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Conserved domains on  [gi|452849314|ref|YP_007474982|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Pseudotmethis rubimarginis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.66e-24

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 87.90  E-value: 1.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  3 MFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 452849314 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.66e-24

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 87.90  E-value: 1.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  3 MFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 452849314 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 1.28e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 1.28e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314   4 FSIFTSLFIYFSGVYVFSSkRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDY--FFPVIFLVFSVCEGALGLSILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 452849314  82 RSHGNDFFNSFGL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.66e-24

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 87.90  E-value: 1.66e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  3 MFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 452849314 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 1-97 7.21e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 61.14  E-value: 7.21e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  1 MFMFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00188  1 MFFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSL 80

                        90
                ....*....|....*..
gi 452849314 81 IRSHGNDFFNSFGLSLC 97
Cdd:MTH00188 81 IRSHGSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 4-97 9.21e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 56.01  E-value: 9.21e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  4 FSIFTSLFIYFSGvyvFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFF--PVIFLVFSVCEGALGLSILVSMI 81
Cdd:MTH00125  6 FSLYTAFMLSLLG---LSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTpmPIILLTFSACEAGTGLALLVATT 82

                        90
                ....*....|....*.
gi 452849314 82 RSHGNDFFNSFGLSLC 97
Cdd:MTH00125 83 RTHGSDHLKNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-97 9.61e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 56.01  E-value: 9.61e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  1 MFMFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00149  1 SMFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSL 80

                        90
                ....*....|....*..
gi 452849314 81 IRSHGNDFFNSFGLSLC 97
Cdd:MTH00149 81 IRLHGNDYVSSLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 2-97 9.86e-11

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 53.22  E-value: 9.86e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  2 FMFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFD-YDYFFPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00013  1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANqVNGMLAIVLLTFGACEASLGLSLLVLM 80

                        90
                ....*....|....*..
gi 452849314 81 IRSHGNDFFNSFGLSLC 97
Cdd:MTH00013 81 TRSYGNDMLKSLTSNKC 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-97 8.19e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 51.12  E-value: 8.19e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 452849314 24 RKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYF--FPVIFLVFSVCEGALGLSILVSMIRSHGNDFFNSFGLSLC 97
Cdd:MTH00126 23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFsaAPMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 4-97 3.23e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 49.60  E-value: 3.23e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  4 FSIFTSLFIYFSGvyvFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYFF--PVIFLVFSVCEGALGLSILVSMI 81
Cdd:MTH00067  6 FTFYSAFLLGLMG---LAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFslPMFMLTFSACEASTGLALMVATT 82

                        90
                ....*....|....*.
gi 452849314 82 RSHGNDFFNSFGLSLC 97
Cdd:MTH00067 83 RTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 1.28e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 1.28e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314   4 FSIFTSLFIYFSGVYVFSSkRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDY--FFPVIFLVFSVCEGALGLSILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 452849314  82 RSHGNDFFNSFGL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-97 4.17e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 46.46  E-value: 4.17e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  1 MFMFSIFTSLFIYFSGVYVFsskRKHLLMVLLSLEYIVLSLFLL--IIIYLYSFDYDYFFPVIFLVFSVCEGALGLSILV 78
Cdd:MTH00107  3 LIYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLV 79

                        90
                ....*....|....*....
gi 452849314 79 SMIRSHGNDFFNSFGLSLC 97
Cdd:MTH00107 80 MVSNTYGTDYVQNLNLLQC 98
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-94 9.11e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 42.98  E-value: 9.11e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  3 MFSIFTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDYDYF--FPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00043  2 NIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLL 81

                        90
                ....*....|....
gi 452849314 81 IRSHGNDFFNSFGL 94
Cdd:MTH00043 82 SRNHNSDLVASLNL 95
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-95 5.74e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 41.08  E-value: 5.74e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 452849314  7 FTSLFIYFSGVYVFSSKRKHLLMVLLSLEYIVLSLFLLIIIYLYSFDY--DYFFPVIFLVFSVCEGALGLSILVSMIRSH 84
Cdd:MTH00181  3 FVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTH 82

                        90
                ....*....|.
gi 452849314 85 GNDFFNSFGLS 95
Cdd:MTH00181 83 GSDHLLKFNLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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