NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

613-969

2.93e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.15 E-value: 2.93e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  613 IRTEQQAALQRLREEAETLQKAERASLEQKSRRA------LEQLREQLEAEERSAqaalraekeaekeaallqlrEQLEG 686
Cdd:COG1196    194 ILGELERQLEPLERQAEKAERYRELKEELKELEAellllkLRELEAELEELEAEL--------------------EELEA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  687 ERKEAVAGLEKKHsAELEQlcssLEAKHQEvissLQKKIEGAQQKEEAQLQESLGWAEQRAHqkvhqvteyEQELSSLLR 766
Cdd:COG1196    254 ELEELEAELAELE-AELEE----LRLELEE----LELELEEAQAEEYELLAELARLEQDIAR---------LEERRRELE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  767 DKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRadllghltgELERLRRAHERELESMRQEQDQQLEDLRRRH 846
Cdd:COG1196    316 ERLEELEEELAELEEELEELE-EELEELEEELEEAEEELE---------EAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  847 RDHERKLQDLEvELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEAtatHQHLEEAKKEHTHLLETKQQL 926
Cdd:COG1196    386 EELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEAL 461

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1907196499  927 RRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQ 969
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

600-933

3.95e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 3.95e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  600 AQVQSRTEAFENQIRtEQQAALQRLREEAETLQKAERA--SLEQKSRRALEQLREQLEAEERSAQaalraekeaekeaAL 677
Cdd:TIGR02168  680 EELEEKIEELEEKIA-ELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVE-------------QL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  678 LQLREQLEGERKEAVAGLEKKHsAELEQLCSSLEAkHQEVISSLQKKIEgaQQKEEAQLQESLGWAEQRAHQ----KVHQ 753
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELE-ERLEEAEEELAE-AEAEIEELEAQIE--QLKEELKALREALDELRAELTllneEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  754 VTEYEQELSSLLRDKRQEVEREHERKmdKMKEEHWQEMADARERYEAEERKQRADLLGHLtgeleRLRRAHERELESMRQ 833
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESELEALL-----NERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  834 EqdqqLEDLRRRHRDHERKLQDLEVELSSRTK---DVKARLAQLNVQEENIR--------------KEKQLLLDAQRQAA 896
Cdd:TIGR02168  895 E----LEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQerlseeysltleeaEALENKIEDDEEEA 970

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499  897 LER-------------------EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDL 933
Cdd:TIGR02168  971 RRRlkrlenkikelgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026

PTZ00121

MAEBL; Provisional

592-1142

5.01e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 5.01e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  592 SRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAERASLEQKSRRALEQLREQleaEERSAQAALRAE 668
Cdd:PTZ00121  1103 AKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDArkaEEARKAEDAKRVEIARKAEDARKAE---EARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  669 KEAEKeaalLQLREQLEGERKEAVAGLEKKHSAELEQLCSslEAKHQEVisslQKKIEGAQQKEEAQLQESlgwaEQRAH 748
Cdd:PTZ00121  1180 AARKA----EEVRKAEELRKAEDARKAEAARKAEEERKAE--EARKAED----AKKAEAVKKAEEAKKDAE----EAKKA 1245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  749 QKV---HQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMAD----ARERYEAEERKQRAdllghltgelERLR 821
Cdd:PTZ00121  1246 EEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADeakkAEEKKKADEAKKKA----------EEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  822 RAHerELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQlLLDAQRQAALEREE 901
Cdd:PTZ00121  1316 KAD--EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK-KADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  902 ATATHQHLEEAKKEHTHlLETKQQLRRTIDDLRVRRVELEsqvdllqaQSQRLQKhlsslEAEVQRKQDVLKEMAAEmnA 981
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEKK--------KADEAKK-----KAEEAKKADEAKKKAEE--A 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  982 SPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGvAVRNAKEflVRQTRSMRRRQTALKAAQQ 1061
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE-AKKKADE--AKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1062 HWRHELASAQEV---DEDLPGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEvsdEDTLKGS 1138
Cdd:PTZ00121  1534 KKADEAKKAEEKkkaDELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE---EKKMKAE 1610


                   ....
gi 1907196499 1139 SIKK 1142
Cdd:PTZ00121  1611 EAKK 1614

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

625-969

1.90e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 65.53 E-value: 1.90e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  625 REEAETLQKAERASLEQKSRRALEQL--REQLEAEERSAQAALRAEKEAEKEaallQLREQLEGERkeavaglekkhsaE 702
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAE----QERMAMERER-------------E 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  703 LEQLcsSLEAKHQEVISSLQKKIegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSsLLRDKRQEVEREHERKMDK 782
Cdd:pfam17380  350 LERI--RQEERKRELERIRQEEI--AMEISRMRELERLQMERQQKNERVRQELEAARKVK-ILEEERQRKIQQQKVEMEQ 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  783 MkeehwqemadareRYEAEERKQRadllghltgELERLRRAHERELESMRQE-QDQQLEDLRRRHRDHERKLQDLEVEls 861
Cdd:pfam17380  425 I-------------RAEQEEARQR---------EVRRLEEERAREMERVRLEeQERQQQVERLRQQEEERKRKKLELE-- 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  862 sRTKDVKARLAQLN--VQEENIRKEKQLLLDAQRQAAL------EREEATATHQHLEEAKKEHTHLLETKQqlRRTIDDL 933
Cdd:pfam17380  481 -KEKRDRKRAEEQRrkILEKELEERKQAMIEEERKRKLlekemeERQKAIYEEERRREAEEERRKQQEMEE--RRRIQEQ 557

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1907196499  934 RVRRVELESQVDLLQAQSQRLQKhlsSLEAEVQRKQ 969
Cdd:pfam17380  558 MRKATEERSRLEAMEREREMMRQ---IVESEKARAE 590

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

891-1118

2.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.93e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  891 AQRQAALE--REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 968
Cdd:COG4942     23 AEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  969 QDVLKEMAAE---MNASPHPEPGLHIEDlrkSLDTNKNQEVssslslskeeidlsMESVRQFLSAEGVAVRNAKEFLVRQ 1045
Cdd:COG4942    103 KEELAELLRAlyrLGRQPPLALLLSPED---FLDAVRRLQY--------------LKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499 1046 TRS---MRRRQTALKAAQQHWRHELASAQEVDEDLpgtevLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKL 1118
Cdd:COG4942    166 RAEleaERAELEALLAELEEERAALEALKAERQKL-----LARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.03e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.03e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 1907196499   58 LPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

825-1136

3.49e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.53 E-value: 3.49e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  825 ERELESMRQEQDQQLEDLRRRhrdherkLQDLEVELSS----------RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ 894
Cdd:TIGR02169  662 PRGGILFSRSEPAELQRLRER-------LEGLKRELSSlqselrrienRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  895 AALE----REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESqvDLLQAQSQRLQKHLSSLEAEVQRKQD 970
Cdd:TIGR02169  735 LKERleelEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEA 812

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  971 VLKEMAAEMNASpHPEPGL------HIEDLRKSLDTNKN--QEVSSSLSLSKEEIDLSMESVRQF---LSAEGVAVRNAK 1039
Cdd:TIGR02169  813 RLREIEQKLNRL-TLEKEYlekeiqELQEQRIDLKEQIKsiEKEIENLNGKKEELEEELEELEAAlrdLESRLGDLKKER 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1040 EFLVRQTRSMRRRQTALKAAQQHWRH---------------------ELASAQEVDEDLPGTEVLGNMRKNLNEETRHL- 1097
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKrlselkaklealeeelseiedPKGEDEEIPEEELSLEDVQAELQRVEEEIRALe 971

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1907196499 1098 -------DEMKSAMRKgHDLLKKKEEKLIQLESSLQEEVSDEDTLK 1136
Cdd:TIGR02169  972 pvnmlaiQEYEEVLKR-LDELKEKRAKLEEERKAILERIEEYEKKK 1016

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

3.80e-05

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other peptide recognition proteins such as antibodies and receptors; WW domains have a single groove formed by a conserved Trp and Tyr which recognizes a pair of residues of the sequence X-Pro; variable loops and neighboring domains confer specificity in this domain; there are five distinct groups based on binding: 1) PPXY motifs 2) the PPLP motif; 3) PGM motifs; 4) PSP or PTP motifs; 5) PR motifs.

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 41.74 E-value: 3.80e-05

                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907196499   59 PKGWKPCQNITGDLYYFNFDTGQSIWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.13e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 39.89 E-value: 2.13e-04

                            10        20        30
                    ....*....|....*....|....*....|.
gi 1907196499    57 PLPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

817-969

3.18e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 44.62 E-value: 3.18e-04

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499   817 LERLRRAHERELESMRQEqDQQLedlrrrhRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRqaa 896
Cdd:smart00787  142 LEGLKEGLDENLEGLKED-YKLL-------MKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAK--- 210

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907196499   897 lerEEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDllQAQSQRLQ------KHLSSLEAEVQRKQ 969
Cdd:smart00787  211 ---EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIA--EAEKKLEQcrgftfKEIEKLKEQLKLLQ 284

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

607-726

1.55e-03

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.18 E-value: 1.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  607 EAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRaekeaekeaallQLREQLE 685
Cdd:cd16269    180 EAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEqQRELEQKLEDQERSYEEHLR------------QLKEKME 247

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1907196499  686 GERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIE 726
Cdd:cd16269    248 EERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEEIR 288

PLN02939

transferase, transferring glycosyl groups

821-1127

1.58e-03

transferase, transferring glycosyl groups

Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 1.58e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  821 RRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------RKEKQLLLDAQR 893
Cdd:PLN02939    36 RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDhnrasmqRDEAIAAIDNEQ 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  894 QAALEREEATATHQhLEEakkehthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK 973
Cdd:PLN02939   116 QTNSKDGEQLSDFQ-LED-------LVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  974 eMAAEMNAspHPE-PGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVR-----QFLSAEGVAVRNAKEFLVRqtr 1047
Cdd:PLN02939   188 -LAAQEKI--HVEiLEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLlkddiQFLKAELIEVAETEERVFK--- 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1048 sMRRRQTALKAAQQHWRHELASAQE---------VDEDLPGTEVLGNMrknLNEETRHLDEMKSAMRKGHDLLKKKEEkl 1118
Cdd:PLN02939   262 -LEKERSLLDASLRELESKFIVAQEdvsklsplqYDCWWEKVENLQDL---LDRATNQVEKAALVLDQNQDLRDKVDK-- 335


                   ....*....
gi 1907196499 1119 iqLESSLQE 1127
Cdd:PLN02939   336 --LEASLKE 342

growth_prot_Scy

NF041483

polarized growth protein Scy;

599-955

4.11e-03

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 41.74 E-value: 4.11e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAE--RASLEQKSRRALEQLReqleAEERSAQAALRAEKEAEK 673
Cdd:NF041483   116 RLQAELHTEAVQRRQQLDQELAERRQTVEShvnENVAWAEqlRARTESQARRLLDESR----AEAEQALAAARAEAERLA 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  674 EAALLQLREQLEGERKEAVAGLeKKHSAELEQLCSSLEAKHQEVIS-SLQKKIEGAQQKEEA--QLQESLGWAEQRAhqk 750
Cdd:NF041483   192 EEARQRLGSEAESARAEAEAIL-RRARKDAERLLNAASTQAQEATDhAEQLRSSTAAESDQArrQAAELSRAAEQRM--- 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  751 vhqvteyeQELSSLLRDKRQEVerehERKMDKMKEEHWQEMADARERYEAEER---KQRADLLGHLTGELERLRRAHERE 827
Cdd:NF041483   268 --------QEAEEALREARAEA----EKVVAEAKEAAAKQLASAESANEQRTRtakEEIARLVGEATKEAEALKAEAEQA 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  828 LESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRT---------KDVKARLAQLNVQEENIRKEkqllldAQRQAALE 898
Cdd:NF041483   336 LADARAEAEKLVAEAAEKARTVAAEDTAAQLAKAARTaeevltkasEDAKATTRAAAEEAERIRRE------AEAEADRL 409

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  899 REEATATHQHLEEAKKEHThlletkqqlrrtiDDLRVRRVELESQVDLLQAQSQRLQ 955
Cdd:NF041483   410 RGEAADQAEQLKGAAKDDT-------------KEYRAKTVELQEEARRLRGEAEQLR 453

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

613-969

2.93e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.15 E-value: 2.93e-18

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  613 IRTEQQAALQRLREEAETLQKAERASLEQKSRRA------LEQLREQLEAEERSAqaalraekeaekeaallqlrEQLEG 686
Cdd:COG1196    194 ILGELERQLEPLERQAEKAERYRELKEELKELEAellllkLRELEAELEELEAEL--------------------EELEA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  687 ERKEAVAGLEKKHsAELEQlcssLEAKHQEvissLQKKIEGAQQKEEAQLQESLGWAEQRAHqkvhqvteyEQELSSLLR 766
Cdd:COG1196    254 ELEELEAELAELE-AELEE----LRLELEE----LELELEEAQAEEYELLAELARLEQDIAR---------LEERRRELE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  767 DKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRadllghltgELERLRRAHERELESMRQEQDQQLEDLRRRH 846
Cdd:COG1196    316 ERLEELEEELAELEEELEELE-EELEELEEELEEAEEELE---------EAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  847 RDHERKLQDLEvELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEAtatHQHLEEAKKEHTHLLETKQQL 926
Cdd:COG1196    386 EELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEAL 461

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1907196499  927 RRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQ 969
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

558-1004

3.53e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 3.53e-16

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  558 QQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERA 637
Cdd:COG1196    319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAEL 398

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  638 SLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEV 717
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  718 ISSLQKKIEGAQQKEEAQLQ-------ESLGWAEQRAHQKVHQVT-----------EYEQELSSLLRDKRQEVEREHERK 779
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEaeadyegFLEGVKAALLLAGLRGLAgavavligveaAYEAALEAALAAALQNIVVEDDEV 558

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  780 MDKMKEEHWQEMADARERY---EAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 856
Cdd:COG1196    559 AAAAIEYLKAAKAGRATFLpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  857 EVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRtiddlrvr 936
Cdd:COG1196    639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA-------- 710

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907196499  937 rvELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPgLHIEDLRKSLDTNKNQ 1004
Cdd:COG1196    711 --EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP-PDLEELERELERLERE 775

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

558-1100

1.95e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 81.91 E-value: 1.95e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  558 QQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIR------TEQQAALQRLREEAETL 631
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEelelelEEAQAEEYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  632 QKAERASLEQKSRRA-----LEQLREQLEAEERSAQAALraEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQL 706
Cdd:COG1196    301 EQDIARLEERRRELEerleeLEEELAELEEELEELEEEL--EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  707 cSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLgwAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEE 786
Cdd:COG1196    379 -EELEELAEELLEALRAAAELAAQLEELEEAEEA--LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  787 HWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKD 866
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  867 VK--------ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRtiDDLRVRRV 938
Cdd:COG1196    536 YEaaleaalaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA--SDLREADA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  939 ELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEID 1018
Cdd:COG1196    614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1019 LSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQH----WRHELASAQEVDEDLPGTEVLGNMRKNLNEET 1094
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELleelLEEEELLEEEALEELPEPPDLEELERELERLE 773


                   ....*.
gi 1907196499 1095 RHLDEM 1100
Cdd:COG1196    774 REIEAL 779

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

600-933

3.95e-15

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 3.95e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  600 AQVQSRTEAFENQIRtEQQAALQRLREEAETLQKAERA--SLEQKSRRALEQLREQLEAEERSAQaalraekeaekeaAL 677
Cdd:TIGR02168  680 EELEEKIEELEEKIA-ELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVE-------------QL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  678 LQLREQLEGERKEAVAGLEKKHsAELEQLCSSLEAkHQEVISSLQKKIEgaQQKEEAQLQESLGWAEQRAHQ----KVHQ 753
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELE-ERLEEAEEELAE-AEAEIEELEAQIE--QLKEELKALREALDELRAELTllneEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  754 VTEYEQELSSLLRDKRQEVEREHERKmdKMKEEHWQEMADARERYEAEERKQRADLLGHLtgeleRLRRAHERELESMRQ 833
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESELEALL-----NERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  834 EqdqqLEDLRRRHRDHERKLQDLEVELSSRTK---DVKARLAQLNVQEENIR--------------KEKQLLLDAQRQAA 896
Cdd:TIGR02168  895 E----LEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQerlseeysltleeaEALENKIEDDEEEA 970

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499  897 LER-------------------EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDL 933
Cdd:TIGR02168  971 RRRlkrlenkikelgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026

PTZ00121

MAEBL; Provisional

592-1142

5.01e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.41 E-value: 5.01e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  592 SRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAERASLEQKSRRALEQLREQleaEERSAQAALRAE 668
Cdd:PTZ00121  1103 AKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDArkaEEARKAEDAKRVEIARKAEDARKAE---EARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  669 KEAEKeaalLQLREQLEGERKEAVAGLEKKHSAELEQLCSslEAKHQEVisslQKKIEGAQQKEEAQLQESlgwaEQRAH 748
Cdd:PTZ00121  1180 AARKA----EEVRKAEELRKAEDARKAEAARKAEEERKAE--EARKAED----AKKAEAVKKAEEAKKDAE----EAKKA 1245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  749 QKV---HQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMAD----ARERYEAEERKQRAdllghltgelERLR 821
Cdd:PTZ00121  1246 EEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADeakkAEEKKKADEAKKKA----------EEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  822 RAHerELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQlLLDAQRQAALEREE 901
Cdd:PTZ00121  1316 KAD--EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK-KADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  902 ATATHQHLEEAKKEHTHlLETKQQLRRTIDDLRVRRVELEsqvdllqaQSQRLQKhlsslEAEVQRKQDVLKEMAAEmnA 981
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEKK--------KADEAKK-----KAEEAKKADEAKKKAEE--A 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  982 SPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGvAVRNAKEflVRQTRSMRRRQTALKAAQQ 1061
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAE-AKKKADE--AKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1062 HWRHELASAQEV---DEDLPGTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEvsdEDTLKGS 1138
Cdd:PTZ00121  1534 KKADEAKKAEEKkkaDELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE---EKKMKAE 1610


                   ....
gi 1907196499 1139 SIKK 1142
Cdd:PTZ00121  1611 EAKK 1614

PTZ00121

MAEBL; Provisional

592-1149

1.19e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 73.25 E-value: 1.19e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  592 SRRLVCLRAQVQSRTEAFEnqiRTEQQAALQRLREeAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEA 671
Cdd:PTZ00121  1266 ARRQAAIKAEEARKADELK---KAEEKKKADEAKK-AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA 1341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  672 EKEAALLQLREqlEGERKEAVAGLEKKHSAELEQlcssleakhqeviSSLQKKIEGAQQK-EEAQLQESLGWAEQRAHQK 750
Cdd:PTZ00121  1342 KKAAEAAKAEA--EAAADEAEAAEEKAEAAEKKK-------------EEAKKKADAAKKKaEEKKKADEAKKKAEEDKKK 1406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  751 VHQVTEYEQElssllRDKRQEVER--EHERKMDKMKEEhwqemadARERYEAEERKQRADLLGHLTGELERLRRAHEREL 828
Cdd:PTZ00121  1407 ADELKKAAAA-----KKKADEAKKkaEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  829 ESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQH 908
Cdd:PTZ00121  1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKA 1554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  909 LEEAKKEHTHLLETKqqlRRTIDDlrvRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPG 988
Cdd:PTZ00121  1555 EELKKAEEKKKAEEA---KKAEED---KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA 1628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  989 LHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAE-----GVAVRNAKEFLVRQTRSMRRRQTALKAAQQHW 1063
Cdd:PTZ00121  1629 EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEedkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEELK 1708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1064 RHELASAQEVDEDLPGTEV----LGNMRKNLNEETRHLDEMK-------SAMRKGHDLLKKKEEKLIQLESSLQEEVSDE 1132
Cdd:PTZ00121  1709 KKEAEEKKKAEELKKAEEEnkikAEEAKKEAEEDKKKAEEAKkdeeekkKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788

                          570
                   ....*....|....*..
gi 1907196499 1133 DTLKGSSIKKVTFDLSD 1149
Cdd:PTZ00121  1789 DEKRRMEVDKKIKDIFD 1805

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

616-1131

1.69e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 72.64 E-value: 1.69e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  616 EQQAALQRLREEAETLQkAERASLEQKsRRALEQLREQLEAEERSAQAALRAEKEAEKEAaLLQLREQLEGERKEAvagl 695
Cdd:COG4913    285 FAQRRLELLEAELEELR-AELARLEAE-LERLEARLDALREELDELEAQIRGNGGDRLEQ-LEREIERLERELEER---- 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  696 eKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQ------KEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDK- 768
Cdd:COG4913    358 -ERRRARLEALLAALGLPLPASAEEFAALRAEAAAllealeEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKs 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  769 ---------RQEVERE---HERKMD--------KMKEEHWQE-------------------MADARERYEAEERKQRADL 809
Cdd:COG4913    437 niparllalRDALAEAlglDEAELPfvgelievRPEEERWRGaiervlggfaltllvppehYAAALRWVNRLHLRGRLVY 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  810 LG-HLTGELERLRRAHEREL----------------ESMRQEQD-------QQLEDLRR-------------RHR----- 847
Cdd:COG4913    517 ERvRTGLPDPERPRLDPDSLagkldfkphpfrawleAELGRRFDyvcvdspEELRRHPRaitragqvkgngtRHEkddrr 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  848 ----------DHERKLQDLEVE---LSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAAlEREEATATHQHLEEAKK 914
Cdd:COG4913    597 rirsryvlgfDNRAKLAALEAElaeLEEELAEAEERLEALEAELDALQERREALQRLAEYSW-DEIDVASAEREIAELEA 675

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  915 EHTHLLETK---QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKemAAEMNASPHPEPGLhi 991
Cdd:COG4913    676 ELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE--AAEDLARLELRALL-- 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  992 EDLRKSLDtnknqevssslslskeeIDLSMESVRQFLSAEgvaVRNAKEFLVRQTRSMRRrqtALKAAQQHWRHELASAQ 1071
Cdd:COG4913    752 EERFAAAL-----------------GDAVERELRENLEER---IDALRARLNRAEEELER---AMRAFNREWPAETADLD 808

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907196499 1072 EVDEDLPGTEvlgNMRKNLNEE--TRHLDEMKSAmrkghdLLKKKEEKLIQLESSLQEEVSD 1131
Cdd:COG4913    809 ADLESLPEYL---ALLDRLEEDglPEYEERFKEL------LNENSIEFVADLLSKLRRAIRE 861

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

558-1127

4.98e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 4.98e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  558 QQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAetLQKAERA 637
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA--SLNNEIE 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  638 SLEQK---SRRALEQLREQLEAEERSAQAAlRAEKEAEKEAALLQLREQLEGERKEAVAGLE--KKHSAELEQLCSSLEA 712
Cdd:TIGR02168  404 RLEARlerLEDRRERLQQEIEELLKKLEEA-ELKELQAELEELEEELEELQEELERLEEALEelREELEEAEQALDAAER 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  713 KHQEVIS------SLQKKIEGAQQ--KEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVE----------- 773
Cdd:TIGR02168  483 ELAQLQArldsleRLQENLEGFSEgvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVvenlnaakkai 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  774 ---REHE--------------------RKMDKMKEEHWQEMADARERYEAEERKQRADLLGH------LTGELERLRRAH 824
Cdd:TIGR02168  563 aflKQNElgrvtflpldsikgteiqgnDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGvlvvddLDNALELAKKLR 642

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  825 EREL----------------------ESMRQEQDQQLEDLRRR-------HRDHERKLQDLEVELSSRTKDVKARLAQLN 875
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKieeleekIAELEKALAELRKELEELEEELEQLRKELE 722

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  876 VQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQ 955
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR 802

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  956 KHLSSLEAEVQRKQDVL--KEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDL--------SMESVR 1025
Cdd:TIGR02168  803 EALDELRAELTLLNEEAanLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeleseleALLNER 882

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1026 QFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQevdEDLPGTEV-LGNMRKNLNEETR-HLDEMKSA 1103
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE---LRLEGLEVrIDNLQERLSEEYSlTLEEAEAL 959

                          650       660
                   ....*....|....*....|....
gi 1907196499 1104 MRKGHDLLKKKEEKLIQLESSLQE 1127
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLENKIKE 983

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

604-933

1.54e-11

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 1.54e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  604 SRTEAFENQIRTEQQAALQRLREEAETLqKAERASLEQKSRRaLEQLREQLEAEERSAQAALRAEKEAekeaallqlREQ 683
Cdd:TIGR02169  659 SRAPRGGILFSRSEPAELQRLRERLEGL-KRELSSLQSELRR-IENRLDELSQELSDASRKIGEIEKE---------IEQ 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  684 LEGERKEAVAGLEkkhsaELEQLCSSLEAKHQEVISSLQKKIEGAQQKEE--AQLQESLGWAEQR-AHQKVHQVT----- 755
Cdd:TIGR02169  728 LEQEEEKLKERLE-----ELEEDLSSLEQEIENVKSELKELEARIEELEEdlHKLEEALNDLEARlSHSRIPEIQaelsk 802

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  756 --EYEQELSSLLRDKRQEVEREHERK--MDKMKEEHWQEMADARERyEAEERKQRADL---------------------- 809
Cdd:TIGR02169  803 leEEVSRIEARLREIEQKLNRLTLEKeyLEKEIQELQEQRIDLKEQ-IKSIEKEIENLngkkeeleeeleeleaalrdle 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  810 --LGHLTGELERLRrAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA---------RLAQLNVQE 878
Cdd:TIGR02169  882 srLGDLKKERDELE-AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelSLEDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  879 ENIRKEKQLLLDAQRQAALEREEATAThqhLEEAKKEHTHLLETKQQLRRTIDDL 933
Cdd:TIGR02169  961 QRVEEEIRALEPVNMLAIQEYEEVLKR---LDELKEKRAKLEEERKAILERIEEY 1012

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

599-1128

2.20e-11

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 68.84 E-value: 2.20e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERasleqksrraLEQLREQLEAEERSAQAALraekeaekeAALL 678
Cdd:TIGR00618  220 RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLK----------KQQLLKQLRARIEELRAQE---------AVLE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  679 QLREQLEGERKEAVAGLEKKHSAELEQ----LCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQv 754
Cdd:TIGR00618  281 ETQERINRARKAAPLAAHIKAVTQIEQqaqrIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRD- 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  755 tEYEQELSSLLRDKRQEVEREHERKMDKMKE-------------EHWQEMADARERYEAEERKQRADLLGHLTGELERLR 821
Cdd:TIGR00618  360 -AHEVATSIREISCQQHTLTQHIHTLQQQKTtltqklqslckelDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQR 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  822 RAHERELESMRQEQDQQLE-----DLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIR--KEKQLLLDAQRQ 894
Cdd:TIGR00618  439 YAELCAAAITCTAQCEKLEkihlqESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplCGSCIHPNPARQ 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  895 AALEREEATATHQHLEEAKKEHTHLLETkqqLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEV----QRKQD 970
Cdd:TIGR00618  519 DIDNPGPLTRRMQRGEQTYAQLETSEED---VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIpnlqNITVR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  971 VLKEMAAEMNASPHPEPGLHIEDLRKSLDTNkNQEVSSSLSLSKEEIDLSMESVRQFLSA-----EGVAVRNAKEFlvrQ 1045
Cdd:TIGR00618  596 LQDLTEKLSEAEDMLACEQHALLRKLQPEQD-LQDVRLHLQQCSQELALKLTALHALQLTltqerVREHALSIRVL---P 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1046 TRSMRRRQTALKAAQqhwrHELASAQEVDEDLPGT-EVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESS 1124
Cdd:TIGR00618  672 KELLASRQLALQKMQ----SEKEQLTYWKEMLAQCqTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKE 747


                   ....
gi 1907196499 1125 LQEE 1128
Cdd:TIGR00618  748 LMHQ 751

mukB

chromosome partition protein MukB;

610-961

2.50e-11

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 68.83 E-value: 2.50e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  610 ENQIRTEQQAaLQRLREEAETLqKAERASLEQksrrALEQLREQLEaeerSAQAALRAEKEAEK-EAALLQLREQLEgER 688
Cdd:PRK04863   299 RRQLAAEQYR-LVEMARELAEL-NEAESDLEQ----DYQAASDHLN----LVQTALRQQEKIERyQADLEELEERLE-EQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  689 KEAVAGL--------EKKHSAELEQLC--SSLeAKHQEVISSLQKKIEGAQQKEEAqLQESLGWAeQRAHQKVHQVTEYE 758
Cdd:PRK04863   368 NEVVEEAdeqqeeneARAEAAEEEVDElkSQL-ADYQQALDVQQTRAIQYQQAVQA-LERAKQLC-GLPDLTADNAEDWL 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  759 QELssllRDKRQEVE---REHERKMDkmkeehwqeMAD-ARERYEaeerkQRADLLGHLTGELERLR-----RAHERELE 829
Cdd:PRK04863   445 EEF----QAKEQEATeelLSLEQKLS---------VAQaAHSQFE-----QAYQLVRKIAGEVSRSEawdvaRELLRRLR 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  830 SMRQeQDQQLEDLRRRHRDHERKLQdLEVELSSRTKDVKARLAQ-----LNVQEENIRKEkQLLLDAQRQAALEREEATA 904
Cdd:PRK04863   507 EQRH-LAEQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKnlddeDELEQLQEELE-ARLESLSESVSEARERRMA 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  905 THQHLEEAKKEHTHL------------------------LETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSS 960
Cdd:PRK04863   584 LRQQLEQLQARIQRLaarapawlaaqdalarlreqsgeeFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIER 663


                   .
gi 1907196499  961 L 961
Cdd:PRK04863   664 L 664

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

475-979

2.68e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 2.68e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  475 QKLFSEAILKGMELEEDQRLLLEFQKEKPQQLEERLWREEEEKEEGEEEE------KEDEEEEGEEEEEEEEKEEEEEEE 548
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEeeleelEEELEEAEEELEEAEAELAEAEEA 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  549 EEEEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVcLRAQVQSRTEAFENQIRTEQQAALQRLREEA 628
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALE 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  629 ETLQKAERASLEQKS--RRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQL 706
Cdd:COG1196    446 EAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  707 CSSL---EAKHQEVI-----SSLQKKI----EGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLR-------- 766
Cdd:COG1196    526 VAVLigvEAAYEAALeaalaAALQNIVveddEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIgaavdlva 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  767 -DKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRR 845
Cdd:COG1196    606 sDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  846 HRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEkQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQ 925
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE-ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907196499  926 LRRTIDDLRVRRVELESqVDLL-----QAQSQRLQkHLSS----LEAEVQRKQDVLKEMAAEM 979
Cdd:COG1196    765 LERELERLEREIEALGP-VNLLaieeyEELEERYD-FLSEqredLEEARETLEEAIEEIDRET 825

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

625-969

1.90e-10

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 65.53 E-value: 1.90e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  625 REEAETLQKAERASLEQKSRRALEQL--REQLEAEERSAQAALRAEKEAEKEaallQLREQLEGERkeavaglekkhsaE 702
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAE----QERMAMERER-------------E 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  703 LEQLcsSLEAKHQEVISSLQKKIegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSsLLRDKRQEVEREHERKMDK 782
Cdd:pfam17380  350 LERI--RQEERKRELERIRQEEI--AMEISRMRELERLQMERQQKNERVRQELEAARKVK-ILEEERQRKIQQQKVEMEQ 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  783 MkeehwqemadareRYEAEERKQRadllghltgELERLRRAHERELESMRQE-QDQQLEDLRRRHRDHERKLQDLEVEls 861
Cdd:pfam17380  425 I-------------RAEQEEARQR---------EVRRLEEERAREMERVRLEeQERQQQVERLRQQEEERKRKKLELE-- 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  862 sRTKDVKARLAQLN--VQEENIRKEKQLLLDAQRQAAL------EREEATATHQHLEEAKKEHTHLLETKQqlRRTIDDL 933
Cdd:pfam17380  481 -KEKRDRKRAEEQRrkILEKELEERKQAMIEEERKRKLlekemeERQKAIYEEERRREAEEERRKQQEMEE--RRRIQEQ 557

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1907196499  934 RVRRVELESQVDLLQAQSQRLQKhlsSLEAEVQRKQ 969
Cdd:pfam17380  558 MRKATEERSRLEAMEREREMMRQ---IVESEKARAE 590

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

784-1079

2.06e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 2.06e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  784 KEEHWQEMADARERYEaEERKQRADLLGHLTGELERLRRAHeRELESMRQEQDQQLEDLRRRHRDHERKLQdlevELSSR 863
Cdd:TIGR02168  237 LREELEELQEELKEAE-EELEELTAELQELEEKLEELRLEV-SELEEEIEELQKELYALANEISRLEQQKQ----ILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  864 TKDVKARLAQLNVQEENIRKEKQLLLD--AQRQAALE--REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVE 939
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEelAELEEKLEelKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  940 LESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVlkemaaemnasphpepglhIEDLRKSLDTNKNQEVSSSLSLSKEEIDL 1019
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQE-------------------IEELLKKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1020 SMESVRqflsaegvAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDEDLPG 1079
Cdd:TIGR02168  452 LQEELE--------RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

PTZ00121

MAEBL; Provisional

603-1099

2.22e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.55 E-value: 2.22e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  603 QSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLE-QKSRRALEQLREQLEAEERSAQAalRAEKEAEKEAALLQLR 681
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKaDEAKKKAEEKKKADEAKKKAEEA--KKADEAKKKAEEAKKA 1459

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  682 EQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEVisslQKKIEGAQQKEEAQLQ-ESLGWAEQRahQKVHQVTEYEQE 760
Cdd:PTZ00121  1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA----KKKADEAKKAAEAKKKaDEAKKAEEA--KKADEAKKAEEA 1533

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  761 LSSLLRDKRQEVEREHE-RKMDKMKEEhwQEMADARERYEAEERKQRAdllghltgelerLRRAHE-RELESMRQEQDQQ 838
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADElKKAEELKKA--EEKKKAEEAKKAEEDKNMA------------LRKAEEaKKAEEARIEEVMK 1599

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  839 LEDLRRRHRDHERKLQD---LEVELSSRTKDVKARLAQL-NVQEENIRKEKQLLLDAQR---QAALEREEATATHQHLEE 911
Cdd:PTZ00121  1600 LYEEEKKMKAEEAKKAEeakIKAEELKKAEEEKKKVEQLkKKEAEEKKKAEELKKAEEEnkiKAAEEAKKAEEDKKKAEE 1679

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  912 AKKEHTHLLETKQQLRRTIDDLR----VRRVELESQV---DLLQAQSQRLQK--HLSSLEAEVQRKQDVLKEMAAEMNAS 982
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKkaeeLKKKEAEEKKkaeELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKI 1759

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  983 PH--PEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSA--EG-----VAVRNAKEFLVRQTRSMR-RR 1052
Cdd:PTZ00121  1760 AHlkKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANiiEGgkegnLVINDSKEMEDSAIKEVAdSK 1839

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1907196499 1053 QTALKAAQQHWRHELASAQEVDEDlpgtevlGNMRKNLNEETRHLDE 1099
Cdd:PTZ00121  1840 NMQLEEADAFEKHKFNKNNENGED-------GNKEADFNKEKDLKED 1879

PRK02224

DNA double-strand break repair Rad50 ATPase;

709-1127

2.37e-10

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 65.45 E-value: 2.37e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  709 SLEAKHQEVISSLQKKIEGaqqKEEAQLQESLGWAEQRAHQKVHQVTEYE--QELSSLLRDKRQEVEREHERKMDKMkEE 786
Cdd:PRK02224   180 RVLSDQRGSLDQLKAQIEE---KEEKDLHERLNGLESELAELDEEIERYEeqREQARETRDEADEVLEEHEERREEL-ET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  787 HWQEMADARERYEAEERKQRAdllghLTGELERLRRAHErELESMRQE--QDQQLEDL-RRRHRDHERKLQDLEVELSSR 863
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREE-----LAEEVRDLRERLE-ELEEERDDllAEAGLDDAdAEAVEARREELEDRDEELRDR 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  864 TKDVKARLAQLNVQEENIRKEKQLL----LDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVE 939
Cdd:PRK02224   330 LEECRVAAQAHNEEAESLREDADDLeeraEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGN 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  940 LESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDL 1019
Cdd:PRK02224   410 AEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1020 SMESVRQFLSAEGVAVRNAKEFlvrqTRSMRRRQTALKAAQQHwrhelasAQEVDEDlpgTEVLGNMRKNLNEETRHLDE 1099
Cdd:PRK02224   490 EVEEVEERLERAEDLVEAEDRI----ERLEERREDLEELIAER-------RETIEEK---RERAEELRERAAELEAEAEE 555

                          410       420
                   ....*....|....*....|....*...
gi 1907196499 1100 MKSAMRKGHDLLKKKEEKLIQLESSLQE 1127
Cdd:PRK02224   556 KREAAAEAEEEAEEAREEVAELNSKLAE 583

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

619-871

2.58e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 65.32 E-value: 2.58e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  619 AALQRLREEAETLQKAERASLE-QKSRRALEQLREQLE-----AEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAV 692
Cdd:COG4913    225 EAADALVEHFDDLERAHEALEDaREQIELLEPIRELAEryaaaRERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  693 AGLEkkhsAELEQLcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLlrdkrqEV 772
Cdd:COG4913    305 ARLE----AELERL-EARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL------GL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  773 EREHERKMDKMKEEHWQEMADARERYEAEERKQRAdllghltgELERLRRAHERELESMRQEqdqqLEDLRRRHRDHERK 852
Cdd:COG4913    374 PLPASAEEFAALRAEAAALLEALEEELEALEEALA--------EAEAALRDLRRELRELEAE----IASLERRKSNIPAR 441

                          250
                   ....*....|....*....
gi 1907196499  853 LQDLEVELSSRTKDVKARL 871
Cdd:COG4913    442 LLALRDALAEALGLDEAEL 460

PTZ00121

MAEBL; Provisional

560-934

3.04e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.16 E-value: 3.04e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  560 KEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASL 639
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  640 E-QKSRRALEQLREQLEAEERSAQAalRAEKEAEKEAALLQLREQLEGErkEAVAGLEKKHSAEL---EQLCSSLEAKH- 714
Cdd:PTZ00121  1491 KaEEAKKKADEAKKAAEAKKKADEA--KKAEEAKKADEAKKAEEAKKAD--EAKKAEEKKKADELkkaEELKKAEEKKKa 1566

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  715 ------QEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQElssllRDKRQEVEREHE--RKMDKMKEE 786
Cdd:PTZ00121  1567 eeakkaEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA-----KIKAEELKKAEEekKKVEQLKKK 1641

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  787 HWQEMADARE-RYEAEERKQRADLLGHLTGE----LERLRRAHERELESMRQ-----EQDQQLEDLRRRHRDHERKLQDL 856
Cdd:PTZ00121  1642 EAEEKKKAEElKKAEEENKIKAAEEAKKAEEdkkkAEEAKKAEEDEKKAAEAlkkeaEEAKKAEELKKKEAEEKKKAEEL 1721

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  857 EV----------ELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQhlEEAKKEHThllETKQQL 926
Cdd:PTZ00121  1722 KKaeeenkikaeEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE--EELDEEDE---KRRMEV 1796


                   ....*...
gi 1907196499  927 RRTIDDLR 934
Cdd:PTZ00121  1797 DKKIKDIF 1804

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

710-979

5.87e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 5.87e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  710 LEAKHQEVISSLQKKIEGAQQKEEAQ-LQESLGWAEQRAHqkVHQVTEYEQELSSLLRDkRQEVEREHErKMDKMKEEHW 788
Cdd:TIGR02169  189 LDLIIDEKRQQLERLRREREKAERYQaLLKEKREYEGYEL--LKEKEALERQKEAIERQ-LASLEEELE-KLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  789 QEMADARERYEAEERKQRAdllghLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSrtkdVK 868
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKD-----LGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK----LL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  869 ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEataTHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQ 948
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELED---LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1907196499  949 AQSQRLQKHLSSLEAEVQRKQDVLKEMAAEM 979
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEK 443

PRK02224

DNA double-strand break repair Rad50 ATPase;

607-970

8.71e-10

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 63.52 E-value: 8.71e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  607 EAFENQIRtEQQAALQRLREEAETLqkAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKeaallQLREQLEG 686
Cdd:PRK02224   275 EELAEEVR-DLRERLEELEEERDDL--LAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ-----AHNEEAES 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  687 ERKEAvAGLEKKhSAELEQLCSSLEA----------KHQEVISSLQKKIE---------GAQQKEEAQLQESLGWAEQRA 747
Cdd:PRK02224   347 LREDA-DDLEER-AEELREEAAELESeleeareaveDRREEIEELEEEIEelrerfgdaPVDLGNAEDFLEELREERDEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  748 HQKvhqVTEYEQELSSlLRDKRQEVER-----------------EH----ERKMDKmKEEHWQEMADARERYEA-EERKQ 805
Cdd:PRK02224   425 RER---EAELEATLRT-ARERVEEAEAlleagkcpecgqpvegsPHvetiEEDRER-VEELEAELEDLEEEVEEvEERLE 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  806 RADLLGHLTGELERLRRAHER------ELESMRQEQDQQLEDLRRRHRDHERKLQDLE---VELSSRTKDVKARLAQLNV 876
Cdd:PRK02224   500 RAEDLVEAEDRIERLEERREDleeliaERRETIEEKRERAEELRERAAELEAEAEEKReaaAEAEEEAEEAREEVAELNS 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  877 QEENIRKEKQLLLDAQRQAAlEREEATATHQHLEEAKKehtHLLETKQQLRRTIDDLRVRRVELESQVD-----LLQAQS 951
Cdd:PRK02224   580 KLAELKERIESLERIRTLLA-AIADAEDEIERLREKRE---ALAELNDERRERLAEKRERKRELEAEFDearieEAREDK 655

                          410
                   ....*....|....*....
gi 1907196499  952 QRLQKHLSSLEAEVQRKQD 970
Cdd:PRK02224   656 ERAEEYLEQVEEKLDELRE 674

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

756-974

1.90e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 62.06 E-value: 1.90e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  756 EYEQELSSLLRDKRQEVEREHERKMDKM--------KEEHWQEMADARERYEAEERKQRA-DLLGHLTGELERLRRAHER 826
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSERQQQEKFEKMeqerlrqeKEEKAREVERRRKLEEAEKARQAEmDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  827 ELESMRQEQ-DQQLEDLRRRHRDHE----RKLQDLEVELSSRTKDVKARLaqlnvqeENIRKEKQLLLDAQRQAALEREE 901
Cdd:pfam17380  349 ELERIRQEErKRELERIRQEEIAMEisrmRELERLQMERQQKNERVRQEL-------EAARKVKILEEERQRKIQQQKVE 421

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  902 ATATHQHLEEAKKEHTHLLETKqqlrRTIDDLRVRRVELE--SQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKE 974
Cdd:pfam17380  422 MEQIRAEQEEARQREVRRLEEE----RAREMERVRLEEQErqQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQ 492

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

616-978

3.29e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.32 E-value: 3.29e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  616 EQQAALQRLREEAETLQKAerasleQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGL 695
Cdd:COG4717     75 ELEEELKEAEEKEEEYAEL------QEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  696 E--KKHSAELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSL---LRDKRQ 770
Cdd:COG4717    149 EelEERLEELRELEEELEELEAE-LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAqeeLEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  771 EVEREHERKMDKMKEEHWQEMA-------------------------------------------DARERYEAEERKQRA 807
Cdd:COG4717    228 ELEQLENELEAAALEERLKEARlllliaaallallglggsllsliltiagvlflvlgllallfllLAREKASLGKEAEEL 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  808 DLLGHLTG----ELERLRRAH--------ERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA------ 869
Cdd:COG4717    308 QALPALEEleeeELEELLAALglppdlspEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVedeeel 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  870 RLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQA 949
Cdd:COG4717    388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467

                          410       420
                   ....*....|....*....|....*....
gi 1907196499  950 QSQrlqkhLSSLEAEVQRKQDVLKEMAAE 978
Cdd:COG4717    468 DGE-----LAELLQELEELKAELRELAEE 491

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

770-978

7.42e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.39 E-value: 7.42e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  770 QEVEREHERKMDKMKeehwQEMADARERYEAEERKQRAdllghLTGELERLRRAhERELESMRQEQDQQLEDLRRRHRDH 849
Cdd:COG4942     19 ADAAAEAEAELEQLQ----QEIAELEKELAALKKEEKA-----LLKQLAALERR-IAALARRIRALEQELAALEAELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  850 ERKLQDLEVELSSRTKDVKARLAQLnvQEENIRKEKQLLL------DAQRQAALEREEATATHQHLEEAKKEHTHLLETK 923
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRAL--YRLGRQPPLALLLspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  924 QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAE 978
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221

PTZ00121

MAEBL; Provisional

490-1128

8.06e-09

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.54 E-value: 8.06e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  490 EDQRLLLEFQKEKPQQLEERLWREEEEKEEGEEEEKEDEEEEGEEEEEEEEKEEEEEEEEEEEvcqlyQQKEKSLSLLKA 569
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKA-----EEARKAEDARKA 1142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  570 QlQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLRE--------EAETLQKAERASLEQ 641
Cdd:PTZ00121  1143 E-EARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDarkaeaarKAEEERKAEEARKAE 1221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  642 KSRRAlEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAE----LEQLCSSLEAKHQEV 717
Cdd:PTZ00121  1222 DAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADelkkAEEKKKADEAKKAEE 1300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  718 IsslqKKIEGAQQK-EEAQLQESLGWAEQRAHQKVHQVTEYEQElssllRDKRQEVER-EHERKMDKMKEEHWQEMADAR 795
Cdd:PTZ00121  1301 K----KKADEAKKKaEEAKKADEAKKKAEEAKKKADAAKKKAEE-----AKKAAEAAKaEAEAAADEAEAAEEKAEAAEK 1371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  796 ERyeaEERKQRADllgHLTGELERLRRAHerELESMRQEQDQQLEDLRRrhRDHERKLQDlevELSSRTKDVKaRLAQLN 875
Cdd:PTZ00121  1372 KK---EEAKKKAD---AAKKKAEEKKKAD--EAKKKAEEDKKKADELKK--AAAAKKKAD---EAKKKAEEKK-KADEAK 1437

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  876 VQEENIRKEKQLlldaqRQAALEREEATATHQHLEEAKKEHThlLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQ 955
Cdd:PTZ00121  1438 KKAEEAKKADEA-----KKKAEEAKKAEEAKKKAEEAKKADE--AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  956 KHLSSLEAEVQRKQDVLK--EMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRqflsAEgv 1033
Cdd:PTZ00121  1511 KADEAKKAEEAKKADEAKkaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK----AE-- 1584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1034 AVRNAKEFLVRQTRSMRRRQTALKAAQ-QHWRHELASAQEVDEDLPGTEVLGNMRKNLNEETRHLDEMKSAMR----KGH 1108
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEenkiKAA 1664

                          650       660
                   ....*....|....*....|
gi 1907196499 1109 DLLKKKEEKLIQLESSLQEE 1128
Cdd:PTZ00121  1665 EEAKKAEEDKKKAEEAKKAE 1684

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

763-956

8.22e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.17 E-value: 8.22e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  763 SLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdlLGHLTGELERLRRAHErELESMRQEQDQQLEDL 842
Cdd:COG4717     45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEE--YAELQEELEELEEELE-ELEAELEELREELEKL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  843 RR--RHRDHERKLQDLEVELSS---RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ-AALEREEATATHQHLEEAKKEH 916
Cdd:COG4717    122 EKllQLLPLYQELEALEAELAElpeRLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEEL 201

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1907196499  917 THLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQK 956
Cdd:COG4717    202 EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL 241

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

601-888

9.02e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 60.14 E-value: 9.02e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  601 QVQSRTEAFENQ-IRTEQQAALQRL--REEAETLQKAERASLEQKS-------RRALEQLRE--QLEAEERSAQAALRAE 668
Cdd:pfam17380  288 QQQEKFEKMEQErLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAaiyaeqeRMAMEREREleRIRQEERKRELERIRQ 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  669 KEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH 748
Cdd:pfam17380  368 EEIAMEISRMRELERLQMERQQKNERVRQELEAARKV--KILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  749 QKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERY----EAEERKQRADllghltgELERLRRAH 824
Cdd:pfam17380  446 REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKilekELEERKQAMI-------EEERKRKLL 518

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907196499  825 ERELEsmrQEQDQQLEDLRRRHRDHERKLQdLEVELSSRTKDVKARLAQLNVQEENIRKEKQLL 888
Cdd:pfam17380  519 EKEME---ERQKAIYEEERRREAEEERRKQ-QEMEERRRIQEQMRKATEERSRLEAMEREREMM 578

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

765-968

1.41e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.41e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  765 LRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEER-KQRADLLGHLTGELERLRR---AHERELESMRQEQDQQLE 840
Cdd:COG4942     25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiAALARRIRALEQELAALEAelaELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  841 DLRRRHRDHER--KLQDLEVELSS--------RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLE 910
Cdd:COG4942    105 ELAELLRALYRlgRQPPLALLLSPedfldavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907196499  911 EAKKEhthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 968
Cdd:COG4942    185 EERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

558-866

1.64e-08

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 1.64e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  558 QQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFENQI------RTEQQAALQRLREEAETL 631
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIeeleerLEEAEEELAEAEAEIEEL 787

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  632 Q-KAERASLE-QKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLcss 709
Cdd:TIGR02168  788 EaQIEQLKEElKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL--- 864

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  710 leakhQEVISSLQKKIEGAQqKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMD----KMKE 785
Cdd:TIGR02168  865 -----EELIEELESELEALL-NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRleglEVRI 938

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  786 EHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESM-----------------RQEQDQQLEDLRRRHRD 848
Cdd:TIGR02168  939 DNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieeyeelkerYDFLTAQKEDLTEAKET 1018

                          330
                   ....*....|....*...
gi 1907196499  849 HERKLQDLEVELSSRTKD 866
Cdd:TIGR02168 1019 LEEAIEEIDREARERFKD 1036

PRK12704

phosphodiesterase; Provisional

777-918

1.69e-08

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 58.64 E-value: 1.69e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  777 ERKMDKMKEEHWQEMADAREryEAEERKQRADLlgHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 856
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKK--EAEAIKKEALL--EAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499  857 ---EVELSSRTKDVKARLAQLNVQEENI-RKEKQLLLDAQRQAALEREEATAthQHLEEAKKEHTH 918
Cdd:PRK12704   106 ekrEEELEKKEKELEQKQQELEKKEEELeELIEEQLQELERISGLTAEEAKE--ILLEKVEEEARH 169

PTZ00121

MAEBL; Provisional

543-1142

2.12e-08

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.38 E-value: 2.12e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  543 EEEEEeeeeevcqlyqqkekslsllkaQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFEnqiRTEQQAALQ 622
Cdd:PTZ00121  1239 AEEAK----------------------KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKAD 1293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  623 RLReEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREqlEGERKEAVAGLEKKHSAE 702
Cdd:PTZ00121  1294 EAK-KAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA--EAAADEAEAAEEKAEAAE 1370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  703 LEQlcssleakhqeviSSLQKKIEGAQQK-EEAQLQESLGWAEQRAHQKVHQVTEYEQElssllRDKRQEVER--EHERK 779
Cdd:PTZ00121  1371 KKK-------------EEAKKKADAAKKKaEEKKKADEAKKKAEEDKKKADELKKAAAA-----KKKADEAKKkaEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  780 MDKMKEEhwqemadARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVE 859
Cdd:PTZ00121  1433 ADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKA 1505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  860 LSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKqqlRRTIDDlrvRRVE 939
Cdd:PTZ00121  1506 AEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEA---KKAEED---KNMA 1579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  940 LESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEmaaemnaspHPEPGLHIEDLRKSLDTNKNQEvssSLSLSKEEIDL 1019
Cdd:PTZ00121  1580 LRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK---------AEEAKIKAEELKKAEEEKKKVE---QLKKKEAEEKK 1647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1020 SMESVRQflSAEGVAVRnaKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDEDLPGTEvlgNMRKNLNEETRHLDE 1099
Cdd:PTZ00121  1648 KAEELKK--AEEENKIK--AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE---ELKKKEAEEKKKAEE 1720

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907196499 1100 MKsamrkghdllKKKEEKLIQLESSLQEEvsDEDTLKGSSIKK 1142
Cdd:PTZ00121  1721 LK----------KAEEENKIKAEEAKKEA--EEDKKKAEEAKK 1751

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

555-916

2.47e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 2.47e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  555 QLYQQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLvclrAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKA 634
Cdd:COG4717    132 QELEALEAELAELPERLEELEERLEELRELEEELEELEAEL----AELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  635 ERASLE--QKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSL-- 710
Cdd:COG4717    208 LAELEEelEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLla 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  711 -----EAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQR---AHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDK 782
Cdd:COG4717    288 llfllLAREKASLGKEAEELQALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEELQLEE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  783 MKEE-----------------HWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRR 845
Cdd:COG4717    368 LEQEiaallaeagvedeeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEE 447

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  846 HRDHERKLQDLEVELSSRTKDvkARLAQLnvqeeniRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEH 916
Cdd:COG4717    448 LEELREELAELEAELEQLEED--GELAEL-------LQELEELKAELRELAEEWAALKLALELLEEAREEY 509

PRK03918

DNA double-strand break repair ATPase Rad50;

715-1128

2.64e-08

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 2.64e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  715 QEVISSLQKKIEGAQQ--KEEAQLQESLGWAEQRAHQKVHQVteyeQELSSLLRDKRQEVE--REHERKMDKMKEEHwqe 790
Cdd:PRK03918   168 GEVIKEIKRRIERLEKfiKRTENIEELIKEKEKELEEVLREI----NEISSELPELREELEklEKEVKELEELKEEI--- 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  791 madareryeAEERKQRADLLGHLTGELERLR---------RAHERELESMRQEQDQ---------QLEDLRRRHRDHERK 852
Cdd:PRK03918   241 ---------EELEKELESLEGSKRKLEEKIReleerieelKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDELRE 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  853 LQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ------AALEREEATATHQHLEEAKKEHTHLleTKQQL 926
Cdd:PRK03918   312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRleeleeRHELYEEAKAKKEELERLKKRLTGL--TPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  927 RRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR-----------KQDVLKEMAAEMNASPHPEpglhIEDLR 995
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcGRELTEEHRKELLEEYTAE----LKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  996 KSLDTNKNQEVSSSLSLSKEEIDLSMEsvRQFLSAEGVA--VRNAKEFLvrqtrsmrrRQTALKAAQQHWRhelaSAQEV 1073
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKE--SELIKLKELAeqLKELEEKL---------KKYNLEELEKKAE----EYEKL 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499 1074 DEDLPGtevLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1128
Cdd:PRK03918   531 KEKLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

624-1150

3.64e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 58.26 E-value: 3.64e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  624 LREEAETLQKAERASLEQKSR-RALEQ----LREQLEAEERSAQAALRAEKEAEKEaaLLQLREQLEGERKEAVAGLE-- 696
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRlRQLEDernsLQEQLEEEEEAKRNVERQLSTLQAQ--LSDMKKKLEEDAGTLEALEEgk 547

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  697 KKHSAELEQLCSSLEAKHQEViSSLQKKIEGAQQKEEAQL-----QESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQE 771
Cdd:pfam01576  548 KRLQRELEALTQQLEEKAAAY-DKLEKTKNRLQQELDDLLvdldhQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDR 626

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  772 VE---REHERKMDKMKEEhWQEMADARERYEAEERKQRADL---------LGHLTGELERLRRAHERELESMRqEQDQQL 839
Cdd:pfam01576  627 AEaeaREKETRALSLARA-LEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKRALEQQVEEMK-TQLEEL 704

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  840 EDLRRRHRD---------------HERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA-- 902
Cdd:pfam01576  705 EDELQATEDaklrlevnmqalkaqFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELea 784

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  903 --TATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVEL-------ESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK 973
Cdd:pfam01576  785 qiDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEIlaqskesEKKLKNLEAELLQLQEDLAASERARRQAQQERD 864

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  974 EMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEID-------LSMESVRQFLSAEGVA---VRNAKEFLV 1043
Cdd:pfam01576  865 ELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNdrlrkstLQVEQLTTELAAERSTsqkSESARQQLE 944

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1044 RQTRSMRRR--------QTALKAAQQHWRHELASA-----QEVDEDLPGTEVLGNMRKNLNE-------ETRHLDEMKSA 1103
Cdd:pfam01576  945 RQNKELKAKlqemegtvKSKFKSSIAALEAKIAQLeeqleQESRERQAANKLVRRTEKKLKEvllqvedERRHADQYKDQ 1024

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1907196499 1104 MRKGHDLLKkkeekliQLESSLqEEVSDEDTLKGSSIKKVTFDLSDM 1150
Cdd:pfam01576 1025 AEKGNSRMK-------QLKRQL-EEAEEEASRANAARRKLQRELDDA 1063

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

598-1006

4.89e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.93 E-value: 4.89e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  598 LRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQ-KAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAA 676
Cdd:pfam12128  409 QLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKsRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVE 488

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  677 LLQLRE-QLEGERKEAVAGLEKKHSAeLEQLCSSLEAKHQEVISSLQKKIEgAQQKEEAQLQESLGW---AEQRAHQKVH 752
Cdd:pfam12128  489 RLQSELrQARKRRDQASEALRQASRR-LEERQSALDELELQLFPQAGTLLH-FLRKEAPDWEQSIGKvisPELLHRTDLD 566

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  753 QVTEYEQELSSL------LRDKRQEV------EREHERKMDKMKEehwqEMADARERYEAEERKqradlLGHLTGELERL 820
Cdd:pfam12128  567 PEVWDGSVGGELnlygvkLDLKRIDVpewaasEEELRERLDKAEE----ALQSAREKQAAAEEQ-----LVQANGELEKA 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  821 RRAHERELES--------------MRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQ 886
Cdd:pfam12128  638 SREETFARTAlknarldlrrlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQ 717

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  887 LL-----------LDAQRQAALEREEATATHQ-------HLEEAKK--EHTHLLETKQQLR---RTIDDLRVRRVELESQ 943
Cdd:pfam12128  718 AYwqvvegaldaqLALLKAAIAARRSGAKAELkaletwyKRDLASLgvDPDVIAKLKREIRtleRKIERIAVRRQEVLRY 797

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  944 VDLLQA----QSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNasphpepgLHIEDLRKSLDTNKNQEV 1006
Cdd:pfam12128  798 FDWYQEtwlqRRPRLATQLSNIERAISELQQQLARLIADTK--------LRRAKLEMERKASEKQQV 856

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

593-875

9.27e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 9.27e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  593 RRLVCLRAQVQSRTEAFE--NQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraeke 670
Cdd:COG4913    610 AKLAALEAELAELEEELAeaEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDAS------ 683

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  671 aekEAALLQLREQLEgERKEAVAGLEKKHsAELEQLCSSLEAKH---QEVISSLQKKIEGAQQKEEAQLQESLgwaEQRA 747
Cdd:COG4913    684 ---SDDLAALEEQLE-ELEAELEELEEEL-DELKGEIGRLEKELeqaEEELDELQDRLEAAEDLARLELRALL---EERF 755

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  748 HQkvHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEehwqEMADARERYEAEERKQRADL--LGHLTGELERLR---- 821
Cdd:COG4913    756 AA--ALGDAVERELRENLEERIDALRARLNRAEEELER----AMRAFNREWPAETADLDADLesLPEYLALLDRLEedgl 829

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  822 -RAHERELESMRQEQDQQLEDLRRRHRDHERklqdlevelssrtkDVKARLAQLN 875
Cdd:COG4913    830 pEYEERFKELLNENSIEFVADLLSKLRRAIR--------------EIKERIDPLN 870

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

605-893

9.91e-08

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 9.91e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  605 RTEAFENQIRT--EQQAALQRLREEAETLQKAERASLEQksrraLEQLREQLEAEERSAQAALRAEKEAEKEaalLQLRE 682
Cdd:TIGR02168  233 RLEELREELEElqEELKEAEEELEELTAELQELEEKLEE-----LRLEVSELEEEIEELQKELYALANEISR---LEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  683 QLEGERKEAVAGLEKKHSAELEQLCSSLEAKhQEVISSLQKKIEGAQQK--EEAQLQESLGWAEQRAHQKVHQVTEYEQE 760
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDEL-AEELAELEEKLEELKEEleSLEAELEELEAELEELESRLEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  761 LSSLLRDKRQEVEREHERKmdKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQD---Q 837
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEI--ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELErleE 461

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  838 QLEDLRRRHRDHERKLQDLEVELSSrtkdVKARLAQLNVQEENIRKE----KQLLLDAQR 893
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQ----LQARLDSLERLQENLEGFsegvKALLKNQSG 517

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

599-767

2.14e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.41 E-value: 2.14e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIRT------EQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAE 672
Cdd:COG3206    170 REEARKALEFLEEQLPElrkeleEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  673 KEAA--------------LLQLREQLEGERKEAVAGLEKKHS------AELEQLCSSLEAKHQEVISSLQKKIEGAQQkE 732
Cdd:COG3206    250 GSGPdalpellqspviqqLRAQLAELEAELAELSARYTPNHPdvialrAQIAALRAQLQQEAQRILASLEAELEALQA-R 328

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1907196499  733 EAQLQESLgwaeQRAHQKVHQVTEYEQELSSLLRD 767
Cdd:COG3206    329 EASLQAQL----AQLEARLAELPELEAELRRLERE 359

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

629-933

2.68e-07

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 55.61 E-value: 2.68e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  629 ETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraekeaekEAALLQLREQLEGERKEAVAGLEKKHSAELEQlcS 708
Cdd:pfam12128  588 KRIDVPEWAASEEELRERLDKAEEALQSAREKQAAA---------EEQLVQANGELEKASREETFARTALKNARLDL--R 656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  709 SLEAKHQEVISSLQKKIEGAQQKEEAQLQESLgwAEQRAHQKVHQVTEYEQ-----ELSSLLRDKRQEVEREHERKMDKM 783
Cdd:pfam12128  657 RLFDEKQSEKDKKNKALAERKDSANERLNSLE--AQLKQLDKKHQAWLEEQkeqkrEARTEKQAYWQVVEGALDAQLALL 734

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  784 KEE--HWQEMADARERYEAEERKQRADLLG--------------HLTGELERL--RRAHERELESMRQEQ-DQQLEDLRR 844
Cdd:pfam12128  735 KAAiaARRSGAKAELKALETWYKRDLASLGvdpdviaklkreirTLERKIERIavRRQEVLRYFDWYQETwLQRRPRLAT 814

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  845 RHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQR--QAALEREEATATHQHLEEAKKEHTHLLET 922
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRglRCEMSKLATLKEDANSEQAQGSIGERLAQ 894

                          330
                   ....*....|.
gi 1907196499  923 KQQLRRTIDDL 933
Cdd:pfam12128  895 LEDLKLKRDYL 905

PRK02224

DNA double-strand break repair Rad50 ATPase;

547-979

2.82e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.43 E-value: 2.82e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  547 EEEEEEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLR---AQVQSRTEAFENQIRTEQQAAL-- 621
Cdd:PRK02224   275 EELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRdrlEECRVAAQAHNEEAESLREDADdl 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  622 ----QRLREEAETLQKAERASLEQ--KSRRALEQLREQLE-AEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAG 694
Cdd:PRK02224   355 eeraEELREEAAELESELEEAREAveDRREEIEELEEEIEeLRERFGDAPVDLGNAEDFLEELREERDELREREAELEAT 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  695 LE--KKHSAELEQL-----CSSL-----EAKHQEVISSLQKKIEG-----AQQKEE-AQLQESLGWAEQ--RAHQKVHQV 754
Cdd:PRK02224   435 LRtaRERVEEAEALleagkCPECgqpveGSPHVETIEEDRERVEEleaelEDLEEEvEEVEERLERAEDlvEAEDRIERL 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  755 TEYEQELSSLLRDKRQEVEREHER--KMDKMKEEHWQEMADARE-----RYEAEERKQRADLL----GHLTGELERLRRA 823
Cdd:PRK02224   515 EERREDLEELIAERRETIEEKRERaeELRERAAELEAEAEEKREaaaeaEEEAEEAREEVAELnsklAELKERIESLERI 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  824 heRELESMRQEQDQQLEDLRRRHRDherkLQDLEVELSSRTKDVKARLAQL--NVQEENIRKEKQllldaqrqaalEREE 901
Cdd:PRK02224   595 --RTLLAAIADAEDEIERLREKREA----LAELNDERRERLAEKRERKRELeaEFDEARIEEARE-----------DKER 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  902 ATathQHLEEAKKEHTHLLETKQQLRRTI----------DDLRVRRVELESQVDLLQA---QSQRLQKHLSSLEAEV-QR 967
Cdd:PRK02224   658 AE---EYLEQVEEKLDELREERDDLQAEIgaveneleelEELRERREALENRVEALEAlydEAEELESMYGDLRAELrQR 734

                          490
                   ....*....|..
gi 1907196499  968 KQDVLKEMAAEM 979
Cdd:PRK02224   735 NVETLERMLNET 746

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

592-963

3.35e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 55.34 E-value: 3.35e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  592 SRRLVCLRAQVQSRTEAFENQ-IRTEQQAALQRLREEAETLQKAERAsLEQKSRRALEQLREqleaeersAQAALRAEKE 670
Cdd:COG3096    278 NERRELSERALELRRELFGARrQLAEEQYRLVEMARELEELSARESD-LEQDYQAASDHLNL--------VQTALRQQEK 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  671 -AEKEAALLQLREQLEgERKEAVAGL--------EKKHSAELE--QLCSSLeAKHQEVISSLQKKIEGAQQ----KEEAQ 735
Cdd:COG3096    349 iERYQEDLEELTERLE-EQEEVVEEAaeqlaeaeARLEAAEEEvdSLKSQL-ADYQQALDVQQTRAIQYQQavqaLEKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  736 LQ---ESLGWAEQRAHQKVHQvtEYEQELSSLLRDKRQEVE------REHERKMdkmkeEHWQEMADARERYEAEERKQ- 805
Cdd:COG3096    427 ALcglPDLTPENAEDYLAAFR--AKEQQATEEVLELEQKLSvadaarRQFEKAY-----ELVCKIAGEVERSQAWQTARe 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  806 ---RADLLGHLTGELERLRRAH---ERELESmRQEQDQQLEDLRRRH---RDHERKLQDLEVELSSRTKDVKARLAqlNV 876
Cdd:COG3096    500 llrRYRSQQALAQRLQQLRAQLaelEQRLRQ-QQNAERLLEEFCQRIgqqLDAAEELEELLAELEAQLEELEEQAA--EA 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  877 QEENIRKEKQLLLDAQRQAALEREE-----ATATHQHLEEAKKEHthlLETKQQLRRTIDDLRVRRVELESQVDLLQAQS 951
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAARApawlaAQDALERLREQSGEA---LADSQEVTAAMQQLLEREREATVERDELAARK 653

                          410
                   ....*....|..
gi 1907196499  952 QRLQKHLSSLEA 963
Cdd:COG3096    654 QALESQIERLSQ 665

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

805-981

3.37e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 53.00 E-value: 3.37e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  805 QRADLLGHLTGELERLRRAHERELESMRQEqdqqLEDLRRRHRDHERKLQDLEVELssrtKDVKARLAQLNVQEENIRKE 884
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEAR----LEAAKTELEDLEKEIKRLELEI----EEVEARIKKYEEQLGNVRNN 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  885 KQLlldaqrqAALEREEATATHQhLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAqsqRLQKHLSSLEAE 964
Cdd:COG1579     89 KEY-------EALQKEIESLKRR-ISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAE 157

                          170
                   ....*....|....*..
gi 1907196499  965 VQRKQDVLKEMAAEMNA 981
Cdd:COG1579    158 LEELEAEREELAAKIPP 174

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

641-984

5.48e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 53.98 E-value: 5.48e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  641 QKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAAL---LQLREQLEGERKEA------VAGLEKKHSAELEQLCS--- 708
Cdd:pfam05557   17 EKKQMELEHKRARIELEKKASALKRQLDRESDRNQELqkrIRLLEKREAEAEEAlreqaeLNRLKKKYLEALNKKLNeke 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  709 SLEAKHQEVISSLQKKIEGAQ---QKEEAQLQESLGWAE--QRAHQKVHQ-VTEYEQELSSLlrDKRQEVEREHERKMDK 782
Cdd:pfam05557   97 SQLADAREVISCLKNELSELRrqiQRAELELQSTNSELEelQERLDLLKAkASEAEQLRQNL--EKQQSSLAEAEQRIKE 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  783 MKEEHWQEMADARERYEAEERKQRadlLGHLTGELERLRR--AHERELESMRQEQDQQLEDLRR---RHRDHERKLQDLE 857
Cdd:pfam05557  175 LEFEIQSQEQDSEIVKNSKSELAR---IPELEKELERLREhnKHLNENIENKLLLKEEVEDLKRkleREEKYREEAATLE 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  858 VELSSRTKDVKA--RLAQ-----LNVQEENIRKEKQLLldaQRQAALEREEATATHQ--HLEEAKKEhthLLETKQQLRR 928
Cdd:pfam05557  252 LEKEKLEQELQSwvKLAQdtglnLRSPEDLSRRIEQLQ---QREIVLKEENSSLTSSarQLEKARRE---LEQELAQYLK 325

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499  929 TIDDLRVRRVELESQVDllqaqsqRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPH 984
Cdd:pfam05557  326 KIEDLNKKLKRHKALVR-------RLQRRVLLLTKERDGYRAILESYDKELTMSNY 374

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

437-891

5.62e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 5.62e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  437 EAQGLDQEEQDDSKSSIAEPQSKHTQGSERQTAEPAAPQKLFSEAILKGMELEEDQRLLLEFQKEKPQQLEERLWREEEE 516
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  517 KEEGEEEEKEDEEEEGEE------EEEEEEKEEEEEEEEEEEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEETKIREE 590
Cdd:COG1196    437 EEEEEEALEEAAEEEAELeeeeeaLLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  591 ESRRLVCLR-AQVQSRTEAFENQIRTEQQAALQ-RLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAE 668
Cdd:COG1196    517 AGLRGLAGAvAVLIGVEAAYEAALEAALAAALQnIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  669 KEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEvisslQKKIEGAQQKEEAQLQESLGWAEQRAH 748
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG-----RLREVTLEGEGGSAGGSLTGGSRRELL 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  749 QKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHEREL 828
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  829 ESMRQEQDQQLEDLRRRHRDHERKLQDL-------EVELssrtKDVKARLAQLNVQEENIRKEKQLLLDA 891
Cdd:COG1196    752 ALEELPEPPDLEELERELERLEREIEALgpvnllaIEEY----EELEERYDFLSEQREDLEEARETLEEA 817

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

801-1060

6.73e-07

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 53.37 E-value: 6.73e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  801 EERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEEN 880
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  881 IRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSS 960
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  961 LEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKE 1040
Cdd:COG4372    169 LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248

                          250       260
                   ....*....|....*....|
gi 1907196499 1041 FLVRQTRSMRRRQTALKAAQ 1060
Cdd:COG4372    249 EELLEEVILKEIEELELAIL 268

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

706-1124

7.78e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.62 E-value: 7.78e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  706 LCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAEQRaHQKVHQVTEYEQELSSLLRDKRQEVE--REHERKMDKM 783
Cdd:COG4717     47 LLERLEKEADE-LFKPQGRKPELNLKELKELEEELKEAEEK-EEEYAELQEELEELEEELEELEAELEelREELEKLEKL 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  784 KE--EHWQEMADARERYEA------------EERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDH 849
Cdd:COG4717    125 LQllPLYQELEALEAELAElperleeleerlEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  850 ERKLQDLEVELssrtKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALERE--------EATATHQHLEEAKKEHTHLLE 921
Cdd:COG4717    205 QQRLAELEEEL----EEAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallALLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  922 TKQQLRrTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEaevqrkqdvLKEMAAEMNASPHPEPGlHIEDLRKSLDTN 1001
Cdd:COG4717    281 LVLGLL-ALLFLLLAREKASLGKEAEELQALPALEELEEEE---------LEELLAALGLPPDLSPE-ELLELLDRIEEL 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1002 KNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAvrNAKEFLVRQTRSmrRRQTALKAAQQHWRHELASAQEVDEDLPGTE 1081
Cdd:COG4717    350 QELLREAEELEEELQLEELEQEIAALLAEAGVE--DEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEAL 425

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1907196499 1082 VLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESS 1124
Cdd:COG4717    426 DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

691-904

1.10e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 1.10e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  691 AVAGLEKKHSAELEQLcssleakhQEVISSLQKKIEgAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSL------ 764
Cdd:COG4942     17 AQADAAAEAEAELEQL--------QQEIAELEKELA-ALKKEEKALLKQLAALERRIAALARRIRALEQELAALeaelae 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  765 LRDKRQEVEREHERKMDKMKE--------------------EHWQEMADARERYEA--EERKQRADLLGHLTGELERLRR 822
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAEllralyrlgrqpplalllspEDFLDAVRRLQYLKYlaPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  823 aherELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA 902
Cdd:COG4942    168 ----ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ..
gi 1907196499  903 TA 904
Cdd:COG4942    244 PA 245

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

718-965

1.12e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 1.12e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  718 ISSLQKKIEGAQQKEEA--QLQEslgwAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHwQEMADAR 795
Cdd:COG4913    237 LERAHEALEDAREQIELlePIRE----LAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL-ARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  796 ERYEAEERKQRADLLghltgELERLRRAHE-RELESMRQEQDQ---QLEDLRRRHRDHERKLQDLEVELSSRTKDVKARL 871
Cdd:COG4913    312 ERLEARLDALREELD-----ELEAQIRGNGgDRLEQLEREIERlerELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  872 AQLnvqeenirkeKQLLLDAQRQAALEREEATATHQHLEEAKKEHthlletkQQLRRTIDDLRVRRVELESQVDLLQAqs 951
Cdd:COG4913    387 AEA----------AALLEALEEELEALEEALAEAEAALRDLRREL-------RELEAEIASLERRKSNIPARLLALRD-- 447

                          250
                   ....*....|....
gi 1907196499  952 qRLQKHLSSLEAEV 965
Cdd:COG4913    448 -ALAEALGLDEAEL 460

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

558-961

2.86e-06

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.15 E-value: 2.86e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  558 QQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVclrAQVQSRTEAFENQIRTEQQAALQRLREEAetlqkAERA 637
Cdd:pfam12128  621 AAAEEQLVQANGELEKASREETFARTALKNARLDLRRLF---DEKQSEKDKKNKALAERKDSANERLNSLE-----AQLK 692

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  638 SLEQKSRRALEQLREQLEAEERSAQAALRAekeaekeaallqlreqLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEV 717
Cdd:pfam12128  693 QLDKKHQAWLEEQKEQKREARTEKQAYWQV----------------VEGALDAQLALLKAAIAARRSGAKAELKALETWY 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  718 ISSLQKK-IEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYE---QELSSLLRDKRQEVEREHERKMDKMKEEHWQEMAD 793
Cdd:pfam12128  757 KRDLASLgVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFdwyQETWLQRRPRLATQLSNIERAISELQQQLARLIAD 836

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  794 ARERYEAEER------KQRADLLGHLTG---ELERLRRAHE----RELESMRQEQDQQLEDLRRRHR----DHERKLQDL 856
Cdd:pfam12128  837 TKLRRAKLEMerkaseKQQVRLSENLRGlrcEMSKLATLKEdansEQAQGSIGERLAQLEDLKLKRDylseSVKKYVEHF 916

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  857 EVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREE-ATATHQHLEEAKKEHTHLL-ETKQQLRRTIDDLR 934
Cdd:pfam12128  917 KNVIADHSGSGLAETWESLREEDHYQNDKGIRLLDYRKLVPYLEQwFDVRVPQSIMVLREQVSILgVDLTEFYDVLADFD 996

                          410       420
                   ....*....|....*....|....*..
gi 1907196499  935 VRrvelesqvdlLQAQSQRLQKHLSSL 961
Cdd:pfam12128  997 RR----------IASFSRELQREVGEE 1013

PTZ00121

MAEBL; Provisional

521-1149

2.89e-06

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.07 E-value: 2.89e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  521 EEEEKEDEEEEGEEEEEEEEKEEEEEEEEEEEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRA 600
Cdd:PTZ00121  1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE 1360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  601 QVQSRTEAFENQIRTEQQAAlQRLREEAETLQKAERASLE-QKSRRALEQLREQLEAEERSAQAALRAEKEAEKeaallq 679
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKKKA-DAAKKKAEEKKKADEAKKKaEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA------ 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  680 lrEQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEvisslQKKIEGAQQK-EEAQLQESLGWAEQRAHQKVHQVTEYE 758
Cdd:PTZ00121  1434 --DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE-----AKKADEAKKKaEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  759 QElssllRDKRQEVER-EHERKMDKMKEEhwQEMADARERYEAEERKQRADLlghltGELERLRRAHE-RELESMRQEQD 836
Cdd:PTZ00121  1507 EA-----KKKADEAKKaEEAKKADEAKKA--EEAKKADEAKKAEEKKKADEL-----KKAEELKKAEEkKKAEEAKKAEE 1574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  837 QQLEDLRRRH--RDHERKLQDLEVELSSRTKDVKARLA----QLNVQEENIRKEKQLLLDAQRQAALEREEAtathQHLE 910
Cdd:PTZ00121  1575 DKNMALRKAEeaKKAEEARIEEVMKLYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEK----KKAE 1650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  911 EAKKEHTHLLETKQQLRRTIDDLRVRRVEL-ESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGL 989
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAkKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  990 HIEDLRKSLDTNKNQevsSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQ--TRSMRRRQTALKAAQQHWRHEL 1067
Cdd:PTZ00121  1731 KAEEAKKEAEEDKKK---AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEelDEEDEKRRMEVDKKIKDIFDNF 1807

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1068 ASAQEVDEDlpGTEVLGNMRKNLNEETRHLDEMKSAMRkghdllkkKEEKLIQLESSLQEEVSDEDTLKGSSIKKVTFDL 1147
Cdd:PTZ00121  1808 ANIIEGGKE--GNLVINDSKEMEDSAIKEVADSKNMQL--------EEADAFEKHKFNKNNENGEDGNKEADFNKEKDLK 1877


                   ..
gi 1907196499 1148 SD 1149
Cdd:PTZ00121  1878 ED 1879

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

891-1118

2.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.93e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  891 AQRQAALE--REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 968
Cdd:COG4942     23 AEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  969 QDVLKEMAAE---MNASPHPEPGLHIEDlrkSLDTNKNQEVssslslskeeidlsMESVRQFLSAEGVAVRNAKEFLVRQ 1045
Cdd:COG4942    103 KEELAELLRAlyrLGRQPPLALLLSPED---FLDAVRRLQY--------------LKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196499 1046 TRS---MRRRQTALKAAQQHWRHELASAQEVDEDLpgtevLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKL 1118
Cdd:COG4942    166 RAEleaERAELEALLAELEEERAALEALKAERQKL-----LARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

637-905

3.17e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 3.17e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  637 ASLEQKSRRALEQLREQLEAEERSAQAALraekeaekeaallqlrEQLEGERKEAVAGLEK--KHSAELEQLCSSLEAKh 714
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKEL----------------AALKKEEKALLKQLAAleRRIAALARRIRALEQE- 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  715 qevISSLQKKIEGAqQKEEAQLQESLgwAEQRAhqkvhqvtEYEQELSSLLRDKRQeverehERKMDKMKEEHWQEMADA 794
Cdd:COG4942     78 ---LAALEAELAEL-EKEIAELRAEL--EAQKE--------ELAELLRALYRLGRQ------PPLALLLSPEDFLDAVRR 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  795 RERYEA--EERKQRADLLGHLTGELERLRRAHERE---LESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRtkdvKA 869
Cdd:COG4942    138 LQYLKYlaPARREQAEELRADLAELAALRAELEAEraeLEALLAELEEERAALEALKAERQKLLARLEKELAEL----AA 213

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1907196499  870 RLAQLNVQEENIRKekqlLLDAQRQAALEREEATAT 905
Cdd:COG4942    214 ELAELQQEAEELEA----LIARLEAEAAAAAERTPA 245

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

833-981

3.92e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.54 E-value: 3.92e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  833 QEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLldAQRQAALEREEatathQHLEEA 912
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI--EEVEARIKKYE-----EQLGNV 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  913 K--KEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNA 981
Cdd:COG1579     86 RnnKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

604-1122

4.33e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.66 E-value: 4.33e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  604 SRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEqlREQLEAEERSAQAALRAEKEAekeaalLQLREQ 683
Cdd:pfam15921  320 SDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTE--RDQFSQESGNLDDQLQKLLAD------LHKREK 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  684 ---LEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEViSSLQKKIEGAQQKEEAQLQESLGwAEQRAHQKVHQVTEYEQE 760
Cdd:pfam15921  392 elsLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEV-QRLEALLKAMKSECQGQMERQMA-AIQGKNESLEKVSSLTAQ 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  761 LSSLLRDKRQEVEREHERKMDKMKEEH--------WQEMADARERYEAE--ERKQRADL----LGHLTGELERLRRAhER 826
Cdd:pfam15921  470 LESTKEMLRKVVEELTAKKMTLESSERtvsdltasLQEKERAIEATNAEitKLRSRVDLklqeLQHLKNEGDHLRNV-QT 548

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  827 ELESMR---QEQD-------QQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARlaQLNVQEENIRKEKqllldaqRQAA 896
Cdd:pfam15921  549 ECEALKlqmAEKDkvieilrQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDR--RLELQEFKILKDK-------KDAK 619

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  897 LEREEATATHQHLEEAKkehthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDvlkEMA 976
Cdd:pfam15921  620 IRELEARVSDLELEKVK-----LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSE---EME 691

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  977 AEMNasphpEPGLHIEDLRKSLDTNKNQeVSSSLSLSKEEIDLSMESVRQFLSAEGV--AVRNAKEFLVRQTRSMRRRQT 1054
Cdd:pfam15921  692 TTTN-----KLKMQLKSAQSELEQTRNT-LKSMEGSDGHAMKVAMGMQKQITAKRGQidALQSKIQFLEEAMTNANKEKH 765

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907196499 1055 ALKAAQQHWRHELASAQEVDEDLPGT-EVLGNMRKNLNEETRH----LDEMKSAMRKGHDLLKKKEEKLIQLE 1122
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGElEVLRSQERRLKEKVANmevaLDKASLQFAECQDIIQRQEQESVRLK 838

HEC1

COG5185

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...

716-995

4.55e-06

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 51.11 E-value: 4.55e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  716 EVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSsllrdkrqEVEREHERKMDKMKEEHWQEMADAR 795
Cdd:COG5185    282 ENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELE--------ESKRETETGIQNLTAEIEQGQESLT 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  796 ERYEAEeRKQRADLLGhltgeLERLRRAhERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLN 875
Cdd:COG5185    354 ENLEAI-KEEIENIVG-----EVELSKS-SEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQ 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  876 VQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLlETKQQLRRTIDDLRVRRVELESQVDLLQAQsqrLQ 955
Cdd:COG5185    427 RQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYD-EINRSVRSKKEDLNEELTQIESRVSTLKAT---LE 502

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1907196499  956 KHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLR 995
Cdd:COG5185    503 KLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

789-977

5.64e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 50.79 E-value: 5.64e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  789 QEMADARERYEAEERKQRAD-LLGHLTGELERLR---RAHERELESMRQEQDqqLEDLRRRHRDHERKLQDLEVELS--- 861
Cdd:COG3206    155 NALAEAYLEQNLELRREEARkALEFLEEQLPELRkelEEAEAALEEFRQKNG--LVDLSEEAKLLLQQLSELESQLAear 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  862 SRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKK---EHTHLLETKQQLRRTIDDLRVR-- 936
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARytpNHPDVIALRAQIAALRAQLQQEaq 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1907196499  937 --RVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAA 977
Cdd:COG3206    313 riLASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355

Caldesmon

pfam02029

Caldesmon;

635-943

9.42e-06

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 49.87 E-value: 9.42e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  635 ERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEaallqlreqlegERKEAVAGLEKKHSAELEQLCSSLEAKH 714
Cdd:pfam02029    4 EEEAARERRRRAREERRRQKEEEEPSGQVTESVEPNEHNS------------YEEDSELKPSGQGGLDEEEAFLDRTAKR 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  715 QE-VISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVErEHERKMDKMKEEHW-QEMA 792
Cdd:pfam02029   72 EErRQKRLQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEE-ETEIREKEYQENKWsTEVR 150

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  793 DARERYEAEERKQRADllghlTGELERLRRAHERELESMRQEQDQQLED---LRRRHRDHERKLQDLEVELSSRTKDVKA 869
Cdd:pfam02029  151 QAEEEGEEEEDKSEEA-----EEVPTENFAKEEVKDEKIKKEKKVKYESkvfLDQKRGHPEVKSQNGEEEVTKLKVTTKR 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  870 RLAQLNV-----QEENIRKEKQLLLDAQRQ--AALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELES 942
Cdd:pfam02029  226 RQGGLSQsqereEEAEVFLEAEQKLEELRRrrQEKESEEFEKLRQKQQEAELELEELKKKREERRKLLEEEEQRRKQEEA 305


                   .
gi 1907196499  943 Q 943
Cdd:pfam02029  306 E 306

pfam00397

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds ...

58-87

1.03e-05

WW domain; The WW domain is a protein module with two highly conserved tryptophans that binds proline-rich peptide motifs in vitro.

Pssm-ID: 459800 [Multi-domain] Cd Length: 30 Bit Score: 43.26 E-value: 1.03e-05

                           10        20        30
                   ....*....|....*....|....*....|
gi 1907196499   58 LPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:pfam00397    1 LPPGWEERWDPDGRVYYYNHETGETQWEKP 30

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

614-970

1.05e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.17 E-value: 1.05e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  614 RTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVA 693
Cdd:pfam01576  325 REQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSE 404

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  694 GLEKKHSAELEQLCSSL------EAKHQEVISSLQKKIEGAQ-------------QKE----EAQLQESLGWAEQRAHQK 750
Cdd:pfam01576  405 HKRKKLEGQLQELQARLseserqRAELAEKLSKLQSELESVSsllneaegkniklSKDvsslESQLQDTQELLQEETRQK 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  751 V---HQVTEYEQELSSLLrdKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdllghltgeLERLRRAHERE 827
Cdd:pfam01576  485 LnlsTRLRQLEDERNSLQ--EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEA---------LEEGKKRLQRE 553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  828 LESMRQ---EQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA------RLAQLNVQEENIRKEKQLLLDAQRQAALE 898
Cdd:pfam01576  554 LEALTQqleEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNlekkqkKFDQMLAEEKAISARYAEERDRAEAEARE 633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  899 RE-EATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRR-------VELESQVDLLQAQSQRLQKHLSSLEAEVQRKQD 970
Cdd:pfam01576  634 KEtRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKddvgknvHELERSKRALEQQVEEMKTQLEELEDELQATED 713

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

641-907

1.14e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.14e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  641 QKSRRALEQLREQLEAEERSAQAAlraekeAEKEAALLQLREQLEgERKEAVAGLEKKHSAELEQlcssleAKHQEVISS 720
Cdd:COG4913    606 FDNRAKLAALEAELAELEEELAEA------EERLEALEAELDALQ-ERREALQRLAEYSWDEIDV------ASAEREIAE 672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  721 LQKKIEGAQQ--KEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSlLRDKRQEVEREHERKMDkmKEEHWQEMADARERY 798
Cdd:COG4913    673 LEAELERLDAssDDLAALEEQLEELEAELEELEEELDELKGEIGR-LEKELEQAEEELDELQD--RLEAAEDLARLELRA 749

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  799 EAEERKQRADLLGHltgeLERLRRAHERELESMRQEQDQQLEDLRRRHRDHERK----LQDLEVELSSRTkDVKARLAQL 874
Cdd:COG4913    750 LLEERFAAALGDAV----ERELRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDADLESLP-EYLALLDRL 824

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1907196499  875 nVQEENIRKE---KQLLLDAQRQ------AALEREEATATHQ 907
Cdd:COG4913    825 -EEDGLPEYEerfKELLNENSIEfvadllSKLRRAIREIKER 865

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

792-982

1.31e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.06 E-value: 1.31e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  792 ADARERYEAEERKQRADLLGHLTGELERLrrahERELESMRQEQDQ---QLEDLRRRHRDHERKLQDLEVELSSRTKDVK 868
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDAL----QAELEELNEEYNElqaELEALQAEIDKLQAEIAEAEAEIEERREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  869 ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEA-----TATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQ 943
Cdd:COG3883     90 ERARALYRSGGSVSYLDVLLGSESFSDFLDRLSAlskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1907196499  944 VDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNAS 982
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

703-1143

1.51e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 49.63 E-value: 1.51e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  703 LEQLCSSLEAKHQEvISSLQKKIEGAQQKEEaQLQESLGWAEQRAHQKVHQVTEYEQELSSLLrDKRQEVEREHERKMdk 782
Cdd:TIGR04523  199 LELLLSNLKKKIQK-NKSLESQISELKKQNN-QLKDNIEKKQQEINEKTTEISNTQTQLNQLK-DEQNKIKKQLSEKQ-- 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  783 mkeehwqemadareryeaEERKQRADLLGHLTGELERLrrahERELESMRQEQDQQL-EDLRRRHRDHERKLQDLEVELS 861
Cdd:TIGR04523  274 ------------------KELEQNNKKIKELEKQLNQL----KSEISDLNNQKEQDWnKELKSELKNQEKKLEEIQNQIS 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  862 SRTKdvkaRLAQLNVQEENIRKEKQlllDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELE 941
Cdd:TIGR04523  332 QNNK----IISQLNEQISQLKKELT---NSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  942 SQVDLLQAQSQRLQKHLSSLEAEVQRkqdvLKEMAAEMNASphpepglhIEDLRKSlDTNKNQEVssslslskEEIDLSM 1021
Cdd:TIGR04523  405 KLNQQKDEQIKKLQQEKELLEKEIER----LKETIIKNNSE--------IKDLTNQ-DSVKELII--------KNLDNTR 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1022 ESVRQFLSAegvavrnakeflvrQTRSMRRRQTALKAAQQhwrhELASAQevdedlpgtevlgNMRKNLNEETRHLDEMK 1101
Cdd:TIGR04523  464 ESLETQLKV--------------LSRSINKIKQNLEQKQK----ELKSKE-------------KELKKLNEEKKELEEKV 512

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1102 SAMRKGHDLLKKKEEKL------IQLE-SSLQEEV-SDEDTLKGSSIKKV 1143
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLesekkeKESKiSDLEDELnKDDFELKKENLEKE 562

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

825-1136

3.49e-05

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.53 E-value: 3.49e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  825 ERELESMRQEQDQQLEDLRRRhrdherkLQDLEVELSS----------RTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ 894
Cdd:TIGR02169  662 PRGGILFSRSEPAELQRLRER-------LEGLKRELSSlqselrrienRLDELSQELSDASRKIGEIEKEIEQLEQEEEK 734

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  895 AALE----REEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESqvDLLQAQSQRLQKHLSSLEAEVQRKQD 970
Cdd:TIGR02169  735 LKERleelEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEA 812

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  971 VLKEMAAEMNASpHPEPGL------HIEDLRKSLDTNKN--QEVSSSLSLSKEEIDLSMESVRQF---LSAEGVAVRNAK 1039
Cdd:TIGR02169  813 RLREIEQKLNRL-TLEKEYlekeiqELQEQRIDLKEQIKsiEKEIENLNGKKEELEEELEELEAAlrdLESRLGDLKKER 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1040 EFLVRQTRSMRRRQTALKAAQQHWRH---------------------ELASAQEVDEDLPGTEVLGNMRKNLNEETRHL- 1097
Cdd:TIGR02169  892 DELEAQLRELERKIEELEAQIEKKRKrlselkaklealeeelseiedPKGEDEEIPEEELSLEDVQAELQRVEEEIRALe 971

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1907196499 1098 -------DEMKSAMRKgHDLLKKKEEKLIQLESSLQEEVSDEDTLK 1136
Cdd:TIGR02169  972 pvnmlaiQEYEEVLKR-LDELKEKRAKLEEERKAILERIEEYEKKK 1016

cd00201

Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; ...

59-89

3.80e-05

Pssm-ID: 238122 [Multi-domain] Cd Length: 31 Bit Score: 41.74 E-value: 3.80e-05

                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907196499   59 PKGWKPCQNITGDLYYFNFDTGQSIWDHPCD 89
Cdd:cd00201      1 PPGWEERWDPDGRVYYYNHNTKETQWEDPRE 31

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

744-971

4.38e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.09 E-value: 4.38e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  744 EQRAHQKVHQVTEYEQELSSLLRDKRQEVErEHERKMDKMKEEHW----QEMADARERYEAEERKQRADLLGHLTgELER 819
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELE-EAEAALEEFRQKNGlvdlSEEAKLLLQQLSELESQLAEARAELA-EAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  820 LRRAHERELESMRQE-----QDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLL---DA 891
Cdd:COG3206    241 RLAALRAQLGSGPDAlpellQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaslEA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  892 QRQAALEREEATAthQHLEEAKKEHTHLLETKQQLRRtiddlrvrrveLESQVDLLQAQSQRLQKHLSslEAEVQRKQDV 971
Cdd:COG3206    321 ELEALQAREASLQ--AQLAQLEARLAELPELEAELRR-----------LEREVEVARELYESLLQRLE--EARLAEALTV 385

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

642-977

4.74e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 48.02 E-value: 4.74e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  642 KSRRALEQLREQLEAEERSAQAALRaekeaekeaaLLQLREQLEgERKEAVAGLEKKHSAELEQLCSSLEA-KHQEVISS 720
Cdd:COG3096    283 LSERALELRRELFGARRQLAEEQYR----------LVEMARELE-ELSARESDLEQDYQAASDHLNLVQTAlRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  721 LQKKIEGAQQKEEAQLQESLGWAEQRAHQKVhQVTEYEQELSSL---LRDKRQEVEREHERKMdkmkeeHWQEMADARER 797
Cdd:COG3096    352 YQEDLEELTERLEEQEEVVEEAAEQLAEAEA-RLEAAEEEVDSLksqLADYQQALDVQQTRAI------QYQQAVQALEK 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  798 yeAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEV---ELSSRTKDVKARlaql 874
Cdd:COG3096    425 --ARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagEVERSQAWQTAR---- 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  875 nvqeENIRKEKQLLLDAQRQAALEREEATAtHQHLEEAKKEHTHLLETKQQLRRTI---DDLRVRRVELESQVDLLQAQS 951
Cdd:COG3096    499 ----ELLRRYRSQQALAQRLQQLRAQLAEL-EQRLRQQQNAERLLEEFCQRIGQQLdaaEELEELLAELEAQLEELEEQA 573

                          330       340
                   ....*....|....*....|....*.
gi 1907196499  952 QRLQKHLSSLEAEVQRKQDVLKEMAA 977
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKELAA 599

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

612-1047

4.82e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.79 E-value: 4.82e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  612 QIRTEQQAALQRLREEAETLQ------KAERASLEQKSRRALEQLrEQLEAEERSAQAALRAEKEAEKEAALLQLREQLE 685
Cdd:pfam05483  328 QLTEEKEAQMEELNKAKAAHSfvvtefEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVE 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  686 GERKEAVAGLEKK---HSAELEQLCSSLEAKHQEVISSLQkkiegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELS 762
Cdd:pfam05483  407 LEELKKILAEDEKlldEKKQFEKIAEELKGKEQELIFLLQ-----AREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELE 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  763 sllRDKRQEVE-REHERKMDKMKEEHWQEMADARERYEAEE------RKQRADLLGHLTgELERLRRAHERELESMRQEQ 835
Cdd:pfam05483  482 ---KEKLKNIElTAHCDKLLLENKELTQEASDMTLELKKHQediincKKQEERMLKQIE-NLEEKEMNLRDELESVREEF 557

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  836 DQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLE----E 911
Cdd:pfam05483  558 IQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNayeiK 637

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  912 AKKEHTHLLETKQQL-------RRTIDDLRVRRVELESQVDLLQA---QSQRLQKHLSsleaevQRKQDVLKEMAAEMNA 981
Cdd:pfam05483  638 VNKLELELASAKQKFeeiidnyQKEIEDKKISEEKLLEEVEKAKAiadEAVKLQKEID------KRCQHKIAEMVALMEK 711

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  982 SPHPEPGLhIEDLRKSLDTNKNQEVSSSLSLSKEEIDLS-----MESVRQFLSAEgvavRNAKEFLVRQTR 1047
Cdd:pfam05483  712 HKHQYDKI-IEERDSELGLYKNKEQEQSSAKAALEIELSnikaeLLSLKKQLEIE----KEEKEKLKMEAK 777

PRK10929

putative mechanosensitive channel protein; Provisional

728-1004

4.82e-05

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 48.13 E-value: 4.82e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  728 AQQKEEAQLQESLGWAE--QRAHQKvhQVTEYEQELSSLLRDKRQEVEREheRKMDKMKEEHWQEMADARERYEAEERKQ 805
Cdd:PRK10929    20 ATAPDEKQITQELEQAKaaKTPAQA--EIVEALQSALNWLEERKGSLERA--KQYQQVIDNFPKLSAELRQQLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  806 RADLLGHLTGELE-RLRRAHERELESMR---QEQD-------------QQLEDLRRRHRDHERKLQDLEvelSSRTKDVK 868
Cdd:PRK10929    96 RSVPPNMSTDALEqEILQVSSQLLEKSRqaqQEQDrareisdslsqlpQQQTEARRQLNEIERRLQTLG---TPNTPLAQ 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  869 ARLAQLNVqEENIRKEKQLLLDAQRQAALEREEATatHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVE--LESqVDL 946
Cdd:PRK10929   173 AQLTALQA-ESAALKALVDELELAQLSANNRQELA--RLRSELAKKRSQQLDAYLQALRNQLNSQRQREAEraLES-TEL 248

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  947 LQAQSQRLQKHLSSlEAEVQRK-QDVLKEMAAEMN--ASPHPEPGLHIEDLRKSLDTNKNQ 1004
Cdd:PRK10929   249 LAEQSGDLPKSIVA-QFKINRElSQALNQQAQRMDliASQQRQAASQTLQVRQALNTLREQ 308

COG1340

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

708-982

5.57e-05

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.83 E-value: 5.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  708 SSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAhQKVHQVTEYEQELSSLLRDKRQEVEREHERKmdKMKEEH 787
Cdd:COG1340      7 SSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRD-ELNAQVKELREEAQELREKRDELNEKVKELK--EERDEL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  788 WQEMADAREryEAEERKQRADLLGHLTGELERLRRAHERElesmrqEQDQQLEDLRRrhrDHERKLQDLEVELSSRTKDV 867
Cdd:COG1340     84 NEKLNELRE--ELDELRKELAELNKAGGSIDKLRKEIERL------EWRQQTEVLSP---EEEKELVEKIKELEKELEKA 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  868 KArlaqlnvqeenIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLL 947
Cdd:COG1340    153 KK-----------ALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEA 221

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1907196499  948 QAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNAS 982
Cdd:COG1340    222 QEKADELHEEIIELQKELRELRKELKKLRKKQRAL 256

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

745-981

6.48e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.64 E-value: 6.48e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  745 QRAHQKVHQ-VTEY---------EQELSsLLRDKRQEVEREHERkmdkmkeehwQEMADARERYEAEERKQRADLLGHLT 814
Cdd:COG3096    812 QRLHQAFSQfVGGHlavafapdpEAELA-ALRQRRSELERELAQ----------HRAQEQQLRQQLDQLKEQLQLLNKLL 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  815 GELERLRRA-HERELESMRQEQDQQLEDLR--RRHRDHERKLQDLEVELSSRTKD---VKARLAQLNVQEENIRKEKQLL 888
Cdd:COG3096    881 PQANLLADEtLADRLEELREELDAAQEAQAfiQQHGKALAQLEPLVAVLQSDPEQfeqLQADYLQAKEQQRRLKQQIFAL 960

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  889 LD-AQRQAALEREEATathQHLEEAKKEHTHLletKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAevqr 967
Cdd:COG3096    961 SEvVQRRPHFSYEDAV---GLLGENSDLNEKL---RARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDA---- 1030

                          250
                   ....*....|....
gi 1907196499  968 KQDVLKEMAAEMNA 981
Cdd:COG3096   1031 KQQTLQELEQELEE 1044

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

687-1119

6.67e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.51 E-value: 6.67e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  687 ERKEAVAGLE--KKHS----AELEQLCSSLEAKHQEVISsLQKKIE--GAQQKEEAQ----LQESLGWAEQRA---HQKV 751
Cdd:pfam10174  269 DREEEIKQMEvyKSHSkfmkNKIDQLKQELSKKESELLA-LQTKLEtlTNQNSDCKQhievLKESLTAKEQRAailQTEV 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  752 HQVTEYEQELSSLLRDKRQEVEREHERKMDKMKE-EHWQEMADARERYEAEERKQRADLLGHLT---GELERLRRAHER- 826
Cdd:pfam10174  348 DALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEiRDLKDMLDVKERKINVLQKKIENLQEQLRdkdKQLAGLKERVKSl 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  827 ------------ELESMRQEQDQQLEDLRRRHRDHERKLQDlevELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQ 894
Cdd:pfam10174  428 qtdssntdtaltTLEEALSEKERIIERLKEQREREDRERLE---ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEH 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  895 AALEREEATATHQHLE------EAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRK 968
Cdd:pfam10174  505 ASSLASSGLKKDSKLKsleiavEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERL 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  969 QDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKnqevssslslskeeidlsmeSVRQFLSAEGVAVRNAKEFLVRQtrs 1048
Cdd:pfam10174  585 LGILREVENEKNDKDKKIAELESLTLRQMKEQNK--------------------KVANIKHGQQEMKKKGAQLLEEA--- 641

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499 1049 mRRRQTALKAAQQHWRHE--LASAQEVDEDLPGTEV-LGNMRKNLNEETRHLDEMKSAMRKG-HDLLKKKEEKLI 1119
Cdd:pfam10174  642 -RRREDNLADNSQQLQLEelMGALEKTRQELDATKArLSSTQQSLAEKDGHLTNLRAERRKQlEEILEMKQEALL 715

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

600-879

6.67e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 47.44 E-value: 6.67e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  600 AQVQSRTEAFENQIRTEQQAALQRLREEAETLQKA---ERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAEKE-- 674
Cdd:pfam09731  142 ESATAVAKEAKDDAIQAVKAHTDSLKEASDTAEISrekATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPEtp 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  675 ----AALLQLREQLEGERKEA--VAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAH 748
Cdd:pfam09731  222 pklpEHLDNVEEKVEKAQSLAklVDQYKELVASERIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSLIAHAHREIDQLSK 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  749 QKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHEREL 828
Cdd:pfam09731  302 KLAELKKREEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHL 381

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907196499  829 ESMRQEQDQQLEdlrrrhRDHERKLQD-LEVELSSRTKDVKARLAQLNVQEE 879
Cdd:pfam09731  382 KDVLVEQEIELQ------REFLQDIKEkVEEERAGRLLKLNELLANLKGLEK 427

mukB

chromosome partition protein MukB;

611-899

6.81e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 6.81e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  611 NQIRTEQQAALQRLREEaetlqkaeraslEQKSRRALEQLREQLEAEERSA-QAALraEKEAEKEAALLQLREQLEgERK 689
Cdd:PRK04863   843 NRRRVELERALADHESQ------------EQQQRSQLEQAKEGLSALNRLLpRLNL--LADETLADRVEEIREQLD-EAE 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  690 EAVAGLEK--KHSAELEQLCSSLEAKHQEvISSLQKKIEGAQQKEEAQLQESLGWAE---QRAH---QKVHQVTEYEQEL 761
Cdd:PRK04863   908 EAKRFVQQhgNALAQLEPIVSVLQSDPEQ-FEQLKQDYQQAQQTQRDAKQQAFALTEvvqRRAHfsyEDAAEMLAKNSDL 986

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  762 SSLLRDKRQEVEREHERKMDKMKE------EHWQEMADARERYEA-----EERKQRADLLG-HLTGELERLRRAHERELe 829
Cdd:PRK04863   987 NEKLRQRLEQAEQERTRAREQLRQaqaqlaQYNQVLASLKSSYDAkrqmlQELKQELQDLGvPADSGAEERARARRDEL- 1065

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907196499  830 smrqeqDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA---RLAQLNVQEENIRKEKQLLLDAQRQAALER 899
Cdd:PRK04863  1066 ------HARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKlerDYHEMREQVVNAKAGWCAVLRLVKDNGVER 1132

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

530-894

9.01e-05

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 9.01e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  530 EEGEEEEEEEEKEEEEEEEEEEEVCQLYQQKEKSLSL--LKAQLQKATAEEKEKEEETKIREEES--RRLVCLRAQVQSR 605
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYqaLLKEKREYEGYELLKEKEALERQKEAieRQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  606 TEAFEnQIRTEQQAALQRLREEAETLqkaeRASLEQKSRRALEQLREqLEAEERSAQAALRAEKEAEkeaallqlrEQLE 685
Cdd:TIGR02169  257 TEEIS-ELEKRLEEIEQLLEELNKKI----KDLGEEEQLRVKEKIGE-LEAEIASLERSIAEKEREL---------EDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  686 GERKEAVAGLEKKhSAELEQLCSSLEAKHQEVIsSLQKKIEGAQQKEEAQLQEsLGWAEQRAHQKVHQVTEYEQELSSLL 765
Cdd:TIGR02169  322 ERLAKLEAEIDKL-LAEIEELEREIEEERKRRD-KLTEEYAELKEELEDLRAE-LEEVDKEFAETRDELKDYREKLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  766 RdKRQEVEREHERKMDKMKEEHwQEMADARERYEAEERKQRAdllghLTGELERLR---RAHERELESMRqeqdQQLEDL 842
Cdd:TIGR02169  399 R-EINELKRELDRLQEELQRLS-EELADLNAAIAGIEAKINE-----LEEEKEDKAleiKKQEWKLEQLA----ADLSKY 467

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907196499  843 RRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIR--KEKQLLLDAQRQ 894
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQ 521

PRK01156

chromosome segregation protein; Provisional

627-976

9.03e-05

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.20 E-value: 9.03e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  627 EAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQ 705
Cdd:PRK01156   330 KLSVLQKDYNDYIKKKSRYDdLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKK 409

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  706 LCSSLEAKHQEV---ISSLQKKIEGAQQKEEaQLQESLGWAEQR----------AHQKVHQVTEYEQELSSLLRDKRQEV 772
Cdd:PRK01156   410 ELNEINVKLQDIsskVSSLNQRIRALRENLD-ELSRNMEMLNGQsvcpvcgttlGEEKSNHIINHYNEKKSRLEEKIREI 488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  773 ERE----HERKMDKMKEEHWQEMADAReRYEAEERK---QRADLlGHLTGELERLRRAHERELESMRQEQDQQLEDLRRR 845
Cdd:PRK01156   489 EIEvkdiDEKIVDLKKRKEYLESEEIN-KSINEYNKiesARADL-EDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSK 566

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  846 HRDH-----ERKLQDLEV------ELSSRTKDVKARLAQLNVQ--------EENIRK----------------EKQLLLD 890
Cdd:PRK01156   567 RTSWlnalaVISLIDIETnrsrsnEIKKQLNDLESRLQEIEIGfpddksyiDKSIREieneannlnnkyneiqENKILIE 646

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  891 AQRQAALEREEATATHQHLEEAKKEHT-HLLETK---QQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQ 966
Cdd:PRK01156   647 KLRGKIDNYKKQIAEIDSIIPDLKEITsRINDIEdnlKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE 726

                          410
                   ....*....|
gi 1907196499  967 RKQDVLKEMA 976
Cdd:PRK01156   727 SMKKIKKAIG 736

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

818-982

9.57e-05

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 45.06 E-value: 9.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  818 ERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKdvKARLAqLNVQEENIRKEKqllldAQRQAAL 897
Cdd:pfam04012   24 EKMLEQAIRDMQSELVKARQALAQTIARQKQLERRLEQQTEQAKKLEE--KAQAA-LTKGNEELAREA-----LAEKKSL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  898 EreeatathQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQA--QSQRLQKHL---------SSLEAEVQ 966
Cdd:pfam04012   96 E--------KQAEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLLKArlKAAKAQEAVqtslgslstSSATDSFE 167

                          170
                   ....*....|....*.
gi 1907196499  967 RKQDVLKEMAAEMNAS 982
Cdd:pfam04012  168 RIEEKIEEREARADAA 183

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

621-1004

9.84e-05

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 9.84e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  621 LQRLREEAETLQKAERASLEQ----------------KSRRALEQ----LREQLEAEERSAQAA----LR----AEKEAE 672
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDlvsskddvgknvheleRSKRALEQqveeMKTQLEELEDELQATedakLRlevnMQALKA 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  673 KEAALLQLREQLEGERKEAVAGLEKKHSAELEQlcsslEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQ--K 750
Cdd:pfam01576  728 QFERDLQARDEQGEEKRRQLVKQVRELEAELED-----ERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQlkK 802

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  751 VH-QVTEYEQELSSLlRDKRQEV---EREHERKMDKMKEE--HWQEMADARERYEAEERKQRADLlghltgelerlrrah 824
Cdd:pfam01576  803 LQaQMKDLQRELEEA-RASRDEIlaqSKESEKKLKNLEAEllQLQEDLAASERARRQAQQERDEL--------------- 866

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  825 ERELESMRQEQDQQLEDLRRRhrdhERKLQDLEVELSSrtkdvkarlAQLNVQEENIRKEKQLLLDAQRQAALEREEATA 904
Cdd:pfam01576  867 ADEIASGASGKSALQDEKRRL----EARIAQLEEELEE---------EQSNTELLNDRLRKSTLQVEQLTTELAAERSTS 933

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  905 thQHLEEAKkehthlletkQQLRRTIDDLRVRRVELESQVdllqaqSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPH 984
Cdd:pfam01576  934 --QKSESAR----------QQLERQNKELKAKLQEMEGTV------KSKFKSSIAALEAKIAQLEEQLEQESRERQAANK 995

                          410       420
                   ....*....|....*....|....*....
gi 1907196499  985 ---------PEPGLHIEDLRKSLDTNKNQ 1004
Cdd:pfam01576  996 lvrrtekklKEVLLQVEDERRHADQYKDQ 1024

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

599-856

1.31e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.87 E-value: 1.31e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIrTEQQAALQRLREEAETLQK--AERASLEQKSrraLEQLREQLEAEERSAQAALRAEKEAEKEAA 676
Cdd:COG3096    845 RSELERELAQHRAQE-QQLRQQLDQLKEQLQLLNKllPQANLLADET---LADRLEELREELDAAQEAQAFIQQHGKALA 920

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  677 LLQ-----LR------EQLEGERKEAVAGLE--KKHSAELEQLCSSLEA-----------KHQEVISSLQKKIEGAqqkE 732
Cdd:COG3096    921 QLEplvavLQsdpeqfEQLQADYLQAKEQQRrlKQQIFALSEVVQRRPHfsyedavgllgENSDLNEKLRARLEQA---E 997

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  733 EAQLQeslgwAEQRAHQKVHQVTEYEQELSSLL--RDKRQEVEREHERKMDKMKeehWQEMADARERyeAEERKQRadll 810
Cdd:COG3096    998 EARRE-----AREQLRQAQAQYSQYNQVLASLKssRDAKQQTLQELEQELEELG---VQADAEAEER--ARIRRDE---- 1063

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1907196499  811 ghLTGELERLrRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDL 856
Cdd:COG3096   1064 --LHEELSQN-RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

555-970

1.45e-04

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.50 E-value: 1.45e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  555 QLYQQKEKS---LSLLKAQLQKATAEEKEKEEETKIREEESRRLVCLRAQVQSRTEAFE-------------NQIRTEQQ 618
Cdd:TIGR00618  383 TLQQQKTTLtqkLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAElcaaaitctaqceKLEKIHLQ 462

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  619 AALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEE--------RSAQAALRAEKEAEKEAALLQLREQLEGERKE 690
Cdd:TIGR00618  463 ESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEpcplcgscIHPNPARQDIDNPGPLTRRMQRGEQTYAQLET 542

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  691 AVAGLEKKHSAELEQLcSSLEAKHQEVISSLQKKiegaqqkeeAQLQESLGWAEQRAHQKVHQVTEYEQELSsllRDKRQ 770
Cdd:TIGR00618  543 SEEDVYHQLTSERKQR-ASLKEQMQEIQQSFSIL---------TQCDNRSKEDIPNLQNITVRLQDLTEKLS---EAEDM 609

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  771 EVEREHERKMDKMKEEHWQEMAdareRYEAEERKQRADLLGHLTGELERLrrAHERELESMRQEQDQQLEDLRRRHRDhE 850
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVR----LHLQQCSQELALKLTALHALQLTL--TQERVREHALSIRVLPKELLASRQLA-L 682

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  851 RKLQDLEVELSSRTKDVKARLAQLNVQEENIRK-----EKQLLLDAQRQAALEREEATATH-----QHLEEAKKEHTHLL 920
Cdd:TIGR00618  683 QKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEydrefNEIENASSSLGSDLAAREDALNQslkelMHQARTVLKARTEA 762

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  921 ETKQQLRRTIDDLRVRRV-ELESQVDLLQAQSQRLQKHLSSLEAEVQRKQD 970
Cdd:TIGR00618  763 HFNNNEEVTAALQTGAELsHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIP 813

smart00456

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds ...

57-87

2.13e-04

Domain with 2 conserved Trp (W) residues; Also known as the WWP or rsp5 domain. Binds proline-rich polypeptides.

Pssm-ID: 197736 [Multi-domain] Cd Length: 33 Bit Score: 39.89 E-value: 2.13e-04

                            10        20        30
                    ....*....|....*....|....*....|.
gi 1907196499    57 PLPKGWKPCQNITGDLYYFNFDTGQSIWDHP 87
Cdd:smart00456    1 PLPPGWEERKDPDGRPYYYNHETKETQWEKP 31

PRK12704

phosphodiesterase; Provisional

603-726

2.24e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 2.24e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  603 QSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRaLEQLREQLEaeERSAQAALRAEKEAEKEAALLQLRE 682
Cdd:PRK12704    48 KKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKR-LLQKEENLD--RKLELLEKREEELEKKEKELEQKQQ 124

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1907196499  683 QLEgERKEAVAGLEKKHSAELEQLC--SSLEAKhQEVISSLQKKIE 726
Cdd:PRK12704   125 ELE-KKEEELEELIEEQLQELERISglTAEEAK-EILLEKVEEEAR 168

Golgin_A5

pfam09787

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...

709-887

2.39e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.

Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 44.75 E-value: 2.39e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  709 SLEAKHQEVISSLQKKIEGAQQKEE--AQLQESLGW------------AEQRAHQKVHQVTEYEQELSSL--LRDKRQEV 772
Cdd:pfam09787    1 NLESAKQELADYKQKAARILQSKEKliASLKEGSGVegldsstaltleLEELRQERDLLREEIQKLRGQIqqLRTELQEL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  773 EREHERKMDKMKEEhwqeMADARERYEAEERKqradllghltgelerlRRAHERELESMRQEQDQQLEDLRR-------R 845
Cdd:pfam09787   81 EAQQQEEAESSREQ----LQELEEQLATERSA----------------RREAEAELERLQEELRYLEEELRRskatlqsR 140

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1907196499  846 HRDHERKLQDLEVELSSRT------KDVKARLAQLNvqEENIRKEKQL 887
Cdd:pfam09787  141 IKDREAEIEKLRNQLTSKSqssssqSELENRLHQLT--ETLIQKQTML 186

RecN

COG0497

DNA repair ATPase RecN [Replication, recombination and repair];

786-982

2.68e-04

DNA repair ATPase RecN [Replication, recombination and repair];

Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 45.45 E-value: 2.68e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  786 EHWQEMADARERYE-----AEERKQRADLLGHLTGELERLR-RAHErelesmrqeqDQQLEDLRRRHRDHER---KLQDL 856
Cdd:COG0497    162 EAYRAWRALKKELEelradEAERARELDLLRFQLEELEAAAlQPGE----------EEELEEERRRLSNAEKlreALQEA 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  857 EVELSSRTKDVKARLAQLNVQEENIRKekqllLDAQRQAALER-EEATAthqHLEEAKKEHTHLLET------------- 922
Cdd:COG0497    232 LEALSGGEGGALDLLGQALRALERLAE-----YDPSLAELAERlESALI---ELEEAASELRRYLDSlefdperleevee 303

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907196499  923 -KQQLRR-------TIDDLRVRRVELESQVDLLQAQSQRLQKhlssLEAEVQRKQDVLKEMAAEMNAS 982
Cdd:COG0497    304 rLALLRRlarkygvTVEELLAYAEELRAELAELENSDERLEE----LEAELAEAEAELLEAAEKLSAA 367

Spc7

smart00787

Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...

817-969

3.18e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.

Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 44.62 E-value: 3.18e-04

                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499   817 LERLRRAHERELESMRQEqDQQLedlrrrhRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRqaa 896
Cdd:smart00787  142 LEGLKEGLDENLEGLKED-YKLL-------MKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAK--- 210

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907196499   897 lerEEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDllQAQSQRLQ------KHLSSLEAEVQRKQ 969
Cdd:smart00787  211 ---EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIA--EAEKKLEQcrgftfKEIEKLKEQLKLLQ 284

CHASE3

COG5278

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

611-1048

3.27e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];

Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 44.90 E-value: 3.27e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  611 NQIRTEQQAALQRLRE--EAETLQKAERASLEQKSRRALEQLREQLEA-EERSAQAALRAEKEAEKEAALLQLREQLEGE 687
Cdd:COG5278     82 EEARAEIDELLAELRSltADNPEQQARLDELEALIDQWLAELEQVIALrRAGGLEAALALVRSGEGKALMDEIRARLLLL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  688 RKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRD 767
Cdd:COG5278    162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  768 KRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHR 847
Cdd:COG5278    242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  848 DHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLR 927
Cdd:COG5278    322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  928 RTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNASPHPEPGLHIEDLRKSLDTNKNQEVS 1007
Cdd:COG5278    402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1907196499 1008 SSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRS 1048
Cdd:COG5278    482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALA 522

PRK11281

mechanosensitive channel MscK;

706-978

6.50e-04

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.52 E-value: 6.50e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  706 LCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGwAEQRAHQKVhqvteYEQELSSLlrDKRQEVEREHErKMDKMKE 785
Cdd:PRK11281    20 LCLSSAFARAASNGDLPTEADVQAQLDALNKQKLLE-AEDKLVQQD-----LEQTLALL--DKIDRQKEETE-QLKQQLA 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  786 EHWQEMADARERYEAEERKQRADLLghltgelERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLqdleVELSSRTK 865
Cdd:PRK11281    91 QAPAKLRQAQAELEALKDDNDEETR-------ETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL----VSLQTQPE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  866 DVKARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKE-HTHLLETKQQLRrtidDLrvrrveLESQV 944
Cdd:PRK11281   160 RAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDlQRKSLEGNTQLQ----DL------LQKQR 229

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1907196499  945 DLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAE 978
Cdd:PRK11281   230 DYLTARIQRLEHQLQLLQEAINSKRLTLSEKTVQ 263

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

547-874

6.79e-04

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 6.79e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  547 EEEEEEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEETKireeesrrlvclrAQVQSRTEAFENQI---RTEQQAALQR 623
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ-------------LRVKEKIGELEAEIaslERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  624 LREEAETLQKAEraSLEQKSRRALEQLREQLEAEERsaqaalraekeaekeaallqLREQLEGERKEAVAGLEKKHSaEL 703
Cdd:TIGR02169  317 LEDAEERLAKLE--AEIDKLLAEIEELEREIEEERK--------------------RRDKLTEEYAELKEELEDLRA-EL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  704 EQLCSSLEAKHQEViSSLQKKIEGAQQKEEaQLQESLGWAEQRAHQKVHQVTEYEQELSSlLRDKRQEVEREHERKMDKM 783
Cdd:TIGR02169  374 EEVDKEFAETRDEL-KDYREKLEKLKREIN-ELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEI 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  784 KEEHWQ--EMADARERYEAEERKQRADLlghltgelerlrRAHERELESMRQEQDqQLEDLRRRHRDHERKLQDLEVELS 861
Cdd:TIGR02169  451 KKQEWKleQLAADLSKYEQELYDLKEEY------------DRVEKELSKLQRELA-EAEAQARASEERVRGGRAVEEVLK 517

                          330
                   ....*....|...
gi 1907196499  862 SRTKDVKARLAQL 874
Cdd:TIGR02169  518 ASIQGVHGTVAQL 530

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

499-974

7.30e-04

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 7.30e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  499 QKEKPQQLEERLWREEEEKEEGEEEEKEDEEEEGEEEEEEEEKEEEEEEEEeeevcQLYQQKEKSLSLLKAQLQKATAEE 578
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAET-----ELCAEAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  579 KEKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRtEQQAALQRL------------REEAETLQKAERASLEQKSRRA 646
Cdd:pfam01576   78 HELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLD-EEEAARQKLqlekvtteakikKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  647 LEQ----LREQLEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLcssleakhQEVISSLQ 722
Cdd:pfam01576  157 LEEriseFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDL--------QEQIAELQ 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  723 KKIE---GAQQKEEAQLQESLGWAEQRAHQK---VHQVTEYEQELSSLLRDkrQEVEREHERKMDKMKEEHWQEMADARE 796
Cdd:pfam01576  229 AQIAelrAQLAKKEEELQAALARLEEETAQKnnaLKKIRELEAQISELQED--LESERAARNKAEKQRRDLGEELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  797 RYE---------AEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQ-------QLEDLRRRHRDHERKLQDLEVEL 860
Cdd:pfam01576  307 ELEdtldttaaqQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQaleelteQLEQAKRNKANLEKAKQALESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  861 SSRTKDVKArLAQLNVQEENIRKEkqllLDAQRQAALEReeatathqhLEEAKKEHTHLLETKQQLRRTIDDLRVRRVEL 940
Cdd:pfam01576  387 AELQAELRT-LQQAKQDSEHKRKK----LEGQLQELQAR---------LSESERQRAELAEKLSKLQSELESVSSLLNEA 452

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1907196499  941 ESqvdllqaQSQRLQKHLSSLEAEVQRKQDVLKE 974
Cdd:pfam01576  453 EG-------KNIKLSKDVSSLESQLQDTQELLQE 479

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

678-1102

7.35e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 44.34 E-value: 7.35e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  678 LQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEvisslqkkIEGAQQKEEAQLQESLGWAEQ-RAHQKVHQVTE 756
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHE--------LEAAKCLKEDMLEDSNTQIEQlRKMMLSHEGVL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  757 yeQELSSLLRDKRQEVERE-HERkmDKMKEEHWQEMADARERYEAEERKQRADLLGHLTgelerlrrAHERELESMRQEQ 835
Cdd:pfam15921  187 --QEIRSILVDFEEASGKKiYEH--DSMSTMHFRSLGSAISKILRELDTEISYLKGRIF--------PVEDQLEALKSES 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  836 DQQLEDLRRRHRDH-ERKLQDLEVELSSRTKDVKARLAQLN-VQEE-NIRKEKQLLLDAQRQAALEREEATATH--QHLE 910
Cdd:pfam15921  255 QNKIELLLQQHQDRiEQLISEHEVEITGLTEKASSARSQANsIQSQlEIIQEQARNQNSMYMRQLSDLESTVSQlrSELR 334

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  911 EAKKEHTHLLEtkqQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQdvlKEMAAEMNASPH-----P 985
Cdd:pfam15921  335 EAKRMYEDKIE---ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE---KELSLEKEQNKRlwdrdT 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  986 EPGLHIEDLRKSLDtNKNQEVSSSL---SLSKEEIDLSMEsvRQFLSAEG------------VAVRNAKEFLVRQTRSMR 1050
Cdd:pfam15921  409 GNSITIDHLRRELD-DRNMEVQRLEallKAMKSECQGQME--RQMAAIQGkneslekvssltAQLESTKEMLRKVVEELT 485

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907196499 1051 RRQTALKAAQQHWRHELASAQEVDEDLPGTEV-LGNMRKNLNEETRHLDEMKS 1102
Cdd:pfam15921  486 AKKMTLESSERTVSDLTASLQEKERAIEATNAeITKLRSRVDLKLQELQHLKN 538

PRK12705

hypothetical protein; Provisional

789-928

8.25e-04

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.54 E-value: 8.25e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  789 QEMADARERYEAEERKQRADLLGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHER---KLQDLEVELSSRTK 865
Cdd:PRK12705    33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDAraeKLDNLENQLEEREK 112

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907196499  866 DVKARLAQLNVQEENIRKEkqllldAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRR 928
Cdd:PRK12705   113 ALSARELELEELEKQLDNE------LYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEE 169

PRK12704

phosphodiesterase; Provisional

825-979

8.53e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 8.53e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  825 ERELESMRQEQDQQLEDlrrrhRDHERKlQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLldaqrqaalereeata 904
Cdd:PRK12704    48 KKEAEAIKKEALLEAKE-----EIHKLR-NEFEKELRERRNELQKLEKRLLQKEENLDRKLELL---------------- 105

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  905 thqhleeaKKEHTHLLETKQQLRRTIDDLRVRRVELEsqvDLLQAQSQRLQkHLSSLEAEvQRKQDVLKEMAAEM 979
Cdd:PRK12704   106 --------EKREEELEKKEKELEQKQQELEKKEEELE---ELIEEQLQELE-RISGLTAE-EAKEILLEKVEEEA 167

DUF5401

Family of unknown function (DUF5401); This is a family of unknown function found in ...

504-833

8.69e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 8.69e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  504 QQLEERLWREEEEKEEgeeeekedeeeegeeeeeeeekeeeeeeeeeeevcqlyQQKEKSLSLL--KAQLQKATAEEKEK 581
Cdd:pfam17380  287 RQQQEKFEKMEQERLR--------------------------------------QEKEEKAREVerRRKLEEAEKARQAE 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  582 EEETKIREEESRRLVCLRAQVQSRTEAfENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRalEQLREQLEAEER-S 660
Cdd:pfam17380  329 MDRQAAIYAEQERMAMERERELERIRQ-EERKRELERIRQEEIAMEISRMRELERLQMERQQKN--ERVRQELEAARKvK 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  661 AQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEGAQQKEEAQLQESl 740
Cdd:pfam17380  406 ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKR- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  741 gwAEQRAHQKVHQVTEYEQELSSLL----RDKRQEVEREHERKMDKMKEEHWQEMADA--RERYEAEERKQRADLLGHLT 814
Cdd:pfam17380  485 --DRKRAEEQRRKILEKELEERKQAmieeERKRKLLEKEMEERQKAIYEEERRREAEEerRKQQEMEERRRIQEQMRKAT 562

                          330
                   ....*....|....*....
gi 1907196499  815 GELERLrRAHERELESMRQ 833
Cdd:pfam17380  563 EERSRL-EAMEREREMMRQ 580

mukB

chromosome partition protein MukB;

758-981

8.92e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 8.92e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  758 EQELSsLLRDKRQEVEREherkmdkmKEEHWQEMADARERYEAEerKQRADLLGHLTGELERLRR-AHERELESMRqEQD 836
Cdd:PRK04863   836 EAELR-QLNRRRVELERA--------LADHESQEQQQRSQLEQA--KEGLSALNRLLPRLNLLADeTLADRVEEIR-EQL 903

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  837 QQLEDLRRRHRDHERKLQDLEVELSSRTKDvKARLAQLnvqEENIRKEKQLLLDAQRQA-ALEREEATATHQHLEEAKKE 915
Cdd:PRK04863   904 DEAEEAKRFVQQHGNALAQLEPIVSVLQSD-PEQFEQL---KQDYQQAQQTQRDAKQQAfALTEVVQRRAHFSYEDAAEM 979

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907196499  916 HTHLLETKQQLRRTIDDLRVRRVELESQvdLLQAQSQRLQKH--LSSLEAEVQRKQDVLKEMAAEMNA 981
Cdd:PRK04863   980 LAKNSDLNEKLRQRLEQAEQERTRAREQ--LRQAQAQLAQYNqvLASLKSSYDAKRQMLQELKQELQD 1045

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

753-888

1.09e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 1.09e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  753 QVTEYEQELSSLlRDKRQEVEREHErKMDKMKEEHWQEMADARERYEAEERKQR----ADLLGHLTGELERLRRAHErEL 828
Cdd:COG1579     32 ELAELEDELAAL-EARLEAAKTELE-DLEKEIKRLELEIEEVEARIKKYEEQLGnvrnNKEYEALQKEIESLKRRIS-DL 108

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  829 ESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLL 888
Cdd:COG1579    109 EDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168

PRK10929

putative mechanosensitive channel protein; Provisional

610-967

1.10e-03

putative mechanosensitive channel protein; Provisional

Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.50 E-value: 1.10e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  610 ENQIRTEQQAAlqrlrEEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAAlraekeaEKEAALLQ-LREQLEGER 688
Cdd:PRK10929    25 EKQITQELEQA-----KAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVI-------DNFPKLSAeLRQQLNNER 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  689 KEAVAGLEKKHSAELEQlcSSLEAKHQEVISSLQkkiegAQQKEEA--QLQESLGWAEQRAHQKVHQVTEYEQELSSLlr 766
Cdd:PRK10929    93 DEPRSVPPNMSTDALEQ--EILQVSSQLLEKSRQ-----AQQEQDRarEISDSLSQLPQQQTEARRQLNEIERRLQTL-- 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  767 DKRQEVEREHERKMDKMkeehwqemadareryEAEERKQRADLLghltgELERLRRAHERELESMR--------QEQDQQ 838
Cdd:PRK10929   164 GTPNTPLAQAQLTALQA---------------ESAALKALVDEL-----ELAQLSANNRQELARLRselakkrsQQLDAY 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  839 LEDLR-----RRHRDHERKLQ----------DLEVELSSRTKDVKARLAQLNVQEENIrkekQLLLDAQRQAA---LERE 900
Cdd:PRK10929   224 LQALRnqlnsQRQREAERALEstellaeqsgDLPKSIVAQFKINRELSQALNQQAQRM----DLIASQQRQAAsqtLQVR 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  901 EATATHQHLEEAKKEHTHLLET-------------KQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR 967
Cdd:PRK10929   300 QALNTLREQSQWLGVSNALGEAlraqvarlpempkPQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLTAEQNR 379

DUF4659

pfam15558

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...

724-968

1.36e-03

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.

Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 42.72 E-value: 1.36e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  724 KIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEyEQELSSLLRDKRQEVEREHERKMDKMKEEHwQEMADARERYEAE-E 802
Cdd:pfam15558   16 RHKEEQRMRELQQQAALAWEELRRRDQKRQETL-ERERRLLLQQSQEQWQAEKEQRKARLGREE-RRRADRREKQVIEkE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  803 RKQRADLLGHLTGELERLRRAHERElESMRQEQDQQL---EDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEE 879
Cdd:pfam15558   94 SRWREQAEDQENQRQEKLERARQEA-EQRKQCQEQRLkekEEELQALREQNSLQLQERLEEACHKRQLKEREEQKKVQEN 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  880 NIRKE-----KQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRtiddlRVRRVELESQVDLLQA--QSQ 952
Cdd:pfam15558  173 NLSELlnhqaRKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEERHRELRE-----KAQKEEEQFQRAKWRAeeKEE 247

                          250
                   ....*....|....*.
gi 1907196499  953 RLQKHLSSLEAEVQRK 968
Cdd:pfam15558  248 ERQEHKEALAELADRK 263

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

560-1115

1.47e-03

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.17 E-value: 1.47e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  560 KEKSLSLLKAQLQKATAEEKEKEEETKIREEESRRLVcLRAQVQSRTEAFENQIRTEQQAALQRLR---EEAETLQKAER 636
Cdd:pfam05483  238 KEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLE-EKTKLQDENLKELIEKKDHLTKELEDIKmslQRSMSTQKALE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  637 ASLeQKSRRALEQLREQLEA--EERSAQAALRAEKEAEKEAALLQLREQLEGERKEAvagleKKHSAELEQLCSSLEAKH 714
Cdd:pfam05483  317 EDL-QIATKTICQLTEEKEAqmEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRL-----EKNEDQLKIITMELQKKS 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  715 QEVISSLQ----KKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEV-EREHERKMDKMKEEHW- 788
Cdd:pfam05483  391 SELEEMTKfknnKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIhDLEIQLTAIKTSEEHYl 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  789 QEMADARERYEAEERKQrADLLGHlTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEvelssrtkDVK 868
Cdd:pfam05483  471 KEVEDLKTELEKEKLKN-IELTAH-CDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIE--------NLE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  869 ARLAQLNVQEENIRKEKQLLLDAQRQAALEREEATATHQHLEEAKKEHTHLLETK-QQLRRTIDDLRVRRVELESQVDLL 947
Cdd:pfam05483  541 EKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKcNNLKKQIENKNKNIEELHQENKAL 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  948 QAQSQRLQKHLSSLEAEVQRKQDVL---KEMAAEMNASPHPEpglhIEDlRKSLDTNKNQEVSSSLSLSKEEIDLSMESV 1024
Cdd:pfam05483  621 KKKGSAENKQLNAYEIKVNKLELELasaKQKFEEIIDNYQKE----IED-KKISEEKLLEEVEKAKAIADEAVKLQKEID 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1025 R--QFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELASAQEVDEDLPGTEVLgNMRKNLNEETRHLDEMKS 1102
Cdd:pfam05483  696 KrcQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELL-SLKKQLEIEKEEKEKLKM 774

                          570
                   ....*....|...
gi 1907196499 1103 AMRKGHDLLKKKE 1115
Cdd:pfam05483  775 EAKENTAILKDKK 787

PRK11637

AmiB activator; Provisional

789-975

1.55e-03

AmiB activator; Provisional

Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 42.76 E-value: 1.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  789 QEMAdARERYEAEERKQRADLLGHLtgelerlrraherelesmrQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVK 868
Cdd:PRK11637    54 QDIA-AKEKSVRQQQQQRASLLAQL-------------------KKQEEAISQASRKLRETQNTLNQLNKQIDELNASIA 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  869 ARLAQLNVQ--------------------------EENIRKEKQL----LLDAQRQAALE-----REEATATHQHLEEAK 913
Cdd:PRK11637   114 KLEQQQAAQerllaaqldaafrqgehtglqlilsgEESQRGERILayfgYLNQARQETIAelkqtREELAAQKAELEEKQ 193

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907196499  914 KEHTHLLETKQQlrrtiddlrvrrveleSQVDLLQAQSQRlQKHLSSLEAEVQRKQDVLKEM 975
Cdd:PRK11637   194 SQQKTLLYEQQA----------------QQQKLEQARNER-KKTLTGLESSLQKDQQQLSEL 238

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

607-726

1.55e-03

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.18 E-value: 1.55e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  607 EAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRA-LEQLREQLEAEERSAQAALRaekeaekeaallQLREQLE 685
Cdd:cd16269    180 EAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEqQRELEQKLEDQERSYEEHLR------------QLKEKME 247

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1907196499  686 GERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIE 726
Cdd:cd16269    248 EERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEEIR 288

PLN02939

transferase, transferring glycosyl groups

821-1127

1.58e-03

transferase, transferring glycosyl groups

Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 1.58e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  821 RRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------RKEKQLLLDAQR 893
Cdd:PLN02939    36 RARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDhnrasmqRDEAIAAIDNEQ 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  894 QAALEREEATATHQhLEEakkehthLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLK 973
Cdd:PLN02939   116 QTNSKDGEQLSDFQ-LED-------LVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  974 eMAAEMNAspHPE-PGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVR-----QFLSAEGVAVRNAKEFLVRqtr 1047
Cdd:PLN02939   188 -LAAQEKI--HVEiLEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLlkddiQFLKAELIEVAETEERVFK--- 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499 1048 sMRRRQTALKAAQQHWRHELASAQE---------VDEDLPGTEVLGNMrknLNEETRHLDEMKSAMRKGHDLLKKKEEkl 1118
Cdd:PLN02939   262 -LEKERSLLDASLRELESKFIVAQEdvsklsplqYDCWWEKVENLQDL---LDRATNQVEKAALVLDQNQDLRDKVDK-- 335


                   ....*....
gi 1907196499 1119 iqLESSLQE 1127
Cdd:PLN02939   336 --LEASLKE 342

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

606-808

1.73e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.14 E-value: 1.73e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  606 TEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKeaekeaallQLREQLE 685
Cdd:TIGR02794   45 PGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAE---------QAAKQAE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  686 GERKEAVaglEKKHSAELEQlcssleAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVteyEQElssll 765
Cdd:TIGR02794  116 EKQKQAE---EAKAKQAAEA------KAKAEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKA---EAE----- 178

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1907196499  766 RDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAD 808
Cdd:TIGR02794  179 AKAKAEAEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAA 221

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

426-806

2.01e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.65 E-value: 2.01e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  426 TLSPVLGGGHWEAQGLDQEEQDDSKSSIAEPQSKHTQGSERQTAEPAAPQKLFSEAILKGMELEEDQRLLLEFQKEKPQQ 505
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  506 LEERLWREEEEKEEGEEEEKEDEEEEGEEEEEEEEKEEEEEEEEE-EEVCQLYQQKEKSLSLLKAQLQKATAEEKEKEEE 584
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEeEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  585 TKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSR-----RALEQLREQLEAEER 659
Cdd:pfam02463  799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERleeeiTKEELLQELLLKEEE 878

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  660 SAQAALRAEKEAEKEAALLQLREQLEGERKEAVagLEKKHSAELEQlcSSLEAKHQEVISSLQKKIEGAQQKEEAQLQES 739
Cdd:pfam02463  879 LEEQKLKDELESKEEKEKEEKKELEEESQKLNL--LEEKENEIEER--IKEEAEILLKYEEEPEELLLEEADEKEKEENN 954

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  740 LGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVEREHERKMDKMKEEhwQEMADARERYEAEERKQR 806
Cdd:pfam02463  955 KEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLE--EEKKKLIRAIIEETCQRL 1019

CCDC22

pfam05667

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...

610-820

2.02e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.

Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 42.32 E-value: 2.02e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  610 ENQIRTEQQAALQRLREEAETLQ------KAERASLEQKSRRALEQLRE-QLEAEERSAQaalraekeaekeaalLQLRE 682
Cdd:pfam05667  326 EEELQQQREEELEELQEQLEDLEssiqelEKEIKKLESSIKQVEEELEElKEQNEELEKQ---------------YKVKK 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  683 QLEGERKEAVAGLEKkhsaeLEQLCSSleakhqevisSLQKKIEGAQQKEEAQlqeslgwaeqrahqkVHQVTEYEQels 762
Cdd:pfam05667  391 KTLDLLPDAEENIAK-----LQALVDA----------SAQRLVELAGQWEKHR---------------VPLIEEYRA--- 437

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907196499  763 slLRDKRQEVEREHERKMDKMKEEHwQEMADAreryeAEERKQRADLLGHLTGELERL 820
Cdd:pfam05667  438 --LKEAKSNKEDESQRKLEEIKELR-EKIKEV-----AEEAKQKEELYKQLVAEYERL 487

PRK12704

phosphodiesterase; Provisional

636-808

2.19e-03

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 2.19e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  636 RASLEQKSRRALEQLREQLEAEERSAQAaLRAEKEAEKEAALLQLREQLEGERKEAVAGLEKkhsaeleqlcssLEAKHQ 715
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEA-IKKEALLEAKEEIHKLRNEFEKELRERRNELQK------------LEKRLL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  716 EVISSLQKKIEGAQQKEEaQLQESlgwaEQRAHQKVHQVTEYEQELSSLLRDKRQEVER------EHERKM--DKMKEEH 787
Cdd:PRK12704    93 QKEENLDRKLELLEKREE-ELEKK----EKELEQKQQELEKKEEELEELIEEQLQELERisgltaEEAKEIllEKVEEEA 167

                          170       180
                   ....*....|....*....|.
gi 1907196499  788 WQEMADARERYEaEERKQRAD 808
Cdd:PRK12704   168 RHEAAVLIKEIE-EEAKEEAD 187

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

624-1136

2.30e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.41 E-value: 2.30e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  624 LREEAETLQKAERASLE---QKSRRALEQLREQLEAE----ERSAQAALRAEKEAEKEAALLQlreqlegERKEAVAGLE 696
Cdd:pfam15921  243 VEDQLEALKSESQNKIElllQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQ-------EQARNQNSMY 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  697 KKHSAELEQLCSSLEAKHQEVISSLQKKIEgaqqkeeaQLQESLGWAEqrahqkvhqvteyeqelssllrdkrqevereh 776
Cdd:pfam15921  316 MRQLSDLESTVSQLRSELREAKRMYEDKIE--------ELEKQLVLAN-------------------------------- 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  777 erkmdkmkeehwQEMADAReryeaEERKQRADLLGHLTGELER-LRRAHERELE-SMRQEQDQQLED-----------LR 843
Cdd:pfam15921  356 ------------SELTEAR-----TERDQFSQESGNLDDQLQKlLADLHKREKElSLEKEQNKRLWDrdtgnsitidhLR 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  844 RRHRDHERKLQDLEVELSSRTKDVKARLAQ--LNVQEENIRKEKQLLLDAQRQAALER-----EEATATHQHLEEAKKEH 916
Cdd:pfam15921  419 RELDDRNMEVQRLEALLKAMKSECQGQMERqmAAIQGKNESLEKVSSLTAQLESTKEMlrkvvEELTAKKMTLESSERTV 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  917 THLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEaEVQRKQDVLKEMAAEMNASphpepglhIEDLRK 996
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR-NVQTECEALKLQMAEKDKV--------IEILRQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  997 SLDtNKNQEV----------SSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHE 1066
Cdd:pfam15921  570 QIE-NMTQLVgqhgrtagamQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV 648

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499 1067 LASAQEVDEDLpgTEVlGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKL-IQLESSLQEEVSDEDTLK 1136
Cdd:pfam15921  649 KDIKQERDQLL--NEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLkMQLKSAQSELEQTRNTLK 716

PspA_IM30

pfam04012

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...

598-741

2.40e-03

Pssm-ID: 461130 [Multi-domain] Cd Length: 215 Bit Score: 40.82 E-value: 2.40e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  598 LRAQVQSRTEAFENQIRTEQQAalqrLREEAETLQKAERASLEQKSR-----RALEQLREQLEAEERSAQAALRaEKEAE 672
Cdd:pfam04012    9 VRANIHEGLDKAEDPEKMLEQA----IRDMQSELVKARQALAQTIARqkqleRRLEQQTEQAKKLEEKAQAALT-KGNEE 83

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907196499  673 KEAALLQLREQLEG--ERKEAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQK-KIEGAQQKEEAQLQESLG 741
Cdd:pfam04012   84 LAREALAEKKSLEKqaEALETQLAQQRSAVEQLRKQLAALETKIQQLKAKKNLlKARLKAAKAQEAVQTSLG 155

DUF4670

pfam15709

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

834-978

2.61e-03

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 42.25 E-value: 2.61e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  834 EQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQlNVQEENIRKEKQLLLDAQRQAalerEEATATHQHLEEAK 913
Cdd:pfam15709  326 EKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRRLQQ-EQLERAEKMREELELEQQRRF----EEIRLRKQRLEEER 400

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907196499  914 KEHTHLlETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAE 978
Cdd:pfam15709  401 QRQEEE-ERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLAEE 464

PHA02562

endonuclease subunit; Provisional

760-978

2.82e-03

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.92 E-value: 2.82e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  760 ELSSLLRDKRQEVEREheRKMDKMKEEHWQEMADARERYEAEERKQRADllghltgELERLRRAHERELESMRQEQdQQL 839
Cdd:PHA02562   167 EMDKLNKDKIRELNQQ--IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE-------NIARKQNKYDELVEEAKTIK-AEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  840 EDLRRRHRDHERKLQDLevelSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQrqaalereEATATHQHLEEAKKEHTHL 919
Cdd:PHA02562   237 EELTDELLNLVMDIEDP----SAALNKLNTAAAKIKSKIEQFQKVIKMYEKGG--------VCPTCTQQISEGPDRITKI 304

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907196499  920 LETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQ----------KHLSSLEAEVQRKQDVLKEMAAE 978
Cdd:PHA02562   305 KDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLelknkistnkQSLITLVDKAKKVKAAIEELQAE 373

CusB_dom_1

pfam00529

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...

618-774

3.16e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.

Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 41.25 E-value: 3.16e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  618 QAALQRLREEAETLQ-KAERASLEQKSRRALEQLREQLEAEERSAQAALRAEKEAekeaaLLQLREQLEGER-KEAVAGL 695
Cdd:pfam00529   64 EAQLAKAQAQVARLQaELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQ-----LAQAQIDLARRRvLAPIGGI 138

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907196499  696 EKKHSAELEQLCSSLEAKHQEVISSLQKkiegAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVER 774
Cdd:pfam00529  139 SRESLVTAGALVAQAQANLLATVAQLDQ----IYVQITQSAAENQAEVRSELSGAQLQIAEAEAELKLAKLDLERTEIR 213

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

826-982

3.25e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 40.58 E-value: 3.25e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  826 RELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKdvKARLAqLNVQEENIRKEKqllldAQRQAALErEEATAT 905
Cdd:COG1842     33 RDMEEDLVEARQALAQVIANQKRLERQLEELEAEAEKWEE--KARLA-LEKGREDLAREA-----LERKAELE-AQAEAL 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  906 HQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQsQRLQKHLSSLEAE--------VQRKQDvlkEMAA 977
Cdd:COG1842    104 EAQLAQLEEQVEKLKEALRQLESKLEELKAKKDTLKARAKAAKAQ-EKVNEALSGIDSDdatsalerMEEKIE---EMEA 179


                   ....*
gi 1907196499  978 EMNAS 982
Cdd:COG1842    180 RAEAA 184

AmyAc_MTSase

cd11336

Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); ...

772-844

3.37e-03

Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Maltooligosyl trehalose synthase (MTSase) domain. MTSase and maltooligosyl trehalose trehalohydrolase (MTHase) work together to produce trehalose. MTSase is responsible for converting the alpha-1,4-glucosidic linkage to an alpha,alpha-1,1-glucosidic linkage at the reducing end of the maltooligosaccharide through an intramolecular transglucosylation reaction, while MTHase hydrolyzes the penultimate alpha-1,4 linkage of the reducing end, resulting in the release of trehalose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.

Pssm-ID: 200475 [Multi-domain] Cd Length: 660 Bit Score: 41.71 E-value: 3.37e-03

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907196499  772 VEREHERKMDKMkeehWQEMADARERYEAEERKQRADLL-GHLTGELERLRRAHERELESMRQEQDQQLEDLRR 844
Cdd:cd11336    291 VDPAGEAALTRL----YRRFTGDPGDFAELVREAKRLVLdTSLAGELNRLARLLGRIAEADRRTRDFTLNALRR 360

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

628-912

3.94e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 3.94e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  628 AETLQKAERASLEQKSRRALEQLREQL-EAEERSAQAALRaekeaekeaaLLQLREQlegerkEAVAGLEKKHSAELEQL 706
Cdd:COG3206    158 AEAYLEQNLELRREEARKALEFLEEQLpELRKELEEAEAA----------LEEFRQK------NGLVDLSEEAKLLLQQL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  707 cSSLEAKhqevISSLQKKIEGAQQKEEaQLQESLGWAEQRAhQKVHQVTEYEQelsslLRDKRQEVEREHERKMDKMKEE 786
Cdd:COG3206    222 -SELESQ----LAEARAELAEAEARLA-ALRAQLGSGPDAL-PELLQSPVIQQ-----LRAQLAELEAELAELSARYTPN 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  787 HwQEMADAREryeaeerkQRADLLGHLTGELERLRRAHERELESMRQeQDQQLEDLRRRHRDHERKLQDLEVELSSRTKD 866
Cdd:COG3206    290 H-PDVIALRA--------QIAALRAQLQQEAQRILASLEAELEALQA-REASLQAQLAQLEARLAELPELEAELRRLERE 359

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1907196499  867 VKARLAQLnvqeenirkekQLLLDAQRQAALEREEATATHQHLEEA 912
Cdd:COG3206    360 VEVARELY-----------ESLLQRLEEARLAEALTVGNVRVIDPA 394

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

753-904

4.00e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 41.40 E-value: 4.00e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  753 QVTEYEQE---LSSLLRDKRQEV-------EREHERKMDKMKEEHWQEMADARERYEAE-ERKQRADLlghlTGELERLR 821
Cdd:COG2268    175 AITDLEDEnnyLDALGRRKIAEIirdariaEAEAERETEIAIAQANREAEEAELEQEREiETARIAEA----EAELAKKK 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  822 RAHERELESMRQEQDQQLEDLRrrhrdhERKLQDLE--VELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQAALER 899
Cdd:COG2268    251 AEERREAETARAEAEAAYEIAE------ANAEREVQrqLEIAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAE 324


                   ....*
gi 1907196499  900 EEATA 904
Cdd:COG2268    325 AEAEA 329

growth_prot_Scy

NF041483

polarized growth protein Scy;

599-955

4.11e-03

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 41.74 E-value: 4.11e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIRTEQQAALQRLREEA---ETLQKAE--RASLEQKSRRALEQLReqleAEERSAQAALRAEKEAEK 673
Cdd:NF041483   116 RLQAELHTEAVQRRQQLDQELAERRQTVEShvnENVAWAEqlRARTESQARRLLDESR----AEAEQALAAARAEAERLA 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  674 EAALLQLREQLEGERKEAVAGLeKKHSAELEQLCSSLEAKHQEVIS-SLQKKIEGAQQKEEA--QLQESLGWAEQRAhqk 750
Cdd:NF041483   192 EEARQRLGSEAESARAEAEAIL-RRARKDAERLLNAASTQAQEATDhAEQLRSSTAAESDQArrQAAELSRAAEQRM--- 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  751 vhqvteyeQELSSLLRDKRQEVerehERKMDKMKEEHWQEMADARERYEAEER---KQRADLLGHLTGELERLRRAHERE 827
Cdd:NF041483   268 --------QEAEEALREARAEA----EKVVAEAKEAAAKQLASAESANEQRTRtakEEIARLVGEATKEAEALKAEAEQA 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  828 LESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRT---------KDVKARLAQLNVQEENIRKEkqllldAQRQAALE 898
Cdd:NF041483   336 LADARAEAEKLVAEAAEKARTVAAEDTAAQLAKAARTaeevltkasEDAKATTRAAAEEAERIRRE------AEAEADRL 409

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  899 REEATATHQHLEEAKKEHThlletkqqlrrtiDDLRVRRVELESQVDLLQAQSQRLQ 955
Cdd:NF041483   410 RGEAADQAEQLKGAAKDDT-------------KEYRAKTVELQEEARRLRGEAEQLR 453

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

556-905

4.44e-03

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 4.44e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  556 LYQQKEKSLSLLKAQLQKATAEEK--EKEEETKIREEESRRLVCLRAQVQSRTEAFENQIRTEQQA----ALQRLREEAE 629
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTSEEhyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDII 523

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  630 TLQKAERASLEQksrraLEQLREQlEAEERSAQAALRAEKEAEKEAALLQLREQLEGERKEAVAGLEK-KHSAELEQLCS 708
Cdd:pfam05483  524 NCKKQEERMLKQ-----IENLEEK-EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKeKQMKILENKCN 597

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  709 SLEAKhqevISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVhQVTEYEQELSSlLRDKRQEVEREHERKMD--KMKEE 786
Cdd:pfam05483  598 NLKKQ----IENKNKNIEELHQENKALKKKGSAENKQLNAYEI-KVNKLELELAS-AKQKFEEIIDNYQKEIEdkKISEE 671

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  787 HWQEMADARERYEAEERKQRADL---LGHLTGELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSsr 863
Cdd:pfam05483  672 KLLEEVEKAKAIADEAVKLQKEIdkrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELS-- 749

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907196499  864 tkDVKARLAQLNVQEENIRKEKQLLldaqrqaALEREEATAT 905
Cdd:pfam05483  750 --NIKAELLSLKKQLEIEKEEKEKL-------KMEAKENTAI 782

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

616-841

4.73e-03

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 4.73e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  616 EQQAALQRLREEAETLQKAERASLEQkSRRALEQLREQLEAEERS------------AQAALRAEKEAEKEAALLQLREQ 683
Cdd:pfam10174  447 EKERIIERLKEQREREDRERLEELES-LKKENKDLKEKVSALQPEltekesslidlkEHASSLASSGLKKDSKLKSLEIA 525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  684 LEGERKEAVA---GLEKKHSAELEQLCS---SLEAKHQEVISSLQKKIEGAQQKEEAQLQESLGWAEQRAHQKVHQVTEY 757
Cdd:pfam10174  526 VEQKKEECSKlenQLKKAHNAEEAVRTNpeiNDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAEL 605

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  758 EQELSSLLRDKRQEVeREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRA-------------- 823
Cdd:pfam10174  606 ESLTLRQMKEQNKKV-ANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQEldatkarlsstqqs 684

                          250       260
                   ....*....|....*....|.
gi 1907196499  824 -HERE--LESMRQEQDQQLED 841
Cdd:pfam10174  685 lAEKDghLTNLRAERRKQLEE 705

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

610-857

4.96e-03

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.49 E-value: 4.96e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  610 ENQIRTEQQAALQRLREEAETLQKA----ERASLEQKSRRALEQLREQLeAEERSAQAALRAEKEAEKEAALLQLREQLE 685
Cdd:TIGR00618  607 EDMLACEQHALLRKLQPEQDLQDVRlhlqQCSQELALKLTALHALQLTL-TQERVREHALSIRVLPKELLASRQLALQKM 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  686 GERKEAVAG----LEKKHSAELEQLCSSLEAKHQ-----EVISSLQKKIEGaqqkEEAQLQESLGWAE-QRAHQKVHQVT 755
Cdd:TIGR00618  686 QSEKEQLTYwkemLAQCQTLLRELETHIEEYDREfneieNASSSLGSDLAA----REDALNQSLKELMhQARTVLKARTE 761

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  756 EYEQELSSLLRDKRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHErELESMRQEQ 835
Cdd:TIGR00618  762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEE-QFLSRLEEK 840

                          250       260
                   ....*....|....*....|..
gi 1907196499  836 DQQLEDLRRRHRDHERKLQDLE 857
Cdd:TIGR00618  841 SATLGEITHQLLKYEECSKQLA 862

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

616-971

5.04e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.48 E-value: 5.04e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  616 EQQAALqrLREEAETL--QKAERASLEQKSRRALEQLREQL------------EAEERSAQAALR--AEKEAEKEAALLQ 679
Cdd:COG3096    784 EKRLEE--LRAERDELaeQYAKASFDVQKLQRLHQAFSQFVgghlavafapdpEAELAALRQRRSelERELAQHRAQEQQ 861

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  680 LREQLEgERKEAVAGLEKKhsaeLEQLCSSLEAKHQEVISSLQKKIEGAQQKEeaqlqeslgwAEQRAHQKvhQVTEYEQ 759
Cdd:COG3096    862 LRQQLD-QLKEQLQLLNKL----LPQANLLADETLADRLEELREELDAAQEAQ----------AFIQQHGK--ALAQLEP 924

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  760 ELSSLLRDKRQ--EVEREHERKMDKMKEEHWQ--EMADARERYEAEERKQRADLLGHLTGELERLRrAHERELESMRQEQ 835
Cdd:COG3096    925 LVAVLQSDPEQfeQLQADYLQAKEQQRRLKQQifALSEVVQRRPHFSYEDAVGLLGENSDLNEKLR-ARLEQAEEARREA 1003

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  836 DQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKA---RLAQLNVQEENirkekqlllDAQRQAALEREEatathqhleea 912
Cdd:COG3096   1004 REQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQEleqELEELGVQADA---------EAEERARIRRDE----------- 1063

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499  913 kkehthlleTKQQLRRTiddlRVRRVELESQVDLLQAQSQRLQKHLSSLEAE--VQRKQDV 971
Cdd:COG3096   1064 ---------LHEELSQN----RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDykQEREQVV 1111

DUF3584

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

680-972

5.23e-03

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.36 E-value: 5.23e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  680 LREQLEGERKEAVAGLEKKHSAELEQLcSSLEAKhqevISSLQKKIEGAQQKEEAQLQEslgwaeQRAHQKvhqvtEYEQ 759
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTL-ESAELR----LSHLHFGYKSDETLIASRQEE------RQETSA-----ELNQ 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  760 ELSSLLRDKRQEVEREHER----KMDKMKEEHWQEMADAR----ERYEAEERKQRADLLGHLTGELERLRRAHERELESm 831
Cdd:pfam12128  291 LLRTLDDQWKEKRDELNGElsaaDAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPSWQSELENLEERLKALTGK- 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  832 rqeqdqqledlrrrHRDHERKLQDLEVELSSRTKDVkarLAQLNVQEENIRKEKQLLLDAQRqAALEREEATATHQHlEE 911
Cdd:pfam12128  370 --------------HQDVTAKYNRRRSKIKEQNNRD---IAGIKDKLAKIREARDRQLAVAE-DDLQALESELREQL-EA 430

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  912 AKKEhthLLETKQQLRRTIDDLRVR--RVELESQVDLLQAQSQ----RLQKHLSSLEAEVQRKQDVL 972
Cdd:pfam12128  431 GKLE---FNEEEYRLKSRLGELKLRlnQATATPELLLQLENFDerieRAREEQEAANAEVERLQSEL 494

DUF4515

pfam14988

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...

771-967

5.31e-03

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.

Pssm-ID: 405647 [Multi-domain] Cd Length: 206 Bit Score: 39.75 E-value: 5.31e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  771 EVEREHERKMDKMKEEHWQEMADAREryEAEERKQR-ADLLGHLTGELERLRRAHERELESMRQEQdQQLEDLRRRHRDH 849
Cdd:pfam14988    7 EYLAKKTEEKQKKIEKLWNQYVQECE--EIERRRQElASRYTQQTAELQTQLLQKEKEQASLKKEL-QALRPFAKLKESQ 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  850 ERKLQDLEVELSSRTKDVKARLAQLNVQeenIRKEKQLLldaQRQAALEREEATATHQHLEEAKKEHTHLLETKQQLRRT 929
Cdd:pfam14988   84 EREIQDLEEEKEKVRAETAEKDREAHLQ---FLKEKALL---EKQLQELRILELGERATRELKRKAQALKLAAKQALSEF 157

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1907196499  930 IDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQR 967
Cdd:pfam14988  158 CRSIKRENRQLQKELLQLIQETQALEAIKSKLENRKQR 195

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

443-1128

5.72e-03

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.11 E-value: 5.72e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  443 QEEQDDSKSSIAEPQSKHTQGSERQTAEPAAPQKLFSEAILKGMELEEDQRLLLEFQKEKPQQLEERLWREEEEKEEGEE 522
Cdd:pfam02463  268 AQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEL 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  523 EEKEDEEEEGEEEEEEEEKEEEEEEEEEEEVCQLYQQ--------KEKSLSLLKAQLQKATAEEKEKEEETKIREEESRR 594
Cdd:pfam02463  348 EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESErlssaaklKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  595 LVCLRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRALEQLREQLEAEERSAQA---ALRAEKEA 671
Cdd:pfam02463  428 ELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEersQKESKARS 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  672 EKEAALLQLREQLEGERKEAVAGLEKKHSAELEQLC-------SSLEAKHQEVISSLQKKIEGAQQKEEAQ----LQESL 740
Cdd:pfam02463  508 GLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVaistaviVEVSATADEVEERQKLVRALTELPLGARklrlLIPKL 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  741 GWAEQRAHQKVHQVTEYEQELSSLLRDKRQEVERE-----HERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTG 815
Cdd:pfam02463  588 KLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAkvvegILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKAS 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  816 ELERLRRAHERELESMRQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENIRKEKQLLLDAQRQA 895
Cdd:pfam02463  668 LSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDE 747

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  896 ALEREEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLsSLEAEVQRKQDVLKEm 975
Cdd:pfam02463  748 EEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL-KEEAELLEEEQLLIE- 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  976 aAEMNASPHPEPGLHIEDLRKSLDTNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVrqtrsmRRRQTA 1055
Cdd:pfam02463  826 -QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKE------EKEKEE 898

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907196499 1056 LKAAQQHWRHELASAQEVDEDLPGTEVLG-NMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEE 1128
Cdd:pfam02463  899 KKELEEESQKLNLLEEKENEIEERIKEEAeILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEEL 972

PRK03918

DNA double-strand break repair ATPase Rad50;

590-963

6.18e-03

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.20 E-value: 6.18e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  590 EESRrlvclRAQVQSRTEAFENQIRTeqqaaLQRLREEAETLQK--AERASLEQKSRRaLEQLREQLEAEERSAQAalRA 667
Cdd:PRK03918   264 LEER-----IEELKKEIEELEEKVKE-----LKELKEKAEEYIKlsEFYEEYLDELRE-IEKRLSRLEEEINGIEE--RI 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  668 EKEAEKEAALLQLREQLEGERKEaVAGLEKKHS---------AELEQLCSSLEAKHQEVISSLQKKIEGAQ---QKEEAQ 735
Cdd:PRK03918   331 KELEEKEERLEELKKKLKELEKR-LEELEERHElyeeakakkEELERLKKRLTGLTPEKLEKELEELEKAKeeiEEEISK 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  736 LQESLGWAEQRAHQKVHQVTEYEQELSS-------LLRDKRQEVEREHERKMDKMKEEhWQEMADARERYEAEERKQRAD 808
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKcpvcgreLTEEHRKELLEEYTAELKRIEKE-LKEIEEKERKLRKELRELEKV 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  809 LLGHltGELERLRRAHE--RELESMRQEQDqqLEDLRRRHRDHE---RKLQDLEVELSS------RTKDVKARLAQLNVQ 877
Cdd:PRK03918   489 LKKE--SELIKLKELAEqlKELEEKLKKYN--LEELEKKAEEYEklkEKLIKLKGEIKSlkkeleKLEELKKKLAELEKK 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  878 EENIRKEKQLLLDAQRQAALER-EEATATHQHLEEAKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQK 956
Cdd:PRK03918   565 LDELEEELAELLKELEELGFESvEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE 644


                   ....*..
gi 1907196499  957 HLSSLEA 963
Cdd:PRK03918   645 LRKELEE 651

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

567-1127

6.49e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 6.49e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  567 LKAQLQKATAEEKEKEEETKIREEesRRLVCLRAQVQSRTEAFENQIRT--EQQAALQRLREEAETLQKAERASLEQKSR 644
Cdd:TIGR00606  267 LDNEIKALKSRKKQMEKDNSELEL--KMEKVFQGTDEQLNDLYHNHQRTvrEKERELVDCQRELEKLNKERRLLNQEKTE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  645 RALEQLREQLEAEERSAQAALRAEKEAEkeaalLQLREQLEGERKEAVAGLEKKHSAEL------------EQLCSSLEA 712
Cdd:TIGR00606  345 LLVEQGRLQLQADRHQEHIRARDSLIQS-----LATRLELDGFERGPFSERQIKNFHTLvierqedeaktaAQLCADLQS 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  713 KH---QEVISSLQKKIEGAQ----------QKEEAQLQESLgWAEQRAHQKVHQVTEYEQELSSLLRD------------ 767
Cdd:TIGR00606  420 KErlkQEQADEIRDEKKGLGrtielkkeilEKKQEELKFVI-KELQQLEGSSDRILELDQELRKAERElskaeknsltet 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  768 KRQEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRADLLGHLTGELERLRRAHER----------------ELESM 831
Cdd:TIGR00606  499 LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRhsdeltsllgyfpnkkQLEDW 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  832 RQEQDQQLEDLRRRHRDHERKLQDLEVELSSRTKDVKARLAQLNVQEENI-------------RKEKQLLLDAQRQAALE 898
Cdd:TIGR00606  579 LHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsqdeesdlERLKEEIEKSSKQRAML 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  899 REEATATHQHLEEAKKEHTHLLETKQQLRRTiddlrvrRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEM--A 976
Cdd:TIGR00606  659 AGATAVYSQFITQLTDENQSCCPVCQRVFQT-------EAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlgL 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  977 AEMNASPHPEPGLHIEDLRksldtNKNQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAvrnakEFLVRQTRSMRRRQTAL 1056
Cdd:TIGR00606  732 APGRQSIIDLKEKEIPELR-----NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA-----KVCLTDVTIMERFQMEL 801

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907196499 1057 KAAQQHWRHELASAQEVDEDLPGTEVlgnmRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQE 1127
Cdd:TIGR00606  802 KDVERKIAQQAAKLQGSDLDRTVQQV----NQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868

PTZ00491

major vault protein; Provisional

728-869

6.67e-03

major vault protein; Provisional

Pssm-ID: 240439 [Multi-domain] Cd Length: 850 Bit Score: 40.77 E-value: 6.67e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  728 AQQKEEAQLQESLGWAEQrahQKVHQVTEYEQELSSLLR--DKRQEVEREHerkmdkmkeehwQEMADARERYEAEERKQ 805
Cdd:PTZ00491   668 ARHQAELLEQEARGRLER---QKMHDKAKAEEQRTKLLElqAESAAVESSG------------QSRAEALAEAEARLIEA 732

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907196499  806 RADLlghltgELERLR-RAH----ERELESMRQEQDQQLEdlrrrhrdHERKLQDLEVELSSRTKDVKA 869
Cdd:PTZ00491   733 EAEV------EQAELRaKALrieaEAELEKLRKRQELELE--------YEQAQNELEIAKAKELADIEA 787

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

598-1141

6.93e-03

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 40.96 E-value: 6.93e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  598 LRAQVQSRTEAFENQIRTEQQAaLQRLREEAETLQKAERAsleqksRRALEQLreqLEAEERSAQAALRAEKEAEKEAAL 677
Cdd:pfam10174   47 LRKEEAARISVLKEQYRVTQEE-NQHLQLTIQALQDELRA------QRDLNQL---LQQDFTTSPVDGEDKFSTPELTEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  678 LQLREQLEGERKEAVAGLEKKHSAELEqlcSSLEAKHQEVIS---SLQKKIEGAQQKEEAQLQESLGWAEQRahqkvhQV 754
Cdd:pfam10174  117 NFRRLQSEHERQAKELFLLRKTLEEME---LRIETQKQTLGArdeSIKKLLEMLQSKGLPKKSGEEDWERTR------RI 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  755 TEYE---QELSSLLRDKrqEVEREHERKMDKMKEEHWQEMADARERYEAEERKQRAdllghlTGELERLRRAHERELESM 831
Cdd:pfam10174  188 AEAEmqlGHLEVLLDQK--EKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTK------ISSLERNIRDLEDEVQML 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  832 RQEQDQQLEDlrrrhrdHERKLQDLEVeLSSRTKDVKARLAQLNvQEENiRKEKQLLLDAQRQAALEREEATaTHQHLEE 911
Cdd:pfam10174  260 KTNGLLHTED-------REEEIKQMEV-YKSHSKFMKNKIDQLK-QELS-KKESELLALQTKLETLTNQNSD-CKQHIEV 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  912 AKKEHTHLLETKQQLRRTIDDLRVRRVELESQVDLLQAQSQRLQKHLSSLEAEVQRKQDVLKEMAAEMNasphpepGLH- 990
Cdd:pfam10174  329 LKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKIN-------VLQk 401

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  991 -IEDLrksldtnknQEVSSSLSLSKEEIDLSMESVRQFLSAEGVAVRNAKEFLVRQTRSMRRRQTALKAAQQHWRHELAS 1069
Cdd:pfam10174  402 kIENL---------QEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELES 472

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907196499 1070 AQEVDEDLpgTEVLGNMRKNLNEETRHLDEMKSAMRKGHDLLKKKEEKLIQLESSLQEEVSDEDTLKGSSIK 1141
Cdd:pfam10174  473 LKKENKDL--KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKK 542

PRK12705

hypothetical protein; Provisional

598-736

7.07e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.46 E-value: 7.07e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  598 LRAQVQSRTEAFENQIRTEQQAALQRLREEAETLQKAERASLEQKSRRaLEQLREQLEAE-----ERSAQAALRAEKEAE 672
Cdd:PRK12705    38 ILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEER-LVQKEEQLDARaekldNLENQLEEREKALSA 116

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907196499  673 KEAALLQLREQLEGERKEaVAGLEKKHSaeLEQLCSSLEAKHQEvisslQKKIEGAQQKEEAQL 736
Cdd:PRK12705   117 RELELEELEKQLDNELYR-VAGLTPEQA--RKLLLKLLDAELEE-----EKAQRVKKIEEEADL 172

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

690-828

7.10e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.61 E-value: 7.10e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  690 EAVAGLEKKHSAELEQLCSSLEAKHQEVISSLQKKIEgAQQKEEAQLQESLGWAEQRAHQKVHQVTEYEQELSSLLRDKR 769
Cdd:COG2433    380 EALEELIEKELPEEEPEAEREKEHEERELTEEEEEIR-RLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEER 458

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  770 QEVEREHE-RKMDKMKEEHWQEMADARERYEaeerkqradllgHLTGELERLRRAHEREL 828
Cdd:COG2433    459 REIRKDREiSRLDREIERLERELEEERERIE------------ELKRKLERLKELWKLEH 506

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

599-737

7.18e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 40.63 E-value: 7.18e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196499  599 RAQVQSRTEAFENQIRTE---QQAALQRLREEAETLQKAERASLEQ-KSRRALEQLREQLEAEERSAQAALRAEKEAEKE 674
Cdd:COG2268    194 IAEIIRDARIAEAEAEREteiAIAQANREAEEAELEQEREIETARIaEAEAELAKKKAEERREAETARAEAEAAYEIAEA 273

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907196499  675 AALLQLREQLEGERKEAVAGLEKKhSAELEQlcssleakhQEVISSLQKKIEG----AQQKEEAQLQ 737
Cdd:COG2268    274 NAEREVQRQLEIAEREREIELQEK-EAEREE---------AELEADVRKPAEAekqaAEAEAEAEAE 330

mukB