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Conserved domains on  [gi|1443091789|ref|XP_025882908|]
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cysteine-tryptophan domain-containing zinc finger protein 7 isoform X2 [Oryza sativa Japonica Group]

Protein Classification

cysteine-tryptophan domain-containing zinc finger protein( domain architecture ID 10539294)

cysteine-tryptophan (CW) domain-containing zinc finger protein may be involved in histone recognition

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CW pfam07496
CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four ...
 648-694 1.04e-16

CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four conserved cysteine residues and a conserved tryptophan. It was first identified by, and is predicted to be a "highly specialized mononuclear four-cysteine zinc finger...that plays a role in DNA binding and/or promoting protein-protein interactions in complicated eukaryotic processes including...chromatin methylation status and early embryonic development." Weak homology to pfam00628 further evidences these predictions (personal obs: C Yeats). Twelve different CW-domain-containing protein subfamilies are described, with different subfamilies being characteriztic of vertebrates, higher plants and other animals in which these domain is found.


:

Pssm-ID: 462181  Cd Length: 46  Bit Score: 75.04  E-value: 1.04e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1443091789  648 HWVCCDICQKWRLLPYKMNPSLLPKKWKCSMLQWlPGMNRCEVSEDE 694
Cdd:pfam07496    1 YWVQCDSCLKWRRLPTEIDPYELPEPWYCSMNPD-PKYNSCDAPEEI 46
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 526-642 1.24e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443091789  526 SSGAVKERKNDSQSKSSHPGRKPKAKSHRDV-------REHLPEgsyggKDDTLENgsglgelRPKKIWKNDSERDSDMP 598
Cdd:PTZ00449   527 KEGEEGEHEDSKESDEPKEGGKPGETKEGEVgkkpgpaKEHKPS-----KIPTLSK-------KPEFPKDPKHPKDPEEP 594

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1443091789  599 GTSKREISSSLKNDRHTPAEEQRMHVPPSVSAPTANAAPMLPAP 642
Cdd:PTZ00449   595 KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPP 638
 
Name Accession Description Interval E-value
zf-CW pfam07496
CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four ...
 648-694 1.04e-16

CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four conserved cysteine residues and a conserved tryptophan. It was first identified by, and is predicted to be a "highly specialized mononuclear four-cysteine zinc finger...that plays a role in DNA binding and/or promoting protein-protein interactions in complicated eukaryotic processes including...chromatin methylation status and early embryonic development." Weak homology to pfam00628 further evidences these predictions (personal obs: C Yeats). Twelve different CW-domain-containing protein subfamilies are described, with different subfamilies being characteriztic of vertebrates, higher plants and other animals in which these domain is found.


Pssm-ID: 462181  Cd Length: 46  Bit Score: 75.04  E-value: 1.04e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1443091789  648 HWVCCDICQKWRLLPYKMNPSLLPKKWKCSMLQWlPGMNRCEVSEDE 694
Cdd:pfam07496    1 YWVQCDSCLKWRRLPTEIDPYELPEPWYCSMNPD-PKYNSCDAPEEI 46
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 526-642 1.24e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443091789  526 SSGAVKERKNDSQSKSSHPGRKPKAKSHRDV-------REHLPEgsyggKDDTLENgsglgelRPKKIWKNDSERDSDMP 598
Cdd:PTZ00449   527 KEGEEGEHEDSKESDEPKEGGKPGETKEGEVgkkpgpaKEHKPS-----KIPTLSK-------KPEFPKDPKHPKDPEEP 594

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1443091789  599 GTSKREISSSLKNDRHTPAEEQRMHVPPSVSAPTANAAPMLPAP 642
Cdd:PTZ00449   595 KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPP 638
 
Name Accession Description Interval E-value
zf-CW pfam07496
CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four ...
 648-694 1.04e-16

CW-type Zinc Finger; This domain appears to be a zinc finger. The alignment shows four conserved cysteine residues and a conserved tryptophan. It was first identified by, and is predicted to be a "highly specialized mononuclear four-cysteine zinc finger...that plays a role in DNA binding and/or promoting protein-protein interactions in complicated eukaryotic processes including...chromatin methylation status and early embryonic development." Weak homology to pfam00628 further evidences these predictions (personal obs: C Yeats). Twelve different CW-domain-containing protein subfamilies are described, with different subfamilies being characteriztic of vertebrates, higher plants and other animals in which these domain is found.


Pssm-ID: 462181  Cd Length: 46  Bit Score: 75.04  E-value: 1.04e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1443091789  648 HWVCCDICQKWRLLPYKMNPSLLPKKWKCSMLQWlPGMNRCEVSEDE 694
Cdd:pfam07496    1 YWVQCDSCLKWRRLPTEIDPYELPEPWYCSMNPD-PKYNSCDAPEEI 46
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 526-642 1.24e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443091789  526 SSGAVKERKNDSQSKSSHPGRKPKAKSHRDV-------REHLPEgsyggKDDTLENgsglgelRPKKIWKNDSERDSDMP 598
Cdd:PTZ00449   527 KEGEEGEHEDSKESDEPKEGGKPGETKEGEVgkkpgpaKEHKPS-----KIPTLSK-------KPEFPKDPKHPKDPEEP 594

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1443091789  599 GTSKREISSSLKNDRHTPAEEQRMHVPPSVSAPTANAAPMLPAP 642
Cdd:PTZ00449   595 KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPP 638
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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