cdd:COG1196 382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA--LEEAAEEEAELEEEEE 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 400 SAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEK--------------- 464
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGavavligveaayeaa 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 465 ---------RNNSLPDENNIARLQEELIAVKLREAE-----AIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAM 530
Cdd:COG1196 540 leaalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATflpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 531 NELQDELM-------------TIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL 597
Cdd:COG1196 620 DTLLGRTLvaarleaalrravTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 598 TQLSEAKRKQAEIE---CKNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAEL 674
Cdd:COG1196 700 LAEEEEERELAEAEeerLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
332-638 |
2.29e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.89 E-value: 2.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 332 KEMEEQV---EIKRLRTENRLLKQRIETLEKE----SASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEASAkle 404
Cdd:pfam10174 459 REREDRErleELESLKKENKDLKEKVSALQPEltekESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSK--- 535
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 405 qAENTIRKLQHQQQWHKCSSNYNeDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSlpDENNIARLqEELIA 484
Cdd:pfam10174 536 -LENQLKKAHNAEEAVRTNPEIN-DRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKND--KDKKIAEL-ESLTL 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 485 VKLREAEAIMGLKELRQQVKDLEEHWQRHLARttgRWKDPPKKNAMNELQDELMTIRLReaeTQAEIREIKQRMMEMETQ 564
Cdd:pfam10174 611 RQMKEQNKKVANIKHGQQEMKKKGAQLLEEAR---RREDNLADNSQQLQLEELMGALEK---TRQELDATKARLSSTQQS 684
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 565 NQINSNHL------RRAEQEVIsLQEKVQYLSA------QNKGLLtQLSEAKRKqaeiecKNKEEVMAVRlREADSIaaV 632
Cdd:pfam10174 685 LAEKDGHLtnlraeRRKQLEEI-LEMKQEALLAaisekdANIALL-ELSSSKKK------KTQEEVMALK-REKDRL--V 753
|
....*.
gi 1370454477 633 AELRQH 638
Cdd:pfam10174 754 HQLKQQ 759
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
307-678 |
3.88e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 307 QAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRL--------IQGQVTRAQE 378
Cdd:PRK04863 276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLnlvqtalrQQEKIERYQA 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 379 AEENYLIKRE-----LATIKQQSDEASAKLEQAENTIRKLQHQQqwhkcsSNYNEDFVLQLEKEL-----VQArLSEAES 448
Cdd:PRK04863 356 DLEELEERLEeqnevVEEADEQQEENEARAEAAEEEVDELKSQL------ADYQQALDVQQTRAIqyqqaVQA-LERAKQ 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 449 QCAL-------------------KEMQDKVLDIEKRNNSLPDenniARLQEELIAVKLREAEAIMGLKELRQQVKDLEEH 509
Cdd:PRK04863 429 LCGLpdltadnaedwleefqakeQEATEELLSLEQKLSVAQA----AHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRR 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 510 W--QRHLARTTgrwkdPPKKNAMNELQDELMtirlREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQ 587
Cdd:PRK04863 505 LreQRHLAEQL-----QQLRMRLSELEQRLR----QQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVS 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 588 YLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMA----VRLRE------ADSiAAVAELRQHIAELEIQKeegklqgQLNK 657
Cdd:PRK04863 576 EARERRMALRQQLEQLQARIQRLAARAPAWLAAqdalARLREqsgeefEDS-QDVTEYMQQLLEREREL-------TVER 647
|
410 420
....*....|....*....|.
gi 1370454477 658 SDSNQYIGELKDQIAELNHEG 678
Cdd:PRK04863 648 DELAARKQALDEEIERLSQPG 668
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
304-643 |
5.36e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.85 E-value: 5.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 304 KLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENY 383
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 384 LIKRELATIKQQSD---EASAKLEQAENTIRKLQHQQQ-------------WHKCSSNYNEDFVLQLEKELVQARLSEAE 447
Cdd:COG1196 481 ELLEELAEAAARLLlllEAEADYEGFLEGVKAALLLAGlrglagavavligVEAAYEAALEAALAAALQNIVVEDDEVAA 560
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 448 SQCA-LKEMQDK-----VLDIEKRNNSLPDENNIARLQEE--LIAVKLREAEA----IMGLKELRQQVKDLEEHWQRHLA 515
Cdd:COG1196 561 AAIEyLKAAKAGratflPLDKIRARAALAAALARGAIGAAvdLVASDLREADAryyvLGDTLLGRTLVAARLEAALRRAV 640
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 516 RTTGRWKDppKKNAMNELQDELMTIRLR-------EAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQY 588
Cdd:COG1196 641 TLAGRLRE--VTLEGEGGSAGGSLTGGSrrellaaLLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1370454477 589 LSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQHIAELE 643
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
307-570 |
7.63e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.59 E-value: 7.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 307 QAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQgqvtraqeaeenylIK 386
Cdd:TIGR02168 793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES--------------LA 858
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 387 RELATIKQQSDEASAKLEQAENtiRKLQHQQQWHKCSSNYNEdfvlqLEKELVQARLSEAESQCALKEMQDKVLDIEKRN 466
Cdd:TIGR02168 859 AEIEELEELIEELESELEALLN--ERASLEEALALLRSELEE-----LSEELRELESKRSELRRELEELREKLAQLELRL 931
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 467 NSLpdENNIARLQEELIAVKLREAEAIMGLKELrqqVKDLEEHWQRHLARTTGRWKD--PPKKNAMNELQDElmTIRLRE 544
Cdd:TIGR02168 932 EGL--EVRIDNLQERLSEEYSLTLEEAEALENK---IEDDEEEARRRLKRLENKIKElgPVNLAAIEEYEEL--KERYDF 1004
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1370454477 545 AETQAE------------IREIKQRMME--METQNQINSN 570
Cdd:TIGR02168 1005 LTAQKEdlteaketleeaIEEIDREARErfKDTFDQVNEN 1044
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
302-508 |
8.79e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 8.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 302 PDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRL----IQGQVTRAQ 377
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELaeleKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 378 EAEENYLIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQD 457
Cdd:COG4942 99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 458 KVLDIEKRNNSLpdENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEE 508
Cdd:COG4942 179 LLAELEEERAAL--EALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
446-639 |
9.82e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 9.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 446 AESQCALKEMQD---KVLDIEKRNNSLPDEnnIARLQEELIAVKLREAEAIMGLKELRQQVKDLE---EHWQRHLARTTG 519
Cdd:COG1579 3 PEDLRALLDLQEldsELDRLEHRLKELPAE--LAELEDELAALEARLEAAKTELEDLEKEIKRLEleiEEVEARIKKYEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 520 RWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEvisLQEKVQYLSAQNKGLLTQ 599
Cdd:COG1579 81 QLGNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE---LEEKKAELDEELAELEAE 157
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1370454477 600 LSEAKRKQAEIECKNKEEVMAV--RLREADSIAAVAELRQHI 639
Cdd:COG1579 158 LEELEAEREELAAKIPPELLALyeRIRKRKNGLAVVPVEGGA 199
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
303-677 |
1.03e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.78 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 303 DKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLL-------KQRIETLEKESASLAdrliqgqvtr 375
Cdd:TIGR04523 61 KNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKInseikndKEQKNKLEVELNKLE---------- 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 376 aQEAEENyliKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCAL--- 452
Cdd:TIGR04523 131 -KQKKEN---KKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLsnl 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 453 -------KEMQDKVLDIEKRNNSLpdENNIARLQEELIAVKL---REAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWK 522
Cdd:TIGR04523 207 kkkiqknKSLESQISELKKQNNQL--KDNIEKKQQEINEKTTeisNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIK 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 523 DppKKNAMNELQDELMTIRLREA-----ETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLL 597
Cdd:TIGR04523 285 E--LEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 598 TQLSEaKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHE 677
Cdd:TIGR04523 363 RELEE-KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSE 441
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
350-567 |
1.09e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 350 LKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNED 429
Cdd:COG4717 51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 430 FvlqLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLPD-ENNIARLQEELiaVKLREAEAIMGLKELRQQVKDLEE 508
Cdd:COG4717 131 Y---QELEALEAELAELPER--LEELEERLEELRELEEELEElEAELAELQEEL--EELLEQLSLATEEELQDLAEELEE 203
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1370454477 509 HWQRhlarttgrwkdppkknaMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQI 567
Cdd:COG4717 204 LQQR-----------------LAELEEELEEAQEELEELEEELEQLENELEAAALEERL 245
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
496-687 |
1.27e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 496 LKELRQQVKDLEEHWQRHlarttgrwkdppkknamNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNH--LR 573
Cdd:COG4717 73 LKELEEELKEAEEKEEEY-----------------AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYqeLE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 574 RAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEevmAVRLREADSIAAVAELRQHIAELE-IQKEEGKLQ 652
Cdd:COG4717 136 ALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEE---LEELLEQLSLATEEELQDLAEELEeLQQRLAELE 212
|
170 180 190
....*....|....*....|....*....|....*
gi 1370454477 653 GQLNKSDsnQYIGELKDQIAELNHEGELGREGRNV 687
Cdd:COG4717 213 EELEEAQ--EELEELEEELEQLENELEAAALEERL 245
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
317-648 |
1.32e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 1.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKtkemEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENY-LIKRELATIKQQ 395
Cdd:COG4717 146 ERLEELEERLEELR----ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLaELEEELEEAQEE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 396 SDEASAKLEQAENTIRKLQHQQQWHKCSSNYN-----------------------------------EDFVLQLEKELVQ 440
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLiaaallallglggsllsliltiagvlflvlgllalLFLLLAREKASLG 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 441 ARLSEAESQCALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKlreaeaimGLKELRQQVKDLEEHWQRHLARTTgr 520
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE--------ELQELLREAEELEEELQLEELEQE-- 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 521 wkdppKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQ--NQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLT 598
Cdd:COG4717 372 -----IAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEE 446
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1370454477 599 QLSEAKRKQAEIEcknkeevmaVRLREADSIAAVAELRQHIAELEIQKEE 648
Cdd:COG4717 447 ELEELREELAELE---------AELEQLEEDGELAELLQELEELKAELRE 487
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
339-508 |
1.49e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 339 EIKRLRTENRLLKQRIETLEKESASLADRLIQgqvtraqeaeenylIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQ 418
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEA--------------AKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 419 whkcSSNYNEDFV-LQLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLpdENNIARLQEELIAVKlREAEAImgLK 497
Cdd:COG1579 84 ----NVRNNKEYEaLQKEIESLKRRISDLEDE--ILELMERIEELEEELAEL--EAELAELEAELEEKK-AELDEE--LA 152
|
170
....*....|.
gi 1370454477 498 ELRQQVKDLEE 508
Cdd:COG1579 153 ELEAELEELEA 163
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
340-652 |
2.14e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.03 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 340 IKRLR--TENRLLKQRIETLEKESASLADRLiqgQVTRAQEAEenylIKRELATIKQQSDEASAKLEQAENTIRKLQHQQ 417
Cdd:PRK02224 178 VERVLsdQRGSLDQLKAQIEEKEEKDLHERL---NGLESELAE----LDEEIERYEEQREQARETRDEADEVLEEHEERR 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 418 QwhkcssnynEDFVLQLEKELVQARLSEAESQC-----ALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKL----- 487
Cdd:PRK02224 251 E---------ELETLEAEIEDLRETIAETEREReelaeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARReeled 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 488 REAEAIMGLKELRQQVKDLEEHWQRHLARTT---GRWKDppKKNAMNELQDELMTIR--LREAETQ-----AEIREIKQR 557
Cdd:PRK02224 322 RDEELRDRLEECRVAAQAHNEEAESLREDADdleERAEE--LREEAAELESELEEAReaVEDRREEieeleEEIEELRER 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 558 MMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEvmavRLREADSIAAVAELRQ 637
Cdd:PRK02224 400 FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQ----PVEGSPHVETIEEDRE 475
|
330
....*....|....*
gi 1370454477 638 HIAELEIQKEEGKLQ 652
Cdd:PRK02224 476 RVEELEAELEDLEEE 490
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
475-675 |
2.26e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 475 IARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKD---PPKKNAMNELQDE----------LMTIR 541
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvASAEREIAELEAElerldassddLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 542 LREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIEC--------- 612
Cdd:COG4913 692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAverelrenl 771
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 613 ----------KNKEEVMAVRLREA-------------DSIAAVAELRQHIAELE----IQKEEgKLQGQLNKSdSNQYIG 665
Cdd:COG4913 772 eeridalrarLNRAEEELERAMRAfnrewpaetadldADLESLPEYLALLDRLEedglPEYEE-RFKELLNEN-SIEFVA 849
|
250 260
....*....|....*....|.
gi 1370454477 666 EL-----------KDQIAELN 675
Cdd:COG4913 850 DLlsklrraireiKERIDPLN 870
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
475-689 |
2.99e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.67 E-value: 2.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 475 IARLQEELIAVKLREAEAIMGLKELRQQVKDLEehwqrhlarttgrwKDPPKKNAMNELQDElmtirLREAETQAEIREI 554
Cdd:TIGR02169 172 KEKALEELEEVEENIERLDLIIDEKRQQLERLR--------------REREKAERYQALLKE-----KREYEGYELLKEK 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 555 KqrmmEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKqaeIECKNKEEVMAVRLREADSIAAVAE 634
Cdd:TIGR02169 233 E----ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLRVKEKIGELEAEIAS 305
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1370454477 635 LRQHIAELEIQKEEgkLQGQLNKSDSNqyIGELKDQIAELnhEGELGREGRNVIP 689
Cdd:TIGR02169 306 LERSIAEKERELED--AEERLAKLEAE--IDKLLAEIEEL--EREIEEERKRRDK 354
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
311-680 |
3.00e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.57 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 311 QVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRliqGQVTRAQEAEENYLIKR--E 388
Cdd:TIGR00618 436 QQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVV---LARLLELQEEPCPLCGSciH 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 389 LATIKQQSDEASA---KLEQAENTIRKLQHQQQ--WHKCSSNYNEDFVLQLEKELVQARLSEAESQ-CALKEMQDKVLDI 462
Cdd:TIGR00618 513 PNPARQDIDNPGPltrRMQRGEQTYAQLETSEEdvYHQLTSERKQRASLKEQMQEIQQSFSILTQCdNRSKEDIPNLQNI 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 463 EKRNNSLPDENNIARLQ-EELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNEL----QDEL 537
Cdd:TIGR00618 593 TVRLQDLTEKLSEAEDMlACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHAlsirVLPK 672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 538 MTIRLREAETQAEIREIKQRMMEMETQNQINSNhLRRAEQEVISLQEKVQYLS----------AQNKGLLTQLSEAKRKQ 607
Cdd:TIGR00618 673 ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTL-LRELETHIEEYDREFNEIEnassslgsdlAAREDALNQSLKELMHQ 751
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370454477 608 AEIECKNKEEVMAVR-LREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHEGEL 680
Cdd:TIGR00618 752 ARTVLKARTEAHFNNnEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET 825
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
304-677 |
3.14e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.28 E-value: 3.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 304 KLIQAAYQVKynsKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKesasLADRLIQGQVTRAQEAEENY 383
Cdd:PRK03918 183 KFIKRTENIE---ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE----LKEEIEELEKELESLEGSKR 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 384 LIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEdFVLQLEKEL--VQARLSEAESQcaLKEMQDKVLD 461
Cdd:PRK03918 256 KLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSE-FYEEYLDELreIEKRLSRLEEE--INGIEERIKE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 462 IEKRNNSLpdeNNIARLQEELiavkLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDppkknamnELQDELMTIR 541
Cdd:PRK03918 333 LEEKEERL---EELKKKLKEL----EKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE--------KLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 542 LREAETQAEIREIKQRMMEMETQnqinsnhlrraeqevislqekvqylSAQNKGLLTQLSEAKRK----QAEIECKNKEE 617
Cdd:PRK03918 398 KAKEEIEEEISKITARIGELKKE-------------------------IKELKKAIEELKKAKGKcpvcGRELTEEHRKE 452
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 618 VMAVRLREADSIAA-VAELRQHIAELEiqKEEGKLQGQLNKSDSNQYIGELKDQIAELNHE 677
Cdd:PRK03918 453 LLEEYTAELKRIEKeLKEIEEKERKLR--KELRELEKVLKKESELIKLKELAEQLKELEEK 511
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
315-686 |
4.08e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.95 E-value: 4.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 315 NSKKMKKLEKEYTTIKTKEMEeqveikrLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELatikq 394
Cdd:pfam15921 312 NSMYMRQLSDLESTVSQLRSE-------LREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL----- 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 395 QSDEASAKLEQAENTIRKLQHQQQWHKCSSnyNEDFVLQLEKEL---------VQARLSEAESQCAlKEMQDKVLDIEKR 465
Cdd:pfam15921 380 QKLLADLHKREKELSLEKEQNKRLWDRDTG--NSITIDHLRRELddrnmevqrLEALLKAMKSECQ-GQMERQMAAIQGK 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 466 NNSLpdeNNIARLQEELIAVK--LREAeaimgLKELRQQVKDLEEHwQRHLARTTGRWKDppKKNAMNELQDELMTIRLR 543
Cdd:pfam15921 457 NESL---EKVSSLTAQLESTKemLRKV-----VEELTAKKMTLESS-ERTVSDLTASLQE--KERAIEATNAEITKLRSR 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 544 EAETQAEIREIKQRmmemetqnqinSNHLRRAEQEVISL------QEKVQYLSAQNKGLLTQLS----------EAKRKQ 607
Cdd:pfam15921 526 VDLKLQELQHLKNE-----------GDHLRNVQTECEALklqmaeKDKVIEILRQQIENMTQLVgqhgrtagamQVEKAQ 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 608 AEIECKNKE-EVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLN-------KSDSNQYIGELKDQIAELNHEGE 679
Cdd:pfam15921 595 LEKEINDRRlELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERlravkdiKQERDQLLNEVKTSRNELNSLSE 674
|
410
....*....|.
gi 1370454477 680 ----LGREGRN 686
Cdd:pfam15921 675 dyevLKRNFRN 685
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
302-561 |
5.52e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 5.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 302 PDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQvtRAQEAEE 381
Cdd:COG4913 684 SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER--FAAALGD 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 382 NYLiKRELATIKQQSDEASAKLEQAENTIRKL--QHQQQWHKCSSN------YNEDFVLQLEKeLVQARLSEAESQcaLK 453
Cdd:COG4913 762 AVE-RELRENLEERIDALRARLNRAEEELERAmrAFNREWPAETADldadleSLPEYLALLDR-LEEDGLPEYEER--FK 837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 454 EMQdkvldieKRNNslpdENNIARLQEELiavkLREAEAIMG-LKELRQQVKDLEEHWQRHLARTTGRWKDPpkknAMNE 532
Cdd:COG4913 838 ELL-------NENS----IEFVADLLSKL----RRAIREIKErIDPLNDSLKRIPFGPGRYLRLEARPRPDP----EVRE 898
|
250 260 270
....*....|....*....|....*....|...
gi 1370454477 533 LQDELMTIRLREAETQAEIREIK----QRMMEM 561
Cdd:COG4913 899 FRQELRAVTSGASLFDEELSEARfaalKRLIER 931
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
323-417 |
6.90e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 6.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 323 EKEYTTIKTKEMEEQV-----EIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEA----------EENYLIKR 387
Cdd:COG2433 400 EKEHEERELTEEEEEIrrleeQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIrkdreisrldREIERLER 479
|
90 100 110
....*....|....*....|....*....|
gi 1370454477 388 ELATIKQQSDEASAKLEQAEnTIRKLQHQQ 417
Cdd:COG2433 480 ELEEERERIEELKRKLERLK-ELWKLEHSG 508
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
317-679 |
8.24e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 42.97 E-value: 8.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTenrlLKQRIETLEKESASLADRLIQGQVTRAQEAEEnylIKRELATIKQQS 396
Cdd:PRK01156 346 SRYDDLNNQILELEGYEMDYNSYLKSIES----LKKKIEEYSKNIERMSAFISEILKIQEIDPDA---IKKELNEINVKL 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 397 DEASAKLEQAENTIRKL-QHQQQWHK-------------CSSNYNEDFVLQLEKELVQ--ARLSEA--ESQCALKEMQDK 458
Cdd:PRK01156 419 QDISSKVSSLNQRIRALrENLDELSRnmemlngqsvcpvCGTTLGEEKSNHIINHYNEkkSRLEEKirEIEIEVKDIDEK 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 459 VLDIEKR---------NNSLPDENNIARLQEELIAVKLREAEaimgLKELRQQVKDLEEHWQR-HLARTTGRWKDPPKKN 528
Cdd:PRK01156 499 IVDLKKRkeyleseeiNKSINEYNKIESARADLEDIKIKINE----LKDKHDKYEEIKNRYKSlKLEDLDSKRTSWLNAL 574
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 529 AMNELQDeLMTIRLREAETQAEIREIKQRMMEMETQ----NQINSNHLRRAEQEVISLQEKVqylsaqnkglltQLSEAK 604
Cdd:PRK01156 575 AVISLID-IETNRSRSNEIKKQLNDLESRLQEIEIGfpddKSYIDKSIREIENEANNLNNKY------------NEIQEN 641
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 605 RKQAEiECKNKEEVMAVRLREADSIA-AVAELRQHIaeLEIQKEEGKLQGQLNKSDSNQY------------IGELKDQI 671
Cdd:PRK01156 642 KILIE-KLRGKIDNYKKQIAEIDSIIpDLKEITSRI--NDIEDNLKKSRKALDDAKANRArlestieilrtrINELSDRI 718
|
....*...
gi 1370454477 672 AELNHEGE 679
Cdd:PRK01156 719 NDINETLE 726
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
320-637 |
8.82e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.89 E-value: 8.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 320 KKLE--KEYTTIKTKEMEEQVE-IKRLRTENRLLKQRIETLEkESASLADRLI-----QGQVTRAQEAEENYLIKRELAT 391
Cdd:pfam10174 401 KKIEnlQEQLRDKDKQLAGLKErVKSLQTDSSNTDTALTTLE-EALSEKERIIerlkeQREREDRERLEELESLKKENKD 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 392 IKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQAR-------------LSEAESQCALKEMQDK 458
Cdd:pfam10174 480 LKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKeecsklenqlkkaHNAEEAVRTNPEINDR 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 459 VLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKElrQQVKDLEEHWQRHLarttgrwKDPPKKNAMNELQDELM 538
Cdd:pfam10174 560 IRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD--KKIAELESLTLRQM-------KEQNKKVANIKHGQQEM 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 539 tiRLREAETQAEIREIKQRMMEMETQNQINS--NHLRRAEQEVISLQEKV---QYLSAQNKGLLTQLSEAKRKQAEIECK 613
Cdd:pfam10174 631 --KKKGAQLLEEARRREDNLADNSQQLQLEElmGALEKTRQELDATKARLsstQQSLAEKDGHLTNLRAERRKQLEEILE 708
|
330 340
....*....|....*....|....
gi 1370454477 614 NKEEVMAVRLREADSIAAVAELRQ 637
Cdd:pfam10174 709 MKQEALLAAISEKDANIALLELSS 732
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
401-581 |
1.13e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.45 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 401 AKLEQAENTIRKLQHQQQwhkcssNYNEdfvLQLEKELVQARLSEAESQcaLKEMQDKVLDIEKRNNSLPDENNIARLQE 480
Cdd:COG4717 71 KELKELEEELKEAEEKEE------EYAE---LQEELEELEEELEELEAE--LEELREELEKLEKLLQLLPLYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 481 ELIAVKLREAEAIMGLKELRQQVKDLE------EHWQRHLARTTGRWkDPPKKNAMNELQDELMTIRLREAETQAEIREI 554
Cdd:COG4717 140 ELAELPERLEELEERLEELRELEEELEeleaelAELQEELEELLEQL-SLATEEELQDLAEELEELQQRLAELEEELEEA 218
|
170 180
....*....|....*....|....*...
gi 1370454477 555 KQRMMEMETQ-NQINSNHLRRAEQEVIS 581
Cdd:COG4717 219 QEELEELEEElEQLENELEAAALEERLK 246
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
434-652 |
1.28e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 434 LEKEL--VQARLSEAESqcALKEMQDK--VLDIEKRNNSLpdENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEeh 509
Cdd:COG3206 180 LEEQLpeLRKELEEAEA--ALEEFRQKngLVDLSEEAKLL--LQQLSELESQLAEARAELAEAEARLAALRAQLGSGP-- 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 510 wqrhlarttgrwkdppkkNAMNELQD--ELMTIRLREAETQAEIREIKQRMMEmetqnqinsNHlrraeQEVISLQEKVQ 587
Cdd:COG3206 254 ------------------DALPELLQspVIQQLRAQLAELEAELAELSARYTP---------NH-----PDVIALRAQIA 301
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454477 588 YLSAQNKglltqlSEAKRKQAEIEcknkEEVMAVRLREADSIAAVAELRQHIAEL-EIQKEEGKLQ 652
Cdd:COG3206 302 ALRAQLQ------QEAQRILASLE----AELEALQAREASLQAQLAQLEARLAELpELEAELRRLE 357
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
296-675 |
1.53e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.93 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 296 HQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLL-------KQRIETLEKESASLADRL 368
Cdd:TIGR04523 33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLndklkknKDKINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 369 -IQGQVTRAQEAEENYL------IKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQA 441
Cdd:TIGR04523 113 kNDKEQKNKLEVELNKLekqkkeNKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKI 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 442 RLSEAESQCAL----------KEMQDKVLDIEKRNNSLpdENNIARLQEELIAVKL---REAEAIMGLKELRQQVKDLEE 508
Cdd:TIGR04523 193 KNKLLKLELLLsnlkkkiqknKSLESQISELKKQNNQL--KDNIEKKQQEINEKTTeisNTQTQLNQLKDEQNKIKKQLS 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 509 HWQRHLARTTGRWKDppKKNAMNELQDELMTI---------------------RLREAETQ------------AEIREIK 555
Cdd:TIGR04523 271 EKQKELEQNNKKIKE--LEKQLNQLKSEISDLnnqkeqdwnkelkselknqekKLEEIQNQisqnnkiisqlnEQISQLK 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 556 QRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKeevmavrlreadsiaavaEL 635
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ------------------QK 410
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1370454477 636 RQHIAELEIQKEEGKLQGQLNKS---DSNQYIGELKDQIAELN 675
Cdd:TIGR04523 411 DEQIKKLQQEKELLEKEIERLKEtiiKNNSEIKDLTNQDSVKE 453
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
383-550 |
1.86e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 383 YLIKRELATIKQQSDEASAK--LEQAE---NTIRK---LQHQQQWHKCSSnynedfvlQLEKELVQAR--LSEAESQCAL 452
Cdd:PRK12704 22 YFVRKKIAEAKIKEAEEEAKriLEEAKkeaEAIKKealLEAKEEIHKLRN--------EFEKELRERRneLQKLEKRLLQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 453 KEMQ--DKVLDIEKRNNSLPD-ENNIARLQEEliavklreaeaimgLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNA 529
Cdd:PRK12704 94 KEENldRKLELLEKREEELEKkEKELEQKQQE--------------LEKKEEELEELIEEQLQELERISGLTAEEAKEIL 159
|
170 180
....*....|....*....|....
gi 1370454477 530 MNELQDEL---MTIRLREAETQAE 550
Cdd:PRK12704 160 LEKVEEEArheAAVLIKEIEEEAK 183
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
297-498 |
1.95e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 297 QFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLiqGQVTRA 376
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL--GERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 377 ---QEAEENYL------------IKReLATIKQQSDEASAKLEQAENTIRKLQHQQQwhkcssnynedfvlQLEKELVQA 441
Cdd:COG3883 95 lyrSGGSVSYLdvllgsesfsdfLDR-LSALSKIADADADLLEELKADKAELEAKKA--------------ELEAKLAEL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1370454477 442 RLSEAESQCALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKE 498
Cdd:COG3883 160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
317-675 |
2.55e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.54 E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRL--IQGQV--TRAQEAEENYLI------- 385
Cdd:TIGR04523 131 KQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKlnIQKNIdkIKNKLLKLELLLsnlkkki 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 386 -------------KRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQA--RLSEAESQC 450
Cdd:TIGR04523 211 qknkslesqiselKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNnkKIKELEKQL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 451 ALKEMQDKVLDIEKRNNSLPD-ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHwqrhlaRTTGRWKDPPKKNA 529
Cdd:TIGR04523 291 NQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE------LTNSESENSEKQRE 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 530 MNELQDELMTIRLREAETQAEIREIKQRMMEMETQ-------NQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSE 602
Cdd:TIGR04523 365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKiqnqeklNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 603 AKRKQAEIECKNK---------EEVMAVRLREADSIAAvaELRQHIAELEIQKEEGKlqgQLN--KSDSNQYIGELKDQI 671
Cdd:TIGR04523 445 LTNQDSVKELIIKnldntreslETQLKVLSRSINKIKQ--NLEQKQKELKSKEKELK---KLNeeKKELEEKVKDLTKKI 519
|
....
gi 1370454477 672 AELN 675
Cdd:TIGR04523 520 SSLK 523
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
527-688 |
2.74e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 527 KNAMNELQDELMTIR--LREAEtqAEIREIKQR--MMEMETQNQINSNHLRRAEQEVISLQekvqylsaqnkgllTQLSE 602
Cdd:COG3206 174 RKALEFLEEQLPELRkeLEEAE--AALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEAR--------------AELAE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 603 AKRKQAEIECKNKEEVMAVRLREADSiaAVAELRQHIAELEIQKEEgkLQGQLnkSDSNQYIGELKDQIAELnhEGELGR 682
Cdd:COG3206 238 AEARLAALRAQLGSGPDALPELLQSP--VIQQLRAQLAELEAELAE--LSARY--TPNHPDVIALRAQIAAL--RAQLQQ 309
|
....*.
gi 1370454477 683 EGRNVI 688
Cdd:COG3206 310 EAQRIL 315
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
317-592 |
2.90e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADR-----------------LIQGQVTRAQEA 379
Cdd:COG4717 192 EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaallALLGLGGSLLSL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 380 EEN----------------YLIKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARL 443
Cdd:COG4717 272 ILTiagvlflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 444 SEAESQCALKEMQdkVLDIEKRNNSLPDENNIArlQEELIAVKLREAEAimgLKELRQQVKDLEEHWQRHLARTTGRWKD 523
Cdd:COG4717 352 LLREAEELEEELQ--LEELEQEIAALLAEAGVE--DEEELRAALEQAEE---YQELKEELEELEEQLEELLGELEELLEA 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370454477 524 PPKKNAMNELQDELMTIRLREAET---QAEIREIKQRMMEMETQNQinsnhLRRAEQEVISLQEKVQYLSAQ 592
Cdd:COG4717 425 LDEEELEEELEELEEELEELEEELeelREELAELEAELEQLEEDGE-----LAELLQELEELKAELRELAEE 491
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
317-673 |
3.84e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.77 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQS 396
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 397 DEASAKLEQAENTIRKLQhqqqwhkcssnyNEDFVLQLE-KELVQARLSEaesqcalkEMQDKVLDIEKRNNslpdENNI 475
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLT------------NQDSVKELIiKNLDNTRESL--------ETQLKVLSRSINKI----KQNL 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 476 ARLQEELiavKLREAEaimgLKELRQQVKDLEEhwqrhlarttgRWKDPPKKNAMNELQDELMTIRLREAETqaEIREIK 555
Cdd:TIGR04523 485 EQKQKEL---KSKEKE----LKKLNEEKKELEE-----------KVKDLTKKISSLKEKIEKLESEKKEKES--KISDLE 544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 556 QRMMEMETQNqiNSNHLrraEQEVISLQEKVQYLSAQNKGLltqlsEAKRKQAEIECKNKE-EVMAVRLREADSIAAVAE 634
Cdd:TIGR04523 545 DELNKDDFEL--KKENL---EKEIDEKNKEIEELKQTQKSL-----KKKQEEKQELIDQKEkEKKDLIKEIEEKEKKISS 614
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1370454477 635 LRQHIAelEIQKEEGKLQGQLNKSDS-----NQYIGELKDQIAE 673
Cdd:TIGR04523 615 LEKELE--KAKKENEKLSSIIKNIKSkknklKQEVKQIKETIKE 656
|
|
| DUF1129 |
pfam06570 |
Protein of unknown function (DUF1129); This family consists of several hypothetical bacterial ... |
424-464 |
5.11e-03 |
|
Protein of unknown function (DUF1129); This family consists of several hypothetical bacterial proteins of unknown function.
Pssm-ID: 429008 Cd Length: 200 Bit Score: 39.18 E-value: 5.11e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1370454477 424 SNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEK 464
Cdd:pfam06570 3 TKKNQDYIFRLTKQLIKDGKSDEEIKEILDEMLPEILEGQK 43
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
350-579 |
6.46e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.28 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 350 LKQRIETLEK-ESASLADRLIQGQVTRAQEaeenYL-----IKRELATIKQQSDEASAKLEQAENTIRKLQHQQQwhkcs 423
Cdd:PRK11281 41 VQAQLDALNKqKLLEAEDKLVQQDLEQTLA----LLdkidrQKEETEQLKQQLAQAPAKLRQAQAELEALKDDND----- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 424 SNYNEDF----VLQLEKEL---------VQARLSEAES------------QCALKEMQDKVLDIEKRNNSLPDENN---- 474
Cdd:PRK11281 112 EETRETLstlsLRQLESRLaqtldqlqnAQNDLAEYNSqlvslqtqperaQAALYANSQRLQQIRNLLKGGKVGGKalrp 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 475 --IARLQEELIAVKL------REAEAIMGLKELRQQVKDLEEHWQRHLARTTgrwkdppkknamNELQDELMTIRLREAE 546
Cdd:PRK11281 192 sqRVLLQAEQALLNAqndlqrKSLEGNTQLQDLLQKQRDYLTARIQRLEHQL------------QLLQEAINSKRLTLSE 259
|
250 260 270
....*....|....*....|....*....|....*.
gi 1370454477 547 TQAEireikqrmmEMETQ---NQINSNHLRRAEQEV 579
Cdd:PRK11281 260 KTVQ---------EAQSQdeaARIQANPLVAQELEI 286
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
472-679 |
6.76e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 39.81 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 472 ENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGrwkdppKKNAMNELQDELmtirlreAETQAEI 551
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEA------LQAEIDKLQAEI-------AEAEAEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 552 REIKQRMMEMETQNQINSNHLRRAE--------QEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEvmavrl 623
Cdd:COG3883 82 EERREELGERARALYRSGGSVSYLDvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK------ 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454477 624 rEADSIAAVAELRQHIAELEIQKEEgkLQGQLNKSDSNQyiGELKDQIAELNHEGE 679
Cdd:COG3883 156 -LAELEALKAELEAAKAELEAQQAE--QEALLAQLSAEE--AAAEAQLAELEAELA 206
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
428-686 |
7.46e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.16 E-value: 7.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 428 EDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPD----ENNIARLQEEL---IAVKLREAEAIMG----- 495
Cdd:pfam01576 4 EEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEqlqaETELCAEAEEMrarLAARKQELEEILHelesr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 496 --------------LKELRQQVKDLEEHW-QRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMME 560
Cdd:pfam01576 84 leeeeersqqlqneKKKMQQHIQDLEEQLdEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 561 METQnqinsnhLRRAEQEVISLQEkvqyLSAQNKGLLTQLS-----EAKRKQAEIECKNKEEVMAVRLREadsiaAVAEL 635
Cdd:pfam01576 164 FTSN-------LAEEEEKAKSLSK----LKNKHEAMISDLEerlkkEEKGRQELEKAKRKLEGESTDLQE-----QIAEL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370454477 636 RQHIAELEIQ--KEEGKLQGQLNKSDSNQ--------YIGELKDQIAELNHEGELGREGRN 686
Cdd:pfam01576 228 QAQIAELRAQlaKKEEELQAALARLEEETaqknnalkKIRELEAQISELQEDLESERAARN 288
|
|
| Fibrinogen_BP |
pfam08017 |
Fibrinogen binding protein; Proteins in this family bind to fibrinogen. Members of this family ... |
435-666 |
8.02e-03 |
|
Fibrinogen binding protein; Proteins in this family bind to fibrinogen. Members of this family includes the fibrinogen receptor, FbsA, which mediates platelet aggregation.
Pssm-ID: 311808 [Multi-domain] Cd Length: 393 Bit Score: 39.46 E-value: 8.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 435 EKELVQARLSEAESQCALKEMQDKVLDIEKRN--NSLPDENNIARLQEELIAVKLREAEAimglkELRQQVKDLEEHWQR 512
Cdd:pfam08017 75 QGNVLERRQRDAENRSQGNVLERRQRDAENRSqgNVLERRQRDAENKSQGNVLERRQRDA-----ENRSQGNVLERRQRD 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 513 HLARTTGRWKDPPKKNAMNELQDELMTIRLREAE--TQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLS 590
Cdd:pfam08017 150 AENRSQGNVLERRQRDAENRSQGNVLERRQRDAEnkSQGNVLERRQRDAENRSQGNVLERRQRDAENRSQGNVLERRQRD 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 591 AQNKgllTQLSEAKRKQAEIECKNKEEVMAVRLREAD--SIAAVAELRQHIAELEIQKE--EGKLQGQLNKSDSNQYIGE 666
Cdd:pfam08017 230 AENR---SQGNVLERRQRDAENKSQGNVLERRQRDAEnrSQGNVLERRQRDAENRSQGNvlERRQRDAENKSQVGQLIGK 306
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
433-680 |
8.11e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 39.82 E-value: 8.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 433 QLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLpdENNIARLQ---------EELIAVKLREAEAimGLKELRQQV 503
Cdd:pfam12128 217 RLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTL--ESAELRLShlhfgyksdETLIASRQEERQE--TSAELNQLL 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 504 KDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLReaetQAEIREIKQRMMEMETQNQINSNhlrraeqevISLQ 583
Cdd:pfam12128 293 RTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHG----AFLDADIETAAADQEQLPSWQSE---------LENL 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 584 EKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRL----READSIAAVAE--LRQHIAELEIQKEEGKLQGQLNK 657
Cdd:pfam12128 360 EERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLakirEARDRQLAVAEddLQALESELREQLEAGKLEFNEEE 439
|
250 260
....*....|....*....|...
gi 1370454477 658 SDSNQYIGELKDQIAELNHEGEL 680
Cdd:pfam12128 440 YRLKSRLGELKLRLNQATATPEL 462
|
|
| BicD |
pfam09730 |
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled ... |
528-721 |
8.98e-03 |
|
Microtubule-associated protein Bicaudal-D; BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.
Pssm-ID: 462863 [Multi-domain] Cd Length: 717 Bit Score: 39.46 E-value: 8.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 528 NAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQ---INSNHLR------------------RAEQEVISLQEKV 586
Cdd:pfam09730 34 QRILELQNELKQARAVLSNTQAENERLASLSQELKEECEcveLQRGRMRdeikeykvrearllqdysELEEENISLQKQV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 587 QYLSaQNKGLLTQLS-EAKRKQAEIECKNKEEVMAVRLREadsiaaVAElRQHIAELEIQKEEGKLQGQLNKSDSNQ--- 662
Cdd:pfam09730 114 SVLK-QNQVEFEGLKhEITRKEEETELLNSQLEEAIRLRE------IAE-RQLDEALETLKTEREQKNSLRKELSHYmtl 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370454477 663 ----YIGELKDQIAELNHEGELGREGRnvipdwhsPHAEGNLMSGKQHSSPTLRCLKGQRGFS 721
Cdd:pfam09730 186 ndfdYVSHLSISLDGLKFSEDEGAGTE--------PNNDGEAMDGGENGGGGLKNSGLDNRTS 240
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
317-618 |
9.24e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 39.62 E-value: 9.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 317 KKMKKLEKEY-TTIKTKEMEEQV---EIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATI 392
Cdd:TIGR04523 401 QNQEKLNQQKdEQIKKLQQEKELlekEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 393 KQQSDEASAKLEQAENTIRKLQHQQqwhKCSSNYNEDFVLQLEKELVQARLSEAEsqcaLKEMQDKVLDIEKRNNSLPDE 472
Cdd:TIGR04523 481 KQNLEQKQKELKSKEKELKKLNEEK---KELEEKVKDLTKKISSLKEKIEKLESE----KKEKESKISDLEDELNKDDFE 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370454477 473 NNIARLQEELIAVKLReaeaimgLKELRQQVKDLEEhwqrhlarttgrwKDPPKKNAMNELQDELMTIRLREAETQAEIR 552
Cdd:TIGR04523 554 LKKENLEKEIDEKNKE-------IEELKQTQKSLKK-------------KQEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370454477 553 EIKQRMMEMETQNqinsnhlRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEV 618
Cdd:TIGR04523 614 SLEKELEKAKKEN-------EKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESK 672
|
|
| |
