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Conserved domains on  [gi|1907205111|ref|XP_036017934|]
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zinc finger MYM-type protein 3 isoform X4 [Mus musculus]

Protein Classification

zf-FCS and DUF3504 domain-containing protein( domain architecture ID 13363461)

protein containing domains PHA03307, TRASH, zf-FCS, and DUF3504

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1220-1387 4.18e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.18e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1220 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1299
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1300 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1376
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205111 1377 MLESMLNRILA 1387
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 39-347 2.46e-09

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.11  E-value: 2.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307    60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307   140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307   218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  260 AHPSLPGDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SS 338
Cdd:PHA03307   298 PSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSS 377


                   ....*....
gi 1907205111  339 MAQRAGRSS 347
Cdd:PHA03307   378 PAASAGRPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 536-575 4.25e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.25e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  536 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 575
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 391-432 3.24e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.24e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205111  391 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 432
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 629-666 1.06e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  629 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 666
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 489-531 1.88e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.88e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205111  489 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 531
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 717-753 2.35e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.35e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  717 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 753
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 758-794 1.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  758 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 794
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-621 7.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  584 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 621
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 671-707 1.76e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.76e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  671 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 707
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
354-390 3.92e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 3.92e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   354 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 390
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 447-483 4.32e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.32e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  447 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 483
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1220-1387 4.18e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.18e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1220 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1299
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1300 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1376
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205111 1377 MLESMLNRILA 1387
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-347 2.46e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.11  E-value: 2.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307    60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307   140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307   218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  260 AHPSLPGDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SS 338
Cdd:PHA03307   298 PSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSS 377


                   ....*....
gi 1907205111  339 MAQRAGRSS 347
Cdd:PHA03307   378 PAASAGRPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 536-575 4.25e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.25e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  536 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 575
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 391-432 3.24e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.24e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205111  391 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 432
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 629-666 1.06e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  629 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 666
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 489-531 1.88e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.88e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205111  489 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 531
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 717-753 2.35e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.35e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  717 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 753
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
541-579 5.33e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.33e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   541 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 579
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 758-794 1.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  758 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 794
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
494-535 2.11e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.05  E-value: 2.11e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1907205111   494 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 535
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
634-670 2.54e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.54e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   634 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 670
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-621 7.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  584 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 621
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
722-754 8.36e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 8.36e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205111   722 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 754
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 671-707 1.76e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.76e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  671 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 707
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
354-390 3.92e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 3.92e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   354 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 390
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 447-483 4.32e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.32e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  447 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 483
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
589-622 6.35e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.35e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205111   589 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 622
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
763-798 8.54e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.54e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   763 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 798
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1220-1387 4.18e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.75  E-value: 4.18e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1220 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1299
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111 1300 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1376
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205111 1377 MLESMLNRILA 1387
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 39-347 2.46e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 62.11  E-value: 2.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111   39 GPYPAMDPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPG 114
Cdd:PHA03307    60 AACDRFEPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  115 GVLDGATELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDS 192
Cdd:PHA03307   140 PVGSPGPPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASA 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  193 PIILESPHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPT 259
Cdd:PHA03307   218 SSPAPAPGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPS 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  260 AHPSLPGDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SS 338
Cdd:PHA03307   298 PSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSS 377


                   ....*....
gi 1907205111  339 MAQRAGRSS 347
Cdd:PHA03307   378 PAASAGRPT 386
PHA03247 PHA03247
large tegument protein UL36; Provisional
 27-321 9.65e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 9.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111   27 GVVTKPEPFNWQGPYPAMDPSDFPSPfDPLTLPEKPLAGDLPVdmefgedlLESQTAPSRGWAPPGP-SPSSGALDLLDT 105
Cdd:PHA03247  2753 GPARPARPPTTAGPPAPAPPAAPAAG-PPRRLTRPAVASLSES--------RESLPSPWDPADPPAAvLAPAAALPPAAS 2823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  106 PSGLEKDPGGVLDGATEllglggllyKAPSPPEVDHGPEGTLAwdSGEQTLEPGPGCQTPEV--MPPDPGA---GASPPS 180
Cdd:PHA03247  2824 PAGPLPPPTSAQPTAPP---------PPPGPPPPSLPLGGSVA--PGGDVRRRPPSRSPAAKpaAPARPPVrrlARPAVS 2892

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  181 PEGLLEPLAPDSPIILESPHIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAP---------PSPSVGET-LGDGINSSQ 250
Cdd:PHA03247  2893 RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPttdpagagePSGAVPQPwLGALVPGRV 2972

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  251 SKPGVCTPTAHPSLPgdglTGKEIEKPPERKRSERVR--------RAEP-PKPEVVDSTESIPVSDEDSDA---MVDDPN 318
Cdd:PHA03247  2973 AVPRFRVPQPAPSRE----APASSTPPLTGHSLSRVSswasslalHEETdPPPVSLKQTLWPPDDTEDSDAdslFDSDSE 3048


                   ...
gi 1907205111  319 DED 321
Cdd:PHA03247  3049 RSD 3051
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 76-347 2.76e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.56  E-value: 2.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111   76 DLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDG----ATELLGLGGLLYKAPSPPEVDHGPEGTLAWDS 151
Cdd:PHA03307     9 DLIEAAAEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAvtvvAGAAACDRFEPPTGPPPGPGTEAPANESRSTP 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  152 G--EQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRR----GSPGQEEEHTQG 225
Cdd:PHA03307    89 TwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPpaagASPAAVASDAAS 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  226 QPQSpnAPPSPSVGETLGDGINSSQSKPGVCTPTAHPslPGDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPV 305
Cdd:PHA03307   169 SRQA--ALPLSSPEETARAPSSPPAEPPPSTPPAAAS--PRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSES 244

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1907205111  306 SDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSS 347
Cdd:PHA03307   245 SGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 536-575 4.25e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.25e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  536 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 575
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 391-432 3.24e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.24e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205111  391 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 432
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 629-666 1.06e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.06e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  629 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 666
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 489-531 1.88e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.13  E-value: 1.88e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205111  489 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 531
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 717-753 2.35e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.35e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  717 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 753
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 132-293 4.92e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 4.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  132 KAPSPPEVDHGPEGTLAWDSGEqtlEPGPGCQTPEVMPPDPGAGASPPSP----EGLLE-----------PLAPDSPiil 196
Cdd:PHA03247  2487 RFPFAAGAAPDPGGGGPPDPDA---PPAPSRLAPAILPDEPVGEPVHPRMltwiRGLEElasddagdpppPLPPAAP--- 2560

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  197 eSPHIEEEIPPlatrRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSS--QSKPGVCTPTAHPSLP--------G 266
Cdd:PHA03247  2561 -PAAPDRSVPP----PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPrgPAPPSPLPPDTHAPDPpppspspaA 2635

                          170       180       190
                   ....*....|....*....|....*....|
gi 1907205111  267 DGLTGKEIEKPPERKRSER---VRRAEPPK 293
Cdd:PHA03247  2636 NEPDPHPPPTVPPPERPRDdpaPGRVSRPR 2665
TRASH smart00746
metallochaperone-like domain;
541-579 5.33e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.33e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   541 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 579
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 758-794 1.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  758 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 794
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
494-535 2.11e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.05  E-value: 2.11e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1907205111   494 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 535
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
634-670 2.54e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.54e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   634 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 670
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-621 7.70e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.51  E-value: 7.70e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  584 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 621
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
722-754 8.36e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 8.36e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205111   722 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 754
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 142-331 9.94e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 9.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  142 GPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPE----GLLEPLAPDSPIILESPHIEEEIPPLATRRRG-SP 216
Cdd:PRK07764   599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEAsaapAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAP 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205111  217 GQEEEHTQGQPQSPN---APPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERKRSERVRRA---- 289
Cdd:PRK07764   679 AAPPPAPAPAAPAAPagaAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGApaqp 758

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907205111  290 ---EPPKPEVVDSTESIPVSDEDSDAMVDDpnDEDFVPFRPRRSP 331
Cdd:PRK07764   759 pppPAPAPAAAPAAAPPPSPPSEEEEMAED--DAPSMDDEDRRDA 801
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 671-707 1.76e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.76e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  671 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 707
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
354-390 3.92e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 3.92e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   354 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 390
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 447-483 4.32e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.32e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205111  447 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 483
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
589-622 6.35e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.35e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205111   589 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 622
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
763-798 8.54e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.54e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205111   763 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 798
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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