|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
128-758 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 1126.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 128 PEYQRVTISGDYCAGITVEDYEQAAKSLAKALMIREKYArlayhrFPRTTAQYLAH-QGE-SVPLEEGLPDFHPPPLPQE 205
Cdd:pfam19326 1 PEVQRVTISGDYKLGVPTEDLEEAYKSLAECLEIREKYM------FPETTAPYLKSvQGEdSTPKENDEPVFHPPPKKGE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 206 DPYCLDDAPPNLGYLVRMHGGVLFVYDNQTMLErqepHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFS 285
Cdd:pfam19326 75 DPYELFNFPPDLGYHLRMQDGVVHVYANKDALE----DSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 286 LHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDP 365
Cdd:pfam19326 151 LHLMLNEMKELKAQKSNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 366 YDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRS 445
Cdd:pfam19326 231 YDLSVDTLDVHADRDTFHRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 446 PKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSV 525
Cdd:pfam19326 311 PDEWDKLASWIVDNKVYSPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 526 DDESKHSDHMFSdKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNI 605
Cdd:pfam19326 391 DDESKPERRMFR-KSPKPALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGI 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 606 SHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVW 685
Cdd:pfam19326 470 SHGILLRKSPVLQYLYYLAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVW 549
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176653 686 KLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKS 758
Cdd:pfam19326 550 KLSACDMCELARNSVLQSGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALISDAVKS 622
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
146-752 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 1084.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 146 EDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQYLAHQG--ESVPLEEGLPDFHPPPLPQEDPYCLDDAPP--NLGYLV 221
Cdd:TIGR01429 1 EDLAEAAKSLAKALMLREKYARLAYHRFPDTTAQYLSHQGypESVPLEEGLPDFHPPPDPQEDPYCLDDDAPpiELGYLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 222 RMHGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKS 301
Cdd:TIGR01429 81 RMHGGVLFVYDNDTMLERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQKS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 302 NPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQT 381
Cdd:TIGR01429 161 VPHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADRNT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 382 FHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKV 461
Cdd:TIGR01429 241 FHRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 462 YSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSP 541
Cdd:TIGR01429 321 FSPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRKFP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 542 SPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLY 621
Cdd:TIGR01429 401 SPDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 622 YLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVL 701
Cdd:TIGR01429 481 YLTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVL 560
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1907176653 702 QSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFL 752
Cdd:TIGR01429 561 QSGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
253-749 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 896.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 253 YIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFI 332
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 333 KHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLG 412
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 413 GEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKML 492
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 493 ENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLR 572
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESK-SERRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLH 652
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 653 KGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTN 732
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 1907176653 733 VAQIRMAFRYETLCNEL 749
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
147-761 |
0e+00 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 683.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 147 DYEQAAKSLAKALMIREKYArlayhrFPRTTAqylahqgesvPLEEGLPDFHPPPLPQEDPYCLDDAPPNLGYLvRMHGG 226
Cdd:PLN02768 239 DEVEAYKVLQECLELRKRYV------FREEVA----------PWEKEIISDPSTPKPNPNPFSYTPEGKSDHYF-EMQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 227 VLFVYDNQTMLERQephsLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRD 306
Cdd:PLN02768 302 VVHVYANKDSKEEL----FPVADATTFFTDLHHILRVIAAGNIRTLCHHRLNLLEQKFNLHLMLNADREFLAQKSAPHRD 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 307 FYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFD 386
Cdd:PLN02768 378 FYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGYDLNVDLLDVHADKSTFHRFD 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 387 KFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNM 466
Cdd:PLN02768 458 KFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNELYSENV 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 467 RWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK----HSDHMfsdksPS 542
Cdd:PLN02768 538 VWLIQLPRLYNVYKEMGIVTSFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVDDESKperrPTKHM-----PT 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 543 PDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 622
Cdd:PLN02768 613 PAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIAHGINLRKSPVLQYLYY 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 623 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQ 702
Cdd:PLN02768 693 LAQIGLAMSPLSNNSLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSSCDLCEIARNSVYQ 772
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176653 703 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELS--FLSDAMKSEEI 761
Cdd:PLN02768 773 SGFSHALKSHWIGKEYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQqvYLGKAKIPEEV 833
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
573-716 |
2.16e-18 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 87.06 E-value: 2.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKNP 646
Cdd:COG1816 178 REAGL---HLTAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAL--VARLAdrGIPLEVCPTSNVQLgvVPSLAEHP 252
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 647 LREFLHKGLHVSLSTDDPMQFHYTkeaLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQ 716
Cdd:COG1816 253 LRRLLDAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALLAE 319
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
128-758 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 1126.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 128 PEYQRVTISGDYCAGITVEDYEQAAKSLAKALMIREKYArlayhrFPRTTAQYLAH-QGE-SVPLEEGLPDFHPPPLPQE 205
Cdd:pfam19326 1 PEVQRVTISGDYKLGVPTEDLEEAYKSLAECLEIREKYM------FPETTAPYLKSvQGEdSTPKENDEPVFHPPPKKGE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 206 DPYCLDDAPPNLGYLVRMHGGVLFVYDNQTMLErqepHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFS 285
Cdd:pfam19326 75 DPYELFNFPPDLGYHLRMQDGVVHVYANKDALE----DSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 286 LHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDP 365
Cdd:pfam19326 151 LHLMLNEMKELKAQKSNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 366 YDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRS 445
Cdd:pfam19326 231 YDLSVDTLDVHADRDTFHRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 446 PKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSV 525
Cdd:pfam19326 311 PDEWDKLASWIVDNKVYSPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 526 DDESKHSDHMFSdKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNI 605
Cdd:pfam19326 391 DDESKPERRMFR-KSPKPALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGI 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 606 SHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVW 685
Cdd:pfam19326 470 SHGILLRKSPVLQYLYYLAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVW 549
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907176653 686 KLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKS 758
Cdd:pfam19326 550 KLSACDMCELARNSVLQSGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALISDAVKS 622
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
146-752 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 1084.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 146 EDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQYLAHQG--ESVPLEEGLPDFHPPPLPQEDPYCLDDAPP--NLGYLV 221
Cdd:TIGR01429 1 EDLAEAAKSLAKALMLREKYARLAYHRFPDTTAQYLSHQGypESVPLEEGLPDFHPPPDPQEDPYCLDDDAPpiELGYLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 222 RMHGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKS 301
Cdd:TIGR01429 81 RMHGGVLFVYDNDTMLERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQKS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 302 NPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQT 381
Cdd:TIGR01429 161 VPHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADRNT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 382 FHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKV 461
Cdd:TIGR01429 241 FHRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 462 YSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSP 541
Cdd:TIGR01429 321 FSPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRKFP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 542 SPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLY 621
Cdd:TIGR01429 401 SPDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLY 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 622 YLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVL 701
Cdd:TIGR01429 481 YLTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVL 560
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1907176653 702 QSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFL 752
Cdd:TIGR01429 561 QSGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
253-749 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 896.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 253 YIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFI 332
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 333 KHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLG 412
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 413 GEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKML 492
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 493 ENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLR 572
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESK-SERRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLH 652
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 653 KGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTN 732
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 1907176653 733 VAQIRMAFRYETLCNEL 749
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
147-761 |
0e+00 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 683.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 147 DYEQAAKSLAKALMIREKYArlayhrFPRTTAqylahqgesvPLEEGLPDFHPPPLPQEDPYCLDDAPPNLGYLvRMHGG 226
Cdd:PLN02768 239 DEVEAYKVLQECLELRKRYV------FREEVA----------PWEKEIISDPSTPKPNPNPFSYTPEGKSDHYF-EMQDG 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 227 VLFVYDNQTMLERQephsLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRD 306
Cdd:PLN02768 302 VVHVYANKDSKEEL----FPVADATTFFTDLHHILRVIAAGNIRTLCHHRLNLLEQKFNLHLMLNADREFLAQKSAPHRD 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 307 FYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFD 386
Cdd:PLN02768 378 FYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGYDLNVDLLDVHADKSTFHRFD 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 387 KFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNM 466
Cdd:PLN02768 458 KFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNELYSENV 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 467 RWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK----HSDHMfsdksPS 542
Cdd:PLN02768 538 VWLIQLPRLYNVYKEMGIVTSFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVDDESKperrPTKHM-----PT 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 543 PDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 622
Cdd:PLN02768 613 PAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIAHGINLRKSPVLQYLYY 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 623 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQ 702
Cdd:PLN02768 693 LAQIGLAMSPLSNNSLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSSCDLCEIARNSVYQ 772
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907176653 703 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELS--FLSDAMKSEEI 761
Cdd:PLN02768 773 SGFSHALKSHWIGKEYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQqvYLGKAKIPEEV 833
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
189-753 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 676.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 189 PLEEGLPDfHPPPLPQEDPYCLDDAPPNlGYLVRMHGGVLFVYDNQTMLErqepHSLPYPDLETYIVDMSHILALITDGP 268
Cdd:PLN03055 33 PWRKGIFE-SSTSKPNPDPFRYEPEPPS-QHVFRMVDGVMHVYAPDDAKE----ELFPVPDATTFFTDMHRILRIVSLGN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 269 TKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKL 348
Cdd:PLN03055 107 VRTFCHHRLKLLEQKFSLHLMLNADREFLAQKSAPHRDFYNVRKVDTHVHHSSCMNQKHLLRFIKSKLRKEPDEVVIFRD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 349 GRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELE 428
Cdd:PLN03055 187 GKYLTLREVFESLDLTGYDLNVDLLDVHADKNTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKEVFSDLE 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 429 DSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQD 508
Cdd:PLN03055 267 ASKYQMAEYRISIYGRKQSEWDQLASWIVNNRLYSENVVWLIQLPRLYNVYKEMGIVQSFQQILDNIFKPLFEVTVDPSS 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 509 HRELHLFLKYVTGFDSVDDESK----HSDHMfsdksPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRP 584
Cdd:PLN03055 347 HPQLHVFLKMVVGFDMVDDESKperrPTKHM-----QTPEQWDIPFNPAYSYWAYYVYANLYTLNKLRESKGLNTIKFRP 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 585 HCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDP 664
Cdd:PLN03055 422 HAGEAGDIDHLAAAFLLAHNIAHGNNLRKSPGLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFARGLNVSLSTDDP 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 665 MQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYET 744
Cdd:PLN03055 502 LQIHLTKEPLVEEYSIAAQVWKLSSCDLCEIARNSVLQSGFPHASKKHWVGDNYWLRGPAGNDIHKTNVPHMRVEFRHEV 581
|
....*....
gi 1907176653 745 LCNELSFLS 753
Cdd:PLN03055 582 WKEELQYVF 590
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
242-753 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 561.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 242 PHSLPypDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEF--KELKSNPHRDFYNVRKVDTHIHA 319
Cdd:PTZ00310 776 PRFLP--TLTEFIRDLSELRDICSSVEVKRLATKRLENLEHKFRLHLALNHSNEAgtTEERESSNRDFYQAYKVDTHIHM 853
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 320 AACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPyDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASE 399
Cdd:PTZ00310 854 AAGMTARQLLEFVVDKLLESGDDIAFKRGDHIVTLGQLFSKYGITP-NLTVDQLNVQADHTLFERFDNFNSKYNPMENPD 932
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 400 LRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIF 479
Cdd:PTZ00310 933 LRSLLLKTDNFMKGRYFAELIKDVFEQYSRDRFTYAENRLSIYGINVKEWDDLAHWFDTHGMASKHNKWMIQVPRVYKVF 1012
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 480 RSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPSPdlWTSEQNPPYSYYLY 559
Cdd:PTZ00310 1013 RAQNVIGSFGQYLDNIFQPLWEASLHPSKHPKFHYFLNHVSGFDSVDNEAT-IDLPFTDVSPWA--WTSVENPPYNYYLY 1089
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 560 YMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLF 639
Cdd:PTZ00310 1090 YLYANIRTLNEFRASRGFSTFALRPHCGESGSMDHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALF 1169
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 640 LEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYY 719
Cdd:PTZ00310 1170 LAFLENPFPVFFHRGLNVSLSTDDPLMFHQTQEPLIEEYSIAARVWGLSLNDLCEIARNSVLQSGFDAAFKRNAIGDRWY 1249
|
490 500 510
....*....|....*....|....*....|....
gi 1907176653 720 KEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLS 753
Cdd:PTZ00310 1250 LSSSLGNDSLRTHLSDIRVAFRFETYHTELNFLE 1283
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
128-754 |
7.51e-91 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 311.74 E-value: 7.51e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 128 PEYQRVTISGDYcAGItveDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQylahqgesvpleeglpDFHPPPLPQEDP 207
Cdd:PTZ00310 63 STMFRVVIDGDD-GGV---DMRKVHGRIAAAIRVRQLYKPTDTKVPEGEREQ----------------PSDSTPMPSLVT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 208 YCLDDappnlgylvrmhgGVLFVYDNQTmlerqepHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLH 287
Cdd:PTZ00310 123 IVQRD-------------GVYRFSGMDT-------SVVLPPPWEQYVRDVQAVYLTVGNGPCLSACRHRLTIIQERSRMF 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 288 EMLN-EMSEfkelKSNPHRD---FYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHM 363
Cdd:PTZ00310 183 FLLNaEIEE----RADLYKAggvFSPCTKVDNAVLLSTSVDAQELLEFVVTTYREQPRAPLRLRDGSNSTLREYLEAHGV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 364 -DPYDLTVDSLDVHA--GRQTFHRFDKFNSKyNPVGA--SELRDLYLKTENYLGGEYFARMVKEvaRELEDSKYQYSEPR 438
Cdd:PTZ00310 259 rDPRELTVEGLGWQPtkYRNKYGQYDLFDAK-NPMGAlgAELRQSFLSLHGNLCGKLLRRELER--REYQKQQPQATEYS 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 439 LSIYGRSPKEWSSLARWFIQHKVYS-PNMRWIIQVpriydifRSKKLLPN--------FGKMLENIFLPLFKATINPQDH 509
Cdd:PTZ00310 336 LPLYGHHPEELTDLAEWVRRQGFGPfSRNRWILAI-------SFKELGPFqvpsscttVQDQLDNIFLPLFKATLCPSDP 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 510 R--ELHLFLKYVTGFdSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCG 587
Cdd:PTZ00310 409 QwsDVAWLLCQVGGL-QILTHAVVRSEDFDETAPDPDQVPYTAKCSDLYYFYYVYANLAVLNSLRKRKGLNTLQLRPSGE 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 588 EAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSL-FLEYSKNPLREFLHKGLHVSLSTDDPMQ 666
Cdd:PTZ00310 488 KAPAYDQLISSYLLGDVITRATSIADYPVLQYLCGLHRVGLTVSPLRDHALsITAYFDHPLPKFLHRCLRVSISTSDPLY 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 667 FHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKeGPEGNDIRKTNVAQIRMAFRYETLC 746
Cdd:PTZ00310 568 FHHHSQPLIEEYATAMKLFSLSPLDTTELARNSVLNSSFPPEVKQQWLGERFQL-GVEGNDFERSGVTNYRLAFREEAWA 646
|
....*...
gi 1907176653 747 NELSFLSD 754
Cdd:PTZ00310 647 LEEALLND 654
|
|
| ADA_AMPD |
cd00443 |
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic ... |
311-717 |
9.17e-56 |
|
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase catalyzes a similar reaction leading to the hydrolytic removal of an amino group at the 6 position of the adenine nucleotide ring, a branch point in the adenylate catabolic pathway.
Pssm-ID: 238250 Cd Length: 305 Bit Score: 193.72 E-value: 9.17e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 311 RKVDTHIHAAACMNQKHLLRFIKhtyqtepdrtvaeklgrkitlrqvfdslhmdpydltvdsldvhagrqtfhrfdkfns 390
Cdd:cd00443 2 PKVELHAHLSGSISPETLLELIK--------------------------------------------------------- 24
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 391 kynpvgaSELRDLYLKTENYL-GGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSP-KEWSSLARWFIQHKVYSPNMRW 468
Cdd:cd00443 25 -------KEFFEKFLLVHNLLqKGEALARALKEVIEEFAEDNVQYLELRTTPRLLETeKGLTKEQYWLLVIEGISEAKQW 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 469 --IIQVPRIYDIFRSKkllpnfgkmleniflPLFKATINPQDHRELHLFLK-YVTGFDSVDDESKHSDhmfsdksPSPDL 545
Cdd:cd00443 98 fpPIKVRLILSVDRRG---------------PYVQNYLVASEILELAKFLSnYVVGIDLVGDESKGEN-------PLRDF 155
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 546 wtseqnppysyylyymyanIMVLNNLRRergLSTFLFRPHCGEAGSITHLVSAF-LTADNISHGLLLKKSPVLQYLYYLA 624
Cdd:cd00443 156 -------------------YSYYEYARR---LGLLGLTLHCGETGNREELLQALlLLPDRIGHGIFLLKHPELIYLVKLR 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 625 QIPIAMSPLSNNSLFL--EYSKNPLREFLHKGLHVSLSTDDPMQFHYTkeaLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 702
Cdd:cd00443 214 NIPIEVCPTSNVVLGTvqSYEKHPFMRFFKAGLPVSLSTDDPGIFGTS---LSEEYSLAAKTFGLTFEDLCELNRNSVLS 290
|
410
....*....|....*
gi 1907176653 703 SGLSHQEKQKFLGQN 717
Cdd:cd00443 291 SFAKDEEKKSLLEVL 305
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
573-716 |
2.16e-18 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 87.06 E-value: 2.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKNP 646
Cdd:COG1816 178 REAGL---HLTAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAL--VARLAdrGIPLEVCPTSNVQLgvVPSLAEHP 252
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 647 LREFLHKGLHVSLSTDDPMQFHYTkeaLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQ 716
Cdd:COG1816 253 LRRLLDAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALLAE 319
|
|
| PRK09358 |
PRK09358 |
adenosine deaminase; Provisional |
573-714 |
8.56e-18 |
|
adenosine deaminase; Provisional
Pssm-ID: 236480 Cd Length: 340 Bit Score: 85.61 E-value: 8.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLstfLFRPHCGEAG---SITHLVsAFLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKN 645
Cdd:PRK09358 192 RDAGL---RLTAHAGEAGgpeSIWEAL-DELGAERIGHGVRAIEDPAL--MARLAdrRIPLEVCPTSNVQTgaVPSLAEH 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176653 646 PLREFLHKGLHVSLSTDDPMQFHYTkeaLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 714
Cdd:PRK09358 266 PLKTLLDAGVRVTINTDDPLVFGTT---LTEEYEALAEAFGLSDEDLAQLARNALEAAFLSEEEKAALL 331
|
|
| ADA |
cd01320 |
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the ... |
573-714 |
1.01e-16 |
|
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.
Pssm-ID: 238645 Cd Length: 325 Bit Score: 81.87 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLStflFRPHCGEAGSITHLVSAF--LTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNnsLFL----EYSK 644
Cdd:cd01320 183 REAGLR---LTAHAGEAGGPESVRDALdlLGAERIGHGIRAIEDPEL--VKRLAerNIPLEVCPTSN--VQTgavkSLAE 255
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 645 NPLREFLHKGLHVSLSTDDPMQFHYTkeaLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 714
Cdd:cd01320 256 HPLRELLDAGVKVTINTDDPTVFGTY---LTDEYELLAEAFGLTEEELKKLARNAVEASFLSEEEKAELL 322
|
|
| A_deaminase |
pfam00962 |
Adenosine deaminase; |
573-714 |
6.25e-11 |
|
Adenosine deaminase;
Pssm-ID: 425964 Cd Length: 330 Bit Score: 64.37 E-value: 6.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSN--NSLFLEYSKNP 646
Cdd:pfam00962 185 RDAGL---HLTVHAGEAGGPQSVWEAldDLGAERIGHGVRSAEDPRL--LDRLAdrQIPLEICPTSNvqTGAVASLAEHP 259
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907176653 647 LREFLHKGLHVSLSTDDPMQFhytKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 714
Cdd:pfam00962 260 LKTFLRAGVPVSLNTDDPLMF---GSDLLDEYQVAKRAPGFDEEELARLAKNAVKGSFLPADEKRALL 324
|
|
| metallo-dependent_hydrolases |
cd01292 |
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a ... |
581-696 |
1.87e-10 |
|
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The family includes urease alpha, adenosine deaminase, phosphotriesterase dihydroorotases, allantoinases, hydantoinases, AMP-, adenine and cytosine deaminases, imidazolonepropionase, aryldialkylphosphatase, chlorohydrolases, formylmethanofuran dehydrogenases and others.
Pssm-ID: 238617 [Multi-domain] Cd Length: 275 Bit Score: 62.35 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 581 LFRPHCGEAGSITHLVSAFLTAD------NISHGLLLkkSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSK-NPLREFLHK 653
Cdd:cd01292 148 PVVIHAGELPDPTRALEDLVALLrlggrvVIGHVSHL--DPELLELLKEAGVSLEVCPLSNYLLGRDGEGaEALRRLLEL 225
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1907176653 654 GLHVSLSTDDPmqFHYTKEALMEEYAIAAQVWKL--STCDLCEIA 696
Cdd:cd01292 226 GIRVTLGTDGP--PHPLGTDLLALLRLLLKVLRLglSLEEALRLA 268
|
|
| ADGF |
cd01321 |
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors ... |
580-714 |
5.64e-08 |
|
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors with sequence similarty to adenosine deaminase.
Pssm-ID: 238646 Cd Length: 345 Bit Score: 55.36 E-value: 5.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 580 FLFrpHCGE-AGSIT----HLVSA-FLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSN--NSLFLEYSKNPLREFL 651
Cdd:cd01321 197 FFF--HAGEtNGDGTetdeNLVDAlLLNTKRIGHGFALPKHPLLMDLVKKKNIAIEVCPISNqvLGLVSDLRNHPAAALL 274
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907176653 652 HKGLHVSLSTDDPMQFHYTK------EALMeeyAIAAQVWKLSTcdLCEIARNSVLQSGLSHQEKQKFL 714
Cdd:cd01321 275 ARGVPVVISSDDPGFWGAKGlshdfyQAFM---GLAPADAGLRG--LKQLAENSIRYSALSDQEKDEAV 338
|
|
| PTZ00124 |
PTZ00124 |
adenosine deaminase; Provisional |
573-667 |
2.18e-03 |
|
adenosine deaminase; Provisional
Pssm-ID: 173415 Cd Length: 362 Bit Score: 41.00 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907176653 573 RERGLSTFLfrpHCGEAGSITHLVSAF-----LTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNnsLFLEYSKN-- 645
Cdd:PTZ00124 216 REAGVNLTV---HAGEDVTLPNLNTLYsaiqvLKVKRIGHGIRVAESQELIDMVKEKDILLEVCPISN--VLLNNAKSmd 290
|
90 100
....*....|....*....|....
gi 1907176653 646 --PLREFLHKGLHVSLSTDDPMQF 667
Cdd:PTZ00124 291 thPIRKLYDAGVKVSVNSDDPGMF 314
|
|
| |
