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Conserved domains on  [gi|529217154|ref|YP_008378879|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Avahi laniger]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 3.35e-151

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 428.88  E-value: 3.35e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNPK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 3.35e-151

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 428.88  E-value: 3.35e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNPK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-297 1.89e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.85  E-value: 1.89e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   21 MISS-HWLLIWMGLEINMLAI-IPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIY-------- 90
Cdd:TIGR01770 118 LVSSnDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLlflsngml 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   91 -DPLTSTTIIF---ALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSM-------NLDMLLTLAL 159
Cdd:TIGR01770 198 nISLLLLGIVLilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIFLAIIAF 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  160 LSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTM-------FTMLNVYKSTTTLTLST 232
Cdd:TIGR01770 278 LSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMslgafgvLSLLRSYKDEWIEYISD 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 529217154  233 LWN---KNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLV 297
Cdd:TIGR01770 358 FAGlfkTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-283 7.78e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 85.44  E-value: 7.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   23 SSHWLLIWMGLEINMLAIIPILT-KKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTSTT---- 97
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   98 -------IIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLL-TWQKLAPISIM---LQIHPSMNLDMLLTLA--LLSTLI 164
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsLLYLPSSPFIQQILLIlaIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  165 GGWGGLNQTQLRKILAYSSIAHMGWMVVVLM----YCPPLTMLNLLVYLMLTTTMFTM-----LNVYKSTTTLTLSTLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 529217154  236 KNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMV 283
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-298 1.04e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.71  E-value: 1.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  19 ITMISS-HWLLIWMGLEINMLAIIpILT--KKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTS 95
Cdd:COG1007  116 MLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALAA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  96 TT-----IIFALTM-------KLGMTPFHFWVPEVTQG----ITL-------TAGMLLL-------------TWQK-LAP 138
Cdd:COG1007  195 GGansplLLLGLVLvlaglafKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAALlrllveafpglaaDWQLlLAV 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 139 ISIMlqihpSMnldmlltlallstLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPL----TMLNLLVYLMLTTT 214
Cdd:COG1007  275 LAVL-----SM-------------TVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLG 336

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 215 MFTMLNVYKSTTTLTLSTL-----WNKNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLN 289
Cdd:COG1007  337 AFAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416


                 ....*....
gi 529217154 290 LYFYMRLVY 298
Cdd:COG1007  417 AYYYLRVVK 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 3.35e-151

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 428.88  E-value: 3.35e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNPK 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-334 2.61e-118

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 345.64  E-value: 2.61e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSmNLDMLLTLALL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNPK 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00135 320 QLTLPLAISTTATL 333
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-334 3.93e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 322.16  E-value: 3.93e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNPK 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330
                 ....*....|....
gi 529217154 321 KPTlLLPPLIALST 334
Cdd:MTH00112 321 KNT-LTATLTTLST 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-334 8.81e-108

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 318.79  E-value: 8.81e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQHNpK 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00070 320 KTNNLLSLTIILSL 333
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-334 2.43e-81

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 251.43  E-value: 2.43e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKWQhNPK 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWR-TKS 319

                        330
                 ....*....|....
gi 529217154 321 KPTLLLPPLIALST 334
Cdd:MTH00200 320 NSNLLVGLLLLLSI 333
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-306 1.27e-79

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 246.77  E-value: 1.27e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 TGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFP 306
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFP 306
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-330 2.74e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 165.38  E-value: 2.74e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   1 MNPTALMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMy 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  81 tgqwnITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIhpsMNLDMLLTLALL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 161 STLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTI 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 241 TLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLtmfpvSNNTKMKWQHNPK 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLM-----LNYNKNKWNLKKK 307

                        330
                 ....*....|
gi 529217154 321 KPTLLLPPLI 330
Cdd:MTH00160 308 KNKFSLILNF 317
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 11-315 1.31e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 163.52  E-value: 1.31e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  11 MTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNItniy 90
Cdd:MTH00144  11 FLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS---- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  91 dpltSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLA-LLSTLIGGWGG 169
Cdd:MTH00144  87 ----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVIsVLSALVGSIGG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 170 LNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNvYKSTTTLTLSTLWNKNPTITLMILISLL 249
Cdd:MTH00144 163 LNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLW-SGDSGSMKDLGSLKPSYKTGLSIISLLL 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 529217154 250 SLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKW 315
Cdd:MTH00144 242 SLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-309 1.12e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 158.40  E-value: 1.12e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   6 LMPISMTIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWN 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  86 ITniydplTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALLSTLIG 165
Cdd:MTH00011  88 NI------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 166 GWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTITLMIL 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 529217154 246 ISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSN 309
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-300 5.10e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.87  E-value: 5.10e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  12 TIFMGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTitinamytGQWNITNIYD 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMG--------GSLSFSNLYL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  92 PLTSTTIIF-ALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIhpSMNLDMLLTLALLSTLIGGWGGL 170
Cdd:MTH00197  78 SLLSVVLVIlGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFN--SSSFMGLLICSVLSSLIGGIGGM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 171 NQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTMFTMLNVYKSTTTLTLSTLWNKNPTITLMILISLLS 250
Cdd:MTH00197 156 NQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 529217154 251 LGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYST 300
Cdd:MTH00197 236 LGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 4.15e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.48  E-value: 4.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  13 IFMGTTITMISSHWLLIWMGLEINMLAI-IPILTKKNNPRSVEAATKYFLTQATASMLLMMTIT-------------INA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  79 MYTGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNldMLLTLA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 159 LLSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTM----FTMLNVYKSTTTLTLST-- 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFIYIIMsicvFSIILALNVYKNLIIEFsg 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 529217154 233 LWNKNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLV 297
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-297 1.89e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.85  E-value: 1.89e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   21 MISS-HWLLIWMGLEINMLAI-IPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIY-------- 90
Cdd:TIGR01770 118 LVSSnDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLlflsngml 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   91 -DPLTSTTIIF---ALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSM-------NLDMLLTLAL 159
Cdd:TIGR01770 198 nISLLLLGIVLilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIFLAIIAF 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  160 LSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLMLTTTM-------FTMLNVYKSTTTLTLST 232
Cdd:TIGR01770 278 LSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMslgafgvLSLLRSYKDEWIEYISD 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 529217154  233 LWN---KNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLV 297
Cdd:TIGR01770 358 FAGlfkTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 23-298 2.17e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.54  E-value: 2.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  23 SSHWLLIWMGLEINMLAIIpILT--KKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTSTT--- 97
Cdd:MTH00199 116 SINWLSIYLAIELQTLTLF-ILValKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINSILTGDVgki 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  98 -IIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQIHPSMNLDMLLTLALLStlIGGWGGLNQTQLR 176
Cdd:MTH00199 195 lITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSII--YGAIGALNQTKIK 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 177 KILAYSSIAHMGW------------MVVVLMYcppltmlnLLVYLMLTTTMFTMLNVYKSTTTLT--LSTLWNKNPTITL 242
Cdd:MTH00199 273 RLLAYSGIGHMGFilfgvaigsfesIQASLIY--------MIIYVIMSICSFSIILSLKLTKGLIveVSGLSRKNPVIAL 344

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 529217154 243 MILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVY 298
Cdd:MTH00199 345 TLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-283 7.78e-19

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 85.44  E-value: 7.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   23 SSHWLLIWMGLEINMLAIIPILT-KKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTSTT---- 97
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   98 -------IIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLL-TWQKLAPISIM---LQIHPSMNLDMLLTLA--LLSTLI 164
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsLLYLPSSPFIQQILLIlaIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  165 GGWGGLNQTQLRKILAYSSIAHMGWMVVVLM----YCPPLTMLNLLVYLMLTTTMFTM-----LNVYKSTTTLTLSTLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 529217154  236 KNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMV 283
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGV 288
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-298 1.04e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.71  E-value: 1.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  19 ITMISS-HWLLIWMGLEINMLAIIpILT--KKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTS 95
Cdd:COG1007  116 MLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALAA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  96 TT-----IIFALTM-------KLGMTPFHFWVPEVTQG----ITL-------TAGMLLL-------------TWQK-LAP 138
Cdd:COG1007  195 GGansplLLLGLVLvlaglafKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAALlrllveafpglaaDWQLlLAV 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 139 ISIMlqihpSMnldmlltlallstLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPL----TMLNLLVYLMLTTT 214
Cdd:COG1007  275 LAVL-----SM-------------TVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLG 336

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 215 MFTMLNVYKSTTTLTLSTL-----WNKNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLN 289
Cdd:COG1007  337 AFAVILLLSRKGGEAEEIEdlaglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVIS 416


                 ....*....
gi 529217154 290 LYFYMRLVY 298
Cdd:COG1007  417 AYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
21-297 6.25e-15

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 75.24  E-value: 6.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  21 MISS-HWLLIWMGLEINMLAI-IPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNIYDPLTSTT- 97
Cdd:PRK05777 119 MVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKALADGSg 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  98 ----IIFALTM-------KLGMTPFHFWVPEVTQG----ITL-------TAGMLLLT-------------WQK-LAPISI 141
Cdd:PRK05777 199 nsllLLFGLVFllvglafKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAVLLrllvvafgglsedWQQvLAIIAI 278

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 142 MlqihpSMnldmlltlallstLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPL----TMLNLLVYLMLTTTMFT 217
Cdd:PRK05777 279 A-----SM-------------LVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAFG 340

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 218 MLN-VYKSTTTLTLSTLWN----KNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYF 292
Cdd:PRK05777 341 VISlLRRKGGEAESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFY 420


                 ....*
gi 529217154 293 YMRLV 297
Cdd:PRK05777 421 YLRVI 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-301 2.08e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 61.32  E-value: 2.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  15 MGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNITNI----- 89
Cdd:COG0651  118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarla 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  90 -YDPLTSTT----IIFALTMKLGMTPFHFWVPE--------VT---QGITLTAGM--LLLTWQKLAPISIMLQIHPSMnl 151
Cdd:COG0651  198 eLDPGLLLAafalLLVGFGIKAALFPLHFWLPDaypaapspVSallSGLLTKVGVyaILRVLTLLFGADPALFLGTLL-- 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 152 dmlLTLALLSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYL----MLTTTMF----TMLNVYK 223
Cdd:COG0651  276 ---LVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFlaagAIERATG 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 529217154 224 STTTLTLSTLWNKNPTITLMILISLLSLGGLPPLTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTS 301
Cdd:COG0651  353 TRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-334 7.06e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 51.10  E-value: 7.06e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 529217154  291 YFYMRLVYSTSLTMFPVSNNTKMKWQHNPKKPTLLLPPLIALST 334
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSI 44
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 15-192 6.22e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 54.09  E-value: 6.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  15 MGTTITMISSHWLLIWMGLEINMLAIIPILTKKNNPRSV---------EAATKYFLTQATASMLLMMTITINAMYTG-QW 84
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGnEG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  85 NITNIYDPLTSTT-------------IIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLapISIMLQIHPSMNL 151
Cdd:MTH00198 279 MLGTILSATLETTnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 529217154 152 DMLLTLALLSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVV 192
Cdd:MTH00198 357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 28-192 1.24e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.94  E-value: 1.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154   28 LIWMGLEINMLAIIPILTKKNNprsVEAATKYFLTQATASMLLMMTITINAMYTGQ-WNITNIYD---PLTSTTIIF--- 100
Cdd:TIGR01972 133 VFWEAMLIPMYLLIGVWGGPNR---IYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNlplPFGVQTWLFlaf 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  101 --ALTMKLGMTPFHFWVPEV-----TQGITLTAGMLLltwqKLAPISIM---LQIHP-SMNLDMLLTLALLSTLI--GGW 167
Cdd:TIGR01972 210 fiAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLrfnLPLFPdASLYFAPVLAALGVIAIiyGAL 285

                         170       180
                  ....*....|....*....|....*
gi 529217154  168 GGLNQTQLRKILAYSSIAHMGWMVV 192
Cdd:TIGR01972 286 IALAQTDIKRLIAYSSISHMGFVLL 310
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 50-192 1.05e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 47.00  E-value: 1.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  50 PRSVEAATKYFLTQATASMLLMMTITINAMYTGQW--NITNIYD---PLTSTTIIFALTM-----KLGMTPFHFWVPEV- 118
Cdd:COG1008  157 ERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplPLTAQLLLFLAFFiafavKVPMFPFHTWLPDAh 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 119 ----TQGITLTAGMLL----------------LTWQKLAPISIMLQIhpsmnldmlltlalLSTLIGGWGGLNQTQLRKI 178
Cdd:COG1008  237 veapTAGSVLLAGVLLkmggygllrfalplfpEASAYFAPLLAALGV--------------IGIIYGALVALAQTDLKRL 302

                        170
                 ....*....|....
gi 529217154 179 LAYSSIAHMGWMVV 192
Cdd:COG1008  303 IAYSSVSHMGFVLL 316
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-192 5.16e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 41.73  E-value: 5.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  50 PRSVEAATKYFLTQATASMLLMMTI----TINAMYTGQWNITNIYD---PLTSTTIIF-----ALTMKLGMTPFHFWVPE 117
Cdd:PRK05846 157 KNRIYAATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNlplPPGVQYWLFlaffiAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 118 V-----TQGITLTAGMLLltwqKLAP---ISIMLQIHP--SMNLDMLLTLALLSTLI-GGWGGLNQTQLRKILAYSSIAH 186
Cdd:PRK05846 237 AhvqapTAGSVLLAGILL----KMGAyglLRFSLPLFPdaSHEFAPIIITLGVIAIIyGALVALAQTDIKKLIAYSSISH 312


                 ....*.
gi 529217154 187 MGWMVV 192
Cdd:PRK05846 313 MGFVTL 318
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-315 8.34e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 40.62  E-value: 8.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  98 IIFALTMKLGMTPFHFWVPEVTQGITLTAGMLLLTWQKLAPISIMLQihpsMNLDMLLTLALLSTLIGGWGGLNQTQLRK 177
Cdd:MTH00091  63 QFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQ----FFSKNFFFLLLFGLLICFFQMFLLKSYKN 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 178 ILAYSSIAHMGWMVVVLMYCppltMLNLL-VYLMLTTTMFTMLNvykstttltlstLWNKNPTITLMILISLLSLGGLPP 256
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFS----FFNVFfLFFYYFLLMLFLIP------------KFNNVNKLNFVSWETLLVFMNLPF 202

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 529217154 257 LTGFLPKWMIVQELTKNNNILLATVMVMMALLNLYFYMRLVYSTSLTMFPVSNNTKMKW 315
Cdd:MTH00091 203 SVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-192 3.20e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 39.24  E-value: 3.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  55 AATKYFLTQATASMLLMM----------TITINAMYTGQWNITNIYDPLTSTTIIFALTMKLGMTPFHFWVPE------- 117
Cdd:PRK12561 138 AATKFILYTALASIFILVaglalalsgdTFTFDLAELGAKSYPLALELLLYAGFLIAFGVKLPIFPLHTWLPDahgeasa 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 118 ----VTQGITLTAG----------MLLLTWQKLAPISIMLQIhpsMNLDmlltlallstliggWGGLN---QTQLRKILA 180
Cdd:PRK12561 218 pvsmILAGVLLKMGgyalirfnvqMLPDAHVYFAPALAILGV---VNII--------------YGALNafaQDNVKRRLA 280

                        170
                 ....*....|..
gi 529217154 181 YSSIAHMGWMVV 192
Cdd:PRK12561 281 YSSVSHMGFVLL 292
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-194 4.53e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 38.98  E-value: 4.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  48 NNPRSVEAATKYFLTQATASMLLMMTITINAMYTGQWNIT-------NIYDPLTSTTIIFALTM----KLGMTPFHFWVP 116
Cdd:COG1009  156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSellaaapTILSSPLLTLILLLLLLgafgKSAQFPLHFWLP 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154 117 EVTQGIT-----------LTAGMLLLTwqKLAPIsimLQIHPsmnldmllTLALLSTLIG-------GWGGLNQTQLRKI 178
Cdd:COG1009  236 DAMEGPTpvsallhaatmVKAGVYLLA--RLSPL---FALSP--------VWLTVVAIIGaitalfaALIALAQTDIKRV 302

                        170
                 ....*....|....*.
gi 529217154 179 LAYSSIAHMGWMVVVL 194
Cdd:COG1009  303 LAYSTVSQLGYMFLAL 318
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-190 4.75e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 38.54  E-value: 4.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  33 LEINMLAIIPILTKKNN-PRSVEAATKYFLTQATASMLLMMTItinAMYTGQWNITN-------------IYDPLTSTTI 98
Cdd:PRK08376 150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNmaylavkmsenptVVAKIALALF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  99 IFALTMKLGMTPFHFWVP----EVTQGITltaGMLLLTWQ----KLAPISIML---QIHPSMNLDMLLTLALLSTLIGGW 167
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPdaypAAPSSIS---AMLLVIKQaglyALARVLFSIygpAINLATVGWVIIILGCLTMFVGVA 303

                        170       180
                 ....*....|....*....|...
gi 529217154 168 GGLNQTQLRKILAYSSIAHMGWM 190
Cdd:PRK08376 304 MAVVQKDVKRLLAYHSVSQIGYM 326
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-195 8.49e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 37.98  E-value: 8.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  98 IIFALTMKLGMTPFHFWVPEV-----TQGITLTAGMLL---------LTW-------QKLAPISIMLQIhpsmnldmllt 156
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLklggyglvrLSWpilplgaQNLAPAVIAMGI----------- 304

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 529217154 157 lalLSTLIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLM 195
Cdd:MTH00226 305 ---VGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLV 340
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-210 8.76e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 37.81  E-value: 8.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  17 TTITMISSHWLLIWMGLEINML---AIIPILTKKNNprsVEAATKYFLTQATA------SMLLMMTITINAMYTGQWNIT 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWT 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529217154  88 NIYD--PLTSTTIIFA--------LTMKLGMTPFHFWVPE-----------VTQGITLTAGMLLLTwqKLAPISIMLQIH 146
Cdd:PRK08676 192 ELAAhaSLLSPSVLGAsflfifigFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGIYGIL--RLSALLRQSGAA 269

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 529217154 147 PSMNLDMLLTLALLSTlIGGWGGLNQTQLRKILAYSSIAHMGWMVVVLMYCPPLTMLNLLVYLM 210
Cdd:PRK08676 270 EQFSNVLIGLGIFSIA-VAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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