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Conserved domains on  [gi|1236513031|ref|YP_009412804|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microcebus griseorufus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 6.04e-145

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 413.09  E-value: 6.04e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236513031 321 LKKQSLLLSPLIILSTLTLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 6.04e-145

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 413.09  E-value: 6.04e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236513031 321 LKKQSLLLSPLIILSTLTLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-299 1.79e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.79e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   6 LVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG-- 82
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 -------QWTTINIDPNNMLMSLT-MIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLS------ 148
Cdd:TIGR01770 184 nfedlllFLSNGMLNISLLLLGIVlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 149 -SSINPTTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLML-TVTMFTMLNMNTN 226
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 227 TTTLTLSNLWSKS---------PMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMR 297
Cdd:TIGR01770 344 LRSYKDEWIEYISdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1236513031 298 LI 299
Cdd:TIGR01770 424 VV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-300 2.31e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   4 PILVIIMTTiftGTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG 82
Cdd:COG1007   105 YALLLFATL---GMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 qwtTINID------PNNMLMSLTMIIALTM-------KLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSS 149
Cdd:COG1007   182 ---SLNLAgiaaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLV 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 150 SINP-------TTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTM----F 218
Cdd:COG1007   259 EAFPglaadwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMnlgaF 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 219 TMLNMNTNTTTLTLSN-----LWSKSPMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLY 293
Cdd:COG1007   339 AVILLLSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAY 418


                  ....*..
gi 1236513031 294 FYMRLIY 300
Cdd:COG1007   419 YYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 3.81e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.91  E-value: 3.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  23 SSHWLLIWIGLEINMLSIIP-ILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQWTTINID---------PN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  93 NMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLL-TWQKLAPISIM-----MQLSSSINPTTLMLIALMSVLI 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236513031 167 GGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 6.04e-145

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 413.09  E-value: 6.04e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1236513031 321 LKKQSLLLSPLIILSTLTLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-348 3.55e-107

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 317.13  E-value: 3.55e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSiNPTTLMLIA 160
Cdd:MTH00135   81 TGQWDIQQM--SHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00135  158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00135  238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLP 317

                         330       340
                  ....*....|....*....|....*...
gi 1236513031 321 LKKQSLLLSPLIILSTLTLPLSPVFSTL 348
Cdd:MTH00135  318 STQLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 4.60e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 306.85  E-value: 4.60e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00070   81 TGEWTIMNM--QTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00070  239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK 318

                         330       340
                  ....*....|....*....|...
gi 1236513031 321 LKKqSLLLSPLIILSTLTLPLSP 343
Cdd:MTH00070  319 NKT-NNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-348 2.19e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 305.21  E-value: 2.19e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTINIdpNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00112   81 TGQWDITQL--TNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00112  159 ILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00112  239 TLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236513031 321 lKKQSLLLSPLIILSTLTLPLSPVFSTL 348
Cdd:MTH00112  319 -PKKNTLTATLTTLSTLLLPLSPMILTI 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 5-309 2.28e-74

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 233.67  E-value: 2.28e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   5 ILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQW 84
Cdd:MTH00041    5 VLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  85 TTIniDPNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIALMSV 164
Cdd:MTH00041   85 SIN--GPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSV 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 165 LIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSPMITM 244
Cdd:MTH00041  163 LVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAF 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1236513031 245 TILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPT 309
Cdd:MTH00041  243 LFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-348 3.39e-72

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 227.93  E-value: 3.39e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTIniDPNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00200   81 SGQWGIS--EMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00200  159 LLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQFQ 320
Cdd:MTH00200  239 ILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1236513031 321 LKKqSLLLSPLIILSTLTLPLSPVFSTL 348
Cdd:MTH00200  319 SNS-NLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-316 2.37e-45

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 157.68  E-value: 2.37e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMy 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 sgqwttiNIDPNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPisiMMQLSSSINPTTLMLIA 160
Cdd:MTH00160   81 -------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAP---LILLSYLINNNFIIIII 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00160  151 ILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSK 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMK 316
Cdd:MTH00160  231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK 306
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-317 4.64e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 154.27  E-value: 4.64e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWttinidpnnmLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINP-TTLMLI 159
Cdd:MTH00144   81 SFSW----------FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVI 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 160 ALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLwSKS 239
Cdd:MTH00144  151 SVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPS 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1236513031 240 PMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00144  230 YKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-301 6.21e-43

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 151.47  E-value: 6.21e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   1 MKPPILVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMY 80
Cdd:MTH00011    3 STFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  81 SGQWTTInidpnnmlMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTTLMLIA 160
Cdd:MTH00011   83 PSLLKNI--------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 161 LMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSP 240
Cdd:MTH00011  155 AMSALAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQ 234

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1236513031 241 MITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYS 301
Cdd:MTH00011  235 TTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-302 6.46e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 127.48  E-value: 6.46e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  12 TIFTGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFnivfnamysGQWTTINIDP 91
Cdd:MTH00197    6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLSFSNLY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  92 NNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSsiNPTTLMLIALMSVLIGGWGG 171
Cdd:MTH00197   77 LSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGIGG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 172 LNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTMFTMLNMNTNTTTLTLSNLWSKSPMITMTILISLL 251
Cdd:MTH00197  155 MNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFL 234

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1236513031 252 SLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYST 302
Cdd:MTH00197  235 SLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-324 2.06e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 97.39  E-value: 2.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   4 PILVIIMTTiftGTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG 82
Cdd:MTH00199  100 PILILIVAL---GSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 QwttINIDPNNMLMS-----LTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINptTLM 157
Cdd:MTH00199  177 E---TSIQGINSILTgdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVL 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 158 LIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMM--VILTFYPSL--TVLNLLVYLMLTVTMFTMLNMNTNTTTLT-- 231
Cdd:MTH00199  252 ICAVLSIIYGAIGALNQTKIKRLLAYSGIGHMGFILfgVAIGSFESIqaSLIYMIIYVIMSICSFSIILSLKLTKGLIve 331

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 232 LSNLWSKSPMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIystSLTLFPTPN 311
Cdd:MTH00199  332 VSGLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVV---QIIYFQADY 408

                         330
                  ....*....|...
gi 1236513031 312 NIkMKWQFQLKKQ 324
Cdd:MTH00199  409 SI-LIWQKVLKKE 420
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-299 1.53e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 91.25  E-value: 1.53e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  16 GTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG--QWTTINIDPN 92
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGglHLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  93 NMLM---------SLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINptTLMLIALMS 163
Cdd:MTH00196   85 SGQSfssvsvpigYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 164 VLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTM--FTMLNMNTNTTTLTLSNLWS---- 237
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFIYIIMsiCVFSIILALNVYKNLIIEFSglsr 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1236513031 238 KSPMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLI 299
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-299 1.79e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.79e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   6 LVIIMTTIFTGTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG-- 82
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGsl 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 -------QWTTINIDPNNMLMSLT-MIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLS------ 148
Cdd:TIGR01770 184 nfedlllFLSNGMLNISLLLLGIVlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 149 -SSINPTTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLML-TVTMFTMLNMNTN 226
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyALMSLGAFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 227 TTTLTLSNLWSKS---------PMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMR 297
Cdd:TIGR01770 344 LRSYKDEWIEYISdfaglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 1236513031 298 LI 299
Cdd:TIGR01770 424 VV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-300 2.31e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.31e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   4 PILVIIMTTiftGTMLTMISSHWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG 82
Cdd:COG1007   105 YALLLFATL---GMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 qwtTINID------PNNMLMSLTMIIALTM-------KLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSS 149
Cdd:COG1007   182 ---SLNLAgiaaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLV 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 150 SINP-------TTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTM----F 218
Cdd:COG1007   259 EAFPglaadwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMnlgaF 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 219 TMLNMNTNTTTLTLSN-----LWSKSPMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLY 293
Cdd:COG1007   339 AVILLLSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAY 418


                  ....*..
gi 1236513031 294 FYMRLIY 300
Cdd:COG1007   419 YYLRVVK 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-213 3.81e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 88.91  E-value: 3.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  23 SSHWLLIWIGLEINMLSIIP-ILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQWTTINID---------PN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  93 NMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLL-TWQKLAPISIM-----MQLSSSINPTTLMLIALMSVLI 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1236513031 167 GGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLML 213
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLT 207
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-217 1.51e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 80.25  E-value: 1.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   4 PILVIIMTtiftGTMLTMISS-HWLLIWIGLEINMLSI-IPILMKSPKPRSTEAATKYFLTQATASMLLMFNIvfnAMYS 81
Cdd:PRK05777  106 YLLVLFAL----LGMMVMVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGM---SLLY 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  82 GQWTTINIDP------NNMLMSLTMIIALTM-------KLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLS 148
Cdd:PRK05777  179 GATGSLSFAGiakalaDGSGNSLLLLFGLVFllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLL 258

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236513031 149 SSINPTT-------LMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLMLTVTM 217
Cdd:PRK05777  259 VVAFGGLsedwqqvLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFM 334
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-194 1.37e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 68.73  E-value: 1.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  16 GTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRST---------EAATKYFLTQATASMLLMFNIVF---------- 76
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  77 -NAMYSGQWTTINID-PNNMLMSLTMIIALTMKLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSssINPT 154
Cdd:MTH00198  280 lGTILSATLETTNIElRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV--ITSK 357

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1236513031 155 TLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMV 194
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-218 4.43e-11

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 63.92  E-value: 4.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031   9 IMTTIFTGTMLTMISSHWLLIWIGLEinMLSIIPILMK---SPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQWT 85
Cdd:PRK02504  115 ILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGGST 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  86 TINIDPNNMLMSLTMIIALTM---------KLGMTPFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINP--- 153
Cdd:PRK02504  193 QLSAIALALITSPSLGLALALvfviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfd 272

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1236513031 154 ----TTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTF-----YPSLtVLNLLVYLMLTVTMF 218
Cdd:PRK02504  273 eqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAgteagYASM-VFYLLAYLFMNLGAF 345
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-194 8.40e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 56.63  E-value: 8.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  55 AATKYFLTQATASMLLMFNIVFNAMYSGQWTT-------INIDPN-NMLMSLTMIIALTMKLGMTPFHFWVPEV-----T 121
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTFdiaelaaAPLPLTaQLLLFLAFFIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 122 QGISLMTGMLL----------------LTWQKLAPIsimmqlsssinpttLMLIALMSVLIGGWGGLNQTQLRKILAYSS 185
Cdd:COG1008   242 AGSVLLAGVLLkmggygllrfalplfpEASAYFAPL--------------LAALGVIGIIYGALVALAQTDLKRLIAYSS 307


                  ....*....
gi 1236513031 186 IAHMGWMMV 194
Cdd:COG1008   308 VSHMGFVLL 316
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-303 3.41e-08

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 54.77  E-value: 3.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  15 TGTMLTMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQWT-------TI 87
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNmadlaarLA 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  88 NIDPNNMLMSLTMI-IALTMKLGMTPFHFWVPE-----------VTQGISLMTGM--LLLTWQKLAPISIMMQLSssinp 153
Cdd:COG0651   198 ELDPGLLLAAFALLlVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLG----- 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 154 TTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYL---MLTVTMF-----TMLNMNT 225
Cdd:COG0651   273 TLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhALAKALLflaagAIERATG 352

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1236513031 226 NTTTLTLSNLWSKSPMITMTILISLLSLGGLPPLTGFLPKWVIIQELTKNNNITMATMMTIMALLNLYFYMRLIYSTS 303
Cdd:COG0651   353 TRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 49-194 8.47e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 53.40  E-value: 8.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  49 KPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGQWTTINIDPNN-------MLMSLTMIIALTMKLGMTPFHFWVPEV- 120
Cdd:TIGR01972 151 GPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGTFDLLELLNLplpfgvqTWLFLAFFIAFAVKVPLFPLHTWLPDAh 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 121 ----TQGISLMTGMLLltwqKLAPISIM---MQL---SSSINPTTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMG 190
Cdd:TIGR01972 231 veapTAGSVILAGVLL----KMGTYGFLrfnLPLfpdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMG 306


                  ....
gi 1236513031 191 WMMV 194
Cdd:TIGR01972 307 FVLL 310
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-193 6.75e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 50.87  E-value: 6.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  49 KPRSTEAATKYFLTQATASMLLMFNIvfnAMYSGQWTTINIDPNNMLMSLTM-----------IIALTMKLGMTPFHFWV 117
Cdd:PRK08376  167 TWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSENPtvvakialalfIAGLAMKSGAVPVHMWL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 118 PEV-TQGISLMTGMLLLTwqKLAPISIMMQLSSSI-----NPTTL----MLIALMSVLIGGWGGLNQTQLRKILAYSSIA 187
Cdd:PRK08376  244 PDAyPAAPSSISAMLLVI--KQAGLYALARVLFSIygpaiNLATVgwviIILGCLTMFVGVAMAVVQKDVKRLLAYHSVS 321


                  ....*.
gi 1236513031 188 HMGWMM 193
Cdd:PRK08376  322 QIGYML 327
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-194 9.08e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 50.31  E-value: 9.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  10 MTTIFTGTML-TMISSHWLLIWIGLEINMLSIIPILMKSPKPRSTEAATKYFL------TQATASMLLMFNIVFNAMYSG 82
Cdd:PRK06458  113 MYQLFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  83 Q----WTTINIDP---NNMLMSLTMIIALT---MKLGMTPFHFWVP----EVTQGISLMTGMLLLTWQKLAPISIMMQLS 148
Cdd:PRK06458  193 EmailWTELLKHAsllDPTLMKLAFVFLLIgfgTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRYYILID 272

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1236513031 149 SSIN---PTTLMLI-ALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMV 194
Cdd:PRK06458  273 AAIGsdfPGRLLLIfGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-194 3.45e-06

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 48.49  E-value: 3.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  55 AATKYFLTQATASMLLMFNIVFNAMYSGQwTTINIDPNNM---------LMSLTMIIALTMKLGMTPFHFWVP----EVT 121
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDT-FTFDLAELGAksyplalelLLYAGFLIAFGVKLPIFPLHTWLPdahgEAS 216

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236513031 122 QGISLMTGMLLLTWQKLAPISIMMQLSSSINPT---TLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMV 194
Cdd:PRK12561  217 APVSMILAGVLLKMGGYALIRFNVQMLPDAHVYfapALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLL 292
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 293-343 6.09e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 43.02  E-value: 6.09e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1236513031 293 YFYMRLIYSTSLTLFPTPNNIKMKWQFQLKKQSLLLSPLIILSTLTLPLSP 343
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-212 6.94e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.57  E-value: 6.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  33 LEINMLSIIPILMKSPKPRSTEAATKYFLTQATASMLLMFNIVFNAMYSGqwtTINI---------DPNNMLMSLTMIIA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTG---TLNMadlagalaeNPTVVTAFGFVLLA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 104 LTMKLGMTPFHFWVPEV-TQGISLMTGMLLLTWQKlAPISIMMQLSSSINPTT----------LMLIALMSVLIGGWGGL 172
Cdd:PRK08375  212 LALKAAVFPLHTWLPRAyPAAPPVVTALLSGLVTK-VAVYALIRIYFTVFGGDfrfalglgwlLAVLALLSMLVGSLAAL 290

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1236513031 173 NQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLM 212
Cdd:PRK08375  291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLL 330
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-194 6.20e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.81  E-value: 6.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  55 AATKYFL-TQAT-----ASMLLMFNIVFNAMYSGQWTTI---NIDPN-NMLMSLTMIIALTMKLGMTPFHFWVPEV---- 120
Cdd:PRK05846  162 AATKFFLyTLLGsllmlVAIIYLVVVYYNATGTFDIADLlnlPLPPGvQYWLFLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 121 -TQGISLMTGMLLltwqKLAP---ISIMMQL---SSSINPTTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK05846  242 pTAGSVLLAGILL----KMGAyglLRFSLPLfpdASHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317


                  .
gi 1236513031 194 V 194
Cdd:PRK05846  318 L 318
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
94-193 2.09e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 43.15  E-value: 2.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  94 MLMSLTMIIALTMKLGMTPFHFWVP----EVTQGISLM-----------------TGMLLLTWQKLAPisimmqlsssin 152
Cdd:PRK06473  205 LLLLAPILVGFGIKIPLVPFHTWLPdahvEASTPVSVLlagvllklgtygllrfgVGLFPEAWVYLAP------------ 272

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1236513031 153 ptTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK06473  273 --WLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYIL 311
ndhD CHL00011
NADH dehydrogenase subunit 4
 55-194 2.92e-04

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 42.62  E-value: 2.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  55 AATKYFLTQATASMLLMFNIVFNAMYSGQWTTINI-DPNN--------MLMSLTMIIALTMKLGMTPFHFWVPEVTQGIS 125
Cdd:CHL00011  163 SATKFILYTAGGSIFLLIGVLGMGLYGSNEPTLNFeTLANqsypvaleILFYIGFLIAYAVKLPIIPLHTWLPDTHGEAH 242

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1236513031 126 LMTGMLL----LTWQKLAPISIMMQLSS---SINPTTLMLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMV 194
Cdd:CHL00011  243 YSTCMLLagilLKMGAYGLIRINMELLPhahSIFSPWLVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIII 318
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
85-194 3.06e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 42.39  E-value: 3.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  85 TTINIDPNNMLMSLTMI-IALTMKLGMTPFHFWVP----EVTQGISLMTGMLLLTWQKLAPISIMMQL---SSSINPTTL 156
Cdd:PRK07363  195 STQNLSLNTQLILLTGLlLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLfpqTWSLVAPGL 274

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1236513031 157 MLIALMSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMV 194
Cdd:PRK07363  275 AIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILV 312
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 49-196 3.74e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 42.45  E-value: 3.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  49 KPRSTEAATKYFLTQATASMLLMFNIVFNAMYSG--QWTTINIDPNNMLMSLTMIIALTM-------KLGMTPFHFWVPE 119
Cdd:COG1009   157 KPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGtlNFSELLAAAPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPD 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 120 -----------------VTQGISLMTgmllltwqKLAPIsimMQLSSSINpTTLMLIALMSVLIGGWGGLNQTQLRKILA 182
Cdd:COG1009   237 amegptpvsallhaatmVKAGVYLLA--------RLSPL---FALSPVWL-TVVAIIGAITALFAALIALAQTDIKRVLA 304

                         170
                  ....*....|....
gi 1236513031 183 YSSIAHMGWMMVIL 196
Cdd:COG1009   305 YSTVSQLGYMFLAL 318
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 102-213 3.67e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 38.88  E-value: 3.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 102 IALTMKLGMTPFHFWVPEV-----TQGISLMTGMLL---------LTWqKLAPISimmqlSSSINPTTLMLiALMSVLIG 167
Cdd:MTH00217  214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLLklggygfirFSW-PLLPEA-----SEYFSPLIQTL-SLLAIIYG 286

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1236513031 168 GWGGLNQTQLRKILAYSSIAHMGwmMVILTFYpSLTVLNLL--VYLML 213
Cdd:MTH00217  287 SLTTCRQVDLKRIIAYSSVAHMG--LVTLGIF-SHTIQGLVaaIFLML 331
PRK12650 PRK12650
DUF4040 family protein;
112-192 4.35e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 4.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031 112 PFHFWVPEVTQGISLMTGMLLLTWQKLAPISIMMQLSSSINPTT-----LMLIALMSVLIGGWGGLNQTQLRKILAYSSI 186
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVAvwnwlLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305


                  ....*.
gi 1236513031 187 AHMGWM 192
Cdd:PRK12650  306 SQLGWI 311
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-212 8.77e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 37.81  E-value: 8.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  17 TMLTMISSHWLLIWIGLEIN-MLSIIPILMKSPKpRSTEAATKYFLTQATA------SMLLMFNIVFNAMYSG--QWTTI 87
Cdd:PRK08676  115 ITFAFFSDNLALFWIFAELTtVFSAMLIAILSAR-ENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTEL 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1236513031  88 -----NIDPNNMLMS-LTMIIALTMKLGMTPFHFWVPEV-TQGISLMTGMLLLTWQKLAPISI-----MMQLSSSINPTT 155
Cdd:PRK08676  194 aahasLLSPSVLGASfLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGIlrlsaLLRQSGAAEQFS 273

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1236513031 156 LMLIAL--MSVLIGGWGGLNQTQLRKILAYSSIAHMGWMMVILTFYPSLTVLNLLVYLM 212
Cdd:PRK08676  274 NVLIGLgiFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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