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Conserved domains on  [gi|1236517334|ref|YP_009412791|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microcebus myoxinus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 3.47e-150

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 426.57  E-value: 3.47e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236517334 321 LKKRPLLLSPLIILSTLSLPLSPMFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 3.47e-150

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 426.57  E-value: 3.47e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236517334 321 LKKRPLLLSPLIILSTLSLPLSPMFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 9.74e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.79  E-value: 9.74e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS--VIPILAKNPKpRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCfyVLAGLKRKSR-FSTEAGLKYFILGAFSSGLLLFgisliygftgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  76 FNAMHSGQWTITNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLI---- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 152 ---NLNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMfMVLNMNTNTT 228
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 229 TLTLSNLWSKS-----------PTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMR 297
Cdd:TIGR01770 344 LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1236517334 298 LI 299
Cdd:TIGR01770 424 VV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 2.87e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.99  E-value: 2.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  23 SSHWLLIWIGLEINMLSVIPILAKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNMD---------PN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  93 NMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMVQMFPLIN-----LNTLMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236517334 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 4.46e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 4.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIpILA--KNPKPRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  76 FNAMHSGQWTITNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMVQMFPLI 151
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 152 N---LNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSM----TMLNLFIYLMLTITMFMVLNMN 224
Cdd:COG1007   265 AadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 225 TNTTTLTLSN-----LWSKSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLI 299
Cdd:COG1007   345 SRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424


                  .
gi 1236517334 300 Y 300
Cdd:COG1007   425 K 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 3.47e-150

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 426.57  E-value: 3.47e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236517334 321 LKKRPLLLSPLIILSTLSLPLSPMFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-348 8.56e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 331.38  E-value: 8.56e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLiNLNTLMLIA 160
Cdd:MTH00135   81 TGQWDIQQM--SHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00135  158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00135  238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLP 317

                         330       340
                  ....*....|....*....|....*...
gi 1236517334 321 LKKRPLLLSPLIILSTLSLPLSPMFSTL 348
Cdd:MTH00135  318 STQLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 2.95e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 314.94  E-value: 2.95e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00070   81 TGEWTIMNM--QTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00070  239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK 318

                         330       340
                  ....*....|....*....|...
gi 1236517334 321 LKKrPLLLSPLIILSTLSLPLSP 343
Cdd:MTH00070  319 NKT-NNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-348 3.92e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 314.45  E-value: 3.92e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00112   81 TGQWDITQL--TNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00112  159 ILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00112  239 TLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236517334 321 LKKRPLLLSPLIILSTLsLPLSPMFSTL 348
Cdd:MTH00112  319 PKKNTLTATLTTLSTLL-LPLSPMILTI 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-309 5.01e-77

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 240.22  E-value: 5.01e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTItnMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00041   81 SGSWSI--NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00041  159 ILSVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNP 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPT 309
Cdd:MTH00041  239 ISAFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-348 1.03e-75

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 236.79  E-value: 1.03e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITNMdpNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00200   81 SGQWGISEM--LGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00200  159 LLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00200  239 ILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236517334 321 LKKrPLLLSPLIILSTLSLPLSPMFSTL 348
Cdd:MTH00200  319 SNS-NLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 6.17e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 161.91  E-value: 6.17e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 sgqwtitNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFpliNLNTLMLIA 160
Cdd:MTH00160   81 -------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIII 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00160  151 ILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSK 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFptpNNIKMKWQFQ 320
Cdd:MTH00160  231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNY---NKNKWNLKKK 307

                         330       340
                  ....*....|....*....|....*
gi 1236517334 321 LKKRPLLLSPLIILSTLSLPLSPMF 345
Cdd:MTH00160  308 KNKFSLILNFLSFISLFGLILSSLL 332
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-317 3.49e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 154.66  E-value: 3.49e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWtitnmdpnnmLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINL-NTLMLI 159
Cdd:MTH00144   81 SFSW----------FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 160 ALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMvlNMNTNTTTLTLSNLWSKS 239
Cdd:MTH00144  151 SVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFF--SLWSGDSGSMKDLGSLKP 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236517334 240 PTITTMTLISLLSLGG-LPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00144  229 SYKTGLSIISLLLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-301 1.92e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.92e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   1 MKPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00011    3 STFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  81 SGQWTITnmdpnnmlTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIA 160
Cdd:MTH00011   83 PSLLKNI--------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00011  155 AMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQ 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1236517334 241 TITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYS 301
Cdd:MTH00011  235 TTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-302 7.70e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 127.10  E-value: 7.70e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFtivfnamhsGQWTI 86
Cdd:MTH00197    1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  87 TNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMvqMFPLINLNTLMLIALLSVLA 166
Cdd:MTH00197   72 FSNLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSNLWSKSPTITTMT 246
Cdd:MTH00197  150 GGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFL 229

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1236517334 247 LISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYST 302
Cdd:MTH00197  230 GLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-324 1.30e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 103.94  E-value: 1.30e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   4 PILMIImmtIFTGTMLTMISSHWLLIWIGLEINMLSVIPILA-KNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSG 82
Cdd:MTH00199  100 PILILI---VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  83 QwtiTNMDPNNMLTS-----FTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLntLM 157
Cdd:MTH00199  177 E---TSIQGINSILTgdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNV--VL 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 158 LIALLSVLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMFCP-SMTMLNLFIYLMLTITMFMVLNMNTNTTTLT-- 231
Cdd:MTH00199  252 ICAVLSIIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSIILSLKLTKGLIve 331

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 232 LSNLWSKSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIystSLTLFPTPN 311
Cdd:MTH00199  332 VSGLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVV---QIIYFQADY 408

                         330
                  ....*....|...
gi 1236517334 312 NIkMKWQFQLKKR 324
Cdd:MTH00199  409 SI-LIWQKVLKKE 420
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-299 3.88e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.87  E-value: 3.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  16 GTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKP-RSTEAATKYFLTQATASMLLMF--TIVFNAMHSGQWTITNMDPN 92
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFgcALLCGTTGGLHLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  93 NMLT---------SFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPliNLNTLMLIALLS 163
Cdd:MTH00196   85 SGQSfssvsvpigYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 164 VLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMF-CPSMTMLNLFIYLMLTITMFMVLNMNTNTTTLTLSN--LWS 237
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFeSIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFsgLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236517334 238 KSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLI 299
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 9.74e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.79  E-value: 9.74e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS--VIPILAKNPKpRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCfyVLAGLKRKSR-FSTEAGLKYFILGAFSSGLLLFgisliygftgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  76 FNAMHSGQWTITNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLI---- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 152 ---NLNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLMLTITMfMVLNMNTNTT 228
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 229 TLTLSNLWSKS-----------PTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMR 297
Cdd:TIGR01770 344 LRSYKDEWIEYisdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1236517334 298 LI 299
Cdd:TIGR01770 424 VV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 2.87e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.99  E-value: 2.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  23 SSHWLLIWIGLEINMLSVIPILAKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNMD---------PN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  93 NMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMVQMFPLIN-----LNTLMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236517334 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 4.46e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 4.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIpILA--KNPKPRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  76 FNAMHSGQWTITNMDPNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIS----IMVQMFPLI 151
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 152 N---LNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSM----TMLNLFIYLMLTITMFMVLNMN 224
Cdd:COG1007   265 AadwQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 225 TNTTTLTLSN-----LWSKSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLI 299
Cdd:COG1007   345 SRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424


                  .
gi 1236517334 300 Y 300
Cdd:COG1007   425 K 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-299 6.44e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 78.32  E-value: 6.44e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   4 PILMIIMmtifTGTMLTMISS-HWLLIWIGLEINMLS--VIPILAKNpKPRSTEAATKYFLTQATASMLLMF-------- 72
Cdd:PRK05777  106 YLLVLFA----LLGMMVMVSAnDLLTLFLGLELLSLPlyALAALRRD-RRRSLEAAIKYFVLGALASGFLLYgmsllyga 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  73 --TIVFNAMHSgqwTITNMDPNNMLTSFT---MIIALTMKLGMAPFHFWVPEVTQG-----VSLMTG-------MLLLTW 135
Cdd:PRK05777  181 tgSLSFAGIAK---ALADGSGNSLLLLFGlvfLLVGLAFKLSAVPFHMWTPDVYEGaptpvTAFLATapkiaafAVLLRL 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 136 QKLAPISIMVQMFPLinlntLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM-AILMFCPSM---TMLNLFIYL 211
Cdd:PRK05777  258 LVVAFGGLSEDWQQV-----LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLvGLAAGTAEGysaVLFYLLAYL 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 212 MLTITMF-MVLNMNTNTTTLTLSNLWS----KSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAI 286
Cdd:PRK05777  333 FMTLGAFgVISLLRRKGGEAESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVL 412

                         330
                  ....*....|...
gi 1236517334 287 MALLNLYFYMRLI 299
Cdd:PRK05777  413 NSAIGAFYYLRVI 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-303 4.24e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 69.79  E-value: 4.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  15 TGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNM----- 89
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLaarla 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  90 --DPNNMLTSFTMI-IALTMKLGMAPFHFWVPEV----TQGVS-LMTGMLLltwqKLAPISIM---VQMFPLINLNT--- 155
Cdd:COG0651   198 elDPGLLLAAFALLlVGFGIKAALFPLHFWLPDAypaaPSPVSaLLSGLLT----KVGVYAILrvlTLLFGADPALFlgt 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 156 -LMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFIYL----MLTITMFM----VLNMNTN 226
Cdd:COG0651   274 lLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLaagaIERATGT 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1236517334 227 TTTLTLSNLWSKSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTS 303
Cdd:COG0651   354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-193 1.08e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 66.04  E-value: 1.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  16 GTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRST---------EAATKYFLTQATASMLLMFTIVF---------- 76
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  77 -NAMHSGQWTITNMDPNNMLTSFTMI-IALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMfpLINLN 154
Cdd:MTH00198  280 lGTILSATLETTNIELRQGSLGYLFItVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VITSK 357

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1236517334 155 TLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 2.45e-09

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 58.50  E-value: 2.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   2 KPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK12561   85 KPRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSG 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  82 GQWT--ITNMDPNNMLTSFTM------IIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMFP 149
Cdd:PRK12561  165 DTFTfdLAELGAKSYPLALELllyagfLIAFGVKLPIFPLHTWLPdahgEASAPVSMILAGVLLKMGGYALIRFNVQMLP 244

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236517334 150 LINLNTLMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK12561  245 DAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFVL 291
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-194 4.03e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 57.78  E-value: 4.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  55 AATKYFLTQATASMLLMFTIVFNAMHSGQWTI-------TNMDPN-NMLTSFTMIIALTMKLGMAPFHFWVPEV-----T 121
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTFdiaelaaAPLPLTaQLLLFLAFFIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1236517334 122 QGVSLMTGMLLltwqKLAP---ISIMVQMFP---LINLNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMA 194
Cdd:COG1008   242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 6-193 7.55e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 56.87  E-value: 7.55e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   6 LMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNA-MHSGQW 84
Cdd:TIGR01972 108 FYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILGLYfLGGGTF 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  85 TITNMDPNNMLTSFTMI------IALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIMV---QMFP- 149
Cdd:TIGR01972 188 DLLELLNLPLPFGVQTWlflaffIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLRfnlPLFPd 263

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1236517334 150 --LINLNTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:TIGR01972 264 asLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-193 1.60e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 52.90  E-value: 1.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  55 AATKYFL-TQAT-----ASMLLMFTIVFNAMHS---GQWTITNMDPN-NMLTSFTMIIALTMKLGMAPFHFWVPEV---- 120
Cdd:PRK05846  162 AATKFFLyTLLGsllmlVAIIYLVVVYYNATGTfdiADLLNLPLPPGvQYWLFLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 121 -TQGVSLMTGMLLltwqKLAP---ISIMVQMFPLINLNTLMLIALLSVLA---GGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK05846  242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 7.92e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 50.65  E-value: 7.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  33 LEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQwtiTNM---------DPNNMLTSFTMIIA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGT---LNMadlagalaeNPTVVTAFGFVLLA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 104 LTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMFP------LINLNTLMLIALLSVLAGGWGGLN 173
Cdd:PRK08375  212 LALKAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGgdfrfaLGLGWLLAVLALLSMLVGSLAALG 291

                         170       180
                  ....*....|....*....|
gi 1236517334 174 QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08375  292 QDDVKRVLAYSTVSQMGYIL 311
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
7-265 9.02e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 50.43  E-value: 9.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEinMLSVIPILAK---NPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQ 83
Cdd:PRK02504  113 AAILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  84 WTITNMDPNNMLTSFTMIIALTM---------KLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLA----PISIMVQMFPL 150
Cdd:PRK02504  191 STQLSAIALALITSPSLGLALALvfviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPS 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 151 INLN---TLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMaILMFCP-----SMTMLNLFIYLMLTITMFMVLN 222
Cdd:PRK02504  271 FDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFACVI 349

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1236517334 223 MNTNTTTLTLSNLWS----KSPTITTMTLISLLSLGGLPPLTGFLPK 265
Cdd:PRK02504  350 LFSLRTGTDQISDYAglyqKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 2.04e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 49.33  E-value: 2.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  33 LEINMLSVIPILA-KNPKPRSTEAATKYFLTQATASMLLMFTIvfnAMHSGQWTITNMDPNNMLTSFTM----------- 100
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSENPtvvakialalf 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 101 IIALTMKLGMAPFHFWVPEV-TQGVSLMTGMLLLTWQK--LAPISIMVQMF-PLINLNTL----MLIALLSVLAGGWGGL 172
Cdd:PRK08376  227 IAGLAMKSGAVPVHMWLPDAyPAAPSSISAMLLVIKQAglYALARVLFSIYgPAINLATVgwviIILGCLTMFVGVAMAV 306

                         170       180
                  ....*....|....*....|.
gi 1236517334 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08376  307 VQKDVKRLLAYHSVSQIGYML 327
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 293-343 4.23e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 43.40  E-value: 4.23e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1236517334 293 YFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKRPLLLSPLIILSTLSLPLSP 343
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-319 8.14e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 43.71  E-value: 8.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  98 FTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMVQMFPLINLNTLMLIALLSVLAggwgGLNQTQL 177
Cdd:MTH00091   61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 178 RKILAYSSIAHMGWMMAILMFCPSMTMlnlFIYLMLTITMFMVlnmntntttltlSNLWSKSPTITTMTLISLLSLGGLP 257
Cdd:MTH00091  137 KNLLILSSTESFNWLILSFFFSFFNVF---FLFFYYFLLMLFL------------IPKFNNVNKLNFVSWETLLVFMNLP 201

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236517334 258 PLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQF 319
Cdd:MTH00091  202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-193 1.09e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 43.92  E-value: 1.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 100 MIIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMFP---LINLNTLMLIALLSVLAGGWGGL 172
Cdd:PRK06473  211 ILVGFGIKIPLVPFHTWLPdahvEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPeawVYLAPWLATWAVVSVLYGASCAI 290

                          90       100
                  ....*....|....*....|.
gi 1236517334 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK06473  291 AQKDMKKMVAYSSIGHMGYIL 311
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-192 1.29e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 43.77  E-value: 1.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  10 MMTIFTGTM-LTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFL------TQATASMLLMFTIVFNAMHSG 82
Cdd:PRK06458  113 MYQLFLFTMlLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  83 Q----WTITN-----MDPNNMLTSFTMI-IALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMF 148
Cdd:PRK06458  193 EmailWTELLkhaslLDPTLMKLAFVFLlIGFGTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRYYILID 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1236517334 149 PLIN---LNTLMLI-ALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWM 192
Cdd:PRK06458  273 AAIGsdfPGRLLLIfGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-193 4.09e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.05  E-value: 4.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  17 TMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATA------SMLLMFTIVFNAMHSG--QWT--- 85
Cdd:PRK08676  115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTela 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  86 --ITNMDPNNMLTSFT-MIIALTMKLGMAPFHFWVPEV-TQGVSLMTGMLLLTWQKLAPISImVQMFPLIN--------L 153
Cdd:PRK08676  195 ahASLLSPSVLGASFLfIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGI-LRLSALLRqsgaaeqfS 273

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1236517334 154 NTLMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08676  274 NVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 102-213 4.78e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 41.96  E-value: 4.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 102 IALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIMVQMFPLINLNTLM---LIALLSVLAGGWGGLN 173
Cdd:MTH00217  214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGYGFIRFSWPLLPEASEYfspLIQTLSLLAIIYGSLT 289

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1236517334 174 ---QTQLRKILAYSSIAHMGwMMAILMFCPSMTMLNLFIYLML 213
Cdd:MTH00217  290 tcrQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 8.36e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 41.23  E-value: 8.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334   2 KPPILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK02546  113 KPKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMAFYG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  82 GQWT--ITNMDPNNMLTSFTM------IIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMFP 149
Cdd:PRK02546  193 DTPTfdMTALAAKDFGLGFQLlcyaglLIAYGVKLPIVPLHTWLPdahgEATAPVHMLLAGILLKMGGYALLRMNAGMLP 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236517334 150 LINLNTLMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK02546  273 DAHAQFAPLLIVLGVVNIIYAALTsfaQRNLKRKIAYSSISHMGFVL 319
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
100-193 9.67e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 40.85  E-value: 9.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 100 MIIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMVQMFP---LINLNTLMLIALLSVLAGGWGGL 172
Cdd:PRK07363  211 LLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAIIGTISVIYGALSAI 290

                          90       100
                  ....*....|....*....|.
gi 1236517334 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK07363  291 AQKDIKRMVAYSSIGHMGYIL 311
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 102-213 1.09e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.82  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 102 IALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIMVQMFPLINLNTLM---LIALLSVLAGGWGGL- 172
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLRFSWPLFPAASEYfapLIVMLSVIAVIYGSLt 292

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1236517334 173 --NQTQLRKILAYSSIAHMGwMMAILMFCPSMTMLNLFIYLML 213
Cdd:MTH00204  293 tcRQVDFKRLIAYSSVAHMG-LVPLGLFTHTIEGLVAAVFLML 334
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 17-301 2.11e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 39.80  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  17 TMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFT---IVFNAMHSGQWTITNM-DPN 92
Cdd:PRK06589  129 GVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPaviLIYTKTGNLDFVSGGLfSKN 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  93 NMLTSFTMIIALTMKLGMAPFHFWVPEV----TQGVSLMTGMLLLTWQKLAPISIMVQMFPLINL-------NTLMLIAL 161
Cdd:PRK06589  209 QSIILLLMFIYGIAKTAIFPVHSWLPAAmvahYPVSALLHAVIVVKTGLFCIYKILLYIFGLSYLqrifaefNWLIFIPI 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 162 LSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM--AILMFCPSM--TMLNLFIYLMLTITMFMVLNMNTNTT----TLTLS 233
Cdd:PRK06589  289 VSIFYSSLKALKTDNIKKILAYSTISQLSLALlsAFILTPKALgaAILHLVSHSFAKICLFYSMGSIYSLKkedqVDKLH 368

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236517334 234 NLWSKSPTITTMTLISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIM----ALLNLYFYMRLIYS 301
Cdd:PRK06589  369 GTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALYLLKILSS 440
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 100-213 2.99e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 39.52  E-value: 2.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 100 MIIALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIMVQMFPLINLNT------LMLIALLSVLAGG 168
Cdd:MTH00226  236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPILPLGAqnlapaVIAMGIVGIVYGS 311

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1236517334 169 WGGLNQTQLRKILAYSSIAHMGwMMAILMFCPSMTMLNLFIYLML 213
Cdd:MTH00226  312 FATCRQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIML 355
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-301 5.51e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 38.41  E-value: 5.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334  49 KPRSTEAATKYFLTQATASMLLMFTIVF--------------NAMHSGQWTITNMDPNNMLTSFTMIIAL-----TMKLG 109
Cdd:PRK12667  159 RGDAVEAAIKYALIGAVGTTLYFLALAFlyatfgtlnmadlsAKIRGLSFPLTGGLAGNPPLALGVALALalwafTIKAA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 110 MAPFHFWVPEV----TQGVSLMTGMLLLTWQKLAPISIMVQMF-------PLIN--LNTLMLIALLSVLAGGWGGLNQTQ 176
Cdd:PRK12667  239 IFPNHFWLPDAhpaaPSPVSAMLSGLVVNVGAYAIIRFLYTIFgispsliDFRAalSPILIILGAVSAIIGALMMVVQKD 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236517334 177 LRKILAYSSIAHMGW-MMAILMfcPSMTMLNLFIYL---------MLTITMFMVLNMNTNTTTLTLSNLWSKSPTITTMT 246
Cdd:PRK12667  319 VKRLLAYSTISHMGYiFMGIGI--GTQLGLAAALFHiinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAF 396

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1236517334 247 LISLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMAIMALLNLYFYMRLIYS 301
Cdd:PRK12667  397 LIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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