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Conserved domains on  [gi|1720431608|ref|XP_030100221|]
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zinc finger protein 317 isoform X5 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
10-357 5.97e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.40  E-value: 5.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  10 HKCHQCQKAFTTSASLTRHHRIHTGEKPYECS--SCGKAFNDPSALRSHTRTHLKE------------------------ 63
Cdd:COG5048    34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNpsdlnskslplsnskasssslsss 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  64 -----KPFDCSQCSNAFRTLSALKIHMRVHTGERPYKCDECGKAYGRS----------------------CHLIAHKRTH 116
Cdd:COG5048   114 ssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSNVS 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 117 TGERPYECQDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLH-KKNHMVEKTYECKECGKSFSDLLSRRK 195
Cdd:COG5048   194 TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPsSLSSSDSSSSASESPRSSLPTASSQSS 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 196 H-----MRIHIVK-KPVECHQCGKTFRNQSILKTHMNS--HTGE--RPYGCD--LCGKAFSASSNLTAHRKIHTQERHYE 263
Cdd:COG5048   274 SpnesdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAK 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 264 CTSC-------GKVFGDYLSRRRHMSIHLVKKRVDC--RQCGKAFRNQSTLKTHMRSHTGEKPYECD--HCGKAFSIGSN 332
Cdd:COG5048   354 EKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYN 433

                         410       420
                  ....*....|....*....|....*
gi 1720431608 333 LNVHRRIHTGEKPYECLICGKAFSD 357
Cdd:COG5048   434 LIPHKKIHTNHAPLLCSILKSFRRD 458
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
10-357 5.97e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.40  E-value: 5.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  10 HKCHQCQKAFTTSASLTRHHRIHTGEKPYECS--SCGKAFNDPSALRSHTRTHLKE------------------------ 63
Cdd:COG5048    34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNpsdlnskslplsnskasssslsss 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  64 -----KPFDCSQCSNAFRTLSALKIHMRVHTGERPYKCDECGKAYGRS----------------------CHLIAHKRTH 116
Cdd:COG5048   114 ssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSNVS 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 117 TGERPYECQDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLH-KKNHMVEKTYECKECGKSFSDLLSRRK 195
Cdd:COG5048   194 TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPsSLSSSDSSSSASESPRSSLPTASSQSS 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 196 H-----MRIHIVK-KPVECHQCGKTFRNQSILKTHMNS--HTGE--RPYGCD--LCGKAFSASSNLTAHRKIHTQERHYE 263
Cdd:COG5048   274 SpnesdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAK 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 264 CTSC-------GKVFGDYLSRRRHMSIHLVKKRVDC--RQCGKAFRNQSTLKTHMRSHTGEKPYECD--HCGKAFSIGSN 332
Cdd:COG5048   354 EKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYN 433

                         410       420
                  ....*....|....*....|....*
gi 1720431608 333 LNVHRRIHTGEKPYECLICGKAFSD 357
Cdd:COG5048   434 LIPHKKIHTNHAPLLCSILKSFRRD 458
zf-H2C2_2 pfam13465
Zinc-finger double domain;
305-328 4.39e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 4.39e-04
                          10        20
                  ....*....|....*....|....
gi 1720431608 305 LKTHMRSHTGEKPYECDHCGKAFS 328
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 36-88 2.71e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.38  E-value: 2.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720431608  36 KPYeCSSCGKAFNDPSALRSHtrthLKEKPFDCSQCSNAFRTLSALKIH-MRVH 88
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQH----QKAKHFKCHICHKKLYTAGGLAVHcLQVH 49
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
10-357 5.97e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.40  E-value: 5.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  10 HKCHQCQKAFTTSASLTRHHRIHTGEKPYECS--SCGKAFNDPSALRSHTRTHLKE------------------------ 63
Cdd:COG5048    34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNpsdlnskslplsnskasssslsss 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  64 -----KPFDCSQCSNAFRTLSALKIHMRVHTGERPYKCDECGKAYGRS----------------------CHLIAHKRTH 116
Cdd:COG5048   114 ssnsnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSNVS 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 117 TGERPYECQDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLH-KKNHMVEKTYECKECGKSFSDLLSRRK 195
Cdd:COG5048   194 TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPsSLSSSDSSSSASESPRSSLPTASSQSS 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 196 H-----MRIHIVK-KPVECHQCGKTFRNQSILKTHMNS--HTGE--RPYGCD--LCGKAFSASSNLTAHRKIHTQERHYE 263
Cdd:COG5048   274 SpnesdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAK 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 264 CTSC-------GKVFGDYLSRRRHMSIHLVKKRVDC--RQCGKAFRNQSTLKTHMRSHTGEKPYECD--HCGKAFSIGSN 332
Cdd:COG5048   354 EKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYN 433

                         410       420
                  ....*....|....*....|....*
gi 1720431608 333 LNVHRRIHTGEKPYECLICGKAFSD 357
Cdd:COG5048   434 LIPHKKIHTNHAPLLCSILKSFRRD 458
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
24-280 1.32e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.00  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  24 SLTRHHRIHTGEKPYECSSCGKAFNDPSALRSHTRTHLKEKPFDCSQCSNAFRTLSALKIHMRVHTGERPYKCDECGKAY 103
Cdd:COG5048   185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 104 G--RSCHLIAHKRTHTGER-----PYECQDCGKAFQHPSHLKEHVR--NHTGE--KPYECT--QCGKAFRWKSNFNLHKK 170
Cdd:COG5048   265 LptASSQSSSPNESDSSSEkgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPysLCGKLFSRNDALKRHIL 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 171 NHMVEKTYECK--ECGKSFSDLLSRRKHMRIHIVK-----KPVEC--HQCGKTFRNQSILKTHMNSHTGERPYGCD--LC 239
Cdd:COG5048   345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKdlkndKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPC 424

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1720431608 240 GKAFSASSNLTAHRKIHTQERHYECTSCGKVFGDYLSRRRH 280
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHG 465
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
36-351 3.73e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 3.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  36 KPYECSSCGKAFNDPSALRSHTRTHLKEKPFDCSQ--CSNAFRTLSALKIHMRVHTGERPYKC-DECGKAYGRSCHLIAH 112
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 113 KRTHTGERPYECQDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLHKKNHMVEKTyeckecGKSFSDLLS 192
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL------SKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 193 RRKHMRIHIVKKPVECHQCGKTFRNQSILKTHMNSHTGERPYGCDLCGKAFSASSNLTAHRKIHTQERHYECTSCGKVFG 272
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 273 DYLSRRRHMSIHL-------VKKRVDCRQCGKAFRNQSTLKTHMRS--HTGE--KPYECDH--CGKAFSIGSNLNVHRRI 339
Cdd:COG5048   266 PTASSQSSSPNESdsssekgFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330
                  ....*....|..
gi 1720431608 340 HTGEKPYECLIC 351
Cdd:COG5048   346 HTSISPAKEKLL 357
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
92-373 4.52e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 4.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  92 RPYKCDECGKAYGRSCHLIAHKRTHTGERPYECQD--CGKAFQHPSHLKEHVRNHTGEKPYECT-QCGKAFRWKSNFNLH 168
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 169 KKNHMVEKTYECKECGKSFSDLLSRRKHMRIHIVKKPVECHQC-GKTFRNQSILKTHMNSHTGErpygcdLCGKAFSASS 247
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnSSSVNTPQSNSLHPPLPANS------LSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 248 NLTAHRKIHTQERHYECTSCGKVFGDYLSRRRHMSIHLVkKRVDCRQCGKAF-------RNQSTLKTHMRSHTGE----- 315
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSS-SSLPLTTNSQLSpksllsqSPSSLSSSDSSSSASEsprss 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608 316 -----------------------KPYECDHCGKAFSIGSNLNVHRR--IHTGE--KPYEC--LICGKAFSDHSSLRSHVK 366
Cdd:COG5048   265 lptassqssspnesdsssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHIL 344


                  ....*..
gi 1720431608 367 THRGRSS 373
Cdd:COG5048   345 LHTSISP 351
zf-H2C2_2 pfam13465
Zinc-finger double domain;
305-328 4.39e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 4.39e-04
                          10        20
                  ....*....|....*....|....
gi 1720431608 305 LKTHMRSHTGEKPYECDHCGKAFS 328
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
8-160 9.05e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 9.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608   8 KWHKCHQCQKAFTTSASLTRH--HRIHTGE--KPYECSS--CGKAFNDPSALRSHTRTHL-----KEKPFDCS------- 69
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHlrSVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTsispaKEKLLNSSskfspll 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431608  70 -----QCSNAFRTLSALKIHMRVHTGERPYkcdeCGKAYGRSCHLIahkrTHTGERPYECQD--CGKAFQHPSHLKEHVR 142
Cdd:COG5048   368 nneppQSLQQYKDLKNDKKSETLSNSCIRN----FKRDSNLSLHII----THLSFRPYNCKNppCSKSFNRHYNLIPHKK 439

                         170
                  ....*....|....*...
gi 1720431608 143 NHTGEKPYECTQCGKAFR 160
Cdd:COG5048   440 IHTNHAPLLCSILKSFRR 457
zf-H2C2_2 pfam13465
Zinc-finger double domain;
136-159 9.07e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 9.07e-04
                          10        20
                  ....*....|....*....|....
gi 1720431608 136 HLKEHVRNHTGEKPYECTQCGKAF 159
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 36-88 2.71e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.38  E-value: 2.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720431608  36 KPYeCSSCGKAFNDPSALRSHtrthLKEKPFDCSQCSNAFRTLSALKIH-MRVH 88
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQH----QKAKHFKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
24-48 3.48e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.48e-03
                          10        20
                  ....*....|....*....|....*
gi 1720431608  24 SLTRHHRIHTGEKPYECSSCGKAFN 48
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
80-103 3.59e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 3.59e-03
                          10        20
                  ....*....|....*....|....
gi 1720431608  80 ALKIHMRVHTGERPYKCDECGKAY 103
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 295-366 4.53e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 38.93  E-value: 4.53e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720431608 295 CGKAFRNQSTLKTHMRShtgekpyecDHCGKAFSIGSNLNVHRRIHTGEKPYECLICGKAFSDHSSLRSHVK 366
Cdd:COG5189   357 CNKKYKNQNGLKYHMLH---------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
332-356 7.27e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.27e-03
                          10        20
                  ....*....|....*....|....*
gi 1720431608 332 NLNVHRRIHTGEKPYECLICGKAFS 356
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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