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Conserved domains on  [gi|1237408470|ref|YP_009414928|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Microcebus berthae]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.18e-145

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 415.01  E-value: 1.18e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIdsNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQLQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.18e-145

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 415.01  E-value: 1.18e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIdsNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQLQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 4.82e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 96.56  E-value: 4.82e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS--VIPILAKNPKpRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCfyVLAGLKRKSR-FSTEAGLKYFILGAFSSGLLLFgisliygftgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  76 FNAMHSGQWTITNIDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLI---- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 152 ---NLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTT 228
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 229 TLT----------LSSLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRL 298
Cdd:TIGR01770 345 RSYkdewieyisdFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424


                  .
gi 1237408470 299 I 299
Cdd:TIGR01770 425 V 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 5.55e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 5.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIpILA--KNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWT 85
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  86 ITNID---SNNMLTSFTMIIALTM-------KLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLF--PLINL 153
Cdd:COG1007   185 LAGIAaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 154 N-----ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSM----TMLNLFVYLMLTITMFMMLNMN 224
Cdd:COG1007   265 AadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 225 TNTTTLTLS-----SLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLI 299
Cdd:COG1007   345 SRKGGEAEEiedlaGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424


                  .
gi 1237408470 300 Y 300
Cdd:COG1007   425 K 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-270 8.72e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 8.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  23 SSHWLLIWIGLEINMLSVIPILAKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNID---------SN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  93 NMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMIQLFPLIN-----LNILMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLM----LTITMFMMLNMNT-----NTTTLTLSSLWS 237
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLthglFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1237408470 238 KSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQ 270
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-349 1.18e-145

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 415.01  E-value: 1.18e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIdsNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00105   81 SGQWTITKL--TNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00105  159 ILSILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQLQ 320
Cdd:MTH00105  239 LMTSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFE 318

                         330       340
                  ....*....|....*....|....*....
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSPVFSTLN 349
Cdd:MTH00105  319 NTKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-348 8.16e-108

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 319.06  E-value: 8.16e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIdsNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLiNLNILMLIA 160
Cdd:MTH00135   81 TGQWDIQQM--SHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00135  158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAP 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQLQ 320
Cdd:MTH00135  238 ALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLP 317

                         330       340
                  ....*....|....*....|....*...
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSPVFSTL 348
Cdd:MTH00135  318 STQLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-343 1.05e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 308.39  E-value: 1.05e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIDSNnmLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00070   81 TGEWTIMNMQTP--LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWqLQ 320
Cdd:MTH00070  239 TLTSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYW-RF 317

                         330       340
                  ....*....|....*....|...
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSP 343
Cdd:MTH00070  318 KNKTNNLLSLTIILSLMLLPITP 340
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-348 1.51e-101

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 302.90  E-value: 1.51e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITNIdsNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00112   81 TGQWDITQL--TNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00112  159 ILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWQLQ 320
Cdd:MTH00112  239 TLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTK 318

                         330       340
                  ....*....|....*....|....*...
gi 1237408470 321 LKKQPLLLSPLIILSTLsLPLSPVFSTL 348
Cdd:MTH00112  319 PKKNTLTATLTTLSTLL-LPLSPMILTI 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-309 2.09e-74

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 233.67  E-value: 2.09e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTItnIDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00041   81 SGSWSI--NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00041  159 ILSVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNP 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPT 309
Cdd:MTH00041  239 ISAFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-348 2.83e-74

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 233.32  E-value: 2.83e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 SGQWTITniDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIA 160
Cdd:MTH00200   81 SGQWGIS--EMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00200  159 LLSVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNP 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKWqLQ 320
Cdd:MTH00200  239 ILSMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW-RT 317

                         330       340
                  ....*....|....*....|....*...
gi 1237408470 321 LKKQPLLLSPLIILSTLSLPLSPVFSTL 348
Cdd:MTH00200  318 KSNSNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-316 9.73e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 161.53  E-value: 9.73e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   1 MKPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  81 sgqwtitNIDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFpliNLNILMLIA 160
Cdd:MTH00160   81 -------NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIII 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 161 LLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSP 240
Cdd:MTH00160  151 ILSAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSK 230

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1237408470 241 TITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMK 316
Cdd:MTH00160  231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK 306
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-317 5.76e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 151.58  E-value: 5.76e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  10 MMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWtitni 89
Cdd:MTH00144   10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW----- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  90 dsnnmLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINL-NILMLIALLSVLAGG 168
Cdd:MTH00144   85 -----FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 169 WGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLwSKSPTITTMILV 248
Cdd:MTH00144  160 IGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIIS 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1237408470 249 SLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00144  239 LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-301 1.65e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.65e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   6 LMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWT 85
Cdd:MTH00011    8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLK 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  86 ITnidsnnmlTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIALLSVL 165
Cdd:MTH00011   88 NI--------TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 166 AGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSPTITTM 245
Cdd:MTH00011  160 AGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMS 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1237408470 246 ILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYS 301
Cdd:MTH00011  240 LFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 7-302 3.82e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 125.17  E-value: 3.82e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFtivfnamhsGQWTI 86
Cdd:MTH00197    1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  87 TNIDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPIsiMIQLFPLINLNILMLIALLSVLA 166
Cdd:MTH00197   72 FSNLYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTLSSLWSKSPTITTMI 246
Cdd:MTH00197  150 GGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFL 229

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1237408470 247 LVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYST 302
Cdd:MTH00197  230 GLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-300 5.85e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 102.02  E-value: 5.85e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILA-KNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQwti 86
Cdd:MTH00199  101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGE--- 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  87 TNIDSNNMLTS-----FTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLInlNILMLIAL 161
Cdd:MTH00199  178 TSIQGINSILTgdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVT--NVVLICAV 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 162 LSVLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMFCP-SMTMLNLFVYLMLTITMFMMLNMNTNTTTLT--LSSL 235
Cdd:MTH00199  256 LSIIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSIILSLKLTKGLIveVSGL 335

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1237408470 236 WSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIY 300
Cdd:MTH00199  336 SRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-299 4.82e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 96.56  E-value: 4.82e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLS--VIPILAKNPKpRSTEAATKYFLTQATASMLLMF----------TIV 75
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCfyVLAGLKRKSR-FSTEAGLKYFILGAFSSGLLLFgisliygftgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  76 FNAMHSGQWTITNIDSNNMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLI---- 151
Cdd:TIGR01770 185 FEDLLLFLSNGMLNISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 152 ---NLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTT 228
Cdd:TIGR01770 265 seaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 229 TLT----------LSSLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRL 298
Cdd:TIGR01770 345 RSYkdewieyisdFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424


                  .
gi 1237408470 299 I 299
Cdd:TIGR01770 425 V 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-299 1.67e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 93.94  E-value: 1.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  16 GTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKP-RSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNID-SNN 93
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINlVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  94 MLTSFT----------MIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPliNLNILMLIALLS 163
Cdd:MTH00196   85 SGQSFSsvsvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 164 VLAGGWGGLNQTQLRKILAYSSIAHMG---WMMAILMF-CPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTL--SSLWS 237
Cdd:MTH00196  163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFeSIQASLVYLFIYIIMSICVFSIILALNVYKNLIIefSGLSR 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1237408470 238 KSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLI 299
Cdd:MTH00196  243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-300 5.55e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 5.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   8 IIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIpILA--KNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWT 85
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  86 ITNID---SNNMLTSFTMIIALTM-------KLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLF--PLINL 153
Cdd:COG1007   185 LAGIAaalAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLveAFPGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 154 N-----ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSM----TMLNLFVYLMLTITMFMMLNMN 224
Cdd:COG1007   265 AadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 225 TNTTTLTLS-----SLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLI 299
Cdd:COG1007   345 SRKGGEAEEiedlaGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424


                  .
gi 1237408470 300 Y 300
Cdd:COG1007   425 K 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-270 8.72e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.84  E-value: 8.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  23 SSHWLLIWIGLEINMLSVIPILAKNPK-PRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNID---------SN 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKsPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSkaltgglnsSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  93 NMLTSFTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLL-TWQKLAPISIMIQLFPLIN-----LNILMLIALLSVLA 166
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 167 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLM----LTITMFMMLNMNT-----NTTTLTLSSLWS 237
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAIFHLLthglFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1237408470 238 KSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQ 270
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-299 4.14e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 79.09  E-value: 4.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  15 TGTMLTMISS-HWLLIWIGLEINMLS--VIPILAKNpKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNI-- 89
Cdd:PRK05777  113 LLGMMVMVSAnDLLTLFLGLELLSLPlyALAALRRD-RRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIak 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  90 -----DSNNMLTSFT---MIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLF-------PLINLN 154
Cdd:PRK05777  192 aladgSGNSLLLLFGlvfLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLvvafgglSEDWQQ 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 155 ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSM----TMLNLFVYLMLTITMFMMLNMNTNTTTL 230
Cdd:PRK05777  272 VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAFGVISLLRRKGGE 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1237408470 231 T-----LSSLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLI 299
Cdd:PRK05777  352 AesisdFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-193 2.41e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 67.96  E-value: 2.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  16 GTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRST---------EAATKYFLTQATASMLLMFTIVF---------- 76
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  77 -NAMHSGQWTITNIDSNNMLTSFTMI-IALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLfpLINLN 154
Cdd:MTH00198  280 lGTILSATLETTNIELRQGSLGYLFItVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VITSK 357

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1237408470 155 ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:MTH00198  358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-303 9.09e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.55  E-value: 9.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  15 TGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTIT------- 87
Cdd:COG0651   118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMAdlaarla 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  88 NIDSNNMLTSFTMI-IALTMKLGMAPFHFWVPEV----TQGVS-LMTGMLLltwqKLAPISIM---IQLFPLINLN---- 154
Cdd:COG0651   198 ELDPGLLLAAFALLlVGFGIKAALFPLHFWLPDAypaaPSPVSaLLSGLLT----KVGVYAILrvlTLLFGADPALflgt 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 155 ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYL----MLTITMF----MMLNMNTN 226
Cdd:COG0651   274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFlaagAIERATGT 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1237408470 227 TTTLTLSSLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTS 303
Cdd:COG0651   354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-194 1.28e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 59.32  E-value: 1.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  55 AATKYFLTQATASMLLMFTIVFNAMHSGQWT--ITNIDSNNMLTSFTMI------IALTMKLGMAPFHFWVPEV-----T 121
Cdd:COG1008   162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTfdIAELAAAPLPLTAQLLlflaffIAFAVKVPMFPFHTWLPDAhveapT 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1237408470 122 QGVSLMTGMLLltwqKLAP---ISIMIQLFP---LINLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMA 194
Cdd:COG1008   242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 4.12e-09

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 57.73  E-value: 4.12e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   2 KPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK12561   85 KPRLFYFLMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSG 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  82 GQWT--ITNIDSNNMLTSFTM------IIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFP 149
Cdd:PRK12561  165 DTFTfdLAELGAKSYPLALELllyagfLIAFGVKLPIFPLHTWLPdahgEASAPVSMILAGVLLKMGGYALIRFNVQMLP 244

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408470 150 LINLNILMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK12561  245 DAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSHMGFVL 291
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 6-193 5.28e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 57.26  E-value: 5.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   6 LMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNA-MHSGQW 84
Cdd:TIGR01972 108 FYALLLLLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILGLYfLGGGTF 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  85 TITNIDSNNMLTSFTMI------IALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAPISIM---IQLFP- 149
Cdd:TIGR01972 188 DLLELLNLPLPFGVQTWlflaffIAFAVKVPLFPLHTWLPDAhveapTAGSVILAGVLL----KMGTYGFLrfnLPLFPd 263

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1237408470 150 --LINLNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:TIGR01972 264 asLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
7-265 3.17e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 55.06  E-value: 3.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   7 MIIMMTIFTGTMLTMISSHWLLIWIGLEinMLSVIPILAK---NPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQ 83
Cdd:PRK02504  113 AAILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSSLLYGLSGG 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  84 WTITNIDSNNMLTSFTMIIALTM---------KLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLA----PISIMIQLFPL 150
Cdd:PRK02504  191 STQLSAIALALITSPSLGLALALvfviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPS 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 151 INLN---ILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMMaILMFCP-----SMTMLNLFVYLMLTITMFMMLN 222
Cdd:PRK02504  271 FDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFACVI 349

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408470 223 MNTNTT----TLTLSSLWSKSPTITTMILVSLLSLGGLPPLTGFLPK 265
Cdd:PRK02504  350 LFSLRTgtdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 2.98e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.80  E-value: 2.98e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  33 LEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGqwTITNIDSNNMLTSFT--------MIIAL 104
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTG--TLNMADLAGALAENPtvvtafgfVLLAL 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 105 TMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFP------LINLNILMLIALLSVLAGGWGGLNQ 174
Cdd:PRK08375  213 ALKAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGgdfrfaLGLGWLLAVLALLSMLVGSLAALGQ 292

                         170
                  ....*....|....*....
gi 1237408470 175 TQLRKILAYSSIAHMGWMM 193
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYIL 311
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-193 3.26e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 51.74  E-value: 3.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  55 AATKYFL-TQAT-----ASMLLMFTIVFNAMHS---GQWTITNIDSN-NMLTSFTMIIALTMKLGMAPFHFWVPEV---- 120
Cdd:PRK05846  162 AATKFFLyTLLGsllmlVAIIYLVVVYYNATGTfdiADLLNLPLPPGvQYWLFLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 121 -TQGVSLMTGMLLltwqKLAP---ISIMIQLFPLINLNILMLIALLSVLA---GGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK05846  242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-193 1.52e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.63  E-value: 1.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  33 LEINMLSVIPILA-KNPKPRSTEAATKYFLTQATASMLLMFTIvfnAMHSGQWTITNIDSNNMLTSFTM----------- 100
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSENPtvvakialalf 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 101 IIALTMKLGMAPFHFWVPEV-TQGVSLMTGMLLLTWQK--LAPISIMIQLF-PLINLN----ILMLIALLSVLAGGWGGL 172
Cdd:PRK08376  227 IAGLAMKSGAVPVHMWLPDAyPAAPSSISAMLLVIKQAglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAV 306

                         170       180
                  ....*....|....*....|.
gi 1237408470 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08376  307 VQKDVKRLLAYHSVSQIGYML 327
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 293-343 1.61e-04

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 38.78  E-value: 1.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1237408470 293 YFYMRLIYSTSLTLFPTPNNIKMKWQLQLKKQPLLLSPLIILSTLSLPLSP 343
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
100-193 1.79e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 43.15  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 100 MIIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNI---LMLIALLSVLAGGWGGL 172
Cdd:PRK06473  211 ILVGFGIKIPLVPFHTWLPdahvEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEAWVYLapwLATWAVVSVLYGASCAI 290

                          90       100
                  ....*....|....*....|.
gi 1237408470 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK06473  291 AQKDMKKMVAYSSIGHMGYIL 311
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-317 3.54e-04

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 41.78  E-value: 3.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  98 FTMIIALTMKLGMAPFHFWVPEVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIALLSVLAggwgGLNQTQL 177
Cdd:MTH00091   61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 178 RKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYLMLTITMFMMlnmntntttltlsslWSKSPTITTMILVSLLSLGGLP 257
Cdd:MTH00091  137 KNLLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPK---------------FNNVNKLNFVSWETLLVFMNLP 201

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 258 PLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYSTSLTLFPTPNNIKMKW 317
Cdd:MTH00091  202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 102-213 4.01e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 41.96  E-value: 4.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 102 IALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNILMLIALLSVLAGGWGGLN---Q 174
Cdd:MTH00217  214 LSLAIKIPKIPFHIWLPqahvEAPVAGSVILAGVLLKLGGYGFIRFSWPLLPEASEYFSPLIQTLSLLAIIYGSLTtcrQ 293

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1237408470 175 TQLRKILAYSSIAHMGwMMAILMFCPSMTMLNLFVYLML 213
Cdd:MTH00217  294 VDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 4-193 5.87e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.66  E-value: 5.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   4 LILMIIMMTIFTGTMLtmisshwlLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATA------SMLLMFTIVFN 77
Cdd:PRK08676  110 LLLSVITFAFFSDNLA--------LFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQ 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  78 AMHSG--QWT-----ITNIDSNNMLTSFT-MIIALTMKLGMAPFHFWVPEV-TQGVSLMTGMLLLTWQKLAPISImIQLF 148
Cdd:PRK08676  182 ALGTGtlNWTelaahASLLSPSVLGASFLfIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGI-LRLS 260

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1237408470 149 PLIN--------LNILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK08676  261 ALLRqsgaaeqfSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 17-301 6.91e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 41.34  E-value: 6.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  17 TMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFT---IVFNAMHSGQWTITNIDSNN 93
Cdd:PRK06589  129 GVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPaviLIYTKTGNLDFVSGGLFSKN 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  94 M-LTSFTMIIALTMKLGMAPFHFWVPEV----TQGVSLMTGMLLLTWQKLAPISIMIQLFPLINL-------NILMLIAL 161
Cdd:PRK06589  209 QsIILLLMFIYGIAKTAIFPVHSWLPAAmvahYPVSALLHAVIVVKTGLFCIYKILLYIFGLSYLqrifaefNWLIFIPI 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 162 LSVLAGGWGGLNQTQLRKILAYSSIAHMGWMM--AILMFCPSM--TMLNLFVYLMLTITMFMMLNMNTNTT----TLTLS 233
Cdd:PRK06589  289 VSIFYSSLKALKTDNIKKILAYSTISQLSLALlsAFILTPKALgaAILHLVSHSFAKICLFYSMGSIYSLKkedqVDKLH 368

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1237408470 234 SLWSKSPTITTMILVSLLSLGGLPPLTGFLPKWLIIQELTKNNN----IIVATMMTIMALLNLYFYMRLIYS 301
Cdd:PRK06589  369 GTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQpwlsIIVMLVVIASSILSALYLLKILSS 440
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-192 1.08e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 40.68  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  10 MMTIFTGTM-LTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFL------TQATASMLLMFTIVFNAMHSG 82
Cdd:PRK06458  113 MYQLFLFTMlLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  83 Q----WTITN-----IDSNNMLTSFTMI-IALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISI-MIQL 147
Cdd:PRK06458  193 EmailWTELLkhaslLDPTLMKLAFVFLlIGFGTKVGLFPMHAWLPdahsEAPSPVSALLSGVLLNVALYAVLRYyILID 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1237408470 148 FPLINL---NILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGWM 192
Cdd:PRK06458  273 AAIGSDfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 2-193 1.15e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 40.85  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470   2 KPLILMIIMMTIFTGTMLTMISSHWLLIWIGLEINMLSVIPILAKNPKPRSTEAATKYFLTQATASMLLMFTIVFNAMHS 81
Cdd:PRK02546  113 KPKLFYFLMLAMYGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMAFYG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  82 GQWT--ITNIDSNNMLTSFTM------IIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFP 149
Cdd:PRK02546  193 DTPTfdMTALAAKDFGLGFQLlcyaglLIAYGVKLPIVPLHTWLPdahgEATAPVHMLLAGILLKMGGYALLRMNAGMLP 272

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1237408470 150 LINLNILMLIALLSVLAGGWGGLN---QTQLRKILAYSSIAHMGWMM 193
Cdd:PRK02546  273 DAHAQFAPLLIVLGVVNIIYAALTsfaQRNLKRKIAYSSISHMGFVL 319
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 102-213 1.38e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.43  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 102 IALTMKLGMAPFHFWVPEV-----TQGVSLMTGMLLltwqKLAP---ISIMIQLFPLINLNILMLIALLSVLAGGWGGL- 172
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGygfLRFSWPLFPAASEYFAPLIVMLSVIAVIYGSLt 292

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1237408470 173 --NQTQLRKILAYSSIAHMGwMMAILMFCPSMTMLNLFVYLML 213
Cdd:MTH00204  293 tcRQVDFKRLIAYSSVAHMG-LVPLGLFTHTIEGLVAAVFLML 334
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-299 1.83e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.99  E-value: 1.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  51 RSTEAATKYFLTQATASMLLMFTIVFNAMHSGQ----WTITN-IDSNNMLTSFTMIIALT-------MKLGMAPFHFWVP 118
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGFSWLYGLSGGeielQEIVNgLINTQMYNSPGISIALIfitvgigFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 119 EVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINL-------NILMLIALLSVLAGGWGGLNQTQLRKILAYSSIAHMGW 191
Cdd:CHL00049  239 DVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYfssnewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 192 MM-AILMFCPSMTMLNLFVYLMLTITMFMMLNMNTNTTTLTL--------SSLWSKSPTITTMILVSLLSLGGLPPLTGF 262
Cdd:CHL00049  319 VIiGIIVGDSNDGYASMITYMLFYIFMNLGTFACIVLFGLRTgtdnirdyAGLYTKDPFLALSLALCLLSLGGIPPLAGF 398

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1237408470 263 LPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLI 299
Cdd:CHL00049  399 FGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
100-193 3.51e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 39.31  E-value: 3.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 100 MIIALTMKLGMAPFHFWVP----EVTQGVSLMTGMLLLTWQKLAPISIMIQLFPLINLNI---LMLIALLSVLAGGWGGL 172
Cdd:PRK07363  211 LLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPQTWSLVapgLAIIGTISVIYGALSAI 290

                          90       100
                  ....*....|....*....|.
gi 1237408470 173 NQTQLRKILAYSSIAHMGWMM 193
Cdd:PRK07363  291 AQKDIKRMVAYSSIGHMGYIL 311
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 49-301 3.68e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 39.18  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470  49 KPRSTEAATKYFLTQATASMLLMFTIVFNAMHSGQWTITNIDSNNMLTSFTM-------------------IIALTMKLG 109
Cdd:PRK12667  159 RGDAVEAAIKYALIGAVGTTLYFLALAFLYATFGTLNMADLSAKIRGLSFPLtgglagnpplalgvalalaLWAFTIKAA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 110 MAPFHFWVPEV----TQGVSLMTGMLLLTWQKLAPISIM-------IQLFPLIN--LNILMLIALLSVLAGGWGGLNQTQ 176
Cdd:PRK12667  239 IFPNHFWLPDAhpaaPSPVSAMLSGLVVNVGAYAIIRFLytifgisPSLIDFRAalSPILIILGAVSAIIGALMMVVQKD 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1237408470 177 LRKILAYSSIAHMGWMMAILMFCPSMTMLNLFVYL--------MLTITMFMMLNMNTNTTTLTLSSLWSKSPTITTMILV 248
Cdd:PRK12667  319 VKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLI 398

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1237408470 249 SLLSLGGLPPLTGFLPKWLIIQELTKNNNIIVATMMTIMALLNLYFYMRLIYS 301
Cdd:PRK12667  399 GALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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