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Conserved domains on  [gi|1907139591|ref|XP_036017779|]
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protein FAM171B isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UPF0560 super family cl11203
Uncharacterized protein family UPF0560; This family of proteins has no known function.
82-681 1.51e-93

Uncharacterized protein family UPF0560; This family of proteins has no known function.


The actual alignment was detected with superfamily member pfam10577:

Pssm-ID: 463154  Cd Length: 811  Bit Score: 307.46  E-value: 1.51e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591  82 LKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMP---SV-- 156
Cdd:pfam10577   3 LKVQVSDNSTLQPLAGATVEVFGNQTSLASGTTGADGVATLRFPYRLGTWVIVTATKRGYVTNSVPWHPSRLPvyaSVsl 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591     --------------------------------------------------------------------------------
Cdd:pfam10577  83 yllperpatlmlyedvvqilsgspgarsqpwvqfqrralrlppnstytnltafltvassqyeiggfpylqglesnstgne 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 157 ----------------------------------------------------------WVHHGWGTVKEHNSHLIWTYDA 178
Cdd:pfam10577 163 swfeltpvaavsvhlltsdgtevqvsgpihvsvplpsdsglkentsvpawrfdpklglWVRSGTGYIQREGSQLTWTYIA 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 179 PHLGYWIAAPSPATLDFGINddfQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNIT---KLEILK 255
Cdd:pfam10577 243 PQLGYWVAAMSPSSSGPVVA---RDITTYHTIFLLAILGGMALLVLILLCLLLYYCRRRCLKPRQQHRKLQlssALDSSK 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 256 RDQTTSTTHIN-----HISSVKTALKAE-DKPQLFNAKTSS--YSPQRKETTKTEAEE--RISMVKTRDNFKIYNEDVSF 325
Cdd:pfam10577 320 KDQATSMSHLNlisgvHLESASSSGEPDmHTPMLKPSFSESrdFQSSRELFFKHKPADksRHSLGNLTPRSKDYRKSVES 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 326 LSVNHNYSRNPTQSLEPSMGSKQPKHINNNLSPSLG-DAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFS 404
Cdd:pfam10577 400 FPLKSARSAETSEGYEPLLHDDYRRSYTSVSSSSEDkDSLYHRRHLTNDSKGYIQDPSPSPPPPFPEREQGIDRKPPDYL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 405 MPEQL-HAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKM--PMH---------------------------------- 447
Cdd:pfam10577 480 LSRSVdHLERPTSLSRPGQLIFCGSVDQMKDNMYRKVRPTLviPAHymrlpgehplsgqalllqtdqqsdlegiqaelsa 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 448 SHVQAPDAREEDIVLEGQQSLPSQTSD------WSRYSNSLLESVSVPGTLNEAVvMTPFSSELQGISEQTLLELskGKP 521
Cdd:pfam10577 560 SHPHQPQQQPQQQQQLSQQGIGQQHLQggegeeWGSQSAGLSESVSIPVLFNDST-LAQMNGELQALTEKKLLEL--GVK 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 522 PHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREK--------TFIKSMHQPKILYLE 593
Cdd:pfam10577 637 PHPRAWFVSLDGRSNAHVRHSYIDLQRAGCNGSNDASLDSGVDMNEPKPGRRGREGRrerkghgsPAPGATAYTKLVYVD 716
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 594 DLDLSSSESGTTVCSPEDPALRHILEGGSgviiEHPGeESPGRKSTVEDfEANTSPTKKRGRPPPLAKRDS--------- 664
Cdd:pfam10577 717 DTEQSSSESRTAVCSPEDNSLTPLLDEGA----ETRG-GTPRRGRSRGN-SSRSSPSESRRDSLTSPEDELpddddggdd 790
                         810       820
                  ....*....|....*....|.
gi 1907139591 665 ----KTNIWKKREERPLIPLN 681
Cdd:pfam10577 791 qgenKKSPWQKREERPLMVFN 811
 
Name Accession Description Interval E-value
UPF0560 pfam10577
Uncharacterized protein family UPF0560; This family of proteins has no known function.
82-681 1.51e-93

Uncharacterized protein family UPF0560; This family of proteins has no known function.


Pssm-ID: 463154  Cd Length: 811  Bit Score: 307.46  E-value: 1.51e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591  82 LKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMP---SV-- 156
Cdd:pfam10577   3 LKVQVSDNSTLQPLAGATVEVFGNQTSLASGTTGADGVATLRFPYRLGTWVIVTATKRGYVTNSVPWHPSRLPvyaSVsl 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591     --------------------------------------------------------------------------------
Cdd:pfam10577  83 yllperpatlmlyedvvqilsgspgarsqpwvqfqrralrlppnstytnltafltvassqyeiggfpylqglesnstgne 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 157 ----------------------------------------------------------WVHHGWGTVKEHNSHLIWTYDA 178
Cdd:pfam10577 163 swfeltpvaavsvhlltsdgtevqvsgpihvsvplpsdsglkentsvpawrfdpklglWVRSGTGYIQREGSQLTWTYIA 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 179 PHLGYWIAAPSPATLDFGINddfQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNIT---KLEILK 255
Cdd:pfam10577 243 PQLGYWVAAMSPSSSGPVVA---RDITTYHTIFLLAILGGMALLVLILLCLLLYYCRRRCLKPRQQHRKLQlssALDSSK 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 256 RDQTTSTTHIN-----HISSVKTALKAE-DKPQLFNAKTSS--YSPQRKETTKTEAEE--RISMVKTRDNFKIYNEDVSF 325
Cdd:pfam10577 320 KDQATSMSHLNlisgvHLESASSSGEPDmHTPMLKPSFSESrdFQSSRELFFKHKPADksRHSLGNLTPRSKDYRKSVES 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 326 LSVNHNYSRNPTQSLEPSMGSKQPKHINNNLSPSLG-DAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFS 404
Cdd:pfam10577 400 FPLKSARSAETSEGYEPLLHDDYRRSYTSVSSSSEDkDSLYHRRHLTNDSKGYIQDPSPSPPPPFPEREQGIDRKPPDYL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 405 MPEQL-HAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKM--PMH---------------------------------- 447
Cdd:pfam10577 480 LSRSVdHLERPTSLSRPGQLIFCGSVDQMKDNMYRKVRPTLviPAHymrlpgehplsgqalllqtdqqsdlegiqaelsa 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 448 SHVQAPDAREEDIVLEGQQSLPSQTSD------WSRYSNSLLESVSVPGTLNEAVvMTPFSSELQGISEQTLLELskGKP 521
Cdd:pfam10577 560 SHPHQPQQQPQQQQQLSQQGIGQQHLQggegeeWGSQSAGLSESVSIPVLFNDST-LAQMNGELQALTEKKLLEL--GVK 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 522 PHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREK--------TFIKSMHQPKILYLE 593
Cdd:pfam10577 637 PHPRAWFVSLDGRSNAHVRHSYIDLQRAGCNGSNDASLDSGVDMNEPKPGRRGREGRrerkghgsPAPGATAYTKLVYVD 716
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 594 DLDLSSSESGTTVCSPEDPALRHILEGGSgviiEHPGeESPGRKSTVEDfEANTSPTKKRGRPPPLAKRDS--------- 664
Cdd:pfam10577 717 DTEQSSSESRTAVCSPEDNSLTPLLDEGA----ETRG-GTPRRGRSRGN-SSRSSPSESRRDSLTSPEDELpddddggdd 790
                         810       820
                  ....*....|....*....|.
gi 1907139591 665 ----KTNIWKKREERPLIPLN 681
Cdd:pfam10577 791 qgenKKSPWQKREERPLMVFN 811
 
Name Accession Description Interval E-value
UPF0560 pfam10577
Uncharacterized protein family UPF0560; This family of proteins has no known function.
82-681 1.51e-93

Uncharacterized protein family UPF0560; This family of proteins has no known function.


Pssm-ID: 463154  Cd Length: 811  Bit Score: 307.46  E-value: 1.51e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591  82 LKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMP---SV-- 156
Cdd:pfam10577   3 LKVQVSDNSTLQPLAGATVEVFGNQTSLASGTTGADGVATLRFPYRLGTWVIVTATKRGYVTNSVPWHPSRLPvyaSVsl 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591     --------------------------------------------------------------------------------
Cdd:pfam10577  83 yllperpatlmlyedvvqilsgspgarsqpwvqfqrralrlppnstytnltafltvassqyeiggfpylqglesnstgne 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 157 ----------------------------------------------------------WVHHGWGTVKEHNSHLIWTYDA 178
Cdd:pfam10577 163 swfeltpvaavsvhlltsdgtevqvsgpihvsvplpsdsglkentsvpawrfdpklglWVRSGTGYIQREGSQLTWTYIA 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 179 PHLGYWIAAPSPATLDFGINddfQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNIT---KLEILK 255
Cdd:pfam10577 243 PQLGYWVAAMSPSSSGPVVA---RDITTYHTIFLLAILGGMALLVLILLCLLLYYCRRRCLKPRQQHRKLQlssALDSSK 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 256 RDQTTSTTHIN-----HISSVKTALKAE-DKPQLFNAKTSS--YSPQRKETTKTEAEE--RISMVKTRDNFKIYNEDVSF 325
Cdd:pfam10577 320 KDQATSMSHLNlisgvHLESASSSGEPDmHTPMLKPSFSESrdFQSSRELFFKHKPADksRHSLGNLTPRSKDYRKSVES 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 326 LSVNHNYSRNPTQSLEPSMGSKQPKHINNNLSPSLG-DAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFS 404
Cdd:pfam10577 400 FPLKSARSAETSEGYEPLLHDDYRRSYTSVSSSSEDkDSLYHRRHLTNDSKGYIQDPSPSPPPPFPEREQGIDRKPPDYL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 405 MPEQL-HAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKM--PMH---------------------------------- 447
Cdd:pfam10577 480 LSRSVdHLERPTSLSRPGQLIFCGSVDQMKDNMYRKVRPTLviPAHymrlpgehplsgqalllqtdqqsdlegiqaelsa 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 448 SHVQAPDAREEDIVLEGQQSLPSQTSD------WSRYSNSLLESVSVPGTLNEAVvMTPFSSELQGISEQTLLELskGKP 521
Cdd:pfam10577 560 SHPHQPQQQPQQQQQLSQQGIGQQHLQggegeeWGSQSAGLSESVSIPVLFNDST-LAQMNGELQALTEKKLLEL--GVK 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 522 PHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREK--------TFIKSMHQPKILYLE 593
Cdd:pfam10577 637 PHPRAWFVSLDGRSNAHVRHSYIDLQRAGCNGSNDASLDSGVDMNEPKPGRRGREGRrerkghgsPAPGATAYTKLVYVD 716
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907139591 594 DLDLSSSESGTTVCSPEDPALRHILEGGSgviiEHPGeESPGRKSTVEDfEANTSPTKKRGRPPPLAKRDS--------- 664
Cdd:pfam10577 717 DTEQSSSESRTAVCSPEDNSLTPLLDEGA----ETRG-GTPRRGRSRGN-SSRSSPSESRRDSLTSPEDELpddddggdd 790
                         810       820
                  ....*....|....*....|.
gi 1907139591 665 ----KTNIWKKREERPLIPLN 681
Cdd:pfam10577 791 qgenKKSPWQKREERPLMVFN 811
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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