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Conserved domains on  [gi|1197511542|ref|YP_009368245|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Lepilemur sahamalazensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 3.63e-157

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 444.29  E-value: 3.63e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1197511542 321 NQTQLMSPLIILSTLSLPLAPAFSILH 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 3.63e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 444.29  E-value: 3.63e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1197511542 321 NQTQLMSPLIILSTLSLPLAPAFSILH 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 8.48e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 92.87  E-value: 8.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  18 MLAMISS-HWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNI------INT 89
Cdd:COG1007   115 MMLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLagiaaaLAA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  90 HSQLTPLT------ITIALTMKLGMTPFHFWVPEVTQG-----------ISLMAGMLLLTwqKLAPISIMLQTHPWTnlN 152
Cdd:COG1007   195 GGANSPLLllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpvtaflatAPKIAAFAALL--RLLVEAFPGLAADWQ--L 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 153 ILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPL----TVLNLTIYLALTIVMFTTLNL----NMN 224
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLlsrkGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1197511542 225 TTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIY 298
Cdd:COG1007   351 AEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 1.62e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 84.29  E-value: 1.62e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  23 SSHWLLMWVGLEINMLAIIP-ILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNIINTHSQLTP------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  96 -----LTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLL-TWQKLAPISIMLQTHP-----WTNLNILLLIALLSILV 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLylpssPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYL-------ALTIVMFTTLNLNMNTTT--LTLSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLlthglfsAGLFLCAGSVIYRRVHTRniRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1197511542 236 KTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-297 2.83e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.38  E-value: 2.83e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   8 LIMITIFTGTMLAMISSHWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  87 INTHSQLTPLTITI------------ALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQ---------T 145
Cdd:TIGR01770 186 EDLLLFLSNGMLNIsllllgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRlflyilfgfS 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 146 HPWTNLNILLLIALLSilVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVM----FTTL-- 219
Cdd:TIGR01770 266 EAWQIFLAIIAFLSML--IGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMslgaFGVLsl 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 220 ----NLNMNTTTLTLSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMR 295
Cdd:TIGR01770 344 lrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1197511542 296 LI 297
Cdd:TIGR01770 424 VV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 3.63e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 444.29  E-value: 3.63e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                         330       340
                  ....*....|....*....|....*..
gi 1197511542 321 NQTQLMSPLIILSTLSLPLAPAFSILH 347
Cdd:MTH00105  321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 2.36e-114

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 335.62  E-value: 2.36e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPwTNLNILLLIALL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAP-TNPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|....*.
gi 1197511542 321 NQTQLMSPLIILSTLSLPLAPAFSIL 346
Cdd:MTH00135  320 QLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-341 5.42e-107

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 316.86  E-value: 5.42e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                         330       340
                  ....*....|....*....|.
gi 1197511542 321 NqTQLMSPLIILSTLSLPLAP 341
Cdd:MTH00070  321 T-NNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-341 5.17e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 314.07  E-value: 5.17e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLqTT 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRT-KP 319

                         330       340
                  ....*....|....*....|.
gi 1197511542 321 NQTQLMSPLIILSTLSLPLAP 341
Cdd:MTH00112  320 KKNTLTATLTTLSTLLLPLSP 340
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 3.66e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 240.64  E-value: 3.66e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|....*.
gi 1197511542 321 NQTQLMSpLIILSTLSLPLAPAFSIL 346
Cdd:MTH00200  321 SNLLVGL-LLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-339 1.87e-76

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 238.68  E-value: 1.87e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMY 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 SGQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPT-----FNNTKMKW 315
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQhsislFSWRNSGN 320

                         330       340
                  ....*....|....*....|....
gi 1197511542 316 QLQTTNQTQLMSPLIILSTLSLPL 339
Cdd:MTH00041  321 ITVYGVILSILSSISILGLLLIPL 344
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.16e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 163.84  E-value: 1.16e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   1 MNPITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMy 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  81 sgqwnIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQThpwTNLNILLLIALL 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMI 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 241 TLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKWQLQTT 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                         330
                  ....*....|....*....
gi 1197511542 321 NQTQLMSPLIILSTLSLPL 339
Cdd:MTH00160  313 LILNFLSFISLFGLILSSL 331
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-315 3.58e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 162.36  E-value: 3.58e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   7 LLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNI 86
Cdd:MTH00144    7 LLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  87 InthsqltpLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIA-LLSILVG 165
Cdd:MTH00144   87 M--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVIsVLSALVG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 166 GWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLwNKTPMITLTTM 245
Cdd:MTH00144  159 SIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSII 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 246 IALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLTLFPTFNNTKMKW 315
Cdd:MTH00144  238 SLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-312 1.76e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.76e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   5 TLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQW 84
Cdd:MTH00011    7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  85 NIInthsqlTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALLSILV 164
Cdd:MTH00011   87 KNI------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMITLTT 244
Cdd:MTH00011  161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1197511542 245 MIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYStSLTLFPTFNNTK 312
Cdd:MTH00011  241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLK 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-343 5.57e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 127.48  E-value: 5.57e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   8 LIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYsgqwnii 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSN------- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  88 NTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPIsiMLQTHPWTNLNILLLIALLSILVGGW 167
Cdd:MTH00197   75 LYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLIGGI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 168 GGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTLNLNMNTTTLTLSNLWNKTPMITLTTMIA 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 248 LLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYSTSLtlfptfNNTKMKWQLQTTNQTQLMS 327
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI------LSNWMINFLMKINLLYSGL 306

                         330
                  ....*....|....*.
gi 1197511542 328 PLIILSTLSLPLAPAF 343
Cdd:MTH00197  307 FILLMMMLPLLMIFTM 322
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-298 1.08e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 101.25  E-value: 1.08e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   7 LLIMITIFtGTMLAMISSHWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWN 85
Cdd:MTH00199  101 ILILIVAL-GSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETS 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  86 IINTHSQLT----PLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALLS 161
Cdd:MTH00199  180 IQGINSILTgdvgKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSII 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 162 ilVGGWGGLNQTQLRKILAYSSIAHMG---WMMAILTFCP-PLTVLNLTIYLALTIVMFTTLnLNMNTTT---LTLSNLW 234
Cdd:MTH00199  260 --YGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSII-LSLKLTKgliVEVSGLS 336

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1197511542 235 NKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIY 298
Cdd:MTH00199  337 RKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 8.48e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 92.87  E-value: 8.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  18 MLAMISS-HWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNI------INT 89
Cdd:COG1007   115 MMLMASAnDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLagiaaaLAA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  90 HSQLTPLT------ITIALTMKLGMTPFHFWVPEVTQG-----------ISLMAGMLLLTwqKLAPISIMLQTHPWTnlN 152
Cdd:COG1007   195 GGANSPLLllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpvtaflatAPKIAAFAALL--RLLVEAFPGLAADWQ--L 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 153 ILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPL----TVLNLTIYLALTIVMFTTLNL----NMN 224
Cdd:COG1007   271 LLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLlsrkGGE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1197511542 225 TTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIY 298
Cdd:COG1007   351 AEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-297 5.79e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 86.62  E-value: 5.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  16 GTMLAMISSHWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVL-------------NAMYS 81
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALlcgttgglhlsyiNLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  82 GQWNIINTHSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQTHPwtNLNILLLIALLS 161
Cdd:MTH00196   85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 162 ILVGGWGGLNQTQLRKILAYSSIAHMG---WMMAILTFCPPLTVL-NLTIYLALTIVMFTT-LNLNMNTTTLT-LSNLWN 235
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQASLvYLFIYIIMSICVFSIiLALNVYKNLIIeFSGLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1197511542 236 KTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLI 297
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 1.62e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 84.29  E-value: 1.62e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  23 SSHWLLMWVGLEINMLAIIP-ILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNIINTHSQLTP------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  96 -----LTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLL-TWQKLAPISIMLQTHP-----WTNLNILLLIALLSILV 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLylpssPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYL-------ALTIVMFTTLNLNMNTTT--LTLSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLlthglfsAGLFLCAGSVIYRRVHTRniRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1197511542 236 KTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-297 2.83e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.38  E-value: 2.83e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   8 LIMITIFTGTMLAMISSHWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  87 INTHSQLTPLTITI------------ALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLAPISIMLQ---------T 145
Cdd:TIGR01770 186 EDLLLFLSNGMLNIsllllgivlilvGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRlflyilfgfS 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 146 HPWTNLNILLLIALLSilVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVM----FTTL-- 219
Cdd:TIGR01770 266 EAWQIFLAIIAFLSML--IGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMslgaFGVLsl 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 220 ----NLNMNTTTLTLSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMR 295
Cdd:TIGR01770 344 lrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1197511542 296 LI 297
Cdd:TIGR01770 424 VV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
5-297 4.11e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 79.09  E-value: 4.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   5 TLLLIMitifTGTMLAMISS-HWLLMWVGLEINMLAI-IPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSG 82
Cdd:PRK05777  107 LLVLFA----LLGMMVMVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATG 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  83 QWNI------INTHSQLTPLT------ITIALTMKLGMTPFHFWVPEVTQG-----ISLMAgmlllTWQKLAPISIML-- 143
Cdd:PRK05777  183 SLSFagiakaLADGSGNSLLLlfglvfLLVGLAFKLSAVPFHMWTPDVYEGaptpvTAFLA-----TAPKIAAFAVLLrl 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 144 -----QTHPWTNLNILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTV----LNLTIYLALTIV 214
Cdd:PRK05777  258 lvvafGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsavlFYLLAYLFMTLG 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 215 MFTTLNL----NMNTTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLS 289
Cdd:PRK05777  338 AFGVISLlrrkGGEAESISdFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIG 417


                  ....*...
gi 1197511542 290 LYFYMRLI 297
Cdd:PRK05777  418 AFYYLRVI 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 5-301 9.19e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 68.64  E-value: 9.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   5 TLLLIMITiftGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQW 84
Cdd:COG0651   111 PLFLLLLA---GMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  85 N---IINTHSQLTPLTITIALTM-------KLGMTPFHFWVPE-----------VTQGISLMAGM--LLLTWQKLAPISI 141
Cdd:COG0651   188 NmadLAARLAELDPGLLLAAFALllvgfgiKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADP 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 142 MLQTHPWtnlniLLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTL-- 219
Cdd:COG0651   268 ALFLGTL-----LLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLfl 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 220 ---NLNMNTTTLTLSN---LWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFY 293
Cdd:COG0651   343 aagAIERATGTRDLDKlggLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYF 422


                  ....*...
gi 1197511542 294 MRLIYSTS 301
Cdd:COG0651   423 VRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-267 7.24e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 57.18  E-value: 7.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   3 PITLLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRST---------EAATKYFLTQATASMLLMFT 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  74 IVLNAMYSGQWNIINT--------------HSQLTPLTITIALTMKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLapI 139
Cdd:MTH00198  267 CALYFGFTGNEGMLGTilsatlettnielrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--T 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 140 SIMLQTHPWTNLNILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLN----LTIYLALTIVM 215
Cdd:MTH00198  345 VYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSALAS 424

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1197511542 216 FTTL---------------------NLNMNTTTLTLSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMII 267
Cdd:MTH00198  425 FTVIctleefgtrtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 1.61e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 50.33  E-value: 1.61e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1197511542 291 YFYMRLIYSTSLTLFPTFNNTKMKWQLQTTNQTQLMSPLIILSTLSLPLAP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 5-299 1.49e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 52.79  E-value: 1.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   5 TLLLIMitifTGTMLAMISSHWLL-MWVGLEINMLAIIPIL-MKNYKPRSTEAATKYFLTQATASMLLMFTIvlnAMYSG 82
Cdd:PRK08376  125 TLILLL----ELGMLGMAITGDLFnFFVFLEIMSIASYALVaFRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYG 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  83 QWNIIN-----THSQLTPLTITI--------ALTMKLGMTPFHFWVP----EVTQGISLMagMLLLTWQKLAPI------ 139
Cdd:PRK08376  198 QYGTLNmaylaVKMSENPTVVAKialalfiaGLAMKSGAVPVHMWLPdaypAAPSSISAM--LLVIKQAGLYALarvlfs 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 140 ----SIMLQTHPWtnlnILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM-----AILTFCPPLT--------- 201
Cdd:PRK08376  276 iygpAINLATVGW----VIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglgvGLAALGDPAMasygeiala 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 202 -----VLNLTIYLALT-----IVMFTTLNLNMNTttltLSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIqELS 271
Cdd:PRK08376  352 ggiyhIVNHALYKALLfltagAVIYETGTRNLNE----LGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIY-ESS 426

                         330       340
                  ....*....|....*....|....*...
gi 1197511542 272 KNNNIIMATIMAIMALLSLYFYMRLIYS 299
Cdd:PRK08376  427 ALFNPILGVIAMIGSVLTLASFVKVFHT 454
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-297 6.88e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 47.74  E-value: 6.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   9 IMITIFTGTMLAMISSHWLLMWVGLEinMLAIIPILMKNY---KPRSTEAATKYFLTQATASMLLMFTI-VLNAMYSGQW 84
Cdd:PRK02504  115 ILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTGYmkrDPRSNEAALKYLLIGAASSAIFLYGSsLLYGLSGGST 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  85 N-------IINTHSQLTPLTITIALT---MKLGMTPFHFWVPEVTQGISLMAGMLLLTWQKLA----PISIMLQTHP--- 147
Cdd:PRK02504  193 QlsaialaLITSPSLGLALALVFVIAgiaFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPsfd 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 148 --WtnLNILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCP----PLTVLNLTIYLALTIVMFTTLNL 221
Cdd:PRK02504  273 eqW--KLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTeagyASMVFYLLAYLFMNLGAFACVIL 350

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 222 -NMNTTTLTLSN---LWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLI 297
Cdd:PRK02504  351 fSLRTGTDQISDyagLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVI 430
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 11-300 1.18e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 47.07  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  11 ITIFTGTMLAM-ISSHWLLMWVGLEIN-----MLaiipILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQW 84
Cdd:COG1009   117 LLLFMAAMLGLvLSDNLLLLFVFWELVglcsyLL----IGFWYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  85 NI----INTHSQLTPLTITIALTM-------KLGMTPFHFWVPE-----------------VTQGISLMAgmllltwqKL 136
Cdd:COG1009   193 NFsellAAAPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDamegptpvsallhaatmVKAGVYLLA--------RL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 137 APIsimLQTHPWTnLNILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTI--------- 207
Cdd:COG1009   265 SPL---FALSPVW-LTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGAYVAALFHLLthaffkall 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 208 YLALTIVMFTTLNLNMNtttlTLSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQEL--SKNNNIIMATIMAIM 285
Cdd:COG1009   341 FLGAGSVIHATGTRDIR----KMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLG 416

                         330
                  ....*....|....*
gi 1197511542 286 ALLSLYFYMRLIYST 300
Cdd:COG1009   417 AFLTAFYSFRLFFLV 431
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 6-291 3.29e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 45.32  E-value: 3.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   6 LLLIMITIFTGTMLAMISSHWLLMWVGLEINMLAIIPILMKnykPRSTEAATKYFLTQATASMLLMFTIVLNAMYSG--- 82
Cdd:TIGR01972 111 LLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGG---PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgtf 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  83 QWNIINTHS------QLTPLTITIALTMKLGMTPFHFWVPEV-----TQGISLMAGMLLltwqKLAPISIM---LQTHPW 148
Cdd:TIGR01972 188 DLLELLNLPlpfgvqTWLFLAFFIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLrfnLPLFPD 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 149 TNLNILLLIALL---SILVGGWGGLNQTQLRKILAYSSIAHMGW-MMAILTFCPP------LTVLNLTIYLALTIVMFTT 218
Cdd:TIGR01972 264 ASLYFAPVLAALgviAIIYGALIALAQTDIKRLIAYSSISHMGFvLLGIFSFNELgisgavFQMISHGLITAALFLLVGV 343

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1197511542 219 LNLNMNTTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMA-----TIMAIMALLSLY 291
Cdd:TIGR01972 344 LYERAHTRDIAkYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAFlaalgIVLAAAYMLTLY 422
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 3.75e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 42.33  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  55 AATKYFLTQATASMLLMFTIVLNAMYSGQ--WNIINTHSQLTPLTIT--------IALTMKLGMTPFHFWVP----EVTQ 120
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAKSYPLALElllyagflIAFGVKLPIFPLHTWLPdahgEASA 217

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1197511542 121 GISLMAGMLLLTWQKLAPISIMLQTHPWTNLNILLLIALLSILVGGWGGLN---QTQLRKILAYSSIAHMGWMM 191
Cdd:PRK12561  218 PVSMILAGVLLKMGGYALIRFNVQMLPDAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFVL 291
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 9.87e-04

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 40.83  E-value: 9.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  55 AATKYFLTQATASMLLMFTIVLNAMYSGQW--NIINTHSQLTPLT--------ITIALTMKLGMTPFHFWVPEV-----T 119
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTaqlllflaFFIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 120 QGISLMAGMLL----------------LTWQKLAPISIMLqthpwtnlnillliALLSILVGGWGGLNQTQLRKILAYSS 183
Cdd:COG1008   242 AGSVLLAGVLLkmggygllrfalplfpEASAYFAPLLAAL--------------GVIGIIYGALVALAQTDLKRLIAYSS 307


                  ....*....
gi 1197511542 184 IAHMGWMMA 192
Cdd:COG1008   308 VSHMGFVLL 316
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 172-299 2.21e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 39.57  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 172 QTQLRKILAYSSIAHMGW-MMAIltfcppltvlNLTIYLALTIVMFTTLNLNMNTTTLTLSN-----------------L 233
Cdd:PRK12667  316 QKDVKRLLAYSTISHMGYiFMGI----------GIGTQLGLAAALFHIINHAIAKSLLFLASgvfihaagtrdidelagL 385

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1197511542 234 WNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLIYS 299
Cdd:PRK12667  386 GRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 14-298 5.03e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.82  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  14 FTGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKpRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQWNIINTHSQL 93
Cdd:PRK08668  108 LAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQGL 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  94 TPLT-----------ITIALTMKLGMTPFHFWVPEV------------TQGISLMA--GMLL----LTWQKLAPISIMLQ 144
Cdd:PRK08668  187 INDTstgfalivflfLLAFGVAKAGIFPLHVWAPDAyseapqsfsavlSGQLSKLGayGFLLvlyvLPGTKLFSEFGTYR 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 145 THPWTNLNILLLIALLSIlVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLT-------VLNLTIYLALTIVMFT 217
Cdd:PRK08668  267 GVPLFNYILAWLGNISII-VGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfagglfhVFNHALFKGLFFLIFA 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 218 TLNLNMNTTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRL 296
Cdd:PRK08668  346 AVIYRTGTTKISeMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRP 425


                  ..
gi 1197511542 297 IY 298
Cdd:PRK08668  426 LA 427
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-297 7.65e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 38.06  E-value: 7.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  51 RSTEAATKYFLTQATASMLLMFTIVLNAMYSG--------QWNIINTH------SQLTPLTITIALTMKLGMTPFHFWVP 116
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGFSWLYGLSGgeielqeiVNGLINTQmynspgISIALIFITVGIGFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 117 EVTQG-----------ISLMAGMLLLTwqKLAPISIMLQTHPWtnLNILLLIALLSILVGGWGGLNQTQLRKILAYSSIA 185
Cdd:CHL00049  239 DVYEGsptpvvaflsvTSKVAASALAT--RIFDIPFYFSSNEW--HLLLEILAILSMILGNLIAITQTSMKRMLAYSSIG 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 186 HMGWMM-AILTFCPPLTVLNLTIYLALTIVM-------FTTLNLNMNTTTLT-LSNLWNKTPMITLTTMIALLSLGGLPP 256
Cdd:CHL00049  315 QIGYVIiGIIVGDSNDGYASMITYMLFYIFMnlgtfacIVLFGLRTGTDNIRdYAGLYTKDPFLALSLALCLLSLGGIPP 394

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1197511542 257 LTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLYFYMRLI 297
Cdd:CHL00049  395 LAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 5-298 9.63e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 37.55  E-value: 9.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542   5 TLLLIMITiftGTMLAMISSHWLLMWVGLEINMLAIIPILMKNYKPRSTEAATKYFLTQATASMLLMFTIVLNAMYSGQW 84
Cdd:PRK08375  110 ALFLLLLA---GLLGALLTADLFNLFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTL 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542  85 NIINTHSQLTPLT--------ITIALTMKLGMTPFHFWVPE-----------------VTQGISLMAGMLLLTWQKLAPI 139
Cdd:PRK08375  187 NMADLAGALAENPtvvtafgfVLLALALKAAVFPLHTWLPRaypaappvvtallsglvTKVAVYALIRIYFTVFGGDFRF 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 140 SIMLQThpwtnlnILLLIALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILTFCPPLTVLNLTIYLALTIVMFTTL 219
Cdd:PRK08375  267 ALGLGW-------LLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMKGAL 339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197511542 220 NL-------NMNTTTLT-LSNLWNKTPMITLTTMIALLSLGGLPPLTGFLPKWMIIQELSKNNNIIMATIMAIMALLSLY 291
Cdd:PRK08375  340 FLaagaievTYGTRRLSeLSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALL 419


                  ....*..
gi 1197511542 292 FYMRLIY 298
Cdd:PRK08375  420 YFLRIWY 426
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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