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Conserved domains on  [gi|1370477886|ref|XP_024308716|]
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cysteine-rich motor neuron 1 protein isoform X11 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CRIM1_C super family cl44859
Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) ...
 749-878 6.81e-77

Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) interacts with growth factors implicated in motor neuron differentiation and survival, playing a role in central nervous system development. It is upregulated in endothelial cells during tube formation. CRIM1 also modulates BMP activity, which affects its processing and delivery to the cell surface. This is CRIM1 C-terminal domain containing the transmembrane region.


The actual alignment was detected with superfamily member pfam19442:

Pssm-ID: 437274  Cd Length: 130  Bit Score: 245.92  E-value: 6.81e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370477886 749 ENDIVHLPRDMGHLQVDYRD-NRLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCwYRTPTKPSSLNNQ 827
Cdd:pfam19442   1 ENDIVHQPRDMGHLQVDYREgSRPHPSEDSSLHSVAWVTVPIMIALVLIIALLLINQKKQWIPVPC-YRTPTKPSCLNNQ 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370477886 828 LVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV 878
Cdd:pfam19442  80 LVYVDCKKGTMVQVDSSQRMLRIADPDSRYSGFYSMQKQNNLQADNFYQTV 130
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 525-576 3.31e-06

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 45.11  E-value: 3.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 525 GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQ--DSCCPQC 576
Cdd:pfam00093   4 NGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 661-715 1.26e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 43.57  E-value: 1.26e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 661 CHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEP--INVEGSCCPMC 715
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
245-298 4.55e-05

von Willebrand factor (vWF) type C domain;


:

Pssm-ID: 214564  Cd Length: 59  Bit Score: 41.73  E-value: 4.55e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  245 CYANGLILAHGDRWREDDCTFCQCVNGER-HCVATVC--GQTCTNP--VKVPGECCPVC 298
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECppPPDCPNPerVKPPGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
178-232 1.31e-04

von Willebrand factor (vWF) type C domain;


:

Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.58  E-value: 1.31e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  178 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAI-CFTAQCGE-INCERYY--VPEGECCPVC 232
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTVlCDPVECPPpPDCPNPErvKPPGECCPRC 59
Antistasin pfam02822
Antistasin family; Members of this family are inhibitors of trypsin family proteases. This ...
 409-434 2.71e-04

Antistasin family; Members of this family are inhibitors of trypsin family proteases. This domain is highly disulphide bonded. The domain is also found in some large extracellular proteins in multiple copies.


:

Pssm-ID: 460713  Cd Length: 26  Bit Score: 38.69  E-value: 2.71e-04
                          10        20
                  ....*....|....*....|....*.
gi 1370477886 409 CPELSCSKICPLGFQQDSHGCLICKC 434
Cdd:pfam02822   1 CPPLNCRLKCPYGFQTDENGCPTCEC 26
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 600-650 4.77e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member smart00214:

Pssm-ID: 450195  Cd Length: 59  Bit Score: 39.04  E-value: 4.77e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370477886  600 GDIFLAAESWKPDVCTSCICIDS-VISCFSESCPSV-SCERPVLRK--GQCCPYC 650
Cdd:smart00214   5 GRVYNDGETWKPDPCQICTCLDGtTVLCDPVECPPPpDCPNPERVKppGECCPRC 59
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 454-504 1.94e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 37.40  E-value: 1.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 454 DGHHHKNEESWH-DGCRECYCLNGREMCALITCPVPACGNPT--IHPGQCCPSC 504
Cdd:pfam00093   4 NGVVYENGETWKpDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
 
Name Accession Description Interval E-value
CRIM1_C pfam19442
Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) ...
 749-878 6.81e-77

Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) interacts with growth factors implicated in motor neuron differentiation and survival, playing a role in central nervous system development. It is upregulated in endothelial cells during tube formation. CRIM1 also modulates BMP activity, which affects its processing and delivery to the cell surface. This is CRIM1 C-terminal domain containing the transmembrane region.


Pssm-ID: 437274  Cd Length: 130  Bit Score: 245.92  E-value: 6.81e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370477886 749 ENDIVHLPRDMGHLQVDYRD-NRLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCwYRTPTKPSSLNNQ 827
Cdd:pfam19442   1 ENDIVHQPRDMGHLQVDYREgSRPHPSEDSSLHSVAWVTVPIMIALVLIIALLLINQKKQWIPVPC-YRTPTKPSCLNNQ 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370477886 828 LVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV 878
Cdd:pfam19442  80 LVYVDCKKGTMVQVDSSQRMLRIADPDSRYSGFYSMQKQNNLQADNFYQTV 130
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 525-576 3.31e-06

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 45.11  E-value: 3.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 525 GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQ--DSCCPQC 576
Cdd:pfam00093   4 NGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 661-715 1.26e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 43.57  E-value: 1.26e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 661 CHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEP--INVEGSCCPMC 715
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
245-298 4.55e-05

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 41.73  E-value: 4.55e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  245 CYANGLILAHGDRWREDDCTFCQCVNGER-HCVATVC--GQTCTNP--VKVPGECCPVC 298
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECppPPDCPNPerVKPPGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
525-576 1.07e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.96  E-value: 1.07e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370477886  525 GGEYFVEGETWNIDSCTQCTCHSGR-VLCETEVCPP-LLCQNPSRTQ--DSCCPQC 576
Cdd:smart00214   4 NGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNPERVKppGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
178-232 1.31e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.58  E-value: 1.31e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  178 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAI-CFTAQCGE-INCERYY--VPEGECCPVC 232
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTVlCDPVECPPpPDCPNPErvKPPGECCPRC 59
Antistasin pfam02822
Antistasin family; Members of this family are inhibitors of trypsin family proteases. This ...
 409-434 2.71e-04

Antistasin family; Members of this family are inhibitors of trypsin family proteases. This domain is highly disulphide bonded. The domain is also found in some large extracellular proteins in multiple copies.


Pssm-ID: 460713  Cd Length: 26  Bit Score: 38.69  E-value: 2.71e-04
                          10        20
                  ....*....|....*....|....*.
gi 1370477886 409 CPELSCSKICPLGFQQDSHGCLICKC 434
Cdd:pfam02822   1 CPPLNCRLKCPYGFQTDENGCPTCEC 26
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 178-232 2.81e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 39.72  E-value: 2.81e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 178 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCE--RYYVPEGECCPVC 232
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPnpRLEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
661-715 3.51e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.42  E-value: 3.51e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  661 CHFSGKAYADEERWDLDSCTHCYCLQGQT-LCSTVSCPPLPCV---EPINVEGSCCPMC 715
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECPPPPDCpnpERVKPPGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
600-650 4.77e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.04  E-value: 4.77e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370477886  600 GDIFLAAESWKPDVCTSCICIDS-VISCFSESCPSV-SCERPVLRK--GQCCPYC 650
Cdd:smart00214   5 GRVYNDGETWKPDPCQICTCLDGtTVLCDPVECPPPpDCPNPERVKppGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 600-650 5.02e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 38.94  E-value: 5.02e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370477886 600 GDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRK--GQCCPYC 650
Cdd:pfam00093   5 GVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 454-504 1.94e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 37.40  E-value: 1.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 454 DGHHHKNEESWH-DGCRECYCLNGREMCALITCPVPACGNPT--IHPGQCCPSC 504
Cdd:pfam00093   4 NGVVYENGETWKpDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 245-298 4.38e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 36.25  E-value: 4.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 245 CYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQ-TCTNP--VKVPGECCPVC 298
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPlDCPNPrlEIPPGECCPVC 57
 
Name Accession Description Interval E-value
CRIM1_C pfam19442
Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) ...
 749-878 6.81e-77

Cysteine-rich motor neuron 1 protein C-terminal; Cysteine-rich motor neuron 1 protein (CRIM1) interacts with growth factors implicated in motor neuron differentiation and survival, playing a role in central nervous system development. It is upregulated in endothelial cells during tube formation. CRIM1 also modulates BMP activity, which affects its processing and delivery to the cell surface. This is CRIM1 C-terminal domain containing the transmembrane region.


Pssm-ID: 437274  Cd Length: 130  Bit Score: 245.92  E-value: 6.81e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370477886 749 ENDIVHLPRDMGHLQVDYRD-NRLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCwYRTPTKPSSLNNQ 827
Cdd:pfam19442   1 ENDIVHQPRDMGHLQVDYREgSRPHPSEDSSLHSVAWVTVPIMIALVLIIALLLINQKKQWIPVPC-YRTPTKPSCLNNQ 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370477886 828 LVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV 878
Cdd:pfam19442  80 LVYVDCKKGTMVQVDSSQRMLRIADPDSRYSGFYSMQKQNNLQADNFYQTV 130
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 525-576 3.31e-06

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 45.11  E-value: 3.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 525 GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQ--DSCCPQC 576
Cdd:pfam00093   4 NGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 661-715 1.26e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 43.57  E-value: 1.26e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 661 CHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEP--INVEGSCCPMC 715
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
245-298 4.55e-05

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 41.73  E-value: 4.55e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  245 CYANGLILAHGDRWREDDCTFCQCVNGER-HCVATVC--GQTCTNP--VKVPGECCPVC 298
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECppPPDCPNPerVKPPGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
525-576 1.07e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.96  E-value: 1.07e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370477886  525 GGEYFVEGETWNIDSCTQCTCHSGR-VLCETEVCPP-LLCQNPSRTQ--DSCCPQC 576
Cdd:smart00214   4 NGRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPpPDCPNPERVKppGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
178-232 1.31e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.58  E-value: 1.31e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  178 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAI-CFTAQCGE-INCERYY--VPEGECCPVC 232
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTVlCDPVECPPpPDCPNPErvKPPGECCPRC 59
Antistasin pfam02822
Antistasin family; Members of this family are inhibitors of trypsin family proteases. This ...
 409-434 2.71e-04

Antistasin family; Members of this family are inhibitors of trypsin family proteases. This domain is highly disulphide bonded. The domain is also found in some large extracellular proteins in multiple copies.


Pssm-ID: 460713  Cd Length: 26  Bit Score: 38.69  E-value: 2.71e-04
                          10        20
                  ....*....|....*....|....*.
gi 1370477886 409 CPELSCSKICPLGFQQDSHGCLICKC 434
Cdd:pfam02822   1 CPPLNCRLKCPYGFQTDENGCPTCEC 26
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 178-232 2.81e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 39.72  E-value: 2.81e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 178 CVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCE--RYYVPEGECCPVC 232
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPnpRLEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
661-715 3.51e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.42  E-value: 3.51e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370477886  661 CHFSGKAYADEERWDLDSCTHCYCLQGQT-LCSTVSCPPLPCV---EPINVEGSCCPMC 715
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECPPPPDCpnpERVKPPGECCPRC 59
VWC smart00214
von Willebrand factor (vWF) type C domain;
600-650 4.77e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.04  E-value: 4.77e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370477886  600 GDIFLAAESWKPDVCTSCICIDS-VISCFSESCPSV-SCERPVLRK--GQCCPYC 650
Cdd:smart00214   5 GRVYNDGETWKPDPCQICTCLDGtTVLCDPVECPPPpDCPNPERVKppGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 600-650 5.02e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 38.94  E-value: 5.02e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1370477886 600 GDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRK--GQCCPYC 650
Cdd:pfam00093   5 GVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 454-504 1.94e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 37.40  E-value: 1.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1370477886 454 DGHHHKNEESWH-DGCRECYCLNGREMCALITCPVPACGNPT--IHPGQCCPSC 504
Cdd:pfam00093   4 NGVVYENGETWKpDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 669-715 2.59e-03

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 41.22  E-value: 2.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370477886 669 ADEERWDLDSCTH---CYC---LQGQTLCSTVS--CPPLPCVEPINVEGSCCPMC 715
Cdd:pfam14828 181 AGALRVGPEACSDpsgCGCgndENLERICANVLqrCPPPHCLSPLRPEGHCCDVC 235
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 245-298 4.38e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 36.25  E-value: 4.38e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370477886 245 CYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQ-TCTNP--VKVPGECCPVC 298
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPlDCPNPrlEIPPGECCPVC 57
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 262-298 5.87e-03

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 40.06  E-value: 5.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1370477886 262 DCTFCQC---VNGERHC--VATVCGQ-TCTNPVKVPGECCPVC 298
Cdd:pfam14828 193 DPSGCGCgndENLERICanVLQRCPPpHCLSPLRPEGHCCDVC 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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