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Conserved domains on  [gi|745999988|ref|YP_009114784|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Eulemur rubriventer]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-324 2.23e-154

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.97  E-value: 2.23e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320


                 ....
gi 745999988 321 KQTF 324
Cdd:MTH00105 321 KPMT 324
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-324 2.23e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.97  E-value: 2.23e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320


                 ....
gi 745999988 321 KQTF 324
Cdd:MTH00105 321 KPMT 324
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 1.00e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 1.00e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   23 SSHWLLMWIGLEINMLAIIP-ILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWGTTNIYNQ--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   93 --LISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLL-TWQKLAPISI--MLQIYPSMNP---NILLLITTLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirRSLLYLPSSPfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYlMLTVAMFTML----------NINTSTTTLALSNLW 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFH-LLTHGLFSAGlflcagsviyRRVHTRNIRDYGGLA 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 745999988  235 NKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILA 286
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-298 1.08e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 98.26  E-value: 1.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMLTIFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQWGT 86
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGI---SLLYGATGS 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  87 TNIY--------NQLISFTIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIY----P 147
Cdd:COG1007  183 LNLAgiaaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveafP 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 148 SMNP---NILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTVAMFTMLN 220
Cdd:COG1007  263 GLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVIL 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 221 I----NTSTTTLA-LSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLR 295
Cdd:COG1007  343 LlsrkGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                 ...
gi 745999988 296 LIY 298
Cdd:COG1007  423 VVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-297 1.55e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.01  E-value: 1.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988    6 LTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGI---SLIYGFT 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   85 GTTNIYNQLISFT---------------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSM 149
Cdd:TIGR01770 181 GSLNFEDLLLFLSngmlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYI 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  150 -------NPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLML----TVAMFTM 218
Cdd:TIGR01770 261 lfgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  219 L------NINTSTTTLALSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYF 292
Cdd:TIGR01770 341 LsllrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*
gi 745999988  293 YLRLI 297
Cdd:TIGR01770 421 YLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-324 2.23e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 436.97  E-value: 2.23e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320


                 ....
gi 745999988 321 KQTF 324
Cdd:MTH00105 321 KPMT 324
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-324 3.60e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 327.53  E-value: 3.60e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSmNPNILLLITTL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319


                 ....
gi 745999988 321 KQTF 324
Cdd:MTH00135 320 QLTL 323
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-323 2.86e-101

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 302.13  E-value: 2.86e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320


                 ...
gi 745999988 321 KQT 323
Cdd:MTH00112 321 KNT 323
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-317 3.91e-101

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 301.84  E-value: 3.91e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQF 317
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF 317
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-307 9.93e-80

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 247.15  E-value: 9.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPT 307
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-315 4.44e-76

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 237.94  E-value: 4.44e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SGQWGTTNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKW 315
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 8-315 5.09e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 164.67  E-value: 5.09e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWgtt 87
Cdd:MTH00144   8 LFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW--- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  88 niynqLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNP-NILLLITTLSIMVGG 166
Cdd:MTH00144  85 -----FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 167 WGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLwNKTPTMTITILI 246
Cdd:MTH00144 160 IGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIIS 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999988 247 SLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKW 315
Cdd:MTH00144 239 LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-314 1.67e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 160.76  E-value: 1.67e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMY 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SgqwgttNIYNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIypsMNPNILLLITTL 160
Cdd:MTH00160  82 L------MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTM 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 745999988 241 TITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMK 314
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK 306
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-312 4.15e-44

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 154.55  E-value: 4.15e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   6 LTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWG 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  86 TTNiynqliSFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTLSIMVG 165
Cdd:MTH00011  88 NIT------ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 166 GWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTMTITIL 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999988 246 ISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYStSLTMFPTLNNLK 312
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLK 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-317 7.57e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.49  E-value: 7.57e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVtnAMYSGQWGTT 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLYLSL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  88 niynqLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPIsiMLQIYPSMNPNILLLITTLSIMVGGW 167
Cdd:MTH00197  80 -----LSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 168 GGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTVAMFTMLNINTSTTTLALSNLWNKTPTMTITILIS 247
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 248 LLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQF 317
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLL 302
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-298 4.61e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 99.32  E-value: 4.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMLTIFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWGT 86
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  87 TNIYNQLIS----FTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNpnILLLITTLSI 162
Cdd:MTH00199 181 QGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLSI 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 163 MVGGWGGLNQTQLRKIMAYSSIAHMGWMM------------AILMYcpsmtmlnLLIYLMLTVAMFTMLNINTSTTTL-- 228
Cdd:MTH00199 259 IYGAIGALNQTKIKRLLAYSGIGHMGFILfgvaigsfesiqASLIY--------MIIYVIMSICSFSIILSLKLTKGLiv 330

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 229 ALSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIY 298
Cdd:MTH00199 331 EVSGLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 1.00e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 1.00e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   23 SSHWLLMWIGLEINMLAIIP-ILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWGTTNIYNQ--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   93 --LISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLL-TWQKLAPISI--MLQIYPSMNP---NILLLITTLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirRSLLYLPSSPfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYlMLTVAMFTML----------NINTSTTTLALSNLW 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFH-LLTHGLFSAGlflcagsviyRRVHTRNIRDYGGLA 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 745999988  235 NKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILA 286
Cdd:pfam00361 240 KTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-298 1.08e-22

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 98.26  E-value: 1.08e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMLTIFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQWGT 86
Cdd:COG1007  106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGI---SLLYGATGS 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  87 TNIY--------NQLISFTIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIY----P 147
Cdd:COG1007  183 LNLAgiaaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveafP 262

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 148 SMNP---NILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTVAMFTMLN 220
Cdd:COG1007  263 GLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVIL 342

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 221 I----NTSTTTLA-LSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLR 295
Cdd:COG1007  343 LlsrkGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422


                 ...
gi 745999988 296 LIY 298
Cdd:COG1007  423 VVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 4.24e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.48  E-value: 4.24e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  13 IFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQWGTTNIY- 90
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGC---ALLCGTTGGLHLSy 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  91 -----NQLISFT----------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPsmNPNILL 155
Cdd:MTH00196  79 inlvlNSGQSFSsvsvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 156 LITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM------------AILMYcpsmtmlnLLIYLMLTVAMFTM-LNIN 222
Cdd:MTH00196 157 IGGLFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLwgieigsfesiqASLVY--------LFIYIIMSICVFSIiLALN 228

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 745999988 223 TSTTTLA-LSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:MTH00196 229 VYKNLIIeFSGLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-297 1.55e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.01  E-value: 1.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988    6 LTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGI---SLIYGFT 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   85 GTTNIYNQLISFT---------------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSM 149
Cdd:TIGR01770 181 GSLNFEDLLLFLSngmlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYI 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  150 -------NPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLML----TVAMFTM 218
Cdd:TIGR01770 261 lfgfseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  219 L------NINTSTTTLALSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYF 292
Cdd:TIGR01770 341 LsllrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*
gi 745999988  293 YLRLI 297
Cdd:TIGR01770 421 YLRVV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
1-297 1.73e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 92.19  E-value: 1.73e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   1 MKPIILTLIMLTIFmGTMLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAM 79
Cdd:PRK05777 101 GRGEFYLLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGM---SL 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  80 YSGQWGTTNI------------YNQLISFTIIL---ALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQ 144
Cdd:PRK05777 177 LYGATGSLSFagiakaladgsgNSLLLLFGLVFllvGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLR 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 145 IY----PSMNP---NILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTV 213
Cdd:PRK05777 257 LLvvafGGLSEdwqQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTL 336

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 214 AMFTMLNI----NTSTTTLA-LSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALL 288
Cdd:PRK05777 337 GAFGVISLlrrkGGEAESISdFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAI 416


                 ....*....
gi 745999988 289 NLYFYLRLI 297
Cdd:PRK05777 417 GAFYYLRVI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-219 5.67e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.89  E-value: 5.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   9 IMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRST---------EAATKYFLTQATASMLLMFTIVTNAM 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  80 YSGQWG-----------TTNI---YNQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQI 145
Cdd:MTH00198 273 FTGNEGmlgtilsatleTTNIelrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 146 YpsMNPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWmmaILMYCPSMTMLNL-------LIYLMLTVAMFTM 218
Cdd:MTH00198 353 V--ITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGF---ILIGVSAGTYESLqaswtyaVTYLVSALASFTV 427


                 .
gi 745999988 219 L 219
Cdd:MTH00198 428 I 428
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-297 1.01e-10

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 62.76  E-value: 1.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   9 IMLTIFMGTMLTMISSHWLLMWIGLEinMLAIIPILME---KANPRSTEAATKYFLTQATASMLLMFTIvtNAMYSGQWG 85
Cdd:PRK02504 115 ILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGS--SLLYGLSGG 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  86 TTN---IYNQLI---SFTIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLA----PISIMLQIYPS 148
Cdd:PRK02504 191 STQlsaIALALItspSLGLALALVFviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPS 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 149 MNPNILLLITTLSIM---VGGWGGLNQTQLRKIMAYSSIAHMGWMMaILMYCP-----SMTMLNLLIYLMLTVAMFT--- 217
Cdd:PRK02504 271 FDEQWKLLFTALAILsmvLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFAcvi 349

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 218 MLNINTSTTTLA-LSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRL 296
Cdd:PRK02504 350 LFSLRTGTDQISdYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429


                 .
gi 745999988 297 I 297
Cdd:PRK02504 430 I 430
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-301 1.05e-10

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 62.47  E-value: 1.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  10 MLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGqwgTTNI 89
Cdd:COG0651  113 FLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATG---TLNM 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  90 YN-------------QLISFTIILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLLltwqKLAPISIM---LQIYPS 148
Cdd:COG0651  190 ADlaarlaeldpgllLAAFALLLVGFGIKAALFPLHFWLPDAypaapSPVSALLSGLLT----KVGVYAILrvlTLLFGA 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 149 MNPN----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYL---MLTVAMFTML-- 219
Cdd:COG0651  266 DPALflgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhALAKALLFLAag 345

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 220 NINTSTTTLALSNLWNKTPTMTITILISLLSLGGLP---PLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRL 296
Cdd:COG0651  346 AIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAglpPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425


                 ....*
gi 745999988 297 IYSTS 301
Cdd:COG0651  426 FGRAQ 430
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 4-191 3.41e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 51.86  E-value: 3.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988    4 IILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILmekANPRSTEAATKYFLTQATASMLLMFTIVtnAMYSGQ 83
Cdd:TIGR01972 109 YALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVW---GGPNRIYAAMKFFLYTLAGSLLMLLAIL--GLYFLG 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   84 WGTTNI---YNQLISFT--------IILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLLltwqKLAPISIM---LQ 144
Cdd:TIGR01972 184 GGTFDLlelLNLPLPFGvqtwlflaFFIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLrfnLP 259

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 745999988  145 IYP----SMNPnILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:TIGR01972 260 LFPdaslYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 3.50e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 51.62  E-value: 3.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  55 AATKYFLTQATASMLLMFTIVTNAMYSGQWGT--TNIYNQLISFT--------IILALTMKLGMTPFHFWVPEV-----T 119
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTFdiAELAAAPLPLTaqlllflaFFIAFAVKVPMFPFHTWLPDAhveapT 241

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999988 120 QGISLMSGMLLltwqKLAP---ISIMLQIYP---SMNPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMA 192
Cdd:COG1008  242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-191 2.39e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 48.94  E-value: 2.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  54 EAATKYFLTQATASMLLMFTIvtnAMYSGQWGTTNI--------YNQLISFTIILA-----LTMKLGMTPFHFWVPEV-T 119
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMaylavkmsENPTVVAKIALAlfiagLAMKSGAVPVHMWLPDAyP 248

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999988 120 QGISLMSGMLLLTWQK--LAPISIMLQIY-PSMNPN----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08376 249 AAPSSISAMLLVIKQAglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
PRK12650 PRK12650
DUF4040 family protein;
8-192 1.39e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 46.96  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   8 LIMlTIFMGTMLTMI-SSHWLLMWIGLEINMLAIIpILMEKANPRSTEAATKYFLTQATASMLLmftIVTNAMYSGQWGT 86
Cdd:PRK12650 114 LLM-TAFMAAMLLLVlADDVVVLFVAWELVSLASF-FLIARSGSGGEAGSIRTLILTFFGGLTL---LAAVAIAATQTGT 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  87 TNIYNQLIS--------FTIILALTM------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNP- 151
Cdd:PRK12650 189 TSLSGILHSdvwaekpgLTTVVAVLIavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDv 268

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 745999988 152 ---NILLLITTL-SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMA 192
Cdd:PRK12650 269 avwNWLLIIVGMiTALMGAVFAVQKTDLKKLTAYSTVSQLGWIVA 313
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 1.72e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 46.35  E-value: 1.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  55 AATKYFLTQATASMLLMFTIVTNAMYSG-QWGTTNI-----------YNQLISFTIILALTMKLGMTPFHFWVPEV---- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIIYLVVVYYnATGTFDIadllnlplppgVQYWLFLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 119 -TQGISLMSGMLLltwqKLAP---ISIMLQIYPSMNPNILLLITTLSIMV---GGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-191 4.12e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 45.02  E-value: 4.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988   2 KPIILTLIMLTIFMGTMLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYS 81
Cdd:PRK12561  85 KPRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSG 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  82 GQWgTTNIyNQLISFTIILALTM------------KLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQI 145
Cdd:PRK12561 165 DTF-TFDL-AELGAKSYPLALELllyagfliafgvKLPIFPLHTWLPdahgEASAPVSMILAGVLLKMGGYALIRFNVQM 242

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 745999988 146 YPSMN---PNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK12561 243 LPDAHvyfAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVL 291
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 82-286 1.63e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 43.22  E-value: 1.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  82 GQWGTTNIY----NQLISFTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNP-----N 152
Cdd:MTH00207 165 GHWSITNMWqtdmNNYIALSIMIAAMTKSAQMPFSSWLPAAMAAPTPVSALVHSSTLVTAGVFLLIRFYPFLSStywfnP 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 153 ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILmycpSMTMLNLLIYLMLTVAMF---------TMLNINT 223
Cdd:MTH00207 245 ALLLTASLTMLMAGLSAMTECDMKKIIALSTLSQLGVMMASL----GLGMPKLALFHLITHALFkallfvcagSLIHSHH 320

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 745999988 224 STTTL-ALSNLWNKTPTMTITILISLLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILA 286
Cdd:MTH00207 321 HSQDLrTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESSLFYPHNSLMILMIFLA 384
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-323 2.88e-04

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 38.01  E-value: 2.88e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 745999988  291 YFYLRLIYSTSLTMFPTLNNLKMKWQFQQTKQT 323
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNT 33
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
92-206 4.08e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 42.01  E-value: 4.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  92 QLISFT-IILALTMKLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQIYP---SMNPNILLLITTLSIM 163
Cdd:PRK07363 204 QLILLTgLLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAIIGTISVI 283

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 745999988 164 VGGWGGLNQTQLRKIMAYSSIAHMGWmmaILMYCPSMTMLNLL 206
Cdd:PRK07363 284 YGALSAIAQKDIKRMVAYSSIGHMGY---ILVAAAAGTQLSLL 323
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-191 5.81e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.66  E-value: 5.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  17 TMLTMISSHWLLMWIGLEINML---AIIPILMEKANprsTEAATKYFLTQATA------SMLLMFTIVTNAMYSGQWGTT 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWT 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  88 NIYNQ---------LISFTIIL-ALTMKLGMTPFHFWVPEV-TQGISLMSGMLLLTWQKLAPISImLQIYPSMN------ 150
Cdd:PRK08676 192 ELAAHasllspsvlGASFLFIFiGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGI-LRLSALLRqsgaae 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 745999988 151 --PNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08676 271 qfSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
ndhB CHL00049
NADH dehydrogenase subunit 2
 47-297 8.45e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 41.14  E-value: 8.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  47 KANPRSTEAATKYFLTQATASMLLMF----------------TIVTNAMYSGQWGTTNIYNQLISftIILALTMKLGMTP 110
Cdd:CHL00049 155 KKDVRSNEATMKYLLMGGASSSILVYgfswlyglsggeielqEIVNGLINTQMYNSPGISIALIF--ITVGIGFKLSLAP 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 111 FHFWVPEVTQG-----------ISLMSGMLLLTwqklapiSIMLQIYPSMNP---NILLLITTLSIMVGGWGGLNQTQLR 176
Cdd:CHL00049 233 FHQWTPDVYEGsptpvvaflsvTSKVAASALAT-------RIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMK 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 177 KIMAYSSIAHMGWMM-AILMYCPSMTMLNLLIYLML-------TVAMFTMLNINTSTTTLA-LSNLWNKTPTMTITILIS 247
Cdd:CHL00049 306 RMLAYSSIGQIGYVIiGIIVGDSNDGYASMITYMLFyifmnlgTFACIVLFGLRTGTDNIRdYAGLYTKDPFLALSLALC 385

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 745999988 248 LLSLGGLPPLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:CHL00049 386 LLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-190 9.94e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 40.68  E-value: 9.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  10 MLTIFMGTML-TMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFL------TQATASMLLMF----TIVTNA 78
Cdd:PRK06458 113 MYQLFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYanaaTVMGDG 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  79 MYSGQWG-----TTNIYNQLISFTIILALT---MKLGMTPFHFWVPEV-TQGISLMSGML---LLTWQKLAPIS---IML 143
Cdd:PRK06458 193 EMAILWTellkhASLLDPTLMKLAFVFLLIgfgTKVGLFPMHAWLPDAhSEAPSPVSALLsgvLLNVALYAVLRyyiLID 272

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 745999988 144 QIYPSMNPNILLLI-TTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK06458 273 AAIGSDFPGRLLLIfGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-211 1.15e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.81  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 100 LALTMKLGMTPFHFWVPEV-----TQGISLMSGMLLltwqKLAP---ISIMLQIYPSMNPNILLLITTLSIMVGGWGGLN 171
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGygfIRFSWPLLPEASEYFSPLIQTLSLLAIIYGSLT 289

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 745999988 172 ---QTQLRKIMAYSSIAHMGwMMAILMYCPSMTMLNLLIYLML 211
Cdd:MTH00217 290 tcrQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 96-317 2.01e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.47  E-value: 2.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  96 FTIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNILLLITTLSIMVggwgGLNQTQL 175
Cdd:MTH00091  61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 176 RKIMAYSSIAHMGWMMAILMYCPSMTMlnlLIYLMLTVAMFTMLnintstttlalsNLWNKTPTMTITILISLLSLGGLP 255
Cdd:MTH00091 137 KNLLILSSTESFNWLILSFFFSFFNVF---FLFFYYFLLMLFLI------------PKFNNVNKLNFVSWETLLVFMNLP 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 745999988 256 PLTGFLPKWIIVQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQF 317
Cdd:MTH00091 202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 2.34e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 39.48  E-value: 2.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  33 LEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIvtnAMYSGQWGTTNIYN-----------QLISFTIILA 101
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGV---GLLYGVTGTLNMADlagalaenptvVTAFGFVLLA 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 102 LTMKLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNP------NILLLITTLSIMVGGWGGLN 171
Cdd:PRK08375 212 LALKAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGGDFRfalglgWLLAVLALLSMLVGSLAALG 291

                        170       180
                 ....*....|....*....|
gi 745999988 172 QTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08375 292 QDDVKRVLAYSTVSQMGYIL 311
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-219 2.40e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 39.52  E-value: 2.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  98 IILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLL---------LTW-------QKLAPISIMLQIypsmnpnilll 156
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLklggyglvrLSWpilplgaQNLAPAVIAMGI----------- 304

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 745999988 157 ittLSIMVGGWGGLNQTQLRKIMAYSSIAHMGwMMAILMYCPSMTMLNLLIYLMLTVAMFTML 219
Cdd:MTH00226 305 ---VGIVYGSFATCRQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIMLAHGIVSSL 363
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 11-196 4.28e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 39.04  E-value: 4.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  11 LTIFMGTMLTMI-SSHWLLMWIGLEI-NMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGQWGTTN 88
Cdd:PRK12649 117 LLLFMGSMIGMVfSGNTIQLFIFWELtSITSFMLIGYWRHRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIAT 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  89 IYN--QLIS-------FTIILALTM-----KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYP--SMNPN 152
Cdd:PRK12649 197 ILQdsELIEnikghplFLITLILIFigaaaKSAQGPFYIWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPifSGTEA 276

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 745999988 153 ILLLIT---TLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMY 196
Cdd:PRK12649 277 WFILVSgtgMITMVLAGFLAFRQTDIKAILAYSTISQLAYLMTMYGY 323
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
38-206 5.02e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 38.53  E-value: 5.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  38 LAIIPILMEKA---NPRSTEAATKYFLTQATASMLLMFTIVTNAMYSGqwGTTNIYNQLISFT------------IILAL 102
Cdd:PRK06473 138 LELIPLYLLIAiwgGQRRGYAATKFLLYTAISGILILVSFLGLVWLSG--ASSFDYEPLRSHTlplstqllllapILVGF 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 103 TMKLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQIYPSMNPNI---LLLITTLSIMVGGWGGLNQTQL 175
Cdd:PRK06473 216 GIKIPLVPFHTWLPdahvEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEAWVYLapwLATWAVVSVLYGASCAIAQKDM 295

                        170       180       190
                 ....*....|....*....|....*....|.
gi 745999988 176 RKIMAYSSIAHMGWmmaILMYCPSMTMLNLL 206
Cdd:PRK06473 296 KKMVAYSSIGHMGY---ILLAAAAATPLSIL 323
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 11-194 5.39e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 38.59  E-value: 5.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  11 LTIFMGTMLTM-ISSHWLLMWIGLEINMLA---IIPILMEKanPRSTEAATKYFLTQAT------ASMLLMFTIVTNAMY 80
Cdd:COG1009  117 LLLFMAAMLGLvLSDNLLLLFVFWELVGLCsylLIGFWYEK--PSARRAARKAFLVTRVgdlgllLGILLLGAIAGTLNF 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  81 SG--QWGTTNIYNQLISFTIIL----ALTmKLGMTPFHFWVPE-----------------VTQGISLMSgmllltwqKLA 137
Cdd:COG1009  195 SEllAAAPTILSSPLLTLILLLlllgAFG-KSAQFPLHFWLPDamegptpvsallhaatmVKAGVYLLA--------RLS 265

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 138 PISimlqiypSMNPNILLLITT---LSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIL 194
Cdd:COG1009  266 PLF-------ALSPVWLTVVAIigaITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 55-211 8.24e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 37.74  E-value: 8.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988  55 AATKYFLTQATASMLLMFTIVTNAMYSGQWGTTNIYNQLISFTI--------ILALTMKLGMTPFHFWVPEV-----TQG 121
Cdd:MTH00204 164 ASYYFFFYTFAGSVFMLLGIFQLYSITGTTDYQILLNIKLPLSIqkwllvgfFLSLAVKIPQIPFHIWLPQAhveapVAG 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999988 122 ISLMSGMLLltwqKLAP---ISIMLQIYPSMNPNILLLITTLSIMVGGWGGL---NQTQLRKIMAYSSIAHMGwMMAILM 195
Cdd:MTH00204 244 SVILAGILL----KLGGygfLRFSWPLFPAASEYFAPLIVMLSVIAVIYGSLttcRQVDFKRLIAYSSVAHMG-LVPLGL 318

                        170
                 ....*....|....*.
gi 745999988 196 YCPSMTMLNLLIYLML 211
Cdd:MTH00204 319 FTHTIEGLVAAVFLML 334
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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