|
Name |
Accession |
Description |
Interval |
E-value |
| CysPc |
cd00044 |
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. ... |
214-538 |
1.27e-104 |
|
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
:
Pssm-ID: 238004 [Multi-domain] Cd Length: 315 Bit Score: 321.97 E-value: 1.27e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 214 TTSKINGVEYVPFMSVDLRERFAYPMPFCdrlgklPLSPKQKTTFSKWVRPEDLTNN-----PTMIY-TVSSFSIKQTIV 287
Cdd:cd00044 1 TLLQICLLSGVLFEDPDFPPNDSSLGFDD------SLSNGQPKKVIEWKRPSEIFADdgnsnPRLFVnGASPSDVCQGIL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 288 SDCSFVASLAISAAYErrfnkKLITSIIYPqnkDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHkGELLCSYSNNK 367
Cdd:cd00044 75 GDCWFLAALAALAERP-----ELLKRVIPP---DQSFEENYAGIYHFRFWKNGEWVEVVIDDRLPTSN-GGLLFMHSRDR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 368 SELWVSLIEKAYMKVMGGYDF-PGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYqRFHKGDVLITASTGVMTE 446
Cdd:cd00044 146 NELWVALLEKAYAKLHGSYEAlVGGNTAEALEDLTGGPTERIDLKSADASSGDNDLFALLL-SFLQGGSLIGCSTGSRSE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 447 AEGEK-WGLVPTHAYAVLDIREFK--GLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQkylnFDPRTAQKIDNGIFWIS 523
Cdd:cd00044 225 EEARTaNGLVKGHAYSVLDVREVQeeGLRLLRLRNPWGVGEWWGGWSDDSSEWWVIDAE----RKKLLLSGKDDGEFWMS 300
|
330
....*....|....*
gi 1907099255 524 WDDLCQYYDVVYLSW 538
Cdd:cd00044 301 FEDFLRNFDGLYVCN 315
|
|
| MIT super family |
cl00299 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain ... |
85-157 |
1.15e-44 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar sorting proteins and others. The molecular function of the MIT domain is unclear.
The actual alignment was detected with superfamily member cd02680:
Pssm-ID: 469712 Cd Length: 75 Bit Score: 154.39 E-value: 1.15e-44
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 85 LDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKP 157
Cdd:cd02680 1 LDLERAHFLVTQAFDEDEKGNAEEAIELYTEAVELCINTSNETMDQALQTKLKQLARQALDRAEALKESMSKA 73
|
|
| calpain_III |
smart00720 |
calpain_III domain; |
593-716 |
1.90e-39 |
|
calpain_III domain;
:
Pssm-ID: 214786 Cd Length: 143 Bit Score: 142.12 E-value: 1.90e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 593 TLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIDKTGP----LLIEL----------RGPRQYSVGFEVVAVSIMG- 656
Cdd:smart00720 1 WHTKSVQGSWTrGQTAGGCRNYPATFWTNPQFRITLEEPDDddctVLIALmqknrrrlrrKGADFLTIGFAVYKVPKELh 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 657 ---DPGPHGFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTT 716
Cdd:smart00720 81 lrrDFFLSNAPRASSGDYINGREVSERFRLPPGEYVIVPSTFEPNQEGDFLLRVFSEGPFKLT 143
|
|
| MIT_calpain7_1 |
cd02681 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
5-76 |
4.13e-36 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
:
Pssm-ID: 239144 Cd Length: 76 Bit Score: 130.41 E-value: 4.13e-36
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 5 ALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAG----SSLERIQEKINEYLERVQALHSAVQSKST 76
Cdd:cd02681 1 ALERDAVQFARLAVQRDQEGRYSEAVFYYKEAAQLLIYAEMAGtlndSHLKTIQEKSNEYLDRAQALHQLVQGQQG 76
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CysPc |
cd00044 |
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. ... |
214-538 |
1.27e-104 |
|
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
Pssm-ID: 238004 [Multi-domain] Cd Length: 315 Bit Score: 321.97 E-value: 1.27e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 214 TTSKINGVEYVPFMSVDLRERFAYPMPFCdrlgklPLSPKQKTTFSKWVRPEDLTNN-----PTMIY-TVSSFSIKQTIV 287
Cdd:cd00044 1 TLLQICLLSGVLFEDPDFPPNDSSLGFDD------SLSNGQPKKVIEWKRPSEIFADdgnsnPRLFVnGASPSDVCQGIL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 288 SDCSFVASLAISAAYErrfnkKLITSIIYPqnkDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHkGELLCSYSNNK 367
Cdd:cd00044 75 GDCWFLAALAALAERP-----ELLKRVIPP---DQSFEENYAGIYHFRFWKNGEWVEVVIDDRLPTSN-GGLLFMHSRDR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 368 SELWVSLIEKAYMKVMGGYDF-PGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYqRFHKGDVLITASTGVMTE 446
Cdd:cd00044 146 NELWVALLEKAYAKLHGSYEAlVGGNTAEALEDLTGGPTERIDLKSADASSGDNDLFALLL-SFLQGGSLIGCSTGSRSE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 447 AEGEK-WGLVPTHAYAVLDIREFK--GLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQkylnFDPRTAQKIDNGIFWIS 523
Cdd:cd00044 225 EEARTaNGLVKGHAYSVLDVREVQeeGLRLLRLRNPWGVGEWWGGWSDDSSEWWVIDAE----RKKLLLSGKDDGEFWMS 300
|
330
....*....|....*
gi 1907099255 524 WDDLCQYYDVVYLSW 538
Cdd:cd00044 301 FEDFLRNFDGLYVCN 315
|
|
| CysPc |
smart00230 |
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). ... |
223-545 |
1.13e-85 |
|
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). Calcium activated neutral protease (large subunit).
Pssm-ID: 128526 Cd Length: 318 Bit Score: 272.66 E-value: 1.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 223 YVPFMSVDLRERFaypmPFCDRL-----GKLPLSPKQKTtFSKWVRPEDLTNNPTMIY-TVSSFSIKQTIVSDCSFVASL 296
Cdd:smart00230 1 YEALRQYCKESGT----LFEDPLfpannGSLFFSQRQRK-FVVWKRPHEIFENPPFIVgGASRTDICQGVLGDCWLLAAL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 297 AISAAYERrfnkklITSIIYPQNKDGEPeyNPCGKYMVKLHLNGVPRKVIIDDQLPVDhKGELLCSYSNNKSELWVSLIE 376
Cdd:smart00230 76 ASLTLREK------LLDRVIPHDQEFSE--NYAGIFHFRFWRFGKWVDVVIDDRLPTY-NGELVFMHSNSRNEFWSALLE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 377 KAYMKVMGGYDFPGSNSNID-LHALTGWIPERIAMHSDSQTfsKDNSFRMLYQRFHKGdVLITASTGVMTEAEGE---KW 452
Cdd:smart00230 147 KAYAKLNGCYEALKGGSTTEaLEDLTGGVAESIDLKEASKD--PDNLFEDLFKAFERG-SLMGCSIGAGTAVEEEeqkDC 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 453 GLVPTHAYAVLDIRE--FKGLRFIQLKNPWSHLRWKGRYSEnDVKNWT---PELQKYLNFDPRtaqkiDNGIFWISWDDL 527
Cdd:smart00230 224 GLVKGHAYSVTDVREvqGRRQELLRLRNPWGQVEWNGPWSD-DSPEWRsvsASEKKNLGLTFD-----DDGEFWMSFEDF 297
|
330
....*....|....*....
gi 1907099255 528 CQYYDVVYL-SWNPALFKE 545
Cdd:smart00230 298 LRHFDKVEIcNLNPDSLEE 316
|
|
| Peptidase_C2 |
pfam00648 |
Calpain family cysteine protease; |
249-534 |
3.82e-49 |
|
Calpain family cysteine protease;
Pssm-ID: 459889 [Multi-domain] Cd Length: 295 Bit Score: 174.23 E-value: 3.82e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 249 PLSPKQKTTFsKWVRPEDLTNNPTMI-YTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKklitsIIYPqnkDGEPEYN 327
Cdd:pfam00648 16 PPSPPPPRGV-EWKRPKEICSNPQFIvDGASRFDICQGELGDCWLLAAIASLTLNPKLLER-----VVPP---DQSFEEN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 328 PCGKYMVKLHLNGVPRKVIIDDQLPVdHKGELLCSYSNNKSELWVSLIEKAYMKVMGGY-DFPGSNSNIDLHALTGWIPE 406
Cdd:pfam00648 87 YAGIFHFRFWRFGEWVDVVIDDRLPT-RNGKLLFVHSRDKNEFWSALLEKAYAKLHGSYeALKGGSTSEALEDFTGGVAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 407 RIAMHSdsqtfSKDNSFRMLyQRFHKGDVLITASTGVMTEAEGEKW---GLVPTHAYAVLDIRE----FKGLRFIQLKNP 479
Cdd:pfam00648 166 SYDLKE-----PPPNLFEIL-LKALERGSLMGCSIDATSAAEEEARtpnGLVKGHAYSVTGVRKvnlkGGKVRLIRLRNP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907099255 480 WSHLRWKGRYSENDvKNW---TPELQKYLNFdprtaQKIDNGIFWISWDDLCQYYDVV 534
Cdd:pfam00648 240 WGEVEWNGAWSDGS-PEWqtvSPEEKEELGL-----TKKDDGEFWMSFEDFLKYFTDL 291
|
|
| MIT_calpain7_2 |
cd02680 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
85-157 |
1.15e-44 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
Pssm-ID: 239143 Cd Length: 75 Bit Score: 154.39 E-value: 1.15e-44
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 85 LDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKP 157
Cdd:cd02680 1 LDLERAHFLVTQAFDEDEKGNAEEAIELYTEAVELCINTSNETMDQALQTKLKQLARQALDRAEALKESMSKA 73
|
|
| calpain_III |
smart00720 |
calpain_III domain; |
593-716 |
1.90e-39 |
|
calpain_III domain;
Pssm-ID: 214786 Cd Length: 143 Bit Score: 142.12 E-value: 1.90e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 593 TLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIDKTGP----LLIEL----------RGPRQYSVGFEVVAVSIMG- 656
Cdd:smart00720 1 WHTKSVQGSWTrGQTAGGCRNYPATFWTNPQFRITLEEPDDddctVLIALmqknrrrlrrKGADFLTIGFAVYKVPKELh 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 657 ---DPGPHGFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTT 716
Cdd:smart00720 81 lrrDFFLSNAPRASSGDYINGREVSERFRLPPGEYVIVPSTFEPNQEGDFLLRVFSEGPFKLT 143
|
|
| MIT_calpain7_1 |
cd02681 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
5-76 |
4.13e-36 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
Pssm-ID: 239144 Cd Length: 76 Bit Score: 130.41 E-value: 4.13e-36
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 5 ALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAG----SSLERIQEKINEYLERVQALHSAVQSKST 76
Cdd:cd02681 1 ALERDAVQFARLAVQRDQEGRYSEAVFYYKEAAQLLIYAEMAGtlndSHLKTIQEKSNEYLDRAQALHQLVQGQQG 76
|
|
| Calpain_III |
cd00214 |
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, ... |
591-718 |
4.68e-34 |
|
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are separated by C2-like domain III. Domain III plays an important role in calcium-induced activation of calpain involving electrostatic interactions with subdomain II. Proposed to mediate calpain's interaction with phospholipids and translocation to cytoplasmic/nuclear membranes. CD includes subdomain III of typical and atypical calpains.
Pssm-ID: 238132 Cd Length: 150 Bit Score: 127.41 E-value: 4.68e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 591 PYTLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIDKTG------PLLIELR----------GPRQYSVGFEVVAVS 653
Cdd:cd00214 1 RKWHTKSFNGEWRrGQTAGGCRNNPDTFWTNPQFRIRVPEPDddegkcTVLIALMqknrrhlrkkGLDLLTIGFHVYKVP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907099255 654 -IMGDPGPHGFQRK-----SSGDYRCGFCYLELEnIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTTQL 718
Cdd:cd00214 81 gENRHLRRDFFLHKaprarSSTFINTREVSLRFR-LPPGEYVIVPSTFEPGEEGEFLLRVFSEKSIKSSEL 150
|
|
| MIT |
smart00745 |
Microtubule Interacting and Trafficking molecule domain; |
87-155 |
2.03e-17 |
|
Microtubule Interacting and Trafficking molecule domain;
Pssm-ID: 197854 Cd Length: 77 Bit Score: 77.35 E-value: 2.03e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLT 155
Cdd:smart00745 5 LSKAKELISKALKADEAGNYEEALELYKKAIEYLLEGIKVESDSKRREALKAKAAEYLDRAEEIKKSLL 73
|
|
| MIT |
pfam04212 |
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric ... |
87-152 |
7.79e-17 |
|
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Pssm-ID: 461228 Cd Length: 66 Bit Score: 75.27 E-value: 7.79e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSE 152
Cdd:pfam04212 1 LSKALELVKKAVEEDNAGNYEEALELYKEALDYLLLALKETKNEERRELLRAKIAEYLERAEELKE 66
|
|
| MIT |
pfam04212 |
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric ... |
10-69 |
1.03e-10 |
|
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Pssm-ID: 461228 Cd Length: 66 Bit Score: 57.94 E-value: 1.03e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 10 AVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLER---IQEKINEYLERVQALHS 69
Cdd:pfam04212 4 ALELVKKAVEEDNAGNYEEALELYKEALDYLLLALKETKNEERrelLRAKIAEYLERAEELKE 66
|
|
| Calpain_III |
pfam01067 |
Calpain large subunit, domain III; The function of the domain III and I are currently unknown. ... |
599-705 |
1.44e-10 |
|
Calpain large subunit, domain III; The function of the domain III and I are currently unknown. Domain II is a cysteine protease and domain IV is a calcium binding domain. Calpains are believed to participate in intracellular signaling pathways mediated by calcium ions.
Pssm-ID: 460050 Cd Length: 136 Bit Score: 59.48 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 599 NGKW-SGQSAGGCGNFQETHKNNPIYQFHIDKTGP--------LLIEL----------RGPRQYSVGFEV--VAVSIMGD 657
Cdd:pfam01067 2 EGRWvRGSTAGGCRNYPDTFWTNPQYRFTLTEPDDdddegectVLVSLmqknrrkqrrLGENLLTIGFAIykVPVELNRK 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1907099255 658 PGPHGFQRKS----SGDY---RCGFCYLELeniPAGIFNIIPSTFLPKQEGPFFL 705
Cdd:pfam01067 82 LRKHFFLTNQpvarSSTYinsREVSLRFRL---PPGEYVIVPSTFEPNEEGEFLL 133
|
|
| MIT |
smart00745 |
Microtubule Interacting and Trafficking molecule domain; |
4-74 |
5.29e-06 |
|
Microtubule Interacting and Trafficking molecule domain;
Pssm-ID: 197854 Cd Length: 77 Bit Score: 44.99 E-value: 5.29e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907099255 4 SALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLER---IQEKINEYLERVQALHSAVQSK 74
Cdd:smart00745 2 RDYLSKAKELISKALKADEAGNYEEALELYKKAIEYLLEGIKVESDSKRreaLKAKAAEYLDRAEEIKKSLLER 75
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
4-150 |
1.76e-05 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 47.03 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 4 SALERDAVQF-ARLAVQRDH--EGRYSEAVFYYKEAAQALIYAEMAGSSLERIQEKINEYLERVQALHSAVQskstdplk 80
Cdd:COG2956 67 KLLERDPDRAeALLELAQDYlkAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK-------- 138
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 81 skhqLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVEL---CLKTSSETADKTLQNKLKQLARQALDRAEAL 150
Cdd:COG2956 139 ----LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLdpdCARALLLLAELYLEQGDYEEAIAALERALEQ 207
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CysPc |
cd00044 |
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. ... |
214-538 |
1.27e-104 |
|
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
Pssm-ID: 238004 [Multi-domain] Cd Length: 315 Bit Score: 321.97 E-value: 1.27e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 214 TTSKINGVEYVPFMSVDLRERFAYPMPFCdrlgklPLSPKQKTTFSKWVRPEDLTNN-----PTMIY-TVSSFSIKQTIV 287
Cdd:cd00044 1 TLLQICLLSGVLFEDPDFPPNDSSLGFDD------SLSNGQPKKVIEWKRPSEIFADdgnsnPRLFVnGASPSDVCQGIL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 288 SDCSFVASLAISAAYErrfnkKLITSIIYPqnkDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHkGELLCSYSNNK 367
Cdd:cd00044 75 GDCWFLAALAALAERP-----ELLKRVIPP---DQSFEENYAGIYHFRFWKNGEWVEVVIDDRLPTSN-GGLLFMHSRDR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 368 SELWVSLIEKAYMKVMGGYDF-PGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYqRFHKGDVLITASTGVMTE 446
Cdd:cd00044 146 NELWVALLEKAYAKLHGSYEAlVGGNTAEALEDLTGGPTERIDLKSADASSGDNDLFALLL-SFLQGGSLIGCSTGSRSE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 447 AEGEK-WGLVPTHAYAVLDIREFK--GLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQkylnFDPRTAQKIDNGIFWIS 523
Cdd:cd00044 225 EEARTaNGLVKGHAYSVLDVREVQeeGLRLLRLRNPWGVGEWWGGWSDDSSEWWVIDAE----RKKLLLSGKDDGEFWMS 300
|
330
....*....|....*
gi 1907099255 524 WDDLCQYYDVVYLSW 538
Cdd:cd00044 301 FEDFLRNFDGLYVCN 315
|
|
| CysPc |
smart00230 |
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). ... |
223-545 |
1.13e-85 |
|
Calpain-like thiol protease family; Calpain-like thiol protease family (peptidase family C2). Calcium activated neutral protease (large subunit).
Pssm-ID: 128526 Cd Length: 318 Bit Score: 272.66 E-value: 1.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 223 YVPFMSVDLRERFaypmPFCDRL-----GKLPLSPKQKTtFSKWVRPEDLTNNPTMIY-TVSSFSIKQTIVSDCSFVASL 296
Cdd:smart00230 1 YEALRQYCKESGT----LFEDPLfpannGSLFFSQRQRK-FVVWKRPHEIFENPPFIVgGASRTDICQGVLGDCWLLAAL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 297 AISAAYERrfnkklITSIIYPQNKDGEPeyNPCGKYMVKLHLNGVPRKVIIDDQLPVDhKGELLCSYSNNKSELWVSLIE 376
Cdd:smart00230 76 ASLTLREK------LLDRVIPHDQEFSE--NYAGIFHFRFWRFGKWVDVVIDDRLPTY-NGELVFMHSNSRNEFWSALLE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 377 KAYMKVMGGYDFPGSNSNID-LHALTGWIPERIAMHSDSQTfsKDNSFRMLYQRFHKGdVLITASTGVMTEAEGE---KW 452
Cdd:smart00230 147 KAYAKLNGCYEALKGGSTTEaLEDLTGGVAESIDLKEASKD--PDNLFEDLFKAFERG-SLMGCSIGAGTAVEEEeqkDC 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 453 GLVPTHAYAVLDIRE--FKGLRFIQLKNPWSHLRWKGRYSEnDVKNWT---PELQKYLNFDPRtaqkiDNGIFWISWDDL 527
Cdd:smart00230 224 GLVKGHAYSVTDVREvqGRRQELLRLRNPWGQVEWNGPWSD-DSPEWRsvsASEKKNLGLTFD-----DDGEFWMSFEDF 297
|
330
....*....|....*....
gi 1907099255 528 CQYYDVVYL-SWNPALFKE 545
Cdd:smart00230 298 LRHFDKVEIcNLNPDSLEE 316
|
|
| Peptidase_C2 |
pfam00648 |
Calpain family cysteine protease; |
249-534 |
3.82e-49 |
|
Calpain family cysteine protease;
Pssm-ID: 459889 [Multi-domain] Cd Length: 295 Bit Score: 174.23 E-value: 3.82e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 249 PLSPKQKTTFsKWVRPEDLTNNPTMI-YTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKklitsIIYPqnkDGEPEYN 327
Cdd:pfam00648 16 PPSPPPPRGV-EWKRPKEICSNPQFIvDGASRFDICQGELGDCWLLAAIASLTLNPKLLER-----VVPP---DQSFEEN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 328 PCGKYMVKLHLNGVPRKVIIDDQLPVdHKGELLCSYSNNKSELWVSLIEKAYMKVMGGY-DFPGSNSNIDLHALTGWIPE 406
Cdd:pfam00648 87 YAGIFHFRFWRFGEWVDVVIDDRLPT-RNGKLLFVHSRDKNEFWSALLEKAYAKLHGSYeALKGGSTSEALEDFTGGVAE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 407 RIAMHSdsqtfSKDNSFRMLyQRFHKGDVLITASTGVMTEAEGEKW---GLVPTHAYAVLDIRE----FKGLRFIQLKNP 479
Cdd:pfam00648 166 SYDLKE-----PPPNLFEIL-LKALERGSLMGCSIDATSAAEEEARtpnGLVKGHAYSVTGVRKvnlkGGKVRLIRLRNP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1907099255 480 WSHLRWKGRYSENDvKNW---TPELQKYLNFdprtaQKIDNGIFWISWDDLCQYYDVV 534
Cdd:pfam00648 240 WGEVEWNGAWSDGS-PEWqtvSPEEKEELGL-----TKKDDGEFWMSFEDFLKYFTDL 291
|
|
| MIT_calpain7_2 |
cd02680 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
85-157 |
1.15e-44 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
Pssm-ID: 239143 Cd Length: 75 Bit Score: 154.39 E-value: 1.15e-44
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 85 LDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKP 157
Cdd:cd02680 1 LDLERAHFLVTQAFDEDEKGNAEEAIELYTEAVELCINTSNETMDQALQTKLKQLARQALDRAEALKESMSKA 73
|
|
| calpain_III |
smart00720 |
calpain_III domain; |
593-716 |
1.90e-39 |
|
calpain_III domain;
Pssm-ID: 214786 Cd Length: 143 Bit Score: 142.12 E-value: 1.90e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 593 TLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIDKTGP----LLIEL----------RGPRQYSVGFEVVAVSIMG- 656
Cdd:smart00720 1 WHTKSVQGSWTrGQTAGGCRNYPATFWTNPQFRITLEEPDDddctVLIALmqknrrrlrrKGADFLTIGFAVYKVPKELh 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 657 ---DPGPHGFQRKSSGDYRCGFCYLELENIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTT 716
Cdd:smart00720 81 lrrDFFLSNAPRASSGDYINGREVSERFRLPPGEYVIVPSTFEPNQEGDFLLRVFSEGPFKLT 143
|
|
| MIT_calpain7_1 |
cd02681 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
5-76 |
4.13e-36 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
Pssm-ID: 239144 Cd Length: 76 Bit Score: 130.41 E-value: 4.13e-36
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 5 ALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAG----SSLERIQEKINEYLERVQALHSAVQSKST 76
Cdd:cd02681 1 ALERDAVQFARLAVQRDQEGRYSEAVFYYKEAAQLLIYAEMAGtlndSHLKTIQEKSNEYLDRAQALHQLVQGQQG 76
|
|
| Calpain_III |
cd00214 |
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, ... |
591-718 |
4.68e-34 |
|
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are separated by C2-like domain III. Domain III plays an important role in calcium-induced activation of calpain involving electrostatic interactions with subdomain II. Proposed to mediate calpain's interaction with phospholipids and translocation to cytoplasmic/nuclear membranes. CD includes subdomain III of typical and atypical calpains.
Pssm-ID: 238132 Cd Length: 150 Bit Score: 127.41 E-value: 4.68e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 591 PYTLSKRINGKWS-GQSAGGCGNFQETHKNNPIYQFHIDKTG------PLLIELR----------GPRQYSVGFEVVAVS 653
Cdd:cd00214 1 RKWHTKSFNGEWRrGQTAGGCRNNPDTFWTNPQFRIRVPEPDddegkcTVLIALMqknrrhlrkkGLDLLTIGFHVYKVP 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907099255 654 -IMGDPGPHGFQRK-----SSGDYRCGFCYLELEnIPAGIFNIIPSTFLPKQEGPFFLDFNSTVPIKTTQL 718
Cdd:cd00214 81 gENRHLRRDFFLHKaprarSSTFINTREVSLRFR-LPPGEYVIVPSTFEPGEEGEFLLRVFSEKSIKSSEL 150
|
|
| MIT |
cd02656 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain ... |
86-157 |
1.14e-19 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar sorting proteins and others. The molecular function of the MIT domain is unclear.
Pssm-ID: 239121 Cd Length: 75 Bit Score: 83.51 E-value: 1.14e-19
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907099255 86 DLERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLTKP 157
Cdd:cd02656 2 LLQQAKELIKQAVKEDEDGNYEEALELYKEALDYLLQALKAEKEPKLRKLLRKKVKEYLDRAEFLKELLKKQ 73
|
|
| MIT |
smart00745 |
Microtubule Interacting and Trafficking molecule domain; |
87-155 |
2.03e-17 |
|
Microtubule Interacting and Trafficking molecule domain;
Pssm-ID: 197854 Cd Length: 77 Bit Score: 77.35 E-value: 2.03e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSEPLT 155
Cdd:smart00745 5 LSKAKELISKALKADEAGNYEEALELYKKAIEYLLEGIKVESDSKRREALKAKAAEYLDRAEEIKKSLL 73
|
|
| MIT |
pfam04212 |
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric ... |
87-152 |
7.79e-17 |
|
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Pssm-ID: 461228 Cd Length: 66 Bit Score: 75.27 E-value: 7.79e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEALSE 152
Cdd:pfam04212 1 LSKALELVKKAVEEDNAGNYEEALELYKEALDYLLLALKETKNEERRELLRAKIAEYLERAEELKE 66
|
|
| MIT |
cd02656 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain ... |
5-75 |
1.83e-12 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar sorting proteins and others. The molecular function of the MIT domain is unclear.
Pssm-ID: 239121 Cd Length: 75 Bit Score: 63.10 E-value: 1.83e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907099255 5 ALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLER---IQEKINEYLERVQALHSAVQSKS 75
Cdd:cd02656 1 ELLQQAKELIKQAVKEDEDGNYEEALELYKEALDYLLQALKAEKEPKLrklLRKKVKEYLDRAEFLKELLKKQK 74
|
|
| MIT |
pfam04212 |
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric ... |
10-69 |
1.03e-10 |
|
MIT (microtubule interacting and transport) domain; The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Pssm-ID: 461228 Cd Length: 66 Bit Score: 57.94 E-value: 1.03e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 10 AVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLER---IQEKINEYLERVQALHS 69
Cdd:pfam04212 4 ALELVKKAVEEDNAGNYEEALELYKEALDYLLLALKETKNEERrelLRAKIAEYLERAEELKE 66
|
|
| Calpain_III |
pfam01067 |
Calpain large subunit, domain III; The function of the domain III and I are currently unknown. ... |
599-705 |
1.44e-10 |
|
Calpain large subunit, domain III; The function of the domain III and I are currently unknown. Domain II is a cysteine protease and domain IV is a calcium binding domain. Calpains are believed to participate in intracellular signaling pathways mediated by calcium ions.
Pssm-ID: 460050 Cd Length: 136 Bit Score: 59.48 E-value: 1.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 599 NGKW-SGQSAGGCGNFQETHKNNPIYQFHIDKTGP--------LLIEL----------RGPRQYSVGFEV--VAVSIMGD 657
Cdd:pfam01067 2 EGRWvRGSTAGGCRNYPDTFWTNPQYRFTLTEPDDdddegectVLVSLmqknrrkqrrLGENLLTIGFAIykVPVELNRK 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1907099255 658 PGPHGFQRKS----SGDY---RCGFCYLELeniPAGIFNIIPSTFLPKQEGPFFL 705
Cdd:pfam01067 82 LRKHFFLTNQpvarSSTYinsREVSLRFRL---PPGEYVIVPSTFEPNEEGEFLL 133
|
|
| MIT_VPS4 |
cd02678 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
87-156 |
2.21e-06 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in intracellular protein transport proteins of the AAA-ATPase family. The molecular function of the MIT domain is unclear.
Pssm-ID: 239141 Cd Length: 75 Bit Score: 45.72 E-value: 2.21e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETAdktlQNKLKQLAR----QALDRAEALSEPLTK 156
Cdd:cd02678 3 LQKAIELVKKAIEEDNAGNYEEALRLYQHALEYFMHALKYEK----NPKSKESIRakctEYLDRAEKLKEYLAK 72
|
|
| MIT |
smart00745 |
Microtubule Interacting and Trafficking molecule domain; |
4-74 |
5.29e-06 |
|
Microtubule Interacting and Trafficking molecule domain;
Pssm-ID: 197854 Cd Length: 77 Bit Score: 44.99 E-value: 5.29e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907099255 4 SALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLER---IQEKINEYLERVQALHSAVQSK 74
Cdd:smart00745 2 RDYLSKAKELISKALKADEAGNYEEALELYKKAIEYLLEGIKVESDSKRreaLKAKAAEYLDRAEEIKKSLLER 75
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
4-150 |
1.76e-05 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 47.03 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 4 SALERDAVQF-ARLAVQRDH--EGRYSEAVFYYKEAAQALIYAEMAGSSLERIQEKINEYLERVQALHSAVQskstdplk 80
Cdd:COG2956 67 KLLERDPDRAeALLELAQDYlkAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK-------- 138
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907099255 81 skhqLDLERAHFLVTQAFDEDEKGNVEDAIELYTEAVEL---CLKTSSETADKTLQNKLKQLARQALDRAEAL 150
Cdd:COG2956 139 ----LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLdpdCARALLLLAELYLEQGDYEEAIAALERALEQ 207
|
|
| MIT_2 |
cd02684 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
87-150 |
3.63e-05 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in proteins with an n-terminal serine/threonine kinase domain. The molecular function of the MIT domain is unclear.
Pssm-ID: 239147 Cd Length: 75 Bit Score: 42.50 E-value: 3.63e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907099255 87 LERAHFLVTQAFDEDEKGNVEDAIELYTEAVELCLKTSSETADKTLQNKLKQLARQALDRAEAL 150
Cdd:cd02684 3 LEKAIALVVQAVKKDQRGDAAAALSLYCSALQYFVPALHYETDAQRKEALRQKVLQYVSRAEEL 66
|
|
| MIT_AAA_Arch |
cd02682 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
6-71 |
5.36e-05 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in mostly archaebacterial AAA-ATPases. The molecular function of the MIT domain is unclear.
Pssm-ID: 239145 Cd Length: 75 Bit Score: 41.75 E-value: 5.36e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907099255 6 LERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQAL---IYAEMAGSSLERIQEKINEYLERVQALHSAV 71
Cdd:cd02682 2 LEEMARKYAINAVKAEKEGNAEDAITNYKKAIEVLsqiVKNYPDSPTRLIYEQMINEYKRRIEVLEKQN 70
|
|
| MIT_VPS4 |
cd02678 |
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This ... |
10-74 |
1.01e-04 |
|
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in intracellular protein transport proteins of the AAA-ATPase family. The molecular function of the MIT domain is unclear.
Pssm-ID: 239141 Cd Length: 75 Bit Score: 41.10 E-value: 1.01e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907099255 10 AVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYA---EMAGSSLERIQEKINEYLERVQALHSAVQSK 74
Cdd:cd02678 6 AIELVKKAIEEDNAGNYEEALRLYQHALEYFMHAlkyEKNPKSKESIRAKCTEYLDRAEKLKEYLAKK 73
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
5-150 |
8.81e-03 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 38.45 E-value: 8.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907099255 5 ALERD---AVQFARLAVQRDHEGRYSEAVFYYKEA-------AQALIYAEMAGSSLERIQEKInEYLERVQALhsavqsk 74
Cdd:COG0457 34 ALELDpddAEALYNLGLAYLRLGRYEEALADYEQAleldpddAEALNNLGLALQALGRYEEAL-EDYDKALEL------- 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907099255 75 stDPLKSKHQLDLERAHFlvtqafdedEKGNVEDAIELYTEAVELclktssETADKTLQNKLKQLARQALDRAEAL 150
Cdd:COG0457 106 --DPDDAEALYNLGLALL---------ELGRYDEAIEAYERALEL------DPDDADALYNLGIALEKLGRYEEAL 164
|
|
| |
