|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
207-304 |
3.31e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 60.72 E-value: 3.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPV----LPSgIEFLDVRLNRLQSsgiQPEAFVALKKLQFLY 282
Cdd:COG4886 137 NLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEelgnLTN-LKELDLSNNQITD---LPEPLGNLTNLEELD 211
|
90 100
....*....|....*....|....
gi 1720355545 283 LANNMLDSIPGPLPL--SLRSLHL 304
Cdd:COG4886 212 LSGNQLTDLPEPLANltNLETLDL 235
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
207-288 |
6.97e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 6.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLaalpvlpsgiefldvrlnrlqsSGIQPEAFVALKKLQFLYLANN 286
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL----------------------TTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 1720355545 287 ML 288
Cdd:pfam13855 60 RL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
158-310 |
1.28e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 50.08 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 158 QIPEAKISNLT-LPTRTSptSTVAQKTLSPNLTMAVPTTTGllnsqsshAKLRRIDLSGNSISS-------------IHN 223
Cdd:PRK15370 244 QEMELSINRITeLPERLP--SALQSLDLFHNKISCLPENLP--------EELRYLSVYDNSIRTlpahlpsgithlnVQS 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 224 DALRLLPA-----LQDLILPENQLAALPV-LPSGIEFLDVRLNRLQssgIQPEAFVAlkKLQFLYLANNMLDSIPGPLPL 297
Cdd:PRK15370 314 NSLTALPEtlppgLKTLEAGENALTSLPAsLPPELQVLDVSKNQIT---VLPETLPP--TITTLDVSRNALTNLPENLPA 388
|
170
....*....|...
gi 1720355545 298 SLRSLHLQYPLLA 310
Cdd:PRK15370 389 ALQIMQASRNNLV 401
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
207-305 |
9.68e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 39.77 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHNdaLRLLPALQDLILpENQlaalpVLPSG--IEF--------------LDVRLNRLQSsgiqPE 270
Cdd:cd21340 69 NLKKLYLGGNRISVVEG--LENLTNLEELHI-ENQ-----RLPPGekLTFdprslaalsnslrvLNISGNNIDS----LE 136
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1720355545 271 AFVALKKLQFLYLANNMLDSIPGPLPL-----SLRSLHLQ 305
Cdd:cd21340 137 PLAPLRNLEQLDASNNQISDLEELLDLlsswpSLRELDLT 176
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
207-304 |
3.31e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 60.72 E-value: 3.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPV----LPSgIEFLDVRLNRLQSsgiQPEAFVALKKLQFLY 282
Cdd:COG4886 137 NLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEelgnLTN-LKELDLSNNQITD---LPEPLGNLTNLEELD 211
|
90 100
....*....|....*....|....
gi 1720355545 283 LANNMLDSIPGPLPL--SLRSLHL 304
Cdd:COG4886 212 LSGNQLTDLPEPLANltNLETLDL 235
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
207-306 |
2.61e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 58.02 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPV----LPSgIEFLDVRLNRLQSsgiQPEAFVALKKLQFLY 282
Cdd:COG4886 160 NLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPEplgnLTN-LEELDLSGNQLTD---LPEPLANLTNLETLD 234
|
90 100
....*....|....*....|....*.
gi 1720355545 283 LANNMLDSIP--GPLPlSLRSLHLQY 306
Cdd:COG4886 235 LSNNQLTDLPelGNLT-NLEELDLSN 259
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
207-306 |
1.75e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 55.71 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHnDALRLLPALQDLILPENQLAALPV----LPSgIEFLDVRLNRLQSsgiqPEAFVALKKLQFLY 282
Cdd:COG4886 183 NLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEplanLTN-LETLDLSNNQLTD----LPELGNLTNLEELD 256
|
90 100
....*....|....*....|....*
gi 1720355545 283 LANNMLDSIPGPLPL-SLRSLHLQY 306
Cdd:COG4886 257 LSNNQLTDLPPLANLtNLKTLDLSN 281
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
207-288 |
6.97e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 6.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLaalpvlpsgiefldvrlnrlqsSGIQPEAFVALKKLQFLYLANN 286
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL----------------------TTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 1720355545 287 ML 288
Cdd:pfam13855 60 RL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
158-310 |
1.28e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 50.08 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 158 QIPEAKISNLT-LPTRTSptSTVAQKTLSPNLTMAVPTTTGllnsqsshAKLRRIDLSGNSISS-------------IHN 223
Cdd:PRK15370 244 QEMELSINRITeLPERLP--SALQSLDLFHNKISCLPENLP--------EELRYLSVYDNSIRTlpahlpsgithlnVQS 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 224 DALRLLPA-----LQDLILPENQLAALPV-LPSGIEFLDVRLNRLQssgIQPEAFVAlkKLQFLYLANNMLDSIPGPLPL 297
Cdd:PRK15370 314 NSLTALPEtlppgLKTLEAGENALTSLPAsLPPELQVLDVSKNQIT---VLPETLPP--TITTLDVSRNALTNLPENLPA 388
|
170
....*....|...
gi 1720355545 298 SLRSLHLQYPLLA 310
Cdd:PRK15370 389 ALQIMQASRNNLV 401
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
207-291 |
2.28e-06 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 49.16 E-value: 2.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIhNDALRLLPALQDLILPENQLAALPVLP--SGIEFLDVRLNRLqsSGIQPEAfvALKKLQFLYLA 284
Cdd:COG4886 206 NLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPELGnlTNLEELDLSNNQL--TDLPPLA--NLTNLKTLDLS 280
|
....*..
gi 1720355545 285 NNMLDSI 291
Cdd:COG4886 281 NNQLTDL 287
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
255-306 |
1.32e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 1.32e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1720355545 255 LDVRLNRLQSsgIQPEAFVALKKLQFLYLANNMLDSIPG----PLPlSLRSLHLQY 306
Cdd:pfam13855 6 LDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPgafsGLP-SLRYLDLSG 58
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
117-306 |
9.20e-04 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 40.69 E-value: 9.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 117 QSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKISNLTLPTRTSPTSTVAQKTLSPNLTMAVPTTT 196
Cdd:COG4886 7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 197 GLLNSQSSHAKLRRIDLSGNsissihnDALRLLPALQDLILPENQLAALPvlpsgiefldvrlnrlqssgiqpEAFVALK 276
Cdd:COG4886 87 LGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLP-----------------------EELANLT 136
|
170 180 190
....*....|....*....|....*....|..
gi 1720355545 277 KLQFLYLANNMLDSIPGPLPL--SLRSLHLQY 306
Cdd:COG4886 137 NLKELDLSNNQLTDLPEPLGNltNLKSLDLSN 168
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
207-305 |
9.68e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 39.77 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHNdaLRLLPALQDLILpENQlaalpVLPSG--IEF--------------LDVRLNRLQSsgiqPE 270
Cdd:cd21340 69 NLKKLYLGGNRISVVEG--LENLTNLEELHI-ENQ-----RLPPGekLTFdprslaalsnslrvLNISGNNIDS----LE 136
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1720355545 271 AFVALKKLQFLYLANNMLDSIPGPLPL-----SLRSLHLQ 305
Cdd:cd21340 137 PLAPLRNLEQLDASNNQISDLEELLDLlsswpSLRELDLT 176
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
131-310 |
1.14e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 40.92 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 131 GNHTLSIEDYNEV----IDLSNYEELADYGDQiPEAKISNLTLPTRTSPTSTVAQKTLSPNLTMAVPTTTGLlNSQSSHA 206
Cdd:PRK15387 116 GNYTVNCQGYSEThrltLDTAQGEEGTGHAEG-ASGTFRTSFLPATTAPQTPAEYDAVWSAWRRAAPAEESR-GRAAVVQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 207 KLRRIDLSGNSISSIHNDALRLLP-----ALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVAL------ 275
Cdd:PRK15387 194 KMRACLNNGNAVLNVGESGLTTLPdclpaHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELsifsnp 273
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1720355545 276 --------KKLQFLYLANNMLDSIPgPLPLSLRSLHLQYPLLA 310
Cdd:PRK15387 274 lthlpalpSGLCKLWIFGNQLTSLP-VLPPGLQELSVSDNQLA 315
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
208-275 |
4.67e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 38.99 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 208 LRRIDLSGNSISSI------------HNDALRLLPAL----QDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEA 271
Cdd:PRK15387 344 LQELSVSDNQLASLptlpselyklwaYNNRLTSLPALpsglKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPMLPSG 423
|
....
gi 1720355545 272 FVAL 275
Cdd:PRK15387 424 LLSL 427
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
215-302 |
4.88e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 38.99 E-value: 4.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 215 GNSISSIHndalRLLPALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAfvalkkLQFLYLANNMLDSIPgP 294
Cdd:PRK15387 291 GNQLTSLP----VLPPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPSG------LQELSVSDNQLASLP-T 359
|
....*...
gi 1720355545 295 LPLSLRSL 302
Cdd:PRK15387 360 LPSELYKL 367
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
208-302 |
5.56e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 38.60 E-value: 5.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355545 208 LRRIDLSGNSISSI------------HNDALRLLP----ALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEA 271
Cdd:PRK15387 304 LQELSVSDNQLASLpalpselcklwaYNNQLTSLPtlpsGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSG 383
|
90 100 110
....*....|....*....|....*....|.
gi 1720355545 272 fvalkkLQFLYLANNMLDSIPgPLPLSLRSL 302
Cdd:PRK15387 384 ------LKELIVSGNRLTSLP-VLPSELKEL 407
|
|
|